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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Cpeb1

Z-value: 2.17

Motif logo

Transcription factors associated with Cpeb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025586.18 Cpeb1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cpeb1mm39_v1_chr7_-_81104423_811045120.514.6e-06Click!

Activity profile of Cpeb1 motif

Sorted Z-values of Cpeb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Cpeb1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_+_55825033 13.14 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr3_+_106020545 13.13 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chrX_+_55824797 12.70 ENSMUST00000114773.10
four and a half LIM domains 1
chr8_+_94537910 12.35 ENSMUST00000138659.9
guanine nucleotide binding protein, alpha O
chr3_-_92616380 11.61 ENSMUST00000090867.2
late cornified envelope 1E
chr3_+_92899521 11.35 ENSMUST00000090863.5
late cornified envelope 3F
chr3_-_92922976 11.21 ENSMUST00000107301.2
ENSMUST00000029521.5
cysteine-rich C-terminal 1
chr3_+_68491487 11.10 ENSMUST00000182997.3
schwannomin interacting protein 1
chr18_-_15284476 11.03 ENSMUST00000025992.7
potassium channel tetramerisation domain containing 1
chr3_-_92564232 10.94 ENSMUST00000029531.4
late cornified envelope 1B
chr7_+_30475819 10.60 ENSMUST00000041703.10
dermokine
chr14_-_57371041 10.39 ENSMUST00000039380.9
gap junction protein, beta 6
chr2_+_109522781 10.15 ENSMUST00000111050.10
brain derived neurotrophic factor
chr3_+_87855973 10.10 ENSMUST00000005019.6
cellular retinoic acid binding protein II
chr18_+_69726431 9.90 ENSMUST00000201091.4
ENSMUST00000201037.4
ENSMUST00000114977.5
transcription factor 4
chr3_-_92833537 9.87 ENSMUST00000067318.6
late cornified envelope 3A
chr3_-_92715195 9.77 ENSMUST00000179917.2
late cornified envelope 1K
chr3_-_92594516 9.46 ENSMUST00000029524.4
late cornified envelope 1D
chr3_-_92577621 9.45 ENSMUST00000029530.6
late cornified envelope 1A2
chr1_-_171023798 9.42 ENSMUST00000111332.2
Purkinje cell protein 4-like 1
chr19_+_39049442 9.35 ENSMUST00000087236.5
cytochrome P450, family 2, subfamily c, polypeptide 65
chr5_+_76988444 9.32 ENSMUST00000120639.9
ENSMUST00000163347.8
ENSMUST00000121851.2
capping protein inhibiting regulator of actin
chr3_+_92586546 9.23 ENSMUST00000047055.4
late cornified envelope 1C
chr3_-_92777521 9.14 ENSMUST00000163439.3
RIKEN cDNA 2310050C09 gene
chr1_-_79838897 8.97 ENSMUST00000190724.2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr11_-_42073737 8.96 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr3_-_92686198 8.94 ENSMUST00000090866.2
late cornified envelope 1I
chr10_-_127025851 8.91 ENSMUST00000222006.2
ENSMUST00000019611.15
ENSMUST00000219245.2
Rho guanine nucleotide exchange factor (GEF) 25
chr3_-_92366022 8.64 ENSMUST00000058142.4
small proline-rich protein 3
chr19_+_17114108 8.46 ENSMUST00000223920.2
ENSMUST00000225351.2
prune homolog 2
chr3_-_92659644 8.46 ENSMUST00000029527.6
late cornified envelope 1G
chr5_+_107645626 8.31 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr3_-_92627651 8.29 ENSMUST00000047153.4
late cornified envelope 1F
chr11_-_79394904 8.24 ENSMUST00000164465.3
oligodendrocyte myelin glycoprotein
chr16_+_25620652 8.15 ENSMUST00000115304.8
ENSMUST00000115305.2
ENSMUST00000040231.13
ENSMUST00000115306.8
transformation related protein 63
chr3_+_92851790 8.11 ENSMUST00000055375.6
late cornified envelope 3C
chr18_+_20443795 8.07 ENSMUST00000077146.4
desmoglein 1 alpha
chr1_-_169575203 8.02 ENSMUST00000027991.12
ENSMUST00000111357.2
regulator of G-protein signaling 4
chr5_+_149335214 7.64 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr3_+_93227047 7.61 ENSMUST00000090856.10
ENSMUST00000093774.4
hornerin
chr3_-_63758672 7.59 ENSMUST00000162269.9
ENSMUST00000159676.9
ENSMUST00000175947.8
phospholipase C, eta 1
chr10_+_29087658 7.58 ENSMUST00000213489.2
RIKEN cDNA 9330159F19 gene
chr3_-_92697821 7.43 ENSMUST00000186525.2
late cornified envelope 1J
chr10_+_5589210 7.34 ENSMUST00000019906.6
vasoactive intestinal polypeptide
chr10_+_29087602 7.19 ENSMUST00000092627.6
RIKEN cDNA 9330159F19 gene
chr11_+_67477347 7.19 ENSMUST00000108682.9
growth arrest specific 7
chr3_-_92672367 7.06 ENSMUST00000051521.5
late cornified envelope 1H
chr2_-_110781268 6.95 ENSMUST00000099623.10
anoctamin 3
chr19_-_5399368 6.94 ENSMUST00000238111.2
cystatin E/M
chr3_+_93184854 6.89 ENSMUST00000180308.3
filaggrin
chr11_+_67477501 6.87 ENSMUST00000108680.2
growth arrest specific 7
chrX_-_94209913 6.86 ENSMUST00000113873.9
ENSMUST00000113876.9
ENSMUST00000199920.5
ENSMUST00000113885.8
ENSMUST00000113883.8
ENSMUST00000196012.2
ENSMUST00000182001.8
ENSMUST00000113878.8
ENSMUST00000113882.8
ENSMUST00000182562.2
CDC42 guanine nucleotide exchange factor (GEF) 9
chr11_-_42072990 6.84 ENSMUST00000205546.2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_-_136852792 6.72 ENSMUST00000032342.3
matrix Gla protein
chr10_+_70276604 6.72 ENSMUST00000173042.9
ENSMUST00000062883.7
family with sequence similarity 13, member C
chr11_+_104467791 6.70 ENSMUST00000106957.8
myosin, light polypeptide 4
chr15_-_101862711 6.66 ENSMUST00000164932.3
keratin 78
chr11_-_118246566 6.66 ENSMUST00000155707.3
tissue inhibitor of metalloproteinase 2
chr19_+_29902506 6.46 ENSMUST00000120388.9
ENSMUST00000144528.8
ENSMUST00000177518.8
interleukin 33
chr11_+_42312150 6.36 ENSMUST00000192403.2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr8_+_40807344 6.21 ENSMUST00000136835.2
mitochondrial calcium uptake family, member 3
chr19_+_34078333 6.13 ENSMUST00000025685.8
lipase, family member M
chrX_+_133618693 6.07 ENSMUST00000113201.8
ENSMUST00000051256.10
ENSMUST00000113199.8
ENSMUST00000035748.14
ENSMUST00000113198.8
ENSMUST00000113197.2
armadillo repeat containing, X-linked 1
chr3_+_92874366 6.05 ENSMUST00000098886.5
late cornified envelope 3E
chr2_+_83642910 5.86 ENSMUST00000051454.4
family with sequence similarity 171, member B
chr11_+_100902572 5.84 ENSMUST00000092663.4
ATPase, H+ transporting, lysosomal V0 subunit A1
chr1_-_22031718 5.76 ENSMUST00000029667.13
ENSMUST00000173058.8
ENSMUST00000173404.2
potassium voltage-gated channel, subfamily Q, member 5
chr3_+_92864693 5.75 ENSMUST00000059053.11
late cornified envelope 3D
chr8_+_94537460 5.73 ENSMUST00000034198.15
ENSMUST00000125716.8
guanine nucleotide binding protein, alpha O
chr11_+_104468107 5.72 ENSMUST00000106956.10
myosin, light polypeptide 4
chr18_+_69726654 5.60 ENSMUST00000200921.4
transcription factor 4
chr3_+_113824181 5.52 ENSMUST00000123619.8
ENSMUST00000092155.12
collagen, type XI, alpha 1
chr12_-_90705212 5.52 ENSMUST00000082432.6
deiodinase, iodothyronine, type II
chr3_+_102641822 5.43 ENSMUST00000029451.12
tetraspanin 2
chr14_-_28691423 5.42 ENSMUST00000225985.2
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr18_+_69652837 5.41 ENSMUST00000201410.4
ENSMUST00000202937.4
transcription factor 4
chr3_-_59170245 5.39 ENSMUST00000050360.14
ENSMUST00000199609.2
purinergic receptor P2Y, G-protein coupled 12
chr16_+_96001865 5.38 ENSMUST00000171181.9
ENSMUST00000233818.2
ENSMUST00000233945.2
ENSMUST00000166952.8
SH3-binding domain glutamic acid-rich protein
chr18_+_44237577 5.37 ENSMUST00000239465.2
serine peptidase inhibitor, Kazal type 12
chr11_-_42072920 5.36 ENSMUST00000207274.2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr13_+_93441447 5.31 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
homer scaffolding protein 1
chr3_-_92926364 5.30 ENSMUST00000193944.2
ENSMUST00000029520.9
late cornified envelope 1M
chr3_-_92393193 5.29 ENSMUST00000054599.8
small proline-rich protein 1A
chr3_-_106126794 5.24 ENSMUST00000082219.6
chitinase-like 4
chr17_+_72088281 5.24 ENSMUST00000229874.2
CAP-GLY domain containing linker protein family, member 4
chr13_-_78347876 5.23 ENSMUST00000091458.13
nuclear receptor subfamily 2, group F, member 1
chr10_-_49659355 5.21 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr18_+_44096300 5.20 ENSMUST00000069245.8
serine peptidase inhibitor, Kazal type 5
chr7_-_109380745 5.17 ENSMUST00000207400.2
ENSMUST00000033331.7
nuclear receptor interacting protein 3
chr11_-_118246332 5.16 ENSMUST00000017610.10
tissue inhibitor of metalloproteinase 2
chr13_+_83652352 5.14 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr3_+_92840279 5.11 ENSMUST00000046234.5
late cornified envelope 3B
chr10_+_45453907 5.09 ENSMUST00000037044.13
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr1_-_45542442 5.03 ENSMUST00000086430.5
collagen, type V, alpha 2
chr10_+_70276473 5.02 ENSMUST00000105436.9
family with sequence similarity 13, member C
chr8_+_94879235 4.86 ENSMUST00000034211.10
ENSMUST00000211930.2
ENSMUST00000211915.2
metallothionein 3
chr18_-_25886750 4.81 ENSMUST00000224553.2
ENSMUST00000025117.14
CUGBP, Elav-like family member 4
chrX_+_140258381 4.81 ENSMUST00000112931.8
ENSMUST00000112930.8
collagen, type IV, alpha 5
chr2_-_165997551 4.80 ENSMUST00000109249.9
ENSMUST00000146497.9
sulfatase 2
chr2_+_51928017 4.80 ENSMUST00000065927.6
tumor necrosis factor alpha induced protein 6
chr11_-_81859241 4.79 ENSMUST00000066197.7
acid-sensing (proton-gated) ion channel 2
chr18_-_43032359 4.78 ENSMUST00000117687.8
protein phosphatase 2, regulatory subunit B, beta
chr2_+_14393127 4.78 ENSMUST00000114731.8
ENSMUST00000082290.8
solute carrier family 39 (zinc transporter), member 12
chr3_-_141637245 4.77 ENSMUST00000106232.8
bone morphogenetic protein receptor, type 1B
chr1_-_22551594 4.77 ENSMUST00000239255.2
regulating synaptic membrane exocytosis 1
chr1_-_168259465 4.75 ENSMUST00000176540.8
pre B cell leukemia homeobox 1
chr10_-_43050516 4.64 ENSMUST00000040275.9
sine oculis binding protein
chr12_+_38830081 4.56 ENSMUST00000095767.11
ets variant 1
chr3_+_109481223 4.52 ENSMUST00000106576.3
vav 3 oncogene
chr15_+_36179676 4.51 ENSMUST00000171205.3
sperm associated antigen 1
chr18_-_43032535 4.49 ENSMUST00000120632.2
protein phosphatase 2, regulatory subunit B, beta
chr16_+_56298228 4.42 ENSMUST00000231832.2
ENSMUST00000096013.11
ENSMUST00000048471.15
ENSMUST00000231870.2
ENSMUST00000171000.3
ENSMUST00000231781.2
ENSMUST00000096012.11
ABI family member 3 binding protein
chr6_-_7693110 4.41 ENSMUST00000126303.8
asparagine synthetase
chr2_+_65760477 4.33 ENSMUST00000176109.8
cysteine-serine-rich nuclear protein 3
chrX_+_158623460 4.31 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr5_+_92540444 4.31 ENSMUST00000126281.8
ADP-ribosyltransferase 3
chr11_-_42070517 4.27 ENSMUST00000206105.2
ENSMUST00000153147.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr1_-_168259839 4.21 ENSMUST00000188912.7
pre B cell leukemia homeobox 1
chr2_-_103133524 4.19 ENSMUST00000090475.10
ets homologous factor
chr1_+_106908709 4.18 ENSMUST00000027564.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr16_-_56652241 4.17 ENSMUST00000135672.2
transmembrane protein 45a
chr7_+_87233554 4.17 ENSMUST00000125009.9
glutamate receptor, metabotropic 5
chr10_+_115653152 4.17 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr2_-_52448552 4.17 ENSMUST00000102760.10
ENSMUST00000102761.9
calcium channel, voltage-dependent, beta 4 subunit
chr4_-_14621805 4.17 ENSMUST00000042221.14
solute carrier family 26, member 7
chr17_+_14087827 4.16 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr17_-_52133594 4.16 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr16_-_21814190 4.16 ENSMUST00000231766.2
ENSMUST00000074230.12
lipase, member H
chr3_+_67799510 4.14 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr1_+_179928709 4.13 ENSMUST00000133890.8
CDC42 binding protein kinase alpha
chr2_+_14393245 4.10 ENSMUST00000133258.2
solute carrier family 39 (zinc transporter), member 12
chr7_-_30750856 4.10 ENSMUST00000073892.6
FXYD domain-containing ion transport regulator 7
chr16_+_96001650 4.09 ENSMUST00000048770.16
SH3-binding domain glutamic acid-rich protein
chr5_-_73805063 4.09 ENSMUST00000081170.9
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr13_+_93441307 4.05 ENSMUST00000080127.12
homer scaffolding protein 1
chr3_+_96577447 4.05 ENSMUST00000048427.9
ankyrin repeat domain 35
chr13_-_78344492 4.04 ENSMUST00000125176.3
nuclear receptor subfamily 2, group F, member 1
chr6_-_112923715 4.04 ENSMUST00000113169.9
SLIT-ROBO Rho GTPase activating protein 3
chr13_-_113182891 4.03 ENSMUST00000231962.2
ENSMUST00000022282.6
glutathione peroxidase 8 (putative)
chr1_+_107289659 4.00 ENSMUST00000027566.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr2_+_16361582 3.99 ENSMUST00000114703.10
plexin domain containing 2
chr18_+_36431732 3.99 ENSMUST00000210490.3
IgA inducing protein
chr7_+_43339842 3.97 ENSMUST00000056329.7
kallikrein related-peptidase 14
chr11_-_100036792 3.96 ENSMUST00000007317.8
keratin 19
chr2_+_131751848 3.95 ENSMUST00000091288.13
ENSMUST00000124100.8
ENSMUST00000136783.2
prion protein
prion protein readthrough transcript
chr4_-_68872585 3.95 ENSMUST00000030036.6
bone morphogenic protein/retinoic acid inducible neural specific 1
chr18_-_12438695 3.93 ENSMUST00000122408.8
ENSMUST00000234183.2
ENSMUST00000142066.2
ENSMUST00000118525.9
ankyrin repeat domain 29
chr9_+_122752116 3.91 ENSMUST00000051667.14
zinc finger protein 105
chr18_+_69726055 3.91 ENSMUST00000114978.9
transcription factor 4
chr4_-_87951565 3.90 ENSMUST00000078090.12
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr5_+_13449276 3.90 ENSMUST00000030714.9
ENSMUST00000141968.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr13_+_83723743 3.83 ENSMUST00000198217.5
ENSMUST00000199210.5
myocyte enhancer factor 2C
chr4_-_154721288 3.79 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr10_-_63926044 3.79 ENSMUST00000105439.2
leucine rich repeat transmembrane neuronal 3
chr11_+_81992662 3.78 ENSMUST00000000194.4
chemokine (C-C motif) ligand 12
chr11_+_29413734 3.78 ENSMUST00000155854.8
coiled coil domain containing 88A
chr17_-_82045800 3.77 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_4122523 3.75 ENSMUST00000119661.8
ENSMUST00000129423.8
tweety family member 1
chr16_+_94225942 3.74 ENSMUST00000141176.2
tetratricopeptide repeat domain 3
chr3_-_26386609 3.70 ENSMUST00000193603.6
neuroligin 1
chr4_+_101365144 3.68 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr16_-_21814289 3.64 ENSMUST00000060673.8
lipase, member H
chr6_-_112924205 3.62 ENSMUST00000088373.11
SLIT-ROBO Rho GTPase activating protein 3
chr6_+_8520006 3.61 ENSMUST00000162567.8
ENSMUST00000161217.8
glucocorticoid induced transcript 1
chr2_-_103133503 3.59 ENSMUST00000111176.9
ets homologous factor
chr1_-_37535202 3.59 ENSMUST00000143636.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr18_+_20509771 3.59 ENSMUST00000076737.7
desmoglein 1 beta
chr19_+_8828132 3.57 ENSMUST00000235683.2
ENSMUST00000096257.3
LRRN4 C-terminal like
chr10_-_30647836 3.57 ENSMUST00000215926.2
ENSMUST00000213836.2
nuclear receptor coactivator 7
chr11_-_99134885 3.55 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr12_+_38833501 3.53 ENSMUST00000159334.8
ets variant 1
chrX_-_58211440 3.53 ENSMUST00000119306.2
fibroblast growth factor 13
chr13_+_42454922 3.50 ENSMUST00000021796.9
endothelin 1
chrX_+_136552469 3.50 ENSMUST00000075471.4
interleukin 1 receptor accessory protein-like 2
chr18_+_37858753 3.48 ENSMUST00000066149.9
protocadherin gamma subfamily A, 8
chr10_+_102376109 3.47 ENSMUST00000055355.6
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr19_+_39102342 3.45 ENSMUST00000087234.3
cytochrome P450, family 2, subfamily c, polypeptide 66
chr1_-_168259264 3.44 ENSMUST00000176790.8
pre B cell leukemia homeobox 1
chr8_-_34237752 3.39 ENSMUST00000179364.3
small integral membrane protein 18
chr1_+_12762501 3.37 ENSMUST00000177608.8
ENSMUST00000180062.8
sulfatase 1
chr10_-_30531832 3.37 ENSMUST00000217138.2
ENSMUST00000217644.2
ENSMUST00000216172.2
nuclear receptor coactivator 7
chrX_+_9751861 3.36 ENSMUST00000067529.9
ENSMUST00000086165.4
synaptotagmin-like 5
chr17_+_24026892 3.30 ENSMUST00000191385.3
serine/arginine repetitive matrix 2
chr7_+_142052569 3.28 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr9_-_37058590 3.28 ENSMUST00000080754.12
ENSMUST00000188057.7
ENSMUST00000039674.13
Pbx/knotted 1 homeobox 2
chr3_-_33039225 3.26 ENSMUST00000108221.2
peroxisomal biogenesis factor 5-like
chr7_+_4122555 3.25 ENSMUST00000079415.12
tweety family member 1
chr6_-_53797748 3.25 ENSMUST00000127748.5
TLR4 interactor with leucine-rich repeats
chr9_+_54606798 3.21 ENSMUST00000154690.8
DnaJ heat shock protein family (Hsp40) member A4
chr7_-_30750828 3.19 ENSMUST00000206341.2
FXYD domain-containing ion transport regulator 7
chr6_-_87958611 3.18 ENSMUST00000056403.7
H1.10 linker histone
chr6_-_138398376 3.17 ENSMUST00000163065.8
LIM domain only 3
chr12_-_36092475 3.17 ENSMUST00000020896.17
tetraspanin 13
chrX_+_13498321 3.16 ENSMUST00000041708.10
G protein-coupled receptor 34
chr4_-_91264670 3.12 ENSMUST00000107109.9
ENSMUST00000107111.9
ENSMUST00000107120.8
ELAV like RNA binding protein 1
chr5_+_92534738 3.11 ENSMUST00000128246.8
ADP-ribosyltransferase 3
chr15_+_16728842 3.11 ENSMUST00000228307.2
cadherin 9
chr1_-_157084252 3.11 ENSMUST00000134543.8
RAS protein activator like 2
chr14_-_24227857 3.10 ENSMUST00000042009.13
discs large MAGUK scaffold protein 5
chr18_+_37637317 3.10 ENSMUST00000052179.8
protocadherin beta 20

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
3.4 10.1 GO:0061193 taste bud development(GO:0061193)
3.0 9.0 GO:0061107 seminal vesicle development(GO:0061107)
2.7 8.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) cloacal septation(GO:0060197)
2.7 8.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.6 10.6 GO:1903575 cornified envelope assembly(GO:1903575)
2.5 178.1 GO:0018149 peptide cross-linking(GO:0018149)
2.2 19.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.9 11.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.9 5.6 GO:0070194 synaptonemal complex disassembly(GO:0070194)
1.8 5.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.7 10.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.7 5.1 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
1.6 4.9 GO:0097212 lysosomal membrane organization(GO:0097212)
1.6 18.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.4 31.8 GO:0071420 cellular response to histamine(GO:0071420)
1.4 5.5 GO:0035989 tendon development(GO:0035989)
1.4 5.5 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
1.3 3.9 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
1.3 5.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.2 3.7 GO:0098942 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
1.2 3.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.1 12.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.1 5.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.1 4.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.0 5.2 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
1.0 4.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.0 6.9 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.0 4.8 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.0 4.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.9 6.5 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.9 2.8 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.9 11.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.9 2.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.9 1.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.9 6.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.8 2.4 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.8 4.8 GO:0050915 sensory perception of sour taste(GO:0050915)
0.8 21.4 GO:0042118 endothelial cell activation(GO:0042118)
0.8 2.3 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.8 3.1 GO:0045186 zonula adherens assembly(GO:0045186)
0.7 11.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.7 3.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.7 2.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.7 4.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.7 5.4 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.7 4.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.7 12.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.6 10.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 3.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.6 2.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.6 0.6 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.6 8.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.6 1.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.6 1.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.5 1.6 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.5 25.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.5 1.0 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.5 3.9 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5 8.2 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.5 9.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 8.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.5 2.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.5 2.7 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.4 3.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4 1.3 GO:0098749 cerebellar neuron development(GO:0098749)
0.4 2.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.4 15.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.4 2.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.4 3.8 GO:0071313 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.4 6.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 11.1 GO:0001553 luteinization(GO:0001553)
0.4 3.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 1.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 1.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.4 1.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.4 2.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.4 1.5 GO:0035566 regulation of metanephros size(GO:0035566)
0.4 6.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 9.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 4.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 2.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.4 3.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3 3.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.3 6.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 1.4 GO:0006069 ethanol oxidation(GO:0006069)
0.3 1.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.3 5.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 2.6 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 6.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.3 7.6 GO:0031424 keratinization(GO:0031424)
0.3 3.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 2.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 7.7 GO:0045109 intermediate filament organization(GO:0045109)
0.3 2.5 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.3 12.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.3 4.0 GO:0007320 insemination(GO:0007320)
0.3 1.2 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.3 4.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 3.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 0.9 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.3 1.7 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.3 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 4.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 2.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.7 GO:0031000 response to caffeine(GO:0031000)
0.3 6.1 GO:0007614 short-term memory(GO:0007614)
0.3 16.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.3 1.3 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.3 1.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.3 2.3 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2 4.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 5.5 GO:0008272 sulfate transport(GO:0008272)
0.2 0.5 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2 1.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 6.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 0.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0060434 regulation of tolerance induction to self antigen(GO:0002649) bronchus morphogenesis(GO:0060434)
0.2 2.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 4.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 2.0 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.2 4.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 4.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 1.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 1.6 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 2.2 GO:0015705 iodide transport(GO:0015705)
0.2 1.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 2.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.2 1.0 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 2.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.2 5.8 GO:0007035 vacuolar acidification(GO:0007035)
0.2 1.3 GO:0060023 soft palate development(GO:0060023)
0.2 13.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 2.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 7.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.0 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 0.2 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.2 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 7.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 9.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 0.9 GO:0072553 terminal button organization(GO:0072553)
0.1 1.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 2.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 1.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 4.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.0 GO:0006527 arginine catabolic process(GO:0006527)
0.1 2.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.9 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1 1.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 3.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 4.0 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.3 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.9 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 8.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.0 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 14.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 3.6 GO:0090102 cochlea development(GO:0090102)
0.1 0.6 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 3.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.5 GO:0009624 response to nematode(GO:0009624)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.5 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 1.7 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 6.9 GO:0043113 receptor clustering(GO:0043113)
0.1 1.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 3.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 4.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 2.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 7.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.2 GO:0006027 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027) chondroitin sulfate metabolic process(GO:0030204)
0.1 1.1 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.7 GO:0006817 phosphate ion transport(GO:0006817)
0.1 3.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 3.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 1.3 GO:0072606 interleukin-8 secretion(GO:0072606)
0.1 1.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 2.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 11.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.1 8.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 3.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 3.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 6.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 4.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.8 GO:0001967 suckling behavior(GO:0001967)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 5.5 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 3.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.9 GO:0007099 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.9 GO:0031295 T cell costimulation(GO:0031295)
0.0 1.9 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 3.8 GO:0007416 synapse assembly(GO:0007416)
0.0 2.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 4.3 GO:0007338 single fertilization(GO:0007338)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 6.0 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.0 4.2 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 2.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 1.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.0 2.7 GO:0016197 endosomal transport(GO:0016197)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.9 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 200.2 GO:0001533 cornified envelope(GO:0001533)
1.7 5.0 GO:0005588 collagen type V trimer(GO:0005588)
1.1 31.8 GO:1902711 GABA-A receptor complex(GO:1902711)
1.0 5.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.8 4.8 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.8 5.4 GO:0005955 calcineurin complex(GO:0005955)
0.7 5.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 9.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.7 4.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7 5.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.6 5.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 3.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 10.1 GO:0030061 mitochondrial crista(GO:0030061)
0.5 3.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 9.1 GO:0005861 troponin complex(GO:0005861)
0.5 1.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 5.6 GO:0072687 meiotic spindle(GO:0072687)
0.5 4.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 4.0 GO:1990357 terminal web(GO:1990357)
0.4 10.7 GO:0032433 filopodium tip(GO:0032433)
0.4 3.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 5.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.4 13.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 10.4 GO:0005922 connexon complex(GO:0005922)
0.3 2.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 1.0 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.3 10.4 GO:0030057 desmosome(GO:0030057)
0.3 5.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 4.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 18.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 3.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 14.3 GO:0043034 costamere(GO:0043034)
0.2 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0071942 XPC complex(GO:0071942)
0.2 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.2 1.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 14.4 GO:0031672 A band(GO:0031672)
0.2 3.0 GO:0000243 commitment complex(GO:0000243)
0.2 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.9 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 2.3 GO:0005883 neurofilament(GO:0005883)
0.2 2.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.2 GO:0097449 astrocyte projection(GO:0097449)
0.2 1.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 3.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 10.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.0 GO:0033391 chromatoid body(GO:0033391)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 14.4 GO:0005884 actin filament(GO:0005884)
0.1 30.0 GO:0030016 myofibril(GO:0030016)
0.1 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.0 GO:0032982 myosin filament(GO:0032982)
0.1 10.6 GO:0042641 actomyosin(GO:0042641)
0.1 5.6 GO:0014704 intercalated disc(GO:0014704)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 18.2 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 20.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 10.7 GO:0005604 basement membrane(GO:0005604)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2 complex(GO:0005850) eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 14.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.6 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.8 GO:0016235 aggresome(GO:0016235)
0.1 5.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 3.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 6.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 15.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 7.2 GO:0043195 terminal bouton(GO:0043195)
0.0 3.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 18.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 6.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 3.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.0 GO:0005814 centriole(GO:0005814)
0.0 2.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.7 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 3.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.0 GO:0005938 cell cortex(GO:0005938)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 4.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 7.3 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 3.5 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0044297 cell body(GO:0044297)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 12.9 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
3.2 25.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.6 12.8 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
2.3 18.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
2.2 19.9 GO:0004568 chitinase activity(GO:0004568)
2.2 12.9 GO:0030280 structural constituent of epidermis(GO:0030280)
1.8 29.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.6 11.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.5 5.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.4 4.2 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
1.4 5.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.3 3.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.1 4.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
1.0 13.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.9 5.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.9 5.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 3.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.9 3.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.9 5.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.9 7.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 3.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 3.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.7 2.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.7 17.9 GO:0003680 AT DNA binding(GO:0003680)
0.6 5.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.6 3.9 GO:1990254 keratin filament binding(GO:1990254)
0.6 11.5 GO:0019841 retinol binding(GO:0019841)
0.6 1.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.6 6.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.6 2.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.6 5.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 4.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.5 3.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.5 11.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 7.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5 3.3 GO:0031013 troponin C binding(GO:0030172) calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
0.5 5.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 7.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.4 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.5 2.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 2.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.4 1.3 GO:0008061 chitin binding(GO:0008061)
0.4 4.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.4 4.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 2.8 GO:0043515 kinetochore binding(GO:0043515)
0.4 2.7 GO:0019808 polyamine binding(GO:0019808)
0.4 10.2 GO:0032183 SUMO binding(GO:0032183)
0.4 2.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 2.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 2.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 7.0 GO:0045499 chemorepellent activity(GO:0045499)
0.3 1.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 2.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 5.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 1.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 16.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 4.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 2.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 7.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 3.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 1.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.3 0.9 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 2.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 7.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.3 1.7 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 5.6 GO:0051861 glycolipid binding(GO:0051861)
0.3 4.2 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 2.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 2.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 2.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 3.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 6.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 11.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 2.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 177.5 GO:0005198 structural molecule activity(GO:0005198)
0.2 1.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.2 8.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 3.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 13.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 14.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 1.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 3.8 GO:0043422 protein kinase B binding(GO:0043422)
0.2 3.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 5.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 2.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 14.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 37.7 GO:0044325 ion channel binding(GO:0044325)
0.2 1.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 1.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 0.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 2.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 18.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 12.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 7.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 7.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 3.1 GO:0005521 lamin binding(GO:0005521)
0.1 4.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 3.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 2.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 6.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 3.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.9 GO:0051378 serotonin binding(GO:0051378)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 2.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 16.7 GO:0051015 actin filament binding(GO:0051015)
0.1 0.4 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 14.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 2.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 12.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 5.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 3.4 GO:0030276 clathrin binding(GO:0030276)
0.1 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0071820 N-box binding(GO:0071820)
0.0 14.1 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 3.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 3.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 2.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 4.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 3.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 4.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 4.9 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.5 13.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 24.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 20.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 12.0 PID ATR PATHWAY ATR signaling pathway
0.2 31.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 13.5 NABA COLLAGENS Genes encoding collagen proteins
0.2 5.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 19.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 8.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 4.5 PID ENDOTHELIN PATHWAY Endothelins
0.1 4.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 30.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 10.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 10.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 7.2 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 38.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.7 46.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.5 8.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.5 10.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 27.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 18.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.4 10.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 4.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 5.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 9.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 18.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 5.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 6.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 5.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 10.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 8.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 2.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 3.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 5.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 18.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 4.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 5.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 2.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.7 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 4.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 5.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 6.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 2.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 5.4 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation