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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Crx_Gsc

Z-value: 0.79

Motif logo

Transcription factors associated with Crx_Gsc

Gene Symbol Gene ID Gene Info
ENSMUSG00000041578.16 Crx
ENSMUSG00000021095.6 Gsc

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gscmm39_v1_chr12_-_104439589_104439633-0.326.8e-03Click!
Crxmm39_v1_chr7_-_15613769_15613893-0.085.3e-01Click!

Activity profile of Crx_Gsc motif

Sorted Z-values of Crx_Gsc motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Crx_Gsc

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_33614378 7.18 ENSMUST00000115044.8
mucin 13, epithelial transmembrane
chr6_-_69553484 6.88 ENSMUST00000103357.4
immunoglobulin kappa variable 4-57
chr12_-_114621406 6.83 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr6_-_69204417 5.72 ENSMUST00000103346.3
immunoglobulin kappa chain variable 4-72
chr14_-_68819544 5.47 ENSMUST00000022641.9
ADAM-like, decysin 1
chr6_-_69245427 5.10 ENSMUST00000103348.3
immunoglobulin kappa chain variable 4-70
chr6_-_68713748 4.65 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr6_-_59403264 4.47 ENSMUST00000051065.6
GPRIN family member 3
chr7_-_79497940 4.32 ENSMUST00000107392.8
alanyl (membrane) aminopeptidase
chr7_-_79497922 4.31 ENSMUST00000205502.2
alanyl (membrane) aminopeptidase
chr16_+_33614715 4.25 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr6_+_68247469 4.07 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr10_+_127478844 3.99 ENSMUST00000092074.12
ENSMUST00000120279.2
signal transducer and activator of transcription 6
chr12_-_113379925 3.95 ENSMUST00000194162.6
ENSMUST00000192250.2
immunoglobulin heavy constant delta
chr6_-_68746087 3.82 ENSMUST00000103333.4
immunoglobulin kappa chain variable 4-91
chr12_-_114646685 3.67 ENSMUST00000194350.6
ENSMUST00000103504.3
immunoglobulin heavy variable V1-18
chr12_-_114752425 3.57 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr12_-_114263874 3.54 ENSMUST00000103482.2
ENSMUST00000194159.2
immunoglobulin heavy variable 9-4
chr3_-_16060545 3.39 ENSMUST00000194367.6
predicted gene 5150
chr12_+_79177523 3.35 ENSMUST00000021550.7
arginase type II
chr12_-_113823290 3.29 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr8_+_22224506 3.28 ENSMUST00000080533.6
defensin, alpha, 24
chr12_-_115587215 3.16 ENSMUST00000199933.5
ENSMUST00000103539.3
immunoglobulin heavy variable 1-69
chr3_-_16060491 3.10 ENSMUST00000108347.3
predicted gene 5150
chr11_+_70396070 2.92 ENSMUST00000019063.3
transmembrane 4 superfamily member 5
chr9_-_46146558 2.79 ENSMUST00000121916.8
ENSMUST00000034586.9
apolipoprotein C-III
chr3_-_144555062 2.76 ENSMUST00000159989.2
chloride channel accessory 3B
chr14_+_51193449 2.74 ENSMUST00000095925.5
purine-nucleoside phosphorylase 2
chr12_-_115157739 2.72 ENSMUST00000103525.3
immunoglobulin heavy variable V1-54
chr15_-_76501041 2.52 ENSMUST00000073428.7
solute carrier family 39 (zinc transporter), member 4
chr1_+_93789068 2.40 ENSMUST00000094663.4
galactose-3-O-sulfotransferase 2
chr9_-_46146928 2.37 ENSMUST00000118649.8
apolipoprotein C-III
chr1_-_87029312 2.35 ENSMUST00000113270.3
alkaline phosphatase, intestinal
chr17_+_34416707 2.25 ENSMUST00000025196.9
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr12_-_114901026 2.21 ENSMUST00000103516.2
ENSMUST00000191868.2
immunoglobulin heavy variable V1-42
chr5_+_53195423 2.18 ENSMUST00000170523.8
solute carrier family 34 (sodium phosphate), member 2
chr15_-_75766321 2.12 ENSMUST00000023237.8
nicotinate phosphoribosyltransferase
chr19_+_43678109 2.11 ENSMUST00000081079.6
ectonucleoside triphosphate diphosphohydrolase 7
chr5_-_143963413 2.07 ENSMUST00000031622.13
oncomodulin
chr10_-_75617245 2.07 ENSMUST00000001715.10
glutathione S-transferase, theta 3
chr17_+_34416689 2.06 ENSMUST00000173441.9
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr3_+_28752050 2.05 ENSMUST00000029240.14
solute carrier family 2 (facilitated glucose transporter), member 2
chr1_+_93855759 2.03 ENSMUST00000177958.2
galactose-3-O-sulfotransferase 2B
chr1_+_172328768 1.98 ENSMUST00000111228.2
transgelin 2
chr11_+_3981769 1.98 ENSMUST00000019512.8
SEC14-like lipid binding 4
chr17_+_87943401 1.98 ENSMUST00000235125.2
ENSMUST00000053577.9
ENSMUST00000234009.2
epithelial cell adhesion molecule
chr1_+_93789548 1.97 ENSMUST00000187896.2
galactose-3-O-sulfotransferase 2
chr3_-_73615535 1.96 ENSMUST00000138216.8
butyrylcholinesterase
chr16_+_23109213 1.93 ENSMUST00000115335.2
beta galactoside alpha 2,6 sialyltransferase 1
chr13_+_19362068 1.92 ENSMUST00000103553.3
T cell receptor gamma, variable 7
chr2_+_3771709 1.85 ENSMUST00000177037.2
family with sequence similarity 107, member B
chr17_-_35077089 1.81 ENSMUST00000153400.8
complement factor B
chr6_+_123206802 1.80 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chr6_+_123206880 1.76 ENSMUST00000205129.2
C-type lectin domain family 4, member n
chr15_-_76501525 1.74 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr14_-_87378641 1.72 ENSMUST00000168889.3
ENSMUST00000022599.14
diaphanous related formin 3
chr6_-_68887957 1.68 ENSMUST00000200454.2
immunoglobulin kappa variable 4-86
chr3_-_73615732 1.67 ENSMUST00000029367.6
butyrylcholinesterase
chr6_+_119213468 1.67 ENSMUST00000238905.2
ENSMUST00000037434.13
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr18_-_73948501 1.66 ENSMUST00000025439.5
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr5_+_117258185 1.65 ENSMUST00000111978.8
TAO kinase 3
chr2_+_24275321 1.62 ENSMUST00000056641.15
ENSMUST00000142522.8
ENSMUST00000131930.2
pleckstrin and Sec7 domain containing 4
chr3_+_103767581 1.61 ENSMUST00000029433.9
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr6_-_68887922 1.58 ENSMUST00000103337.3
immunoglobulin kappa variable 4-86
chr5_-_104125270 1.58 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr8_+_79235946 1.58 ENSMUST00000209490.2
ENSMUST00000034111.10
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr11_-_116080361 1.57 ENSMUST00000148601.2
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_16958647 1.56 ENSMUST00000102881.10
pleckstrin
chr11_-_101998648 1.53 ENSMUST00000177304.8
ENSMUST00000017455.15
peptide YY
chr5_+_104447037 1.52 ENSMUST00000031246.9
integrin binding sialoprotein
chr3_+_128993609 1.52 ENSMUST00000173645.4
paired-like homeodomain transcription factor 2
chr11_-_40624200 1.51 ENSMUST00000020579.9
hyaluronan mediated motility receptor (RHAMM)
chr5_-_104125192 1.45 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr17_+_34124078 1.45 ENSMUST00000172817.2
small integral membrane protein 40
chr17_-_87573294 1.44 ENSMUST00000145895.8
ENSMUST00000129616.8
ENSMUST00000155904.2
ENSMUST00000151155.8
ENSMUST00000144236.9
ENSMUST00000024963.11
multiple coagulation factor deficiency 2
chr5_-_28442871 1.44 ENSMUST00000120068.2
canopy FGF signaling regulator 1
chr10_+_75778885 1.43 ENSMUST00000121151.2
pre-B lymphocyte gene 3
chr18_+_70058613 1.39 ENSMUST00000080050.6
coiled-coil domain containing 68
chr11_-_70350783 1.39 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chr11_-_99176086 1.39 ENSMUST00000017255.4
keratin 24
chr14_+_54431947 1.37 ENSMUST00000103715.2
T cell receptor alpha joining 26
chr7_+_99827886 1.37 ENSMUST00000207358.2
ENSMUST00000207995.2
ENSMUST00000049333.13
ENSMUST00000170954.10
ENSMUST00000179842.3
ENSMUST00000208260.2
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr4_-_140805613 1.37 ENSMUST00000030760.15
NECAP endocytosis associated 2
chr1_+_171265103 1.36 ENSMUST00000043839.5
F11 receptor
chr13_-_74918745 1.35 ENSMUST00000223033.2
ENSMUST00000222588.2
calpastatin
chr1_-_126665904 1.35 ENSMUST00000160693.2
NCK-associated protein 5
chr12_-_114528632 1.34 ENSMUST00000195337.2
ENSMUST00000103497.2
immunoglobulin heavy variable V15-2
chr6_+_122898764 1.33 ENSMUST00000060484.9
C-type lectin domain family 4, member a1
chr9_+_123596276 1.32 ENSMUST00000166236.9
ENSMUST00000111454.4
ENSMUST00000168910.2
chemokine (C-C motif) receptor 9
chr7_-_101765970 1.31 ENSMUST00000211408.2
cholinergic receptor, nicotinic, alpha polypeptide 10
chr9_+_88209250 1.31 ENSMUST00000034992.8
5' nucleotidase, ecto
chr11_+_83553400 1.30 ENSMUST00000019074.4
chemokine (C-C motif) ligand 4
chr13_+_21995906 1.30 ENSMUST00000104941.4
H4 clustered histone 17
chr19_+_3373285 1.29 ENSMUST00000025835.6
carnitine palmitoyltransferase 1a, liver
chr9_-_50528727 1.28 ENSMUST00000131351.8
ENSMUST00000171462.8
NKAP domain containing 1
chr19_+_11469386 1.26 ENSMUST00000079855.11
predicted gene 8369
chrX_-_101232978 1.26 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr19_-_5416626 1.25 ENSMUST00000237167.2
BAF nuclear assembly factor 1
chr5_-_143963461 1.25 ENSMUST00000110702.2
oncomodulin
chr12_-_115206715 1.23 ENSMUST00000103527.2
ENSMUST00000194071.2
immunoglobulin heavy variable 1-56
chr16_+_36004452 1.22 ENSMUST00000114858.2
cystatin domain containing 4
chr18_+_70058533 1.22 ENSMUST00000043929.11
coiled-coil domain containing 68
chr1_+_178014983 1.21 ENSMUST00000161075.8
ENSMUST00000027783.14
desumoylating isopeptidase 2
chr6_+_41165156 1.21 ENSMUST00000103277.2
T cell receptor beta, variable 20
chr6_+_119213541 1.20 ENSMUST00000186622.3
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr3_-_113198765 1.20 ENSMUST00000179568.3
amylase 2a4
chr9_+_108880158 1.18 ENSMUST00000198708.5
shisa family member 5
chr4_+_130640436 1.17 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr5_-_104125226 1.16 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr5_+_77413282 1.15 ENSMUST00000080359.12
RE1-silencing transcription factor
chr10_-_59452489 1.13 ENSMUST00000020312.13
mitochondrial calcium uniporter
chr19_-_5416339 1.12 ENSMUST00000170010.3
BAF nuclear assembly factor 1
chr19_+_5416769 1.11 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr9_-_50528530 1.09 ENSMUST00000147671.2
ENSMUST00000145139.8
ENSMUST00000155435.8
NKAP domain containing 1
chr5_-_66309244 1.09 ENSMUST00000167950.8
RNA binding motif protein 47
chr7_-_110581652 1.08 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr13_-_74918701 1.07 ENSMUST00000223126.2
calpastatin
chr5_+_122348140 1.05 ENSMUST00000196187.5
ENSMUST00000100747.3
hydrogen voltage-gated channel 1
chr6_-_113717689 1.03 ENSMUST00000032440.6
SEC13 homolog, nuclear pore and COPII coat complex component
chr13_-_64645606 1.02 ENSMUST00000180282.2
family with sequence similarity 240 member B
chr7_+_19753097 1.01 ENSMUST00000117909.2
NLR family, pyrin domain containing 9B
chr1_+_178015287 1.01 ENSMUST00000159284.2
desumoylating isopeptidase 2
chr4_-_133360749 1.00 ENSMUST00000084238.5
zinc finger, DHHC domain containing 18
chr10_-_86843878 0.98 ENSMUST00000035288.17
stabilin 2
chr11_-_109364046 0.98 ENSMUST00000070872.13
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_+_73931679 0.97 ENSMUST00000098006.9
ENSMUST00000084474.6
FERM domain containing 3
chr6_+_34843896 0.96 ENSMUST00000202999.2
transmembrane protein 140
chr19_-_4189603 0.95 ENSMUST00000025761.8
calcium binding protein 4
chr6_+_117877272 0.94 ENSMUST00000177743.8
ENSMUST00000167182.8
heterogeneous nuclear ribonucleoprotein F
chr5_-_65248927 0.94 ENSMUST00000043352.8
transmembrane protein 156
chr5_+_64316771 0.92 ENSMUST00000043893.13
TBC1 domain family, member 1
chr1_-_165021879 0.92 ENSMUST00000043338.10
SFT2 domain containing 2
chr17_-_13211374 0.90 ENSMUST00000159551.8
ENSMUST00000160781.8
Wilms tumour 1-associating protein
chr2_-_144112444 0.88 ENSMUST00000028909.5
sorting nexin 5
chr11_+_5470652 0.84 ENSMUST00000063084.16
X-box binding protein 1
chr10_-_51466567 0.84 ENSMUST00000020064.5
family with sequence similarity 162, member B
chr1_-_189420270 0.84 ENSMUST00000171929.8
ENSMUST00000165962.2
centromere protein F
chr1_+_24717968 0.83 ENSMUST00000095062.10
LMBR1 domain containing 1
chr5_-_137529465 0.83 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr1_-_74233790 0.83 ENSMUST00000053389.5
chemokine (C-X-C motif) receptor 1
chr7_+_92524460 0.82 ENSMUST00000076052.8
prolylcarboxypeptidase (angiotensinase C)
chr6_-_5193757 0.82 ENSMUST00000177159.9
ENSMUST00000176945.2
paraoxonase 1
chr7_+_24584197 0.81 ENSMUST00000156372.8
ENSMUST00000124035.2
ribosomal protein S19
chr11_-_66059270 0.81 ENSMUST00000108691.2
dynein, axonemal, heavy chain 9
chr7_+_28510350 0.78 ENSMUST00000174477.8
heterogeneous nuclear ribonucleoprotein L
chr15_-_76524097 0.78 ENSMUST00000168185.8
tonsoku-like, DNA repair protein
chr18_-_70274639 0.77 ENSMUST00000121693.8
RAB27B, member RAS oncogene family
chr1_-_149798090 0.77 ENSMUST00000111926.9
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr16_-_16687119 0.75 ENSMUST00000075017.5
pre-B lymphocyte gene 1
chr6_-_69220672 0.75 ENSMUST00000196201.2
immunoglobulin kappa chain variable 4-71
chr9_-_106768601 0.73 ENSMUST00000069036.14
mesencephalic astrocyte-derived neurotrophic factor
chr7_+_92524495 0.71 ENSMUST00000207594.2
prolylcarboxypeptidase (angiotensinase C)
chr2_+_121188195 0.71 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr13_+_108182941 0.71 ENSMUST00000224361.2
ENSMUST00000224390.2
small integral membrane protein 15
chr18_-_74340885 0.71 ENSMUST00000177604.2
spindle and kinetochore associated complex subunit 1
chr1_+_24717793 0.70 ENSMUST00000186190.2
LMBR1 domain containing 1
chr1_-_153363354 0.69 ENSMUST00000186380.7
ENSMUST00000188345.2
ENSMUST00000042141.12
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr5_-_92426014 0.69 ENSMUST00000159345.8
ENSMUST00000113102.10
N-acylethanolamine acid amidase
chr6_+_113508636 0.69 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr10_+_76284907 0.69 ENSMUST00000092406.12
RIKEN cDNA 2610028H24 gene
chr7_-_63588610 0.69 ENSMUST00000063694.10
Kruppel-like factor 13
chr6_-_5193816 0.68 ENSMUST00000002663.12
paraoxonase 1
chr18_+_84869883 0.68 ENSMUST00000163083.2
cytochrome b5 type A (microsomal)
chr18_-_74340842 0.66 ENSMUST00000040188.16
spindle and kinetochore associated complex subunit 1
chr11_+_96355413 0.66 ENSMUST00000103154.11
ENSMUST00000100521.10
ENSMUST00000100519.11
src family associated phosphoprotein 1
chr7_+_28510310 0.66 ENSMUST00000038572.15
heterogeneous nuclear ribonucleoprotein L
chr7_-_110581376 0.65 ENSMUST00000154466.2
inositol 1,4,5-triphosphate receptor associated 1
chr6_-_134543876 0.65 ENSMUST00000032322.15
ENSMUST00000126836.4
low density lipoprotein receptor-related protein 6
chr11_+_117090465 0.64 ENSMUST00000093907.11
septin 9
chr4_+_33062999 0.64 ENSMUST00000108162.8
ENSMUST00000024035.9
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr14_+_54183465 0.64 ENSMUST00000197130.5
ENSMUST00000103677.3
T cell receptor delta variable 2-1
chr12_-_84447625 0.64 ENSMUST00000117286.2
ectonucleoside triphosphate diphosphohydrolase 5
chr1_+_24717722 0.63 ENSMUST00000186096.7
LMBR1 domain containing 1
chr19_+_4189786 0.62 ENSMUST00000096338.5
G protein-coupled receptor 152
chr8_-_73246435 0.61 ENSMUST00000152080.8
solute carrier family 35, member E1
chr7_-_45375205 0.61 ENSMUST00000094424.7
sperm acrosome associated 4
chr11_-_120489172 0.59 ENSMUST00000026125.3
Aly/REF export factor
chr7_+_99243812 0.59 ENSMUST00000162290.2
arrestin, beta 1
chr14_-_64654397 0.59 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr4_+_80752535 0.58 ENSMUST00000102831.8
tyrosinase-related protein 1
chr1_+_24717711 0.57 ENSMUST00000191471.7
LMBR1 domain containing 1
chr11_-_66059330 0.57 ENSMUST00000080665.10
dynein, axonemal, heavy chain 9
chr14_+_26722319 0.57 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr12_-_118162652 0.57 ENSMUST00000084806.7
dynein, axonemal, heavy chain 11
chrX_+_72527208 0.57 ENSMUST00000033741.15
ENSMUST00000169489.2
biglycan
chr1_-_119576347 0.56 ENSMUST00000027632.14
ENSMUST00000187194.2
erythrocyte membrane protein band 4.1 like 5
chr11_-_109363406 0.56 ENSMUST00000168740.3
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr10_-_75673175 0.56 ENSMUST00000220440.2
glutathione S-transferase, theta 2
chr12_+_85645801 0.56 ENSMUST00000177587.9
Jun dimerization protein 2
chr8_-_108129829 0.55 ENSMUST00000003947.9
NAD(P)H dehydrogenase, quinone 1
chr7_+_26534730 0.54 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr5_-_123859153 0.54 ENSMUST00000196282.5
zinc finger, CCHC domain containing 8
chrX_-_99670174 0.53 ENSMUST00000015812.12
PDZ domain containing 11
chr16_+_91184661 0.53 ENSMUST00000139503.2
interferon (alpha and beta) receptor 2
chr7_-_103492361 0.53 ENSMUST00000063957.6
hemoglobin Z, beta-like embryonic chain
chrX_+_73468140 0.53 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr6_-_93889483 0.52 ENSMUST00000205116.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_-_82777746 0.50 ENSMUST00000156055.2
ENSMUST00000030110.15
zinc finger, DHHC domain containing 21
chr11_+_96355441 0.50 ENSMUST00000071510.14
ENSMUST00000107662.9
src family associated phosphoprotein 1
chr14_+_8555284 0.48 ENSMUST00000144914.3
predicted gene 281

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.0 4.0 GO:0035771 T-helper 1 cell lineage commitment(GO:0002296) interleukin-4-mediated signaling pathway(GO:0035771)
0.9 4.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.8 1.6 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.8 2.4 GO:0019043 establishment of viral latency(GO:0019043)
0.7 3.7 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 2.7 GO:0038016 insulin receptor internalization(GO:0038016)
0.7 11.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.7 3.4 GO:0010958 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.6 3.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.5 1.6 GO:0010925 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.5 1.5 GO:1902617 response to fluoride(GO:1902617)
0.4 1.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.4 2.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.4 2.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 1.9 GO:1990743 protein sialylation(GO:1990743)
0.4 1.5 GO:0002353 plasma kallikrein-kinin cascade(GO:0002353)
0.4 8.0 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.4 2.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 1.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.3 1.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.3 1.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.3 1.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 0.3 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.3 1.5 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.3 4.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 1.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.3 0.8 GO:0009087 methionine catabolic process(GO:0009087)
0.3 1.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 0.7 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 0.6 GO:0061354 planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.2 31.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.8 GO:1903487 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) regulation of lactation(GO:1903487)
0.2 1.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 0.8 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 4.4 GO:0051923 sulfation(GO:0051923)
0.2 1.6 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.2 2.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 2.4 GO:0007343 egg activation(GO:0007343)
0.2 2.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.1 0.4 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.4 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.1 33.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.7 GO:0035546 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 2.9 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.5 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.8 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 3.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.4 GO:0060157 urinary bladder development(GO:0060157)
0.1 1.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 3.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.3 GO:0009437 carnitine metabolic process(GO:0009437) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.3 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.9 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.1 0.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.9 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.3 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.5 GO:0015671 oxygen transport(GO:0015671)
0.1 1.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.6 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.2 GO:0046356 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.1 0.2 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.5 GO:0030242 pexophagy(GO:0030242)
0.0 0.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 4.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 2.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.3 GO:0032202 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.0 0.9 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 4.2 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.6 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0006907 pinocytosis(GO:0006907)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.5 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.8 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.8 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 1.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.6 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 5.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.6 8.6 GO:0031983 vesicle lumen(GO:0031983)
0.4 4.0 GO:0019815 B cell receptor complex(GO:0019815)
0.3 31.6 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.2 3.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.8 GO:0035101 FACT complex(GO:0035101)
0.2 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 1.1 GO:1990246 uniplex complex(GO:1990246)
0.2 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 2.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.9 GO:0036396 MIS complex(GO:0036396)
0.1 1.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.9 GO:0097422 extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 2.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0097444 spine apparatus(GO:0097444)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 4.4 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 1.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 2.0 GO:0030286 dynein complex(GO:0030286)
0.0 14.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 1.7 GO:0045178 basal part of cell(GO:0045178)
0.0 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 41.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 3.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.7 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.2 3.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.9 2.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.6 4.4 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.6 1.7 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 2.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.4 1.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 1.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.4 1.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.4 2.1 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.4 1.1 GO:0015292 uniporter activity(GO:0015292)
0.4 1.5 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.3 2.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 3.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 2.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 8.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 35.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.7 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.7 GO:0045142 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.2 1.6 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.2 0.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 0.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 4.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 1.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 2.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.5 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 2.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.5 GO:0004904 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.1 4.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 2.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 4.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 2.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.9 GO:0015293 symporter activity(GO:0015293)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 ST GAQ PATHWAY G alpha q Pathway
0.1 4.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 11.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 8.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 2.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 5.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 2.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 5.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 3.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis