Project
PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap
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Results for AAUGCCC
Z-value: 0.57
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miRNA associated with seed AAUGCCC
| Name | miRBASE accession |
|---|---|
|
mmu-miR-365-3p
|
MIMAT0000711 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAUGCCC
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_103133524 Show fit | 4.63 |
ENSMUST00000090475.10
|
ets homologous factor |
|
| chr16_+_34605282 Show fit | 3.94 |
ENSMUST00000023538.9
|
myosin, light polypeptide kinase |
|
| chr5_+_64960705 Show fit | 3.51 |
ENSMUST00000165536.8
|
Kruppel-like factor 3 (basic) |
|
| chr1_-_64776890 Show fit | 3.03 |
ENSMUST00000116133.4
ENSMUST00000063982.7 |
frizzled class receptor 5 |
|
| chr13_+_81031512 Show fit | 2.78 |
ENSMUST00000099356.10
|
arrestin domain containing 3 |
|
| chr1_-_13660027 Show fit | 2.74 |
ENSMUST00000027068.11
|
translocating chain-associating membrane protein 1 |
|
| chr6_-_52203146 Show fit | 2.64 |
ENSMUST00000114425.3
|
homeobox A9 |
|
| chrX_-_141749704 Show fit | 2.62 |
ENSMUST00000041317.3
|
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
|
| chr18_-_61533434 Show fit | 2.60 |
ENSMUST00000063307.6
ENSMUST00000075299.13 |
peroxisome proliferative activated receptor, gamma, coactivator 1 beta |
|
| chr11_-_53313950 Show fit | 2.50 |
ENSMUST00000036045.6
|
liver-expressed antimicrobial peptide 2 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.0 | 3.0 | GO:0060715 | Spemann organizer formation(GO:0060061) syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.7 | 2.8 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 0.2 | 2.6 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.4 | 2.5 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.3 | 2.1 | GO:1904073 | regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.1 | 2.1 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.0 | 2.1 | GO:0040036 | regulation of fibroblast growth factor receptor signaling pathway(GO:0040036) |
| 0.5 | 2.0 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 2.0 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 3.0 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 2.9 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 2.6 | GO:0016592 | mediator complex(GO:0016592) |
| 0.2 | 2.1 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 2.0 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.4 | 1.8 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 1.6 | GO:0070578 | micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578) |
| 0.0 | 1.5 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 1.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.7 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.4 | 3.9 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 3.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 3.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.7 | 2.8 | GO:0031699 | beta-3 adrenergic receptor binding(GO:0031699) |
| 0.0 | 2.6 | GO:0030546 | receptor activator activity(GO:0030546) |
| 0.1 | 2.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 2.1 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.1 | 2.1 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 2.1 | GO:0042379 | chemokine receptor binding(GO:0042379) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 3.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 3.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 2.5 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.1 | 2.1 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 2.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.8 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 1.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.3 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 3.8 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 2.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 2.7 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 2.1 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 2.0 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.1 | 1.8 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 1.8 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 1.6 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.5 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |