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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Bbx

Z-value: 0.46

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Transcription factors associated with Bbx

Gene Symbol Gene ID Gene Info
Bbx
ENSMUSG00000022641.16 Bbx

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bbxmm39_v1_chr16_-_50252703_502527720.262.6e-02Click!

Activity profile of Bbx motif

Sorted Z-values of Bbx motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Bbx

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_46655324 3.76 ENSMUST00000021802.16
Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr12_+_103354915 3.30 ENSMUST00000101094.9
ENSMUST00000021620.13
Otub2
OTU domain, ubiquitin aldehyde binding 2
chr16_+_20511991 3.24 ENSMUST00000149543.9
ENSMUST00000232207.2
ENSMUST00000118919.9
Fam131a
family with sequence similarity 131, member A
chr13_-_52685305 3.01 ENSMUST00000057442.8
Diras2
DIRAS family, GTP-binding RAS-like 2
chr11_-_79418500 2.46 ENSMUST00000154415.2
Evi2a
ecotropic viral integration site 2a
chr13_+_49761506 2.40 ENSMUST00000021822.7
Ogn
osteoglycin
chrX_-_149597261 2.38 ENSMUST00000026302.13
ENSMUST00000129768.8
ENSMUST00000112699.9
Maged2
MAGE family member D2
chr15_+_91949032 2.17 ENSMUST00000169825.8
Cntn1
contactin 1
chr18_+_37554471 1.69 ENSMUST00000053073.6
Pcdhb11
protocadherin beta 11
chr1_-_144651157 1.62 ENSMUST00000027603.4
Rgs18
regulator of G-protein signaling 18
chr17_+_41121979 1.34 ENSMUST00000024721.8
ENSMUST00000233740.2
Rhag
Rhesus blood group-associated A glycoprotein
chr10_-_44334683 1.32 ENSMUST00000105490.3
Prdm1
PR domain containing 1, with ZNF domain
chr8_+_46111703 1.26 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
Sorbs2
sorbin and SH3 domain containing 2
chr11_+_59197746 1.24 ENSMUST00000000128.10
ENSMUST00000108783.4
Wnt9a
wingless-type MMTV integration site family, member 9A
chr15_+_21111428 1.16 ENSMUST00000075132.8
Cdh12
cadherin 12
chr12_-_86125793 1.08 ENSMUST00000003687.8
Tgfb3
transforming growth factor, beta 3
chr15_+_30457772 0.97 ENSMUST00000228282.2
Ctnnd2
catenin (cadherin associated protein), delta 2
chr15_-_11907267 0.96 ENSMUST00000228489.2
Npr3
natriuretic peptide receptor 3
chr10_-_44334711 0.92 ENSMUST00000039174.11
Prdm1
PR domain containing 1, with ZNF domain
chr2_-_134396268 0.91 ENSMUST00000028704.3
Hao1
hydroxyacid oxidase 1, liver
chr10_+_58207229 0.85 ENSMUST00000238939.2
Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_85857726 0.76 ENSMUST00000130320.8
Fbxo7
F-box protein 7
chr13_-_98152768 0.69 ENSMUST00000238746.2
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr8_+_46111778 0.67 ENSMUST00000143820.8
Sorbs2
sorbin and SH3 domain containing 2
chr15_-_80929669 0.66 ENSMUST00000135047.2
Mrtfa
myocardin related transcription factor A
chrX_+_158491589 0.63 ENSMUST00000080394.13
Sh3kbp1
SH3-domain kinase binding protein 1
chr18_-_60724855 0.61 ENSMUST00000056533.9
Myoz3
myozenin 3
chr2_-_90301592 0.54 ENSMUST00000111493.8
Ptprj
protein tyrosine phosphatase, receptor type, J
chr9_-_106448182 0.52 ENSMUST00000085111.5
Iqcf4
IQ motif containing F4
chr8_+_71069476 0.50 ENSMUST00000052437.6
Lrrc25
leucine rich repeat containing 25
chr8_+_46111310 0.50 ENSMUST00000153798.8
Sorbs2
sorbin and SH3 domain containing 2
chrX_+_77413242 0.46 ENSMUST00000035626.8
4930480E11Rik
RIKEN cDNA 4930480E11 gene
chr6_+_67890534 0.44 ENSMUST00000197406.5
ENSMUST00000103311.3
Igkv11-125
immunoglobulin kappa variable 11-125
chr7_-_97970388 0.44 ENSMUST00000120520.8
Acer3
alkaline ceramidase 3
chr2_+_122146153 0.40 ENSMUST00000099461.4
Duox1
dual oxidase 1
chr1_-_163552693 0.39 ENSMUST00000159679.8
Mettl11b
methyltransferase like 11B
chr10_+_85858050 0.34 ENSMUST00000120344.8
ENSMUST00000117597.2
Fbxo7
F-box protein 7
chr1_-_144427302 0.32 ENSMUST00000184189.3
Rgs21
regulator of G-protein signalling 21
chr10_+_129334361 0.29 ENSMUST00000203966.3
Olfr790
olfactory receptor 790
chr2_+_136734088 0.27 ENSMUST00000099311.9
Slx4ip
SLX4 interacting protein
chrX_+_67805443 0.25 ENSMUST00000069731.12
ENSMUST00000114647.8
Fmr1nb
Fmr1 neighbor
chr13_-_65200204 0.23 ENSMUST00000222769.2
Prss47
protease, serine 47
chr12_-_25147139 0.13 ENSMUST00000221761.2
Id2
inhibitor of DNA binding 2
chr2_+_87185159 0.12 ENSMUST00000215163.3
Olfr1120
olfactory receptor 1120
chr11_-_87788066 0.07 ENSMUST00000217095.2
ENSMUST00000215150.2
Olfr463
olfactory receptor 463
chr10_-_107321938 0.05 ENSMUST00000000445.2
Myf5
myogenic factor 5
chr1_-_155908695 0.05 ENSMUST00000136397.8
Tor1aip1
torsin A interacting protein 1
chr9_-_38585897 0.01 ENSMUST00000215461.3
Olfr918
olfactory receptor 918

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.4 1.1 GO:0003032 detection of oxygen(GO:0003032)
0.3 1.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 2.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 3.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 1.1 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 1.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 1.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 3.8 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 2.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.0 2.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 1.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990037 Lewy body core(GO:1990037)
0.0 3.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 0.9 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 1.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 3.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 1.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 2.4 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.2 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation