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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Cebpb

Z-value: 2.97

Motif logo

Transcription factors associated with Cebpb

Gene Symbol Gene ID Gene Info
ENSMUSG00000056501.4 Cebpb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpbmm39_v1_chr2_+_167530835_1675308940.641.3e-09Click!

Activity profile of Cebpb motif

Sorted Z-values of Cebpb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_93324624 42.67 ENSMUST00000129421.8
histidine ammonia lyase
chr16_+_22877000 39.25 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
kininogen 1
chr10_+_23727325 37.02 ENSMUST00000020190.8
vanin 3
chr3_+_82915031 33.09 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr16_+_22710785 30.25 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr11_+_69983459 30.03 ENSMUST00000102572.8
asialoglycoprotein receptor 2
chr14_+_40827108 28.79 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr3_+_82933383 27.99 ENSMUST00000029630.15
ENSMUST00000166581.4
fibrinogen alpha chain
chr11_+_69983479 26.54 ENSMUST00000143772.8
asialoglycoprotein receptor 2
chr14_+_40827317 25.83 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr4_+_63262775 25.73 ENSMUST00000030044.3
orosomucoid 1
chr14_+_51328534 24.69 ENSMUST00000022428.13
ENSMUST00000171688.9
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr9_-_71070506 24.16 ENSMUST00000074465.9
aquaporin 9
chr14_+_40826970 23.58 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr5_-_124003553 23.24 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr14_+_75479727 23.17 ENSMUST00000022576.10
carboxypeptidase B2 (plasma)
chr6_-_124519240 22.71 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr12_-_81014849 22.37 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr1_+_67162176 22.34 ENSMUST00000027144.8
carbamoyl-phosphate synthetase 1
chrX_+_59044796 21.72 ENSMUST00000033477.5
coagulation factor IX
chr11_+_69983531 21.24 ENSMUST00000124721.2
asialoglycoprotein receptor 2
chr19_-_38113249 20.81 ENSMUST00000112335.4
retinol binding protein 4, plasma
chr17_-_56428968 19.82 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr19_-_38113056 19.76 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr9_+_107957621 19.76 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_3968365 19.01 ENSMUST00000031674.11
tissue factor pathway inhibitor 2
chr12_-_81014755 18.94 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr19_-_38113696 18.85 ENSMUST00000025951.14
ENSMUST00000237287.2
retinol binding protein 4, plasma
chr9_+_107957640 18.68 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr12_+_104304631 18.65 ENSMUST00000043058.5
ENSMUST00000101078.12
serine (or cysteine) peptidase inhibitor, clade A, member 3K
serine (or cysteine) peptidase inhibitor, clade A, member 3M
chr11_-_75313412 18.58 ENSMUST00000138661.8
ENSMUST00000000769.14
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr9_-_103107460 18.25 ENSMUST00000165296.8
ENSMUST00000112645.8
transferrin
chr6_+_37507108 17.83 ENSMUST00000040987.11
aldo-keto reductase family 1, member D1
chr9_-_103107495 17.66 ENSMUST00000035158.16
transferrin
chr11_-_75313350 17.33 ENSMUST00000125982.2
ENSMUST00000137103.8
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr5_-_104125270 16.05 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr5_-_104125192 15.99 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr12_+_8027640 15.94 ENSMUST00000171271.8
ENSMUST00000037811.13
apolipoprotein B
chr12_+_8027767 15.87 ENSMUST00000037520.14
apolipoprotein B
chr7_+_27147403 15.20 ENSMUST00000037399.16
ENSMUST00000108358.8
biliverdin reductase B (flavin reductase (NADPH))
chr2_+_24235300 15.12 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr16_+_37400500 15.08 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr1_-_162726234 14.88 ENSMUST00000111510.8
ENSMUST00000045902.13
flavin containing monooxygenase 2
chr16_+_37400590 14.64 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr3_-_89820451 14.56 ENSMUST00000029559.7
ENSMUST00000197679.5
interleukin 6 receptor, alpha
chr6_+_17463748 14.55 ENSMUST00000115443.8
met proto-oncogene
chr9_-_109678685 14.45 ENSMUST00000112022.5
cathelicidin antimicrobial peptide
chr4_+_63280675 14.29 ENSMUST00000075341.4
orosomucoid 2
chr7_+_30463175 14.23 ENSMUST00000165887.8
ENSMUST00000085691.11
ENSMUST00000054427.13
ENSMUST00000085688.11
dermokine
chr3_+_20011201 14.22 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr10_+_62860291 14.16 ENSMUST00000020262.5
phenazine biosynthesis-like protein domain containing 2
chr11_-_99383938 13.99 ENSMUST00000006969.8
keratin 23
chr16_+_90535212 13.95 ENSMUST00000038197.3
melanocortin 2 receptor accessory protein
chr5_-_104125226 13.90 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr7_-_45109262 13.78 ENSMUST00000094434.13
ferritin light polypeptide 1
chr8_+_75820240 13.77 ENSMUST00000005548.8
heme oxygenase 1
chr8_+_46924074 13.76 ENSMUST00000034046.13
ENSMUST00000211644.2
acyl-CoA synthetase long-chain family member 1
chr19_+_55240357 13.71 ENSMUST00000225551.2
acyl-CoA synthetase long-chain family member 5
chr3_+_20011251 13.70 ENSMUST00000108328.8
ceruloplasmin
chr7_+_46401214 13.69 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr7_-_45109075 13.49 ENSMUST00000210864.2
ferritin light polypeptide 1
chr4_-_130068902 13.41 ENSMUST00000105998.8
tubulointerstitial nephritis antigen-like 1
chr5_+_8010445 13.37 ENSMUST00000115421.3
STEAP family member 4
chr2_-_164198427 13.22 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr8_-_34419826 12.85 ENSMUST00000033995.14
ENSMUST00000033994.15
ENSMUST00000191473.7
ENSMUST00000053251.12
RNA binding protein gene with multiple splicing
chr16_-_22847808 12.81 ENSMUST00000115349.9
kininogen 2
chr17_+_37253802 12.54 ENSMUST00000040498.12
ring finger protein 39
chr14_-_55950939 12.34 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr10_+_62860094 12.28 ENSMUST00000124784.8
phenazine biosynthesis-like protein domain containing 2
chr7_+_27147475 12.19 ENSMUST00000133750.8
biliverdin reductase B (flavin reductase (NADPH))
chr16_-_22847760 12.13 ENSMUST00000039338.13
kininogen 2
chr14_-_55950545 11.89 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr17_+_57665691 11.88 ENSMUST00000086763.13
ENSMUST00000233376.2
ENSMUST00000233840.2
ENSMUST00000232808.2
ENSMUST00000004850.8
adhesion G protein-coupled receptor E1
chr7_+_13467422 11.66 ENSMUST00000086148.8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr1_-_162726053 11.62 ENSMUST00000143123.3
flavin containing monooxygenase 2
chr9_-_48516447 11.61 ENSMUST00000034808.12
ENSMUST00000119426.2
nicotinamide N-methyltransferase
chr3_+_20011405 11.28 ENSMUST00000108325.9
ceruloplasmin
chr17_-_74257164 11.00 ENSMUST00000024866.6
xanthine dehydrogenase
chr3_+_106393348 10.91 ENSMUST00000183271.2
DENN/MADD domain containing 2D
chr7_-_28078671 10.89 ENSMUST00000209061.2
zinc finger protein 36
chr15_-_101848689 10.76 ENSMUST00000023799.8
keratin 79
chr16_-_22847829 10.69 ENSMUST00000100046.9
kininogen 2
chr2_-_32277773 10.64 ENSMUST00000050785.14
lipocalin 2
chr9_+_21746785 10.39 ENSMUST00000058777.8
angiopoietin-like 8
chr6_+_72281587 10.13 ENSMUST00000183018.8
ENSMUST00000182014.10
surfactant associated protein B
chr2_+_158148413 9.88 ENSMUST00000109491.8
ENSMUST00000016168.9
lipopolysaccharide binding protein
chr9_+_110248815 9.38 ENSMUST00000035061.9
neutrophilic granule protein
chr6_+_17463819 9.26 ENSMUST00000140070.8
met proto-oncogene
chr7_-_44181477 9.17 ENSMUST00000098483.9
ENSMUST00000035323.6
Spi-B transcription factor (Spi-1/PU.1 related)
chr9_+_110867807 9.16 ENSMUST00000197575.2
lactotransferrin
chr13_+_25127127 9.15 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr15_+_25940859 9.00 ENSMUST00000226750.2
reticulophagy regulator 1
chr2_-_110144869 8.99 ENSMUST00000133608.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr4_-_107928567 8.92 ENSMUST00000106701.2
sterol carrier protein 2, liver
chr7_-_46365108 8.90 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr3_+_84573499 8.86 ENSMUST00000107682.2
transmembrane protein 154
chr16_+_45044678 8.83 ENSMUST00000102802.10
ENSMUST00000063654.6
B and T lymphocyte associated
chr1_+_74414354 8.80 ENSMUST00000187516.7
ENSMUST00000027368.6
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr17_+_37253916 8.77 ENSMUST00000173072.2
ring finger protein 39
chr11_-_99280177 8.76 ENSMUST00000103131.5
keratin 10
chr14_+_51181956 8.65 ENSMUST00000178092.2
ENSMUST00000227052.2
purine-nucleoside phosphorylase
predicted gene, 49342
chr14_-_68893253 8.41 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr2_-_152185901 8.38 ENSMUST00000040312.7
tribbles pseudokinase 3
chr16_-_22848153 8.27 ENSMUST00000232459.2
kininogen 2
chr15_-_103161237 8.18 ENSMUST00000154510.8
nuclear factor, erythroid derived 2
chr5_+_91222470 8.18 ENSMUST00000031324.6
epiregulin
chr10_-_66932685 7.96 ENSMUST00000020023.9
receptor accessory protein 3
chr6_+_34686543 7.81 ENSMUST00000031775.13
caldesmon 1
chrX_-_166047275 7.72 ENSMUST00000112170.2
toll-like receptor 8
chrX_-_137985960 7.70 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr18_+_20643325 7.67 ENSMUST00000070892.8
ENSMUST00000234945.2
desmoglein 3
chr16_+_57369595 7.62 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr16_-_93726399 7.56 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr1_+_164624200 7.41 ENSMUST00000027861.6
dermatopontin
chr19_+_33985684 7.39 ENSMUST00000225505.2
lipase, family member K
chr1_-_131204651 7.16 ENSMUST00000161764.8
inhibitor of kappaB kinase epsilon
chr19_-_34724689 7.05 ENSMUST00000009522.4
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr19_+_33985701 7.02 ENSMUST00000054260.8
lipase, family member K
chr3_-_59102517 6.96 ENSMUST00000200095.2
G protein-coupled receptor 87
chr19_-_11618192 6.66 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chr16_+_57173456 6.66 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr6_-_87786736 6.60 ENSMUST00000032134.9
RAB43, member RAS oncogene family
chr1_-_131204422 6.53 ENSMUST00000159195.2
inhibitor of kappaB kinase epsilon
chr6_+_115398996 6.51 ENSMUST00000000450.5
peroxisome proliferator activated receptor gamma
chr10_-_127358300 6.51 ENSMUST00000026470.6
serine hydroxymethyltransferase 2 (mitochondrial)
chr15_+_25940912 6.51 ENSMUST00000226438.2
reticulophagy regulator 1
chr19_-_11618165 6.37 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr7_+_13357892 6.28 ENSMUST00000108525.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr15_-_101759212 6.27 ENSMUST00000023790.5
keratin 1
chr2_-_32278245 6.26 ENSMUST00000192241.2
lipocalin 2
chr19_-_34855278 6.18 ENSMUST00000112460.3
pantothenate kinase 1
chr9_+_7558449 6.07 ENSMUST00000018765.4
matrix metallopeptidase 8
chr13_-_53135064 6.01 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr10_+_97318223 5.92 ENSMUST00000163448.4
decorin
chr3_-_121608809 5.86 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr10_-_127358231 5.82 ENSMUST00000219239.2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_-_126873219 5.77 ENSMUST00000082428.6
selenophosphate synthetase 2
chr19_-_34855242 5.63 ENSMUST00000238065.2
pantothenate kinase 1
chr7_-_46392403 5.63 ENSMUST00000128088.4
serum amyloid A 1
chr9_-_71678814 5.52 ENSMUST00000122065.2
ENSMUST00000121322.8
ENSMUST00000072899.9
cingulin-like 1
chr1_-_106980033 5.51 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr6_+_141194886 5.51 ENSMUST00000043259.10
phosphodiesterase 3A, cGMP inhibited
chr17_+_29333116 5.44 ENSMUST00000233717.2
ENSMUST00000141239.2
RAB44, member RAS oncogene family
chr9_+_123902143 5.42 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr7_+_78563150 5.41 ENSMUST00000118867.8
interferon-stimulated protein
chr19_+_6451667 5.39 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr3_-_92528480 5.37 ENSMUST00000170676.3
late cornified envelope 6A
chr11_-_115968745 5.33 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr3_-_121608859 5.29 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr11_+_115353290 5.22 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr6_-_11907392 5.20 ENSMUST00000204084.3
ENSMUST00000031637.8
ENSMUST00000204978.3
ENSMUST00000204714.2
Ndufa4, mitochondrial complex associated
chr13_+_51254852 5.11 ENSMUST00000095797.6
spindlin 1
chr18_-_43925932 5.10 ENSMUST00000237926.2
ENSMUST00000096570.4
predicted gene 94
chr6_-_123266820 5.09 ENSMUST00000032239.11
ENSMUST00000177367.8
C-type lectin domain family 4, member e
chr4_+_114914607 5.03 ENSMUST00000136946.8
T cell acute lymphocytic leukemia 1
chr19_+_34268053 4.97 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chr18_+_4994600 4.97 ENSMUST00000140448.8
supervillin
chr6_+_40605758 4.91 ENSMUST00000202636.4
ENSMUST00000201148.4
ENSMUST00000071535.10
maltase-glucoamylase
chr13_-_61084358 4.84 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr10_+_102348076 4.70 ENSMUST00000219445.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chrX_-_137985979 4.67 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_+_97697128 4.67 ENSMUST00000138919.2
LIM and SH3 protein 1
chr13_+_31809774 4.65 ENSMUST00000042054.3
forkhead box F2
chr15_+_25940781 4.64 ENSMUST00000227275.2
reticulophagy regulator 1
chr8_+_95113066 4.64 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_+_35863025 4.61 ENSMUST00000044804.8
corneodesmosin
chr15_+_59520199 4.56 ENSMUST00000067543.8
tribbles pseudokinase 1
chr17_+_29077385 4.47 ENSMUST00000056866.8
patatin-like phospholipase domain containing 1
chr1_+_40123858 4.45 ENSMUST00000027243.13
interleukin 1 receptor, type II
chr4_+_155646807 4.43 ENSMUST00000030939.14
NAD kinase
chr16_+_42727926 4.40 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr19_+_34268071 4.39 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr11_-_33153587 4.34 ENSMUST00000037746.8
T cell leukemia, homeobox 3
chr18_-_52662917 4.34 ENSMUST00000171470.8
lysyl oxidase
chr14_+_66208253 4.30 ENSMUST00000138191.8
clusterin
chr11_-_115968576 4.29 ENSMUST00000106450.8
unc-13 homolog D
chr18_+_44237577 4.27 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr13_+_16186410 4.25 ENSMUST00000042603.14
inhibin beta-A
chr1_-_107088844 4.24 ENSMUST00000086694.11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
chr7_+_30475819 4.20 ENSMUST00000041703.10
dermokine
chr2_+_155593030 4.17 ENSMUST00000029140.12
ENSMUST00000132608.2
protein C receptor, endothelial
chr3_+_60436163 4.12 ENSMUST00000194201.6
ENSMUST00000193517.6
muscleblind like splicing factor 1
chr15_+_25940931 4.10 ENSMUST00000110438.3
reticulophagy regulator 1
chr19_+_12438125 4.08 ENSMUST00000081035.9
macrophage expressed gene 1
chrX_-_166047289 4.04 ENSMUST00000133722.2
toll-like receptor 8
chr15_+_59520493 3.99 ENSMUST00000118228.2
tribbles pseudokinase 1
chr2_-_118378020 3.97 ENSMUST00000110859.3
BCL2 modifying factor
chr11_-_83540175 3.87 ENSMUST00000001008.6
chemokine (C-C motif) ligand 3
chr10_+_79722081 3.74 ENSMUST00000046091.7
elastase, neutrophil expressed
chr2_+_117942357 3.73 ENSMUST00000039559.9
thrombospondin 1
chr11_-_115968373 3.67 ENSMUST00000174822.8
unc-13 homolog D
chr12_-_101784727 3.67 ENSMUST00000222587.2
fibulin 5
chr11_-_100139728 3.65 ENSMUST00000007280.9
keratin 16
chr6_-_129428746 3.64 ENSMUST00000204012.2
ENSMUST00000037481.10
C-type lectin domain family 1, member a
chr17_-_29226965 3.58 ENSMUST00000009138.13
ENSMUST00000119274.3
serine/threonine kinase 38
chr6_-_129428869 3.55 ENSMUST00000203162.3
C-type lectin domain family 1, member a
chr9_-_55190902 3.50 ENSMUST00000164721.8
neuregulin 4
chr17_-_57501170 3.48 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr18_-_52662728 3.45 ENSMUST00000025409.9
lysyl oxidase
chr13_-_40887444 3.43 ENSMUST00000224665.2
transcription factor AP-2, alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
26.1 78.2 GO:0009087 methionine catabolic process(GO:0009087)
11.9 59.4 GO:0048807 female genitalia morphogenesis(GO:0048807)
8.5 42.7 GO:0006548 histidine catabolic process(GO:0006548)
7.7 23.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
7.0 28.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
6.0 24.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
5.9 17.8 GO:0030573 bile acid catabolic process(GO:0030573)
5.6 16.9 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
5.1 41.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
4.9 14.6 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
4.6 18.4 GO:1903575 cornified envelope assembly(GO:1903575)
4.5 35.9 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
4.4 26.5 GO:0072592 oxygen metabolic process(GO:0072592)
4.3 38.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
4.1 12.4 GO:0033189 response to vitamin A(GO:0033189)
4.1 24.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651) positive regulation of phospholipase A2 activity(GO:0032430)
4.1 12.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
3.9 19.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.7 3.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
3.6 10.9 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
3.4 23.8 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
3.3 29.7 GO:0006572 tyrosine catabolic process(GO:0006572)
3.3 9.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
3.2 25.9 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.1 9.4 GO:0031104 dendrite regeneration(GO:0031104)
3.1 21.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
3.1 9.2 GO:0010040 response to iron(II) ion(GO:0010040)
3.0 35.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
2.9 8.8 GO:0070839 divalent metal ion export(GO:0070839)
2.9 8.7 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
2.9 8.6 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.8 11.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
2.8 33.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
2.7 13.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
2.7 8.2 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
2.7 27.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.7 24.2 GO:0061709 reticulophagy(GO:0061709)
2.4 31.8 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
2.4 24.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
2.4 7.1 GO:0015881 creatine transport(GO:0015881)
2.3 9.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
2.3 9.2 GO:0051673 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
2.2 9.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
2.2 8.9 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
2.2 29.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
2.2 6.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
2.2 11.0 GO:0009115 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
1.9 11.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.8 98.5 GO:0006953 acute-phase response(GO:0006953)
1.8 10.7 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
1.7 10.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.7 5.0 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.7 13.3 GO:0002432 granuloma formation(GO:0002432)
1.6 8.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.6 6.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.6 8.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.5 53.8 GO:0006825 copper ion transport(GO:0006825)
1.4 14.3 GO:0048251 elastic fiber assembly(GO:0048251)
1.4 78.1 GO:0050819 negative regulation of coagulation(GO:0050819)
1.3 41.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.3 4.0 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
1.3 7.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.3 13.8 GO:0044539 long-chain fatty acid import(GO:0044539)
1.2 14.5 GO:0002227 innate immune response in mucosa(GO:0002227)
1.2 3.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.1 4.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.9 37.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.9 5.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.9 2.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.8 5.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 5.8 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.8 3.2 GO:0042851 L-alanine metabolic process(GO:0042851)
0.8 7.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.8 4.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.7 11.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.7 2.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.7 5.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.7 3.4 GO:0003409 optic cup structural organization(GO:0003409)
0.7 2.0 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.7 13.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.6 2.6 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 5.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.6 13.7 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.5 8.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.5 3.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.5 8.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.5 35.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.5 12.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.5 10.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.5 4.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.5 1.5 GO:0009397 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.5 72.6 GO:0055088 lipid homeostasis(GO:0055088)
0.5 8.8 GO:0003334 keratinocyte development(GO:0003334)
0.4 44.0 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.4 1.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 2.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 5.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 1.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 3.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 4.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 3.6 GO:0051546 keratinocyte migration(GO:0051546)
0.3 0.9 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.3 4.6 GO:0043589 skin morphogenesis(GO:0043589)
0.3 2.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 3.9 GO:0043615 astrocyte cell migration(GO:0043615)
0.2 1.7 GO:0007527 adult somatic muscle development(GO:0007527)
0.2 5.6 GO:0030574 collagen catabolic process(GO:0030574)
0.2 3.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 9.2 GO:0030225 macrophage differentiation(GO:0030225)
0.2 2.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 4.6 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.2 4.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.2 7.4 GO:0030199 collagen fibril organization(GO:0030199)
0.2 5.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 3.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.2 3.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 34.6 GO:0007596 blood coagulation(GO:0007596) coagulation(GO:0050817)
0.2 5.1 GO:0009303 rRNA transcription(GO:0009303)
0.2 6.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 1.1 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 2.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 5.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 1.1 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 7.8 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 4.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 23.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 2.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.1 4.0 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 14.0 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 10.0 GO:0008202 steroid metabolic process(GO:0008202)
0.0 2.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 5.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 31.8 GO:0034359 mature chylomicron(GO:0034359)
8.2 24.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
7.2 64.8 GO:0005577 fibrinogen complex(GO:0005577)
3.6 14.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
3.3 35.9 GO:0097433 dense body(GO:0097433)
2.1 35.9 GO:0043203 axon hillock(GO:0043203)
1.9 29.9 GO:0044754 autolysosome(GO:0044754)
1.8 8.8 GO:0030312 external encapsulating structure(GO:0030312)
1.7 5.0 GO:0033193 Lsd1/2 complex(GO:0033193)
1.6 6.5 GO:0071953 elastic fiber(GO:0071953)
1.5 7.7 GO:0005914 spot adherens junction(GO:0005914)
1.5 9.2 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.4 4.3 GO:0043512 inhibin A complex(GO:0043512)
1.3 13.3 GO:0033093 Weibel-Palade body(GO:0033093)
1.2 12.3 GO:0070552 BRISC complex(GO:0070552)
1.2 48.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.2 4.6 GO:1990037 Lewy body core(GO:1990037)
1.0 9.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
1.0 10.9 GO:0070578 RISC-loading complex(GO:0070578)
1.0 7.8 GO:0030478 actin cap(GO:0030478)
0.9 10.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.8 204.1 GO:0072562 blood microparticle(GO:0072562)
0.7 8.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.7 14.5 GO:0042581 specific granule(GO:0042581)
0.5 74.3 GO:0016363 nuclear matrix(GO:0016363)
0.5 51.9 GO:0005811 lipid particle(GO:0005811)
0.5 12.9 GO:0005685 U1 snRNP(GO:0005685)
0.5 19.5 GO:0045095 keratin filament(GO:0045095)
0.4 1.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 11.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 22.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 2.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 3.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 5.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 5.9 GO:0098644 complex of collagen trimers(GO:0098644)
0.3 4.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 17.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 2.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 17.6 GO:0005882 intermediate filament(GO:0005882)
0.2 406.3 GO:0005615 extracellular space(GO:0005615)
0.2 11.8 GO:0030118 clathrin coat(GO:0030118)
0.2 2.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 13.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 5.0 GO:0043034 costamere(GO:0043034)
0.1 7.8 GO:0015030 Cajal body(GO:0015030)
0.1 13.8 GO:0005901 caveola(GO:0005901)
0.1 41.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 6.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 14.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 11.5 GO:0043195 terminal bouton(GO:0043195)
0.1 1.7 GO:0070938 contractile ring(GO:0070938)
0.1 4.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 7.6 GO:0016605 PML body(GO:0016605)
0.1 7.0 GO:0016459 myosin complex(GO:0016459)
0.1 15.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 7.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 8.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 6.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 10.9 GO:0005925 focal adhesion(GO:0005925)
0.0 1.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 33.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 36.1 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.8 59.4 GO:0034632 retinol transporter activity(GO:0034632)
19.6 78.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
9.1 27.4 GO:0042602 riboflavin reductase (NADPH) activity(GO:0042602)
7.2 21.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
6.1 42.7 GO:0016841 ammonia-lyase activity(GO:0016841)
6.0 23.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
5.2 41.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
5.1 35.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
5.0 30.2 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
4.9 14.6 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
4.8 24.2 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
4.6 13.9 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
4.6 13.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
4.1 12.3 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
3.9 11.6 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
3.8 15.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
3.6 17.8 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
3.4 40.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
2.9 8.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
2.8 13.8 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
2.6 12.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.4 31.8 GO:0035473 lipase binding(GO:0035473)
2.4 7.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
2.3 9.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
2.3 13.7 GO:0008384 IkappaB kinase activity(GO:0008384)
2.2 8.9 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
2.2 26.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.2 24.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.2 11.0 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
2.0 11.8 GO:0004594 pantothenate kinase activity(GO:0004594)
1.9 5.8 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.7 11.9 GO:0071723 lipopeptide binding(GO:0071723)
1.7 13.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.6 7.8 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 7.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.2 11.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.1 9.2 GO:0004630 phospholipase D activity(GO:0004630)
1.1 4.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.1 8.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.0 6.3 GO:0030280 structural constituent of epidermis(GO:0030280)
1.0 30.2 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
1.0 10.9 GO:0019957 C-C chemokine binding(GO:0019957)
1.0 111.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.9 3.7 GO:0070052 collagen V binding(GO:0070052)
0.9 2.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.9 13.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.8 29.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.8 16.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.8 4.9 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.7 2.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.7 3.4 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.6 101.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 3.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.6 3.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.6 18.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 6.5 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.5 4.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 8.8 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.5 5.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.5 1.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.5 19.3 GO:0042056 chemoattractant activity(GO:0042056)
0.4 5.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 11.3 GO:0051787 misfolded protein binding(GO:0051787)
0.4 24.7 GO:0005507 copper ion binding(GO:0005507)
0.4 82.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 35.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.3 13.4 GO:0043236 laminin binding(GO:0043236)
0.3 0.9 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.3 19.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 2.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 2.5 GO:0008061 chitin binding(GO:0008061)
0.2 44.2 GO:0005506 iron ion binding(GO:0005506)
0.2 4.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 70.2 GO:0030246 carbohydrate binding(GO:0030246)
0.2 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 10.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 6.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 3.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 38.3 GO:0030674 protein binding, bridging(GO:0030674)
0.2 5.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.5 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.2 1.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 4.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 8.2 GO:0050699 WW domain binding(GO:0050699)
0.1 26.4 GO:0016853 isomerase activity(GO:0016853)
0.1 2.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 5.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.2 GO:0031005 filamin binding(GO:0031005)
0.1 3.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 11.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 5.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 4.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 10.4 GO:0005179 hormone activity(GO:0005179)
0.1 5.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.0 GO:0070888 E-box binding(GO:0070888)
0.1 5.1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 7.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 6.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 8.1 GO:0005178 integrin binding(GO:0005178)
0.0 11.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 9.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 26.1 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 9.8 GO:0003924 GTPase activity(GO:0003924)
0.0 5.5 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 3.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.6 GO:0044325 ion channel binding(GO:0044325)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 8.4 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 100.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.6 14.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.2 70.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.6 9.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 50.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 18.2 PID IL1 PATHWAY IL1-mediated signaling events
0.4 11.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 105.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 23.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.4 23.2 PID BMP PATHWAY BMP receptor signaling
0.3 6.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 9.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 19.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 52.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 5.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 11.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 6.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 4.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 5.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 23.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 41.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
3.6 61.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
3.0 61.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
2.3 78.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.7 24.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.7 41.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.4 26.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.2 4.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.1 48.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.1 31.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.0 19.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.9 8.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.8 11.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8 27.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.8 14.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.7 11.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.6 8.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 9.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.5 5.6 REACTOME OPSINS Genes involved in Opsins
0.5 14.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 10.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.5 11.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 22.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.4 5.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 24.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.4 90.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.4 16.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 7.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 9.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 11.7 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.3 1.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 7.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 7.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 7.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 12.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 15.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 7.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 8.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 22.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 9.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 8.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 5.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport