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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Alx4

Z-value: 0.63

Motif logo

Transcription factors associated with Alx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040310.13 Alx4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx4mm39_v1_chr2_+_93472657_934727330.262.5e-02Click!

Activity profile of Alx4 motif

Sorted Z-values of Alx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_44221791 4.84 ENSMUST00000002274.10
napsin A aspartic peptidase
chr14_+_119025306 3.85 ENSMUST00000047761.13
ENSMUST00000071546.14
claudin 10
chr6_-_68609426 2.75 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr11_-_106205320 2.57 ENSMUST00000167143.2
CD79B antigen
chr2_+_91376650 2.54 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr5_+_13448833 2.40 ENSMUST00000137798.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_20871081 2.36 ENSMUST00000177754.9
DNA methyltransferase (cytosine-5) 1
chr19_-_7688628 2.27 ENSMUST00000025666.8
solute carrier family 22 (organic anion transporter), member 19
chr15_+_89218601 2.18 ENSMUST00000023282.9
myo-inositol oxygenase
chr10_+_103203552 2.16 ENSMUST00000179636.3
ENSMUST00000217905.2
ENSMUST00000074204.12
solute carrier family 6 (neurotransmitter transporter), member 15
chr4_+_19818718 2.03 ENSMUST00000035890.8
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr4_+_145311759 1.96 ENSMUST00000119718.8
zinc finger protein 268
chr7_-_24705320 1.89 ENSMUST00000102858.10
ENSMUST00000196684.2
ENSMUST00000080882.11
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr7_-_83304698 1.88 ENSMUST00000145610.8
interleukin 16
chr3_-_86827664 1.81 ENSMUST00000194452.2
ENSMUST00000191752.6
doublecortin-like kinase 2
chr16_+_45044678 1.79 ENSMUST00000102802.10
ENSMUST00000063654.6
B and T lymphocyte associated
chr19_-_46033353 1.79 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr9_-_14292453 1.77 ENSMUST00000167549.2
endonuclease domain containing 1
chr6_-_87510200 1.76 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chrX_-_133012600 1.75 ENSMUST00000033610.13
NADPH oxidase 1
chr13_-_100922910 1.65 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr3_+_145827410 1.63 ENSMUST00000039450.5
mucolipin 3
chr10_-_62215631 1.63 ENSMUST00000143236.8
ENSMUST00000133429.8
ENSMUST00000132926.8
ENSMUST00000116238.9
hexokinase 1
chr8_-_4829519 1.61 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chrX_-_105264751 1.54 ENSMUST00000113495.9
TATA-box binding protein associated factor 9B
chr11_-_87249837 1.54 ENSMUST00000055438.5
protein phosphatase 1E (PP2C domain containing)
chr14_+_51366512 1.53 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr11_+_46345784 1.53 ENSMUST00000109229.2
hepatitis A virus cellular receptor 2
chr12_-_114012399 1.52 ENSMUST00000103468.3
immunoglobulin heavy variable V11-2
chr13_+_51562675 1.52 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr12_-_114710326 1.47 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr4_-_147894245 1.46 ENSMUST00000105734.10
ENSMUST00000176201.2
zinc finger protein 984
predicted gene 20707
chr15_-_77840856 1.46 ENSMUST00000117725.2
ENSMUST00000016696.13
FAD-dependent oxidoreductase domain containing 2
chrX_+_36390430 1.44 ENSMUST00000016553.5
NFKB activating protein
chr3_-_59060907 1.43 ENSMUST00000196081.5
purinergic receptor P2Y, G-protein coupled, 14
chr8_+_23901506 1.42 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr1_-_171854818 1.41 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr9_+_123902143 1.41 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr11_+_58839716 1.39 ENSMUST00000078267.5
H2B.U histone 2
chr3_-_66204228 1.38 ENSMUST00000029419.8
ventricular zone expressed PH domain-containing 1
chr11_+_46345747 1.37 ENSMUST00000020668.15
hepatitis A virus cellular receptor 2
chr16_-_16687119 1.37 ENSMUST00000075017.5
pre-B lymphocyte gene 1
chr6_+_41498716 1.37 ENSMUST00000070380.5
protease, serine 2
chr11_-_99134885 1.36 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr9_+_92339422 1.35 ENSMUST00000034941.9
phospholipid scramblase 4
chr13_+_76727787 1.35 ENSMUST00000126960.8
ENSMUST00000109583.9
multiple C2 domains, transmembrane 1
chr14_-_104760051 1.33 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr6_-_136852792 1.32 ENSMUST00000032342.3
matrix Gla protein
chr6_+_125192514 1.29 ENSMUST00000032487.14
ENSMUST00000100942.9
ENSMUST00000063588.11
vesicle-associated membrane protein 1
chr3_-_86827640 1.27 ENSMUST00000195561.6
doublecortin-like kinase 2
chr16_+_48692976 1.27 ENSMUST00000065666.6
resistin like gamma
chr6_+_123239076 1.26 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr2_+_124910037 1.26 ENSMUST00000070353.4
solute carrier family 24, member 5
chr6_-_122317484 1.23 ENSMUST00000112600.9
polyhomeotic 1
chr3_+_14545751 1.22 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr2_-_13496624 1.22 ENSMUST00000091436.7
cubilin (intrinsic factor-cobalamin receptor)
chr6_-_115014777 1.21 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr17_-_33252341 1.20 ENSMUST00000087654.5
zinc finger protein 763
chr3_+_55369149 1.20 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr5_-_104261285 1.18 ENSMUST00000199947.2
SPARC-like 1
chr6_-_3399451 1.17 ENSMUST00000120087.6
sterile alpha motif domain containing 9-like
chr12_-_79054050 1.17 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr4_+_103000248 1.16 ENSMUST00000106855.2
MEIR1 treanscription regulator
chr4_+_145311722 1.16 ENSMUST00000105739.8
zinc finger protein 268
chr1_-_152262425 1.16 ENSMUST00000015124.15
tRNA splicing endonuclease subunit 15
chrX_+_16485937 1.15 ENSMUST00000026013.6
monoamine oxidase A
chr6_-_129449739 1.14 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr6_-_69282389 1.14 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr1_+_40478787 1.13 ENSMUST00000097772.10
interleukin 1 receptor-like 1
chr1_-_127605660 1.13 ENSMUST00000160616.8
transmembrane protein 163
chr6_+_41928559 1.12 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr5_+_136023649 1.10 ENSMUST00000111142.9
ENSMUST00000111145.10
ENSMUST00000111144.8
ENSMUST00000199239.5
ENSMUST00000005072.10
ENSMUST00000130345.2
deltex 2, E3 ubiquitin ligase
chr12_+_38833454 1.10 ENSMUST00000161980.8
ENSMUST00000160701.8
ets variant 1
chr15_-_9529898 1.09 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr5_+_13448647 1.09 ENSMUST00000125629.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_131001916 1.08 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr10_+_79832313 1.08 ENSMUST00000132517.8
ATP-binding cassette, sub-family A (ABC1), member 7
chr17_+_66418525 1.08 ENSMUST00000072383.14
WASH complex subunit 1
chr5_-_138169253 1.06 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr11_-_107228382 1.05 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_109247938 1.03 ENSMUST00000046864.14
vav 3 oncogene
chr1_-_83016152 1.02 ENSMUST00000164473.2
ENSMUST00000045560.15
solute carrier family 19, member 3
chr11_-_11920540 1.02 ENSMUST00000109653.8
growth factor receptor bound protein 10
chr5_+_14075281 1.02 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_+_65368207 1.02 ENSMUST00000034955.8
ENSMUST00000213957.2
SPG21, maspardin
chr7_+_89814713 1.02 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr15_+_9436114 1.02 ENSMUST00000042360.5
ENSMUST00000226688.2
calcyphosine-like
chr12_-_75678092 1.02 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr4_+_147216495 1.01 ENSMUST00000084149.10
zinc finger protein 991
chr19_-_32173824 1.01 ENSMUST00000151822.2
sphingomyelin synthase 1
chr4_+_74160705 0.99 ENSMUST00000077851.10
lysine (K)-specific demethylase 4C
chr6_+_70640233 0.99 ENSMUST00000103400.3
immunoglobulin kappa chain variable 3-5
chr5_-_140986312 0.98 ENSMUST00000085786.7
caspase recruitment domain family, member 11
chr2_+_87696836 0.97 ENSMUST00000213308.3
olfactory receptor 1152
chr2_-_73284262 0.97 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr1_+_190660689 0.96 ENSMUST00000066632.14
ENSMUST00000110899.7
angel homolog 2
chr9_+_73009680 0.96 ENSMUST00000034737.13
ENSMUST00000173734.9
ENSMUST00000167514.2
ENSMUST00000174203.3
KH domain containing 3, subcortical maternal complex member
predicted gene 20509
chr5_-_114911548 0.95 ENSMUST00000178440.8
ENSMUST00000043283.14
ENSMUST00000112185.9
ENSMUST00000155908.8
GIT ArfGAP 2
chr7_+_140521450 0.93 ENSMUST00000164580.3
ENSMUST00000079403.11
protein glucosylgalactosylhydroxylysine glucosidase
chr5_-_84565218 0.92 ENSMUST00000113401.4
Eph receptor A5
chr9_-_56151334 0.92 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr4_+_135899678 0.91 ENSMUST00000061721.6
E2F transcription factor 2
chr6_+_68279392 0.91 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr9_+_38738911 0.89 ENSMUST00000051238.7
ENSMUST00000219798.2
olfactory receptor 923
chr9_+_98873831 0.89 ENSMUST00000185472.2
Fas apoptotic inhibitory molecule
chr14_+_62529924 0.89 ENSMUST00000166879.8
ribonuclease H2, subunit B
chr12_+_117807224 0.88 ENSMUST00000021592.16
cell division cycle associated 7 like
chr14_-_59602882 0.88 ENSMUST00000160425.8
ENSMUST00000095157.11
PHD finger protein 11D
chr5_-_23821523 0.87 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr4_-_70328659 0.87 ENSMUST00000144099.8
CDK5 regulatory subunit associated protein 2
chr6_+_41511248 0.85 ENSMUST00000192366.2
ENSMUST00000103286.2
T cell receptor beta joining 1-3
chr11_-_76386190 0.85 ENSMUST00000108408.9
active BCR-related gene
chr14_+_73376192 0.85 ENSMUST00000171070.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_-_114911432 0.85 ENSMUST00000112183.8
GIT ArfGAP 2
chr6_-_69704122 0.85 ENSMUST00000103364.3
immunoglobulin kappa variable 5-48
chr19_+_12647803 0.85 ENSMUST00000207341.3
ENSMUST00000208494.3
ENSMUST00000208657.3
olfactory receptor 1442
chr7_+_19927635 0.84 ENSMUST00000168984.2
vomeronasal 1 receptor, 95
chr6_+_92793440 0.84 ENSMUST00000057977.4
RIKEN cDNA A730049H05 gene
chr10_+_29074950 0.83 ENSMUST00000217011.2
predicted gene, 49353
chr15_-_93493758 0.82 ENSMUST00000048982.11
prickle planar cell polarity protein 1
chr1_-_88205233 0.81 ENSMUST00000065420.12
ENSMUST00000054674.15
Holliday junction recognition protein
chr5_-_114911509 0.81 ENSMUST00000086564.11
GIT ArfGAP 2
chr5_-_151574620 0.81 ENSMUST00000038131.10
replication factor C (activator 1) 3
chr5_+_107645626 0.81 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr3_+_90200470 0.81 ENSMUST00000199754.5
GATA zinc finger domain containing 2B
chr6_+_70648743 0.80 ENSMUST00000103401.3
immunoglobulin kappa variable 3-4
chr2_-_144112700 0.80 ENSMUST00000110030.10
sorting nexin 5
chr9_-_59260713 0.79 ENSMUST00000026265.8
Bardet-Biedl syndrome 4 (human)
chr1_+_160898283 0.79 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr11_+_35011953 0.78 ENSMUST00000069837.4
slit guidance ligand 3
chr3_+_87989278 0.78 ENSMUST00000071812.11
IQ motif containing GTPase activating protein 3
chr4_+_102446883 0.78 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr11_-_58059293 0.78 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr17_+_66418598 0.78 ENSMUST00000116556.4
ENSMUST00000233354.2
WASH complex subunit 1
chr2_-_126342551 0.77 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr15_+_80017315 0.77 ENSMUST00000023050.9
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr1_-_152262339 0.77 ENSMUST00000162371.2
tRNA splicing endonuclease subunit 15
chr11_+_106107752 0.76 ENSMUST00000021046.6
DEAD box helicase 42
chr14_+_15369152 0.76 ENSMUST00000167923.8
predicted gene 3696
chr16_-_45544960 0.75 ENSMUST00000096057.5
transgelin 3
chr9_+_118892497 0.74 ENSMUST00000141185.8
ENSMUST00000126251.8
ENSMUST00000136561.2
villin-like
chr3_-_105839980 0.74 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr19_-_8796288 0.74 ENSMUST00000153281.2
tetratricopeptide repeat domain 9C
chr3_-_113325938 0.74 ENSMUST00000132353.2
amylase 2a1
chr5_-_138169509 0.74 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr12_-_69939931 0.73 ENSMUST00000049239.8
ENSMUST00000110570.8
mitogen-activated protein kinase kinase kinase kinase 5
chr5_-_65855511 0.73 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr6_-_68887957 0.72 ENSMUST00000200454.2
immunoglobulin kappa variable 4-86
chr2_-_111843053 0.72 ENSMUST00000213559.3
olfactory receptor 1310
chrX_-_121307036 0.72 ENSMUST00000079490.6
nucleosome assembly protein 1-like 3
chr6_+_41512010 0.72 ENSMUST00000103288.2
T cell receptor beta joining 1-5
chr15_-_36794741 0.72 ENSMUST00000110361.8
ENSMUST00000022894.14
ENSMUST00000110359.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr10_+_80003612 0.72 ENSMUST00000105365.9
cold inducible RNA binding protein
chr19_+_5524701 0.72 ENSMUST00000165485.8
ENSMUST00000166253.8
ENSMUST00000167371.8
ENSMUST00000167855.8
ENSMUST00000070118.14
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr11_-_29197222 0.72 ENSMUST00000020754.10
cilia and flagella associated protein 36
chr6_+_129022843 0.71 ENSMUST00000032257.10
ENSMUST00000204320.2
killer cell lectin-like receptor subfamily B member 1F
chr14_+_53599724 0.71 ENSMUST00000196105.2
T cell receptor alpha variable 13N-4
chr5_+_121601212 0.70 ENSMUST00000094357.11
ENSMUST00000031405.12
transmembrane protein 116
chr4_-_136329953 0.70 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr4_+_12906838 0.70 ENSMUST00000143186.8
ENSMUST00000183345.2
triple QxxK/R motif containing
chr3_+_142326363 0.69 ENSMUST00000165774.8
guanylate binding protein 2
chr2_-_29677634 0.69 ENSMUST00000177467.8
ENSMUST00000113807.10
TruB pseudouridine (psi) synthase family member 2
chr4_-_106536063 0.69 ENSMUST00000106772.10
ENSMUST00000135676.2
ENSMUST00000026480.13
tetratricopeptide repeat domain 4
chr17_-_21110913 0.69 ENSMUST00000061278.2
vomeronasal 1 receptor 231
chrX_+_56257374 0.69 ENSMUST00000033466.2
CD40 ligand
chr2_-_88157559 0.68 ENSMUST00000214207.2
olfactory receptor 1175
chr2_-_73490746 0.68 ENSMUST00000102677.11
chimerin 1
chr18_+_37898633 0.67 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr12_-_113790741 0.67 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr6_+_57180275 0.67 ENSMUST00000226892.2
ENSMUST00000227421.2
vomeronasal 1 receptor 13
chr5_-_3691453 0.65 ENSMUST00000140871.2
GATA zinc finger domain containing 1
chr15_-_79658584 0.65 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr15_-_66985760 0.65 ENSMUST00000092640.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr11_+_100900278 0.65 ENSMUST00000103110.10
ENSMUST00000044721.13
ENSMUST00000168757.9
ATPase, H+ transporting, lysosomal V0 subunit A1
chr9_-_123507937 0.65 ENSMUST00000040960.13
solute carrier family 6 (neurotransmitter transporter), member 20A
chr19_-_10807409 0.64 ENSMUST00000080292.12
CD6 antigen
chr7_-_30259025 0.64 ENSMUST00000043975.11
ENSMUST00000156241.2
lin-37 homolog (C. elegans)
chr19_-_10807285 0.64 ENSMUST00000039043.15
CD6 antigen
chr10_+_129493563 0.64 ENSMUST00000217094.2
olfactory receptor 800
chr5_+_3593811 0.63 ENSMUST00000197082.5
ENSMUST00000115527.8
family with sequence similarity 133, member B
chr9_-_123507847 0.63 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr13_+_67961859 0.62 ENSMUST00000181391.8
ENSMUST00000012725.8
zinc finger protein 273
chr6_-_66537080 0.62 ENSMUST00000079584.3
ENSMUST00000227014.2
vomeronasal 1 receptor 32
chr12_-_69939762 0.62 ENSMUST00000110567.8
ENSMUST00000171211.8
mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_35188888 0.62 ENSMUST00000173680.2
predicted gene 20481
chr5_+_27022355 0.62 ENSMUST00000071500.13
dipeptidylpeptidase 6
chr4_+_146695418 0.62 ENSMUST00000130825.8
zinc finger protein 993
chr9_-_22171180 0.61 ENSMUST00000086281.5
zinc finger protein 599
chr2_-_34716199 0.61 ENSMUST00000113075.8
ENSMUST00000113080.9
ENSMUST00000091020.10
F-box and WD-40 domain protein 2
chr19_-_11582207 0.60 ENSMUST00000025582.11
membrane-spanning 4-domains, subfamily A, member 6D
chr11_+_102080489 0.59 ENSMUST00000078975.8
glucose 6 phosphatase, catalytic, 3
chr15_-_79658608 0.59 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr2_+_174169539 0.59 ENSMUST00000133356.8
ENSMUST00000087871.11
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr5_-_108943211 0.58 ENSMUST00000004943.2
transmembrane p24 trafficking protein 11
chr4_-_135714465 0.58 ENSMUST00000105851.9
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr4_-_43710231 0.58 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr8_-_86091946 0.57 ENSMUST00000034133.14
myosin light chain kinase 3
chr7_-_30523191 0.57 ENSMUST00000053156.10
free fatty acid receptor 2
chr7_-_30259253 0.57 ENSMUST00000108164.8
lin-37 homolog (C. elegans)
chr10_-_128462616 0.56 ENSMUST00000026420.7
ribosomal protein S26

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.7 2.9 GO:0002856 negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256) negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.6 1.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 2.4 GO:0090309 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.5 1.4 GO:2000040 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 1.4 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.5 1.4 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.4 2.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 2.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.4 1.6 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.4 1.1 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.3 1.4 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.3 1.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.3 1.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 1.3 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 2.2 GO:0015824 proline transport(GO:0015824)
0.3 4.8 GO:0043129 surfactant homeostasis(GO:0043129)
0.3 2.3 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.3 0.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.9 GO:1904109 positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.2 0.7 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.2 1.0 GO:0015888 thiamine transport(GO:0015888)
0.2 1.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 0.8 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 1.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 0.7 GO:0046098 guanine metabolic process(GO:0046098)
0.2 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 1.0 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 2.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 2.2 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 1.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.3 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 1.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0002879 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.4 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.1 0.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.3 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.1 1.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 1.9 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 1.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.1 1.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 1.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.3 GO:0061738 mitotic cytokinesis checkpoint(GO:0044878) late endosomal microautophagy(GO:0061738)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.6 GO:0001771 immunological synapse formation(GO:0001771)
0.1 0.4 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 2.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.4 GO:0031000 response to caffeine(GO:0031000)
0.1 0.3 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 1.0 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.6 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 1.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.3 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 1.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 8.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 1.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.4 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.4 GO:2001198 regulation of dendritic cell differentiation(GO:2001198) negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.7 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 5.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0006907 pinocytosis(GO:0006907)
0.0 0.9 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 1.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.4 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.3 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:1901750 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 1.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.7 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060187 cell pole(GO:0060187)
0.4 1.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 4.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.4 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 2.1 GO:0071438 invadopodium membrane(GO:0071438)
0.3 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.2 GO:0043202 lysosomal lumen(GO:0043202)
0.2 1.3 GO:0070820 tertiary granule(GO:0070820)
0.2 0.9 GO:0030312 external encapsulating structure(GO:0030312)
0.2 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 1.9 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 1.9 GO:0071203 WASH complex(GO:0071203)
0.1 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0097422 extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.1 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 3.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.6 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.9 GO:0001772 immunological synapse(GO:0001772)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 0.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 1.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 4.1 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 1.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.0 GO:0030286 dynein complex(GO:0030286)
0.0 7.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.4 1.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 1.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 1.1 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 2.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 3.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 1.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 4.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 1.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 1.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 1.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 0.8 GO:0030622 U4atac snRNA binding(GO:0030622)
0.3 1.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 4.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 1.6 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 2.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.6 GO:0034452 dynactin binding(GO:0034452)
0.2 1.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 1.2 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.2 GO:0008199 ferric iron binding(GO:0008199)
0.2 2.3 GO:0019534 toxin transporter activity(GO:0019534)
0.1 4.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.5 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 1.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.1 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0015926 glucosidase activity(GO:0015926)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 5.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 3.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 3.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 6.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.7 GO:0005550 pheromone binding(GO:0005550)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID ATR PATHWAY ATR signaling pathway
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 3.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID IGF1 PATHWAY IGF1 pathway
0.0 2.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.7 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 2.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 3.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling