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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for AGUGCUU

Z-value: 0.66

Motif logo

miRNA associated with seed AGUGCUU

NamemiRBASE accession
MIMAT0003376

Activity profile of AGUGCUU motif

Sorted Z-values of AGUGCUU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCUU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_55033113 5.29 ENSMUST00000038926.13
bromodomain adjacent to zinc finger domain 1A
chr11_-_117859997 4.40 ENSMUST00000054002.4
suppressor of cytokine signaling 3
chr17_-_32074754 4.11 ENSMUST00000024839.6
salt inducible kinase 1
chr5_-_136596299 4.03 ENSMUST00000004097.16
cut-like homeobox 1
chr2_+_119156265 3.78 ENSMUST00000102517.4
delta like canonical Notch ligand 4
chr19_+_41471067 3.76 ENSMUST00000067795.13
ligand dependent nuclear receptor corepressor
chr8_+_84682136 3.65 ENSMUST00000005607.9
anti-silencing function 1B histone chaperone
chr16_+_42727926 3.33 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr5_-_21156766 3.28 ENSMUST00000036489.10
round spermatid basic protein 1-like
chr1_-_13660027 3.25 ENSMUST00000027068.11
translocating chain-associating membrane protein 1
chr9_+_72439496 3.18 ENSMUST00000163401.9
ENSMUST00000093820.10
regulatory factor X, 7
chr2_-_104647041 3.06 ENSMUST00000117237.2
ENSMUST00000231375.2
glutamine and serine rich 1
chr9_+_30941924 2.93 ENSMUST00000216649.2
ENSMUST00000115222.10
zinc finger and BTB domain containing 44
chr15_+_102314809 2.92 ENSMUST00000001326.7
trans-acting transcription factor 1
chr11_-_117671436 2.87 ENSMUST00000026659.10
ENSMUST00000127227.2
transmembrane channel-like gene family 6
chr1_-_69724939 2.82 ENSMUST00000027146.9
IKAROS family zinc finger 2
chr11_-_103158190 2.79 ENSMUST00000021324.3
mitogen-activated protein kinase kinase kinase 14
chr18_+_84106188 2.75 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr12_-_79343040 2.69 ENSMUST00000218377.2
ENSMUST00000021547.8
zinc finger, FYVE domain containing 26
chr6_+_38410848 2.66 ENSMUST00000160583.8
ubinuclein 2
chr8_-_41586713 2.62 ENSMUST00000155055.2
ENSMUST00000059115.13
ENSMUST00000145860.2
mitochondrial tumor suppressor 1
chr7_-_115637970 2.57 ENSMUST00000166877.8
SRY (sex determining region Y)-box 6
chr18_-_10182007 2.50 ENSMUST00000067947.7
Rho-associated coiled-coil containing protein kinase 1
chr10_-_12839995 2.45 ENSMUST00000219727.2
ENSMUST00000163425.9
ENSMUST00000042861.7
ENSMUST00000218685.2
syntaxin 11
chr16_+_65612083 2.40 ENSMUST00000168064.3
vestigial like family member 3
chr1_-_82269137 2.38 ENSMUST00000069799.3
insulin receptor substrate 1
chr14_+_32321341 2.38 ENSMUST00000187377.7
ENSMUST00000189022.8
ENSMUST00000186452.7
paired related homeobox protein-like 1
chr10_+_70080913 2.35 ENSMUST00000046807.7
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr12_+_71062733 2.28 ENSMUST00000046305.12
AT rich interactive domain 4A (RBP1-like)
chr4_+_135899678 2.26 ENSMUST00000061721.6
E2F transcription factor 2
chr14_+_34395845 2.25 ENSMUST00000048263.14
WAPL cohesin release factor
chr1_-_151304191 2.24 ENSMUST00000064771.12
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr3_-_100396635 2.13 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr9_+_74769166 2.10 ENSMUST00000056006.11
one cut domain, family member 1
chr5_-_9047324 2.09 ENSMUST00000003720.5
carnitine O-octanoyltransferase
chr8_-_58106057 2.00 ENSMUST00000034021.12
polypeptide N-acetylgalactosaminyltransferase 7
chr18_+_73706115 2.00 ENSMUST00000091852.5
mex3 RNA binding family member C
chr6_+_91955820 2.00 ENSMUST00000089334.9
FYVE, RhoGEF and PH domain containing 5
chr9_+_118435755 1.98 ENSMUST00000044165.14
integrin alpha 9
chr1_-_171854818 1.98 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr9_-_44792575 1.96 ENSMUST00000114689.8
ENSMUST00000002095.11
ENSMUST00000128768.3
lysine (K)-specific methyltransferase 2A
chr7_+_89779564 1.94 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chrX_-_50294652 1.93 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr4_-_129121676 1.91 ENSMUST00000106051.8
expressed sequence C77080
chr18_+_89215543 1.87 ENSMUST00000037142.13
CD226 antigen
chr12_-_70033732 1.83 ENSMUST00000021467.8
salvador family WW domain containing 1
chr4_+_97665843 1.82 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chrX_+_13147209 1.81 ENSMUST00000000804.7
DEAD box helicase 3, X-linked
chr9_-_114393406 1.81 ENSMUST00000111816.3
tripartite motif-containing 71
chr9_-_116004265 1.81 ENSMUST00000061101.12
transforming growth factor, beta receptor II
chr5_-_143717970 1.78 ENSMUST00000053287.6
ubiquitin specific peptidase 42
chr15_+_80595486 1.74 ENSMUST00000067689.9
trinucleotide repeat containing 6b
chr3_-_105708632 1.70 ENSMUST00000090678.11
RAS-related protein 1a
chr2_-_157046386 1.67 ENSMUST00000029170.8
RB transcriptional corepressor like 1
chr2_-_62242562 1.65 ENSMUST00000047812.8
dipeptidylpeptidase 4
chr4_+_124696336 1.63 ENSMUST00000138807.8
ENSMUST00000030723.3
metal response element binding transcription factor 1
chr15_+_6737853 1.62 ENSMUST00000061656.8
RPTOR independent companion of MTOR, complex 2
chr4_-_43562397 1.60 ENSMUST00000030187.14
talin 1
chr10_+_43354807 1.59 ENSMUST00000167488.9
BEN domain containing 3
chr9_+_51958453 1.57 ENSMUST00000163153.9
radixin
chr2_-_63928339 1.56 ENSMUST00000131615.9
fidgetin
chr4_+_106173384 1.54 ENSMUST00000165709.8
ENSMUST00000094933.5
ubiquitin specific peptidase 24
chr1_-_181039509 1.53 ENSMUST00000162819.9
ENSMUST00000237749.2
WD repeat domain 26
chr11_+_68322945 1.49 ENSMUST00000021283.8
phosphoinositide-3-kinase regulatory subunit 5
chr10_+_128212953 1.48 ENSMUST00000014642.10
ankyrin repeat domain 52
chr11_-_51891259 1.43 ENSMUST00000020657.13
ubiquitin-conjugating enzyme E2B
chr12_-_87346479 1.42 ENSMUST00000125733.8
isthmin 2
chr5_+_147367237 1.37 ENSMUST00000176600.8
PAN3 poly(A) specific ribonuclease subunit
chr12_-_98703664 1.37 ENSMUST00000170188.8
protein tyrosine phosphatase, non-receptor type 21
chr7_-_144493560 1.34 ENSMUST00000093962.5
cyclin D1
chrX_-_161671421 1.33 ENSMUST00000033723.4
synapse associated protein 1
chr5_-_96309849 1.29 ENSMUST00000155901.8
CCR4-NOT transcription complex, subunit 6-like
chr5_+_97145533 1.29 ENSMUST00000112974.6
ENSMUST00000035635.10
BMP2 inducible kinase
chr5_+_128677863 1.29 ENSMUST00000117102.4
frizzled class receptor 10
chr5_-_72661776 1.28 ENSMUST00000175766.8
ENSMUST00000177290.8
ENSMUST00000176974.2
ENSMUST00000167460.9
corin, serine peptidase
chr11_-_72302520 1.26 ENSMUST00000108500.8
ENSMUST00000050226.7
smoothelin-like 2
chr4_-_53159885 1.26 ENSMUST00000030010.4
ATP-binding cassette, sub-family A (ABC1), member 1
chr14_-_104705420 1.25 ENSMUST00000053016.10
POU domain, class 4, transcription factor 1
chr10_-_116417333 1.22 ENSMUST00000218744.2
ENSMUST00000105267.8
ENSMUST00000105265.8
ENSMUST00000167706.8
ENSMUST00000168036.8
ENSMUST00000169921.8
ENSMUST00000020374.6
CCR4-NOT transcription complex, subunit 2
chr10_+_34359395 1.22 ENSMUST00000019913.15
fyn-related kinase
chr6_-_84570890 1.20 ENSMUST00000168003.9
cytochrome P450, family 26, subfamily b, polypeptide 1
chr11_-_49603501 1.19 ENSMUST00000020624.7
ENSMUST00000145353.8
CCR4-NOT transcription complex, subunit 6
chr16_-_16377982 1.19 ENSMUST00000161861.8
FYVE, RhoGEF and PH domain containing 4
chr11_+_79883885 1.16 ENSMUST00000163272.2
ENSMUST00000017692.15
SUZ12 polycomb repressive complex 2 subunit
chr3_+_65435825 1.15 ENSMUST00000047906.10
TCDD-inducible poly(ADP-ribose) polymerase
chr4_+_141028539 1.14 ENSMUST00000006614.3
Eph receptor A2
chr3_+_16237371 1.13 ENSMUST00000108345.9
ENSMUST00000191774.6
ENSMUST00000108346.5
YTH N6-methyladenosine RNA binding protein 3
chr3_-_142587678 1.12 ENSMUST00000043812.15
protein kinase N2
chr10_+_69932930 1.07 ENSMUST00000147545.8
coiled-coil domain containing 6
chr19_-_47680528 1.06 ENSMUST00000026045.14
ENSMUST00000086923.6
collagen, type XVII, alpha 1
chr7_+_122723365 1.04 ENSMUST00000205514.2
ENSMUST00000094053.7
trinucleotide repeat containing 6a
chr18_+_32296126 1.04 ENSMUST00000096575.5
mitogen-activated protein kinase kinase kinase 2
chr12_-_69245191 1.03 ENSMUST00000021356.6
dynein, axonemal assembly factor 2
chr15_+_95688712 1.03 ENSMUST00000071874.8
anoctamin 6
chr12_+_86407886 1.03 ENSMUST00000116402.10
estrogen related receptor, beta
chr15_-_57998443 1.01 ENSMUST00000038194.5
ATPase family, AAA domain containing 2
chr1_+_160733942 1.01 ENSMUST00000161609.8
RING CCCH (C3H) domains 1
chr15_+_99476935 1.01 ENSMUST00000023752.6
aquaporin 2
chr19_+_18648088 1.00 ENSMUST00000025632.11
carnosine N-methyltransferase 1
chr5_+_88868714 1.00 ENSMUST00000113229.8
ENSMUST00000006424.8
MOB kinase activator 1B
chr14_+_28226697 0.99 ENSMUST00000063465.12
wingless-type MMTV integration site family, member 5A
chr11_-_86248395 0.97 ENSMUST00000043624.9
mediator complex subunit 13
chr6_-_127128007 0.96 ENSMUST00000000188.12
cyclin D2
chrX_+_104807868 0.96 ENSMUST00000033581.4
fibroblast growth factor 16
chr18_-_61533434 0.94 ENSMUST00000063307.6
ENSMUST00000075299.13
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr16_-_4377640 0.94 ENSMUST00000005862.9
transcription factor AP4
chr10_-_7656635 0.93 ENSMUST00000124838.2
ENSMUST00000039763.14
glycoprotein integral membrane 1
chr14_+_30201569 0.92 ENSMUST00000022535.9
ENSMUST00000223658.2
decapping mRNA 1A
chr2_-_150531280 0.92 ENSMUST00000046095.10
visual system homeobox 1
chr14_+_36776775 0.91 ENSMUST00000120052.2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr13_-_34529157 0.91 ENSMUST00000040336.12
solute carrier family 22, member 23
chr1_+_133291302 0.91 ENSMUST00000135222.9
ethanolamine kinase 2
chr13_-_56283331 0.91 ENSMUST00000045788.9
ENSMUST00000016081.13
macroH2A.1 histone
chr13_+_43551851 0.88 ENSMUST00000071926.5
ENSMUST00000222499.2
nucleolar protein 7
chr18_+_35962832 0.88 ENSMUST00000060722.8
CXXC finger 5
chr15_+_12205095 0.87 ENSMUST00000038172.16
myotubularin related protein 12
chr4_-_133615075 0.86 ENSMUST00000003741.16
ENSMUST00000105894.11
ribosomal protein S6 kinase polypeptide 1
chr10_-_128727542 0.86 ENSMUST00000026408.7
growth differentiation factor 11
chr16_+_35803674 0.85 ENSMUST00000004054.13
karyopherin (importin) alpha 1
chr13_-_25015392 0.84 ENSMUST00000006900.7
acyl-CoA thioesterase 13
chr13_-_38178059 0.84 ENSMUST00000225319.2
ENSMUST00000225246.2
ENSMUST00000021864.8
signal sequence receptor, alpha
chr1_-_152642032 0.83 ENSMUST00000111859.8
ral guanine nucleotide dissociation stimulator,-like 1
chr14_-_21102487 0.83 ENSMUST00000154460.8
ENSMUST00000130291.8
adaptor-related protein complex 3, mu 1 subunit
chr2_+_131028861 0.83 ENSMUST00000028804.15
ENSMUST00000079857.9
cell division cycle 25B
chr3_+_88857929 0.82 ENSMUST00000186583.7
ASH1 like histone lysine methyltransferase
chr15_+_37233280 0.79 ENSMUST00000161405.8
ENSMUST00000022895.15
ENSMUST00000161532.2
grainyhead like transcription factor 2
chr5_-_67585137 0.79 ENSMUST00000169190.5
BEN domain containing 4
chr1_+_93406686 0.78 ENSMUST00000027495.15
ENSMUST00000136182.8
ENSMUST00000131175.9
ENSMUST00000153826.8
ENSMUST00000129211.8
ENSMUST00000179353.8
ENSMUST00000172165.8
ENSMUST00000168776.8
septin 2
septin 2
chr7_-_127494750 0.77 ENSMUST00000033074.8
vitamin K epoxide reductase complex, subunit 1
chr11_-_46280336 0.75 ENSMUST00000020664.13
IL2 inducible T cell kinase
chr12_+_70499869 0.74 ENSMUST00000021471.13
thioredoxin-related transmembrane protein 1
chr11_-_95896721 0.74 ENSMUST00000013559.3
insulin-like growth factor 2 mRNA binding protein 1
chr11_-_4544751 0.74 ENSMUST00000109943.10
myotubularin related protein 3
chr15_-_50753061 0.74 ENSMUST00000165201.9
ENSMUST00000184458.8
transcriptional repressor GATA binding 1
chr11_+_4207557 0.73 ENSMUST00000066283.12
leukemia inhibitory factor
chr18_+_70701260 0.72 ENSMUST00000074058.11
ENSMUST00000114946.4
methyl-CpG binding domain protein 2
chr6_-_37419030 0.71 ENSMUST00000041093.6
cAMP responsive element binding protein 3-like 2
chr8_-_86281946 0.69 ENSMUST00000034138.7
DnaJ heat shock protein family (Hsp40) member A2
chr8_+_47192767 0.67 ENSMUST00000034041.9
ENSMUST00000208507.2
ENSMUST00000207105.2
interferon regulatory factor 2
chr6_+_72391283 0.66 ENSMUST00000065906.9
gamma-glutamyl carboxylase
chr2_-_33358513 0.65 ENSMUST00000113156.2
ENSMUST00000028125.12
ENSMUST00000126442.2
zinc finger and BTB domain containing 43
chr7_-_74204222 0.64 ENSMUST00000134539.2
ENSMUST00000026897.14
ENSMUST00000098371.9
solute carrier organic anion transporter family, member 3a1
chr4_-_118148537 0.62 ENSMUST00000049074.13
protein tyrosine phosphatase, receptor type, F
chr14_-_8457069 0.60 ENSMUST00000022257.4
ataxin 7
chr9_-_101128976 0.60 ENSMUST00000075941.12
protein phosphatase 2, regulatory subunit B'', alpha
chr3_+_90161470 0.59 ENSMUST00000029545.15
CREB regulated transcription coactivator 2
chr10_+_93476903 0.59 ENSMUST00000020204.5
netrin 4
chr12_-_85386120 0.59 ENSMUST00000040992.8
NIMA (never in mitosis gene a)-related expressed kinase 9
chr1_+_138891447 0.59 ENSMUST00000168527.8
DENN/MADD domain containing 1B
chr9_-_104140099 0.58 ENSMUST00000035170.13
DnaJ heat shock protein family (Hsp40) member C13
chr1_+_6284823 0.58 ENSMUST00000027040.13
RB1-inducible coiled-coil 1
chr2_+_72306503 0.58 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chr11_+_75422516 0.57 ENSMUST00000149727.8
ENSMUST00000108433.8
ENSMUST00000042561.14
ENSMUST00000143035.8
solute carrier family 43, member 2
chr1_+_139349912 0.55 ENSMUST00000200243.5
ENSMUST00000039867.10
zinc finger and BTB domain containing 41
chr8_+_88999031 0.55 ENSMUST00000169037.9
adenylate cyclase 7
chr2_+_173501553 0.55 ENSMUST00000029024.10
ENSMUST00000109110.4
RAB22A, member RAS oncogene family
chr6_+_134897364 0.55 ENSMUST00000067327.11
ENSMUST00000003115.9
cyclin-dependent kinase inhibitor 1B
chr5_-_140375010 0.55 ENSMUST00000031539.12
sorting nexin 8
chr7_+_79944198 0.54 ENSMUST00000163812.9
ENSMUST00000047558.14
ENSMUST00000174199.8
ENSMUST00000173824.8
ENSMUST00000174172.8
protein regulator of cytokinesis 1
chr13_+_55357585 0.53 ENSMUST00000224973.2
ENSMUST00000099490.3
nuclear receptor-binding SET-domain protein 1
chr19_-_28657477 0.53 ENSMUST00000162022.8
ENSMUST00000112612.9
GLIS family zinc finger 3
chr3_+_88439616 0.52 ENSMUST00000172699.2
mex3 RNA binding family member A
chr19_-_60569323 0.52 ENSMUST00000111460.5
ENSMUST00000166712.9
ENSMUST00000081790.15
CDK2 associated, cullin domain 1
chr15_-_93173032 0.52 ENSMUST00000057896.5
ENSMUST00000049484.13
ENSMUST00000230063.2
glucoside xylosyltransferase 1
chr7_+_132532841 0.51 ENSMUST00000106157.8
zinc finger, RAN-binding domain containing 1
chr2_+_68691778 0.49 ENSMUST00000028426.9
ceramide synthase 6
chr11_-_93859064 0.48 ENSMUST00000107844.3
ENSMUST00000170303.2
NME/NM23 nucleoside diphosphate kinase 1
predicted gene 20390
chr3_+_32490300 0.48 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr1_+_38037086 0.48 ENSMUST00000027252.8
eukaryotic translation initiation factor 5B
chr7_-_120673761 0.47 ENSMUST00000047194.4
immunoglobulin superfamily, member 6
chr6_-_28261881 0.46 ENSMUST00000115320.8
ENSMUST00000123098.8
ENSMUST00000115321.9
ENSMUST00000155494.2
zinc finger protein 800
chr7_+_51528788 0.46 ENSMUST00000107591.9
growth arrest specific 2
chr13_-_96678987 0.44 ENSMUST00000022172.12
polymerase (DNA directed), kappa
chr7_+_96730763 0.43 ENSMUST00000004622.7
growth factor receptor bound protein 2-associated protein 2
chr13_-_45155616 0.43 ENSMUST00000072329.15
dystrobrevin binding protein 1
chr10_+_128295159 0.42 ENSMUST00000026433.9
ENSMUST00000099131.11
ENSMUST00000105235.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr8_+_11808349 0.40 ENSMUST00000074856.13
ENSMUST00000098938.9
Rho guanine nucleotide exchange factor (GEF7)
chr9_+_58730695 0.40 ENSMUST00000034889.10
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr16_-_19525122 0.40 ENSMUST00000081880.7
lysosomal-associated membrane protein 3
chr12_-_54909568 0.40 ENSMUST00000078124.8
cofilin 2, muscle
chr10_+_4561974 0.39 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr9_-_42383494 0.38 ENSMUST00000128959.8
ENSMUST00000066148.12
ENSMUST00000138506.8
tubulin folding cofactor E-like
chr6_-_83418656 0.38 ENSMUST00000089622.11
tet methylcytosine dioxygenase 3
chr6_+_85400868 0.37 ENSMUST00000089578.9
notochord homeobox
chr6_-_83752749 0.37 ENSMUST00000014892.8
testis expressed gene 261
chr1_-_157240138 0.36 ENSMUST00000078308.13
RAS protein activator like 2
chr2_+_75662511 0.36 ENSMUST00000047232.14
ENSMUST00000111952.9
alkylglycerone phosphate synthase
chr13_+_14238361 0.36 ENSMUST00000129488.8
ENSMUST00000110536.8
ENSMUST00000110534.8
ENSMUST00000039538.15
ENSMUST00000110533.2
AT rich interactive domain 4B (RBP1-like)
chr7_+_116980173 0.35 ENSMUST00000032892.7
xylosyltransferase 1
chr11_+_70453806 0.35 ENSMUST00000079244.12
ENSMUST00000102558.11
misshapen-like kinase 1 (zebrafish)
chr2_-_34262012 0.34 ENSMUST00000113132.9
ENSMUST00000040638.15
pre B cell leukemia homeobox 3
chr2_-_19002932 0.34 ENSMUST00000006912.12
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr19_+_43678109 0.34 ENSMUST00000081079.6
ectonucleoside triphosphate diphosphohydrolase 7
chr11_-_97078698 0.33 ENSMUST00000001479.5
karyopherin (importin) beta 1
chr17_+_25407352 0.33 ENSMUST00000039734.12
unkempt family like zinc finger
chr4_-_151142351 0.32 ENSMUST00000030797.4
vesicle-associated membrane protein 3
chr15_+_40518414 0.32 ENSMUST00000053467.6
zinc finger protein, multitype 2
chr2_-_131871725 0.31 ENSMUST00000028814.15
Ras association (RalGDS/AF-6) domain family member 2
chr3_-_87081939 0.30 ENSMUST00000159976.8
ENSMUST00000107618.9
kirre like nephrin family adhesion molecule 1
chr10_+_93983844 0.29 ENSMUST00000105290.9
nuclear receptor subfamily 2, group C, member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.0 2.9 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.9 5.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.7 3.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.6 1.8 GO:0002661 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.5 4.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.5 2.0 GO:2001025 positive regulation of response to drug(GO:2001025)
0.5 1.4 GO:0033128 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.5 2.3 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 2.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.4 5.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 2.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.4 2.4 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.4 1.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.4 2.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.4 4.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.4 1.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.3 1.0 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.3 1.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 3.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.6 GO:0036343 psychomotor behavior(GO:0036343)
0.3 1.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 1.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.3 1.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986) sensory system development(GO:0048880)
0.3 1.9 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 1.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 4.6 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 2.6 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.3 0.8 GO:1903699 tarsal gland development(GO:1903699)
0.3 1.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 0.8 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.0 GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.2 0.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 1.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.2 1.6 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 1.2 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.6 GO:0061723 glycophagy(GO:0061723)
0.2 1.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 2.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.2 1.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.6 GO:0097494 regulation of vesicle size(GO:0097494)
0.2 1.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.5 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.5 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 0.9 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 2.4 GO:0021559 trigeminal nerve development(GO:0021559)
0.1 1.0 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 1.2 GO:0030035 microspike assembly(GO:0030035)
0.1 0.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 2.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 1.9 GO:0072189 ureter development(GO:0072189)
0.1 0.8 GO:0007144 female meiosis I(GO:0007144)
0.1 4.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.9 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.4 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.1 GO:0072179 nephric duct formation(GO:0072179) mesonephric duct formation(GO:0072181)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.4 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1 0.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.4 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 2.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:1990428 miRNA transport(GO:1990428)
0.1 1.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.5 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.5 GO:1904706 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 2.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 1.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 2.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 2.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.1 GO:0061157 mRNA destabilization(GO:0061157)
0.0 2.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.6 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.6 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.6 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 4.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.9 GO:0021511 spinal cord patterning(GO:0021511)
0.0 3.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.3 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.3 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 1.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 2.0 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 1.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 3.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 1.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0042026 protein refolding(GO:0042026)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 1.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0008623 CHRAC(GO:0008623)
0.7 2.0 GO:0060187 cell pole(GO:0060187)
0.5 2.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.4 2.4 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 1.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.4 GO:0031251 PAN complex(GO:0031251)
0.3 1.6 GO:0071438 invadopodium membrane(GO:0071438)
0.2 2.3 GO:0008278 cohesin complex(GO:0008278)
0.2 1.4 GO:0033503 HULC complex(GO:0033503)
0.2 1.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.5 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 3.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.2 GO:0001739 sex chromatin(GO:0001739)
0.1 1.6 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 4.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.6 GO:0051286 cell tip(GO:0051286)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.0 7.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 2.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 4.3 GO:0030496 midbody(GO:0030496)
0.0 1.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 4.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 6.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 3.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.6 1.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 1.3 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 2.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 1.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 0.8 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.9 GO:0004103 choline kinase activity(GO:0004103)
0.2 1.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 5.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 2.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.2 2.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 1.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.8 GO:0035198 miRNA binding(GO:0035198)
0.2 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.6 GO:0000182 rDNA binding(GO:0000182)
0.1 1.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 3.9 GO:0005112 Notch binding(GO:0005112)
0.1 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 2.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 6.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.0 GO:0043236 laminin binding(GO:0043236)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 5.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 7.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.9 GO:0043027 protein serine/threonine/tyrosine kinase activity(GO:0004712) cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.8 GO:0001047 core promoter binding(GO:0001047)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 6.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 2.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 6.1 PID EPO PATHWAY EPO signaling pathway
0.1 1.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 4.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 4.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 3.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 1.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 4.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 4.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 2.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 4.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen