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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Crem_Jdp2

Z-value: 2.38

Motif logo

Transcription factors associated with Crem_Jdp2

Gene Symbol Gene ID Gene Info
ENSMUSG00000063889.17 Crem
ENSMUSG00000034271.17 Jdp2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cremmm39_v1_chr18_-_3299452_3299524-0.714.5e-12Click!
Jdp2mm39_v1_chr12_+_85646162_856461900.352.4e-03Click!

Activity profile of Crem_Jdp2 motif

Sorted Z-values of Crem_Jdp2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Crem_Jdp2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_97437709 41.50 ENSMUST00000206984.2
p21 (RAC1) activated kinase 1
chr1_-_79417732 41.17 ENSMUST00000185234.2
ENSMUST00000049972.6
secretogranin II
chr7_-_141649003 33.12 ENSMUST00000039926.10
dual specificity phosphatase 8
chr2_+_155118217 31.99 ENSMUST00000029128.4
microtubule-associated protein 1 light chain 3 alpha
chr2_+_132623198 25.67 ENSMUST00000028826.4
chromogranin B
chr9_-_57375269 22.69 ENSMUST00000215059.2
ENSMUST00000046587.8
ENSMUST00000214256.2
secretory carrier membrane protein 5
chr11_-_6556053 21.55 ENSMUST00000045713.4
NAC alpha domain containing
chrX_-_20787150 21.51 ENSMUST00000081893.7
ENSMUST00000115345.8
synapsin I
chr7_+_112278534 21.51 ENSMUST00000106638.10
TEA domain family member 1
chr9_-_96634874 21.49 ENSMUST00000152594.8
zinc finger and BTB domain containing 38
chr14_+_66581818 20.58 ENSMUST00000118426.8
ENSMUST00000121955.8
ENSMUST00000120229.8
ENSMUST00000134440.2
stathmin-like 4
chr10_+_29087658 20.28 ENSMUST00000213489.2
RIKEN cDNA 9330159F19 gene
chr1_-_36748985 19.97 ENSMUST00000043951.10
ARP1 actin-related protein 1B, centractin beta
chr8_-_24928953 19.22 ENSMUST00000052622.6
transcriptional and immune response regulator
chr14_+_66581745 18.82 ENSMUST00000152093.8
ENSMUST00000074523.13
stathmin-like 4
chr4_-_150736554 18.67 ENSMUST00000117997.2
ENSMUST00000037827.10
solute carrier family 45, member 1
chr3_+_82265474 18.57 ENSMUST00000195471.6
ENSMUST00000195640.2
microtubule-associated protein 9
chr2_+_143388062 18.08 ENSMUST00000028905.10
proprotein convertase subtilisin/kexin type 2
chr3_+_82265351 17.96 ENSMUST00000193559.6
ENSMUST00000192595.6
ENSMUST00000091014.10
microtubule-associated protein 9
chr13_-_34261975 17.33 ENSMUST00000056427.10
tubulin, beta 2A class IIA
chr18_-_35348049 17.23 ENSMUST00000091636.5
ENSMUST00000236680.2
leucine rich repeat transmembrane neuronal 2
chr5_-_114582097 16.74 ENSMUST00000031560.14
methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
chr10_+_29087602 16.47 ENSMUST00000092627.6
RIKEN cDNA 9330159F19 gene
chr7_+_112278520 16.21 ENSMUST00000084705.13
ENSMUST00000239442.2
ENSMUST00000239404.2
ENSMUST00000059768.18
TEA domain family member 1
chr17_-_26727437 15.93 ENSMUST00000236661.2
ENSMUST00000025025.7
dual specificity phosphatase 1
chr6_+_54658609 15.67 ENSMUST00000190641.7
ENSMUST00000187701.2
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_16716989 15.53 ENSMUST00000206129.3
predicted gene, 42372
chr3_-_88455556 15.51 ENSMUST00000131775.2
ENSMUST00000008745.13
RAB25, member RAS oncogene family
chr2_+_136555364 15.42 ENSMUST00000028727.11
ENSMUST00000110098.4
synaptosomal-associated protein 25
chr11_+_101358990 15.19 ENSMUST00000001347.7
Rho family GTPase 2
chr17_-_24908874 15.07 ENSMUST00000007236.5
synaptogyrin 3
chr6_-_124441731 14.90 ENSMUST00000008297.5
calsyntenin 3
chr19_-_5135510 14.68 ENSMUST00000140389.8
ENSMUST00000151413.2
ENSMUST00000077066.8
transmembrane protein 151A
chr9_-_97915227 14.66 ENSMUST00000035027.13
calsyntenin 2
chr7_-_126548671 14.33 ENSMUST00000106339.2
ENSMUST00000052937.12
aspartate beta-hydroxylase domain containing 1
chr5_-_114582053 14.28 ENSMUST00000123256.3
ENSMUST00000112245.6
methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
chr17_+_44263890 14.22 ENSMUST00000177857.9
ENSMUST00000044792.6
regulator of calcineurin 2
chr15_+_79975520 14.12 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr9_-_52591030 13.74 ENSMUST00000213937.2
expressed sequence AI593442
chr11_-_90281721 13.66 ENSMUST00000004051.8
hepatic leukemia factor
chr13_-_54836059 13.53 ENSMUST00000122935.2
ENSMUST00000128257.8
ring finger protein 44
chrX_-_20928219 13.34 ENSMUST00000040628.6
ENSMUST00000115333.9
ENSMUST00000115334.8
zinc finger protein 182
chr2_+_49509288 13.24 ENSMUST00000028102.14
kinesin family member 5C
chr1_-_92401459 12.97 ENSMUST00000185251.2
ENSMUST00000027478.7
NADH:ubiquinone oxidoreductase subunit A10
chr11_+_69920542 12.87 ENSMUST00000232266.2
ENSMUST00000132597.5
discs large MAGUK scaffold protein 4
chr18_+_35347983 12.79 ENSMUST00000235449.2
ENSMUST00000235269.2
catenin (cadherin associated protein), alpha 1
chr7_-_45016138 12.77 ENSMUST00000211067.2
ENSMUST00000003961.16
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr5_+_114582327 12.73 ENSMUST00000137167.8
ENSMUST00000112239.9
ENSMUST00000124260.8
ENSMUST00000125650.6
ENSMUST00000043760.15
mevalonate kinase
chr17_+_44264130 12.58 ENSMUST00000229240.2
regulator of calcineurin 2
chr13_-_54835996 12.53 ENSMUST00000150806.8
ENSMUST00000125927.8
ring finger protein 44
chr13_-_54835878 12.31 ENSMUST00000125871.8
ring finger protein 44
chr1_-_93029532 12.18 ENSMUST00000171796.8
kinesin family member 1A
chr1_-_77491683 12.09 ENSMUST00000186930.2
ENSMUST00000027451.13
ENSMUST00000188797.7
Eph receptor A4
chr9_+_102595628 12.07 ENSMUST00000156485.2
ENSMUST00000145937.2
ENSMUST00000134483.2
ENSMUST00000190047.7
angiomotin-like 2
chr10_-_67748461 12.01 ENSMUST00000064656.8
zinc finger protein 365
chr2_-_130484689 11.78 ENSMUST00000045761.7
leucine zipper, putative tumor suppressor family member 3
chr12_+_102521225 11.58 ENSMUST00000021610.7
chromogranin A
chr16_-_23709564 11.50 ENSMUST00000004480.5
somatostatin
chr11_-_78056347 11.49 ENSMUST00000017530.4
TNF receptor associated factor 4
chr5_+_142946098 11.46 ENSMUST00000031565.15
ENSMUST00000198017.5
fascin actin-bundling protein 1
chr3_-_88669551 11.33 ENSMUST00000183267.2
synaptotagmin XI
chr14_+_47710005 11.29 ENSMUST00000043112.9
ENSMUST00000163324.8
ENSMUST00000228668.2
ENSMUST00000168833.9
F-box protein 34
chr8_+_94537460 11.28 ENSMUST00000034198.15
ENSMUST00000125716.8
guanine nucleotide binding protein, alpha O
chr5_-_124170305 11.26 ENSMUST00000040967.9
vacuolar protein sorting 37B
chr16_-_4608084 11.25 ENSMUST00000118703.8
cell death inducing Trp53 target 1
chr1_-_33946802 11.17 ENSMUST00000115161.8
ENSMUST00000129464.8
ENSMUST00000062289.11
BEN domain containing 6
chr9_+_20914211 11.05 ENSMUST00000214124.2
ENSMUST00000216818.2
mitochondrial ribosomal protein L4
chr1_-_93029547 11.02 ENSMUST00000112958.9
ENSMUST00000186861.2
ENSMUST00000171556.8
kinesin family member 1A
chr3_+_144998233 10.89 ENSMUST00000029848.5
ENSMUST00000139001.2
collagen, type XXIV, alpha 1
chr2_-_109111064 10.87 ENSMUST00000147770.2
methyltransferase like 15
chr9_-_97915036 10.78 ENSMUST00000162295.2
calsyntenin 2
chr10_-_102326286 10.69 ENSMUST00000020040.5
neurotensin
chr7_-_6733411 10.64 ENSMUST00000239104.2
ENSMUST00000051209.11
paternally expressed 3
chr6_-_30304512 10.63 ENSMUST00000094543.3
ENSMUST00000102993.10
ubiquitin-conjugating enzyme E2H
chrX_+_73352694 10.56 ENSMUST00000130581.2
guanosine diphosphate (GDP) dissociation inhibitor 1
chr10_+_44144346 10.27 ENSMUST00000039286.5
autophagy related 5
chr6_-_50543514 10.26 ENSMUST00000161401.2
cytochrome c, somatic
chr5_-_137529251 10.18 ENSMUST00000132525.8
guanine nucleotide binding protein (G protein), beta 2
chr17_-_31731190 10.08 ENSMUST00000237127.2
WD repeat domain 4
chr6_+_124908341 10.05 ENSMUST00000203021.3
myeloid leukemia factor 2
chr12_-_17226889 9.96 ENSMUST00000170580.3
potassium voltage-gated channel, subfamily F, member 1
chr4_-_131565542 9.93 ENSMUST00000030741.9
ENSMUST00000105987.9
protein tyrosine phosphatase, receptor type, U
chr5_-_137529465 9.91 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr9_+_66620959 9.83 ENSMUST00000071889.13
carbonic anhydrase 12
chr9_+_66621001 9.78 ENSMUST00000085420.12
carbonic anhydrase 12
chr15_-_33687986 9.76 ENSMUST00000042021.5
testis-specific protein, Y-encoded-like 5
chr7_-_19043955 9.76 ENSMUST00000207334.2
ENSMUST00000208505.2
ENSMUST00000207716.2
ENSMUST00000208326.2
ENSMUST00000003640.4
FBJ osteosarcoma oncogene B
chr14_+_47710085 9.75 ENSMUST00000095941.9
F-box protein 34
chr6_+_129510145 9.74 ENSMUST00000204487.3
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr11_+_69214895 9.63 ENSMUST00000060956.13
trafficking protein particle complex 1
chr5_-_121329385 9.56 ENSMUST00000054547.9
ENSMUST00000100770.9
protein tyrosine phosphatase, non-receptor type 11
chr11_+_52655461 9.55 ENSMUST00000036796.8
follistatin-like 4
chrX_+_65696608 9.45 ENSMUST00000036043.5
SLIT and NTRK-like family, member 2
chr7_+_130294262 9.42 ENSMUST00000033141.7
transforming, acidic coiled-coil containing protein 2
chr15_-_83989801 9.39 ENSMUST00000229826.2
ENSMUST00000082365.6
sulfotransferase family 4A, member 1
chr17_-_56783376 9.39 ENSMUST00000223859.2
protein tyrosine phosphatase, receptor type, S
chr19_-_61215743 9.31 ENSMUST00000237386.2
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr17_-_56783462 9.27 ENSMUST00000067538.6
protein tyrosine phosphatase, receptor type, S
chr2_-_36026614 9.26 ENSMUST00000122456.8
RNA binding motif protein 18
chr1_-_75240551 9.11 ENSMUST00000186178.7
ENSMUST00000189769.7
ENSMUST00000027404.12
protein tyrosine phosphatase, receptor type, N
chr9_+_20914012 9.04 ENSMUST00000003386.7
mitochondrial ribosomal protein L4
chr6_+_124908439 9.02 ENSMUST00000032214.14
myeloid leukemia factor 2
chr5_-_113285852 9.00 ENSMUST00000212276.2
RIKEN cDNA 2900026A02 gene
chr4_+_21931290 8.99 ENSMUST00000029908.8
failed axon connections homolog
chr8_+_4375212 8.90 ENSMUST00000127460.8
ENSMUST00000136191.8
chemokine (C-C motif) ligand 25
chrX_+_72716756 8.89 ENSMUST00000033752.14
ENSMUST00000114467.9
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr9_-_20638233 8.89 ENSMUST00000217198.2
olfactomedin 2
chr13_-_54759086 8.89 ENSMUST00000049575.8
clathrin, light polypeptide (Lcb)
chr1_-_93029576 8.83 ENSMUST00000190723.7
kinesin family member 1A
chr10_+_79977291 8.74 ENSMUST00000105367.8
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr11_+_110858842 8.69 ENSMUST00000180023.8
ENSMUST00000106636.8
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_+_121575819 8.68 ENSMUST00000065600.8
ENSMUST00000136432.2
cDNA sequence BC048403
chr11_+_69214789 8.65 ENSMUST00000102602.8
trafficking protein particle complex 1
chr6_+_135042649 8.65 ENSMUST00000050104.8
G protein-coupled receptor, family C, group 5, member A
chr11_+_69214883 8.64 ENSMUST00000102601.10
trafficking protein particle complex 1
chr10_-_17823736 8.64 ENSMUST00000037879.8
hdc homolog, cell cycle regulator
chr6_+_124908389 8.55 ENSMUST00000180095.4
myeloid leukemia factor 2
chr7_+_24230063 8.51 ENSMUST00000049020.9
immunity-related GTPase family, Q
chr4_+_42950367 8.44 ENSMUST00000084662.12
DnaJ heat shock protein family (Hsp40) member B5
chr7_+_54485336 8.43 ENSMUST00000082373.8
leucine zipper protein 2
chr11_+_69214971 8.40 ENSMUST00000108662.2
trafficking protein particle complex 1
chr17_-_31731222 8.39 ENSMUST00000236665.2
WD repeat domain 4
chr19_-_34452537 8.25 ENSMUST00000050562.6
cholesterol 25-hydroxylase
chr4_+_85123654 8.19 ENSMUST00000030212.15
ENSMUST00000107189.8
ENSMUST00000107184.8
SH3-domain GRB2-like 2
chr11_+_52122836 8.14 ENSMUST00000037324.12
ENSMUST00000166537.8
S-phase kinase-associated protein 1
chr15_+_12321558 8.13 ENSMUST00000226517.2
golgi phosphoprotein 3
chr8_+_46338557 8.13 ENSMUST00000210422.2
PDZ and LIM domain 3
chrX_+_169106356 8.09 ENSMUST00000178693.4
acetylserotonin O-methyltransferase
chr4_+_141028539 8.09 ENSMUST00000006614.3
Eph receptor A2
chr7_+_130294403 8.08 ENSMUST00000207282.2
transforming, acidic coiled-coil containing protein 2
chr15_-_37459570 8.05 ENSMUST00000119730.8
ENSMUST00000120746.8
neurocalcin delta
chr1_+_24717968 8.04 ENSMUST00000095062.10
LMBR1 domain containing 1
chr6_+_125016723 8.02 ENSMUST00000140131.8
ENSMUST00000032480.14
inhibitor of growth family, member 4
chr13_-_54759145 8.01 ENSMUST00000091609.11
clathrin, light polypeptide (Lcb)
chr8_+_45388466 7.99 ENSMUST00000191428.7
FAT atypical cadherin 1
chr5_+_25427860 7.90 ENSMUST00000045737.14
polypeptide N-acetylgalactosaminyltransferase 11
chr12_+_79177523 7.90 ENSMUST00000021550.7
arginase type II
chr6_-_115569504 7.86 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr4_+_85123358 7.83 ENSMUST00000107188.10
SH3-domain GRB2-like 2
chr6_-_55658242 7.82 ENSMUST00000044767.10
neurogenic differentiation 6
chr11_-_3454766 7.80 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr2_-_36026785 7.73 ENSMUST00000028251.10
RNA binding motif protein 18
chr7_-_7301760 7.65 ENSMUST00000210061.2
chloride channel, voltage-sensitive 4
chr3_-_19749489 7.65 ENSMUST00000061294.5
corticotropin releasing hormone
chr1_+_75456173 7.55 ENSMUST00000113575.9
ENSMUST00000148980.2
ENSMUST00000050899.7
ENSMUST00000187411.2
transmembrane protein 198
chr9_+_40180569 7.53 ENSMUST00000176185.8
sodium channel, voltage-gated, type III, beta
chr17_+_9068805 7.50 ENSMUST00000115720.8
phosphodiesterase 10A
chr6_+_129510117 7.49 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr16_+_57369595 7.44 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr11_+_83193495 7.42 ENSMUST00000176430.8
ENSMUST00000065692.14
ENSMUST00000142680.2
adaptor-related protein complex 2, beta 1 subunit
chr11_+_113510135 7.38 ENSMUST00000146390.3
somatostatin receptor 2
chr2_+_105499233 7.36 ENSMUST00000111086.11
ENSMUST00000111087.10
paired box 6
chrX_+_142447286 7.35 ENSMUST00000112868.8
p21 (RAC1) activated kinase 3
chr9_+_64086553 7.34 ENSMUST00000034965.8
small nuclear RNA activating complex, polypeptide 5
chr11_+_113510207 7.34 ENSMUST00000106630.2
somatostatin receptor 2
chr9_+_40180497 7.31 ENSMUST00000049941.12
sodium channel, voltage-gated, type III, beta
chr11_+_93935156 7.28 ENSMUST00000024979.15
sperm associated antigen 9
chr17_-_24388384 7.27 ENSMUST00000024932.12
ATPase, H+ transporting, lysosomal V0 subunit C
chr15_+_12321620 7.26 ENSMUST00000228671.2
golgi phosphoprotein 3
chr18_-_43925932 7.23 ENSMUST00000237926.2
ENSMUST00000096570.4
predicted gene 94
chr2_+_112285342 7.21 ENSMUST00000069747.6
ER membrane protein complex subunit 7
chr18_+_36481706 7.17 ENSMUST00000235864.2
ENSMUST00000050584.10
cysteine-rich transmembrane module containing 1
chr9_-_45847344 7.16 ENSMUST00000034590.4
transgelin
chr11_+_102992508 7.14 ENSMUST00000107040.10
ENSMUST00000140372.8
ENSMUST00000024492.15
ENSMUST00000134884.8
acyl-Coenzyme A binding domain containing 4
chr11_+_93934940 7.08 ENSMUST00000132079.8
sperm associated antigen 9
chr15_+_81820954 7.05 ENSMUST00000038757.8
ENSMUST00000230633.2
cold shock domain containing C2, RNA binding
chr17_-_33979280 6.99 ENSMUST00000173860.8
RAB11B, member RAS oncogene family
chr5_+_137059127 6.96 ENSMUST00000041543.9
ENSMUST00000186451.2
VGF nerve growth factor inducible
chr16_-_44153498 6.94 ENSMUST00000047446.13
SID1 transmembrane family, member 1
chr11_+_52287239 6.93 ENSMUST00000036952.5
ENSMUST00000109057.8
RIKEN cDNA 9530068E07 gene
chr15_-_77129786 6.91 ENSMUST00000228558.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_8042129 6.86 ENSMUST00000143984.2
TBC1 domain family, member 25
chr8_+_46338498 6.82 ENSMUST00000034053.7
PDZ and LIM domain 3
chr2_+_30127692 6.78 ENSMUST00000113654.8
ENSMUST00000095078.3
leucine rich repeat containing 8A VRAC subunit A
chr11_+_52123016 6.77 ENSMUST00000109072.2
S-phase kinase-associated protein 1
chr10_-_20600797 6.77 ENSMUST00000020165.14
phosphodiesterase 7B
chr7_+_6733684 6.76 ENSMUST00000197117.5
ubiquitin specific peptidase 29
chr3_+_36120128 6.76 ENSMUST00000011492.15
acyl-Coenzyme A dehydrogenase family, member 9
chrX_-_55643429 6.75 ENSMUST00000059899.3
membrane magnesium transporter 1
chr17_+_44389704 6.75 ENSMUST00000154166.8
ENSMUST00000024756.5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr11_-_86561980 6.71 ENSMUST00000143991.3
vacuole membrane protein 1
chr11_-_76134513 6.71 ENSMUST00000017430.12
glyoxalase domain containing 4
chr1_+_75145275 6.60 ENSMUST00000162768.8
ENSMUST00000160439.8
ENSMUST00000027394.12
zinc finger, AN1 type domain 2B
chr19_-_61216834 6.57 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr11_+_93935066 6.56 ENSMUST00000103168.10
sperm associated antigen 9
chr15_-_77129706 6.56 ENSMUST00000228361.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_+_12321502 6.56 ENSMUST00000059680.7
golgi phosphoprotein 3
chr4_+_130001349 6.56 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr5_+_33176160 6.55 ENSMUST00000019109.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr5_+_91287448 6.54 ENSMUST00000031325.6
amphiregulin
chr16_-_4607751 6.53 ENSMUST00000117713.8
cell death inducing Trp53 target 1
chr17_-_35954573 6.46 ENSMUST00000095467.4
mucin like 3
chr18_+_23937019 6.43 ENSMUST00000025127.5
microtubule-associated protein, RP/EB family, member 2
chr11_+_93935021 6.38 ENSMUST00000075695.13
ENSMUST00000092777.11
sperm associated antigen 9
chr16_-_44153288 6.31 ENSMUST00000136381.8
SID1 transmembrane family, member 1
chr11_-_70578905 6.24 ENSMUST00000108544.8
calmodulin binding transcription activator 2
chr5_-_97259302 6.23 ENSMUST00000196078.5
progestin and adipoQ receptor family member III
chr7_+_6733561 6.22 ENSMUST00000200535.6
ubiquitin specific peptidase 29
chr11_-_76134436 6.19 ENSMUST00000164022.8
ENSMUST00000168055.2
ENSMUST00000169701.8
glyoxalase domain containing 4
chr2_-_173118315 6.19 ENSMUST00000036248.13
prostate transmembrane protein, androgen induced 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 37.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
6.0 18.1 GO:0030070 insulin processing(GO:0030070)
5.7 11.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
5.5 22.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
5.2 31.0 GO:0009235 cobalamin metabolic process(GO:0009235)
5.1 15.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
4.0 64.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
4.0 12.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
3.7 18.7 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
3.7 36.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
3.4 27.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
3.3 13.2 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
3.2 9.6 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
3.2 12.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
3.1 9.4 GO:1904633 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
3.0 12.0 GO:0033566 gamma-tubulin complex localization(GO:0033566)
3.0 8.9 GO:0015881 creatine transport(GO:0015881)
2.9 11.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079) regulation of dense core granule biogenesis(GO:2000705)
2.9 17.1 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
2.8 11.3 GO:0021917 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.7 41.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
2.7 8.1 GO:2000019 negative regulation of male gonad development(GO:2000019)
2.7 8.1 GO:0048320 axial mesoderm formation(GO:0048320)
2.5 7.6 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
2.5 10.2 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
2.5 49.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.4 7.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
2.3 11.6 GO:0045054 constitutive secretory pathway(GO:0045054)
2.3 18.5 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
2.3 11.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.2 8.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.2 6.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
2.2 6.6 GO:0006713 glucocorticoid catabolic process(GO:0006713)
2.1 12.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.0 6.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
2.0 8.0 GO:0038016 insulin receptor internalization(GO:0038016)
2.0 19.6 GO:0015670 carbon dioxide transport(GO:0015670)
1.9 48.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.9 5.7 GO:0071288 cellular response to mercury ion(GO:0071288)
1.9 37.7 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.8 5.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.8 3.7 GO:0051795 positive regulation of catagen(GO:0051795)
1.8 5.5 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
1.8 10.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.8 5.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.7 18.7 GO:0033227 dsRNA transport(GO:0033227)
1.6 3.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.6 6.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
1.6 8.0 GO:0097309 cap1 mRNA methylation(GO:0097309)
1.6 16.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.6 7.9 GO:0090467 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
1.5 12.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.5 23.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
1.5 8.9 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.4 5.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.4 10.9 GO:0070475 rRNA base methylation(GO:0070475)
1.4 29.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.3 4.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.3 8.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.3 9.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
1.3 30.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.3 1.3 GO:0061386 closure of optic fissure(GO:0061386)
1.3 3.9 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
1.3 3.9 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.2 14.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.2 7.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.2 3.7 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
1.2 3.6 GO:1903660 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
1.2 7.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.2 4.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.2 3.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.2 7.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.2 3.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
1.2 5.8 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
1.1 14.9 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.1 8.0 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
1.1 4.6 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
1.1 29.7 GO:0007614 short-term memory(GO:0007614)
1.1 5.6 GO:0060279 positive regulation of ovulation(GO:0060279)
1.1 3.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.1 8.9 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
1.1 5.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.0 13.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.0 15.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.0 3.0 GO:0051030 snRNA transport(GO:0051030)
1.0 20.1 GO:0031268 pseudopodium organization(GO:0031268)
1.0 5.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.0 7.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
1.0 3.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.0 6.7 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.9 2.8 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.9 6.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.9 15.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.9 7.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.9 4.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.9 14.7 GO:0030432 peristalsis(GO:0030432)
0.9 5.4 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.9 15.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.9 2.7 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.9 7.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.9 21.5 GO:0001553 luteinization(GO:0001553)
0.9 4.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.9 10.3 GO:0008635 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.8 13.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.8 2.5 GO:0015819 lysine transport(GO:0015819)
0.8 8.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.8 1.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.8 16.3 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.8 5.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.7 11.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.7 6.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.7 3.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.7 2.1 GO:0021764 amygdala development(GO:0021764)
0.7 13.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7 11.6 GO:0043084 penile erection(GO:0043084)
0.7 2.7 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.7 5.4 GO:1901750 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 10.6 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.6 3.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.6 10.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.6 13.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.6 4.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602)
0.6 4.7 GO:0009644 response to high light intensity(GO:0009644)
0.6 8.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.6 5.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.6 8.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.6 5.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353) epithelial fluid transport(GO:0042045)
0.6 11.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 2.8 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.6 3.9 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.6 2.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.6 8.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.5 2.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 5.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.5 4.2 GO:0032790 ribosome disassembly(GO:0032790)
0.5 1.6 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.5 1.6 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.5 7.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.5 3.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.5 6.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.5 6.8 GO:0006824 cobalt ion transport(GO:0006824)
0.5 11.5 GO:0034389 lipid particle organization(GO:0034389)
0.5 5.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.5 4.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.5 6.9 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.5 5.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 3.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 5.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 51.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.4 3.3 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4 3.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4 2.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 22.7 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.4 9.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.4 5.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.4 1.9 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4 1.9 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.4 3.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.4 1.9 GO:0097167 circadian regulation of translation(GO:0097167) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.4 3.0 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.4 4.7 GO:0022615 protein to membrane docking(GO:0022615)
0.4 43.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.4 5.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 3.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 8.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 5.3 GO:0030049 muscle filament sliding(GO:0030049)
0.4 5.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 16.5 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.3 3.5 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 14.6 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 2.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 12.1 GO:0035329 hippo signaling(GO:0035329)
0.3 10.7 GO:0030575 nuclear body organization(GO:0030575)
0.3 4.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.3 5.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 3.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.3 34.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 5.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 20.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 2.8 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.3 1.9 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.3 1.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 3.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.3 2.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 2.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 2.0 GO:2000767 regulation of cytoplasmic translation(GO:2000765) positive regulation of cytoplasmic translation(GO:2000767)
0.3 13.3 GO:0010107 potassium ion import(GO:0010107)
0.3 8.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 0.8 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.3 11.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 3.9 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 3.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.3 4.8 GO:0071625 vocalization behavior(GO:0071625)
0.2 11.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 2.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 2.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 4.4 GO:0021542 dentate gyrus development(GO:0021542)
0.2 3.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2 16.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.2 3.6 GO:0048733 sebaceous gland development(GO:0048733)
0.2 9.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 8.1 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.2 13.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 11.9 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.2 4.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.2 2.6 GO:0072422 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.2 2.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 2.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 2.3 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2 2.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 4.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 5.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 14.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 8.0 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.2 8.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 8.0 GO:0031648 protein destabilization(GO:0031648)
0.2 3.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 2.0 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.2 7.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.2 1.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 5.5 GO:0070918 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.2 2.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.2 3.7 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2 16.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 15.1 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.2 1.4 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.2 0.6 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.2 0.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 3.1 GO:0003094 glomerular filtration(GO:0003094)
0.1 9.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 5.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 9.6 GO:0008542 visual learning(GO:0008542)
0.1 4.7 GO:0010761 fibroblast migration(GO:0010761)
0.1 1.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 11.6 GO:0007030 Golgi organization(GO:0007030)
0.1 20.0 GO:0006275 regulation of DNA replication(GO:0006275)
0.1 3.6 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.1 4.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 14.1 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 14.4 GO:0008645 hexose transport(GO:0008645) glucose transport(GO:0015758)
0.1 1.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 2.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 2.9 GO:0031424 keratinization(GO:0031424)
0.1 1.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 3.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.5 GO:0071470 myeloid dendritic cell differentiation(GO:0043011) cellular response to osmotic stress(GO:0071470)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 2.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 1.3 GO:0034204 lipid translocation(GO:0034204)
0.1 0.9 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 2.3 GO:0045109 intermediate filament organization(GO:0045109)
0.1 2.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 3.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 6.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 3.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 6.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 2.0 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 1.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 3.5 GO:0060612 adipose tissue development(GO:0060612)
0.1 4.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 4.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 0.7 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.3 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 4.2 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 10.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 2.8 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 20.3 GO:0007015 actin filament organization(GO:0007015)
0.1 5.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 5.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 5.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 3.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 5.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.4 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 1.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 8.3 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 10.8 GO:0006412 translation(GO:0006412)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 2.0 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 7.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.4 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 3.7 GO:0016358 dendrite development(GO:0016358)
0.0 21.0 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.2 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 3.1 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 27.1 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 1.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 2.9 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.3 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 1.7 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 3.2 GO:0030334 regulation of cell migration(GO:0030334)
0.0 1.0 GO:0007596 blood coagulation(GO:0007596)
0.0 2.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 6.4 GO:0048666 neuron development(GO:0048666)
0.0 0.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 10.8 GO:0006952 defense response(GO:0006952)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 37.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
7.2 21.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
4.1 12.4 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
4.1 20.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
3.5 20.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
3.4 10.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
3.3 36.5 GO:0000235 astral microtubule(GO:0000235)
3.1 9.4 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
3.1 15.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
2.3 11.5 GO:0044393 microspike(GO:0044393)
2.3 45.6 GO:0031045 dense core granule(GO:0031045)
2.1 61.0 GO:0000421 autophagosome membrane(GO:0000421)
1.9 11.6 GO:0042583 chromaffin granule(GO:0042583)
1.9 41.5 GO:0071437 invadopodium(GO:0071437)
1.6 23.8 GO:0005869 dynactin complex(GO:0005869)
1.5 16.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.5 35.3 GO:0030008 TRAPP complex(GO:0030008)
1.3 5.2 GO:0046691 intracellular canaliculus(GO:0046691)
1.1 14.4 GO:0072546 ER membrane protein complex(GO:0072546)
1.1 4.3 GO:0005745 m-AAA complex(GO:0005745)
1.0 8.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.9 7.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.9 4.5 GO:0035976 AP1 complex(GO:0035976)
0.9 5.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.9 12.8 GO:0005915 zonula adherens(GO:0005915)
0.9 4.3 GO:0035363 histone locus body(GO:0035363)
0.8 4.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 18.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8 11.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.8 37.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.8 3.2 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.8 4.7 GO:0070820 tertiary granule(GO:0070820)
0.8 44.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.8 15.5 GO:0031143 pseudopodium(GO:0031143)
0.7 2.9 GO:0097447 dendritic tree(GO:0097447)
0.7 3.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.7 26.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.7 4.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.6 4.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.6 5.7 GO:0005577 fibrinogen complex(GO:0005577)
0.6 4.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 14.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 8.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.5 3.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.5 24.3 GO:0031901 early endosome membrane(GO:0031901)
0.5 2.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 3.6 GO:0070847 core mediator complex(GO:0070847)
0.4 31.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 10.3 GO:0043196 varicosity(GO:0043196)
0.4 2.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 4.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.4 6.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 7.1 GO:0042581 specific granule(GO:0042581)
0.4 7.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 12.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 3.1 GO:0000322 storage vacuole(GO:0000322)
0.4 6.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.4 31.3 GO:0031985 Golgi cisterna(GO:0031985)
0.4 8.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 21.0 GO:0005776 autophagosome(GO:0005776)
0.3 5.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 20.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 1.8 GO:0033263 CORVET complex(GO:0033263)
0.3 7.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 14.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 12.8 GO:0048786 presynaptic active zone(GO:0048786)
0.3 5.8 GO:1904115 axon cytoplasm(GO:1904115)
0.3 3.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 96.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 12.9 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.2 33.0 GO:0008021 synaptic vesicle(GO:0008021)
0.2 4.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 6.4 GO:0035371 microtubule plus-end(GO:0035371)
0.2 2.1 GO:0000813 ESCRT I complex(GO:0000813)
0.2 5.0 GO:0016460 myosin II complex(GO:0016460)
0.2 3.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 1.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 2.0 GO:0030478 actin cap(GO:0030478)
0.2 2.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 22.3 GO:0043679 axon terminus(GO:0043679)
0.2 3.4 GO:0000974 Prp19 complex(GO:0000974)
0.2 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.3 GO:0045098 type III intermediate filament(GO:0045098)
0.2 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 40.9 GO:0005769 early endosome(GO:0005769)
0.2 20.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 3.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 25.6 GO:0043204 perikaryon(GO:0043204)
0.2 9.4 GO:0032587 ruffle membrane(GO:0032587)
0.2 18.5 GO:0036477 somatodendritic compartment(GO:0036477)
0.2 1.9 GO:0097542 ciliary tip(GO:0097542)
0.1 7.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 13.1 GO:0030018 Z disc(GO:0030018)
0.1 24.9 GO:0005923 bicellular tight junction(GO:0005923)
0.1 11.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 7.4 GO:0001533 cornified envelope(GO:0001533)
0.1 5.9 GO:0055037 recycling endosome(GO:0055037)
0.1 5.5 GO:0014704 intercalated disc(GO:0014704)
0.1 1.1 GO:0070652 HAUS complex(GO:0070652)
0.1 12.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 23.5 GO:0030027 lamellipodium(GO:0030027)
0.1 118.6 GO:0043005 neuron projection(GO:0043005)
0.1 13.1 GO:0016605 PML body(GO:0016605)
0.1 3.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 11.0 GO:0045177 apical part of cell(GO:0045177)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 10.9 GO:0005581 collagen trimer(GO:0005581)
0.1 3.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 46.2 GO:0005768 endosome(GO:0005768)
0.1 21.5 GO:0072562 blood microparticle(GO:0072562)
0.1 3.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.9 GO:0001772 immunological synapse(GO:0001772)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 9.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 13.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 21.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 15.6 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 3.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 93.9 GO:0005739 mitochondrion(GO:0005739)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.1 1.1 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 256.3 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 9.2 GO:0005925 focal adhesion(GO:0005925)
0.0 3.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 91.9 GO:0005576 extracellular region(GO:0005576)
0.0 3.3 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0030017 sarcomere(GO:0030017)
0.0 1.6 GO:0030054 cell junction(GO:0030054)
0.0 11.0 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
5.3 15.9 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
4.6 18.5 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
3.4 10.3 GO:0019776 Atg8 ligase activity(GO:0019776)
3.3 29.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.1 18.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
3.0 8.9 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
2.9 17.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
2.7 8.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
2.6 10.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
2.6 7.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
2.5 27.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
2.5 14.7 GO:0004994 somatostatin receptor activity(GO:0004994)
2.4 9.8 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
2.2 8.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
2.2 13.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
2.2 10.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
2.0 6.1 GO:0047312 L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
1.9 18.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.9 14.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.8 12.9 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.8 5.5 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
1.8 27.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.8 7.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.8 40.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.7 5.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.7 6.9 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
1.7 12.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.7 5.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.6 27.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.6 4.7 GO:0004947 bradykinin receptor activity(GO:0004947)
1.5 6.0 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
1.4 2.9 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
1.4 4.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
1.4 11.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
1.4 5.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.3 8.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.3 11.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.2 7.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.2 4.8 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
1.2 9.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.2 22.3 GO:0030957 Tat protein binding(GO:0030957)
1.2 3.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.1 17.2 GO:0042043 neurexin family protein binding(GO:0042043)
1.1 16.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.1 3.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.1 4.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.1 31.7 GO:0031489 myosin V binding(GO:0031489)
1.1 19.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.0 41.2 GO:0042056 chemoattractant activity(GO:0042056)
1.0 9.2 GO:0032564 dATP binding(GO:0032564)
1.0 12.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.9 10.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.9 2.7 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.9 24.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.9 3.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.9 3.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.8 2.4 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.8 12.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.8 11.5 GO:0031996 thioesterase binding(GO:0031996)
0.8 6.8 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.7 5.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.7 5.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 2.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.7 9.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.7 8.0 GO:0031419 cobalamin binding(GO:0031419)
0.7 16.1 GO:0002162 dystroglycan binding(GO:0002162)
0.7 2.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.7 7.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7 3.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.7 14.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 2.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.7 4.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.7 6.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.7 22.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.7 3.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 3.9 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.7 36.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.7 20.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.6 6.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 22.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 3.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.6 10.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 2.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.6 4.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.6 56.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.6 5.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.6 4.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.6 24.2 GO:0070412 R-SMAD binding(GO:0070412)
0.6 5.7 GO:0045340 mercury ion binding(GO:0045340)
0.6 3.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 8.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.5 6.8 GO:0035473 lipase binding(GO:0035473)
0.5 2.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 18.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.5 5.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.5 2.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 5.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.5 1.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 3.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 8.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 2.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 5.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 12.8 GO:0017166 vinculin binding(GO:0017166)
0.4 13.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 20.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.4 4.5 GO:0002151 G-quadruplex RNA binding(GO:0002151) G-quadruplex DNA binding(GO:0051880)
0.4 39.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 5.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 8.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.4 7.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 1.9 GO:0004370 glycerol kinase activity(GO:0004370)
0.4 1.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.4 17.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 13.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.4 1.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4 1.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.4 7.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 7.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 21.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 14.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 6.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.3 31.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3 3.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 3.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.3 6.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 5.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 14.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 4.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 18.7 GO:0030276 clathrin binding(GO:0030276)
0.3 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 5.8 GO:0050811 GABA receptor binding(GO:0050811)
0.3 15.1 GO:0042169 SH2 domain binding(GO:0042169)
0.3 3.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 0.8 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.3 12.1 GO:0071837 HMG box domain binding(GO:0071837)
0.3 0.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 9.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 3.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 13.7 GO:0050699 WW domain binding(GO:0050699)
0.2 2.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 3.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.9 GO:0032451 demethylase activity(GO:0032451)
0.2 4.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 3.1 GO:0008097 5S rRNA binding(GO:0008097)
0.2 3.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 10.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.8 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 75.2 GO:0015631 tubulin binding(GO:0015631)
0.2 1.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 1.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 12.0 GO:0009055 electron carrier activity(GO:0009055)
0.2 9.9 GO:0030507 spectrin binding(GO:0030507)
0.2 3.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 36.6 GO:0051015 actin filament binding(GO:0051015)
0.2 5.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 26.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 3.0 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 14.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 4.7 GO:0070888 E-box binding(GO:0070888)
0.2 2.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 11.8 GO:0043621 protein self-association(GO:0043621)
0.1 2.3 GO:0048156 tau protein binding(GO:0048156)
0.1 10.4 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 3.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 9.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 17.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 8.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 6.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 6.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 4.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 8.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 7.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 14.3 GO:0051213 dioxygenase activity(GO:0051213)
0.1 38.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 9.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 5.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 46.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 14.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 10.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 21.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 3.6 GO:0005109 frizzled binding(GO:0005109)
0.1 11.5 GO:0005179 hormone activity(GO:0005179)
0.1 2.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 21.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 8.5 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.9 GO:0031491 nucleosome binding(GO:0031491)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 5.4 GO:0005518 collagen binding(GO:0005518)
0.1 45.2 GO:0005509 calcium ion binding(GO:0005509)
0.1 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 13.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 8.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.1 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 8.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 16.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 4.6 GO:0004497 monooxygenase activity(GO:0004497)
0.1 2.2 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.1 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.5 GO:0002039 p53 binding(GO:0002039)
0.0 2.4 GO:0046906 tetrapyrrole binding(GO:0046906)
0.0 25.0 GO:0008289 lipid binding(GO:0008289)
0.0 4.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 3.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 5.0 GO:0003779 actin binding(GO:0003779)
0.0 3.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 4.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 7.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 9.5 GO:0005102 receptor binding(GO:0005102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 99.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.9 9.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.8 25.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.8 27.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.7 26.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 16.9 PID ARF 3PATHWAY Arf1 pathway
0.6 21.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.6 20.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.6 40.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.6 28.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.6 3.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 7.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 15.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 5.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 22.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 13.3 PID RHOA PATHWAY RhoA signaling pathway
0.3 25.1 PID AP1 PATHWAY AP-1 transcription factor network
0.3 13.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 8.9 ST GA12 PATHWAY G alpha 12 Pathway
0.2 14.3 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 5.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 10.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 7.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 5.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 9.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 13.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 8.8 PID LKB1 PATHWAY LKB1 signaling events
0.2 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 10.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 10.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 18.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.4 PID AURORA A PATHWAY Aurora A signaling
0.1 4.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 3.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.6 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 15.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 2.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 41.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
2.4 41.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.4 16.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.2 23.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.9 37.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9 18.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.8 16.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.7 14.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.7 9.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.7 20.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.7 37.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.6 11.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.6 8.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 9.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.5 11.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 14.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 8.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 2.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 21.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 10.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.4 7.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 3.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 11.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 12.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 26.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 11.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 10.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 5.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 5.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 15.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 8.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 3.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 53.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 3.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 15.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 6.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 12.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.2 12.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 7.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 2.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 8.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 4.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 7.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 7.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 14.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 9.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 4.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 15.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 3.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 14.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 6.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 7.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 27.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 11.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 2.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 5.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 4.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 6.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 8.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 6.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 15.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 2.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 9.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.4 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production