Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Ar

Z-value: 1.90

Motif logo

Transcription factors associated with Ar

Gene Symbol Gene ID Gene Info
ENSMUSG00000046532.9 Ar

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Armm39_v1_chrX_+_97192356_97192388-0.603.3e-08Click!

Activity profile of Ar motif

Sorted Z-values of Ar motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ar

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr1_+_152626273 13.99 ENSMUST00000068875.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr2_-_32277773 9.99 ENSMUST00000050785.14
lipocalin 2
chr2_+_118998235 9.63 ENSMUST00000057454.4
GTP cyclohydrolase I feedback regulator
chr11_-_69712970 8.32 ENSMUST00000045771.7
sperm maturation 1
chr6_-_69678271 7.95 ENSMUST00000103363.2
immunoglobulin kappa variable 4-50
chr11_+_108286114 7.91 ENSMUST00000000049.6
apolipoprotein H
chr15_-_85705935 7.75 ENSMUST00000064370.6
polycystin (PKD) family receptor for egg jelly
chr9_-_22043083 7.71 ENSMUST00000069330.14
ENSMUST00000217643.2
acid phosphatase 5, tartrate resistant
chr8_+_123912976 7.56 ENSMUST00000019422.6
dipeptidase 1
chr17_+_80434874 7.46 ENSMUST00000039205.11
galactose mutarotase
chr9_+_7692087 7.29 ENSMUST00000018767.8
matrix metallopeptidase 7
chr2_+_24970327 7.14 ENSMUST00000044078.10
ENSMUST00000114380.9
ectonucleoside triphosphate diphosphohydrolase 8
chr15_+_75088445 6.93 ENSMUST00000055719.8
lymphocyte antigen 6 complex, locus G2
chr1_+_13738967 6.91 ENSMUST00000088542.4
X-linked Kx blood group related 9
chr10_-_99595498 6.75 ENSMUST00000056085.6
citrate synthase like
chr8_+_21624626 6.75 ENSMUST00000098898.5
defensin, alpha, 30
chr16_-_18880821 6.70 ENSMUST00000200568.2
immunoglobulin lambda constant 1
chr7_+_30676465 6.62 ENSMUST00000058093.6
family with sequence similarity 187, member B
chr1_+_172525613 6.47 ENSMUST00000038495.5
C-reactive protein, pentraxin-related
chr4_+_134042423 6.42 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr2_-_32278245 6.41 ENSMUST00000192241.2
lipocalin 2
chr9_-_22042930 6.33 ENSMUST00000213815.2
acid phosphatase 5, tartrate resistant
chr9_+_48406706 6.32 ENSMUST00000048824.9
predicted gene 5617
chr14_-_33996185 6.29 ENSMUST00000227006.2
shieldin complex subunit 2
chr7_+_79896121 6.26 ENSMUST00000058266.9
tubulin tyrosine ligase-like family, member 13
chr6_-_72212547 6.25 ENSMUST00000042646.8
atonal bHLH transcription factor 8
chr4_-_141345549 6.17 ENSMUST00000053263.9
transmembrane protein 82
chr4_-_44710408 6.16 ENSMUST00000134968.9
ENSMUST00000173821.8
ENSMUST00000174319.8
ENSMUST00000173733.8
ENSMUST00000172866.8
ENSMUST00000165417.9
ENSMUST00000107825.9
ENSMUST00000102932.10
ENSMUST00000107827.9
ENSMUST00000107826.9
ENSMUST00000014174.14
paired box 5
chr7_-_19415301 6.12 ENSMUST00000150569.9
ENSMUST00000127648.4
ENSMUST00000003071.10
predicted gene 44805
apolipoprotein C-IV
chr1_+_88015524 6.12 ENSMUST00000113139.2
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_-_21946576 6.11 ENSMUST00000110752.4
defensin, alpha, 42
chr5_-_134944366 6.11 ENSMUST00000008987.5
claudin 13
chr2_-_162929732 6.04 ENSMUST00000094653.6
gametocyte specific factor 1-like
chr11_-_58343747 6.01 ENSMUST00000064614.4
LY6/PLAUR domain containing 9
chr4_-_49408040 5.95 ENSMUST00000081541.9
acyl-coenzyme A amino acid N-acyltransferase 2
chr8_-_22193658 5.95 ENSMUST00000071886.7
defensin, alpha, 39
chr11_-_75330415 5.93 ENSMUST00000128330.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr11_+_96822213 5.91 ENSMUST00000107633.2
proline rich 15-like
chr8_+_22224506 5.88 ENSMUST00000080533.6
defensin, alpha, 24
chr3_+_97536120 5.86 ENSMUST00000107050.8
ENSMUST00000029729.15
ENSMUST00000107049.2
flavin containing monooxygenase 5
chr1_+_88128323 5.75 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr17_-_84154173 5.70 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr14_+_15137378 5.61 ENSMUST00000100886.4
predicted gene 5797
chr7_+_43701714 5.51 ENSMUST00000079859.7
kallikrein 1-related peptidase b27
chr14_+_16343966 5.50 ENSMUST00000112742.4
ENSMUST00000167913.8
predicted gene 3476
chr1_-_53226756 5.44 ENSMUST00000190748.2
ENSMUST00000072235.10
RIKEN cDNA 1700019A02 gene
chr8_-_21586066 5.44 ENSMUST00000077452.4
defensin, alpha, 38
chr14_-_18152432 5.43 ENSMUST00000171810.8
ENSMUST00000112779.10
predicted gene 3149
chr14_+_15695362 5.37 ENSMUST00000170673.2
ENSMUST00000168790.8
predicted gene 8362
chr11_-_75330302 5.37 ENSMUST00000043696.9
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr7_+_118199375 5.32 ENSMUST00000121744.9
transmembrane channel-like gene family 5
chr8_+_21545063 5.28 ENSMUST00000098899.4
defensin, alpha, 23
chr7_-_46392403 5.28 ENSMUST00000128088.4
serum amyloid A 1
chr11_-_78313043 5.24 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr16_-_97306125 5.24 ENSMUST00000049721.9
ENSMUST00000231999.2
family with sequence similarity 3, member B
chr1_+_177557380 5.23 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr8_+_22145796 5.22 ENSMUST00000079528.6
defensin, alpha, 17
chr12_-_113790741 5.20 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr6_+_124489364 5.10 ENSMUST00000068593.9
complement component 1, r subcomponent A
chr6_+_138119851 5.07 ENSMUST00000125810.2
microsomal glutathione S-transferase 1
chr7_+_119125546 5.06 ENSMUST00000207387.2
ENSMUST00000207813.2
acyl-CoA synthetase medium-chain family member 5
chr1_-_167294349 5.04 ENSMUST00000036643.6
leucine rich repeat containing 52
chr12_+_31440842 5.01 ENSMUST00000167432.8
solute carrier family 26, member 3
chr19_+_43770619 4.99 ENSMUST00000026208.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chrX_-_126644166 4.97 ENSMUST00000052500.6
claudin 34C4
chr10_-_117118226 4.95 ENSMUST00000092163.9
lysozyme 2
chr8_+_120301974 4.95 ENSMUST00000093100.3
dynein, axonemal assembly factor 1
chr6_-_68681962 4.90 ENSMUST00000103330.2
immunoglobulin kappa variable 10-94
chr5_+_25721059 4.89 ENSMUST00000045016.9
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr5_-_24760401 4.89 ENSMUST00000088302.10
IQ motif containing with AAA domain 1 like
chr1_+_165958036 4.88 ENSMUST00000166860.2
glycoprotein A33 (transmembrane)
chr17_-_84154196 4.83 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr12_-_103597663 4.77 ENSMUST00000121625.2
ENSMUST00000044231.12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr17_-_12894716 4.75 ENSMUST00000024596.10
solute carrier family 22 (organic cation transporter), member 1
chr16_-_18884431 4.68 ENSMUST00000200235.2
immunoglobulin lambda constant 3
chr7_+_28682253 4.67 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr2_+_156681927 4.65 ENSMUST00000081335.13
TGFB-induced factor homeobox 2
chr15_+_7159038 4.63 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr2_-_28453374 4.58 ENSMUST00000028161.6
carboxyl ester lipase
chr8_+_21777425 4.56 ENSMUST00000098893.4
defensin, alpha, 3
chr6_+_29279582 4.55 ENSMUST00000167131.8
family with sequence similarity 71, member F2
chr3_+_10431961 4.51 ENSMUST00000029049.7
charged multivesicular body protein 4C
chr3_-_98721750 4.43 ENSMUST00000029463.13
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr15_-_82291372 4.43 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr5_+_90608751 4.41 ENSMUST00000031314.10
albumin
chr4_+_116565706 4.39 ENSMUST00000030452.13
ENSMUST00000106462.9
coiled-coil domain containing 163
chr11_+_62842019 4.37 ENSMUST00000035854.4
CMT1A duplicated region transcript 4
chr7_+_119125443 4.34 ENSMUST00000207440.2
acyl-CoA synthetase medium-chain family member 5
chr16_-_97564910 4.32 ENSMUST00000019386.10
receptor-interacting serine-threonine kinase 4
chr3_+_146276147 4.30 ENSMUST00000199489.5
urate oxidase
chr8_-_22084524 4.29 ENSMUST00000110749.4
defensin, alpha, 43
chr1_-_136876902 4.27 ENSMUST00000195428.2
nuclear receptor subfamily 5, group A, member 2
chrX_-_101751241 4.26 ENSMUST00000113610.3
predicted gene 9112
chr5_-_145521533 4.23 ENSMUST00000075837.8
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr8_+_84728123 4.20 ENSMUST00000060357.15
ENSMUST00000239176.2
RIKEN cDNA 1700067K01 gene
chr15_-_102112159 4.20 ENSMUST00000229252.2
ENSMUST00000229770.2
cysteine sulfinic acid decarboxylase
chr8_+_118428643 4.15 ENSMUST00000034304.9
hydroxysteroid (17-beta) dehydrogenase 2
chr7_+_119125426 4.14 ENSMUST00000066465.3
acyl-CoA synthetase medium-chain family member 5
chr10_-_39901249 4.12 ENSMUST00000163705.3
major facilitator superfamily domain containing 4B1
chr12_-_28632514 4.06 ENSMUST00000110917.2
ENSMUST00000020965.14
allantoicase
chr5_-_144969564 4.05 ENSMUST00000071421.6
predicted gene 4871
chr17_+_48400153 4.03 ENSMUST00000233043.2
RIKEN cDNA 1700067P10 gene
chr14_+_16164930 3.99 ENSMUST00000112737.10
ENSMUST00000170923.9
predicted gene, 21103
chr16_-_95993420 3.98 ENSMUST00000113804.8
ENSMUST00000054855.14
Leber congenital amaurosis 5-like
chr5_+_144979796 3.96 ENSMUST00000031624.5
RIKEN cDNA 1700018F24 gene
chrX_+_101952505 3.95 ENSMUST00000113602.2
RIKEN cDNA 1700011M02 gene
chr2_-_129139125 3.95 ENSMUST00000052708.7
cytoskeleton associated protein 2-like
chr19_+_5928649 3.94 ENSMUST00000136833.8
ENSMUST00000141362.2
solute carrier family 25, member 45
chr5_+_146492946 3.93 ENSMUST00000179214.8
ENSMUST00000110595.3
predicted gene 3415
chr4_+_116565819 3.93 ENSMUST00000106463.8
coiled-coil domain containing 163
chr1_+_165957784 3.92 ENSMUST00000060833.14
glycoprotein A33 (transmembrane)
chr5_+_146474457 3.92 ENSMUST00000199142.5
ENSMUST00000110597.4
ENSMUST00000110599.9
predicted gene 3409
chr12_+_113112311 3.90 ENSMUST00000199089.5
cysteine-rich protein 1 (intestinal)
chr11_-_99045894 3.86 ENSMUST00000103134.4
chemokine (C-C motif) receptor 7
chr2_+_148623929 3.84 ENSMUST00000028933.3
cystatin domain containing 1
chr17_+_25381414 3.83 ENSMUST00000073277.12
ENSMUST00000182621.8
coiled-coil domain containing 154
chr15_-_96917804 3.81 ENSMUST00000231039.2
solute carrier family 38, member 4
chr14_-_18538017 3.80 ENSMUST00000168306.8
predicted gene 3029
chr17_-_35394971 3.77 ENSMUST00000173324.8
allograft inflammatory factor 1
chr14_-_17485779 3.76 ENSMUST00000171964.8
ENSMUST00000171636.8
predicted gene 8297
chr10_+_128104525 3.75 ENSMUST00000050901.5
apolipoprotein F
chr5_-_24760427 3.74 ENSMUST00000198887.2
IQ motif containing with AAA domain 1 like
chrX_-_101730578 3.74 ENSMUST00000122154.3
predicted pseudogene 3880
chr2_+_152804405 3.71 ENSMUST00000099197.9
ENSMUST00000103155.10
tubulin tyrosine ligase-like family, member 9
chr13_-_99121070 3.70 ENSMUST00000054425.7
H2B.L histone variant 1
chr5_+_42225303 3.69 ENSMUST00000087332.5
predicted gene 16223
chr14_-_17837363 3.67 ENSMUST00000170546.8
ENSMUST00000163738.8
predicted gene 8159
chr11_+_105866030 3.65 ENSMUST00000001964.8
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr7_+_75879603 3.64 ENSMUST00000156166.8
ATP/GTP binding protein-like 1
chr14_-_19652649 3.62 ENSMUST00000096121.12
predicted gene 5458
chr1_+_175459559 3.62 ENSMUST00000040250.15
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_-_134985958 3.60 ENSMUST00000138878.2
ENSMUST00000080929.13
nuclear RNA export factor 3
chr17_-_7620095 3.60 ENSMUST00000115747.3
tubulin tyrosine ligase-like family, member 2
chr14_-_17338198 3.59 ENSMUST00000165713.8
ENSMUST00000112767.9
predicted gene 8279
chr9_+_78137927 3.59 ENSMUST00000098537.4
glutathione S-transferase, alpha 1 (Ya)
chr14_-_18835261 3.58 ENSMUST00000112802.9
predicted gene 3012
chr14_-_19074680 3.58 ENSMUST00000112728.9
predicted gene 10413
chr15_-_41733099 3.55 ENSMUST00000054742.7
actin-binding Rho activating protein
chr11_-_4390745 3.53 ENSMUST00000109948.8
HORMA domain containing 2
chr15_+_75468473 3.52 ENSMUST00000189944.7
ENSMUST00000023243.11
GPI-anchored HDL-binding protein 1
chr8_+_21681630 3.49 ENSMUST00000098896.5
defensin, alpha, 31
chr2_-_24825066 3.45 ENSMUST00000132074.2
arrestin domain containing 1
chr14_-_21792938 3.45 ENSMUST00000120956.8
dual specificity phosphatase 13
chr5_-_145656934 3.45 ENSMUST00000094111.6
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr7_+_43090206 3.43 ENSMUST00000040227.3
claudin domain containing 2
chr9_+_110248815 3.42 ENSMUST00000035061.9
neutrophilic granule protein
chr1_+_135060431 3.40 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr2_-_164621641 3.39 ENSMUST00000103095.5
troponin C2, fast
chr8_-_107792264 3.37 ENSMUST00000034393.7
transmembrane p24 trafficking protein 6
chr2_-_10135449 3.36 ENSMUST00000042290.14
inter-alpha trypsin inhibitor, heavy chain 2
chr9_-_72892617 3.35 ENSMUST00000124565.3
cell cycle progression 1, opposite strand
chr11_-_86999481 3.35 ENSMUST00000051395.9
proline rich 11
chr14_-_18304685 3.33 ENSMUST00000171866.8
ENSMUST00000167839.8
predicted gene 3127
chr11_-_4391082 3.32 ENSMUST00000109949.8
ENSMUST00000130174.2
HORMA domain containing 2
chr4_+_116565784 3.32 ENSMUST00000138305.8
ENSMUST00000125671.8
ENSMUST00000130828.8
coiled-coil domain containing 163
chr10_-_93375832 3.31 ENSMUST00000016034.3
amidohydrolase domain containing 1
chr18_-_43610829 3.30 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr5_+_146428173 3.29 ENSMUST00000110611.8
ENSMUST00000198912.2
predicted gene 6370
chr17_+_18108086 3.27 ENSMUST00000149944.2
formyl peptide receptor 2
chr8_-_116434517 3.27 ENSMUST00000109104.2
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr4_+_116565898 3.27 ENSMUST00000135499.8
coiled-coil domain containing 163
chr17_-_13159204 3.25 ENSMUST00000043923.12
acetyl-Coenzyme A acetyltransferase 3
chr7_-_114162125 3.22 ENSMUST00000211506.2
ENSMUST00000119712.8
ENSMUST00000032908.15
cytochrome P450, family 2, subfamily r, polypeptide 1
chr5_+_8010445 3.22 ENSMUST00000115421.3
STEAP family member 4
chr2_-_153286361 3.21 ENSMUST00000109784.2
nucleolar protein 4-like
chr11_+_58269862 3.20 ENSMUST00000013787.11
ENSMUST00000108826.3
LY6/PLAUR domain containing 8
chr1_+_165957909 3.20 ENSMUST00000166159.2
glycoprotein A33 (transmembrane)
chr4_+_150171822 3.20 ENSMUST00000094451.4
G protein-coupled receptor 157
chr5_+_146450933 3.20 ENSMUST00000200228.5
ENSMUST00000036715.16
ENSMUST00000077133.7
predicted gene 3402
chr14_+_15424803 3.19 ENSMUST00000169215.8
predicted gene 3685
chr7_-_81216687 3.18 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr9_-_63056197 3.18 ENSMUST00000116613.9
SKI family transcriptional corepressor 1
chr2_+_153684901 3.17 ENSMUST00000175856.3
EF-hand calcium binding domain 8
chr15_-_79626719 3.14 ENSMUST00000089311.11
ENSMUST00000046259.14
Sad1 and UNC84 domain containing 2
chr5_+_146418775 3.14 ENSMUST00000179032.3
predicted gene 6408
chr14_+_15847355 3.13 ENSMUST00000167882.8
predicted gene 3460
chr14_+_14874181 3.13 ENSMUST00000096148.11
predicted gene 10338
chr6_+_29433247 3.12 ENSMUST00000101617.9
ENSMUST00000065090.8
filamin C, gamma
chr12_+_101370932 3.12 ENSMUST00000055156.5
cation channel sperm associated auxiliary subunit beta
chr7_+_43751749 3.12 ENSMUST00000085455.6
kallikrein 1-related peptidase b21
chrX_-_154121454 3.12 ENSMUST00000026328.11
peroxiredoxin 4
chr12_+_116239006 3.11 ENSMUST00000090195.5
predicted gene 11027
chr7_-_126275529 3.11 ENSMUST00000106372.11
ENSMUST00000155419.3
ENSMUST00000106373.9
sulfotransferase family 1A, phenol-preferring, member 1
chr17_+_24971952 3.10 ENSMUST00000044922.8
ENSMUST00000234202.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr2_+_58644922 3.09 ENSMUST00000059102.13
uridine phosphorylase 2
chr14_+_66043515 3.06 ENSMUST00000139644.2
PDZ binding kinase
chr14_-_19281460 3.06 ENSMUST00000171150.8
ENSMUST00000100920.10
predicted gene 5795
chr2_+_172314433 3.05 ENSMUST00000029007.3
family with sequence similarity 209
chr5_-_146107531 3.03 ENSMUST00000174320.2
predicted gene 6309
chr5_+_146439209 3.03 ENSMUST00000110598.3
RIKEN cDNA 4930449I24 gene
chr1_+_175459735 3.02 ENSMUST00000097458.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr19_-_5610628 3.01 ENSMUST00000025861.3
ovo like zinc finger 1
chr13_+_84370405 3.01 ENSMUST00000057495.10
ENSMUST00000225069.2
transmembrane protein 161B
chr14_+_15104639 3.01 ENSMUST00000163826.2
predicted gene 8374
chr19_+_12673147 3.00 ENSMUST00000025598.10
ENSMUST00000138545.8
ENSMUST00000154822.2
kidney expressed gene 1
chr2_+_164557219 2.99 ENSMUST00000103097.10
ENSMUST00000180193.2
serine protease inhibitor, Kunitz type 5
chr14_-_17987965 2.99 ENSMUST00000167902.2
ENSMUST00000169364.8
predicted gene 3182
chr5_-_31854942 2.97 ENSMUST00000031018.10
ribokinase
chr1_+_139429430 2.96 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr15_+_89452529 2.96 ENSMUST00000023295.3
ENSMUST00000230538.2
ENSMUST00000230978.2
acrosin prepropeptide

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.1 12.6 GO:0016999 antibiotic metabolic process(GO:0016999)
2.6 20.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.4 7.3 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
2.1 6.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.0 6.0 GO:0090320 regulation of chylomicron remnant clearance(GO:0090320)
1.9 17.2 GO:0046874 quinolinate metabolic process(GO:0046874)
1.9 7.5 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
1.8 5.3 GO:0046967 cytosol to ER transport(GO:0046967)
1.7 19.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.6 7.9 GO:0042412 taurine biosynthetic process(GO:0042412)
1.5 18.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.5 4.5 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
1.5 4.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
1.3 3.9 GO:0097021 regulation of tolerance induction to self antigen(GO:0002649) lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
1.3 5.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.3 3.8 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
1.2 6.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.1 5.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
1.0 5.2 GO:0006548 histidine catabolic process(GO:0006548)
1.0 3.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.0 6.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.9 2.8 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.9 2.8 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.9 2.6 GO:0046100 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.9 3.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.8 5.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.8 1.6 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.8 4.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.8 6.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.7 3.0 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 3.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.7 4.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.7 4.3 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.7 5.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.7 4.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.7 4.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 3.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.6 3.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.6 1.9 GO:0072347 response to anesthetic(GO:0072347)
0.5 7.1 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.5 1.6 GO:0009629 response to gravity(GO:0009629)
0.5 2.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.5 2.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.5 6.9 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.5 4.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.5 4.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.5 1.8 GO:2000521 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.4 9.8 GO:0021670 lateral ventricle development(GO:0021670)
0.4 1.7 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.4 2.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 1.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.4 3.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 4.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.9 GO:0002432 granuloma formation(GO:0002432)
0.4 3.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.4 4.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.4 2.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 2.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.3 2.4 GO:0001757 somite specification(GO:0001757)
0.3 5.0 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.3 3.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 3.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 2.2 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.3 0.9 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.3 2.1 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.3 4.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.3 1.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 5.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 3.9 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 1.9 GO:0031179 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 6.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.9 GO:0061739 aggrephagy(GO:0035973) protein lipidation involved in autophagosome assembly(GO:0061739)
0.2 1.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 4.3 GO:0046415 urate metabolic process(GO:0046415)
0.2 1.3 GO:1990839 response to endothelin(GO:1990839)
0.2 2.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 1.6 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 1.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 30.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 3.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2 5.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 1.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 2.3 GO:0045759 negative regulation of action potential(GO:0045759)
0.2 3.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 1.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 1.7 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 3.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.2 4.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 4.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 0.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 2.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 3.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 16.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.1 7.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.6 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 4.0 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 1.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 3.6 GO:0035634 response to stilbenoid(GO:0035634)
0.1 5.1 GO:0006953 acute-phase response(GO:0006953)
0.1 4.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 3.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 26.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.1 3.7 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 2.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.1 1.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 1.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.3 GO:0008272 sulfate transport(GO:0008272)
0.1 3.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.9 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 2.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 4.6 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 3.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 1.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 1.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.0 3.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258) regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 2.2 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.9 GO:0003341 cilium movement(GO:0003341)
0.0 2.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 3.1 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.3 GO:0007625 grooming behavior(GO:0007625)
0.0 7.7 GO:0007596 blood coagulation(GO:0007596)
0.0 2.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.7 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 1.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.9 GO:0001832 blastocyst growth(GO:0001832)
0.0 1.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.7 GO:0034508 centromere complex assembly(GO:0034508)
0.0 3.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 2.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.5 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 2.9 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.6 GO:0002088 lens development in camera-type eye(GO:0002088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.3 11.3 GO:0005577 fibrinogen complex(GO:0005577)
1.2 3.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.9 4.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.7 3.0 GO:0043159 acrosomal matrix(GO:0043159)
0.7 29.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.7 5.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 6.7 GO:0019815 B cell receptor complex(GO:0019815)
0.7 5.3 GO:0042825 TAP complex(GO:0042825)
0.5 2.7 GO:0044194 cytolytic granule(GO:0044194)
0.5 2.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.5 5.4 GO:0045098 type III intermediate filament(GO:0045098)
0.5 8.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 1.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 1.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.4 2.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 2.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 2.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 0.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 5.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 8.7 GO:0097225 sperm midpiece(GO:0097225)
0.3 4.5 GO:0090543 Flemming body(GO:0090543)
0.2 9.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 3.1 GO:0036128 CatSper complex(GO:0036128)
0.2 2.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 2.0 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.6 GO:0070992 translation initiation complex(GO:0070992)
0.2 6.4 GO:0042588 zymogen granule(GO:0042588)
0.2 0.7 GO:0036284 tubulobulbar complex(GO:0036284)
0.2 3.4 GO:0005861 troponin complex(GO:0005861)
0.2 3.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 20.5 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.1 0.8 GO:0070449 elongin complex(GO:0070449)
0.1 2.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 2.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 3.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 13.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 7.8 GO:0031970 organelle envelope lumen(GO:0031970)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 3.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.2 GO:0060170 ciliary membrane(GO:0060170)
0.1 14.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.8 GO:0097386 glial cell projection(GO:0097386)
0.0 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 12.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 7.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 7.2 GO:0001650 fibrillar center(GO:0001650)
0.0 66.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.8 5.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.7 1.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.7 6.9 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
1.7 13.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.6 11.2 GO:0070573 metallodipeptidase activity(GO:0070573)
1.6 4.8 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
1.5 4.6 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
1.3 7.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.2 6.0 GO:0035478 chylomicron binding(GO:0035478)
1.1 7.9 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.1 5.5 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.1 12.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.0 7.7 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.9 4.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.9 5.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 6.5 GO:0001849 complement component C1q binding(GO:0001849)
0.8 14.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.8 3.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.7 2.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 4.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.6 3.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.6 3.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.6 1.8 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.6 2.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.6 14.9 GO:0019825 oxygen binding(GO:0019825)
0.5 1.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.5 1.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.5 4.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5 3.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5 1.5 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.5 1.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.5 3.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.4 18.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 7.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.4 5.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 4.3 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.4 6.4 GO:0031432 titin binding(GO:0031432)
0.4 2.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.4 3.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 4.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 3.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 3.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 6.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 7.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 0.9 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.3 16.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.3 3.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 8.6 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 4.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 0.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 1.4 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3 5.0 GO:0003796 lysozyme activity(GO:0003796)
0.3 1.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 9.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 1.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.7 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.2 1.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 1.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 27.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 3.9 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 2.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 1.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 4.4 GO:0070330 aromatase activity(GO:0070330)
0.1 3.5 GO:0005537 mannose binding(GO:0005537)
0.1 5.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 5.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 19.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 4.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 2.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 4.2 GO:0008009 chemokine activity(GO:0008009)
0.1 2.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 19.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.1 GO:0038064 collagen receptor activity(GO:0038064)
0.1 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.2 GO:0005521 lamin binding(GO:0005521)
0.1 2.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 2.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 10.1 GO:0005506 iron ion binding(GO:0005506)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 6.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 7.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 9.4 GO:0015293 symporter activity(GO:0015293)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.4 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.8 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 3.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0030553 cGMP binding(GO:0030553)
0.0 1.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 5.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 3.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 5.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 17.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 7.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 6.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 7.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 15.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 5.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 4.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 17.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.7 8.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.6 4.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 9.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.4 5.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 4.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 4.6 REACTOME DEFENSINS Genes involved in Defensins
0.3 5.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 7.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 4.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 5.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 5.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 7.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 10.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 7.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 8.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 7.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 4.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 11.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 4.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 4.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.6 REACTOME KINESINS Genes involved in Kinesins
0.1 3.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 8.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 10.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 7.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.6 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 1.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 3.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 3.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand