ISMARA results: E2f1

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for E2f1

Z-value: 4.01

Motif logo

Transcription factors associated with E2f1

Gene Symbol	Gene ID	Gene Info
E2f1 Ensembl NCBI MGI UniProt	ENSMUSG00000027490.18	E2f1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2f1	mm39_v1_chr2_-_154411765_154411812	0.56	2.5e-07	Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_+_56610396 Show fit	31.75	ENSMUST00000113038.8	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr18_+_56840813 Show fit	29.01	ENSMUST00000025486.9	Lmnb1 Ensembl NCBI MGI UniProt Show fit	lamin B1
chr7_+_102090892 Show fit	28.50	ENSMUST00000033283.10	Rrm1 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M1
chr5_+_45827249 Show fit	28.41	ENSMUST00000117396.3	Ncapg Ensembl NCBI MGI UniProt Show fit	non-SMC condensin I complex, subunit G
chr6_-_47571901 Show fit	28.33	ENSMUST00000081721.13 ENSMUST00000114618.8 ENSMUST00000114616.8	Ezh2 Ensembl NCBI MGI UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_+_65797519 Show fit	28.26	ENSMUST00000045802.7	Pclaf Ensembl NCBI MGI UniProt Show fit	PCNA clamp associated factor
chr17_+_56610321 Show fit	25.93	ENSMUST00000001258.15	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr1_-_20890437 Show fit	24.14	ENSMUST00000053266.11	Mcm3 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 3
chr17_+_29709723 Show fit	23.57	ENSMUST00000024811.9	Pim1 Ensembl NCBI MGI UniProt Show fit	proviral integration site 1
chr16_+_93680783 Show fit	23.37	ENSMUST00000023666.11 ENSMUST00000117099.8	Chaf1b Ensembl NCBI MGI UniProt Show fit	chromatin assembly factor 1, subunit B (p60)
chr10_-_128540847 Show fit	22.96	ENSMUST00000026415.9 ENSMUST00000026416.15	Cdk2 Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 2
chr14_-_47514248 Show fit	22.05	ENSMUST00000187531.8 ENSMUST00000111790.2	Wdhd1 Ensembl NCBI MGI UniProt Show fit	WD repeat and HMG-box DNA binding protein 1
chr4_-_59549314 Show fit	20.18	ENSMUST00000148331.9 ENSMUST00000030076.12	Ptbp3 Ensembl NCBI MGI UniProt Show fit	polypyrimidine tract binding protein 3
chr8_+_57964956 Show fit	20.05	ENSMUST00000210871.2	Hmgb2 Ensembl NCBI MGI UniProt Show fit	high mobility group box 2
chr2_+_78699360 Show fit	19.52	ENSMUST00000028398.14	Ube2e3 Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2E 3
chr12_+_69215583 Show fit	19.48	ENSMUST00000110621.3 ENSMUST00000222520.2	Lrr1 Ensembl NCBI MGI UniProt Show fit	leucine rich repeat protein 1
chr4_+_131600918 Show fit	19.27	ENSMUST00000053819.6	Srsf4 Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 4
chr1_-_74544946 Show fit	18.95	ENSMUST00000044260.11 ENSMUST00000186282.7	Usp37 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 37
chr10_-_21036792 Show fit	18.94	ENSMUST00000188495.8	Myb Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene
chr9_-_61854050 Show fit	18.40	ENSMUST00000034815.9	Kif23 Ensembl NCBI MGI UniProt Show fit	kinesin family member 23
chr2_+_72306503 Show fit	17.52	ENSMUST00000102691.11 ENSMUST00000157019.2	Cdca7 Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 7
chr14_-_79539063 Show fit	17.46	ENSMUST00000022595.8	Rgcc Ensembl NCBI MGI UniProt Show fit	regulator of cell cycle
chr4_-_133695204 Show fit	17.40	ENSMUST00000100472.10 ENSMUST00000136327.2	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr10_-_21036824 Show fit	17.30	ENSMUST00000020158.9	Myb Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene
chr4_-_59549243 Show fit	17.25	ENSMUST00000173699.8 ENSMUST00000173884.8 ENSMUST00000102883.11 ENSMUST00000174586.8	Ptbp3 Ensembl NCBI MGI UniProt Show fit	polypyrimidine tract binding protein 3
chr4_+_24496434 Show fit	17.19	ENSMUST00000108222.9 ENSMUST00000138567.9 ENSMUST00000050446.13	Mms22l Ensembl NCBI MGI UniProt Show fit	MMS22-like, DNA repair protein
chr1_+_74545203 Show fit	16.96	ENSMUST00000087215.7	Cnot9 Ensembl NCBI MGI UniProt Show fit	CCR4-NOT transcription complex, subunit 9
chr13_-_100912308 Show fit	16.83	ENSMUST00000075550.4	Cenph Ensembl NCBI MGI UniProt Show fit	centromere protein H
chr13_-_55477535 Show fit	15.93	ENSMUST00000021941.8	Mxd3 Ensembl NCBI MGI UniProt Show fit	Max dimerization protein 3
chrX_-_50294652 Show fit	15.50	ENSMUST00000114875.8	Mbnl3 Ensembl NCBI MGI UniProt Show fit	muscleblind like splicing factor 3
chr7_-_126625657 Show fit	15.44	ENSMUST00000205568.2	Maz Ensembl NCBI MGI UniProt Show fit	MYC-associated zinc finger protein (purine-binding transcription factor)
chr15_-_57998443 Show fit	15.20	ENSMUST00000038194.5	Atad2 Ensembl NCBI MGI UniProt Show fit	ATPase family, AAA domain containing 2
chr4_+_11191726 Show fit	14.83	ENSMUST00000029866.16 ENSMUST00000108324.4	Ccne2 Ensembl NCBI MGI UniProt Show fit	cyclin E2
chr12_+_116369017 Show fit	14.78	ENSMUST00000084828.5 ENSMUST00000222469.2 ENSMUST00000221114.2 ENSMUST00000221970.2	Ncapg2 Ensembl NCBI MGI UniProt Show fit	non-SMC condensin II complex, subunit G2
chr5_-_138169509 Show fit	14.68	ENSMUST00000153867.8	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr8_+_71858647 Show fit	14.65	ENSMUST00000119976.8 ENSMUST00000120725.2	Ankle1 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and LEM domain containing 1
chr4_-_46404224 Show fit	14.60	ENSMUST00000107764.9	Hemgn Ensembl NCBI MGI UniProt Show fit	hemogen
chr4_+_52439237 Show fit	14.37	ENSMUST00000102915.10 ENSMUST00000117280.8 ENSMUST00000142227.3	Smc2 Ensembl NCBI MGI UniProt Show fit	structural maintenance of chromosomes 2
chr17_+_36176948 Show fit	14.24	ENSMUST00000122899.8	Ppp1r18 Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 18
chr11_+_98798627 Show fit	14.10	ENSMUST00000092706.13	Cdc6 Ensembl NCBI MGI UniProt Show fit	cell division cycle 6
chr5_+_65921414 Show fit	13.89	ENSMUST00000201615.4 ENSMUST00000087264.4	N4bp2 Ensembl NCBI MGI UniProt Show fit	NEDD4 binding protein 2
chr8_-_84831391 Show fit	13.86	ENSMUST00000041367.9 ENSMUST00000210279.2	Dcaf15 Ensembl NCBI MGI UniProt Show fit	DDB1 and CUL4 associated factor 15
chr4_+_126450728 Show fit	13.68	ENSMUST00000048391.15	Clspn Ensembl NCBI MGI UniProt Show fit	claspin
chr17_-_35827676 Show fit	13.53	ENSMUST00000160885.2 ENSMUST00000159009.2 ENSMUST00000161012.8	Tcf19 Ensembl NCBI MGI UniProt Show fit	transcription factor 19
chr17_+_36152383 Show fit	13.35	ENSMUST00000082337.13	Mdc1 Ensembl NCBI MGI UniProt Show fit	mediator of DNA damage checkpoint 1
chr5_+_114912738 Show fit	13.27	ENSMUST00000102578.11	Ankrd13a Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 13a
chr2_+_162896602 Show fit	13.23	ENSMUST00000018005.10	Mybl2 Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene-like 2
chr1_-_191307648 Show fit	13.07	ENSMUST00000027933.11	Dtl Ensembl NCBI MGI UniProt Show fit	denticleless E3 ubiquitin protein ligase
chr4_+_114857348 Show fit	12.85	ENSMUST00000030490.13	Stil Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chr15_+_102379621 Show fit	12.82	ENSMUST00000229918.2	Pcbp2 Ensembl NCBI MGI UniProt Show fit	poly(rC) binding protein 2
chr15_+_55420795 Show fit	12.79	ENSMUST00000022998.14	Mtbp Ensembl NCBI MGI UniProt Show fit	Mdm2, transformed 3T3 cell double minute p53 binding protein
chr8_+_75836187 Show fit	12.68	ENSMUST00000164309.3 ENSMUST00000212426.2 ENSMUST00000212811.2	Mcm5 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 5
chrX_+_70600481 Show fit	12.67	ENSMUST00000123100.2	Hmgb3 Ensembl NCBI MGI UniProt Show fit	high mobility group box 3
chr14_-_47514308 Show fit	12.37	ENSMUST00000111792.9	Wdhd1 Ensembl NCBI MGI UniProt Show fit	WD repeat and HMG-box DNA binding protein 1
chr6_-_126916487 Show fit	12.35	ENSMUST00000144954.5 ENSMUST00000112220.8 ENSMUST00000112221.8	Rad51ap1 Ensembl NCBI MGI UniProt Show fit	RAD51 associated protein 1
chr7_-_126625739 Show fit	12.29	ENSMUST00000205461.2	Maz Ensembl NCBI MGI UniProt Show fit	MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_+_13012735 Show fit	12.17	ENSMUST00000098814.13 ENSMUST00000146998.9	Lig1 Ensembl NCBI MGI UniProt Show fit	ligase I, DNA, ATP-dependent
chr8_+_13388745 Show fit	12.11	ENSMUST00000209885.2 ENSMUST00000209396.2	Tfdp1 Ensembl NCBI MGI UniProt Show fit	transcription factor Dp 1
chr17_-_71833752 Show fit	12.09	ENSMUST00000232863.2 ENSMUST00000024851.10	Ndc80 Ensembl NCBI MGI UniProt Show fit	NDC80 kinetochore complex component
chr17_+_56611313 Show fit	12.07	ENSMUST00000113035.8 ENSMUST00000113039.9 ENSMUST00000142387.2	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chrX_-_50294867 Show fit	12.07	ENSMUST00000114876.9	Mbnl3 Ensembl NCBI MGI UniProt Show fit	muscleblind like splicing factor 3
chr3_-_19365431 Show fit	11.96	ENSMUST00000099195.10	Pde7a Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 7A
chr4_-_133695264 Show fit	11.95	ENSMUST00000102553.11	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr12_+_24758240 Show fit	11.94	ENSMUST00000020980.12	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr15_+_102379503 Show fit	11.94	ENSMUST00000229222.2	Pcbp2 Ensembl NCBI MGI UniProt Show fit	poly(rC) binding protein 2
chr8_-_79235505 Show fit	11.73	ENSMUST00000211719.2 ENSMUST00000049245.10	Rbmxl1 Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein, X-linked like-1
chr17_-_57137898 Show fit	11.72	ENSMUST00000233000.2 ENSMUST00000002444.15 ENSMUST00000086801.7	Rfx2 Ensembl NCBI MGI UniProt Show fit	regulatory factor X, 2 (influences HLA class II expression)
chr10_+_79852487 Show fit	11.48	ENSMUST00000099501.10	Arhgap45 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 45
chr2_-_65955338 Show fit	11.45	ENSMUST00000028378.4	Galnt3 Ensembl NCBI MGI UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 3
chr10_+_79852750 Show fit	11.23	ENSMUST00000105373.8	Arhgap45 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 45
chr5_-_138169253 Show fit	11.11	ENSMUST00000139983.8	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr12_+_24758724 Show fit	11.05	ENSMUST00000153058.8	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr7_-_28071658 Show fit	11.02	ENSMUST00000094644.11	Plekhg2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_181669891 Show fit	11.02	ENSMUST00000193028.2 ENSMUST00000191878.6 ENSMUST00000005003.12	Lbr Ensembl NCBI MGI UniProt Show fit	lamin B receptor
chr19_+_38919353 Show fit	10.98	ENSMUST00000025965.12	Hells Ensembl NCBI MGI UniProt Show fit	helicase, lymphoid specific
chr1_-_55401851 Show fit	10.96	ENSMUST00000114423.7	Boll Ensembl NCBI MGI UniProt Show fit	boule homolog, RNA binding protein
chr8_-_84769170 Show fit	10.93	ENSMUST00000005601.9	Il27ra Ensembl NCBI MGI UniProt Show fit	interleukin 27 receptor, alpha
chr7_-_126817639 Show fit	10.93	ENSMUST00000152267.8 ENSMUST00000106314.8	Septin1 Ensembl NCBI MGI UniProt Show fit	septin 1
chr11_+_118913788 Show fit	10.79	ENSMUST00000026662.8	Cbx2 Ensembl NCBI MGI UniProt Show fit	chromobox 2
chr4_-_133694607 Show fit	10.73	ENSMUST00000105893.8	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr7_-_89630141 Show fit	10.68	ENSMUST00000238981.2 ENSMUST00000208977.2 ENSMUST00000107234.3	Eed Ensembl NCBI MGI UniProt Show fit	embryonic ectoderm development
chr2_-_60213639 Show fit	10.61	ENSMUST00000112533.8	Ly75 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 75
chr5_-_138170077 Show fit	10.53	ENSMUST00000155902.8 ENSMUST00000148879.8	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr8_+_47070326 Show fit	10.51	ENSMUST00000211115.2 ENSMUST00000093517.7	Casp3 Ensembl NCBI MGI UniProt Show fit	caspase 3
chr15_+_61857226 Show fit	10.50	ENSMUST00000161976.8 ENSMUST00000022971.8	Myc Ensembl NCBI MGI UniProt Show fit	myelocytomatosis oncogene
chr11_-_75918551 Show fit	10.49	ENSMUST00000021207.7	Rflnb Ensembl NCBI MGI UniProt Show fit	refilin B
chr7_+_25386418 Show fit	10.48	ENSMUST00000002678.10	Tgfb1 Ensembl NCBI MGI UniProt Show fit	transforming growth factor, beta 1
chr19_-_5713701 Show fit	10.45	ENSMUST00000164304.9 ENSMUST00000237544.2	Sipa1 Ensembl NCBI MGI UniProt Show fit	signal-induced proliferation associated gene 1
chr5_+_107112186 Show fit	10.43	ENSMUST00000117196.9 ENSMUST00000031221.12 ENSMUST00000076467.13	Cdc7 Ensembl NCBI MGI UniProt Show fit	cell division cycle 7 (S. cerevisiae)
chr15_+_61857390 Show fit	10.39	ENSMUST00000159327.2 ENSMUST00000167731.8	Myc Ensembl NCBI MGI UniProt Show fit	myelocytomatosis oncogene
chr6_-_91093766 Show fit	10.38	ENSMUST00000113509.2 ENSMUST00000032179.14	Nup210 Ensembl NCBI MGI UniProt Show fit	nucleoporin 210
chr4_-_144973423 Show fit	10.36	ENSMUST00000030336.11	Tnfrsf1b Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 1b
chr9_+_21437440 Show fit	10.33	ENSMUST00000086361.12 ENSMUST00000173769.3	AB124611 Ensembl NCBI MGI UniProt Show fit	cDNA sequence AB124611
chr14_+_30853010 Show fit	10.29	ENSMUST00000227096.2	Nt5dc2 Ensembl NCBI MGI UniProt Show fit	5'-nucleotidase domain containing 2
chr10_+_110581293 Show fit	10.23	ENSMUST00000174857.8 ENSMUST00000073781.12 ENSMUST00000173471.8 ENSMUST00000173634.2	E2f7 Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 7
chr7_-_126817475 Show fit	10.20	ENSMUST00000106313.8 ENSMUST00000142356.3	Septin1 Ensembl NCBI MGI UniProt Show fit	septin 1
chr11_+_85202058 Show fit	10.16	ENSMUST00000020835.16	Ppm1d Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1D magnesium-dependent, delta isoform
chr19_-_5713648 Show fit	10.16	ENSMUST00000080824.13 ENSMUST00000237874.2 ENSMUST00000071857.13 ENSMUST00000236464.2	Sipa1 Ensembl NCBI MGI UniProt Show fit	signal-induced proliferation associated gene 1
chr4_+_108436639 Show fit	10.09	ENSMUST00000102744.4	Orc1 Ensembl NCBI MGI UniProt Show fit	origin recognition complex, subunit 1
chr4_-_133694543 Show fit	10.07	ENSMUST00000123234.8	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr17_+_88282472 Show fit	10.05	ENSMUST00000005503.5	Msh6 Ensembl NCBI MGI UniProt Show fit	mutS homolog 6
chr2_-_157046386 Show fit	10.05	ENSMUST00000029170.8	Rbl1 Ensembl NCBI MGI UniProt Show fit	RB transcriptional corepressor like 1
chr2_+_51962831 Show fit	9.96	ENSMUST00000112693.10	Rif1 Ensembl NCBI MGI UniProt Show fit	replication timing regulatory factor 1
chr12_+_24758968 Show fit	9.95	ENSMUST00000154588.2	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr7_-_101899294 Show fit	9.87	ENSMUST00000106923.2 ENSMUST00000098230.11	Rhog Ensembl NCBI MGI UniProt Show fit	ras homolog family member G
chr1_-_180641430 Show fit	9.75	ENSMUST00000162814.8	H3f3a Ensembl NCBI MGI UniProt Show fit	H3.3 histone A
chr19_+_8919228 Show fit	9.74	ENSMUST00000096240.3	Mta2 Ensembl NCBI MGI UniProt Show fit	metastasis-associated gene family, member 2
chr8_-_33875498 Show fit	9.72	ENSMUST00000033990.7 ENSMUST00000033991.13	Wrn Ensembl NCBI MGI UniProt Show fit	Werner syndrome RecQ like helicase
chr13_-_23945189 Show fit	9.69	ENSMUST00000102964.4	H4c1 Ensembl NCBI MGI UniProt Show fit	H4 clustered histone 1
chr14_-_54791816 Show fit	9.54	ENSMUST00000022784.9	Haus4 Ensembl NCBI MGI UniProt Show fit	HAUS augmin-like complex, subunit 4
chr3_+_40754448 Show fit	9.52	ENSMUST00000026858.11	Plk4 Ensembl NCBI MGI UniProt Show fit	polo like kinase 4
chr8_-_54091980 Show fit	9.52	ENSMUST00000047768.11	Neil3 Ensembl NCBI MGI UniProt Show fit	nei like 3 (E. coli)
chr9_+_13246536 Show fit	9.48	ENSMUST00000217444.4 ENSMUST00000110583.12 ENSMUST00000239561.1	Ccdc82 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 82
chr8_-_35962641 Show fit	9.40	ENSMUST00000033927.8	Eri1 Ensembl NCBI MGI UniProt Show fit	exoribonuclease 1
chr17_+_36152559 Show fit	9.39	ENSMUST00000174124.2	Mdc1 Ensembl NCBI MGI UniProt Show fit	mediator of DNA damage checkpoint 1
chr8_+_47070461 Show fit	9.35	ENSMUST00000210534.2	Casp3 Ensembl NCBI MGI UniProt Show fit	caspase 3
chr18_+_4921663 Show fit	9.35	ENSMUST00000143254.8	Svil Ensembl NCBI MGI UniProt Show fit	supervillin
chr1_+_151447124 Show fit	9.34	ENSMUST00000148810.8	Niban1 Ensembl NCBI MGI UniProt Show fit	niban apoptosis regulator 1
chr13_+_73615316 Show fit	9.34	ENSMUST00000022099.15	Lpcat1 Ensembl NCBI MGI UniProt Show fit	lysophosphatidylcholine acyltransferase 1
chr4_+_108316568 Show fit	9.33	ENSMUST00000106673.8 ENSMUST00000043368.12	Tut4 Ensembl NCBI MGI UniProt Show fit	terminal uridylyl transferase 4
chr16_-_18630365 Show fit	9.26	ENSMUST00000096990.10	Cdc45 Ensembl NCBI MGI UniProt Show fit	cell division cycle 45
chr6_-_125262974 Show fit	9.25	ENSMUST00000088246.6	Tuba3a Ensembl NCBI MGI UniProt Show fit	tubulin, alpha 3A
chr2_+_71617266 Show fit	9.25	ENSMUST00000112101.8 ENSMUST00000028522.10	Itga6 Ensembl NCBI MGI UniProt Show fit	integrin alpha 6
chr10_+_39608094 Show fit	9.22	ENSMUST00000019986.13	Rev3l Ensembl NCBI MGI UniProt Show fit	REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_+_190795198 Show fit	9.19	ENSMUST00000076952.12 ENSMUST00000139340.8 ENSMUST00000078259.8	Nsl1 Ensembl NCBI MGI UniProt Show fit	NSL1, MIS12 kinetochore complex component
chr5_-_151574620 Show fit	9.19	ENSMUST00000038131.10	Rfc3 Ensembl NCBI MGI UniProt Show fit	replication factor C (activator 1) 3
chr10_+_96452860 Show fit	9.17	ENSMUST00000038377.9	Btg1 Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 1
chr19_-_10181243 Show fit	9.14	ENSMUST00000142241.2 ENSMUST00000116542.9 ENSMUST00000025651.6 ENSMUST00000156291.2	Fen1 Ensembl NCBI MGI UniProt Show fit	flap structure specific endonuclease 1
chr10_+_127851031 Show fit	9.13	ENSMUST00000178041.8 ENSMUST00000026461.8	Prim1 Ensembl NCBI MGI UniProt Show fit	DNA primase, p49 subunit
chr7_-_89629809 Show fit	9.10	ENSMUST00000238792.2	Eed Ensembl NCBI MGI UniProt Show fit	embryonic ectoderm development
chr3_+_40754489 Show fit	9.10	ENSMUST00000203295.3	Plk4 Ensembl NCBI MGI UniProt Show fit	polo like kinase 4
chr1_-_64776890 Show fit	9.09	ENSMUST00000116133.4 ENSMUST00000063982.7	Fzd5 Ensembl NCBI MGI UniProt Show fit	frizzled class receptor 5
chr4_+_11558905 Show fit	9.07	ENSMUST00000095145.12 ENSMUST00000108306.9 ENSMUST00000070755.13	Rad54b Ensembl NCBI MGI UniProt Show fit	RAD54 homolog B (S. cerevisiae)
chr8_+_85598734 Show fit	9.06	ENSMUST00000170296.2 ENSMUST00000136026.8	Syce2 Ensembl NCBI MGI UniProt Show fit	synaptonemal complex central element protein 2
chr4_-_115980813 Show fit	9.04	ENSMUST00000102704.4 ENSMUST00000102705.10	Rad54l Ensembl NCBI MGI UniProt Show fit	RAD54 like (S. cerevisiae)
chr1_-_128287347 Show fit	9.04	ENSMUST00000190495.2 ENSMUST00000027601.11	Mcm6 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 6
chr1_-_55402478 Show fit	9.04	ENSMUST00000087585.10	Boll Ensembl NCBI MGI UniProt Show fit	boule homolog, RNA binding protein
chr5_-_65855199 Show fit	8.99	ENSMUST00000031104.7	Pds5a Ensembl NCBI MGI UniProt Show fit	PDS5 cohesin associated factor A
chr10_-_80269436 Show fit	8.99	ENSMUST00000105346.10 ENSMUST00000020377.13 ENSMUST00000105340.8 ENSMUST00000020379.13 ENSMUST00000105344.8 ENSMUST00000105342.8 ENSMUST00000105345.10 ENSMUST00000105343.8	Tcf3 Ensembl NCBI MGI UniProt Show fit	transcription factor 3
chr5_-_65855511 Show fit	8.98	ENSMUST00000201948.4	Pds5a Ensembl NCBI MGI UniProt Show fit	PDS5 cohesin associated factor A
chr11_-_34724458 Show fit	8.93	ENSMUST00000093191.3	Spdl1 Ensembl NCBI MGI UniProt Show fit	spindle apparatus coiled-coil protein 1
chr5_-_138170644 Show fit	8.90	ENSMUST00000000505.16	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr10_-_90918566 Show fit	8.90	ENSMUST00000162618.8 ENSMUST00000020157.13 ENSMUST00000160788.2	Apaf1 Ensembl NCBI MGI UniProt Show fit	apoptotic peptidase activating factor 1
chr14_-_73563212 Show fit	8.88	ENSMUST00000022701.7	Rb1 Ensembl NCBI MGI UniProt Show fit	RB transcriptional corepressor 1
chr7_-_44198157 Show fit	8.87	ENSMUST00000145956.2 ENSMUST00000049343.15	Pold1 Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), delta 1, catalytic subunit
chr2_+_121786444 Show fit	8.86	ENSMUST00000036647.13	Ctdspl2 Ensembl NCBI MGI UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_+_3715747 Show fit	8.85	ENSMUST00000014118.4	Mcemp1 Ensembl NCBI MGI UniProt Show fit	mast cell expressed membrane protein 1
chr11_-_79971750 Show fit	8.84	ENSMUST00000103233.10 ENSMUST00000061283.15	Crlf3 Ensembl NCBI MGI UniProt Show fit	cytokine receptor-like factor 3
chr11_-_106163753 Show fit	8.84	ENSMUST00000021052.16	Smarcd2 Ensembl NCBI MGI UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr8_-_25592001 Show fit	8.83	ENSMUST00000128715.8	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr7_-_141023902 Show fit	8.79	ENSMUST00000026580.12	Pidd1 Ensembl NCBI MGI UniProt Show fit	p53 induced death domain protein 1
chr15_-_78657640 Show fit	8.76	ENSMUST00000018313.6	Mfng Ensembl NCBI MGI UniProt Show fit	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_121786892 Show fit	8.75	ENSMUST00000110578.8	Ctdspl2 Ensembl NCBI MGI UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_-_48530777 Show fit	8.70	ENSMUST00000058745.15	E2f8 Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 8
chr4_+_134879807 Show fit	8.68	ENSMUST00000119564.2	Runx3 Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 3
chr11_-_101442663 Show fit	8.66	ENSMUST00000017290.11	Brca1 Ensembl NCBI MGI UniProt Show fit	breast cancer 1, early onset
chr16_-_15455141 Show fit	8.65	ENSMUST00000023353.4	Mcm4 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 4
chr2_+_125089110 Show fit	8.61	ENSMUST00000082122.14	Dut Ensembl NCBI MGI UniProt Show fit	deoxyuridine triphosphatase
chr19_+_38919477 Show fit	8.60	ENSMUST00000145051.2	Hells Ensembl NCBI MGI UniProt Show fit	helicase, lymphoid specific
chr5_-_143717970 Show fit	8.58	ENSMUST00000053287.6	Usp42 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 42
chr2_+_29780122 Show fit	8.54	ENSMUST00000113762.8 ENSMUST00000113765.8	Odf2 Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 2
chr7_-_28071919 Show fit	8.54	ENSMUST00000119990.8	Plekhg2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr18_+_11790409 Show fit	8.54	ENSMUST00000047322.8	Rbbp8 Ensembl NCBI MGI UniProt Show fit	retinoblastoma binding protein 8, endonuclease
chr19_-_9876815 Show fit	8.54	ENSMUST00000237147.2 ENSMUST00000025562.9	Incenp Ensembl NCBI MGI UniProt Show fit	inner centromere protein
chr1_+_180468895 Show fit	8.53	ENSMUST00000192725.6	Lin9 Ensembl NCBI MGI UniProt Show fit	lin-9 homolog (C. elegans)
chr15_+_102378966 Show fit	8.49	ENSMUST00000077037.13 ENSMUST00000229102.2 ENSMUST00000229618.2 ENSMUST00000229275.2 ENSMUST00000231089.2 ENSMUST00000229802.2 ENSMUST00000229854.2 ENSMUST00000108838.5	Pcbp2 Ensembl NCBI MGI UniProt Show fit	poly(rC) binding protein 2
chr4_+_98812082 Show fit	8.46	ENSMUST00000091358.11	Usp1 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 1
chr5_+_135216090 Show fit	8.43	ENSMUST00000002825.6	Baz1b Ensembl NCBI MGI UniProt Show fit	bromodomain adjacent to zinc finger domain, 1B
chr4_+_114857370 Show fit	8.42	ENSMUST00000129957.8	Stil Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chr2_+_119449192 Show fit	8.41	ENSMUST00000028771.8	Nusap1 Ensembl NCBI MGI UniProt Show fit	nucleolar and spindle associated protein 1
chr4_-_40853950 Show fit	8.41	ENSMUST00000030121.13 ENSMUST00000108096.3	B4galt1 Ensembl NCBI MGI UniProt Show fit	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr5_-_8472582 Show fit	8.35	ENSMUST00000168500.8 ENSMUST00000002368.16	Dbf4 Ensembl NCBI MGI UniProt Show fit	DBF4 zinc finger
chr3_+_88439616 Show fit	8.35	ENSMUST00000172699.2	Mex3a Ensembl NCBI MGI UniProt Show fit	mex3 RNA binding family member A
chr13_-_47259266 Show fit	8.33	ENSMUST00000129352.3	Dek Ensembl NCBI MGI UniProt Show fit	DEK proto-oncogene (DNA binding)
chr1_+_86454431 Show fit	8.32	ENSMUST00000045897.15 ENSMUST00000186255.7 ENSMUST00000188699.7	Ptma Ensembl NCBI MGI UniProt Show fit	prothymosin alpha
chr16_+_36832119 Show fit	8.32	ENSMUST00000071452.12 ENSMUST00000054034.7	Polq Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), theta
chr2_-_60213575 Show fit	8.31	ENSMUST00000028362.9	Ly75 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 75
chrX_+_70599524 Show fit	8.30	ENSMUST00000072699.13 ENSMUST00000114582.9 ENSMUST00000015361.11 ENSMUST00000088874.10	Hmgb3 Ensembl NCBI MGI UniProt Show fit	high mobility group box 3
chr2_+_34999497 Show fit	8.26	ENSMUST00000028235.11 ENSMUST00000156933.8 ENSMUST00000028237.15 ENSMUST00000113032.8	Cntrl Ensembl NCBI MGI UniProt Show fit	centriolin
chr4_+_98812047 Show fit	8.25	ENSMUST00000030289.9	Usp1 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 1
chr19_-_5713728 Show fit	8.25	ENSMUST00000169854.2	Sipa1 Ensembl NCBI MGI UniProt Show fit	signal-induced proliferation associated gene 1
chrX_-_47543029 Show fit	8.24	ENSMUST00000114958.8	Elf4 Ensembl NCBI MGI UniProt Show fit	E74-like factor 4 (ets domain transcription factor)
chr17_-_29483075 Show fit	8.20	ENSMUST00000024802.10	Ppil1 Ensembl NCBI MGI UniProt Show fit	peptidylprolyl isomerase (cyclophilin)-like 1
chr7_-_48531344 Show fit	8.20	ENSMUST00000119223.2	E2f8 Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 8
chr17_+_28988354 Show fit	8.18	ENSMUST00000233109.2 ENSMUST00000004986.14	Mapk13 Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase 13
chr7_+_97102411 Show fit	8.16	ENSMUST00000121987.3 ENSMUST00000050732.14 ENSMUST00000205577.2 ENSMUST00000206279.2	Kctd14 Ensembl NCBI MGI UniProt Show fit	potassium channel tetramerisation domain containing 14
chr2_+_127967951 Show fit	8.13	ENSMUST00000089634.12 ENSMUST00000019281.14 ENSMUST00000110341.9 ENSMUST00000103211.8 ENSMUST00000103210.2	Bcl2l11 Ensembl NCBI MGI UniProt Show fit	BCL2-like 11 (apoptosis facilitator)
chr2_+_28730418 Show fit	8.13	ENSMUST00000113853.3	Ddx31 Ensembl NCBI MGI UniProt Show fit	DEAD/H box helicase 31
chr17_+_35827997 Show fit	8.12	ENSMUST00000164242.9 ENSMUST00000045956.14	Cchcr1 Ensembl NCBI MGI UniProt Show fit	coiled-coil alpha-helical rod protein 1
chr10_+_39608360 Show fit	8.12	ENSMUST00000164763.8	Rev3l Ensembl NCBI MGI UniProt Show fit	REV3 like, DNA directed polymerase zeta catalytic subunit
chr16_-_22946441 Show fit	8.09	ENSMUST00000133847.9 ENSMUST00000115338.8 ENSMUST00000023598.15	Rfc4 Ensembl NCBI MGI UniProt Show fit	replication factor C (activator 1) 4
chr5_-_105130522 Show fit	8.03	ENSMUST00000031239.13	Abcg3 Ensembl NCBI MGI UniProt Show fit	ATP binding cassette subfamily G member 3
chr15_-_77726333 Show fit	8.01	ENSMUST00000016771.13	Myh9 Ensembl NCBI MGI UniProt Show fit	myosin, heavy polypeptide 9, non-muscle
chr11_-_100986192 Show fit	8.01	ENSMUST00000019447.15	Psmc3ip Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr8_+_104977493 Show fit	7.97	ENSMUST00000034342.13 ENSMUST00000212433.2 ENSMUST00000211809.2	Cklf Ensembl NCBI MGI UniProt Show fit	chemokine-like factor
chr7_-_74204222 Show fit	7.88	ENSMUST00000134539.2 ENSMUST00000026897.14 ENSMUST00000098371.9	Slco3a1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 3a1
chr10_+_79690492 Show fit	7.87	ENSMUST00000171599.8 ENSMUST00000095457.11	Ptbp1 Ensembl NCBI MGI UniProt Show fit	polypyrimidine tract binding protein 1
chr9_-_36637670 Show fit	7.87	ENSMUST00000172702.9 ENSMUST00000172742.2	Chek1 Ensembl NCBI MGI UniProt Show fit	checkpoint kinase 1
chr2_+_71617402 Show fit	7.84	ENSMUST00000238991.2	Itga6 Ensembl NCBI MGI UniProt Show fit	integrin alpha 6
chr14_-_52257452 Show fit	7.84	ENSMUST00000228162.2	Zfp219 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 219

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.4	28.3	GO:0071707	immunoglobulin heavy chain V-D-J recombination(GO:0071707)
9.0	27.1	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
7.3	29.0	GO:0031660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
6.8	33.9	GO:0070829	heterochromatin maintenance(GO:0070829)
6.6	19.8	GO:0009955	adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011)
6.5	32.7	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
6.2	74.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
5.8	17.5	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
5.8	28.9	GO:0042631	cellular response to water deprivation(GO:0042631)
5.7	23.0	GO:0032298	positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
5.2	20.9	GO:0090095	lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
5.2	15.6	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
4.9	87.6	GO:0010216	maintenance of DNA methylation(GO:0010216)
4.7	23.3	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
4.6	69.4	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
4.6	18.4	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
4.4	69.6	GO:0019985	translesion synthesis(GO:0019985)
4.3	34.3	GO:0046601	positive regulation of centriole replication(GO:0046601)
4.3	25.7	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
4.1	16.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
4.0	43.7	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.9	23.4	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
3.7	11.2	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
3.7	7.4	GO:0002572	pro-T cell differentiation(GO:0002572)
3.5	21.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
3.5	80.0	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
3.4	10.1	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
3.3	36.7	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
3.3	3.3	GO:1905066	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
3.3	3.3	GO:2000424	regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
3.3	13.3	GO:0003017	lymph circulation(GO:0003017)
3.3	33.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
3.2	9.7	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
3.2	16.1	GO:1902340	telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
3.2	28.6	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
3.2	6.4	GO:1990918	double-strand break repair involved in meiotic recombination(GO:1990918)
3.1	27.7	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.0	21.3	GO:0000019	regulation of mitotic recombination(GO:0000019)
3.0	9.1	GO:0060061	Spemann organizer formation(GO:0060061)
3.0	57.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
3.0	77.6	GO:0006270	DNA replication initiation(GO:0006270)
3.0	8.9	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
3.0	8.9	GO:0045004	DNA replication proofreading(GO:0045004)
3.0	5.9	GO:0048627	myoblast development(GO:0048627)
2.9	11.7	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.8	17.0	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.8	22.3	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
2.7	8.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
2.7	29.8	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
2.7	5.4	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
2.7	16.1	GO:0033280	response to vitamin D(GO:0033280)
2.7	21.3	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
2.6	10.5	GO:1900158	negative regulation of bone mineralization involved in bone maturation(GO:1900158)
2.6	13.0	GO:1904976	response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.6	7.7	GO:0072757	cellular response to camptothecin(GO:0072757)
2.5	9.9	GO:0006203	dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
2.5	9.8	GO:1902363	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
2.5	27.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
2.5	4.9	GO:1904582	positive regulation of intracellular mRNA localization(GO:1904582)
2.4	2.4	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
2.4	19.3	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
2.3	9.3	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
2.3	6.9	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
2.3	50.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
2.2	15.7	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
2.2	6.7	GO:0045660	positive regulation of neutrophil differentiation(GO:0045660)
2.2	6.7	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
2.2	4.3	GO:0046060	dATP metabolic process(GO:0046060)
2.1	6.4	GO:2001076	negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
2.1	6.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
2.1	4.2	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
2.1	12.7	GO:0098535	de novo centriole assembly(GO:0098535)
2.1	37.4	GO:0043249	erythrocyte maturation(GO:0043249)
2.0	14.3	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
2.0	8.0	GO:1900756	protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
2.0	6.0	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
2.0	7.9	GO:0072355	histone H3-T3 phosphorylation(GO:0072355)
2.0	7.9	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.9	21.3	GO:0033504	floor plate development(GO:0033504)
1.9	5.8	GO:0060574	bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
1.9	5.7	GO:1990428	miRNA transport(GO:1990428)
1.9	1.9	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
1.9	9.3	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.9	5.6	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.8	53.9	GO:0040034	regulation of development, heterochronic(GO:0040034)
1.8	7.1	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.7	5.2	GO:2000813	negative regulation of barbed-end actin filament capping(GO:2000813)
1.7	12.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.7	5.1	GO:1905223	epicardium morphogenesis(GO:1905223)
1.7	1.7	GO:0010159	specification of organ position(GO:0010159)
1.7	5.1	GO:0000076	DNA replication checkpoint(GO:0000076)
1.7	16.7	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
1.7	6.7	GO:0015904	tetracycline transport(GO:0015904)
1.6	6.6	GO:2000410	peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) regulation of thymocyte migration(GO:2000410)
1.6	6.5	GO:0035822	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.6	9.7	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
1.6	9.7	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
1.6	9.5	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
1.6	12.6	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
1.5	7.7	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
1.5	6.1	GO:0051316	attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.5	3.1	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
1.5	6.1	GO:0051673	membrane disruption in other organism(GO:0051673)
1.5	28.7	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.5	4.5	GO:0032240	negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
1.5	4.4	GO:0002514	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.5	14.7	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
1.4	7.2	GO:0002835	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
1.4	8.4	GO:0042758	long-chain fatty acid catabolic process(GO:0042758)
1.4	4.1	GO:0032916	positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.4	6.8	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
1.3	9.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.3	5.2	GO:1902075	cellular response to salt(GO:1902075)
1.3	6.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
1.3	11.6	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.3	23.2	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
1.3	28.2	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
1.3	19.0	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
1.3	8.8	GO:0007527	adult somatic muscle development(GO:0007527)
1.2	15.0	GO:0035878	nail development(GO:0035878)
1.2	7.5	GO:0002326	B cell lineage commitment(GO:0002326)
1.2	6.2	GO:0003349	epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.2	1.2	GO:2000328	regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.2	8.5	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
1.2	2.4	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
1.2	3.6	GO:0019043	establishment of viral latency(GO:0019043)
1.2	2.4	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
1.2	24.8	GO:0030261	chromosome condensation(GO:0030261)
1.2	4.7	GO:1901003	negative regulation of fermentation(GO:1901003)
1.2	1.2	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.2	13.9	GO:0048251	elastic fiber assembly(GO:0048251)
1.2	3.5	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
1.1	3.4	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
1.1	2.3	GO:0060197	cloacal septation(GO:0060197)
1.1	4.6	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
1.1	13.6	GO:0036297	interstrand cross-link repair(GO:0036297)
1.1	2.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.1	7.6	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
1.1	3.2	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
1.1	16.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
1.1	33.1	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.1	20.1	GO:0008340	determination of adult lifespan(GO:0008340)
1.1	3.2	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
1.1	5.3	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.0	11.5	GO:0006353	DNA-templated transcription, termination(GO:0006353)
1.0	6.3	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.0	4.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
1.0	8.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.0	15.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
1.0	11.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
1.0	30.3	GO:0050779	RNA destabilization(GO:0050779)
1.0	6.8	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
1.0	2.9	GO:1903898	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.0	18.1	GO:0001675	acrosome assembly(GO:0001675)
1.0	8.6	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.9	2.8	GO:1901994	negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.9	3.8	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.9	3.8	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.9	9.3	GO:0060174	limb bud formation(GO:0060174)
0.9	3.7	GO:0061386	closure of optic fissure(GO:0061386)
0.9	16.7	GO:0034508	centromere complex assembly(GO:0034508)
0.9	22.2	GO:0031297	replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.9	5.5	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.9	1.8	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.9	7.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.9	6.3	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.9	6.3	GO:0051660	establishment of centrosome localization(GO:0051660)
0.9	2.7	GO:0021660	rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.9	1.8	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.9	7.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.9	3.5	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.9	8.8	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.9	2.6	GO:0060596	mammary placode formation(GO:0060596)
0.9	8.6	GO:0000729	DNA double-strand break processing(GO:0000729)
0.9	2.6	GO:0016584	nucleosome positioning(GO:0016584)
0.9	4.3	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.8	5.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.8	3.4	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.8	9.2	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.8	1.7	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.8	2.5	GO:0007403	glial cell fate determination(GO:0007403)
0.8	8.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.8	4.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.8	5.7	GO:1903232	melanosome assembly(GO:1903232)
0.8	1.6	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.8	2.4	GO:0009629	response to gravity(GO:0009629)
0.8	10.3	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.8	27.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.8	5.5	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.8	10.8	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.8	7.6	GO:0035372	protein localization to microtubule(GO:0035372)
0.7	1.5	GO:0060492	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.7	5.2	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.7	9.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7	8.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.7	2.2	GO:0060450	positive regulation of hindgut contraction(GO:0060450)
0.7	3.6	GO:0039019	pronephric nephron development(GO:0039019)
0.7	2.1	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.7	2.8	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7	4.2	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.7	3.5	GO:0006566	threonine metabolic process(GO:0006566)
0.7	2.8	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.7	6.2	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7	5.5	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.7	4.8	GO:0045585	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.7	4.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.7	3.4	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.7	8.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.7	3.3	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.7	5.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.7	3.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.7	5.2	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7	7.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6	2.6	GO:0050823	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.6	6.4	GO:0051026	chiasma assembly(GO:0051026)
0.6	4.5	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.6	27.4	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.6	3.2	GO:0071684	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.6	5.7	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.6	1.9	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.6	10.5	GO:0006855	drug transmembrane transport(GO:0006855)
0.6	6.1	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.6	7.3	GO:0006020	inositol metabolic process(GO:0006020)
0.6	8.4	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.6	4.8	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.6	1.8	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.6	1.8	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.6	5.4	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.6	10.1	GO:0006857	oligopeptide transport(GO:0006857)
0.6	5.9	GO:0015705	iodide transport(GO:0015705)
0.6	5.3	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.6	2.9	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6	4.1	GO:0097503	sialylation(GO:0097503)
0.6	3.4	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.6	6.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.6	2.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.6	10.7	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.6	11.7	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.6	9.9	GO:0006337	nucleosome disassembly(GO:0006337)
0.5	1.6	GO:0035038	female pronucleus assembly(GO:0035038)
0.5	2.2	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.5	6.5	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5	2.7	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.5	2.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.5	16.9	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.5	11.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5	6.8	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.5	3.6	GO:0014029	neural crest formation(GO:0014029)
0.5	2.6	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.5	1.6	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.5	3.1	GO:1990839	response to endothelin(GO:1990839)
0.5	1.6	GO:1904766	negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
0.5	2.1	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.5	2.6	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.5	3.1	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.5	2.5	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.5	2.0	GO:1902477	defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.5	7.6	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.5	4.5	GO:0060242	contact inhibition(GO:0060242)
0.5	1.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.5	1.5	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.5	2.0	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.5	13.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.5	2.9	GO:0042117	monocyte activation(GO:0042117)
0.5	6.3	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.5	1.9	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.5	3.8	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.5	4.7	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.5	0.5	GO:0072284	metanephric S-shaped body morphogenesis(GO:0072284)
0.5	1.4	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.5	6.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.5	2.8	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.5	5.1	GO:0016926	protein desumoylation(GO:0016926)
0.5	1.4	GO:0061090	positive regulation of sequestering of zinc ion(GO:0061090)
0.5	5.5	GO:0046599	regulation of centriole replication(GO:0046599)
0.5	0.9	GO:0072716	response to sorbitol(GO:0072708) response to actinomycin D(GO:0072716)
0.5	2.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5	24.9	GO:0006611	protein export from nucleus(GO:0006611)
0.5	5.9	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.4	7.2	GO:0072697	protein localization to cell cortex(GO:0072697)
0.4	2.2	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.4	4.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4	5.9	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.4	2.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.4	2.5	GO:0016266	O-glycan processing(GO:0016266)
0.4	1.7	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.4	8.7	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.4	4.1	GO:1990403	embryonic brain development(GO:1990403)
0.4	4.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.4	1.6	GO:2000657	regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.4	5.6	GO:0006824	cobalt ion transport(GO:0006824)
0.4	1.2	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.4	1.6	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4	17.5	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.4	13.9	GO:0071800	podosome assembly(GO:0071800)
0.4	2.3	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4	10.0	GO:0051310	metaphase plate congression(GO:0051310)
0.4	11.4	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.4	2.3	GO:0036337	Fas signaling pathway(GO:0036337)
0.4	5.6	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.4	3.3	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.4	2.6	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.4	1.8	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.4	2.6	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.4	5.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.4	2.9	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.4	33.7	GO:0051225	spindle assembly(GO:0051225)
0.4	3.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4	3.6	GO:0035608	protein deglutamylation(GO:0035608)
0.4	2.5	GO:0032202	telomere assembly(GO:0032202)
0.3	0.7	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.3	0.7	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.3	1.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.3	1.7	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.3	2.0	GO:0034334	adherens junction maintenance(GO:0034334)
0.3	10.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.3	1.6	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3	2.6	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.3	2.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.3	1.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3	4.4	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.3	1.9	GO:0014807	regulation of somitogenesis(GO:0014807)
0.3	8.7	GO:0043968	histone H2A acetylation(GO:0043968)
0.3	1.2	GO:0001777	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.3	1.8	GO:0006116	NADH oxidation(GO:0006116)
0.3	6.7	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.3	7.6	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.3	12.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.3	0.6	GO:0030043	actin filament fragmentation(GO:0030043)
0.3	17.5	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3	5.7	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.3	4.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.3	1.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3	10.6	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.3	2.2	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.3	3.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.3	19.0	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.3	3.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.3	0.5	GO:0031053	primary miRNA processing(GO:0031053)
0.3	2.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.3	8.3	GO:0006284	base-excision repair(GO:0006284)
0.3	0.3	GO:0019042	viral latency(GO:0019042) release from viral latency(GO:0019046)
0.3	4.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.3	4.2	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.3	6.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.3	10.8	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3	2.6	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.3	1.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.3	19.7	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.3	1.0	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.3	2.3	GO:0071896	protein localization to adherens junction(GO:0071896)
0.3	1.0	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2	1.5	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	2.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.2	2.6	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2	3.1	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.2	1.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	6.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	1.6	GO:0002051	osteoblast fate commitment(GO:0002051)
0.2	2.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2	0.5	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.2	2.3	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.2	4.7	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.2	0.9	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2	6.7	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	1.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.2	3.0	GO:0072189	ureter development(GO:0072189)
0.2	7.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	4.4	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.2	0.8	GO:0035549	interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.2	8.7	GO:0006334	nucleosome assembly(GO:0006334)
0.2	2.3	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	4.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2	1.0	GO:0097240	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2	2.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.2	2.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.2	0.6	GO:0040031	snRNA modification(GO:0040031)
0.2	1.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.2	1.8	GO:0006108	malate metabolic process(GO:0006108)
0.2	2.8	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.2	13.4	GO:0000819	sister chromatid segregation(GO:0000819)
0.2	3.7	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
0.2	1.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.2	1.9	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.2	1.9	GO:0051503	adenine nucleotide transport(GO:0051503)
0.2	2.3	GO:0061072	iris morphogenesis(GO:0061072)
0.2	1.9	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2	0.7	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2	4.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.2	1.3	GO:0090005	negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2	5.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2	2.0	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	0.5	GO:1902870	negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.2	13.0	GO:0007059	chromosome segregation(GO:0007059)
0.2	0.9	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2	5.6	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.2	2.8	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2	3.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.2	0.6	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2	2.7	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.2	1.7	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	1.6	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1	6.1	GO:0051028	mRNA transport(GO:0051028)
0.1	3.4	GO:0021535	cell migration in hindbrain(GO:0021535)
0.1	3.2	GO:0006907	pinocytosis(GO:0006907)
0.1	0.3	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1	1.2	GO:0070475	rRNA base methylation(GO:0070475)
0.1	1.4	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.1	7.4	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	5.1	GO:0048240	sperm capacitation(GO:0048240)
0.1	1.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	1.5	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.1	1.4	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1	0.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	5.0	GO:0002181	cytoplasmic translation(GO:0002181)
0.1	6.7	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	1.5	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.1	1.5	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1	0.8	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	3.0	GO:0044381	glucose import in response to insulin stimulus(GO:0044381)
0.1	0.1	GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1	2.4	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	1.9	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.1	3.4	GO:0006405	RNA export from nucleus(GO:0006405)
0.1	1.6	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	1.7	GO:0030903	notochord development(GO:0030903)
0.1	7.3	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.1	3.1	GO:0006783	heme biosynthetic process(GO:0006783)
0.1	1.8	GO:1903540	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1	0.9	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	2.4	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	23.8	GO:0006281	DNA repair(GO:0006281)
0.1	1.4	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	2.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	0.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	3.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	5.6	GO:0007566	embryo implantation(GO:0007566)
0.1	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.1	2.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.9	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.4	GO:0070417	cellular response to cold(GO:0070417)
0.1	7.3	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	1.0	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	10.2	GO:0000377	RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	0.3	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
0.1	1.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	1.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	3.0	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.8	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1	1.4	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	1.5	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.1	4.9	GO:0001541	ovarian follicle development(GO:0001541)
0.1	4.5	GO:0048144	fibroblast proliferation(GO:0048144)
0.1	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	5.4	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1	0.7	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	1.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	1.8	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1	2.2	GO:0016574	histone ubiquitination(GO:0016574)
0.1	4.8	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	1.5	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	2.8	GO:0006446	regulation of translational initiation(GO:0006446)
0.1	0.5	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.1	0.7	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	1.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	4.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	1.2	GO:0006465	signal peptide processing(GO:0006465)
0.1	1.9	GO:0031648	protein destabilization(GO:0031648)
0.1	1.5	GO:0034389	lipid particle organization(GO:0034389)
0.1	1.9	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	2.9	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.1	4.4	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.1	0.5	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	1.0	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.3	GO:1902414	protein localization to cell junction(GO:1902414)
0.1	1.1	GO:0008272	sulfate transport(GO:0008272)
0.1	4.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	1.0	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.6	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	6.4	GO:0043484	regulation of RNA splicing(GO:0043484)
0.1	1.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	0.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	1.4	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.9	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	6.4	GO:0030833	regulation of actin filament polymerization(GO:0030833)
0.0	1.5	GO:0018345	protein palmitoylation(GO:0018345)
0.0	3.8	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	1.9	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.6	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	2.4	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.0	0.5	GO:0097237	cellular response to toxic substance(GO:0097237)
0.0	2.7	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.7	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.3	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	1.7	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.0	0.1	GO:0015788	UDP-N-acetylglucosamine transport(GO:0015788)
0.0	0.6	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	2.0	GO:0007030	Golgi organization(GO:0007030)
0.0	1.5	GO:0050868	negative regulation of T cell activation(GO:0050868)
0.0	0.4	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.0	3.3	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.7	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.3	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.4	GO:0048701	embryonic cranial skeleton morphogenesis(GO:0048701)
0.0	1.0	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.7	GO:0006826	iron ion transport(GO:0006826)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.2	GO:0006517	protein deglycosylation(GO:0006517)
0.0	1.7	GO:0030217	T cell differentiation(GO:0030217)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	1.1	GO:0042113	B cell activation(GO:0042113)
0.0	0.2	GO:0051764	actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.1	45.2	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
10.2	61.4	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
9.1	36.3	GO:0033186	CAF-1 complex(GO:0033186)
7.9	126.5	GO:0042555	MCM complex(GO:0042555)
5.2	36.4	GO:0098536	deuterosome(GO:0098536)
5.0	30.2	GO:0005663	DNA replication factor C complex(GO:0005663)
4.7	56.8	GO:0000796	condensin complex(GO:0000796)
4.6	18.5	GO:0016035	zeta DNA polymerase complex(GO:0016035)
4.3	12.8	GO:1990423	RZZ complex(GO:1990423)
4.0	16.1	GO:0001740	Barr body(GO:0001740)
3.8	26.4	GO:0005638	lamin filament(GO:0005638)
3.2	38.0	GO:0001739	sex chromatin(GO:0001739)
3.1	9.3	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.1	18.4	GO:0097149	centralspindlin complex(GO:0097149)
3.0	12.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
3.0	24.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
2.6	10.3	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
2.6	2.6	GO:0097504	Gemini of coiled bodies(GO:0097504)
2.4	7.3	GO:0005673	transcription factor TFIIE complex(GO:0005673)
2.4	12.2	GO:0043293	apoptosome(GO:0043293)
2.3	16.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
2.3	22.7	GO:0042382	paraspeckles(GO:0042382)
2.2	13.2	GO:0031523	Myb complex(GO:0031523)
2.2	26.3	GO:0000801	central element(GO:0000801)
2.2	15.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.0	18.2	GO:0070652	HAUS complex(GO:0070652)
2.0	6.0	GO:0031261	GINS complex(GO:0000811) DNA replication preinitiation complex(GO:0031261)
2.0	21.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
2.0	9.8	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
2.0	11.7	GO:0044530	supraspliceosomal complex(GO:0044530)
1.9	23.2	GO:0031264	death-inducing signaling complex(GO:0031264)
1.8	123.8	GO:0005657	replication fork(GO:0005657)
1.8	14.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
1.8	10.7	GO:0033553	rDNA heterochromatin(GO:0033553)
1.8	8.9	GO:0035189	Rb-E2F complex(GO:0035189)
1.7	10.4	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
1.6	22.2	GO:0005688	U6 snRNP(GO:0005688)
1.6	50.1	GO:0045120	pronucleus(GO:0045120)
1.5	6.1	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
1.5	4.5	GO:0030905	retromer, tubulation complex(GO:0030905)
1.5	10.6	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.5	22.6	GO:0005652	nuclear lamina(GO:0005652)
1.5	2.9	GO:0071920	cleavage body(GO:0071920)
1.4	6.9	GO:0071953	elastic fiber(GO:0071953)
1.4	4.1	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
1.4	6.8	GO:0000938	GARP complex(GO:0000938)
1.2	3.7	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
1.2	18.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.1	13.8	GO:0005642	annulate lamellae(GO:0005642)
1.0	5.2	GO:0071797	LUBAC complex(GO:0071797)
1.0	9.4	GO:0045298	tubulin complex(GO:0045298)
1.0	3.1	GO:0070435	Shc-EGFR complex(GO:0070435)
1.0	30.0	GO:0005721	pericentric heterochromatin(GO:0005721)
1.0	8.2	GO:0001652	granular component(GO:0001652)
1.0	5.1	GO:0030896	checkpoint clamp complex(GO:0030896)
1.0	8.0	GO:0005826	actomyosin contractile ring(GO:0005826)
1.0	10.8	GO:0035102	PRC1 complex(GO:0035102)
1.0	4.8	GO:0017177	glucosidase II complex(GO:0017177)
0.9	17.8	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.9	9.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.9	6.3	GO:0044611	nuclear pore inner ring(GO:0044611)
0.9	9.0	GO:0000788	nuclear nucleosome(GO:0000788)
0.9	2.6	GO:1990879	CST complex(GO:1990879)
0.9	10.6	GO:0000974	Prp19 complex(GO:0000974)
0.9	6.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.8	3.4	GO:1990716	axonemal central apparatus(GO:1990716)
0.8	8.7	GO:0070531	BRCA1-A complex(GO:0070531)
0.8	11.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.8	14.0	GO:0097539	ciliary transition fiber(GO:0097539)
0.8	5.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8	5.4	GO:1990023	mitotic spindle midzone(GO:1990023)
0.8	3.0	GO:0030870	Mre11 complex(GO:0030870)
0.7	3.7	GO:0005667	transcription factor complex(GO:0005667)
0.7	8.0	GO:0070578	RISC-loading complex(GO:0070578)
0.7	5.8	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.7	4.3	GO:0097226	sperm mitochondrial sheath(GO:0097226)
0.7	9.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7	15.0	GO:0051233	spindle midzone(GO:0051233)
0.7	7.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.7	5.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7	6.7	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.7	8.0	GO:0031415	NatA complex(GO:0031415)
0.6	9.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.6	20.8	GO:0030056	hemidesmosome(GO:0030056)
0.6	7.5	GO:0034709	methylosome(GO:0034709)
0.6	8.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.6	38.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.6	25.4	GO:0090544	BAF-type complex(GO:0090544)
0.6	4.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.6	3.4	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.6	5.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.6	4.5	GO:0042825	TAP complex(GO:0042825)
0.6	5.0	GO:1990075	periciliary membrane compartment(GO:1990075)
0.5	3.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.5	0.5	GO:1903095	microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.5	2.1	GO:1990795	lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.5	1.6	GO:0036020	endolysosome membrane(GO:0036020)
0.5	5.7	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.5	4.0	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.5	5.0	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.5	2.0	GO:0071821	FANCM-MHF complex(GO:0071821)
0.5	2.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.5	3.9	GO:0070847	core mediator complex(GO:0070847)
0.5	4.3	GO:0045171	intercellular bridge(GO:0045171)
0.5	18.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.5	4.6	GO:0044666	MLL3/4 complex(GO:0044666)
0.5	9.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.4	2.7	GO:0070876	SOSS complex(GO:0070876)
0.4	7.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.4	8.8	GO:0070938	contractile ring(GO:0070938)
0.4	1.7	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.4	2.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.4	84.5	GO:0000775	chromosome, centromeric region(GO:0000775)
0.4	2.5	GO:0071547	piP-body(GO:0071547)
0.4	1.2	GO:0034457	Mpp10 complex(GO:0034457)
0.4	1.2	GO:0018444	translation release factor complex(GO:0018444)
0.4	1.2	GO:0031010	ISWI-type complex(GO:0031010)
0.4	6.8	GO:1904115	axon cytoplasm(GO:1904115)
0.4	42.5	GO:0016605	PML body(GO:0016605)
0.4	4.0	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.4	3.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.4	2.0	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.4	40.6	GO:0005814	centriole(GO:0005814)
0.4	4.6	GO:0034719	SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.4	0.8	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.4	6.1	GO:0042788	polysomal ribosome(GO:0042788)
0.4	10.4	GO:0043196	varicosity(GO:0043196)
0.4	3.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4	6.8	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4	3.2	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.3	5.6	GO:0031143	pseudopodium(GO:0031143)
0.3	5.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	7.3	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.3	22.1	GO:0005643	nuclear pore(GO:0005643)
0.3	4.1	GO:0044327	dendritic spine head(GO:0044327)
0.3	5.8	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3	10.3	GO:0097546	ciliary base(GO:0097546)
0.3	34.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.3	2.6	GO:0002177	manchette(GO:0002177)
0.3	12.0	GO:0005876	spindle microtubule(GO:0005876)
0.3	2.6	GO:0070187	telosome(GO:0070187)
0.3	2.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.3	2.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3	8.8	GO:0031528	microvillus membrane(GO:0031528)
0.3	5.8	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.3	15.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.3	7.0	GO:0035861	site of double-strand break(GO:0035861)
0.3	4.8	GO:0031083	BLOC-1 complex(GO:0031083)
0.3	4.7	GO:0000922	spindle pole(GO:0000922)
0.3	2.1	GO:0072687	meiotic spindle(GO:0072687)
0.3	2.9	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.3	1.4	GO:0000125	PCAF complex(GO:0000125)
0.3	236.9	GO:0005694	chromosome(GO:0005694)
0.3	4.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.3	17.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.3	3.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3	3.0	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.3	1.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3	6.9	GO:0000421	autophagosome membrane(GO:0000421)
0.3	2.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.3	10.8	GO:0002102	podosome(GO:0002102)
0.2	3.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	18.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.2	22.3	GO:0005581	collagen trimer(GO:0005581)
0.2	1.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	1.5	GO:0045179	apical cortex(GO:0045179)
0.2	22.8	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.2	5.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.2	1.0	GO:0097255	R2TP complex(GO:0097255)
0.2	0.6	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.2	2.0	GO:0061574	ASAP complex(GO:0061574)
0.2	0.8	GO:0042827	platelet dense granule(GO:0042827)
0.2	1.5	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2	8.5	GO:0005901	caveola(GO:0005901)
0.2	9.4	GO:0043034	costamere(GO:0043034)
0.2	1.9	GO:0071004	U2-type prespliceosome(GO:0071004)
0.2	6.1	GO:0030904	retromer complex(GO:0030904)
0.2	1.0	GO:0008091	spectrin(GO:0008091)
0.2	9.8	GO:0016363	nuclear matrix(GO:0016363)
0.2	1.6	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	1.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.2	12.8	GO:0005681	spliceosomal complex(GO:0005681)
0.2	1.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2	3.7	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	2.4	GO:0044294	dendritic growth cone(GO:0044294)
0.1	1.4	GO:0045495	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	4.0	GO:0002080	acrosomal membrane(GO:0002080)
0.1	11.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	2.7	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	34.2	GO:0016607	nuclear speck(GO:0016607)
0.1	3.8	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.1	6.4	GO:0009925	basal plasma membrane(GO:0009925)
0.1	3.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.6	GO:1990130	Iml1 complex(GO:1990130)
0.1	8.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	1.2	GO:0005787	signal peptidase complex(GO:0005787)
0.1	1.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	1.0	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	5.5	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	1.0	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.9	GO:0061689	tricellular tight junction(GO:0061689)
0.1	1.9	GO:0031519	PcG protein complex(GO:0031519)
0.1	6.8	GO:0031526	brush border membrane(GO:0031526)
0.1	0.8	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.8	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	6.3	GO:0032432	actin filament bundle(GO:0032432)
0.1	9.9	GO:0072562	blood microparticle(GO:0072562)
0.1	11.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.9	GO:0031932	TORC2 complex(GO:0031932)
0.1	19.1	GO:0016604	nuclear body(GO:0016604)
0.1	2.6	GO:0016235	aggresome(GO:0016235)
0.1	2.4	GO:0072686	mitotic spindle(GO:0072686)
0.1	1.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	9.5	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	5.1	GO:0000502	proteasome complex(GO:0000502)
0.1	29.1	GO:0005925	focal adhesion(GO:0005925)
0.1	5.9	GO:0005795	Golgi stack(GO:0005795)
0.1	30.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.5	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	2.3	GO:0005776	autophagosome(GO:0005776)
0.0	2.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	280.5	GO:0005634	nucleus(GO:0005634)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	5.0	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.3	GO:0032433	filopodium tip(GO:0032433)
0.0	0.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	1.0	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.9	GO:0036064	ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.9	76.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
10.2	61.4	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
9.1	9.1	GO:0015616	DNA translocase activity(GO:0015616)
7.2	36.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
6.6	19.9	GO:0003896	DNA primase activity(GO:0003896)
6.6	19.9	GO:0016005	phospholipase A2 activator activity(GO:0016005)
5.3	52.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
3.9	15.6	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
3.7	25.8	GO:0043515	kinetochore binding(GO:0043515)
3.6	14.3	GO:0071207	histone pre-mRNA stem-loop binding(GO:0071207)
3.3	10.0	GO:0004798	thymidylate kinase activity(GO:0004798)
3.2	9.7	GO:0061749	forked DNA-dependent helicase activity(GO:0061749) flap-structured DNA binding(GO:0070336)
3.2	18.9	GO:0010997	anaphase-promoting complex binding(GO:0010997)
3.1	9.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
3.0	9.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
2.9	32.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.9	8.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
2.8	8.5	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
2.8	8.4	GO:0004461	lactose synthase activity(GO:0004461)
2.8	8.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
2.7	38.5	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
2.7	8.1	GO:0042602	riboflavin reductase (NADPH) activity(GO:0042602)
2.6	7.9	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
2.5	15.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
2.5	15.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
2.4	7.3	GO:0031755	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
2.4	33.8	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
2.4	9.5	GO:0000405	bubble DNA binding(GO:0000405)
2.3	13.9	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.3	9.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
2.2	28.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
2.2	23.9	GO:0008494	translation activator activity(GO:0008494)
2.1	77.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
2.1	4.2	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)
2.1	10.6	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.0	10.2	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
2.0	20.1	GO:0050786	RAGE receptor binding(GO:0050786)
2.0	6.0	GO:0004418	hydroxymethylbilane synthase activity(GO:0004418)
1.9	5.7	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
1.8	19.7	GO:0070087	chromo shadow domain binding(GO:0070087)
1.7	10.5	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
1.7	15.5	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.7	17.1	GO:0038132	neuregulin binding(GO:0038132)
1.7	5.1	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
1.7	5.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.7	6.7	GO:0008493	tetracycline transporter activity(GO:0008493)
1.6	11.2	GO:1990715	mRNA CDS binding(GO:1990715)
1.6	12.7	GO:0003678	DNA helicase activity(GO:0003678)
1.6	12.6	GO:0061676	importin-alpha family protein binding(GO:0061676)
1.6	4.7	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
1.6	9.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.5	5.8	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.4	4.3	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.4	9.9	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
1.4	4.2	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.4	11.0	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
1.3	5.4	GO:0038025	reelin receptor activity(GO:0038025)
1.3	5.3	GO:0030519	snoRNP binding(GO:0030519)
1.3	6.4	GO:0030983	mismatched DNA binding(GO:0030983)
1.3	5.0	GO:0032357	guanine/thymine mispair binding(GO:0032137) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
1.3	12.5	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.2	6.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
1.2	7.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.2	7.3	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.2	10.9	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.2	4.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.2	7.0	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
1.2	43.1	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.2	16.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
1.1	4.5	GO:1990460	leptin receptor binding(GO:1990460)
1.1	9.0	GO:0070644	vitamin D response element binding(GO:0070644)
1.1	31.4	GO:0035173	histone kinase activity(GO:0035173)
1.1	44.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
1.1	35.4	GO:0008432	JUN kinase binding(GO:0008432)
1.1	4.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
1.1	33.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
1.1	14.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
1.1	7.6	GO:0089720	caspase binding(GO:0089720)
1.1	9.7	GO:0015198	oligopeptide transporter activity(GO:0015198)
1.1	9.5	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
1.0	4.1	GO:1990763	arrestin family protein binding(GO:1990763)
1.0	14.5	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.0	3.1	GO:0030116	glial cell-derived neurotrophic factor receptor binding(GO:0030116)
1.0	8.1	GO:0001069	regulatory region RNA binding(GO:0001069)
1.0	16.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.0	5.9	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.9	2.8	GO:0001096	TFIIF-class transcription factor binding(GO:0001096)
0.9	5.5	GO:0045322	unmethylated CpG binding(GO:0045322)
0.9	5.5	GO:0042296	ISG15 transferase activity(GO:0042296)
0.9	20.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.9	4.6	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.9	14.3	GO:0031386	protein tag(GO:0031386)
0.9	5.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.8	28.7	GO:0001968	fibronectin binding(GO:0001968)
0.8	4.9	GO:0033142	progesterone receptor binding(GO:0033142)
0.8	14.2	GO:0043495	protein anchor(GO:0043495)
0.8	2.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8	10.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.8	2.3	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.8	44.8	GO:0070063	RNA polymerase binding(GO:0070063)
0.7	7.3	GO:0043047	single-stranded telomeric DNA binding(GO:0043047)
0.7	4.0	GO:0034452	dynactin binding(GO:0034452)
0.7	4.7	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.7	5.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.7	77.8	GO:0004386	helicase activity(GO:0004386)
0.6	1.9	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.6	10.0	GO:0070182	DNA polymerase binding(GO:0070182)
0.6	1.9	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.6	1.8	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6	6.1	GO:1901612	cardiolipin binding(GO:1901612)
0.6	4.8	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.6	14.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.6	7.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6	8.9	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6	3.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.6	10.1	GO:0005522	profilin binding(GO:0005522)
0.6	4.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.6	121.4	GO:0042393	histone binding(GO:0042393)
0.6	1.7	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.6	3.4	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6	25.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.6	3.3	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.5	2.7	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.5	8.7	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5	36.5	GO:0003697	single-stranded DNA binding(GO:0003697)
0.5	54.2	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.5	4.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5	3.7	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.5	6.8	GO:0001055	RNA polymerase II activity(GO:0001055)
0.5	7.3	GO:0048156	tau protein binding(GO:0048156)
0.5	17.4	GO:0070840	dynein complex binding(GO:0070840)
0.5	36.5	GO:0070888	E-box binding(GO:0070888)
0.5	3.5	GO:0008420	CTD phosphatase activity(GO:0008420)
0.5	2.5	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.5	5.3	GO:1990405	protein antigen binding(GO:1990405)
0.5	6.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5	0.9	GO:0098808	mRNA cap binding(GO:0098808)
0.5	17.1	GO:0070412	R-SMAD binding(GO:0070412)
0.5	2.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.4	3.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	4.8	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.4	0.9	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.4	2.6	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4	2.6	GO:0048495	Roundabout binding(GO:0048495)
0.4	7.9	GO:0042288	MHC class I protein binding(GO:0042288)
0.4	17.5	GO:0008009	chemokine activity(GO:0008009)
0.4	2.5	GO:0035252	UDP-xylosyltransferase activity(GO:0035252)
0.4	1.7	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4	11.1	GO:0003684	damaged DNA binding(GO:0003684)
0.4	12.6	GO:0017025	TBP-class protein binding(GO:0017025)
0.4	7.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.4	9.6	GO:0017160	Ral GTPase binding(GO:0017160)
0.4	1.6	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4	3.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.4	7.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.4	5.5	GO:0004016	adenylate cyclase activity(GO:0004016)
0.4	3.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4	5.4	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.4	2.3	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4	19.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.4	6.4	GO:0003796	lysozyme activity(GO:0003796)
0.4	4.9	GO:0039706	co-receptor binding(GO:0039706)
0.4	6.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.4	41.0	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.4	2.6	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.4	1.8	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.4	2.5	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.3	11.5	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.3	10.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	4.3	GO:0004017	adenylate kinase activity(GO:0004017)
0.3	2.0	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3	4.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.3	10.4	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3	1.6	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.3	2.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.3	12.3	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	1.9	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	5.3	GO:0050897	cobalt ion binding(GO:0050897)
0.3	13.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.3	3.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.3	1.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	6.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	8.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	8.1	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
0.3	1.8	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.3	7.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3	0.9	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.3	2.9	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	3.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3	1.4	GO:1990188	euchromatin binding(GO:1990188)
0.3	9.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.3	3.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.3	0.5	GO:0070878	primary miRNA binding(GO:0070878)
0.3	3.0	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.3	4.1	GO:0004697	protein kinase C activity(GO:0004697)
0.3	2.4	GO:0005113	patched binding(GO:0005113)
0.3	10.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.3	3.7	GO:0001972	retinoic acid binding(GO:0001972)
0.3	1.0	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3	8.8	GO:0017166	vinculin binding(GO:0017166)
0.2	8.0	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.2	1.0	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	33.0	GO:0001047	core promoter binding(GO:0001047)
0.2	2.9	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2	1.7	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
0.2	2.3	GO:0004064	arylesterase activity(GO:0004064)
0.2	10.3	GO:0031369	translation initiation factor binding(GO:0031369)
0.2	3.1	GO:0070034	telomerase RNA binding(GO:0070034)
0.2	1.5	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.2	3.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	14.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.2	1.9	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.2	5.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	8.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2	2.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2	8.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	0.6	GO:0015292	uniporter activity(GO:0015292)
0.2	0.8	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990) transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2	10.1	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.2	0.7	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2	8.7	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2	7.0	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.2	12.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.2	1.8	GO:0035326	enhancer binding(GO:0035326)
0.2	1.7	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2	1.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	1.7	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.2	0.5	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.2	5.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	2.8	GO:0030275	LRR domain binding(GO:0030275)
0.2	3.9	GO:0004707	MAP kinase activity(GO:0004707)
0.2	1.0	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2	0.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.2	0.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2	7.9	GO:0002039	p53 binding(GO:0002039)
0.2	1.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2	4.4	GO:0005112	Notch binding(GO:0005112)
0.2	1.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.2	3.5	GO:0070717	poly-purine tract binding(GO:0070717)
0.2	4.2	GO:0031005	filamin binding(GO:0031005)
0.2	1.5	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.2	4.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	3.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	1.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	2.1	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1	1.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	53.7	GO:0003682	chromatin binding(GO:0003682)
0.1	5.7	GO:0008373	sialyltransferase activity(GO:0008373)
0.1	8.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	1.4	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	1.9	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	5.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	3.7	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.1	2.0	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1	13.6	GO:0003777	microtubule motor activity(GO:0003777)
0.1	1.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.6	GO:0030977	taurine binding(GO:0030977)
0.1	2.2	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.7	GO:0004359	glutaminase activity(GO:0004359)
0.1	1.8	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	40.6	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1	3.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	30.1	GO:0008022	protein C-terminus binding(GO:0008022)
0.1	3.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	2.9	GO:0008527	taste receptor activity(GO:0008527)
0.1	4.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	24.9	GO:0003690	double-stranded DNA binding(GO:0003690)
0.1	1.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	2.9	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.4	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	94.9	GO:0003677	DNA binding(GO:0003677)
0.1	0.8	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	1.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	0.3	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	1.0	GO:0009881	G-protein coupled photoreceptor activity(GO:0008020) photoreceptor activity(GO:0009881)
0.1	2.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	3.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.4	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	0.5	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	2.5	GO:0050699	WW domain binding(GO:0050699)
0.1	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.1	2.7	GO:0005109	frizzled binding(GO:0005109)
0.1	0.4	GO:0052724	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.3	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	1.7	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	1.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.2	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	1.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.4	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	16.4	GO:0003924	GTPase activity(GO:0003924)
0.1	3.5	GO:0051287	NAD binding(GO:0051287)
0.0	2.0	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.8	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	2.0	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	1.5	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	8.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	1.0	GO:0005537	mannose binding(GO:0005537)
0.0	4.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.5	GO:0015266	protein channel activity(GO:0015266)
0.0	1.6	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	1.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	2.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	3.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.6	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	1.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	3.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	7.8	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	63.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.8	147.5	PID ATR PATHWAY	ATR signaling pathway
2.2	223.0	PID E2F PATHWAY	E2F transcription factor network
1.7	97.9	PID AURORA B PATHWAY	Aurora B signaling
1.5	6.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.5	40.6	PID FANCONI PATHWAY	Fanconi anemia pathway
1.3	20.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.2	19.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.1	15.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.0	20.8	PID ATM PATHWAY	ATM pathway
0.9	15.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.9	25.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.9	23.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.9	45.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.8	10.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.8	25.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.7	2.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.6	44.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	13.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	26.1	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.5	30.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.5	27.0	PID P53 REGULATION PATHWAY	p53 pathway
0.4	9.9	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.4	32.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	10.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4	19.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	10.7	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.4	5.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	22.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.3	6.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.3	33.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	15.4	PID PLK1 PATHWAY	PLK1 signaling events
0.3	6.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.3	7.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.3	33.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	4.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	8.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.2	6.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	4.6	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.2	3.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	10.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.2	3.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	2.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	8.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	3.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	5.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	11.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	5.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	4.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	2.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	3.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	8.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	1.5	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	2.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	2.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	1.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	1.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	6.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.6	122.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
4.5	44.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
3.7	114.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
3.5	3.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
3.3	53.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
3.3	23.0	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
3.2	44.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
3.1	39.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
2.6	29.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
2.4	47.3	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
2.0	41.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.9	3.7	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.8	48.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
1.8	8.9	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.4	42.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.4	16.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
1.0	4.9	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
1.0	50.7	REACTOME MEIOSIS	Genes involved in Meiosis
0.9	0.9	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.9	142.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.8	7.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.8	4.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8	30.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.7	10.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.7	7.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.7	29.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.7	52.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.7	8.5	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.7	14.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.7	15.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.7	21.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.7	54.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	1.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.6	17.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.6	4.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.6	9.6	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.6	8.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6	14.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.6	7.0	REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	Genes involved in Cytokine Signaling in Immune system
0.6	15.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.6	35.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.6	7.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.5	13.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.5	3.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.5	35.8	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.5	3.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5	4.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5	4.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.5	10.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.5	3.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.5	3.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.5	11.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.5	19.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.4	61.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.4	7.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.4	3.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4	9.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.4	5.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.4	3.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.4	13.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4	3.8	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.4	5.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.4	7.7	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.4	6.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.4	2.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.3	5.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.3	19.7	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.3	2.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	12.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3	4.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.3	3.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	5.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	11.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	2.5	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.3	27.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.3	2.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	9.5	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.2	4.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2	5.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	12.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	6.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	3.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	18.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	3.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	14.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	2.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	2.5	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.2	1.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.2	1.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	8.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	3.0	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.2	44.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	3.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	3.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	4.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	5.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	4.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.1	4.0	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	3.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	6.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.0	REACTOME OPSINS	Genes involved in Opsins
0.1	1.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	6.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	3.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	1.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	0.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	2.9	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	1.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.3	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones

Results for E2f1

Z-value: 4.01

Motif logo

Transcription factors associated with E2f1

Activity-expression correlation:

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: