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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Cxxc1

Z-value: 0.37

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Transcription factors associated with Cxxc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024560.8 Cxxc1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cxxc1mm39_v1_chr18_+_74349189_743492170.019.4e-01Click!

Activity profile of Cxxc1 motif

Sorted Z-values of Cxxc1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Cxxc1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_135287372 2.80 ENSMUST00000050471.4
phosphatidylethanolamine binding protein 2
chr7_-_45546081 1.85 ENSMUST00000120299.4
ENSMUST00000039049.16
synaptogyrin 4
chr5_+_14075281 1.81 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr3_-_146205429 1.67 ENSMUST00000029839.11
spermatogenesis associated 1
chr8_+_93084253 1.63 ENSMUST00000210246.2
ENSMUST00000034184.12
Iroquois homeobox 5
chr13_-_55979191 1.57 ENSMUST00000021968.7
paired-like homeodomain transcription factor 1
chr5_+_25721059 1.51 ENSMUST00000045016.9
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr1_+_86354045 1.35 ENSMUST00000046004.6
testis expressed 44
chr4_-_42853888 1.02 ENSMUST00000107979.2
family with sequence similarity 205, member A1
chr10_+_75790348 0.92 ENSMUST00000099577.4
predicted gene 5134
chr5_-_25305621 0.87 ENSMUST00000030784.14
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_+_78016468 0.86 ENSMUST00000118869.8
ENSMUST00000125615.2
ciliogenesis associated kinase 1
chrX_+_5959507 0.79 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr7_-_126944754 0.77 ENSMUST00000205266.2
zinc finger protein 768
chr3_-_41696906 0.72 ENSMUST00000026866.15
sodium channel and clathrin linker 1
chr7_-_129867967 0.67 ENSMUST00000117872.8
ENSMUST00000120187.9
fibroblast growth factor receptor 2
chr9_+_64940004 0.66 ENSMUST00000167773.2
dipeptidylpeptidase 8
chr18_-_43610829 0.62 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr7_-_129867921 0.61 ENSMUST00000122054.8
fibroblast growth factor receptor 2
chr4_+_108857803 0.60 ENSMUST00000065977.11
ENSMUST00000102736.9
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr19_-_4489415 0.60 ENSMUST00000235680.2
ENSMUST00000117462.2
ENSMUST00000048197.10
ras homolog family member D
chr16_-_64591509 0.58 ENSMUST00000076991.7
RIKEN cDNA 4930453N24 gene
chr4_+_108857967 0.58 ENSMUST00000106644.9
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr7_-_28135616 0.48 ENSMUST00000208199.2
sterile alpha motif domain containing 4B
chr9_-_107483855 0.43 ENSMUST00000073448.12
ENSMUST00000194606.2
ENSMUST00000195662.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_+_128346655 0.39 ENSMUST00000042942.10
Sec23 interacting protein
chr1_+_59296065 0.33 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr10_-_51507527 0.32 ENSMUST00000219286.2
ENSMUST00000020062.4
ENSMUST00000218684.2
G protein-coupled receptor, family C, group 6, member A
chr11_-_88608958 0.30 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr11_+_113540154 0.29 ENSMUST00000063776.14
component of oligomeric golgi complex 1
chr17_+_28076209 0.28 ENSMUST00000130810.2
UHRF1 (ICBP90) binding protein 1
chr14_-_62718581 0.27 ENSMUST00000186010.8
predicted gene 4131
chr17_-_87754282 0.25 ENSMUST00000234406.2
ENSMUST00000040440.7
calmodulin 2
chr17_-_56343531 0.24 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr11_+_113539995 0.19 ENSMUST00000018805.15
component of oligomeric golgi complex 1
chr19_+_38919477 0.18 ENSMUST00000145051.2
helicase, lymphoid specific
chr18_+_37138256 0.17 ENSMUST00000115658.6
protocadherin alpha 11
chr10_-_78248771 0.15 ENSMUST00000062678.11
ribosomal RNA processing 1
chr11_-_85125889 0.13 ENSMUST00000018625.10
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr2_+_151753119 0.09 ENSMUST00000028955.6
angiopoietin 4
chr15_-_38518406 0.05 ENSMUST00000151319.8
antizyme inhibitor 1
chr11_+_60428788 0.02 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr9_-_78016302 0.01 ENSMUST00000001402.14
f-box protein 9
chr2_+_146854916 0.00 ENSMUST00000028921.6
5'-3' exoribonuclease 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.4 1.6 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.5 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 1.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.8 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.9 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 1.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.8 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors