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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Arnt2

Z-value: 0.35

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Transcription factors associated with Arnt2

Gene Symbol Gene ID Gene Info
Arnt2
ENSMUSG00000015709.10 Arnt2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arnt2mm39_v1_chr7_-_84059170_840592100.754.4e-14Click!

Activity profile of Arnt2 motif

Sorted Z-values of Arnt2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Arnt2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_101353742 4.75 ENSMUST00000154120.9
ENSMUST00000106930.8
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr19_-_5148506 3.96 ENSMUST00000025805.8
Cnih2
cornichon family AMPA receptor auxiliary protein 2
chr7_-_45019984 3.88 ENSMUST00000003971.10
Lin7b
lin-7 homolog B (C. elegans)
chr19_+_23736205 2.83 ENSMUST00000025830.9
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr11_+_42310557 2.29 ENSMUST00000007797.10
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr19_+_22425534 1.94 ENSMUST00000235522.2
ENSMUST00000236372.2
ENSMUST00000238066.2
ENSMUST00000235780.2
ENSMUST00000236804.2
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr2_-_131404203 1.74 ENSMUST00000103184.4
Adra1d
adrenergic receptor, alpha 1d
chr2_-_33261498 1.69 ENSMUST00000113165.8
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr14_-_63781381 1.57 ENSMUST00000058679.7
Mtmr9
myotubularin related protein 9
chr2_-_33261411 1.47 ENSMUST00000131298.7
ENSMUST00000091039.5
ENSMUST00000042615.13
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr9_+_65278979 1.39 ENSMUST00000239433.2
Ubap1l
ubiquitin-associated protein 1-like
chr1_-_52856801 1.12 ENSMUST00000027271.9
Inpp1
inositol polyphosphate-1-phosphatase
chr5_-_135280063 1.07 ENSMUST00000062572.3
Fzd9
frizzled class receptor 9
chr1_-_52856662 0.99 ENSMUST00000162576.8
Inpp1
inositol polyphosphate-1-phosphatase
chr9_-_44231526 0.85 ENSMUST00000214602.2
ENSMUST00000065080.10
C2cd2l
C2 calcium-dependent domain containing 2-like
chr19_+_22425565 0.85 ENSMUST00000037901.14
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr5_+_88712840 0.83 ENSMUST00000196894.5
ENSMUST00000198965.5
Rufy3
RUN and FYVE domain containing 3
chr11_-_45835737 0.83 ENSMUST00000129820.8
Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr8_+_84627332 0.80 ENSMUST00000045393.15
ENSMUST00000132500.8
ENSMUST00000152978.8
Adgrl1
adhesion G protein-coupled receptor L1
chr10_+_11219117 0.60 ENSMUST00000069106.5
Epm2a
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr7_+_18810167 0.58 ENSMUST00000108479.2
Dmwd
dystrophia myotonica-containing WD repeat motif
chr4_+_123010035 0.57 ENSMUST00000102648.6
Oxct2b
3-oxoacid CoA transferase 2B
chr2_+_79085844 0.55 ENSMUST00000099972.5
Itga4
integrin alpha 4
chr11_+_107438751 0.55 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
Helz
helicase with zinc finger domain
chr7_+_18810097 0.44 ENSMUST00000032570.14
Dmwd
dystrophia myotonica-containing WD repeat motif
chr4_-_129534853 0.36 ENSMUST00000046425.16
ENSMUST00000133803.8
Txlna
taxilin alpha
chr2_+_91480460 0.34 ENSMUST00000111331.9
Arhgap1
Rho GTPase activating protein 1
chr1_-_59012579 0.33 ENSMUST00000173590.2
ENSMUST00000027186.12
Trak2
trafficking protein, kinesin binding 2
chr4_-_129534752 0.32 ENSMUST00000132217.8
ENSMUST00000130017.2
ENSMUST00000154105.8
Txlna
taxilin alpha
chr4_-_123217391 0.32 ENSMUST00000102640.2
Oxct2a
3-oxoacid CoA transferase 2A
chr7_+_130467486 0.21 ENSMUST00000120441.8
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr16_-_4238280 0.20 ENSMUST00000120080.8
Adcy9
adenylate cyclase 9
chr3_+_96604390 0.10 ENSMUST00000162778.3
ENSMUST00000064900.16
Pias3
protein inhibitor of activated STAT 3
chr11_+_43419586 0.10 ENSMUST00000050574.7
Ccnjl
cyclin J-like
chr1_+_74627445 0.07 ENSMUST00000113733.10
ENSMUST00000027358.11
Bcs1l
BCS1-like (yeast)
chr10_-_121933276 0.03 ENSMUST00000140299.3
Rxylt1
ribitol xylosyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.8 4.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.6 3.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 1.7 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.3 3.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 1.1 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.2 0.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 2.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.6 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.6 GO:0046959 habituation(GO:0046959)
0.1 0.3 GO:1903336 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.1 2.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.8 GO:0090129 calcium-mediated signaling using intracellular calcium source(GO:0035584) positive regulation of synapse maturation(GO:0090129)
0.0 0.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 0.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.8 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 5.6 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0097016 L27 domain binding(GO:0097016)
0.5 2.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.5 3.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 1.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 2.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 0.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.6 GO:2001070 starch binding(GO:2001070)
0.1 0.9 GO:0043559 insulin binding(GO:0043559)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 3.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.0 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway