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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Arid5a

Z-value: 0.51

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Transcription factors associated with Arid5a

Gene Symbol Gene ID Gene Info
Arid5a
ENSMUSG00000037447.17 Arid5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid5amm39_v1_chr1_+_36346824_36346850-0.352.4e-03Click!

Activity profile of Arid5a motif

Sorted Z-values of Arid5a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_58645189 6.35 ENSMUST00000102755.4
ENSMUST00000230627.2
ENSMUST00000229923.2
Upp2
uridine phosphorylase 2
chr7_-_105249308 5.37 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr2_+_58644922 4.84 ENSMUST00000059102.13
Upp2
uridine phosphorylase 2
chr5_-_87074380 4.80 ENSMUST00000031183.3
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr2_+_61876956 3.29 ENSMUST00000112480.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_61876923 3.11 ENSMUST00000054484.15
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_61876806 2.95 ENSMUST00000102735.10
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr15_+_41573995 2.55 ENSMUST00000229769.2
Oxr1
oxidation resistance 1
chr2_-_79959178 2.05 ENSMUST00000102654.11
ENSMUST00000102655.10
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr3_+_75982890 1.72 ENSMUST00000160261.8
Fstl5
follistatin-like 5
chr1_+_133965228 1.63 ENSMUST00000162779.2
Fmod
fibromodulin
chr15_-_55421144 1.55 ENSMUST00000172387.8
Mrpl13
mitochondrial ribosomal protein L13
chr2_+_105505823 1.55 ENSMUST00000167211.9
ENSMUST00000111083.10
Pax6
paired box 6
chr2_-_79959802 1.24 ENSMUST00000102653.8
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr18_+_37637317 1.09 ENSMUST00000052179.8
Pcdhb20
protocadherin beta 20
chr4_+_43384320 0.98 ENSMUST00000136360.2
Rusc2
RUN and SH3 domain containing 2
chr14_+_58313964 0.91 ENSMUST00000166770.2
Fgf9
fibroblast growth factor 9
chr10_-_115197775 0.79 ENSMUST00000217848.2
Tmem19
transmembrane protein 19
chr10_-_115198093 0.78 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
Tmem19
transmembrane protein 19
chr9_+_20148415 0.76 ENSMUST00000086474.6
Olfr872
olfactory receptor 872
chrM_+_7758 0.71 ENSMUST00000082407.1
mt-Atp8
mitochondrially encoded ATP synthase 8
chrM_+_7779 0.67 ENSMUST00000082408.1
mt-Atp6
mitochondrially encoded ATP synthase 6
chr16_-_58583539 0.67 ENSMUST00000214139.2
Olfr172
olfactory receptor 172
chr3_-_146487102 0.56 ENSMUST00000005164.12
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr1_-_171885140 0.56 ENSMUST00000059794.4
Nhlh1
nescient helix loop helix 1
chr3_+_122298308 0.37 ENSMUST00000199358.2
Bcar3
breast cancer anti-estrogen resistance 3
chr10_+_52267702 0.35 ENSMUST00000067085.7
Nepn
nephrocan
chr11_-_58425662 0.28 ENSMUST00000213188.3
Olfr330
olfactory receptor 330
chr10_+_69369854 0.20 ENSMUST00000182557.8
Ank3
ankyrin 3, epithelial
chr10_-_129530155 0.20 ENSMUST00000204641.3
Olfr803
olfactory receptor 803
chrM_+_8603 0.15 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr10_+_129298547 0.11 ENSMUST00000077836.3
Olfr787
olfactory receptor 787
chr17_-_37627945 0.07 ENSMUST00000217590.2
Olfr102
olfactory receptor 102
chrX_-_133012600 0.04 ENSMUST00000033610.13
Nox1
NADPH oxidase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0018879 biphenyl metabolic process(GO:0018879)
0.8 5.4 GO:0015886 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 1.5 GO:0021918 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.3 9.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 11.2 GO:0009166 nucleotide catabolic process(GO:0009166)
0.1 0.9 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.3 GO:0097441 basilar dendrite(GO:0097441)
1.0 11.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.9 5.4 GO:0015232 heme transporter activity(GO:0015232)
0.4 9.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 3.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 4.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.5 GO:0070410 AT DNA binding(GO:0003680) co-SMAD binding(GO:0070410)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 5.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.5 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis