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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Brca1

Z-value: 1.09

Motif logo

Transcription factors associated with Brca1

Gene Symbol Gene ID Gene Info
ENSMUSG00000017146.13 Brca1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Brca1mm39_v1_chr11_-_101442663_101442719-0.235.1e-02Click!

Activity profile of Brca1 motif

Sorted Z-values of Brca1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Brca1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_107107558 11.44 ENSMUST00000105280.5
lin-7 homolog A (C. elegans)
chr16_+_20514925 7.75 ENSMUST00000128273.2
family with sequence similarity 131, member A
chr2_-_73605387 7.15 ENSMUST00000166199.9
chimerin 1
chr13_+_42834989 5.83 ENSMUST00000149235.8
phosphatase and actin regulator 1
chrX_+_165127688 5.72 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
glycoprotein m6b
chr3_-_121076745 5.07 ENSMUST00000135818.8
ENSMUST00000137234.2
TLC domain containing 4
chr13_+_68745542 5.02 ENSMUST00000222604.2
RIKEN cDNA 1700001L19 gene
chr10_+_107107477 4.83 ENSMUST00000020057.16
lin-7 homolog A (C. elegans)
chr13_+_68745528 4.73 ENSMUST00000022007.8
RIKEN cDNA 1700001L19 gene
chr2_-_57942844 4.69 ENSMUST00000090940.6
ermin, ERM-like protein
chr15_-_96917804 4.35 ENSMUST00000231039.2
solute carrier family 38, member 4
chrX_+_134894573 4.27 ENSMUST00000058119.9
adipocyte-related X-chromosome expressed sequence 2
chr15_-_96918203 4.14 ENSMUST00000166223.2
solute carrier family 38, member 4
chr5_+_16139683 4.12 ENSMUST00000167946.9
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr9_+_89791943 4.00 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1
chr4_+_98919183 4.00 ENSMUST00000030280.7
angiopoietin-like 3
chr6_-_122778598 3.91 ENSMUST00000165884.8
solute carrier family 2 (facilitated glucose transporter), member 3
chrX_+_149377416 3.76 ENSMUST00000112713.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_101749140 3.57 ENSMUST00000106934.2
ADP-ribosyltransferase 5
chr11_+_104441489 3.51 ENSMUST00000018800.9
myosin, light polypeptide 4
chr4_-_138123700 3.43 ENSMUST00000105032.4
family with sequence similarity 43, member B
chr4_-_11966367 3.38 ENSMUST00000056050.5
ENSMUST00000108299.2
ENSMUST00000108297.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_-_100486950 3.37 ENSMUST00000223020.2
ENSMUST00000062957.8
tetratricopeptide repeat domain 7B
chr13_+_93441447 3.28 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
homer scaffolding protein 1
chr16_+_41353212 3.24 ENSMUST00000078873.11
limbic system-associated membrane protein
chr5_+_35214110 3.21 ENSMUST00000101298.9
ENSMUST00000114270.8
ENSMUST00000133381.2
docking protein 7
chr5_+_20112500 3.17 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_41891111 3.13 ENSMUST00000109290.2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr7_-_101749433 3.12 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr2_-_45000389 3.07 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
zinc finger E-box binding homeobox 2
chr13_+_4486105 3.06 ENSMUST00000156277.2
aldo-keto reductase family 1, member C6
chr18_+_37085673 3.05 ENSMUST00000192512.6
ENSMUST00000192295.2
ENSMUST00000115661.5
protocadherin alpha 4
predicted gene, 42416
chr3_-_107838895 3.04 ENSMUST00000133947.9
ENSMUST00000124215.2
ENSMUST00000106688.8
ENSMUST00000106687.9
glutathione S-transferase, mu 7
chr11_-_41891359 2.98 ENSMUST00000070735.10
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr17_-_90395568 2.94 ENSMUST00000173222.2
neurexin I
chr1_-_46893206 2.92 ENSMUST00000027131.6
solute carrier family 39 (zinc transporter), member 10
chr6_-_122317457 2.92 ENSMUST00000160843.8
polyhomeotic 1
chr14_-_78970160 2.84 ENSMUST00000226342.3
diacylglycerol kinase, eta
chr19_+_4771089 2.81 ENSMUST00000238976.3
spectrin beta, non-erythrocytic 2
chr13_-_95386776 2.80 ENSMUST00000162153.9
ENSMUST00000160957.9
ENSMUST00000159598.2
ENSMUST00000162412.8
phosphodiesterase 8B
chr9_+_43996236 2.77 ENSMUST00000065461.9
ENSMUST00000176416.8
ubiquitin specific peptidase 2
chr17_+_71511642 2.70 ENSMUST00000126681.8
lipin 2
chr1_-_132635078 2.66 ENSMUST00000187861.7
neurofascin
chr1_-_132635042 2.66 ENSMUST00000043189.14
neurofascin
chr5_-_87240405 2.66 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr1_+_37068387 2.65 ENSMUST00000067178.14
ENSMUST00000238500.2
von Willebrand factor A domain containing 3B
chr10_-_33500583 2.63 ENSMUST00000161692.2
ENSMUST00000160299.2
ENSMUST00000019920.13
clavesin 2
chr6_-_142418801 2.62 ENSMUST00000032371.8
glycogen synthase 2
chr7_-_112968533 2.61 ENSMUST00000047091.14
ENSMUST00000119278.8
BTB (POZ) domain containing 10
chr7_+_51528715 2.59 ENSMUST00000051912.13
growth arrest specific 2
chr9_+_110948492 2.54 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr2_-_113659360 2.54 ENSMUST00000024005.8
secretogranin V
chr2_+_25178147 2.53 ENSMUST00000028340.4
transmembrane protein 210
chr10_+_86599836 2.48 ENSMUST00000218802.2
predicted gene, 49358
chr6_-_122317484 2.48 ENSMUST00000112600.9
polyhomeotic 1
chr2_+_67935015 2.46 ENSMUST00000042456.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_-_133830613 2.42 ENSMUST00000203168.2
ENSMUST00000048032.5
kidney androgen regulated protein
chr8_+_12965876 2.38 ENSMUST00000110876.9
ENSMUST00000110879.9
mcf.2 transforming sequence-like
chr7_-_27252543 2.37 ENSMUST00000127240.8
ENSMUST00000117095.8
ENSMUST00000117611.8
phospholipase D family, member 3
chr5_+_67126304 2.34 ENSMUST00000132991.5
LIM and calponin homology domains 1
chr8_+_55024446 2.33 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr14_-_20706556 2.32 ENSMUST00000090469.8
myozenin 1
chr10_+_40446326 2.26 ENSMUST00000078314.14
solute carrier family 22 (organic cation transporter), member 16
chr2_-_104324035 2.23 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr16_+_34471558 2.21 ENSMUST00000023530.5
ropporin, rhophilin associated protein 1
chr7_+_27252658 2.21 ENSMUST00000067386.14
ENSMUST00000191126.7
ENSMUST00000187960.7
RIKEN cDNA 2310022A10 gene
chr1_+_93271340 2.20 ENSMUST00000185498.7
protein phosphatase 1, regulatory subunit 7
chr4_+_148085179 2.18 ENSMUST00000103230.5
natriuretic peptide type A
chr2_+_109523908 2.17 ENSMUST00000111045.9
brain derived neurotrophic factor
chr10_+_40446605 2.15 ENSMUST00000019978.9
solute carrier family 22 (organic cation transporter), member 16
chr2_-_120681078 2.10 ENSMUST00000028740.11
tau tubulin kinase 2
chr3_+_20011405 2.04 ENSMUST00000108325.9
ceruloplasmin
chrX_+_111150171 1.99 ENSMUST00000164272.3
ENSMUST00000132037.2
RIKEN cDNA 4933403O08 gene
chr12_+_113507528 1.96 ENSMUST00000053086.3
a disintegrin and metallopeptidase domain 6A
chr9_-_108911438 1.93 ENSMUST00000192801.2
translational machinery associated 7
chr6_+_17693941 1.91 ENSMUST00000115420.8
ENSMUST00000115419.8
suppression of tumorigenicity 7
chr17_+_43671314 1.85 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr14_+_32555912 1.81 ENSMUST00000104926.3
family with sequence similarity 170, member B
chr5_+_77151902 1.78 ENSMUST00000071199.9
ADP-ribosylation factor-like 9
chr6_-_40917431 1.75 ENSMUST00000122181.8
ENSMUST00000031935.10
RIKEN cDNA 1700074P13 gene
chrM_+_9459 1.73 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr4_+_10874498 1.71 ENSMUST00000080517.14
RIKEN cDNA 2610301B20 gene
chr4_+_10874537 1.69 ENSMUST00000101504.3
RIKEN cDNA 2610301B20 gene
chr6_-_141892686 1.68 ENSMUST00000042119.6
solute carrier organic anion transporter family, member 1a1
chr13_+_100788087 1.67 ENSMUST00000190165.7
ENSMUST00000185767.7
TATA-box binding protein associated factor 9
chr9_+_64718596 1.67 ENSMUST00000038890.6
DENN/MADD domain containing 4A
chr2_-_134486039 1.66 ENSMUST00000038228.11
thioredoxin-related transmembrane protein 4
chr7_-_55669702 1.66 ENSMUST00000052204.6
non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
chrX_+_168468186 1.65 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr18_+_37138256 1.64 ENSMUST00000115658.6
protocadherin alpha 11
chr19_-_6191440 1.64 ENSMUST00000025893.7
ADP-ribosylation factor-like 2
chr11_-_70537878 1.63 ENSMUST00000014750.15
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr12_+_108145802 1.63 ENSMUST00000221167.2
cyclin K
chr2_-_134485936 1.62 ENSMUST00000110120.2
thioredoxin-related transmembrane protein 4
chr2_-_45000250 1.61 ENSMUST00000201211.4
ENSMUST00000177302.8
zinc finger E-box binding homeobox 2
chr8_-_68514879 1.57 ENSMUST00000212505.2
pleckstrin and Sec7 domain containing 3
chr9_+_108270020 1.57 ENSMUST00000035234.6
RIKEN cDNA 1700102P08 gene
chr10_-_79422946 1.55 ENSMUST00000077433.13
testicular haploid expressed gene
chr2_+_120459593 1.55 ENSMUST00000180041.9
START domain containing 9
chr13_-_95359955 1.55 ENSMUST00000159608.8
phosphodiesterase 8B
chr10_-_30531768 1.54 ENSMUST00000092610.12
nuclear receptor coactivator 7
chr5_+_20112704 1.51 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_76045696 1.51 ENSMUST00000144892.2
phosphodiesterase 11A
chrX_-_74886623 1.47 ENSMUST00000114057.8
plastin 3 (T-isoform)
chr18_-_43610829 1.47 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr6_-_141892517 1.45 ENSMUST00000168119.8
solute carrier organic anion transporter family, member 1a1
chr4_+_115641996 1.44 ENSMUST00000177280.8
ENSMUST00000176047.8
ATP synthase mitochondrial F1 complex assembly factor 1
chr7_+_50248918 1.44 ENSMUST00000119710.3
RIKEN cDNA 4933405O20 gene
chr9_+_108269992 1.43 ENSMUST00000192995.6
RIKEN cDNA 1700102P08 gene
chr1_+_179788675 1.43 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr6_-_55109826 1.41 ENSMUST00000164012.3
ENSMUST00000212633.2
corticotropin releasing hormone receptor 2
chr7_+_129193581 1.36 ENSMUST00000084519.7
WD repeat domain 11
chr3_+_20011251 1.36 ENSMUST00000108328.8
ceruloplasmin
chr2_-_134485999 1.35 ENSMUST00000110119.2
thioredoxin-related transmembrane protein 4
chr10_+_69761630 1.33 ENSMUST00000182029.8
ankyrin 3, epithelial
chr7_-_100581314 1.32 ENSMUST00000107032.3
Rho guanine nucleotide exchange factor (GEF) 17
chr2_-_77000936 1.31 ENSMUST00000164114.9
ENSMUST00000049544.14
coiled-coil domain containing 141
chr17_-_47922374 1.30 ENSMUST00000024783.9
bystin-like
chr4_+_108336164 1.28 ENSMUST00000155068.2
terminal uridylyl transferase 4
chr7_-_45343785 1.26 ENSMUST00000040636.9
secretory blood group 1
chr6_-_55109960 1.24 ENSMUST00000003568.15
corticotropin releasing hormone receptor 2
chr3_-_51184895 1.24 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr13_+_100787841 1.21 ENSMUST00000084721.8
ENSMUST00000190729.2
adenylate kinase 6
chr17_+_14087827 1.20 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr7_-_81216687 1.19 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr10_+_69761597 1.19 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
ankyrin 3, epithelial
chr13_+_55517545 1.19 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr7_-_127048280 1.19 ENSMUST00000053392.11
zinc finger protein 689
chr4_-_116565509 1.18 ENSMUST00000030453.5
methylmalonic aciduria cblC type, with homocystinuria
chr7_+_25016492 1.18 ENSMUST00000128119.2
multiple EGF-like-domains 8
chr16_-_58930996 1.17 ENSMUST00000076262.4
olfactory receptor 193
chr17_-_34962823 1.17 ENSMUST00000069507.9
complement component 4B (Chido blood group)
chr7_-_127048165 1.17 ENSMUST00000106299.2
zinc finger protein 689
chr7_+_5083212 1.13 ENSMUST00000098845.10
ENSMUST00000146317.8
ENSMUST00000153169.2
ENSMUST00000045277.7
epsin 1
chr6_-_122317156 1.11 ENSMUST00000159384.8
polyhomeotic 1
chr16_-_59459745 1.11 ENSMUST00000099646.10
ADP-ribosylation factor-like 6
chr1_-_170695328 1.09 ENSMUST00000027974.7
activating transcription factor 6
chr17_+_36152559 1.07 ENSMUST00000174124.2
mediator of DNA damage checkpoint 1
chr5_+_67125902 1.05 ENSMUST00000127184.8
LIM and calponin homology domains 1
chr9_+_64718708 1.04 ENSMUST00000213926.2
DENN/MADD domain containing 4A
chr6_-_68857658 1.00 ENSMUST00000198756.2
predicted gene 42543
chr17_+_36134398 1.00 ENSMUST00000173493.8
ENSMUST00000173147.8
flotillin 1
chr10_-_30531832 0.99 ENSMUST00000217138.2
ENSMUST00000217644.2
ENSMUST00000216172.2
nuclear receptor coactivator 7
chr1_+_171975625 0.98 ENSMUST00000191689.6
ENSMUST00000192704.6
ENSMUST00000074144.11
DDB1 and CUL4 associated factor 8
chr12_-_108145498 0.97 ENSMUST00000071095.14
SET domain containing 3
chr3_-_51184730 0.93 ENSMUST00000195432.2
ENSMUST00000091144.11
ENSMUST00000156983.3
E74-like factor 2
chrM_+_7758 0.91 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr11_-_69712970 0.89 ENSMUST00000045771.7
sperm maturation 1
chr7_+_101545547 0.88 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr10_-_13264574 0.87 ENSMUST00000079698.7
phosphatase and actin regulator 2
chrM_+_7779 0.87 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr8_-_43760017 0.85 ENSMUST00000082120.5
zinc finger protein 42
chr16_+_44215136 0.85 ENSMUST00000099742.9
cilia and flagella associated protein 44
chr12_-_86773160 0.85 ENSMUST00000021682.9
angel homolog 1
chr17_+_36152383 0.84 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr11_+_78717398 0.83 ENSMUST00000147875.9
ENSMUST00000141321.2
LYR motif containing 9
chr15_+_76264695 0.82 ENSMUST00000096385.11
ENSMUST00000160728.8
maestro heat-like repeat family member 1
chr5_-_5564730 0.82 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr2_-_29677634 0.79 ENSMUST00000177467.8
ENSMUST00000113807.10
TruB pseudouridine (psi) synthase family member 2
chr5_+_92535705 0.78 ENSMUST00000138687.2
ENSMUST00000124509.2
ADP-ribosyltransferase 3
chr4_+_109092459 0.78 ENSMUST00000106631.9
calreticulin 4
chr11_+_70861007 0.78 ENSMUST00000018593.10
RPA interacting protein
chr4_-_25242858 0.76 ENSMUST00000029922.14
ENSMUST00000108204.2
four and a half LIM domains 5
chr13_+_24054267 0.75 ENSMUST00000006785.8
solute carrier family 17 (sodium phosphate), member 1
chr12_-_44256843 0.74 ENSMUST00000220421.2
DnaJ heat shock protein family (Hsp40) member B9
chr2_-_31700592 0.74 ENSMUST00000057407.3
pyroglutamylated RFamide peptide
chr7_-_64522741 0.73 ENSMUST00000094331.5
NSE3 homolog, SMC5-SMC6 complex component
chr8_-_85696369 0.73 ENSMUST00000109736.9
ENSMUST00000140561.8
ribonuclease H2, large subunit
chr10_+_77697785 0.72 ENSMUST00000218443.2
predicted gene 3285
chr7_-_105282751 0.70 ENSMUST00000057525.14
tripartite motif-containing 3
chr2_-_77000878 0.70 ENSMUST00000111833.3
coiled-coil domain containing 141
chr18_+_65183987 0.69 ENSMUST00000236103.2
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr4_-_155445818 0.68 ENSMUST00000030922.15
protein kinase C, zeta
chr10_+_69761314 0.68 ENSMUST00000182692.8
ENSMUST00000092433.12
ankyrin 3, epithelial
chr7_-_29605949 0.68 ENSMUST00000159920.2
ENSMUST00000162592.8
zinc finger protein 27
chr16_-_22676264 0.68 ENSMUST00000232075.2
ENSMUST00000004576.8
TBCC domain containing 1
chr7_-_12829100 0.67 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr12_+_83567240 0.66 ENSMUST00000021645.9
DDB1 and CUL4 associated factor 4
chrX_+_149372903 0.66 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_123804745 0.65 ENSMUST00000149410.2
CAP-GLY domain containing linker protein 1
chr12_-_12990584 0.65 ENSMUST00000130990.2
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
chr8_+_25507227 0.63 ENSMUST00000033961.7
ENSMUST00000210536.2
TM2 domain containing 2
chr4_-_98705774 0.62 ENSMUST00000102790.4
KN motif and ankyrin repeat domains 4
chr1_+_37068429 0.61 ENSMUST00000162449.7
von Willebrand factor A domain containing 3B
chr6_+_115578863 0.59 ENSMUST00000000449.9
makorin, ring finger protein, 2
chrX_+_73352694 0.59 ENSMUST00000130581.2
guanosine diphosphate (GDP) dissociation inhibitor 1
chr19_+_36061096 0.59 ENSMUST00000025714.9
ribonuclease P/MRP 30 subunit
chr8_+_41128099 0.59 ENSMUST00000051614.5
a disintegrin and metallopeptidase domain 24 (testase 1)
chr2_+_85606930 0.57 ENSMUST00000076250.2
olfactory receptor 1014
chr3_+_5283606 0.57 ENSMUST00000026284.13
zinc finger homeodomain 4
chr11_-_104441218 0.56 ENSMUST00000106962.9
ENSMUST00000106961.2
ENSMUST00000093923.9
cell division cycle 27
chr11_+_70350436 0.55 ENSMUST00000039093.10
zinc finger, MYND-type containing 15
chr19_+_46140942 0.55 ENSMUST00000026254.14
golgi-specific brefeldin A-resistance factor 1
chr4_-_123507494 0.53 ENSMUST00000238866.2
microtubule-actin crosslinking factor 1
chr2_+_29533799 0.52 ENSMUST00000238899.2
Rap guanine nucleotide exchange factor (GEF) 1
chr11_-_93776580 0.51 ENSMUST00000066888.10
UTP18 small subunit processome component
chr12_+_83567303 0.51 ENSMUST00000222502.2
DDB1 and CUL4 associated factor 4
chr11_+_87684548 0.49 ENSMUST00000143021.9
myeloperoxidase
chr7_+_27878894 0.48 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr6_+_57086439 0.46 ENSMUST00000228270.2
vomeronasal 1 receptor 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.0 3.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.8 4.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.8 3.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.7 2.2 GO:0061193 taste bud development(GO:0061193)
0.7 5.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.7 4.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.7 4.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.7 2.7 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.6 7.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.6 4.6 GO:0035106 operant conditioning(GO:0035106)
0.5 2.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.5 5.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 2.5 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.5 3.0 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.4 4.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 4.4 GO:0015879 carnitine transport(GO:0015879)
0.4 1.8 GO:0080154 regulation of fertilization(GO:0080154)
0.4 1.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 2.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 6.1 GO:0071420 cellular response to histamine(GO:0071420)
0.3 2.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 3.5 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 5.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 3.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.6 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.2 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 4.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 0.5 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.2 7.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 7.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.6 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 2.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 2.8 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.1 3.7 GO:0046688 response to copper ion(GO:0046688)
0.1 2.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.8 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.3 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 2.1 GO:1990403 embryonic brain development(GO:1990403)
0.1 6.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 2.8 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 3.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 1.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.7 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1 3.1 GO:0035634 response to stilbenoid(GO:0035634)
0.1 2.5 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.4 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 3.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.6 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 6.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 2.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 3.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.6 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.6 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.6 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.7 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 2.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 12.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.7 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 2.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.7 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 2.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 2.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 2.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 4.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.3 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.9 GO:0030317 sperm motility(GO:0030317)
0.0 3.9 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 16.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.5 4.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.1 5.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.6 4.7 GO:0033269 internode region of axon(GO:0033269)
0.6 2.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.5 6.5 GO:0001739 sex chromatin(GO:0001739)
0.5 1.6 GO:0002944 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.4 7.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 2.8 GO:0008091 spectrin(GO:0008091)
0.3 1.7 GO:0000125 PCAF complex(GO:0000125)
0.3 4.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 1.8 GO:0002081 outer acrosomal membrane(GO:0002081)
0.2 1.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 6.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 2.2 GO:0042629 mast cell granule(GO:0042629)
0.2 2.7 GO:0070852 cell body fiber(GO:0070852)
0.1 3.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 3.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 4.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 3.7 GO:0097546 ciliary base(GO:0097546)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 3.3 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 2.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 3.5 GO:0031672 A band(GO:0031672)
0.1 2.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.2 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 2.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 3.6 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 1.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 5.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.3 GO:0097016 L27 domain binding(GO:0097016)
1.7 6.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.4 4.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.0 3.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.9 2.7 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.9 4.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.9 2.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.8 3.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.8 3.9 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.7 2.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.6 2.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 4.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 4.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.5 5.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 2.3 GO:0051373 FATZ binding(GO:0051373)
0.4 1.3 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.4 4.0 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 2.7 GO:0004630 phospholipase D activity(GO:0004630)
0.3 1.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 3.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 3.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 1.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 2.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 4.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 6.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 2.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.1 5.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 4.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 4.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 6.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 3.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.3 GO:0030332 cyclin binding(GO:0030332)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 5.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 3.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 6.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.3 GO:0070404 NADH binding(GO:0070404)
0.0 3.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.4 ST GA12 PATHWAY G alpha 12 Pathway
0.1 6.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.9 PID ATM PATHWAY ATM pathway
0.0 1.7 PID MYC PATHWAY C-MYC pathway
0.0 2.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 4.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 3.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 6.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 6.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.0 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 6.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 6.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 6.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 7.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 7.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)