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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Cebpa_Cebpg

Z-value: 1.94

Motif logo

Transcription factors associated with Cebpa_Cebpg

Gene Symbol Gene ID Gene Info
ENSMUSG00000034957.11 Cebpa
ENSMUSG00000056216.10 Cebpg

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpamm39_v1_chr7_+_34818709_348187280.632.2e-09Click!
Cebpgmm39_v1_chr7_-_34755985_347560020.047.1e-01Click!

Activity profile of Cebpa_Cebpg motif

Sorted Z-values of Cebpa_Cebpg motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_22710785 38.50 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr3_+_20011201 33.97 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr14_+_75479727 32.30 ENSMUST00000022576.10
carboxypeptidase B2 (plasma)
chr16_+_22877000 31.01 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
kininogen 1
chr3_+_20011251 30.35 ENSMUST00000108328.8
ceruloplasmin
chr3_+_20011405 29.31 ENSMUST00000108325.9
ceruloplasmin
chr16_-_22847808 25.45 ENSMUST00000115349.9
kininogen 2
chr16_-_22847760 23.19 ENSMUST00000039338.13
kininogen 2
chr12_-_81014849 22.52 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr17_-_56428968 22.43 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr16_-_22847829 20.99 ENSMUST00000100046.9
kininogen 2
chr12_-_81014755 19.44 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr10_+_23727325 19.28 ENSMUST00000020190.8
vanin 3
chr7_+_46401214 17.01 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr16_-_22848153 16.78 ENSMUST00000232459.2
kininogen 2
chr6_+_37507108 16.53 ENSMUST00000040987.11
aldo-keto reductase family 1, member D1
chr7_+_26534730 16.43 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr7_-_103463120 15.94 ENSMUST00000098192.4
hemoglobin, beta adult t chain
chr4_+_63262775 14.73 ENSMUST00000030044.3
orosomucoid 1
chr11_+_3981769 14.72 ENSMUST00000019512.8
SEC14-like lipid binding 4
chr7_+_13467422 13.46 ENSMUST00000086148.8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr17_-_57535003 13.02 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3
chr16_-_30086317 12.22 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr19_-_7779943 12.04 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr10_+_21253190 11.75 ENSMUST00000042699.14
aldehyde dehydrogenase 8 family, member A1
chr11_+_108286114 11.19 ENSMUST00000000049.6
apolipoprotein H
chr19_-_38113696 11.15 ENSMUST00000025951.14
ENSMUST00000237287.2
retinol binding protein 4, plasma
chr6_+_141575226 11.14 ENSMUST00000042812.9
solute carrier organic anion transporter family, member 1b2
chr6_+_17463748 10.76 ENSMUST00000115443.8
met proto-oncogene
chr9_+_21746785 10.73 ENSMUST00000058777.8
angiopoietin-like 8
chr5_-_104125270 10.55 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr5_-_104125192 10.46 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr14_+_66208498 10.10 ENSMUST00000128539.8
clusterin
chr14_+_66208059 9.88 ENSMUST00000127387.8
clusterin
chr5_-_104125226 9.69 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chrX_+_59044796 9.37 ENSMUST00000033477.5
coagulation factor IX
chr7_+_27147403 9.32 ENSMUST00000037399.16
ENSMUST00000108358.8
biliverdin reductase B (flavin reductase (NADPH))
chr6_-_141892686 9.12 ENSMUST00000042119.6
solute carrier organic anion transporter family, member 1a1
chr2_-_32277773 9.05 ENSMUST00000050785.14
lipocalin 2
chr10_+_93324624 9.05 ENSMUST00000129421.8
histidine ammonia lyase
chr5_+_90708962 9.04 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr14_+_66208613 8.92 ENSMUST00000144619.2
clusterin
chr4_+_63280675 8.87 ENSMUST00000075341.4
orosomucoid 2
chr16_-_93726399 8.67 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr7_+_127399776 8.17 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr6_-_141892517 8.16 ENSMUST00000168119.8
solute carrier organic anion transporter family, member 1a1
chr14_+_66208253 8.14 ENSMUST00000138191.8
clusterin
chr19_-_7780025 8.08 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr2_-_32278245 7.55 ENSMUST00000192241.2
lipocalin 2
chr7_-_46365108 7.49 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr7_+_13357892 7.42 ENSMUST00000108525.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr2_+_102536701 7.37 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_124519240 7.31 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr9_+_107957621 6.80 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_107957640 6.55 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_172994841 6.33 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr8_+_46924074 6.16 ENSMUST00000034046.13
ENSMUST00000211644.2
acyl-CoA synthetase long-chain family member 1
chr6_-_3968365 6.07 ENSMUST00000031674.11
tissue factor pathway inhibitor 2
chr6_+_17463819 6.05 ENSMUST00000140070.8
met proto-oncogene
chr14_+_44340111 5.96 ENSMUST00000074839.7
eosinophil-associated, ribonuclease A family, member 2
chr18_+_21077627 5.75 ENSMUST00000050004.3
ring finger protein 125
chr6_+_129374441 5.75 ENSMUST00000112081.9
ENSMUST00000112079.3
C-type lectin domain family 1, member b
chr17_-_57501170 5.61 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr11_-_43792013 5.60 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chr7_-_45109262 5.60 ENSMUST00000094434.13
ferritin light polypeptide 1
chr7_-_13571334 5.48 ENSMUST00000108522.5
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr7_-_126873219 5.37 ENSMUST00000082428.6
selenophosphate synthetase 2
chr15_-_55770118 5.23 ENSMUST00000110200.3
syntrophin, basic 1
chr15_+_31224460 5.22 ENSMUST00000044524.16
death-associated protein
chr14_-_44057096 4.64 ENSMUST00000100691.4
eosinophil-associated, ribonuclease A family, member 1
chr9_+_110248815 4.60 ENSMUST00000035061.9
neutrophilic granule protein
chr13_+_47347301 4.54 ENSMUST00000110111.4
ring finger protein 144B
chr7_-_45109075 4.50 ENSMUST00000210864.2
ferritin light polypeptide 1
chr15_+_100202642 4.46 ENSMUST00000067752.5
ENSMUST00000229588.2
methyltransferase like 7A1
chr2_-_129213050 4.27 ENSMUST00000028881.14
interleukin 1 beta
chr2_-_32314017 4.22 ENSMUST00000113307.9
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr15_+_31224616 4.14 ENSMUST00000186547.7
death-associated protein
chr19_-_11618165 4.01 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr19_-_11618192 3.99 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chr7_+_51530060 3.98 ENSMUST00000145049.2
growth arrest specific 2
chr15_+_31224555 3.91 ENSMUST00000186109.2
death-associated protein
chr7_+_27147475 3.90 ENSMUST00000133750.8
biliverdin reductase B (flavin reductase (NADPH))
chr17_+_57665691 3.77 ENSMUST00000086763.13
ENSMUST00000233376.2
ENSMUST00000233840.2
ENSMUST00000232808.2
ENSMUST00000004850.8
adhesion G protein-coupled receptor E1
chr19_-_34855278 3.74 ENSMUST00000112460.3
pantothenate kinase 1
chr15_-_76191301 3.71 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr15_+_31225302 3.70 ENSMUST00000186425.7
death-associated protein
chr1_+_130793406 3.61 ENSMUST00000038829.7
Fc fragment of IgM receptor
chr10_+_5543769 3.53 ENSMUST00000051809.10
myc target 1
chr7_-_120673761 3.52 ENSMUST00000047194.4
immunoglobulin superfamily, member 6
chr1_+_74414354 3.46 ENSMUST00000187516.7
ENSMUST00000027368.6
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr5_-_137856280 3.43 ENSMUST00000110978.7
ENSMUST00000199387.2
ENSMUST00000196195.2
paired immunoglobin-like type 2 receptor beta 1
chr1_+_134110142 3.31 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr16_-_38253507 3.23 ENSMUST00000002926.8
phospholipase A1 member A
chr19_-_34855242 3.05 ENSMUST00000238065.2
pantothenate kinase 1
chr14_-_44112974 2.94 ENSMUST00000179200.2
eosinophil-associated, ribonuclease A family, member 1
chr14_+_52091156 2.92 ENSMUST00000169070.2
ENSMUST00000074477.7
eosinophil-associated, ribonuclease A family, member 6
chr2_-_45007407 2.87 ENSMUST00000176438.9
zinc finger E-box binding homeobox 2
chr3_-_116762476 2.83 ENSMUST00000119557.8
palmdelphin
chr1_-_39616445 2.66 ENSMUST00000062525.11
ring finger protein 149
chr1_+_40554513 2.65 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chr4_+_114916703 2.62 ENSMUST00000162489.2
T cell acute lymphocytic leukemia 1
chr6_+_72281587 2.58 ENSMUST00000183018.8
ENSMUST00000182014.10
surfactant associated protein B
chr5_-_88823989 2.55 ENSMUST00000078945.12
G-rich RNA sequence binding factor 1
chr7_-_15978077 2.53 ENSMUST00000238893.2
ENSMUST00000171425.4
complement component 5a receptor 2
chr16_+_42727926 2.52 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr2_-_143853122 2.52 ENSMUST00000016072.12
ENSMUST00000037875.6
ribosome binding protein 1
chr13_+_51254852 2.43 ENSMUST00000095797.6
spindlin 1
chr9_+_7571397 2.38 ENSMUST00000120900.8
ENSMUST00000151853.8
ENSMUST00000152878.3
matrix metallopeptidase 27
chr5_-_137869969 2.38 ENSMUST00000196162.5
paired immunoglobin-like type 2 receptor beta 2
chr1_-_39616369 2.29 ENSMUST00000195705.2
ring finger protein 149
chr14_-_44161016 2.27 ENSMUST00000159175.2
eosinophil-associated, ribonuclease A family, member 10
chr5_-_18093739 2.20 ENSMUST00000169095.6
ENSMUST00000197574.2
CD36 molecule
chr8_-_41507808 2.18 ENSMUST00000093534.11
mitochondrial tumor suppressor 1
chr5_-_137870001 2.08 ENSMUST00000164886.2
paired immunoglobin-like type 2 receptor beta 2
chrX_+_108240356 1.92 ENSMUST00000139259.2
ENSMUST00000060013.4
predicted gene 6377
chr15_-_103218876 1.85 ENSMUST00000079824.6
G protein-coupled receptor 84
chr14_-_45715308 1.83 ENSMUST00000141424.2
fermitin family member 2
chr8_-_96615138 1.83 ENSMUST00000034097.8
glutamatic-oxaloacetic transaminase 2, mitochondrial
chr12_+_98234884 1.82 ENSMUST00000075072.6
G-protein coupled receptor 65
chr13_-_61084358 1.78 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr14_+_31887739 1.74 ENSMUST00000111994.10
ENSMUST00000168114.8
ENSMUST00000168034.8
nuclear receptor coactivator 4
chr13_+_25127127 1.71 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr11_+_40624466 1.70 ENSMUST00000020578.11
NudC domain containing 2
chr18_-_33346885 1.63 ENSMUST00000025236.9
StAR-related lipid transfer (START) domain containing 4
chr12_-_113542610 1.63 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr4_-_132459762 1.51 ENSMUST00000045550.5
X-linked Kx blood group related 8
chr11_-_83540175 1.44 ENSMUST00000001008.6
chemokine (C-C motif) ligand 3
chr3_-_107893676 1.42 ENSMUST00000066530.7
ENSMUST00000012348.9
glutathione S-transferase, mu 2
chr15_+_102379621 1.38 ENSMUST00000229918.2
poly(rC) binding protein 2
chr17_+_37253802 1.38 ENSMUST00000040498.12
ring finger protein 39
chr11_+_40624763 1.34 ENSMUST00000127382.2
NudC domain containing 2
chr11_-_106811185 1.33 ENSMUST00000167787.2
ENSMUST00000092517.9
SMAD specific E3 ubiquitin protein ligase 2
chr3_+_31956656 1.31 ENSMUST00000119310.8
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr12_+_86781154 1.30 ENSMUST00000095527.6
leucine rich repeat containing 74A
chr10_+_100428212 1.28 ENSMUST00000187119.7
ENSMUST00000188736.7
ENSMUST00000191336.7
RIKEN cDNA 1700017N19 gene
chr11_+_4014841 1.27 ENSMUST00000068322.7
SEC14-like lipid binding 3
chr18_-_33346819 1.27 ENSMUST00000119991.8
ENSMUST00000118990.2
StAR-related lipid transfer (START) domain containing 4
chr15_+_102379503 1.26 ENSMUST00000229222.2
poly(rC) binding protein 2
chr6_-_42524521 1.21 ENSMUST00000217978.2
olfactory receptor 455
chr15_+_6673167 1.19 ENSMUST00000163073.2
FYN binding protein
chr2_-_151815307 1.17 ENSMUST00000109863.2
family with sequence similarity 110, member A
chr15_-_98278827 1.16 ENSMUST00000215830.2
olfactory receptor 283
chr2_-_160714749 1.16 ENSMUST00000176141.8
zinc fingers and homeoboxes 3
chr11_-_66059270 1.16 ENSMUST00000108691.2
dynein, axonemal, heavy chain 9
chr13_+_23930717 1.16 ENSMUST00000099703.5
H2B clustered histone 3
chr3_+_31956814 1.10 ENSMUST00000192429.6
ENSMUST00000191869.6
ENSMUST00000178668.2
ENSMUST00000119970.8
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr7_+_28136861 1.07 ENSMUST00000108292.9
ENSMUST00000108289.8
glia maturation factor, gamma
chr4_+_155646807 1.07 ENSMUST00000030939.14
NAD kinase
chr4_-_15149051 1.04 ENSMUST00000041606.14
N-terminal EF-hand calcium binding protein 1
chr7_-_133304244 1.04 ENSMUST00000209636.2
ENSMUST00000153698.3
uroporphyrinogen III synthase
chr2_+_172090412 1.04 ENSMUST00000038532.2
melanocortin 3 receptor
chr15_-_101361632 1.02 ENSMUST00000061185.8
keratin 81
chr11_-_105347500 1.00 ENSMUST00000049995.10
ENSMUST00000100332.4
membrane associated ring-CH-type finger 10
chr13_-_53135064 0.99 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr2_-_52566583 0.98 ENSMUST00000178799.8
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_160714904 0.98 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr18_+_37397991 0.98 ENSMUST00000052366.5
protocadherin beta 1
chr12_+_100745314 0.97 ENSMUST00000069782.11
D-glutamate cyclase
chr14_+_51181956 0.96 ENSMUST00000178092.2
ENSMUST00000227052.2
purine-nucleoside phosphorylase
predicted gene, 49342
chr11_-_84761538 0.95 ENSMUST00000170741.2
ENSMUST00000172405.8
ENSMUST00000100686.10
ENSMUST00000108081.9
gametogenetin binding protein 2
chr15_+_102012782 0.95 ENSMUST00000230474.2
tensin 2
chr7_-_46392403 0.90 ENSMUST00000128088.4
serum amyloid A 1
chr6_+_30401864 0.89 ENSMUST00000068240.13
ENSMUST00000068259.10
ENSMUST00000132581.8
kelch domain containing 10
chr17_+_37253916 0.88 ENSMUST00000173072.2
ring finger protein 39
chr17_+_28910302 0.86 ENSMUST00000004990.14
ENSMUST00000114754.8
ENSMUST00000062694.16
mitogen-activated protein kinase 14
chr2_-_152673585 0.86 ENSMUST00000156688.2
ENSMUST00000007803.12
BCL2-like 1
chr3_-_63872189 0.85 ENSMUST00000029402.15
solute carrier family 33 (acetyl-CoA transporter), member 1
chr7_+_78563513 0.83 ENSMUST00000038142.15
interferon-stimulated protein
chr12_+_100745333 0.83 ENSMUST00000110073.8
ENSMUST00000110069.8
D-glutamate cyclase
chr5_-_147831610 0.82 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
solute carrier family 46, member 3
chr17_+_28910393 0.80 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chrX_-_103244728 0.80 ENSMUST00000056502.7
neurite extension and migration factor
chr10_+_100428246 0.77 ENSMUST00000041162.13
ENSMUST00000190386.7
ENSMUST00000190708.7
RIKEN cDNA 1700017N19 gene
chr15_+_44482944 0.76 ENSMUST00000022964.9
estrogen receptor-binding fragment-associated gene 9
chr8_-_56359983 0.75 ENSMUST00000053441.5
a disintegrin and metallopeptidase domain 29
chr3_-_107993906 0.73 ENSMUST00000102638.8
ENSMUST00000102637.8
adenosine monophosphate deaminase 2
chr17_+_29712008 0.71 ENSMUST00000234665.2
proviral integration site 1
chr6_+_40470463 0.69 ENSMUST00000038750.7
taste receptor, type 2, member 108
chr7_-_130931235 0.69 ENSMUST00000188899.2
family with sequence similarity 24 member B
chr14_-_36770898 0.67 ENSMUST00000225070.2
ENSMUST00000022338.7
retinal G protein coupled receptor
chrX_-_103244784 0.67 ENSMUST00000118314.8
neurite extension and migration factor
chr10_-_88192852 0.65 ENSMUST00000020249.2
DNA-damage regulated autophagy modulator 1
chr7_-_25112256 0.65 ENSMUST00000200880.4
ENSMUST00000074040.4
chemokine (C-X-C motif) ligand 17
chr8_+_95781722 0.63 ENSMUST00000058479.7
dynein regulatory complex subunit 7
chr8_+_95055829 0.63 ENSMUST00000034218.5
ENSMUST00000212134.2
solute carrier family 12, member 3
chr11_-_84761472 0.63 ENSMUST00000018547.9
gametogenetin binding protein 2
chr5_+_145077172 0.62 ENSMUST00000162594.8
ENSMUST00000162308.8
ENSMUST00000159018.8
ENSMUST00000160075.2
BUD31 homolog
chr13_-_57043550 0.61 ENSMUST00000022023.13
ENSMUST00000174457.9
ENSMUST00000109871.8
transient receptor potential cation channel, subfamily C, member 7
chr11_-_66059330 0.58 ENSMUST00000080665.10
dynein, axonemal, heavy chain 9
chr6_+_83055321 0.57 ENSMUST00000165164.9
ENSMUST00000092614.9
polycomb group ring finger 1
chr4_+_152123772 0.56 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr12_-_105188993 0.55 ENSMUST00000041316.15
T cell lymphoma breakpoint 1
chr15_+_44482667 0.54 ENSMUST00000228648.2
ENSMUST00000226165.2
estrogen receptor-binding fragment-associated gene 9
chr7_-_45264908 0.54 ENSMUST00000033099.6
fibroblast growth factor 21
chr4_+_130001349 0.54 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr11_-_102120917 0.54 ENSMUST00000008999.12
histone deacetylase 5
chr7_-_28078671 0.53 ENSMUST00000209061.2
zinc finger protein 36
chr11_-_84761637 0.53 ENSMUST00000168434.8
gametogenetin binding protein 2
chr6_+_83055581 0.52 ENSMUST00000177177.8
ENSMUST00000176089.2
polycomb group ring finger 1
chr10_-_128885867 0.52 ENSMUST00000216460.2
olfactory receptor 765

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 32.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
6.2 37.0 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
5.5 16.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
5.5 16.5 GO:0030573 bile acid catabolic process(GO:0030573)
3.4 16.8 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
3.3 13.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
2.8 11.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.5 93.6 GO:0006825 copper ion transport(GO:0006825) response to copper ion(GO:0046688)
2.2 11.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.9 5.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.9 5.6 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
1.8 60.4 GO:0035634 response to stilbenoid(GO:0035634)
1.8 9.1 GO:0006548 histidine catabolic process(GO:0006548)
1.8 10.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.7 13.2 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.6 53.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.6 6.3 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.5 98.9 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
1.5 13.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
1.4 2.9 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
1.4 4.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.3 20.1 GO:0015747 urate transport(GO:0015747)
1.3 11.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.3 2.5 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
1.2 3.5 GO:0070839 divalent metal ion export(GO:0070839)
1.2 4.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.1 62.7 GO:0006953 acute-phase response(GO:0006953)
1.1 7.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 10.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.9 1.8 GO:0006533 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.9 2.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.9 1.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.8 8.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 5.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.6 6.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.5 22.4 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.5 19.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.4 2.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 1.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.4 6.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.4 1.1 GO:0071846 actin filament debranching(GO:0071846)
0.4 2.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.0 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.3 1.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 17.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.3 2.4 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 5.5 GO:0051923 sulfation(GO:0051923)
0.2 1.4 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 30.7 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.2 0.9 GO:0046898 response to cycloheximide(GO:0046898)
0.2 1.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.6 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 3.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 0.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 0.5 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.2 5.2 GO:0014823 response to activity(GO:0014823)
0.2 3.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.7 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.5 GO:0090208 positive regulation of triglyceride metabolic process(GO:0090208)
0.1 1.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 5.7 GO:0030220 platelet formation(GO:0030220)
0.1 2.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 2.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 3.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 1.8 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.5 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 2.4 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.8 GO:0033622 integrin activation(GO:0033622)
0.1 12.2 GO:0007596 blood coagulation(GO:0007596)
0.1 1.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 7.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 1.8 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 3.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 3.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 1.0 GO:0001659 temperature homeostasis(GO:0001659)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.4 GO:2000741 regulation of mesenchymal stem cell differentiation(GO:2000739) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 9.0 GO:0008202 steroid metabolic process(GO:0008202)
0.0 2.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 2.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.0 1.7 GO:0003341 cilium movement(GO:0003341)
0.0 1.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 3.0 GO:0006457 protein folding(GO:0006457)
0.0 0.5 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.6 GO:0009952 anterior/posterior pattern specification(GO:0009952)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 15.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
2.5 37.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.5 38.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.3 90.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.9 2.6 GO:0033193 Lsd1/2 complex(GO:0033193)
0.7 11.8 GO:0044754 autolysosome(GO:0044754)
0.7 183.5 GO:0072562 blood microparticle(GO:0072562)
0.7 3.5 GO:0030312 external encapsulating structure(GO:0030312)
0.3 2.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 35.2 GO:0005811 lipid particle(GO:0005811)
0.3 2.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 16.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 51.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 14.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 13.2 GO:0043195 terminal bouton(GO:0043195)
0.1 6.8 GO:0030118 clathrin coat(GO:0030118)
0.1 1.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 6.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 8.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 72.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 7.4 GO:0043197 dendritic spine(GO:0043197)
0.0 1.7 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 4.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 4.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 4.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 93.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
6.4 38.5 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
5.2 42.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
4.4 13.2 GO:0042602 riboflavin reductase (NADPH) activity(GO:0042602)
4.2 16.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
4.0 15.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
3.7 11.2 GO:0034632 retinol transporter activity(GO:0034632)
3.3 16.5 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
2.1 6.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.0 8.2 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
2.0 12.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.9 11.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.8 5.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.4 37.0 GO:0051787 misfolded protein binding(GO:0051787)
1.4 5.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.3 9.1 GO:0016841 ammonia-lyase activity(GO:0016841)
1.2 11.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.2 6.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
1.2 7.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 20.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.1 6.8 GO:0004594 pantothenate kinase activity(GO:0004594)
1.1 32.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.0 120.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.0 17.0 GO:0070513 death domain binding(GO:0070513)
0.9 7.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.8 2.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.8 11.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 1.8 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.5 17.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5 3.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 17.9 GO:0042056 chemoattractant activity(GO:0042056)
0.4 1.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 16.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.4 2.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 3.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 4.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 23.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 1.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 7.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 1.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 2.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 13.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 1.7 GO:0004630 phospholipase D activity(GO:0004630)
0.2 2.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 3.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 10.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 1.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 3.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 13.9 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 26.7 GO:0005506 iron ion binding(GO:0005506)
0.1 30.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 15.8 GO:0004540 ribonuclease activity(GO:0004540)
0.1 2.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 2.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 2.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.7 GO:0008061 chitin binding(GO:0008061)
0.1 1.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.8 GO:0009975 cyclase activity(GO:0009975)
0.1 2.1 GO:0008009 chemokine activity(GO:0008009)
0.0 1.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 14.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 5.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 3.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 13.2 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 44.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.8 90.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.6 39.8 PID BMP PATHWAY BMP receptor signaling
0.4 40.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 30.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.3 4.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 6.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 14.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 5.4 PID E2F PATHWAY E2F transcription factor network
0.1 1.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 8.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 42.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
2.3 97.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.9 24.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.8 40.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.9 13.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 14.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 6.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 6.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 5.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 16.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 39.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 6.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 8.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 5.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 6.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 4.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.9 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 2.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 5.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation