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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Aire

Z-value: 0.91

Motif logo

Transcription factors associated with Aire

Gene Symbol Gene ID Gene Info
ENSMUSG00000000731.16 Aire

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Airemm39_v1_chr10_-_77879414_778794450.019.1e-01Click!

Activity profile of Aire motif

Sorted Z-values of Aire motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Aire

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_-_60229164 25.92 ENSMUST00000166381.3
cerebellar degeneration related antigen 1
chr16_+_22877000 8.01 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
kininogen 1
chr3_+_82933383 7.20 ENSMUST00000029630.15
ENSMUST00000166581.4
fibrinogen alpha chain
chr15_+_10358611 5.85 ENSMUST00000110541.8
ENSMUST00000110542.8
alanine-glyoxylate aminotransferase 2
chr19_+_39275518 5.83 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr12_+_84098888 5.49 ENSMUST00000120927.8
ENSMUST00000021653.8
acyl-CoA thioesterase 3
chr15_+_10358643 5.00 ENSMUST00000022858.8
alanine-glyoxylate aminotransferase 2
chr16_-_22847808 4.83 ENSMUST00000115349.9
kininogen 2
chr16_-_22847829 4.54 ENSMUST00000100046.9
kininogen 2
chr5_+_130398261 4.06 ENSMUST00000086029.10
calneuron 1
chrM_+_7758 3.89 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr5_+_137979763 3.80 ENSMUST00000035390.7
alpha-2-glycoprotein 1, zinc
chr10_+_123099945 3.73 ENSMUST00000238972.2
ENSMUST00000050756.8
TAFA chemokine like family member 2
chrM_+_7779 3.56 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chrM_+_14138 3.53 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chrM_+_11735 3.49 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr5_+_8010445 3.47 ENSMUST00000115421.3
STEAP family member 4
chrM_+_9459 3.47 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr2_+_55325931 3.27 ENSMUST00000067101.10
potassium inwardly-rectifying channel, subfamily J, member 3
chr17_+_35455532 3.17 ENSMUST00000068261.9
ATPase, H+ transporting, lysosomal V1 subunit G2
chr8_+_47439916 3.13 ENSMUST00000039840.15
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr10_-_95678748 3.03 ENSMUST00000210336.2
predicted gene, 33543
chr15_+_10981833 2.98 ENSMUST00000070877.7
alpha-methylacyl-CoA racemase
chr10_-_95678786 2.98 ENSMUST00000211096.2
predicted gene, 33543
chr9_-_110818679 2.94 ENSMUST00000084922.6
ENSMUST00000199891.2
receptor transporter protein 3
chrM_-_14061 2.74 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr9_+_109645686 2.65 ENSMUST00000118732.4
serine peptidase inhibitor, Kazal type 8
chr10_+_33733706 2.61 ENSMUST00000218204.2
sulfotransferase family 3A, member 1
chr5_+_31079177 2.58 ENSMUST00000031053.15
ENSMUST00000202752.2
ketohexokinase
chr9_+_109645606 2.49 ENSMUST00000198988.5
serine peptidase inhibitor, Kazal type 8
chr18_+_37858753 2.45 ENSMUST00000066149.9
protocadherin gamma subfamily A, 8
chr7_-_84059170 2.44 ENSMUST00000208995.2
aryl hydrocarbon receptor nuclear translocator 2
chr4_+_115268821 2.38 ENSMUST00000094887.4
cytochrome P450, family 4, subfamily a, polypeptide 12B
chr7_-_45136235 2.27 ENSMUST00000210701.2
predicted gene 45808
chr17_-_59320257 2.27 ENSMUST00000174122.2
ENSMUST00000025065.12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr10_-_127587576 2.25 ENSMUST00000079692.6
G protein-coupled receptor 182
chr7_+_45546365 2.24 ENSMUST00000069772.16
ENSMUST00000210503.2
ENSMUST00000209350.2
transmembrane protein 143
chr7_-_126275529 2.21 ENSMUST00000106372.11
ENSMUST00000155419.3
ENSMUST00000106373.9
sulfotransferase family 1A, phenol-preferring, member 1
chr1_-_5140504 2.16 ENSMUST00000147158.2
ENSMUST00000118000.8
regulator of G-protein signaling 20
chr10_-_106959444 2.04 ENSMUST00000165067.9
acyl-CoA synthetase short-chain family member 3
chr3_+_107008343 1.98 ENSMUST00000197470.5
potassium voltage-gated channel, shaker-related subfamily, member 2
chrM_+_8603 1.93 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr19_+_46695889 1.92 ENSMUST00000003655.9
arsenite methyltransferase
chr7_-_127494750 1.92 ENSMUST00000033074.8
vitamin K epoxide reductase complex, subunit 1
chr5_-_84565218 1.90 ENSMUST00000113401.4
Eph receptor A5
chr2_-_134486039 1.87 ENSMUST00000038228.11
thioredoxin-related transmembrane protein 4
chr11_-_101308441 1.81 ENSMUST00000070395.9
alanyl-tRNA synthetase domain containing 1
chr6_+_126916956 1.79 ENSMUST00000201617.2
DNA segment, Chr 6, Wayne State University 163, expressed
chr11_-_49077864 1.74 ENSMUST00000153999.3
ENSMUST00000066531.13
butyrophilin-like 9
chr9_-_19163273 1.73 ENSMUST00000214019.2
ENSMUST00000214267.2
olfactory receptor 843
chr15_-_76809607 1.72 ENSMUST00000229865.2
ENSMUST00000229055.2
zinc finger protein 647
chr5_-_105491795 1.72 ENSMUST00000171587.2
guanylate binding protein 11
chr8_-_4267260 1.70 ENSMUST00000168386.9
proline rich 36
chr1_+_5658716 1.69 ENSMUST00000160777.8
ENSMUST00000239100.2
ENSMUST00000027038.11
opioid receptor, kappa 1
chr14_+_3575406 1.67 ENSMUST00000124353.2
ubiquitin-conjugating enzyme E2E 2
chr16_-_30152708 1.59 ENSMUST00000229503.2
ATPase type 13A3
chrM_+_7006 1.56 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr11_-_115518774 1.54 ENSMUST00000154623.2
ENSMUST00000106503.10
ENSMUST00000141614.3
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr2_-_134485936 1.51 ENSMUST00000110120.2
thioredoxin-related transmembrane protein 4
chr14_+_52964069 1.42 ENSMUST00000184883.2
T cell receptor alpha variable 6D-3
chr6_+_42222841 1.41 ENSMUST00000031897.8
glutathione S-transferase kappa 1
chr13_+_64309675 1.38 ENSMUST00000021929.10
hyaluronic acid binding protein 4
chrX_+_73171069 1.37 ENSMUST00000033771.11
ENSMUST00000101457.10
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
chr6_-_131655849 1.32 ENSMUST00000076756.3
taste receptor, type 2, member 106
chr9_-_49479791 1.32 ENSMUST00000194252.6
neural cell adhesion molecule 1
chr10_-_130116088 1.31 ENSMUST00000061571.5
neurogenic differentiation 4
chr8_-_4267131 1.27 ENSMUST00000175906.2
proline rich 36
chr14_+_53531798 1.26 ENSMUST00000103626.3
T cell receptor alpha variable 9N-4
chr8_-_4266912 1.26 ENSMUST00000177491.8
proline rich 36
chr15_+_89095724 1.25 ENSMUST00000227951.2
ENSMUST00000226221.2
ENSMUST00000238818.2
ENSMUST00000228284.2
protein phosphatase 6, regulatory subunit 2
chrX_-_63319428 1.21 ENSMUST00000156121.2
SLIT and NTRK-like family, member 4
chr3_-_89319088 1.21 ENSMUST00000107429.10
ENSMUST00000129308.9
ENSMUST00000107426.8
ENSMUST00000050398.11
ENSMUST00000162701.2
flavin adenine dinucleotide synthetase 1
chr7_-_12096691 1.19 ENSMUST00000086228.3
vomeronasal 1 receptor 84
chr6_+_91678630 1.18 ENSMUST00000205828.2
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr3_+_107008867 1.15 ENSMUST00000038695.6
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_-_134485999 1.13 ENSMUST00000110119.2
thioredoxin-related transmembrane protein 4
chr6_-_71376277 1.12 ENSMUST00000149415.2
required for meiotic nuclear division 5 homolog A
chr15_-_75793312 1.11 ENSMUST00000053918.9
pyrroline-5-carboxylate reductase-like
chr8_+_112370088 1.10 ENSMUST00000077791.8
ENSMUST00000211926.2
zinc finger protein 1
chr9_+_45924105 1.08 ENSMUST00000126865.8
SIK family kinase 3
chr17_+_21869545 1.02 ENSMUST00000232827.2
zinc finger protein 983
chr16_-_91415873 1.00 ENSMUST00000143058.2
ENSMUST00000049244.10
ENSMUST00000169982.2
ENSMUST00000133731.2
DnaJ heat shock protein family (Hsp40) member C28
chr15_-_98063493 0.99 ENSMUST00000143400.8
ankyrin repeat and SOCS box-containing 8
chr2_+_175125091 0.98 ENSMUST00000098998.4
predicted gene 14440
chr2_+_176123622 0.98 ENSMUST00000172025.2
zinc finger protein 968, pseudogene
chr6_-_131662707 0.97 ENSMUST00000072404.3
taste receptor, type 2, member 104
chr2_-_36975758 0.96 ENSMUST00000100145.2
olfactory receptor 361
chr1_+_44159106 0.96 ENSMUST00000114709.3
ENSMUST00000129068.2
basic, immunoglobulin-like variable motif containing
chr3_-_62414391 0.96 ENSMUST00000029336.6
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr3_+_89366425 0.96 ENSMUST00000029564.12
phosphomevalonate kinase
chr8_+_112370033 0.95 ENSMUST00000212072.2
zinc finger protein 1
chr5_-_124492734 0.95 ENSMUST00000031341.11
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr6_-_39787813 0.95 ENSMUST00000114797.2
ENSMUST00000031978.9
mitochondrial ribosomal protein S33
chr12_+_37292029 0.94 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr11_-_58461379 0.93 ENSMUST00000216758.2
olfactory receptor 224
chr14_-_57809008 0.92 ENSMUST00000022518.8
ENSMUST00000239099.2
EEF1A alpha lysine methyltransferase 1
chr3_+_94350622 0.90 ENSMUST00000029786.14
ENSMUST00000196143.2
mitochondrial ribosomal protein L9
chr6_+_126916919 0.89 ENSMUST00000032497.7
DNA segment, Chr 6, Wayne State University 163, expressed
chr9_+_45924120 0.88 ENSMUST00000120463.9
ENSMUST00000120247.8
SIK family kinase 3
chr16_-_55755208 0.88 ENSMUST00000121129.8
ENSMUST00000023270.14
centrosomal protein 97
chr2_+_87854404 0.86 ENSMUST00000217006.2
olfactory receptor 1161
chr1_-_171108754 0.84 ENSMUST00000073120.11
protoporphyrinogen oxidase
chr3_+_89622323 0.83 ENSMUST00000098924.9
adenosine deaminase, RNA-specific
chr5_+_24305577 0.83 ENSMUST00000030841.10
ENSMUST00000163409.5
kelch-like 7
chr12_+_69343450 0.83 ENSMUST00000021362.5
kelch domain containing 2
chr6_-_91492860 0.81 ENSMUST00000206476.2
ENSMUST00000032182.5
xeroderma pigmentosum, complementation group C
chr6_-_66656668 0.80 ENSMUST00000071414.2
vomeronasal 1 receptor 35
chr1_+_21438462 0.79 ENSMUST00000070223.6
KH domain containing 1C
chrX_-_77289527 0.78 ENSMUST00000114026.3
predicted gene 14743
chr18_+_36926929 0.74 ENSMUST00000001419.10
zinc finger, matrin type 2
chr11_+_97206542 0.71 ENSMUST00000019026.10
ENSMUST00000132168.2
mitochondrial ribosomal protein L45
chr17_+_18801989 0.70 ENSMUST00000165692.8
vomeronasal 2, receptor 96
chrX_+_77230380 0.70 ENSMUST00000088198.4
odorant binding protein IB
chr12_-_79030250 0.70 ENSMUST00000070174.14
transmembrane protein 229B
chr7_+_20505110 0.69 ENSMUST00000174538.2
vomeronasal 1 receptor 112
chr6_-_68968278 0.69 ENSMUST00000197966.2
immunoglobulin kappa variable 4-81
chr13_+_55593116 0.67 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
G protein-coupled receptor kinase 6
chr10_+_52234863 0.67 ENSMUST00000180473.2
predicted gene, 26741
chr8_-_85663976 0.66 ENSMUST00000109741.9
ENSMUST00000119820.2
microtubule associated serine/threonine kinase 1
chr14_+_55170152 0.65 ENSMUST00000037863.6
interleukin 25
chrX_+_135418748 0.64 ENSMUST00000113104.8
ENSMUST00000113105.3
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr19_-_5713728 0.64 ENSMUST00000169854.2
signal-induced proliferation associated gene 1
chr10_+_80662490 0.63 ENSMUST00000060987.15
ENSMUST00000177850.8
ENSMUST00000180036.8
ENSMUST00000179172.8
ornithine decarboxylase antizyme 1
chr16_-_36695166 0.61 ENSMUST00000075946.12
ELL associated factor 2
chr7_-_102507962 0.60 ENSMUST00000213481.2
ENSMUST00000209952.2
olfactory receptor 566
chr1_-_65225617 0.59 ENSMUST00000186222.7
ENSMUST00000169032.8
ENSMUST00000191459.2
ENSMUST00000188876.7
isocitrate dehydrogenase 1 (NADP+), soluble
chr7_+_6463510 0.57 ENSMUST00000056120.5
olfactory receptor 1336
chr7_-_47251120 0.56 ENSMUST00000176369.2
MAS-related GPR, member A3
chr8_+_65399831 0.55 ENSMUST00000026595.13
ENSMUST00000209852.2
ENSMUST00000079896.9
transmembrane protein 192
chr1_-_65225572 0.55 ENSMUST00000188109.7
isocitrate dehydrogenase 1 (NADP+), soluble
chr6_+_40941688 0.54 ENSMUST00000076638.7
RIKEN cDNA 1810009J06 gene
chr14_-_50521663 0.53 ENSMUST00000213701.2
olfactory receptor 732
chr13_-_105429514 0.51 ENSMUST00000224011.2
ring finger protein 180
chr7_-_19398930 0.51 ENSMUST00000055242.11
cleft lip and palate associated transmembrane protein 1
chr6_-_58449863 0.51 ENSMUST00000226390.2
vomeronasal 1 receptor 31
chr7_-_102774821 0.50 ENSMUST00000211075.3
ENSMUST00000215304.2
ENSMUST00000213281.2
olfactory receptor 586
chr9_+_104424466 0.50 ENSMUST00000098443.9
copine IV
chr7_+_19927635 0.47 ENSMUST00000168984.2
vomeronasal 1 receptor, 95
chr6_-_66614736 0.47 ENSMUST00000074381.6
vomeronasal 1 receptor 34
chr5_-_121798541 0.46 ENSMUST00000031412.12
ENSMUST00000111770.2
acyl-Coenzyme A dehydrogenase family, member 10
chr5_-_134589025 0.44 ENSMUST00000149604.5
syncytin a
chr7_+_6392535 0.43 ENSMUST00000207465.2
ENSMUST00000208338.2
zinc finger protein 28
chr1_+_21419819 0.43 ENSMUST00000088407.4
KH domain containing 1A
chr11_+_62349238 0.41 ENSMUST00000014389.6
phosphatidylinositol glycan anchor biosynthesis, class L
chr1_+_173877941 0.41 ENSMUST00000062665.4
olfactory receptor 432
chr15_-_76809590 0.41 ENSMUST00000230677.2
zinc finger protein 647
chr2_+_85420854 0.41 ENSMUST00000052307.5
olfactory receptor 998
chr17_+_18518361 0.41 ENSMUST00000231938.2
ENSMUST00000079206.8
ENSMUST00000231879.3
vomeronasal 2, receptor 93
chr17_+_20907770 0.40 ENSMUST00000061756.4
vomeronasal 1 receptor 226
chr2_-_150531280 0.40 ENSMUST00000046095.10
visual system homeobox 1
chr1_+_65225886 0.39 ENSMUST00000097707.5
phosphoinositide kinase, FYVE type zinc finger containing
chr15_-_98063441 0.39 ENSMUST00000123922.2
ankyrin repeat and SOCS box-containing 8
chr14_-_56448874 0.37 ENSMUST00000022757.5
granzyme F
chr14_-_52634836 0.34 ENSMUST00000214168.2
olfactory receptor 1511
chr6_+_56933451 0.34 ENSMUST00000096612.4
vomeronasal 1 receptor 4
chr4_+_63477018 0.34 ENSMUST00000077709.11
transmembrane protein 268
chr2_+_83554741 0.32 ENSMUST00000028499.11
integrin alpha V
chr17_-_21134625 0.30 ENSMUST00000077001.3
vomeronasal 1 receptor 232
chr13_-_27574822 0.30 ENSMUST00000102954.10
ENSMUST00000091678.3
prolactin family 2, subfamily b, member 1
chr2_+_172090412 0.28 ENSMUST00000038532.2
melanocortin 3 receptor
chr2_+_89804937 0.26 ENSMUST00000214630.2
ENSMUST00000111512.10
ENSMUST00000144710.3
ENSMUST00000216678.2
olfactory receptor 1260
chr9_+_108883907 0.25 ENSMUST00000154184.5
shisa family member 5
chr7_+_25966256 0.25 ENSMUST00000057123.7
vomeronasal 1 receptor, 184
chr11_+_48977495 0.25 ENSMUST00000152914.2
interferon gamma inducible protein 47
chr19_-_5713701 0.25 ENSMUST00000164304.9
ENSMUST00000237544.2
signal-induced proliferation associated gene 1
chr10_+_129263175 0.24 ENSMUST00000204529.3
olfactory receptor 786
chr19_-_5713648 0.22 ENSMUST00000080824.13
ENSMUST00000237874.2
ENSMUST00000071857.13
ENSMUST00000236464.2
signal-induced proliferation associated gene 1
chr14_+_21531494 0.22 ENSMUST00000182996.2
K(lysine) acetyltransferase 6B
chr3_+_92339886 0.21 ENSMUST00000067102.3
small proline-rich protein 2K
chrX_-_37665041 0.21 ENSMUST00000050083.6
ENSMUST00000115118.8
cullin 4B
chr7_+_107679062 0.21 ENSMUST00000213601.2
olfactory receptor 481
chr6_-_58412879 0.20 ENSMUST00000078890.5
vomeronasal 1 receptor 30
chr9_-_39405284 0.20 ENSMUST00000077757.7
ENSMUST00000215065.3
ENSMUST00000216316.3
olfactory receptor 44
chr2_-_111320501 0.19 ENSMUST00000099616.2
olfactory receptor 1290
chr9_-_39920878 0.19 ENSMUST00000216463.3
olfactory receptor 980
chr2_+_85519775 0.19 ENSMUST00000054868.2
olfactory receptor 1008
chr11_-_66943389 0.18 ENSMUST00000116363.2
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
chr7_-_103217838 0.17 ENSMUST00000214806.2
olfactory receptor 616
chr7_-_6491875 0.17 ENSMUST00000036357.7
ENSMUST00000220413.2
olfactory receptor 1347
chr10_+_3822667 0.16 ENSMUST00000136671.8
ENSMUST00000042438.13
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_40976413 0.16 ENSMUST00000166306.3
predicted gene 2663
chr7_+_6477087 0.16 ENSMUST00000056144.7
olfactory receptor 1346
chr1_+_65225834 0.15 ENSMUST00000081154.14
phosphoinositide kinase, FYVE type zinc finger containing
chr11_-_83177548 0.15 ENSMUST00000163961.3
schlafen 14
chr1_+_88128323 0.14 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr2_-_89159994 0.13 ENSMUST00000213860.2
ENSMUST00000215679.2
olfactory receptor 1232
chr5_-_108943211 0.12 ENSMUST00000004943.2
transmembrane p24 trafficking protein 11
chr12_-_36206626 0.10 ENSMUST00000220828.2
basic leucine zipper and W2 domains 2
chr7_+_104718676 0.09 ENSMUST00000098160.2
olfactory receptor 678
chr9_-_108140925 0.05 ENSMUST00000171412.7
ENSMUST00000195429.6
ENSMUST00000080435.9
dystroglycan 1
chr12_+_36207113 0.04 ENSMUST00000041640.5
ankyrin repeat and MYND domain containing 2
chr14_+_51351880 0.04 ENSMUST00000100645.5
epididymal protein 3B
chr9_+_38164715 0.03 ENSMUST00000093865.3
olfactory receptor 143
chr7_+_104963189 0.02 ENSMUST00000098153.3
olfactory receptor 689
chr11_-_96002784 0.02 ENSMUST00000097162.6
ENSMUST00000068686.13
calcium binding and coiled-coil domain 2
chrX_-_91059789 0.02 ENSMUST00000099471.3
ENSMUST00000072269.2
MAGE family member B1
chr2_-_89969539 0.00 ENSMUST00000099755.5
olfactory receptor 32

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853)
1.8 5.5 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
1.8 7.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 2.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.6 1.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 3.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.5 1.9 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.4 3.5 GO:0033762 response to glucagon(GO:0033762)
0.4 1.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.4 1.2 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.4 1.5 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.4 2.3 GO:0006742 NADP catabolic process(GO:0006742)
0.4 1.1 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 3.1 GO:0019695 choline metabolic process(GO:0019695)
0.3 3.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 1.7 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.3 1.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 3.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.3 5.1 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.3 1.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.3 0.8 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 0.8 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.3 17.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 1.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 3.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.2 7.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 9.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 4.8 GO:0051923 sulfation(GO:0051923)
0.2 1.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.0 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.2 5.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.8 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.2 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 1.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.6 GO:0009624 response to nematode(GO:0009624)
0.1 0.3 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.1 1.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.9 GO:0009404 toxin metabolic process(GO:0009404)
0.1 7.0 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 0.9 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 3.5 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 2.7 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 4.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.0 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 3.2 GO:0015992 proton transport(GO:0015992)
0.0 2.6 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 1.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 3.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.5 GO:0032288 myelin assembly(GO:0032288)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.2 GO:0005577 fibrinogen complex(GO:0005577)
0.4 7.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3 3.5 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 1.1 GO:0034657 GID complex(GO:0034657)
0.2 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.8 GO:0071942 XPC complex(GO:0071942)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 11.3 GO:0070469 respiratory chain(GO:0070469)
0.1 3.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:0034683 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 17.4 GO:0072562 blood microparticle(GO:0072562)
0.0 12.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 5.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.9 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
1.0 5.8 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.9 2.6 GO:0004454 ketohexokinase activity(GO:0004454)
0.6 1.9 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.6 1.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 2.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 3.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.4 3.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 2.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 1.2 GO:0005369 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.4 2.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 3.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 9.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 0.9 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.3 3.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.3 1.7 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 0.8 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.3 5.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 2.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.2 1.7 GO:0004985 opioid receptor activity(GO:0004985)
0.2 1.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 4.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 2.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 3.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 16.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 3.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.0 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 2.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 7.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 2.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 7.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 3.1 GO:0005550 pheromone binding(GO:0005550)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 2.4 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.0 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 7.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 8.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 1.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.4 REACTOME OPSINS Genes involved in Opsins
0.1 3.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 3.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)