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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Atf4

Z-value: 0.99

Motif logo

Transcription factors associated with Atf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000042406.9 Atf4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf4mm39_v1_chr15_+_80139371_801393860.019.3e-01Click!

Activity profile of Atf4 motif

Sorted Z-values of Atf4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_119181703 7.79 ENSMUST00000028780.4
ChaC, cation transport regulator 1
chr8_+_86219191 5.91 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr15_+_9335636 5.16 ENSMUST00000072403.7
UDP glycosyltransferases 3 family, polypeptide A2
chr11_-_75313350 5.14 ENSMUST00000125982.2
ENSMUST00000137103.8
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75313412 4.78 ENSMUST00000138661.8
ENSMUST00000000769.14
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr19_-_43512929 4.28 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr7_+_44117511 3.75 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr10_-_127358231 3.48 ENSMUST00000219239.2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_+_44117444 3.47 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr10_-_127358300 3.42 ENSMUST00000026470.6
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_+_96162283 3.31 ENSMUST00000000010.9
ENSMUST00000174042.3
homeobox B9
chr7_+_44117475 3.28 ENSMUST00000118493.8
Josephin domain containing 2
chrX_+_102465616 3.05 ENSMUST00000182089.2
predicted gene, 26992
chr7_+_44117404 2.96 ENSMUST00000035844.11
Josephin domain containing 2
chr9_+_21746785 2.68 ENSMUST00000058777.8
angiopoietin-like 8
chr7_+_51528715 2.59 ENSMUST00000051912.13
growth arrest specific 2
chr9_+_32283779 2.57 ENSMUST00000047334.10
potassium inwardly-rectifying channel, subfamily J, member 1
chr11_+_67061908 2.52 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr13_-_53627110 2.50 ENSMUST00000021922.10
msh homeobox 2
chr10_-_83369247 2.44 ENSMUST00000146640.8
aldehyde dehydrogenase 1 family, member L2
chr8_+_95113066 2.41 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_+_67061837 2.40 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr11_-_120534469 2.31 ENSMUST00000141254.8
ENSMUST00000170556.8
ENSMUST00000151876.8
ENSMUST00000026133.15
ENSMUST00000139706.2
pyrroline-5-carboxylate reductase 1
chr14_-_32407203 2.23 ENSMUST00000096038.4
RIKEN cDNA 3425401B19 gene
chr1_-_180021039 2.09 ENSMUST00000160482.8
ENSMUST00000170472.8
coenzyme Q8A
chr7_+_51528788 1.97 ENSMUST00000107591.9
growth arrest specific 2
chr13_-_30729242 1.86 ENSMUST00000042834.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr4_+_129083553 1.74 ENSMUST00000106054.4
tyrosyl-tRNA synthetase
chr11_-_53321606 1.71 ENSMUST00000061326.5
ENSMUST00000109021.4
ubiquinol-cytochrome c reductase, complex III subunit VII
chr6_+_129510117 1.69 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr18_-_64649497 1.59 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr18_-_64649620 1.59 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr7_-_143153785 1.56 ENSMUST00000105909.4
ENSMUST00000010899.14
cysteinyl-tRNA synthetase
chr11_+_9141934 1.46 ENSMUST00000042740.13
ATP-binding cassette, sub-family A (ABC1), member 13
chr8_+_111760521 1.44 ENSMUST00000034441.8
alanyl-tRNA synthetase
chr9_-_44255456 1.42 ENSMUST00000077353.15
hydroxymethylbilane synthase
chr6_+_129510145 1.42 ENSMUST00000204487.3
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_+_55777807 1.37 ENSMUST00000226352.2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr1_+_185095232 1.36 ENSMUST00000046514.13
glutamyl-prolyl-tRNA synthetase
chr11_-_101062111 1.36 ENSMUST00000164474.8
ENSMUST00000043397.14
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_-_3551003 1.35 ENSMUST00000065703.9
ENSMUST00000203020.3
ENSMUST00000203821.3
T cell-interacting, activating receptor on myeloid cells 1
chr11_-_115167775 1.31 ENSMUST00000021078.3
ferredoxin reductase
chr3_-_89905927 1.29 ENSMUST00000197725.5
ENSMUST00000197767.5
ENSMUST00000197786.5
ENSMUST00000079724.9
HCLS1 associated X-1
chr15_+_99291100 1.29 ENSMUST00000159209.8
transmembrane BAX inhibitor motif containing 6
chr16_+_22737227 1.27 ENSMUST00000231880.2
fetuin beta
chr5_+_118307754 1.25 ENSMUST00000054836.7
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr13_+_49835576 1.24 ENSMUST00000165316.8
ENSMUST00000047363.14
isoleucine-tRNA synthetase
chr3_-_127202693 1.23 ENSMUST00000182078.9
ankyrin 2, brain
chr7_-_109092834 1.22 ENSMUST00000106739.8
tripartite motif-containing 66
chr1_-_71692320 1.19 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr3_-_127202663 1.12 ENSMUST00000182008.8
ENSMUST00000182547.8
ankyrin 2, brain
chr10_+_127126643 1.06 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr13_+_49835667 1.05 ENSMUST00000172254.3
isoleucine-tRNA synthetase
chr3_-_127202635 1.04 ENSMUST00000182959.8
ankyrin 2, brain
chr13_-_101829070 1.01 ENSMUST00000187009.7
phosphoinositide-3-kinase regulatory subunit 1
chr3_-_127202586 1.00 ENSMUST00000183095.3
ENSMUST00000182610.8
ankyrin 2, brain
chr15_+_99291491 0.99 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr6_+_129510331 0.96 ENSMUST00000204956.2
ENSMUST00000204639.2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr11_-_53321242 0.95 ENSMUST00000109019.8
ubiquinol-cytochrome c reductase, complex III subunit VII
chr16_-_23751144 0.95 ENSMUST00000231038.2
receptor transporter protein 2
chrX_+_163221035 0.91 ENSMUST00000033755.6
ankyrin repeat and SOCS box-containing 11
chr14_-_36857083 0.89 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr11_-_58425662 0.88 ENSMUST00000213188.3
olfactory receptor 330
chr14_-_50521663 0.88 ENSMUST00000213701.2
olfactory receptor 732
chr2_+_3514071 0.88 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr9_+_109760856 0.88 ENSMUST00000169851.8
microtubule-associated protein 4
chr5_-_90371816 0.86 ENSMUST00000118816.6
ENSMUST00000048363.10
cytochrome c oxidase assembly protein 18
chr5_-_148336574 0.84 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_20282684 0.82 ENSMUST00000004634.7
ENSMUST00000109594.8
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_156666485 0.82 ENSMUST00000111720.2
angiopoietin-like 1
chr12_+_108859557 0.81 ENSMUST00000221377.2
WD repeat domain 25
chr3_-_59038539 0.81 ENSMUST00000198838.2
purinergic receptor P2Y, G-protein coupled, 14
chr4_+_138606671 0.81 ENSMUST00000105804.2
phospholipase A2, group IIE
chr13_-_101829132 0.80 ENSMUST00000035532.13
phosphoinositide-3-kinase regulatory subunit 1
chr6_+_55014973 0.80 ENSMUST00000003572.10
glycyl-tRNA synthetase
chr15_+_98367777 0.79 ENSMUST00000216180.2
olfactory receptor 240, pseudogene 1
chr8_+_72795062 0.77 ENSMUST00000215324.2
olfactory receptor 372
chr7_+_79910948 0.76 ENSMUST00000117989.2
neugrin, neurite outgrowth associated
chr12_-_108859123 0.74 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr13_-_118523760 0.74 ENSMUST00000022245.10
mitochondrial ribosomal protein S30
chr3_-_89905547 0.73 ENSMUST00000199740.2
ENSMUST00000198782.2
HCLS1 associated X-1
chr5_-_145077048 0.68 ENSMUST00000031627.9
PDGFA associated protein 1
chr15_+_102012782 0.67 ENSMUST00000230474.2
tensin 2
chr14_-_56339915 0.67 ENSMUST00000015583.2
cathepsin G
chr7_+_109617456 0.67 ENSMUST00000084731.5
importin 7
chr19_-_50667079 0.66 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chr2_-_18053158 0.66 ENSMUST00000066885.6
SKI/DACH domain containing 1
chr10_+_100176698 0.63 ENSMUST00000168769.3
predicted gene 4302
chr6_+_65019793 0.63 ENSMUST00000204696.3
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_+_103980178 0.63 ENSMUST00000170919.2
predicted gene, 21293
chr10_+_104031258 0.63 ENSMUST00000163113.3
predicted gene 4340
chr10_+_104014239 0.63 ENSMUST00000179258.2
predicted gene, 21312
chr10_+_104022748 0.63 ENSMUST00000177792.2
predicted gene, 20765
chr15_+_99590098 0.62 ENSMUST00000228185.2
acid-sensing (proton-gated) ion channel 1
chr10_+_100181834 0.61 ENSMUST00000218922.2
predicted gene 4303
chr10_+_100186955 0.61 ENSMUST00000219159.2
predicted gene 4305
chr10_+_100197200 0.61 ENSMUST00000177945.2
predicted gene 4307
chr2_-_18053595 0.61 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr16_-_36154692 0.61 ENSMUST00000114850.3
cystatin domain containing 6
chr9_-_15023396 0.61 ENSMUST00000159985.2
hephaestin-like 1
chr5_+_42225303 0.60 ENSMUST00000087332.5
predicted gene 16223
chr15_+_99291455 0.60 ENSMUST00000162624.8
transmembrane BAX inhibitor motif containing 6
chr5_-_148336711 0.59 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_87811788 0.59 ENSMUST00000216461.2
ENSMUST00000217112.2
olfactory receptor 464
chr3_-_96170627 0.58 ENSMUST00000171473.3
H4 clustered histone 14
chr7_+_140043283 0.56 ENSMUST00000211093.3
ENSMUST00000216258.2
ENSMUST00000215308.2
ENSMUST00000217179.2
olfactory receptor 533
chr8_+_106427774 0.55 ENSMUST00000098444.9
ENSMUST00000212352.2
par-6 family cell polarity regulator alpha
chr19_-_40576817 0.54 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
aldehyde dehydrogenase 18 family, member A1
chr10_+_121575819 0.53 ENSMUST00000065600.8
ENSMUST00000136432.2
cDNA sequence BC048403
chr7_-_139956244 0.50 ENSMUST00000216727.2
olfactory receptor 530
chr4_+_117692583 0.44 ENSMUST00000169885.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_93241385 0.43 ENSMUST00000201421.4
ENSMUST00000202415.4
ENSMUST00000202217.3
septin 11
chr11_-_87716849 0.42 ENSMUST00000103177.10
lactoperoxidase
chr14_-_8068465 0.41 ENSMUST00000215479.2
olfactory receptor 721, pseudogene 1
chr19_-_40576897 0.41 ENSMUST00000025979.13
aldehyde dehydrogenase 18 family, member A1
chr7_-_103543692 0.40 ENSMUST00000081748.6
olfactory receptor 64
chr2_-_89423470 0.39 ENSMUST00000217254.2
ENSMUST00000217192.2
ENSMUST00000213221.2
olfactory receptor 1246
chr19_-_40576782 0.39 ENSMUST00000176939.8
aldehyde dehydrogenase 18 family, member A1
chrX_+_93278203 0.39 ENSMUST00000153900.8
kelch-like 15
chr11_+_100211363 0.39 ENSMUST00000152521.2
eukaryotic translation initiation factor 1
chr12_+_87762282 0.37 ENSMUST00000221442.2
eukaryotic translation initiation factor 1A domain containing 13
chr7_+_144450260 0.36 ENSMUST00000033389.7
ENSMUST00000207229.2
fibroblast growth factor 15
chr2_+_87853118 0.36 ENSMUST00000214438.2
olfactory receptor 1161
chr14_-_54655237 0.35 ENSMUST00000195999.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr16_+_36097505 0.35 ENSMUST00000042097.11
stefin A1
chr14_+_54422156 0.33 ENSMUST00000103707.2
T cell receptor alpha joining 34
chr18_+_40390013 0.33 ENSMUST00000096572.2
ENSMUST00000236889.2
potassium channel tetramerisation domain containing 16
chr4_-_118036827 0.32 ENSMUST00000097911.9
lysine (K)-specific demethylase 4A
chr1_-_78465479 0.32 ENSMUST00000190441.2
ENSMUST00000170217.8
ENSMUST00000188247.7
ENSMUST00000068333.14
phenylalanyl-tRNA synthetase, beta subunit
chr14_-_50538979 0.25 ENSMUST00000216195.2
ENSMUST00000214372.2
ENSMUST00000214756.2
olfactory receptor 733
chr10_-_68114543 0.25 ENSMUST00000219238.2
AT rich interactive domain 5B (MRF1-like)
chr19_-_8690330 0.24 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr6_-_97436223 0.24 ENSMUST00000113359.8
FERM domain containing 4B
chr7_-_140087224 0.22 ENSMUST00000209873.2
ENSMUST00000064392.8
ENSMUST00000215768.2
ENSMUST00000215340.2
olfactory receptor 536
chr1_-_31017049 0.18 ENSMUST00000178317.4
predicted gene 5698
chr11_+_57899890 0.16 ENSMUST00000071487.13
ENSMUST00000178636.2
La ribonucleoprotein domain family, member 1
chr3_-_59038160 0.16 ENSMUST00000197841.2
purinergic receptor P2Y, G-protein coupled, 14
chr5_+_93241287 0.13 ENSMUST00000074733.11
ENSMUST00000201700.4
ENSMUST00000202196.4
ENSMUST00000202308.4
septin 11
chr15_-_76191301 0.13 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr1_-_190915441 0.12 ENSMUST00000027941.14
activating transcription factor 3
chr12_+_85646162 0.10 ENSMUST00000050687.14
Jun dimerization protein 2
chr1_-_92412835 0.10 ENSMUST00000214928.3
olfactory receptor 1416
chr2_-_37007795 0.08 ENSMUST00000213817.2
ENSMUST00000215927.2
olfactory receptor 362
chr3_+_137849560 0.07 ENSMUST00000159622.8
tRNA methyltransferase 10A
chr12_+_73333553 0.04 ENSMUST00000140523.8
ENSMUST00000126488.8
solute carrier family 38, member 6
chr9_-_79700660 0.03 ENSMUST00000034878.12
transmembrane protein 30A
chr11_-_98291220 0.01 ENSMUST00000128897.2
post-GPI attachment to proteins 3
chr7_+_138448308 0.00 ENSMUST00000155672.8
protein phosphatase 2, regulatory subunit B, delta
chr4_-_41774097 0.00 ENSMUST00000108036.8
ENSMUST00000108037.9
ENSMUST00000108032.3
ENSMUST00000173865.9
ENSMUST00000155240.2
chemokine (C-C motif) ligand 27A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.5 5.9 GO:0042851 L-alanine metabolic process(GO:0042851)
1.4 4.3 GO:0006533 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.8 2.5 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.8 9.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.8 2.4 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.8 2.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.6 3.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 2.9 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.6 7.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 4.4 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 1.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 1.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.5 3.7 GO:0006561 proline biosynthetic process(GO:0006561)
0.4 2.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.4 2.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.4 1.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.4 2.7 GO:0021539 subthalamus development(GO:0021539)
0.3 2.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 0.8 GO:0015825 L-serine transport(GO:0015825)
0.3 4.9 GO:0001778 plasma membrane repair(GO:0001778)
0.3 1.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.3 4.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.4 GO:0006116 NADH oxidation(GO:0006116)
0.2 1.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.2 0.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.8 GO:0070127 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 5.2 GO:0080184 response to phenylpropanoid(GO:0080184)
0.1 0.4 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 3.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 4.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.8 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 2.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 13.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.4 GO:0015809 arginine transport(GO:0015809)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.9 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.4 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.8 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 1.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.4 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 4.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 3.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 3.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.9 GO:0070552 BRISC complex(GO:0070552)
0.6 4.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.6 2.4 GO:1990037 Lewy body core(GO:1990037)
0.6 9.9 GO:0043203 axon hillock(GO:0043203)
0.5 1.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 4.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.4 1.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 4.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 4.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 4.4 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0010369 chromocenter(GO:0010369)
0.0 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.9 GO:0043679 axon terminus(GO:0043679)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
1.4 4.3 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 7.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.2 5.9 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.8 2.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.8 3.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.8 2.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.6 4.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 2.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.5 1.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.5 1.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.5 2.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 1.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.4 1.3 GO:0019202 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.3 2.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.8 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 4.1 GO:0030957 Tat protein binding(GO:0030957)
0.2 0.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 2.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 5.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 5.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 13.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.2 GO:0045340 mercury ion binding(GO:0045340)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 9.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.3 GO:0070402 NADPH binding(GO:0070402)
0.0 4.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 4.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 9.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 3.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 4.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)