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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for AGCUUAU

Z-value: 0.74

Motif logo

miRNA associated with seed AGCUUAU

NamemiRBASE accession
MIMAT0000530
MIMAT0025148
MIMAT0004895

Activity profile of AGCUUAU motif

Sorted Z-values of AGCUUAU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCUUAU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_64960705 6.13 ENSMUST00000165536.8
Kruppel-like factor 3 (basic)
chr2_-_136958544 5.50 ENSMUST00000028735.8
jagged 1
chr13_+_56757389 5.43 ENSMUST00000045173.10
transforming growth factor, beta induced
chr3_-_131138541 4.38 ENSMUST00000090246.5
ENSMUST00000126569.2
sphingomyelin synthase 2
chr13_-_111945499 4.17 ENSMUST00000109267.9
mitogen-activated protein kinase kinase kinase 1
chr11_+_60822859 3.95 ENSMUST00000019076.10
mitogen-activated protein kinase kinase 3
chr4_-_3938352 3.88 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr11_+_85723377 3.84 ENSMUST00000000095.7
T-box 2
chr15_+_85619958 3.40 ENSMUST00000109422.8
peroxisome proliferator activated receptor alpha
chr16_+_4412546 3.38 ENSMUST00000014447.13
GLIS family zinc finger 2
chr15_-_73056713 3.31 ENSMUST00000044113.12
argonaute RISC catalytic subunit 2
chr6_-_14755249 3.20 ENSMUST00000045096.6
protein phosphatase 1, regulatory subunit 3A
chr4_+_8691303 2.91 ENSMUST00000051558.10
chromodomain helicase DNA binding protein 7
chr6_-_39183712 2.91 ENSMUST00000002305.9
lysine (K)-specific demethylase 7A
chr18_+_75500600 2.87 ENSMUST00000026999.10
SMAD family member 7
chr13_-_101904662 2.86 ENSMUST00000055518.13
phosphoinositide-3-kinase regulatory subunit 1
chr3_+_60408600 2.63 ENSMUST00000099087.8
muscleblind like splicing factor 1
chr4_+_97665843 2.63 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr19_+_6326755 2.57 ENSMUST00000025684.4
EH-domain containing 1
chr18_+_84106188 2.55 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr5_+_52521133 2.50 ENSMUST00000101208.6
superoxide dismutase 3, extracellular
chr11_+_21041291 2.46 ENSMUST00000093290.12
pellino 1
chr9_-_8004586 2.43 ENSMUST00000086580.12
ENSMUST00000065353.13
yes-associated protein 1
chr1_-_74163575 2.43 ENSMUST00000169786.8
ENSMUST00000212888.2
ENSMUST00000191104.7
tensin 1
chr2_-_104324745 2.31 ENSMUST00000028600.14
homeodomain interacting protein kinase 3
chr11_+_60308077 2.29 ENSMUST00000070681.7
GID complex subunit 4, VID24 homolog
chr5_+_102629240 2.27 ENSMUST00000073302.12
ENSMUST00000094559.9
Rho GTPase activating protein 24
chr4_-_19708910 2.25 ENSMUST00000108246.9
WW domain containing E3 ubiquitin protein ligase 1
chr5_-_136596299 2.24 ENSMUST00000004097.16
cut-like homeobox 1
chr10_+_86136236 2.18 ENSMUST00000020234.14
tissue inhibitor of metalloproteinase 3
chrX_+_41238193 2.14 ENSMUST00000115073.9
ENSMUST00000115072.8
stromal antigen 2
chr14_+_64181115 2.10 ENSMUST00000079652.7
SRY (sex determining region Y)-box 7
chr10_-_61288437 2.01 ENSMUST00000167087.2
ENSMUST00000020288.15
eukaryotic translation initiation factor 4E binding protein 2
chr9_-_85209162 1.89 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr1_-_134006847 1.80 ENSMUST00000020692.7
BTG anti-proliferation factor 2
chr4_-_155306992 1.74 ENSMUST00000084103.10
ENSMUST00000030917.6
ski sarcoma viral oncogene homolog (avian)
chr2_-_102731691 1.65 ENSMUST00000111192.3
ENSMUST00000111190.9
ENSMUST00000111198.9
ENSMUST00000111191.9
ENSMUST00000060516.14
ENSMUST00000099673.9
ENSMUST00000005218.15
ENSMUST00000111194.8
CD44 antigen
chr19_+_41471067 1.65 ENSMUST00000067795.13
ligand dependent nuclear receptor corepressor
chr16_-_4340920 1.65 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chr5_+_3393893 1.64 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chr3_+_37694094 1.62 ENSMUST00000108109.8
ENSMUST00000038569.8
ENSMUST00000108107.2
sprouty RTK signaling antagonist 1
chr9_-_116004265 1.61 ENSMUST00000061101.12
transforming growth factor, beta receptor II
chr2_+_109747984 1.56 ENSMUST00000046548.14
ENSMUST00000111037.3
leucine-rich repeat-containing G protein-coupled receptor 4
chrX_+_159173680 1.56 ENSMUST00000112408.9
ENSMUST00000112402.8
ENSMUST00000112401.8
ENSMUST00000112400.8
ENSMUST00000112405.9
ENSMUST00000112404.9
ENSMUST00000146805.8
adhesion G protein-coupled receptor G2
chr18_+_36414122 1.50 ENSMUST00000051301.6
purine rich element binding protein A
chr4_-_123644091 1.49 ENSMUST00000102636.4
akirin 1
chr7_+_65511777 1.38 ENSMUST00000055576.12
ENSMUST00000098391.11
proprotein convertase subtilisin/kexin type 6
chr4_+_99952988 1.38 ENSMUST00000039630.6
receptor tyrosine kinase-like orphan receptor 1
chr4_-_82423985 1.30 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr5_-_50216249 1.29 ENSMUST00000030971.7
adhesion G protein-coupled receptor A3
chr13_-_99027544 1.26 ENSMUST00000109399.9
transportin 1
chr15_+_80595486 1.25 ENSMUST00000067689.9
trinucleotide repeat containing 6b
chr14_-_4808744 1.23 ENSMUST00000022303.17
ENSMUST00000091471.12
thyroid hormone receptor beta
chr6_-_71417607 1.23 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr8_-_112603292 1.22 ENSMUST00000034431.3
transmembrane protein 170
chr10_-_102864904 1.20 ENSMUST00000167156.9
ALX homeobox 1
chr13_+_5911481 1.20 ENSMUST00000000080.8
Kruppel-like factor 6
chr9_-_43017249 1.12 ENSMUST00000165665.9
Rho guanine nucleotide exchange factor (GEF) 12
chr7_-_119494918 1.11 ENSMUST00000059851.14
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr11_-_49603501 1.10 ENSMUST00000020624.7
ENSMUST00000145353.8
CCR4-NOT transcription complex, subunit 6
chr3_-_51184895 1.04 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr2_-_148250024 1.00 ENSMUST00000099270.5
thrombomodulin
chr6_+_14901343 0.95 ENSMUST00000115477.8
forkhead box P2
chr16_-_46317318 0.94 ENSMUST00000023335.13
ENSMUST00000023334.15
nectin cell adhesion molecule 3
chr18_+_56565188 0.88 ENSMUST00000070166.6
GRAM domain containing 3
chr3_+_137770813 0.87 ENSMUST00000163080.3
RIKEN cDNA 1110002E22 gene
chr11_-_118977047 0.87 ENSMUST00000026665.8
chromobox 4
chr3_+_128993568 0.85 ENSMUST00000029657.16
ENSMUST00000106382.11
paired-like homeodomain transcription factor 2
chr14_-_21102487 0.84 ENSMUST00000154460.8
ENSMUST00000130291.8
adaptor-related protein complex 3, mu 1 subunit
chr2_-_126718129 0.84 ENSMUST00000103224.10
transient receptor potential cation channel, subfamily M, member 7
chrX_+_158038778 0.84 ENSMUST00000126686.8
ENSMUST00000033671.13
ribosomal protein S6 kinase polypeptide 3
chr3_-_89820451 0.82 ENSMUST00000029559.7
ENSMUST00000197679.5
interleukin 6 receptor, alpha
chr13_-_85437118 0.81 ENSMUST00000109552.3
RAS p21 protein activator 1
chr2_-_168048795 0.80 ENSMUST00000057793.11
activity-dependent neuroprotective protein
chr1_-_178165223 0.78 ENSMUST00000037748.9
heterogeneous nuclear ribonucleoprotein U
chr13_-_115238427 0.76 ENSMUST00000224997.2
ENSMUST00000061673.9
predicted gene, 49395
integrin alpha 1
chr17_-_63806963 0.75 ENSMUST00000024761.13
F-box and leucine-rich repeat protein 17
chr9_+_109704609 0.75 ENSMUST00000094324.8
cell division cycle 25A
chr4_+_43875524 0.74 ENSMUST00000030198.7
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_129484070 0.72 ENSMUST00000183258.8
ENSMUST00000182784.4
ENSMUST00000032265.13
ENSMUST00000162815.2
oxidized low density lipoprotein (lectin-like) receptor 1
chr2_+_79465696 0.72 ENSMUST00000111785.9
ITPR interacting domain containing 2
chr17_-_84495364 0.71 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr10_+_53473032 0.68 ENSMUST00000020004.8
anti-silencing function 1A histone chaperone
chr6_+_66873381 0.65 ENSMUST00000043148.13
ENSMUST00000114228.8
ENSMUST00000114227.8
ENSMUST00000114226.8
ENSMUST00000204511.3
ENSMUST00000114225.8
ENSMUST00000114224.8
ENSMUST00000114222.4
guanine nucleotide binding protein (G protein), gamma 12
chr19_-_29783389 0.65 ENSMUST00000177155.8
RIKEN cDNA 9930021J03 gene
chr6_-_126143678 0.61 ENSMUST00000112244.8
neurotrophin 3
chr17_-_88372671 0.59 ENSMUST00000235112.2
ENSMUST00000005504.15
F-box protein 11
chr11_-_100830183 0.59 ENSMUST00000092671.12
ENSMUST00000103114.8
signal transducer and activator of transcription 3
chr2_+_24257576 0.58 ENSMUST00000140547.2
ENSMUST00000102942.8
pleckstrin and Sec7 domain containing 4
chr7_-_115637970 0.58 ENSMUST00000166877.8
SRY (sex determining region Y)-box 6
chr5_+_147367237 0.57 ENSMUST00000176600.8
PAN3 poly(A) specific ribonuclease subunit
chr14_+_49303952 0.56 ENSMUST00000037473.6
ENSMUST00000228238.2
adaptor-related protein complex 5, mu 1 subunit
chr5_-_4154681 0.56 ENSMUST00000001507.5
cytochrome P450, family 51
chr3_+_97920819 0.55 ENSMUST00000079812.8
notch 2
chr2_+_153583194 0.53 ENSMUST00000028981.9
microtubule-associated protein, RP/EB family, member 1
chr19_-_6107766 0.51 ENSMUST00000235520.2
ENSMUST00000007482.8
mitochondrial ribosomal protein L49
chr2_-_12306722 0.51 ENSMUST00000028106.11
integrin alpha 8
chrM_+_3906 0.47 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr15_+_102378966 0.46 ENSMUST00000077037.13
ENSMUST00000229102.2
ENSMUST00000229618.2
ENSMUST00000229275.2
ENSMUST00000231089.2
ENSMUST00000229802.2
ENSMUST00000229854.2
ENSMUST00000108838.5
poly(rC) binding protein 2
chr3_-_37286714 0.45 ENSMUST00000161015.2
ENSMUST00000029273.8
interleukin 21
chr16_+_11140740 0.43 ENSMUST00000180792.8
sorting nexin 29
chr11_+_79883885 0.43 ENSMUST00000163272.2
ENSMUST00000017692.15
SUZ12 polycomb repressive complex 2 subunit
chr12_+_9624437 0.43 ENSMUST00000057021.9
odd-skipped related transcription factor 1
chr6_-_99243455 0.41 ENSMUST00000113326.9
forkhead box P1
chr10_+_67815395 0.41 ENSMUST00000118160.8
rhotekin 2
chr1_-_106641940 0.39 ENSMUST00000112751.2
B cell leukemia/lymphoma 2
chr5_+_16758777 0.39 ENSMUST00000030683.8
hepatocyte growth factor
chr1_+_59802543 0.35 ENSMUST00000087435.7
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr9_+_51958453 0.35 ENSMUST00000163153.9
radixin
chr4_+_125997734 0.33 ENSMUST00000116286.9
ENSMUST00000094761.11
serine/threonine kinase 40
chr8_-_86281946 0.32 ENSMUST00000034138.7
DnaJ heat shock protein family (Hsp40) member A2
chr3_-_9675130 0.32 ENSMUST00000041124.13
zinc finger protein 704
chr2_+_48704121 0.30 ENSMUST00000063886.4
activin receptor IIA
chr10_+_42637479 0.29 ENSMUST00000019937.5
SEC63-like (S. cerevisiae)
chr6_+_134807097 0.29 ENSMUST00000046303.12
cAMP responsive element binding protein-like 2
chr4_-_133695204 0.26 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr3_-_41037427 0.25 ENSMUST00000058578.8
progesterone receptor membrane component 2
chr4_+_89055359 0.25 ENSMUST00000058030.10
methylthioadenosine phosphorylase
chr1_-_161616031 0.24 ENSMUST00000000834.4
Fas ligand (TNF superfamily, member 6)
chr6_-_86503178 0.21 ENSMUST00000053015.7
poly(rC) binding protein 1
chr5_+_123280250 0.18 ENSMUST00000174836.8
ENSMUST00000163030.9
SET domain containing 1B
chr8_+_108020092 0.18 ENSMUST00000169453.8
nuclear factor of activated T cells 5
chrX_+_159945740 0.17 ENSMUST00000074802.12
ENSMUST00000019101.11
ENSMUST00000112345.8
Scm polycomb group protein like 2
chr10_-_18891095 0.17 ENSMUST00000019997.11
tumor necrosis factor, alpha-induced protein 3
chr2_+_173501553 0.17 ENSMUST00000029024.10
ENSMUST00000109110.4
RAB22A, member RAS oncogene family
chr8_+_107662352 0.17 ENSMUST00000212524.2
ENSMUST00000047425.5
syntrophin, basic 2
chr2_+_118731860 0.16 ENSMUST00000036578.7
bromo adjacent homology domain containing 1
chr5_+_122296322 0.16 ENSMUST00000102528.11
ENSMUST00000086294.11
protein phosphatase 1 catalytic subunit gamma
chr1_+_74545203 0.14 ENSMUST00000087215.7
CCR4-NOT transcription complex, subunit 9
chr9_-_70564403 0.14 ENSMUST00000213380.2
ENSMUST00000049031.6
MINDY lysine 48 deubiquitinase 2
chr4_+_122889737 0.14 ENSMUST00000106252.9
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
chr14_+_30741082 0.13 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chr7_+_120276801 0.13 ENSMUST00000208454.2
ENSMUST00000060175.8
modulator of smoothened
chr4_-_70453140 0.12 ENSMUST00000107359.9
multiple EGF-like-domains 9
chr18_+_35904541 0.11 ENSMUST00000170693.9
ENSMUST00000237984.2
ENSMUST00000167406.2
ubiquitin-conjugating enzyme E2D 2A
chr11_-_100541519 0.10 ENSMUST00000103119.10
zinc finger protein 385C
chr5_-_64126194 0.09 ENSMUST00000154169.4
RELT-like 1
chr6_+_71470833 0.09 ENSMUST00000064637.11
ENSMUST00000114178.8
ring finger protein 103
chr3_+_151916059 0.09 ENSMUST00000166984.8
far upstream element (FUSE) binding protein 1
chr10_+_7556948 0.08 ENSMUST00000165952.9
large tumor suppressor
chr5_+_53713137 0.07 ENSMUST00000087360.9
recombination signal binding protein for immunoglobulin kappa J region
chr17_+_29251602 0.07 ENSMUST00000130216.3
serine and arginine-rich splicing factor 3
chr5_-_92496730 0.06 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr4_-_138641225 0.06 ENSMUST00000097830.4
OTU domain containing 3
chr4_-_141518202 0.04 ENSMUST00000038014.11
ENSMUST00000153880.2
DnaJ heat shock protein family (Hsp40) member C16
chr17_+_26934617 0.04 ENSMUST00000062519.14
ENSMUST00000144221.2
ENSMUST00000142539.8
ENSMUST00000151681.2
CREB3 regulatory factor
chr19_+_7394951 0.03 ENSMUST00000159348.3
RIKEN cDNA 2700081O15 gene
chr13_-_64300964 0.03 ENSMUST00000059817.12
ENSMUST00000117241.2
zinc finger protein 367
chr3_-_9898713 0.03 ENSMUST00000161949.8
phosphoprotein associated with glycosphingolipid microdomains 1
chr9_-_123461593 0.03 ENSMUST00000026273.11
solute carrier family 6 (neurotransmitter transporter), member 20B
chr8_-_35432783 0.02 ENSMUST00000033929.6
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
1.0 6.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 3.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7 2.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.7 2.9 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.7 3.4 GO:0072363 regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.6 2.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.5 2.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.5 1.6 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.5 1.6 GO:0002649 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.5 1.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 4.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 0.4 GO:0061227 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.4 1.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 1.7 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.4 3.9 GO:0036302 atrioventricular canal development(GO:0036302)
0.4 0.4 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.3 1.3 GO:2000795 lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 2.9 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 2.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.3 0.8 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.2 1.4 GO:0032902 nerve growth factor production(GO:0032902)
0.2 2.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 2.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 2.9 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 0.8 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.2 0.8 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.2 3.9 GO:0060736 prostate gland growth(GO:0060736)
0.2 2.6 GO:0072189 ureter development(GO:0072189)
0.2 4.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 3.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.7 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.8 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.5 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 2.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.6 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.5 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.3 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.8 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.4 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.6 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 1.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.5 GO:0046688 response to copper ion(GO:0046688)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.2 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.2 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 2.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.1 GO:0010225 response to UV-C(GO:0010225)
0.1 2.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.9 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.6 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 1.4 GO:0014002 astrocyte development(GO:0014002)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 2.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 3.9 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.8 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 2.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)
0.0 4.8 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 1.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.7 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.7 2.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.6 2.4 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.5 1.6 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.3 3.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.3 0.8 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.2 1.2 GO:0034657 GID complex(GO:0034657)
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0001739 sex chromatin(GO:0001739)
0.1 6.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0031251 PAN complex(GO:0031251)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 7.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 6.1 GO:0016607 nuclear speck(GO:0016607)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 1.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 8.4 GO:0005912 adherens junction(GO:0005912)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0098808 mRNA cap binding(GO:0098808)
0.7 4.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 2.9 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.7 4.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 2.5 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.5 1.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 2.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 1.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 2.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 2.9 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.3 0.8 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 3.4 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 5.5 GO:0005112 Notch binding(GO:0005112)
0.1 0.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 5.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.1 2.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.6 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.0 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 6.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 3.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 8.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 5.1 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0032451 demethylase activity(GO:0032451)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 6.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 3.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.1 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 7.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 5.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 4.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 4.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 5.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK