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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap
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Results for AGCACCA
Z-value: 1.85
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miRNA associated with seed AGCACCA
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 29.6 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.6 | 18.0 | GO:0032060 | bleb assembly(GO:0032060) |
| 4.1 | 16.5 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 2.0 | 16.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 3.3 | 13.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 2.3 | 11.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 10.9 | GO:0030038 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.2 | 9.9 | GO:0036344 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.4 | 9.4 | GO:0001553 | luteinization(GO:0001553) |
| 1.3 | 8.9 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 34.9 | GO:0098651 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.1 | 32.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 32.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 1.4 | 23.1 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 6.3 | 18.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 16.9 | GO:0005604 | basement membrane(GO:0005604) |
| 5.6 | 16.8 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.0 | 15.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.3 | 12.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.9 | 11.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 45.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 2.4 | 41.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 28.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 14.9 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.1 | 14.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 2.0 | 9.9 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 9.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 9.3 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.3 | 9.0 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.3 | 8.9 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 96.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 55.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 31.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 17.4 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.2 | 9.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.3 | 9.7 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 9.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.3 | 8.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 6.8 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 6.1 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 115.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.5 | 12.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.3 | 11.0 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.4 | 9.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 8.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 8.0 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.2 | 7.8 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 7.2 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.3 | 7.0 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.3 | 6.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |