ISMARA results: Ascl2

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Ascl2

Z-value: 1.75

Motif logo

Transcription factors associated with Ascl2

Gene Symbol	Gene ID	Gene Info
Ascl2 Ensembl NCBI MGI UniProt	ENSMUSG00000009248.7	Ascl2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ascl2	mm39_v1_chr7_-_142522995_142523006	0.23	5.4e-02	Click!

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chrX_-_111608339 Show fit	17.33	ENSMUST00000039887.4	Pof1b Ensembl NCBI MGI UniProt Show fit	premature ovarian failure 1B
chr5_-_98178811 Show fit	16.81	ENSMUST00000031281.14	Antxr2 Ensembl NCBI MGI UniProt Show fit	anthrax toxin receptor 2
chr16_+_57173456 Show fit	15.21	ENSMUST00000159816.8	Filip1l Ensembl NCBI MGI UniProt Show fit	filamin A interacting protein 1-like
chr7_+_142025575 Show fit	12.70	ENSMUST00000038946.9	Lsp1 Ensembl NCBI MGI UniProt Show fit	lymphocyte specific 1
chr12_-_103423472 Show fit	12.37	ENSMUST00000044687.7	Ifi27l2b Ensembl NCBI MGI UniProt Show fit	interferon, alpha-inducible protein 27 like 2B
chr13_-_63006176 Show fit	12.00	ENSMUST00000021907.9	Fbp2 Ensembl NCBI MGI UniProt Show fit	fructose bisphosphatase 2
chr12_-_114752425 Show fit	11.97	ENSMUST00000103510.2	Ighv1-26 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-26
chr5_+_136996713 Show fit	11.36	ENSMUST00000001790.6	Cldn15 Ensembl NCBI MGI UniProt Show fit	claudin 15
chr3_-_100396635 Show fit	10.29	ENSMUST00000061455.9	Tent5c Ensembl NCBI MGI UniProt Show fit	terminal nucleotidyltransferase 5C
chr7_+_142025817 Show fit	10.12	ENSMUST00000105966.2	Lsp1 Ensembl NCBI MGI UniProt Show fit	lymphocyte specific 1
chr11_+_62711057 Show fit	9.92	ENSMUST00000055006.12 ENSMUST00000072639.10	Trim16 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 16
chr4_-_43523745 Show fit	9.90	ENSMUST00000150592.2	Tpm2 Ensembl NCBI MGI UniProt Show fit	tropomyosin 2, beta
chr4_-_43523595 Show fit	9.32	ENSMUST00000107914.10	Tpm2 Ensembl NCBI MGI UniProt Show fit	tropomyosin 2, beta
chr11_+_69856222 Show fit	9.20	ENSMUST00000018713.13	Cldn7 Ensembl NCBI MGI UniProt Show fit	claudin 7
chr5_-_134975773 Show fit	9.13	ENSMUST00000051401.4	Cldn4 Ensembl NCBI MGI UniProt Show fit	claudin 4
chr15_+_101310283 Show fit	9.11	ENSMUST00000068904.9	Krt7 Ensembl NCBI MGI UniProt Show fit	keratin 7
chr10_-_128237087 Show fit	8.62	ENSMUST00000042666.13	Slc39a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 39 (metal ion transporter), member 5
chr2_+_153334710 Show fit	8.35	ENSMUST00000109783.2	4930404H24Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4930404H24 gene
chr6_-_69741999 Show fit	8.27	ENSMUST00000103365.3	Igkv12-46 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 12-46
chr9_-_71499628 Show fit	8.09	ENSMUST00000093823.8	Myzap Ensembl NCBI MGI UniProt Show fit	myocardial zonula adherens protein
chr15_-_74983786 Show fit	7.75	ENSMUST00000191451.2 ENSMUST00000100542.10	Ly6c2 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 6 complex, locus C2
chr7_+_43874854 Show fit	7.63	ENSMUST00000206144.2	Klk1 Ensembl NCBI MGI UniProt Show fit	kallikrein 1
chr2_-_179976458 Show fit	7.50	ENSMUST00000015771.3	Gata5 Ensembl NCBI MGI UniProt Show fit	GATA binding protein 5
chr2_-_147888816 Show fit	7.48	ENSMUST00000172928.2 ENSMUST00000047315.10	Foxa2 Ensembl NCBI MGI UniProt Show fit	forkhead box A2
chr9_-_71499547 Show fit	7.47	ENSMUST00000169573.8	Myzap Ensembl NCBI MGI UniProt Show fit	myocardial zonula adherens protein
chr4_-_141345549 Show fit	7.42	ENSMUST00000053263.9	Tmem82 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 82
chr7_+_27770655 Show fit	7.38	ENSMUST00000138392.8 ENSMUST00000076648.8	Fcgbp Ensembl NCBI MGI UniProt Show fit	Fc fragment of IgG binding protein
chr12_-_114878652 Show fit	7.36	ENSMUST00000103515.2	Ighv1-39 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-39
chr7_-_127593003 Show fit	7.34	ENSMUST00000033056.5	Pycard Ensembl NCBI MGI UniProt Show fit	PYD and CARD domain containing
chr1_+_177270101 Show fit	7.18	ENSMUST00000194319.2	Zbtb18 Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 18
chr19_+_6155804 Show fit	7.16	ENSMUST00000044451.4	Naaladl1 Ensembl NCBI MGI UniProt Show fit	N-acetylated alpha-linked acidic dipeptidase-like 1
chr11_+_99755302 Show fit	7.11	ENSMUST00000092694.4	Gm11559 Ensembl NCBI MGI UniProt Show fit	predicted gene 11559
chr4_-_133600308 Show fit	6.97	ENSMUST00000137486.3	Rps6ka1 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 1
chr4_-_43523388 Show fit	6.95	ENSMUST00000107913.10 ENSMUST00000030184.12	Tpm2 Ensembl NCBI MGI UniProt Show fit	tropomyosin 2, beta
chr6_-_69835868 Show fit	6.88	ENSMUST00000103369.2	Igkv12-41 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 12-41
chr11_+_62711295 Show fit	6.75	ENSMUST00000108703.2	Trim16 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 16
chr19_+_38384428 Show fit	6.75	ENSMUST00000054098.4	Slc35g1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 35, member G1
chr12_-_103409912 Show fit	6.70	ENSMUST00000055071.9	Ifi27l2a Ensembl NCBI MGI UniProt Show fit	interferon, alpha-inducible protein 27 like 2A
chr1_+_171246593 Show fit	6.64	ENSMUST00000171362.2	Tstd1 Ensembl NCBI MGI UniProt Show fit	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr9_-_45115381 Show fit	6.63	ENSMUST00000034599.15	Tmprss4 Ensembl NCBI MGI UniProt Show fit	transmembrane protease, serine 4
chr15_+_101936615 Show fit	6.58	ENSMUST00000023803.8	Krt18 Ensembl NCBI MGI UniProt Show fit	keratin 18
chr8_-_112417633 Show fit	6.51	ENSMUST00000034435.7	Ctrb1 Ensembl NCBI MGI UniProt Show fit	chymotrypsinogen B1
chr1_+_172327812 Show fit	6.50	ENSMUST00000192460.2	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chr2_+_122479770 Show fit	6.48	ENSMUST00000047498.15 ENSMUST00000110512.4	AA467197 Ensembl NCBI MGI UniProt Show fit	expressed sequence AA467197
chr7_-_44180700 Show fit	6.43	ENSMUST00000205506.2	Spib Ensembl NCBI MGI UniProt Show fit	Spi-B transcription factor (Spi-1/PU.1 related)
chrX_+_100492684 Show fit	6.16	ENSMUST00000033674.6	Itgb1bp2 Ensembl NCBI MGI UniProt Show fit	integrin beta 1 binding protein 2
chr5_+_91287448 Show fit	6.16	ENSMUST00000031325.6	Areg Ensembl NCBI MGI UniProt Show fit	amphiregulin
chr11_+_96820220 Show fit	6.14	ENSMUST00000062172.6	Prr15l Ensembl NCBI MGI UniProt Show fit	proline rich 15-like
chr11_+_117700479 Show fit	6.10	ENSMUST00000026649.14 ENSMUST00000177131.8 ENSMUST00000120928.2 ENSMUST00000175737.2 ENSMUST00000132298.2	Syngr2 Ensembl NCBI MGI UniProt Show fit Gm20708 Ensembl NCBI MGI UniProt Show fit	synaptogyrin 2 predicted gene 20708
chr6_-_68681962 Show fit	6.06	ENSMUST00000103330.2	Igkv10-94 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 10-94
chr6_+_135339543 Show fit	5.94	ENSMUST00000205156.3	Emp1 Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 1
chr5_-_98178834 Show fit	5.93	ENSMUST00000199088.2	Antxr2 Ensembl NCBI MGI UniProt Show fit	anthrax toxin receptor 2
chr16_+_57173632 Show fit	5.88	ENSMUST00000099667.3	Filip1l Ensembl NCBI MGI UniProt Show fit	filamin A interacting protein 1-like
chr7_+_3339059 Show fit	5.79	ENSMUST00000096744.8	Myadm Ensembl NCBI MGI UniProt Show fit	myeloid-associated differentiation marker
chr6_+_135339929 Show fit	5.72	ENSMUST00000032330.16	Emp1 Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 1
chr11_+_83007635 Show fit	5.71	ENSMUST00000037994.8	Slfn1 Ensembl NCBI MGI UniProt Show fit	schlafen 1
chr7_+_3339077 Show fit	5.64	ENSMUST00000203566.3	Myadm Ensembl NCBI MGI UniProt Show fit	myeloid-associated differentiation marker
chr7_-_80037153 Show fit	5.60	ENSMUST00000206728.2	Fes Ensembl NCBI MGI UniProt Show fit	feline sarcoma oncogene
chr1_-_133352115 Show fit	5.52	ENSMUST00000153799.8	Sox13 Ensembl NCBI MGI UniProt Show fit	SRY (sex determining region Y)-box 13
chr16_+_65612083 Show fit	5.52	ENSMUST00000168064.3	Vgll3 Ensembl NCBI MGI UniProt Show fit	vestigial like family member 3
chr11_+_121593219 Show fit	5.49	ENSMUST00000036742.14	Metrnl Ensembl NCBI MGI UniProt Show fit	meteorin, glial cell differentiation regulator-like
chr12_+_113104085 Show fit	5.47	ENSMUST00000200380.5	Crip2 Ensembl NCBI MGI UniProt Show fit	cysteine rich protein 2
chr16_+_65612394 Show fit	5.47	ENSMUST00000227997.2	Vgll3 Ensembl NCBI MGI UniProt Show fit	vestigial like family member 3
chr11_+_117740077 Show fit	5.43	ENSMUST00000081387.11	Birc5 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 5
chr14_+_34395845 Show fit	5.42	ENSMUST00000048263.14	Wapl Ensembl NCBI MGI UniProt Show fit	WAPL cohesin release factor
chr1_-_135846937 Show fit	5.39	ENSMUST00000027667.13	Pkp1 Ensembl NCBI MGI UniProt Show fit	plakophilin 1
chr1_-_156501860 Show fit	5.35	ENSMUST00000188964.7 ENSMUST00000190607.2 ENSMUST00000079625.11	Tor3a Ensembl NCBI MGI UniProt Show fit	torsin family 3, member A
chr5_+_35198853 Show fit	5.35	ENSMUST00000030985.10 ENSMUST00000202573.2	Hgfac Ensembl NCBI MGI UniProt Show fit	hepatocyte growth factor activator
chr3_+_106393348 Show fit	5.34	ENSMUST00000183271.2	Dennd2d Ensembl NCBI MGI UniProt Show fit	DENN/MADD domain containing 2D
chr12_-_113733922 Show fit	5.30	ENSMUST00000180013.3	Ighv2-9-1 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 2-9-1
chr6_-_52168675 Show fit	5.27	ENSMUST00000101395.3	Hoxa4 Ensembl NCBI MGI UniProt Show fit	homeobox A4
chr12_-_115916604 Show fit	5.19	ENSMUST00000196991.2	Ighv1-82 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-82
chr17_-_35285146 Show fit	5.13	ENSMUST00000174190.2 ENSMUST00000097337.8	Mpig6b Ensembl NCBI MGI UniProt Show fit	megakaryocyte and platelet inhibitory receptor G6b
chr12_-_115832846 Show fit	5.06	ENSMUST00000199373.2	Ighv1-78 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-78
chr12_-_113790741 Show fit	5.06	ENSMUST00000103457.3 ENSMUST00000192877.2	Ighv5-15 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 5-15
chr12_+_113103817 Show fit	5.02	ENSMUST00000084882.9	Crip2 Ensembl NCBI MGI UniProt Show fit	cysteine rich protein 2
chr1_+_40720731 Show fit	4.96	ENSMUST00000192345.2	Slc9a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr17_-_57535003 Show fit	4.96	ENSMUST00000177046.2 ENSMUST00000024988.15	C3 Ensembl NCBI MGI UniProt Show fit	complement component 3
chr11_-_99519057 Show fit	4.95	ENSMUST00000081007.7	Krtap4-1 Ensembl NCBI MGI UniProt Show fit	keratin associated protein 4-1
chr14_-_70761507 Show fit	4.95	ENSMUST00000022692.5	Sftpc Ensembl NCBI MGI UniProt Show fit	surfactant associated protein C
chr15_+_75027089 Show fit	4.94	ENSMUST00000190262.2	Ly6g Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 6 complex, locus G
chr2_-_174280811 Show fit	4.91	ENSMUST00000016400.9	Ctsz Ensembl NCBI MGI UniProt Show fit	cathepsin Z
chr1_-_167221344 Show fit	4.83	ENSMUST00000028005.3	Mgst3 Ensembl NCBI MGI UniProt Show fit	microsomal glutathione S-transferase 3
chr7_-_141023199 Show fit	4.82	ENSMUST00000106005.9	Pidd1 Ensembl NCBI MGI UniProt Show fit	p53 induced death domain protein 1
chr9_+_107784065 Show fit	4.77	ENSMUST00000035203.9	Mst1r Ensembl NCBI MGI UniProt Show fit	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr7_-_28246530 Show fit	4.75	ENSMUST00000239002.2 ENSMUST00000057974.4	Nccrp1 Ensembl NCBI MGI UniProt Show fit	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr1_-_52539395 Show fit	4.68	ENSMUST00000186764.7	Nab1 Ensembl NCBI MGI UniProt Show fit	Ngfi-A binding protein 1
chr4_-_46536088 Show fit	4.67	ENSMUST00000102924.3 ENSMUST00000046897.13	Trim14 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 14
chr1_-_135846858 Show fit	4.66	ENSMUST00000163260.8	Pkp1 Ensembl NCBI MGI UniProt Show fit	plakophilin 1
chr17_-_43813664 Show fit	4.63	ENSMUST00000024707.9 ENSMUST00000117137.8	Mep1a Ensembl NCBI MGI UniProt Show fit	meprin 1 alpha
chr8_+_96078886 Show fit	4.58	ENSMUST00000034243.7	Mmp15 Ensembl NCBI MGI UniProt Show fit	matrix metallopeptidase 15
chr6_+_127538268 Show fit	4.52	ENSMUST00000212051.2	Cracr2a Ensembl NCBI MGI UniProt Show fit	calcium release activated channel regulator 2A
chr9_-_66951151 Show fit	4.49	ENSMUST00000113696.8	Tpm1 Ensembl NCBI MGI UniProt Show fit	tropomyosin 1, alpha
chr7_+_43874752 Show fit	4.44	ENSMUST00000075162.5	Klk1 Ensembl NCBI MGI UniProt Show fit	kallikrein 1
chr9_-_71499594 Show fit	4.41	ENSMUST00000166112.2	Myzap Ensembl NCBI MGI UniProt Show fit	myocardial zonula adherens protein
chr16_+_78727829 Show fit	4.38	ENSMUST00000114216.2 ENSMUST00000069148.13 ENSMUST00000023568.14	Chodl Ensembl NCBI MGI UniProt Show fit	chondrolectin
chr9_-_66951025 Show fit	4.37	ENSMUST00000113695.8	Tpm1 Ensembl NCBI MGI UniProt Show fit	tropomyosin 1, alpha
chr16_-_36648586 Show fit	4.36	ENSMUST00000023537.6 ENSMUST00000114829.9	Eaf2 Ensembl NCBI MGI UniProt Show fit	ELL associated factor 2
chr13_+_54849268 Show fit	4.34	ENSMUST00000037145.8	Cdhr2 Ensembl NCBI MGI UniProt Show fit	cadherin-related family member 2
chr2_-_25086810 Show fit	4.33	ENSMUST00000081869.7	Tor4a Ensembl NCBI MGI UniProt Show fit	torsin family 4, member A
chr17_+_87590308 Show fit	4.32	ENSMUST00000041110.12 ENSMUST00000125875.8	Ttc7 Ensembl NCBI MGI UniProt Show fit	tetratricopeptide repeat domain 7
chr17_+_48096628 Show fit	4.29	ENSMUST00000024786.14	Tfeb Ensembl NCBI MGI UniProt Show fit	transcription factor EB
chr2_+_167380112 Show fit	4.28	ENSMUST00000052631.8	Snai1 Ensembl NCBI MGI UniProt Show fit	snail family zinc finger 1
chr11_+_33913013 Show fit	4.27	ENSMUST00000020362.3	Kcnmb1 Ensembl NCBI MGI UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr11_+_98337655 Show fit	4.26	ENSMUST00000019456.5	Grb7 Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 7
chr7_+_89053562 Show fit	4.25	ENSMUST00000058755.5	Fzd4 Ensembl NCBI MGI UniProt Show fit	frizzled class receptor 4
chr11_-_106240215 Show fit	4.22	ENSMUST00000021056.8	Scn4a Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type IV, alpha
chr5_+_64317550 Show fit	4.21	ENSMUST00000101195.9	Tbc1d1 Ensembl NCBI MGI UniProt Show fit	TBC1 domain family, member 1
chr9_+_110867807 Show fit	4.20	ENSMUST00000197575.2	Ltf Ensembl NCBI MGI UniProt Show fit	lactotransferrin
chr5_-_107873883 Show fit	4.18	ENSMUST00000159263.3	Gfi1 Ensembl NCBI MGI UniProt Show fit	growth factor independent 1 transcription repressor
chr4_-_131695135 Show fit	4.18	ENSMUST00000146443.8 ENSMUST00000135579.8	Epb41 Ensembl NCBI MGI UniProt Show fit	erythrocyte membrane protein band 4.1
chr2_+_164245114 Show fit	4.17	ENSMUST00000017151.2	Rbpjl Ensembl NCBI MGI UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region-like
chr18_+_64473091 Show fit	4.16	ENSMUST00000175965.10	Onecut2 Ensembl NCBI MGI UniProt Show fit	one cut domain, family member 2
chr9_+_44893077 Show fit	4.15	ENSMUST00000034602.9	Cd3d Ensembl NCBI MGI UniProt Show fit	CD3 antigen, delta polypeptide
chr14_-_56181993 Show fit	4.14	ENSMUST00000022834.7 ENSMUST00000226280.2	Cma1 Ensembl NCBI MGI UniProt Show fit	chymase 1, mast cell
chr19_-_41373526 Show fit	4.08	ENSMUST00000059672.9	Pik3ap1 Ensembl NCBI MGI UniProt Show fit	phosphoinositide-3-kinase adaptor protein 1
chr6_+_70680515 Show fit	4.05	ENSMUST00000103404.2	Igkv3-1 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 3-1
chr18_-_32692967 Show fit	4.01	ENSMUST00000174000.2 ENSMUST00000174459.2	Gypc Ensembl NCBI MGI UniProt Show fit	glycophorin C
chr7_-_80037622 Show fit	3.94	ENSMUST00000206698.2	Fes Ensembl NCBI MGI UniProt Show fit	feline sarcoma oncogene
chr4_-_63965161 Show fit	3.90	ENSMUST00000107377.10	Tnc Ensembl NCBI MGI UniProt Show fit	tenascin C
chr7_+_44866095 Show fit	3.88	ENSMUST00000209437.2	Tead2 Ensembl NCBI MGI UniProt Show fit	TEA domain family member 2
chr12_+_79177523 Show fit	3.87	ENSMUST00000021550.7	Arg2 Ensembl NCBI MGI UniProt Show fit	arginase type II
chr11_+_99805555 Show fit	3.87	ENSMUST00000105053.2	Gm11565 Ensembl NCBI MGI UniProt Show fit	predicted gene 11565
chr5_-_100867520 Show fit	3.87	ENSMUST00000112908.2 ENSMUST00000045617.15	Hpse Ensembl NCBI MGI UniProt Show fit	heparanase
chr15_-_89263448 Show fit	3.85	ENSMUST00000049968.9	Odf3b Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3B
chr12_+_71063431 Show fit	3.84	ENSMUST00000125125.2	Arid4a Ensembl NCBI MGI UniProt Show fit	AT rich interactive domain 4A (RBP1-like)
chr8_-_41827639 Show fit	3.83	ENSMUST00000034000.15 ENSMUST00000143057.2	Asah1 Ensembl NCBI MGI UniProt Show fit	N-acylsphingosine amidohydrolase 1
chr5_-_66330394 Show fit	3.82	ENSMUST00000201544.4	Rbm47 Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein 47
chr7_-_45173193 Show fit	3.80	ENSMUST00000211212.2	Ppp1r15a Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 15A
chr7_+_75105282 Show fit	3.79	ENSMUST00000207750.2 ENSMUST00000166315.7	Akap13 Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein 13
chr2_-_25086770 Show fit	3.79	ENSMUST00000142857.2 ENSMUST00000137920.2	Tor4a Ensembl NCBI MGI UniProt Show fit	torsin family 4, member A
chr11_+_83067429 Show fit	3.76	ENSMUST00000215472.2	Slfn4 Ensembl NCBI MGI UniProt Show fit	schlafen 4
chr2_+_35172392 Show fit	3.76	ENSMUST00000028239.8	Gsn Ensembl NCBI MGI UniProt Show fit	gelsolin
chr5_-_28415020 Show fit	3.75	ENSMUST00000118882.2	Cnpy1 Ensembl NCBI MGI UniProt Show fit	canopy FGF signaling regulator 1
chr2_-_60383647 Show fit	3.75	ENSMUST00000112525.5	Pla2r1 Ensembl NCBI MGI UniProt Show fit	phospholipase A2 receptor 1
chr18_-_10182007 Show fit	3.71	ENSMUST00000067947.7	Rock1 Ensembl NCBI MGI UniProt Show fit	Rho-associated coiled-coil containing protein kinase 1
chr1_+_174000304 Show fit	3.71	ENSMUST00000027817.8	Spta1 Ensembl NCBI MGI UniProt Show fit	spectrin alpha, erythrocytic 1
chr7_+_142014546 Show fit	3.66	ENSMUST00000105968.8 ENSMUST00000018963.11 ENSMUST00000105967.8	Lsp1 Ensembl NCBI MGI UniProt Show fit	lymphocyte specific 1
chr8_-_71834543 Show fit	3.66	ENSMUST00000002466.9	Nr2f6 Ensembl NCBI MGI UniProt Show fit	nuclear receptor subfamily 2, group F, member 6
chr4_-_123236596 Show fit	3.63	ENSMUST00000102641.10	Bmp8a Ensembl NCBI MGI UniProt Show fit	bone morphogenetic protein 8a
chr15_-_89263790 Show fit	3.60	ENSMUST00000238996.2	Odf3b Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3B
chr5_+_123153072 Show fit	3.58	ENSMUST00000051016.5 ENSMUST00000121652.8	Orai1 Ensembl NCBI MGI UniProt Show fit	ORAI calcium release-activated calcium modulator 1
chr6_+_68495964 Show fit	3.58	ENSMUST00000199510.5 ENSMUST00000103325.3	Igkv14-100 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 14-100
chr11_+_117740111 Show fit	3.58	ENSMUST00000093906.5	Birc5 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 5
chr3_+_108272205 Show fit	3.54	ENSMUST00000090563.7	Mybphl Ensembl NCBI MGI UniProt Show fit	myosin binding protein H-like
chr10_+_75729237 Show fit	3.53	ENSMUST00000009236.6 ENSMUST00000217811.2	Derl3 Ensembl NCBI MGI UniProt Show fit	Der1-like domain family, member 3
chr19_+_7034149 Show fit	3.50	ENSMUST00000040261.7	Macrod1 Ensembl NCBI MGI UniProt Show fit	mono-ADP ribosylhydrolase 1
chr19_+_37423198 Show fit	3.50	ENSMUST00000025944.9	Hhex Ensembl NCBI MGI UniProt Show fit	hematopoietically expressed homeobox
chr6_+_112436466 Show fit	3.50	ENSMUST00000075477.8	Cav3 Ensembl NCBI MGI UniProt Show fit	caveolin 3
chr10_+_34359395 Show fit	3.48	ENSMUST00000019913.15	Frk Ensembl NCBI MGI UniProt Show fit	fyn-related kinase
chr9_+_107852733 Show fit	3.46	ENSMUST00000035216.11	Uba7 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like modifier activating enzyme 7
chr17_-_45906768 Show fit	3.45	ENSMUST00000164618.8 ENSMUST00000097317.10 ENSMUST00000170113.8	Slc29a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 29 (nucleoside transporters), member 1
chr11_+_98798627 Show fit	3.43	ENSMUST00000092706.13	Cdc6 Ensembl NCBI MGI UniProt Show fit	cell division cycle 6
chr4_-_147894245 Show fit	3.43	ENSMUST00000105734.10 ENSMUST00000176201.2	Zfp984 Ensembl NCBI MGI UniProt Show fit Gm20707 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 984 predicted gene 20707
chr7_+_44866635 Show fit	3.43	ENSMUST00000097216.5 ENSMUST00000209343.2 ENSMUST00000209678.2	Tead2 Ensembl NCBI MGI UniProt Show fit	TEA domain family member 2
chr8_-_106198112 Show fit	3.42	ENSMUST00000014990.13	Tppp3 Ensembl NCBI MGI UniProt Show fit	tubulin polymerization-promoting protein family member 3
chr4_-_132990362 Show fit	3.35	ENSMUST00000105908.10 ENSMUST00000030674.8	Sytl1 Ensembl NCBI MGI UniProt Show fit	synaptotagmin-like 1
chr15_-_89263128 Show fit	3.35	ENSMUST00000227834.2	Odf3b Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3B
chr7_-_103964662 Show fit	3.34	ENSMUST00000106837.8 ENSMUST00000106839.9 ENSMUST00000070943.7	Trim12a Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 12A
chr16_+_48637219 Show fit	3.33	ENSMUST00000023328.8	Retnlb Ensembl NCBI MGI UniProt Show fit	resistin like beta
chr7_-_127805518 Show fit	3.33	ENSMUST00000033049.9	Cox6a2 Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit 6A2
chr5_-_106606032 Show fit	3.32	ENSMUST00000086795.8	Barhl2 Ensembl NCBI MGI UniProt Show fit	BarH like homeobox 2
chr15_+_102008829 Show fit	3.32	ENSMUST00000228958.2	Tns2 Ensembl NCBI MGI UniProt Show fit	tensin 2
chr4_-_133599616 Show fit	3.31	ENSMUST00000157067.9	Rps6ka1 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 1
chr11_+_45871135 Show fit	3.30	ENSMUST00000049038.4	Sox30 Ensembl NCBI MGI UniProt Show fit	SRY (sex determining region Y)-box 30
chr7_+_107264518 Show fit	3.28	ENSMUST00000239294.2	Ppfibp2 Ensembl NCBI MGI UniProt Show fit	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_34359513 Show fit	3.28	ENSMUST00000170771.3	Frk Ensembl NCBI MGI UniProt Show fit	fyn-related kinase
chr12_-_113386312 Show fit	3.24	ENSMUST00000177715.8 ENSMUST00000103426.3	Ighm Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy constant mu
chr7_-_79765042 Show fit	3.23	ENSMUST00000206714.2 ENSMUST00000107384.10	Idh2 Ensembl NCBI MGI UniProt Show fit	isocitrate dehydrogenase 2 (NADP+), mitochondrial
chrX_-_166047275 Show fit	3.23	ENSMUST00000112170.2	Tlr8 Ensembl NCBI MGI UniProt Show fit	toll-like receptor 8
chr11_+_61099447 Show fit	3.23	ENSMUST00000108716.8 ENSMUST00000019246.4	Aldh3a1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase family 3, subfamily A1
chr10_-_128796834 Show fit	3.20	ENSMUST00000026398.5	Mettl7b Ensembl NCBI MGI UniProt Show fit	methyltransferase like 7B
chr9_-_114673158 Show fit	3.19	ENSMUST00000047013.4	Cmtm8 Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 8
chr15_-_101588714 Show fit	3.19	ENSMUST00000023786.7	Krt6b Ensembl NCBI MGI UniProt Show fit	keratin 6B
chr4_-_137157824 Show fit	3.19	ENSMUST00000102522.5	Cela3b Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like elastase family, member 3B
chr13_-_92024994 Show fit	3.18	ENSMUST00000022122.4	Ckmt2 Ensembl NCBI MGI UniProt Show fit	creatine kinase, mitochondrial 2
chr19_-_45548942 Show fit	3.18	ENSMUST00000026239.7	Poll Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), lambda
chr15_-_75760602 Show fit	3.17	ENSMUST00000184858.2	Mroh6 Ensembl NCBI MGI UniProt Show fit	maestro heat-like repeat family member 6
chr7_+_78563964 Show fit	3.17	ENSMUST00000120331.4	Isg20 Ensembl NCBI MGI UniProt Show fit	interferon-stimulated protein
chr11_+_98555167 Show fit	3.15	ENSMUST00000017348.3	Gsdma Ensembl NCBI MGI UniProt Show fit	gasdermin A
chr2_+_127696548 Show fit	3.14	ENSMUST00000028859.8	Acoxl Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A oxidase-like
chr19_-_41836514 Show fit	3.12	ENSMUST00000059231.4	Frat2 Ensembl NCBI MGI UniProt Show fit	frequently rearranged in advanced T cell lymphomas 2
chr7_-_103937301 Show fit	3.12	ENSMUST00000098179.9	Trim5 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 5
chr15_-_74855264 Show fit	3.11	ENSMUST00000023250.11 ENSMUST00000166694.2	Ly6i Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 6 complex, locus I
chr2_-_92201342 Show fit	3.11	ENSMUST00000176810.8 ENSMUST00000090582.11 ENSMUST00000068586.13	Large2 Ensembl NCBI MGI UniProt Show fit	LARGE xylosyl- and glucuronyltransferase 2
chr18_+_32055339 Show fit	3.11	ENSMUST00000233994.2	Lims2 Ensembl NCBI MGI UniProt Show fit	LIM and senescent cell antigen like domains 2
chr6_+_125326662 Show fit	3.10	ENSMUST00000032491.15	Tnfrsf1a Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 1a
chr19_-_6014210 Show fit	3.10	ENSMUST00000025752.15 ENSMUST00000165143.3	Pola2 Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), alpha 2
chr5_+_137639538 Show fit	3.09	ENSMUST00000177466.8 ENSMUST00000166099.3	Sap25 Ensembl NCBI MGI UniProt Show fit	sin3 associated polypeptide
chr15_-_89263466 Show fit	3.09	ENSMUST00000228111.2	Odf3b Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3B
chr5_+_87148697 Show fit	3.08	ENSMUST00000031186.9	Ugt2b35 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B35
chr9_-_66950991 Show fit	3.05	ENSMUST00000113689.8 ENSMUST00000113684.8	Tpm1 Ensembl NCBI MGI UniProt Show fit	tropomyosin 1, alpha
chr2_+_33106062 Show fit	3.04	ENSMUST00000004208.7	Angptl2 Ensembl NCBI MGI UniProt Show fit	angiopoietin-like 2
chr12_-_113680723 Show fit	3.02	ENSMUST00000179657.2	Ighv2-6 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 2-6
chr1_+_87254729 Show fit	3.00	ENSMUST00000172794.8 ENSMUST00000164992.9 ENSMUST00000173173.8	Gigyf2 Ensembl NCBI MGI UniProt Show fit	GRB10 interacting GYF protein 2
chr16_+_93629009 Show fit	2.99	ENSMUST00000044068.10 ENSMUST00000202261.5 ENSMUST00000201097.3	Morc3 Ensembl NCBI MGI UniProt Show fit	microrchidia 3
chr19_-_57185988 Show fit	2.98	ENSMUST00000099294.9	Ablim1 Ensembl NCBI MGI UniProt Show fit	actin-binding LIM protein 1
chr12_-_115410489 Show fit	2.96	ENSMUST00000194581.2	Ighv1-62-2 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-62-2
chr7_+_78564062 Show fit	2.95	ENSMUST00000205981.2	Isg20 Ensembl NCBI MGI UniProt Show fit	interferon-stimulated protein
chr11_-_115426618 Show fit	2.93	ENSMUST00000121185.8 ENSMUST00000117589.8	Sumo2 Ensembl NCBI MGI UniProt Show fit	small ubiquitin-like modifier 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	12.0	GO:0046351	disaccharide biosynthetic process(GO:0046351)
2.6	15.6	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
2.5	7.5	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
2.4	7.3	GO:0002582	myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
1.9	5.7	GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
1.7	8.6	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
1.6	10.9	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957)
1.5	4.6	GO:0061300	cerebellum vasculature development(GO:0061300)
1.5	6.2	GO:0060598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.4	10.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
1.4	11.4	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.4	4.3	GO:1903413	response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
1.4	17.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.4	5.4	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.3	3.9	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
1.3	9.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
1.3	3.8	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.2	5.0	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
1.2	3.5	GO:0098583	mastication(GO:0071626) learned vocalization behavior(GO:0098583)
1.1	10.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
1.1	3.2	GO:0002344	peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.1	3.2	GO:1904464	regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773)
1.1	4.3	GO:0009816	defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
1.1	7.5	GO:0015862	uridine transport(GO:0015862)
1.1	4.2	GO:0044010	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.0	4.1	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
1.0	6.1	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.0	3.9	GO:0014012	peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
1.0	6.8	GO:1990034	calcium ion export from cell(GO:1990034)
1.0	2.9	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
0.9	10.4	GO:0035754	B cell chemotaxis(GO:0035754)
0.9	3.8	GO:0097017	renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.9	2.8	GO:0006740	NADPH regeneration(GO:0006740)
0.9	4.3	GO:1904970	brush border assembly(GO:1904970)
0.8	2.5	GO:0019542	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.8	2.5	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.8	3.9	GO:0090467	regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.7	3.7	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.7	2.9	GO:2000832	testosterone secretion(GO:0035936) negative regulation of steroid hormone secretion(GO:2000832) regulation of testosterone secretion(GO:2000843)
0.7	2.2	GO:0002851	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.7	3.5	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.7	2.1	GO:0032416	negative regulation of sodium:proton antiporter activity(GO:0032416)
0.7	4.7	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.7	2.7	GO:0045659	negative regulation of neutrophil differentiation(GO:0045659)
0.7	2.0	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.6	3.9	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.6	1.9	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.6	6.2	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.6	3.7	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.6	2.5	GO:0090472	dibasic protein processing(GO:0090472)
0.6	1.8	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.6	1.8	GO:0070318	myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.6	1.8	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.6	3.5	GO:0061017	hepatoblast differentiation(GO:0061017)
0.6	1.8	GO:0051542	elastin biosynthetic process(GO:0051542)
0.6	4.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.6	2.3	GO:0072190	ureter urothelium development(GO:0072190)
0.6	4.5	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.6	2.3	GO:0046381	CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.6	3.3	GO:0018094	protein polyglycylation(GO:0018094)
0.5	1.6	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.5	4.9	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.5	3.2	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.5	3.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.5	4.2	GO:0015871	choline transport(GO:0015871)
0.5	3.5	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.5	3.5	GO:1904180	negative regulation of membrane depolarization(GO:1904180)
0.5	4.3	GO:0040031	snRNA modification(GO:0040031)
0.5	3.8	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.5	5.6	GO:0061113	pancreas morphogenesis(GO:0061113)
0.5	9.2	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.5	1.4	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.5	5.0	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4	1.8	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.4	10.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.4	1.3	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.4	3.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.4	1.3	GO:0019389	glucuronoside metabolic process(GO:0019389)
0.4	3.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.4	9.4	GO:0014850	response to muscle activity(GO:0014850)
0.4	0.8	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.4	2.8	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4	4.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.4	3.5	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.4	11.7	GO:0032060	bleb assembly(GO:0032060)
0.4	2.6	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4	22.9	GO:1901998	toxin transport(GO:1901998)
0.4	2.6	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.4	4.4	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4	9.5	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3	1.0	GO:0061723	glycophagy(GO:0061723)
0.3	2.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3	1.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3	1.7	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.3	4.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.3	7.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.3	5.3	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.3	2.3	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.3	2.6	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.3	50.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.3	1.3	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3	3.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.3	3.7	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.3	5.6	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3	4.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.3	1.2	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3	3.8	GO:0016554	cytidine to uridine editing(GO:0016554)
0.3	1.2	GO:0072186	lactic acid secretion(GO:0046722) metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3	0.9	GO:0000066	mitochondrial ornithine transport(GO:0000066)
0.3	19.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.3	3.8	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
0.3	1.6	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.3	2.6	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.3	6.3	GO:0061436	establishment of skin barrier(GO:0061436)
0.3	1.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.3	1.8	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.3	6.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2	1.5	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2	1.7	GO:0042359	vitamin D metabolic process(GO:0042359)
0.2	1.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	1.0	GO:0046340	termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.2	1.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	2.1	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.2	4.2	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2	7.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.2	1.4	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.2	0.9	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	4.2	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2	3.6	GO:0002024	diet induced thermogenesis(GO:0002024)
0.2	11.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.2	9.2	GO:0006270	DNA replication initiation(GO:0006270)
0.2	3.5	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.2	3.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	3.1	GO:0009650	UV protection(GO:0009650)
0.2	0.8	GO:0006447	regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.2	2.7	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.6	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2	2.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2	2.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	1.7	GO:0006004	fucose metabolic process(GO:0006004)
0.2	4.3	GO:0034063	stress granule assembly(GO:0034063)
0.2	5.0	GO:0072663	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2	0.4	GO:0051464	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) positive regulation of cortisol secretion(GO:0051464)
0.2	3.7	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2	1.8	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2	2.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.2	0.5	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.2	3.8	GO:0008272	sulfate transport(GO:0008272)
0.2	1.5	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.2	2.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	2.7	GO:0072189	ureter development(GO:0072189)
0.2	1.3	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2	1.3	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.2	6.4	GO:0030225	macrophage differentiation(GO:0030225)
0.2	3.6	GO:0002115	store-operated calcium entry(GO:0002115)
0.2	1.6	GO:0060056	mammary gland involution(GO:0060056)
0.2	3.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.2	0.6	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.1	4.6	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.6	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.9	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	2.2	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1	1.0	GO:0033045	regulation of sister chromatid segregation(GO:0033045)
0.1	0.6	GO:0090345	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1	1.8	GO:0060033	anatomical structure regression(GO:0060033)
0.1	1.7	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	2.0	GO:0090527	actin filament reorganization(GO:0090527)
0.1	1.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.1	6.0	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.1	2.8	GO:0021670	lateral ventricle development(GO:0021670)
0.1	1.2	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	2.3	GO:0032570	response to progesterone(GO:0032570)
0.1	3.3	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.1	2.7	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	2.1	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	1.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	1.6	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.1	1.1	GO:0036065	fucosylation(GO:0036065)
0.1	0.4	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.6	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	1.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.3	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	1.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	1.9	GO:0046415	urate metabolic process(GO:0046415)
0.1	1.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	1.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.1	3.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	1.0	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	1.0	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	4.8	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	0.3	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	1.7	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	2.7	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	0.5	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	1.4	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.1	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	1.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) cellular response to morphine(GO:0071315)
0.1	3.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.1	1.8	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	0.7	GO:0015879	carnitine transport(GO:0015879)
0.1	0.7	GO:0006573	valine metabolic process(GO:0006573)
0.1	16.2	GO:0002377	immunoglobulin production(GO:0002377)
0.1	0.5	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.1	2.4	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.8	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.2	GO:0007225	patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1	4.9	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	1.4	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	0.1	GO:0003195	tricuspid valve formation(GO:0003195)
0.1	0.8	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	1.2	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	0.2	GO:0043418	homocysteine catabolic process(GO:0043418)
0.1	1.0	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1	1.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.2	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	5.3	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	1.8	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	2.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	2.3	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.6	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	2.2	GO:0001709	cell fate determination(GO:0001709)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.0	1.6	GO:0046686	response to cadmium ion(GO:0046686)
0.0	2.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.8	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.2	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	2.0	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	1.4	GO:0070232	regulation of T cell apoptotic process(GO:0070232)
0.0	1.0	GO:0007602	phototransduction(GO:0007602)
0.0	0.3	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.7	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	10.2	GO:0009615	response to virus(GO:0009615)
0.0	0.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.0	2.6	GO:0007569	cell aging(GO:0007569)
0.0	2.8	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	1.9	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.2	GO:0051715	cytolysis in other organism(GO:0051715)
0.0	3.5	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	1.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.8	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	1.9	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	1.1	GO:0043171	peptide catabolic process(GO:0043171)
0.0	1.0	GO:0009072	aromatic amino acid family metabolic process(GO:0009072)
0.0	1.0	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.7	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	1.3	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	6.4	GO:0051302	regulation of cell division(GO:0051302)
0.0	1.5	GO:0050909	sensory perception of taste(GO:0050909)
0.0	2.6	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.1	GO:0021506	anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0	1.3	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	3.3	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.9	GO:0051384	response to glucocorticoid(GO:0051384)
0.0	0.5	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	1.9	GO:0008203	cholesterol metabolic process(GO:0008203)
0.0	1.9	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0040016	negative regulation of superoxide anion generation(GO:0032929) embryonic cleavage(GO:0040016) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.7	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.9	GO:0001889	liver development(GO:0001889)
0.0	0.1	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	2.1	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	3.4	GO:0007015	actin filament organization(GO:0007015)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	41.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
2.3	9.0	GO:0031021	interphase microtubule organizing center(GO:0031021)
1.8	7.3	GO:0097169	AIM2 inflammasome complex(GO:0097169)
1.8	7.3	GO:0071149	TEAD-2-YAP complex(GO:0071149)
1.5	4.4	GO:0032783	ELL-EAF complex(GO:0032783)
0.8	5.5	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.8	26.9	GO:0030057	desmosome(GO:0030057)
0.7	8.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.7	4.2	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.5	3.7	GO:0032437	cuticular plate(GO:0032437)
0.5	2.1	GO:0005608	laminin-3 complex(GO:0005608)
0.5	9.8	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.5	3.5	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.5	1.9	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5	15.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.5	5.4	GO:0008278	cohesin complex(GO:0008278)
0.4	53.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.4	4.3	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4	4.9	GO:0097208	alveolar lamellar body(GO:0097208)
0.4	16.1	GO:0045095	keratin filament(GO:0045095)
0.4	3.8	GO:0030478	actin cap(GO:0030478)
0.3	3.1	GO:1990462	omegasome(GO:1990462)
0.3	2.9	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.3	34.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.3	3.4	GO:0097427	microtubule bundle(GO:0097427)
0.3	3.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.3	3.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.3	17.4	GO:0030863	cortical cytoskeleton(GO:0030863)
0.2	1.1	GO:0043293	apoptosome(GO:0043293)
0.2	3.8	GO:1990635	proximal dendrite(GO:1990635)
0.2	1.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2	1.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	1.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	2.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	4.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.2	2.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.2	1.1	GO:1990246	uniplex complex(GO:1990246)
0.1	3.5	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.1	3.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	19.3	GO:0016605	PML body(GO:0016605)
0.1	11.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	0.4	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.1	1.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	1.3	GO:0031045	dense core granule(GO:0031045)
0.1	8.9	GO:0045171	intercellular bridge(GO:0045171)
0.1	2.1	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.5	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	1.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	4.0	GO:0051233	spindle midzone(GO:0051233)
0.1	0.5	GO:0071817	MMXD complex(GO:0071817)
0.1	2.8	GO:0031528	microvillus membrane(GO:0031528)
0.1	6.0	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	11.9	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	4.9	GO:0099738	cell cortex region(GO:0099738)
0.1	2.3	GO:0005652	nuclear lamina(GO:0005652)
0.1	1.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	2.9	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	19.7	GO:0031012	extracellular matrix(GO:0031012)
0.1	3.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	0.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.4	GO:0035339	SPOTS complex(GO:0035339)
0.1	7.3	GO:0031594	neuromuscular junction(GO:0031594)
0.1	2.0	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	2.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	1.0	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	1.4	GO:0005605	basal lamina(GO:0005605)
0.1	0.7	GO:0071141	SMAD protein complex(GO:0071141)
0.1	2.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	1.0	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	1.4	GO:0005614	interstitial matrix(GO:0005614)
0.1	35.1	GO:0005667	transcription factor complex(GO:0005667)
0.1	6.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	2.7	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	4.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	21.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.7	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	2.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	2.1	GO:0032420	stereocilium(GO:0032420)
0.0	0.7	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	23.1	GO:0005925	focal adhesion(GO:0005925)
0.0	0.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	6.5	GO:0005938	cell cortex(GO:0005938)
0.0	2.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0043291	RAVE complex(GO:0043291)
0.0	1.0	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	3.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	3.8	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	9.0	GO:0016324	apical plasma membrane(GO:0016324)
0.0	2.5	GO:0005903	brush border(GO:0005903)
0.0	6.9	GO:0005819	spindle(GO:0005819)
0.0	2.4	GO:0005643	nuclear pore(GO:0005643)
0.0	3.5	GO:0072562	blood microparticle(GO:0072562)
0.0	2.8	GO:0005930	axoneme(GO:0005930)
0.0	0.6	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.9	GO:0016235	aggresome(GO:0016235)
0.0	0.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	1.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	2.3	GO:0001726	ruffle(GO:0001726)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	27.6	GO:0005615	extracellular space(GO:0005615)
0.0	0.9	GO:0045177	apical part of cell(GO:0045177)
0.0	0.7	GO:0034707	chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	7.3	GO:0032090	Pyrin domain binding(GO:0032090)
1.9	7.5	GO:0047016	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.5	4.6	GO:0070773	protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
1.5	5.8	GO:0045159	myosin II binding(GO:0045159)
1.3	16.7	GO:0019966	interleukin-1 binding(GO:0019966)
1.2	6.1	GO:0008859	exoribonuclease II activity(GO:0008859)
1.0	3.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.8	2.5	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8	3.2	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.8	7.8	GO:0045545	syndecan binding(GO:0045545)
0.8	12.3	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.8	3.1	GO:0004096	catalase activity(GO:0004096)
0.8	2.3	GO:0030338	CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.7	5.9	GO:0017040	ceramidase activity(GO:0017040)
0.7	2.9	GO:0008160	protein tyrosine phosphatase activator activity(GO:0008160)
0.7	2.1	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.7	3.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.7	46.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.6	2.6	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.6	3.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6	1.8	GO:0016015	morphogen activity(GO:0016015)
0.6	2.9	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.6	1.7	GO:0015928	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.6	3.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.6	2.2	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.5	2.5	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.5	5.0	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.5	2.0	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.5	1.0	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
0.5	1.9	GO:0016822	oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5	63.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.5	1.4	GO:0047936	glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.5	3.2	GO:0004111	creatine kinase activity(GO:0004111)
0.5	1.4	GO:0004326	tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.4	1.3	GO:0015152	glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.4	1.3	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4	4.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.4	1.7	GO:0004995	tachykinin receptor activity(GO:0004995)
0.4	1.6	GO:0031708	endothelin B receptor binding(GO:0031708)
0.4	1.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.4	4.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4	1.8	GO:0070012	oligopeptidase activity(GO:0070012)
0.4	3.2	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3	2.8	GO:0051425	PTB domain binding(GO:0051425)
0.3	10.0	GO:0005521	lamin binding(GO:0005521)
0.3	3.8	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.3	2.0	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	1.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.3	9.8	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3	2.3	GO:0030549	acetylcholine receptor activator activity(GO:0030549)
0.3	3.7	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.3	2.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.3	3.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.3	1.3	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3	1.2	GO:0051435	BH4 domain binding(GO:0051435)
0.3	7.3	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.3	3.6	GO:0070700	BMP receptor binding(GO:0070700)
0.3	18.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3	5.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.3	3.5	GO:0071253	connexin binding(GO:0071253)
0.3	8.0	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.3	1.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.3	6.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	3.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.3	0.8	GO:0004686	elongation factor-2 kinase activity(GO:0004686)
0.2	1.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	9.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	3.6	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	0.7	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2	1.6	GO:0070404	NADH binding(GO:0070404)
0.2	0.7	GO:0035500	MH2 domain binding(GO:0035500)
0.2	7.1	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.2	12.1	GO:0004180	carboxypeptidase activity(GO:0004180)
0.2	3.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	2.8	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2	3.8	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.2	2.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	38.6	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2	47.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	0.6	GO:0051538	iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2	2.9	GO:0031386	protein tag(GO:0031386)
0.2	3.1	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.7	GO:0047710	bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2	0.9	GO:0043546	molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.2	4.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	1.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	4.1	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2	2.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	1.4	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.2	3.7	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	6.5	GO:0070064	proline-rich region binding(GO:0070064)
0.2	2.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	3.9	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2	1.9	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2	1.7	GO:0048101	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	7.9	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.2	3.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	4.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.6	GO:0016675	oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.1	0.9	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	1.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	1.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.6	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.1	3.1	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	0.8	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	4.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	2.2	GO:0038191	neuropilin binding(GO:0038191)
0.1	4.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	2.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	4.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248)
0.1	2.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	8.5	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	1.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	6.0	GO:0070888	E-box binding(GO:0070888)
0.1	6.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.6	GO:0005499	vitamin D binding(GO:0005499)
0.1	2.5	GO:0051787	misfolded protein binding(GO:0051787)
0.1	5.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	1.0	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	2.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.7	GO:0005124	scavenger receptor binding(GO:0005124)
0.1	4.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	1.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	2.3	GO:0043274	phospholipase binding(GO:0043274)
0.1	1.0	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	9.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	6.7	GO:0003823	antigen binding(GO:0003823)
0.1	0.8	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	1.1	GO:0005522	profilin binding(GO:0005522)
0.1	5.0	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	2.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.0	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1	6.2	GO:0001067	regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.1	0.6	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	1.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	2.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	1.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	0.4	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	1.2	GO:0005272	sodium channel activity(GO:0005272)
0.1	1.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	1.6	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	1.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	2.9	GO:0016831	carboxy-lyase activity(GO:0016831)
0.1	4.3	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.1	3.5	GO:0019213	deacetylase activity(GO:0019213)
0.1	2.8	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	2.8	GO:0051287	NAD binding(GO:0051287)
0.1	3.0	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	0.4	GO:0004966	galanin receptor activity(GO:0004966)
0.1	3.7	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.2	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.0	29.5	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0	2.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	6.3	GO:0005178	integrin binding(GO:0005178)
0.0	0.5	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	2.5	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	2.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	4.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	1.5	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.6	GO:0008432	JUN kinase binding(GO:0008432)
0.0	22.3	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.8	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	1.9	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0001729	ceramide kinase activity(GO:0001729)
0.0	2.6	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.2	GO:0015197	peptide transporter activity(GO:0015197)
0.0	7.2	GO:0045296	cadherin binding(GO:0045296)
0.0	1.2	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	17.5	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.0	0.1	GO:0004985	melanocortin receptor activity(GO:0004977) opioid receptor activity(GO:0004985)
0.0	1.3	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	2.7	GO:0005179	hormone activity(GO:0005179)
0.0	2.0	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	2.9	GO:0004175	endopeptidase activity(GO:0004175)
0.0	0.4	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	1.0	GO:0030276	clathrin binding(GO:0030276)
0.0	6.9	GO:0003779	actin binding(GO:0003779)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	22.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.6	24.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.4	3.8	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.4	8.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	13.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	5.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	6.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	4.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	3.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	9.5	PID AURORA A PATHWAY	Aurora A signaling
0.2	6.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	6.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	4.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	15.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	4.8	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	3.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.2	12.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	10.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	5.6	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	2.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	5.6	PID BMP PATHWAY	BMP receptor signaling
0.1	3.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	2.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	4.9	PID FOXO PATHWAY	FoxO family signaling
0.1	6.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	3.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	3.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	2.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	4.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	0.6	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	13.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	3.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	2.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.8	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	2.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.8	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	4.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	2.9	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.6	PID ENDOTHELIN PATHWAY	Endothelins
0.1	3.4	PID E2F PATHWAY	E2F transcription factor network
0.1	1.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	3.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	1.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	2.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	7.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	2.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	39.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	18.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.6	23.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.5	12.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5	7.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4	7.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.4	7.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4	8.9	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.4	4.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	5.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4	3.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.4	5.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	8.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.3	8.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.3	3.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	2.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	3.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	3.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.2	13.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.2	6.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	12.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	2.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	2.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.2	10.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.2	2.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	2.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	10.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	8.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	2.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	3.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	3.5	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	5.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	3.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	3.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	4.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	4.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	4.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	3.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	7.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	7.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	2.9	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	4.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	2.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	2.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.2	REACTOME OPSINS	Genes involved in Opsins
0.1	4.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	2.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	1.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	9.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	5.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.9	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	9.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	6.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	0.5	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	1.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	4.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	5.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	4.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	1.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	3.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	2.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	1.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation

Results for Ascl2

Z-value: 1.75

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Transcription factors associated with Ascl2

Activity-expression correlation:

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: