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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for ACCCUGU

Z-value: 0.49

Motif logo

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miRNA associated with seed ACCCUGU

NamemiRBASE accession
mmu-miR-10a-5p
MIMAT0000648
mmu-miR-10b-5p
MIMAT0000208

Activity profile of ACCCUGU motif

Sorted Z-values of ACCCUGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCCUGU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_74769166 3.21 ENSMUST00000056006.11
Onecut1
one cut domain, family member 1
chr4_-_91260265 2.31 ENSMUST00000107110.8
ENSMUST00000008633.15
ENSMUST00000107118.8
Elavl2
ELAV like RNA binding protein 1
chr12_+_29578354 2.25 ENSMUST00000218583.2
ENSMUST00000049784.17
Myt1l
myelin transcription factor 1-like
chr6_-_136150076 2.19 ENSMUST00000053880.13
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr13_+_117738972 2.10 ENSMUST00000006991.9
Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
chr5_+_125609440 2.04 ENSMUST00000031446.7
Tmem132b
transmembrane protein 132B
chr15_+_85619958 1.84 ENSMUST00000109422.8
Ppara
peroxisome proliferator activated receptor alpha
chr1_+_153528689 1.82 ENSMUST00000041776.12
Rgs8
regulator of G-protein signaling 8
chr8_+_14145848 1.77 ENSMUST00000152652.8
ENSMUST00000133298.8
Dlgap2
DLG associated protein 2
chr6_-_113172340 1.70 ENSMUST00000162280.2
Lhfpl4
lipoma HMGIC fusion partner-like protein 4
chr12_-_75224099 1.68 ENSMUST00000042299.4
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr11_+_42310557 1.45 ENSMUST00000007797.10
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr15_+_39061612 1.41 ENSMUST00000082054.12
ENSMUST00000227243.2
ENSMUST00000042917.10
Rims2
regulating synaptic membrane exocytosis 2
chr9_+_68561042 1.39 ENSMUST00000034766.14
Rora
RAR-related orphan receptor alpha
chr10_-_43050516 1.36 ENSMUST00000040275.9
Sobp
sine oculis binding protein
chr7_+_46445512 1.35 ENSMUST00000006774.11
ENSMUST00000165031.8
Gtf2h1
general transcription factor II H, polypeptide 1
chr6_+_103487973 1.35 ENSMUST00000066905.9
Chl1
cell adhesion molecule L1-like
chr9_+_72714156 1.27 ENSMUST00000055535.9
Prtg
protogenin
chr11_-_37126709 1.23 ENSMUST00000102801.8
Tenm2
teneurin transmembrane protein 2
chr16_-_17745999 1.23 ENSMUST00000003622.16
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr6_-_120470768 1.22 ENSMUST00000178687.2
Tmem121b
transmembrane protein 121B
chr2_-_73722874 1.19 ENSMUST00000136958.8
ENSMUST00000112010.9
ENSMUST00000128531.8
ENSMUST00000112017.8
Atf2
activating transcription factor 2
chr6_-_113478779 1.16 ENSMUST00000101059.4
ENSMUST00000204268.3
ENSMUST00000205170.2
ENSMUST00000205075.2
ENSMUST00000204134.3
Prrt3
proline-rich transmembrane protein 3
chr18_-_77652820 1.11 ENSMUST00000026494.14
ENSMUST00000182024.2
Rnf165
ring finger protein 165
chr11_-_6015736 1.08 ENSMUST00000002817.12
ENSMUST00000109813.9
ENSMUST00000090443.10
Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chr7_-_109092834 1.07 ENSMUST00000106739.8
Trim66
tripartite motif-containing 66
chr4_-_49845549 1.03 ENSMUST00000093859.11
ENSMUST00000076674.4
Grin3a
glutamate receptor ionotropic, NMDA3A
chr19_-_18978463 1.01 ENSMUST00000040153.15
ENSMUST00000112828.8
Rorb
RAR-related orphan receptor beta
chr7_-_134539993 0.98 ENSMUST00000171394.3
Insyn2a
inhibitory synaptic factor 2A
chr11_-_103640640 0.91 ENSMUST00000018630.3
Wnt9b
wingless-type MMTV integration site family, member 9B
chr2_+_65676111 0.89 ENSMUST00000122912.8
Csrnp3
cysteine-serine-rich nuclear protein 3
chrX_-_87159237 0.87 ENSMUST00000113966.8
ENSMUST00000113964.2
Il1rapl1
interleukin 1 receptor accessory protein-like 1
chr12_-_80807454 0.85 ENSMUST00000073251.8
Ccdc177
coiled-coil domain containing 177
chr11_+_74510413 0.85 ENSMUST00000100866.3
Ccdc92b
coiled-coil domain containing 92B
chr8_-_17585263 0.82 ENSMUST00000082104.7
Csmd1
CUB and Sushi multiple domains 1
chr4_+_57434247 0.80 ENSMUST00000102905.8
Pakap
paralemmin A kinase anchor protein
chr14_+_67470884 0.79 ENSMUST00000176161.8
Ebf2
early B cell factor 2
chr19_+_45352173 0.76 ENSMUST00000223764.2
ENSMUST00000065601.13
ENSMUST00000224102.2
ENSMUST00000111936.4
Btrc
beta-transducin repeat containing protein
chrX_+_149981074 0.74 ENSMUST00000184730.8
ENSMUST00000184392.8
ENSMUST00000096285.5
Wnk3
WNK lysine deficient protein kinase 3
chr3_-_84212069 0.73 ENSMUST00000107692.8
Trim2
tripartite motif-containing 2
chr3_-_152687877 0.66 ENSMUST00000044278.6
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_-_83173708 0.65 ENSMUST00000039956.6
Slc41a2
solute carrier family 41, member 2
chr1_-_136888118 0.59 ENSMUST00000192357.6
ENSMUST00000027649.14
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr16_-_67417768 0.59 ENSMUST00000114292.8
ENSMUST00000120898.8
Cadm2
cell adhesion molecule 2
chr4_+_149602673 0.59 ENSMUST00000030839.13
Ctnnbip1
catenin beta interacting protein 1
chr5_-_74229021 0.58 ENSMUST00000119154.8
ENSMUST00000068058.14
Usp46
ubiquitin specific peptidase 46
chr4_+_124696336 0.58 ENSMUST00000138807.8
ENSMUST00000030723.3
Mtf1
metal response element binding transcription factor 1
chr2_+_172391501 0.57 ENSMUST00000030391.9
Tfap2c
transcription factor AP-2, gamma
chr19_+_32734884 0.57 ENSMUST00000013807.8
Pten
phosphatase and tensin homolog
chr2_-_63928339 0.56 ENSMUST00000131615.9
Fign
fidgetin
chr9_+_21077010 0.56 ENSMUST00000039413.15
Pde4a
phosphodiesterase 4A, cAMP specific
chr4_+_139302009 0.54 ENSMUST00000174078.2
Iffo2
intermediate filament family orphan 2
chr1_-_134289670 0.47 ENSMUST00000049470.11
Tmem183a
transmembrane protein 183A
chr12_-_119202527 0.45 ENSMUST00000026360.9
Itgb8
integrin beta 8
chr4_-_136684082 0.44 ENSMUST00000030420.9
Epha8
Eph receptor A8
chr6_-_126717590 0.43 ENSMUST00000185333.2
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr9_-_48747232 0.43 ENSMUST00000093852.5
Zbtb16
zinc finger and BTB domain containing 16
chr12_+_64964674 0.42 ENSMUST00000058135.6
ENSMUST00000220993.2
Gm527
predicted gene 527
chr2_+_32496990 0.41 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr3_+_146110387 0.41 ENSMUST00000106151.8
ENSMUST00000106153.9
ENSMUST00000039021.11
ENSMUST00000106149.8
ENSMUST00000149262.8
Ssx2ip
synovial sarcoma, X 2 interacting protein
chr8_-_40095706 0.40 ENSMUST00000210525.2
ENSMUST00000170091.3
Msr1
macrophage scavenger receptor 1
chr2_+_121859025 0.39 ENSMUST00000028668.8
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr18_-_61533434 0.38 ENSMUST00000063307.6
ENSMUST00000075299.13
Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr1_-_23961379 0.35 ENSMUST00000027339.14
Smap1
small ArfGAP 1
chr15_+_84807582 0.34 ENSMUST00000165443.4
Nup50
nucleoporin 50
chr13_-_40887244 0.32 ENSMUST00000110193.9
Tfap2a
transcription factor AP-2, alpha
chr3_+_51323383 0.28 ENSMUST00000029303.13
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr9_-_108526548 0.25 ENSMUST00000013338.14
ENSMUST00000193197.6
Arih2
ariadne RBR E3 ubiquitin protein ligase 2
chr7_+_5353536 0.24 ENSMUST00000056639.8
Gm5065
predicted gene 5065
chr2_-_65397809 0.24 ENSMUST00000066432.12
Scn3a
sodium channel, voltage-gated, type III, alpha
chr15_+_80118219 0.24 ENSMUST00000023048.12
Mief1
mitochondrial elongation factor 1
chr1_+_187730018 0.23 ENSMUST00000027906.13
Esrrg
estrogen-related receptor gamma
chr5_+_65694552 0.23 ENSMUST00000142407.8
Ube2k
ubiquitin-conjugating enzyme E2K
chr1_+_70764874 0.22 ENSMUST00000053922.12
ENSMUST00000161937.2
ENSMUST00000162182.2
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr1_-_67077906 0.20 ENSMUST00000119559.8
ENSMUST00000149996.2
ENSMUST00000027149.12
ENSMUST00000113979.10
Lancl1
LanC (bacterial lantibiotic synthetase component C)-like 1
chr8_-_27618643 0.19 ENSMUST00000033877.6
Brf2
BRF2, RNA polymerase III transcription initiation factor 50kDa subunit
chr19_-_5168251 0.18 ENSMUST00000113728.8
ENSMUST00000113727.8
ENSMUST00000025798.13
Klc2
kinesin light chain 2
chr9_+_59485475 0.17 ENSMUST00000118549.8
ENSMUST00000034840.10
Celf6
CUGBP, Elav-like family member 6
chr11_+_72580823 0.17 ENSMUST00000155998.2
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr10_+_11157047 0.16 ENSMUST00000129456.8
Fbxo30
F-box protein 30
chr13_+_44884740 0.16 ENSMUST00000173246.8
Jarid2
jumonji, AT rich interactive domain 2
chr3_-_104419128 0.14 ENSMUST00000199070.5
ENSMUST00000046316.11
ENSMUST00000198332.2
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr8_+_88925821 0.13 ENSMUST00000066748.10
ENSMUST00000119033.8
ENSMUST00000118952.8
Tent4b
terminal nucleotidyltransferase 4B
chr2_-_50186690 0.11 ENSMUST00000144143.8
ENSMUST00000102769.11
ENSMUST00000133768.2
Mmadhc
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr8_-_85526653 0.10 ENSMUST00000126806.2
ENSMUST00000076715.13
Nfix
nuclear factor I/X
chr1_-_13660027 0.10 ENSMUST00000027068.11
Tram1
translocating chain-associating membrane protein 1
chr7_-_46658144 0.10 ENSMUST00000061639.10
Spty2d1
SPT2 chromatin protein domain containing 1
chr14_+_55120875 0.09 ENSMUST00000134077.2
ENSMUST00000172844.8
ENSMUST00000133397.4
ENSMUST00000227108.2
Gm20521
Bcl2l2
predicted gene 20521
BCL2-like 2
chr11_-_118103540 0.08 ENSMUST00000106302.9
ENSMUST00000151165.2
Cyth1
cytohesin 1
chr1_-_155848917 0.07 ENSMUST00000138762.8
Cep350
centrosomal protein 350
chr1_-_181039509 0.06 ENSMUST00000162819.9
ENSMUST00000237749.2
Wdr26
WD repeat domain 26
chr8_-_85414528 0.06 ENSMUST00000001975.6
Nacc1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr13_+_81031512 0.06 ENSMUST00000099356.10
Arrdc3
arrestin domain containing 3
chr1_-_63153675 0.06 ENSMUST00000097718.9
Ino80d
INO80 complex subunit D
chr11_-_20781009 0.05 ENSMUST00000047028.9
Lgalsl
lectin, galactoside binding-like
chr7_+_49559859 0.04 ENSMUST00000056442.12
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr4_+_31964082 0.04 ENSMUST00000037607.11
ENSMUST00000080933.13
ENSMUST00000108183.8
ENSMUST00000108184.3
Map3k7
mitogen-activated protein kinase kinase kinase 7
chr11_-_4544751 0.04 ENSMUST00000109943.10
Mtmr3
myotubularin related protein 3
chr10_+_74896383 0.03 ENSMUST00000164107.3
Bcr
BCR activator of RhoGEF and GTPase
chr11_-_97078698 0.03 ENSMUST00000001479.5
Kpnb1
karyopherin (importin) beta 1
chr14_+_34395845 0.03 ENSMUST00000048263.14
Wapl
WAPL cohesin release factor
chrX_-_13712746 0.00 ENSMUST00000115436.9
ENSMUST00000033321.11
ENSMUST00000115438.10
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr2_-_168443540 0.00 ENSMUST00000171689.8
ENSMUST00000137451.2
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 2.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 1.8 GO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.4 1.1 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.3 1.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 1.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.7 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 1.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 0.6 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 0.9 GO:0072181 mesonephric duct formation(GO:0072181)
0.1 0.6 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 1.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.0 GO:0046549 retinal cone cell development(GO:0046549)
0.1 2.7 GO:0060384 innervation(GO:0060384)
0.1 1.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.9 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 1.0 GO:0060134 prepulse inhibition(GO:0060134)
0.1 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 2.8 GO:0048536 spleen development(GO:0048536)
0.0 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.8 GO:0001964 startle response(GO:0001964)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.4 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.3 GO:0035640 exploration behavior(GO:0035640)
0.0 1.0 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.0 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0098855 HCN channel complex(GO:0098855)
0.2 0.9 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.3 GO:0000439 core TFIIH complex(GO:0000439)
0.1 3.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 1.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 2.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 2.2 GO:0050897 retinoic acid-responsive element binding(GO:0044323) cobalt ion binding(GO:0050897)
0.1 1.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.9 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 1.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway