Project
PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap
Navigation
Downloads
Results for Ahr
Z-value: 3.61
Motif logo
Transcription factors associated with Ahr
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ahr | mm39_v1_chr12_-_35584968_35585059 | 0.01 | 9.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Ahr
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 89.3 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 10.7 | 63.9 | GO:0099538 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.2 | 59.8 | GO:0007268 | chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537) |
| 3.0 | 51.4 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 5.0 | 49.8 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 3.1 | 49.2 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.5 | 46.1 | GO:0008542 | visual learning(GO:0008542) |
| 5.7 | 45.7 | GO:0015820 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 1.8 | 44.3 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
| 14.4 | 43.1 | GO:0060466 | activation of meiosis involved in egg activation(GO:0060466) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 341.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 194.7 | GO:0016021 | integral component of membrane(GO:0016021) |
| 1.0 | 187.3 | GO:0043204 | perikaryon(GO:0043204) |
| 0.6 | 179.4 | GO:0099572 | postsynaptic specialization(GO:0099572) |
| 1.5 | 83.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 83.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.7 | 72.7 | GO:0034705 | potassium channel complex(GO:0034705) |
| 2.4 | 66.7 | GO:1902710 | GABA receptor complex(GO:1902710) |
| 0.4 | 64.0 | GO:0030426 | growth cone(GO:0030426) |
| 0.2 | 59.5 | GO:0043025 | neuronal cell body(GO:0043025) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 93.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 1.1 | 81.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.9 | 80.5 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.7 | 64.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 10.7 | 63.9 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.6 | 59.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 1.2 | 56.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 2.0 | 54.4 | GO:0031489 | myosin V binding(GO:0031489) |
| 1.9 | 54.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) |
| 9.4 | 47.2 | GO:0099609 | microtubule lateral binding(GO:0099609) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 88.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 70.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.7 | 67.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 2.5 | 42.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.9 | 40.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.2 | 37.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.7 | 28.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.4 | 28.5 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.4 | 27.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.6 | 26.6 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 125.8 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 1.4 | 87.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 2.8 | 66.7 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.3 | 61.4 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.5 | 60.8 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.4 | 55.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 2.6 | 53.8 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 1.6 | 51.3 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.5 | 51.1 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 2.2 | 50.5 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |