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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap
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Results for Cebpe
Z-value: 2.99
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Transcription factors associated with Cebpe
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpe | mm39_v1_chr14_-_54949596_54949631 | 0.32 | 6.4e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Cebpe
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_87288177 Show fit | 50.25 |
ENSMUST00000067790.7
|
UDP glucuronosyltransferase 2 family, polypeptide B5 |
|
| chr5_-_87240405 Show fit | 45.50 |
ENSMUST00000132667.2
ENSMUST00000145617.8 ENSMUST00000094649.11 |
UDP glucuronosyltransferase 2 family, polypeptide B36 |
|
| chr14_+_40827317 Show fit | 40.52 |
ENSMUST00000047286.7
|
methionine adenosyltransferase I, alpha |
|
| chr3_+_59939175 Show fit | 35.42 |
ENSMUST00000029325.5
|
arylacetamide deacetylase |
|
| chr14_+_40826970 Show fit | 35.06 |
ENSMUST00000225720.2
|
methionine adenosyltransferase I, alpha |
|
| chr5_-_87485023 Show fit | 34.92 |
ENSMUST00000031195.3
|
UDP glucuronosyltransferase 2 family, polypeptide A3 |
|
| chr14_+_40827108 Show fit | 34.07 |
ENSMUST00000224514.2
|
methionine adenosyltransferase I, alpha |
|
| chr12_+_8062331 Show fit | 30.30 |
ENSMUST00000171239.2
|
apolipoprotein B |
|
| chr6_-_128503666 Show fit | 29.10 |
ENSMUST00000143664.2
ENSMUST00000112132.8 |
PZP, alpha-2-macroglobulin like |
|
| chr19_-_39729431 Show fit | 27.22 |
ENSMUST00000099472.4
|
cytochrome P450, family 2, subfamily c, polypeptide 68 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.5 | 181.7 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 36.5 | 109.6 | GO:0009087 | methionine catabolic process(GO:0009087) |
| 4.1 | 102.4 | GO:0080184 | response to phenylpropanoid(GO:0080184) |
| 4.9 | 69.0 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 4.2 | 62.4 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 4.5 | 53.7 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.0 | 53.4 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 3.9 | 50.3 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 3.0 | 44.4 | GO:0015747 | urate transport(GO:0015747) |
| 0.5 | 43.6 | GO:0006637 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 204.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 172.2 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.1 | 167.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.2 | 112.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.7 | 107.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.3 | 60.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 54.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 15.9 | 47.7 | GO:0034359 | mature chylomicron(GO:0034359) |
| 0.8 | 32.0 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 3.5 | 31.4 | GO:0005579 | membrane attack complex(GO:0005579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.8 | 278.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 5.3 | 196.7 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
| 27.4 | 109.6 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.0 | 57.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 3.7 | 47.7 | GO:0035473 | lipase binding(GO:0035473) |
| 2.8 | 42.7 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 2.5 | 42.1 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 6.8 | 40.7 | GO:0030294 | receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294) |
| 1.7 | 35.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 11.3 | 34.0 | GO:0005009 | insulin-activated receptor activity(GO:0005009) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 56.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.7 | 50.4 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.4 | 42.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.6 | 39.0 | PID BMP PATHWAY | BMP receptor signaling |
| 1.0 | 22.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.8 | 21.2 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 17.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.3 | 17.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 16.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.2 | 15.8 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 109.6 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.3 | 56.1 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 3.7 | 51.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 1.6 | 47.7 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 2.6 | 43.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 3.5 | 38.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.8 | 34.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 2.3 | 32.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.7 | 30.0 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 1.5 | 29.0 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |