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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Atf5

Z-value: 0.98

Motif logo

Transcription factors associated with Atf5

Gene Symbol Gene ID Gene Info
ENSMUSG00000038539.16 Atf5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf5mm39_v1_chr7_-_44465998_44466082-0.133.0e-01Click!

Activity profile of Atf5 motif

Sorted Z-values of Atf5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_55173696 11.26 ENSMUST00000037814.8
CKLF-like MARVEL transmembrane domain containing 5
chr7_-_84021655 10.64 ENSMUST00000208392.2
ENSMUST00000208232.2
ENSMUST00000208863.2
aryl hydrocarbon receptor nuclear translocator 2
chr7_+_51271742 10.57 ENSMUST00000032710.7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chrX_+_165127688 9.61 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
glycoprotein m6b
chr14_+_55173936 8.87 ENSMUST00000227441.2
CKLF-like MARVEL transmembrane domain containing 5
chr4_-_91264670 8.67 ENSMUST00000107109.9
ENSMUST00000107111.9
ENSMUST00000107120.8
ELAV like RNA binding protein 1
chr6_-_127746390 8.67 ENSMUST00000032500.9
protein arginine N-methyltransferase 8
chrX_+_40490005 8.64 ENSMUST00000115103.9
ENSMUST00000076349.12
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_79048674 8.41 ENSMUST00000230261.2
ENSMUST00000040019.5
SRY (sex determining region Y)-box 10
chr8_+_55407872 8.16 ENSMUST00000033915.9
glycoprotein m6a
chr14_+_71127882 7.21 ENSMUST00000227697.2
glial cell line derived neurotrophic factor family receptor alpha 2
chr1_-_135095344 6.79 ENSMUST00000027682.9
G protein-coupled receptor 37-like 1
chr12_+_89779237 6.48 ENSMUST00000110133.9
ENSMUST00000110130.4
neurexin III
chrX_+_40490353 6.16 ENSMUST00000165288.2
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_78090591 5.89 ENSMUST00000120592.2
parvalbumin
chr3_+_7431717 5.88 ENSMUST00000192468.2
ENSMUST00000028999.12
protein kinase inhibitor, alpha
chr14_-_124914516 5.61 ENSMUST00000095529.10
fibroblast growth factor 14
chr1_+_32211792 5.51 ENSMUST00000027226.12
ENSMUST00000189878.2
ENSMUST00000188257.7
ENSMUST00000185666.2
KH domain containing, RNA binding, signal transduction associated 2
chr1_-_22845124 5.35 ENSMUST00000115273.10
regulating synaptic membrane exocytosis 1
chr1_-_158183894 5.31 ENSMUST00000004133.11
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr11_+_87469211 5.17 ENSMUST00000107962.8
ENSMUST00000122067.8
septin 4
chr2_+_177783713 5.17 ENSMUST00000103066.10
phosphatase and actin regulator 3
chr15_-_63932176 5.16 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
CYFIP related Rac1 interactor B
chr9_-_57513510 5.14 ENSMUST00000215487.2
ENSMUST00000045068.10
complexin 3
chr15_-_63932288 4.90 ENSMUST00000063838.11
ENSMUST00000228908.2
CYFIP related Rac1 interactor B
chr12_+_89779178 4.73 ENSMUST00000238943.2
neurexin III
chr18_-_23174698 4.58 ENSMUST00000097651.10
nucleolar protein 4
chr17_+_72076678 4.57 ENSMUST00000230427.2
ENSMUST00000229952.2
ENSMUST00000230333.2
CAP-GLY domain containing linker protein family, member 4
chr16_-_10265204 4.57 ENSMUST00000051118.7
trans-golgi network vesicle protein 23A
chr1_+_153541412 4.56 ENSMUST00000111814.8
ENSMUST00000111810.2
regulator of G-protein signaling 8
chr3_-_79645101 4.37 ENSMUST00000078527.13
relaxin/insulin-like family peptide receptor 1
chr4_+_102427247 4.28 ENSMUST00000097950.9
phosphodiesterase 4B, cAMP specific
chr18_+_66005891 4.11 ENSMUST00000173985.10
gastrin releasing peptide
chr19_-_46315543 4.10 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
pleckstrin and Sec7 domain containing
chr2_+_30331839 4.10 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr17_+_72076728 3.94 ENSMUST00000230305.2
CAP-GLY domain containing linker protein family, member 4
chr3_-_94343874 3.82 ENSMUST00000204913.3
ENSMUST00000191506.8
ENSMUST00000199678.4
ornithine decarboxylase antizyme 3
chr8_+_106075475 3.78 ENSMUST00000073149.7
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr9_-_37344542 3.78 ENSMUST00000115038.3
roundabout guidance receptor 3
chr15_+_22549108 3.74 ENSMUST00000163361.8
cadherin 18
chr12_+_3415107 3.73 ENSMUST00000220210.2
kinesin family member 3C
chr14_+_71127540 3.69 ENSMUST00000022699.10
glial cell line derived neurotrophic factor family receptor alpha 2
chr10_-_109669053 3.61 ENSMUST00000238286.2
neuron navigator 3
chr17_+_17669082 3.48 ENSMUST00000140134.2
limb and CNS expressed 1
chr14_-_4198510 3.36 ENSMUST00000133460.2
ENSMUST00000132374.9
NFKB inhibitor interacting Ras-like protein 1
chr8_-_29709455 3.22 ENSMUST00000211448.2
ENSMUST00000210298.2
ENSMUST00000209401.2
ENSMUST00000210785.2
unc-5 netrin receptor D
chr15_+_41694317 3.19 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr8_-_29709652 3.13 ENSMUST00000168630.4
unc-5 netrin receptor D
chr6_-_40562700 2.93 ENSMUST00000177178.2
ENSMUST00000129948.9
ENSMUST00000101491.11
C-type lectin domain family 5, member a
chr3_+_113824181 2.93 ENSMUST00000123619.8
ENSMUST00000092155.12
collagen, type XI, alpha 1
chrX_-_166907286 2.86 ENSMUST00000239138.2
FERM and PDZ domain containing 4
chr1_-_157084252 2.83 ENSMUST00000134543.8
RAS protein activator like 2
chr15_-_12493574 2.80 ENSMUST00000186113.2
PDZ domain containing 2
chr9_+_32027335 2.78 ENSMUST00000174641.8
Rho GTPase activating protein 32
chr18_+_35695199 2.70 ENSMUST00000236860.2
ENSMUST00000166793.10
ENSMUST00000237780.2
ENSMUST00000236507.2
ENSMUST00000235960.2
ENSMUST00000237061.2
matrin 3
chr19_-_46314945 2.65 ENSMUST00000225781.2
ENSMUST00000223903.2
pleckstrin and Sec7 domain containing
chr1_+_153541339 2.59 ENSMUST00000147700.8
ENSMUST00000147482.8
regulator of G-protein signaling 8
chr19_-_11848669 2.58 ENSMUST00000087857.3
olfactory receptor 1419
chr7_+_127661835 2.46 ENSMUST00000106242.10
ENSMUST00000120355.8
ENSMUST00000106240.9
ENSMUST00000098015.10
integrin alpha M
predicted gene, 49368
chr18_+_35695736 2.42 ENSMUST00000235851.2
ENSMUST00000235581.2
matrin 3
chr12_+_3415143 2.41 ENSMUST00000020999.7
kinesin family member 3C
chr18_+_35695339 2.39 ENSMUST00000237365.2
matrin 3
chr18_+_35695485 2.31 ENSMUST00000235199.2
ENSMUST00000237744.2
ENSMUST00000236276.2
matrin 3
chr7_-_85985625 2.28 ENSMUST00000069279.5
olfactory receptor 307
chr19_-_18978463 2.12 ENSMUST00000040153.15
ENSMUST00000112828.8
RAR-related orphan receptor beta
chr11_-_95733235 2.06 ENSMUST00000059026.10
ABI family member 3
chr7_+_127661807 2.05 ENSMUST00000064821.14
integrin alpha M
chr5_+_20112500 1.98 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_77129786 1.92 ENSMUST00000228558.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_+_122712809 1.91 ENSMUST00000075888.6
zinc finger protein of the cerebellum 2
chr2_+_172235702 1.85 ENSMUST00000099061.9
ENSMUST00000103073.9
Cas scaffolding protein family member 4
chr4_-_127864744 1.84 ENSMUST00000030614.3
cDNA sequence CK137956
chr19_+_45352173 1.76 ENSMUST00000223764.2
ENSMUST00000065601.13
ENSMUST00000224102.2
ENSMUST00000111936.4
beta-transducin repeat containing protein
chr4_+_21727727 1.75 ENSMUST00000108240.3
cyclin C
chr5_+_20112704 1.68 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_-_20600442 1.67 ENSMUST00000170265.8
phosphodiesterase 7B
chr11_-_61652866 1.67 ENSMUST00000004955.14
ENSMUST00000168115.8
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr6_+_33226020 1.66 ENSMUST00000052266.15
ENSMUST00000090381.11
ENSMUST00000115080.2
exocyst complex component 4
chr16_-_45830575 1.66 ENSMUST00000130481.2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_-_153726930 1.65 ENSMUST00000059607.8
transmembrane epididymal family member 2
chr11_+_70104929 1.65 ENSMUST00000094055.10
ENSMUST00000126296.8
ENSMUST00000136328.2
ENSMUST00000153993.3
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr15_-_77129706 1.60 ENSMUST00000228361.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_-_77037972 1.52 ENSMUST00000111581.4
ENSMUST00000166610.8
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_59555423 1.48 ENSMUST00000114243.8
predicted gene 973
chr19_-_7460550 1.46 ENSMUST00000088169.7
reticulon 3
chr2_+_172235820 1.44 ENSMUST00000109136.3
ENSMUST00000228775.2
Cas scaffolding protein family member 4
chr12_-_64521464 1.44 ENSMUST00000059833.8
fibrous sheath CABYR binding protein
chr11_+_83193495 1.39 ENSMUST00000176430.8
ENSMUST00000065692.14
ENSMUST00000142680.2
adaptor-related protein complex 2, beta 1 subunit
chr2_-_120370333 1.38 ENSMUST00000171215.8
zinc finger protein 106
chr18_+_69633741 1.36 ENSMUST00000207214.2
ENSMUST00000201094.4
ENSMUST00000200703.4
ENSMUST00000202765.4
transcription factor 4
chr16_+_37909363 1.33 ENSMUST00000023507.13
glycogen synthase kinase 3 beta
chr5_-_114127800 1.33 ENSMUST00000077689.14
slingshot protein phosphatase 1
chr18_+_65714774 1.32 ENSMUST00000182979.8
zinc finger protein 532
chr12_+_4684620 1.31 ENSMUST00000217672.2
intersectin 2
chr10_-_20600797 1.31 ENSMUST00000020165.14
phosphodiesterase 7B
chr18_+_65715156 1.25 ENSMUST00000237553.2
ENSMUST00000237712.2
ENSMUST00000182684.8
zinc finger protein 532
chr13_+_24925192 1.22 ENSMUST00000136906.2
armadillo-like helical domain containing 2
chr15_-_77037756 1.22 ENSMUST00000227314.2
ENSMUST00000227930.2
ENSMUST00000227533.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_+_45352514 1.22 ENSMUST00000224318.2
ENSMUST00000223684.2
beta-transducin repeat containing protein
chr19_-_7460600 1.18 ENSMUST00000235593.2
ENSMUST00000088171.12
ENSMUST00000065304.13
ENSMUST00000025667.14
reticulon 3
chr6_+_149310471 1.15 ENSMUST00000086829.11
ENSMUST00000111513.9
BICD cargo adaptor 1
chr9_+_106377181 1.14 ENSMUST00000085114.8
IQ motif containing F1
chr7_+_28834350 1.11 ENSMUST00000159975.8
ENSMUST00000094617.11
ENSMUST00000032811.12
RAS guanyl releasing protein 4
chr17_+_20639425 1.08 ENSMUST00000170076.2
vomeronasal 1 receptor 224
chr18_+_62086122 1.02 ENSMUST00000051720.6
ENSMUST00000235860.2
SH3 domain and tetratricopeptide repeats 2
chr18_+_65715351 1.00 ENSMUST00000235669.2
ENSMUST00000183319.8
ENSMUST00000236523.2
ENSMUST00000237886.2
zinc finger protein 532
chr5_-_100946434 1.00 ENSMUST00000044684.14
helicase, POLQ-like
chr2_-_32665342 0.90 ENSMUST00000161089.8
ENSMUST00000066478.9
ENSMUST00000161950.8
ENSMUST00000091059.12
tetratricopeptide repeat domain 16
chr18_+_65715460 0.85 ENSMUST00000169679.8
ENSMUST00000183326.2
zinc finger protein 532
chr13_-_21257469 0.82 ENSMUST00000058168.2
olfactory receptor 1370
chr5_-_100946334 0.80 ENSMUST00000133845.8
helicase, POLQ-like
chr11_-_46057224 0.75 ENSMUST00000020679.3
NIPA-like domain containing 4
chrX_-_36373910 0.74 ENSMUST00000076265.13
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr2_+_174257597 0.74 ENSMUST00000109075.8
ENSMUST00000016397.7
negative elongation factor complex member C/D, Th1l
chr14_+_20724378 0.70 ENSMUST00000224492.2
ENSMUST00000223751.2
ENSMUST00000225108.2
ENSMUST00000224754.2
Sec24 related gene family, member C (S. cerevisiae)
chr6_+_116528102 0.61 ENSMUST00000122096.3
eukaryotic translation initiation factor 4A3 like 2
chr16_+_84312009 0.60 ENSMUST00000209558.2
RIKEN cDNA A730009L09 gene
chr19_-_37155410 0.59 ENSMUST00000133988.2
cytoplasmic polyadenylation element binding protein 3
chr2_+_111158766 0.58 ENSMUST00000090326.2
olfactory receptor 1281
chr4_-_154181562 0.55 ENSMUST00000105643.8
ENSMUST00000133533.8
ENSMUST00000097762.11
transformation related protein 73
chr4_+_21727695 0.51 ENSMUST00000065928.11
ENSMUST00000102997.8
ENSMUST00000120679.8
cyclin C
chr8_+_82499732 0.50 ENSMUST00000170160.8
inositol polyphosphate-4-phosphatase, type II
chr3_+_99161070 0.49 ENSMUST00000029462.10
T-box 15
chrX_-_17438520 0.48 ENSMUST00000026016.13
FUN14 domain containing 1
chr17_+_85272459 0.48 ENSMUST00000234540.2
protein phosphatase 1B, magnesium dependent, beta isoform
chr11_+_4852212 0.45 ENSMUST00000142543.3
THO complex 5
chr5_-_115479203 0.45 ENSMUST00000139167.3
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr17_+_56259617 0.42 ENSMUST00000003274.8
Epstein-Barr virus induced gene 3
chrX_-_17437801 0.40 ENSMUST00000177213.8
FUN14 domain containing 1
chr18_-_15197138 0.37 ENSMUST00000234864.2
potassium channel tetramerisation domain containing 1
chr4_-_119272690 0.37 ENSMUST00000238287.2
ENSMUST00000238759.2
ENSMUST00000063642.10
coiled-coil domain containing 30
chr3_+_89987749 0.31 ENSMUST00000127955.2
tropomyosin 3, gamma
chr16_+_17716480 0.31 ENSMUST00000055374.8
testis-specific serine kinase 2
chr1_-_65112680 0.27 ENSMUST00000114064.3
crystallin, gamma C
chr10_+_89906956 0.23 ENSMUST00000183109.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_49004584 0.16 ENSMUST00000203007.2
olfactory receptor 1396
chr1_-_171885140 0.14 ENSMUST00000059794.4
nescient helix loop helix 1
chr2_+_89821565 0.14 ENSMUST00000111509.3
ENSMUST00000213909.3
olfactory receptor 1261
chr7_-_37470184 0.10 ENSMUST00000176680.8
zinc finger protein 536
chr17_+_35439810 0.09 ENSMUST00000118793.2
predicted gene 16181
chr18_-_15196612 0.08 ENSMUST00000168989.9
potassium channel tetramerisation domain containing 1
chr15_-_99864936 0.07 ENSMUST00000100209.6
family with sequence similarity 186, member A
chr11_-_96714813 0.04 ENSMUST00000142065.2
ENSMUST00000167110.8
nuclear factor, erythroid derived 2,-like 1
chr4_+_118516149 0.02 ENSMUST00000213189.3
olfactory receptor 62

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.7 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.5 4.4 GO:0060618 nipple development(GO:0060618)
1.4 4.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
1.2 9.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
1.2 10.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.1 5.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
1.1 8.4 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
1.0 3.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.9 5.3 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.8 3.8 GO:0061643 chemoattraction of axon(GO:0061642) chemorepulsion of axon(GO:0061643)
0.7 5.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.6 4.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.5 2.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.5 1.9 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.5 7.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.5 6.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 1.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.4 1.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.4 10.9 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.4 2.9 GO:0035989 tendon development(GO:0035989)
0.4 6.8 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.4 11.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 4.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 2.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.3 3.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 12.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 2.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 5.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 14.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 6.4 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.2 2.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 1.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.6 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 1.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 1.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.2 6.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 3.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 8.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.4 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 2.1 GO:0046549 retinal cone cell development(GO:0046549)
0.1 9.8 GO:0003170 heart valve development(GO:0003170)
0.1 0.5 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 2.9 GO:0002076 osteoblast development(GO:0002076)
0.1 3.5 GO:0097352 autophagosome maturation(GO:0097352)
0.1 5.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 3.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.4 GO:2000002 negative regulation of macrophage differentiation(GO:0045650) negative regulation of DNA damage checkpoint(GO:2000002)
0.1 6.1 GO:0072384 organelle transport along microtubule(GO:0072384)
0.1 5.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 10.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 5.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 8.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 2.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.8 14.8 GO:0043083 synaptic cleft(GO:0043083)
0.6 8.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 6.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.4 1.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.4 10.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.2 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.2 2.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.7 GO:0032021 NELF complex(GO:0032021)
0.2 2.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 4.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 7.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 8.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.5 GO:0070722 Tle3-Aes complex(GO:0070722)
0.1 4.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877) Wnt signalosome(GO:1990909)
0.1 11.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.8 GO:1904949 ATPase complex(GO:1904949)
0.1 6.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.5 GO:0008305 integrin complex(GO:0008305)
0.1 9.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 5.9 GO:0043195 terminal bouton(GO:0043195)
0.0 10.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.9 GO:0043197 dendritic spine(GO:0043197)
0.0 5.6 GO:0098794 postsynapse(GO:0098794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.8 14.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.4 8.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
1.0 4.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.0 3.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.8 10.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.6 4.5 GO:0001851 complement component C3b binding(GO:0001851)
0.6 1.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.4 10.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.4 2.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 1.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.4 3.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 2.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.8 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.3 7.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 5.5 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.4 GO:0001515 opioid peptide activity(GO:0001515)
0.2 7.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 9.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 6.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 5.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 4.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 6.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 5.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 7.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 5.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 6.1 GO:0019894 kinesin binding(GO:0019894)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 14.2 GO:0005125 cytokine activity(GO:0005125)
0.1 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 8.0 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.4 GO:0042562 hormone binding(GO:0042562)
0.0 6.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.0 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 5.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 6.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.8 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 5.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 5.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 6.1 REACTOME KINESINS Genes involved in Kinesins
0.2 10.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 10.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 6.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 4.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 4.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 7.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing