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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for E2f3

Z-value: 1.00

Motif logo

Transcription factors associated with E2f3

Gene Symbol Gene ID Gene Info
ENSMUSG00000016477.19 E2f3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f3mm39_v1_chr13_-_30170031_301700480.361.7e-03Click!

Activity profile of E2f3 motif

Sorted Z-values of E2f3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_113957362 15.52 ENSMUST00000202555.2
selectin, platelet (p-selectin) ligand
chr5_-_113957318 13.83 ENSMUST00000201194.4
selectin, platelet (p-selectin) ligand
chr11_+_11635908 9.15 ENSMUST00000065433.12
IKAROS family zinc finger 1
chr2_-_126975804 5.67 ENSMUST00000110387.4
non-SMC condensin I complex, subunit H
chr12_+_24758968 5.05 ENSMUST00000154588.2
ribonucleotide reductase M2
chr12_-_69274936 4.55 ENSMUST00000221411.2
ENSMUST00000021359.7
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr4_+_43957401 4.32 ENSMUST00000030202.14
GLI pathogenesis-related 2
chr6_+_120440159 4.13 ENSMUST00000002976.5
interleukin 17 receptor A
chr8_+_123294740 4.11 ENSMUST00000006760.3
chromatin licensing and DNA replication factor 1
chr2_+_109111083 4.09 ENSMUST00000028527.8
kinesin family member 18A
chr5_-_65855511 4.06 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr12_+_24758724 4.04 ENSMUST00000153058.8
ribonucleotide reductase M2
chr4_+_43957677 4.01 ENSMUST00000107855.2
GLI pathogenesis-related 2
chrX_-_50294652 3.96 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr17_+_34372046 3.95 ENSMUST00000114232.4
histocompatibility 2, class II, locus Mb1
chr11_-_101442663 3.88 ENSMUST00000017290.11
breast cancer 1, early onset
chr12_+_24758240 3.81 ENSMUST00000020980.12
ribonucleotide reductase M2
chr7_+_13012735 3.78 ENSMUST00000098814.13
ENSMUST00000146998.9
ligase I, DNA, ATP-dependent
chr2_+_117942357 3.66 ENSMUST00000039559.9
thrombospondin 1
chr1_-_95595280 3.63 ENSMUST00000043336.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr13_-_55477535 3.39 ENSMUST00000021941.8
Max dimerization protein 3
chr18_+_11790409 3.38 ENSMUST00000047322.8
retinoblastoma binding protein 8, endonuclease
chrX_-_101232978 3.36 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr2_+_172821620 3.32 ENSMUST00000109125.8
ENSMUST00000109126.5
ENSMUST00000050442.15
SPO11 initiator of meiotic double stranded breaks
chr15_-_79967543 3.31 ENSMUST00000081650.15
ribosomal protein L3
chr10_+_20223516 3.27 ENSMUST00000169712.3
ENSMUST00000217608.2
mitochondrial fission regulator 2
chr9_-_22043083 3.25 ENSMUST00000069330.14
ENSMUST00000217643.2
acid phosphatase 5, tartrate resistant
chr11_+_60066681 3.20 ENSMUST00000102688.2
retinoic acid induced 1
chr3_+_68912302 3.20 ENSMUST00000136502.8
ENSMUST00000107803.7
structural maintenance of chromosomes 4
chr17_-_71782296 3.14 ENSMUST00000127430.2
SMC hinge domain containing 1
chr16_-_4536992 3.08 ENSMUST00000115851.10
NmrA-like family domain containing 1
chr10_-_34003933 3.02 ENSMUST00000062784.8
calcium homeostasis modulator family member 6
chr16_-_4536943 3.02 ENSMUST00000120056.8
ENSMUST00000074970.8
NmrA-like family domain containing 1
chr10_-_93425553 2.86 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr9_-_22042930 2.86 ENSMUST00000213815.2
acid phosphatase 5, tartrate resistant
chr18_+_11790888 2.82 ENSMUST00000234499.2
retinoblastoma binding protein 8, endonuclease
chr2_+_150751475 2.78 ENSMUST00000028948.5
GINS complex subunit 1 (Psf1 homolog)
chr9_+_64188857 2.72 ENSMUST00000215031.2
ENSMUST00000213165.2
ENSMUST00000213289.2
ENSMUST00000216594.2
ENSMUST00000034964.7
timeless interacting protein
chr9_+_44151962 2.72 ENSMUST00000092426.5
ENSMUST00000217221.2
ENSMUST00000213891.2
coiled-coil domain containing 153
chr15_-_83479312 2.69 ENSMUST00000016901.5
tubulin tyrosine ligase-like family, member 12
chr5_-_65855199 2.63 ENSMUST00000031104.7
PDS5 cohesin associated factor A
chr13_-_51947685 2.58 ENSMUST00000110040.9
ENSMUST00000021900.14
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr9_+_56979307 2.56 ENSMUST00000169879.8
transcriptional regulator, SIN3A (yeast)
chr6_-_34887743 2.55 ENSMUST00000081214.12
WD repeat domain 91
chr5_-_100867520 2.44 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chr9_+_44152029 2.40 ENSMUST00000217510.2
ENSMUST00000216632.2
coiled-coil domain containing 153
chr18_+_67933169 2.31 ENSMUST00000025425.7
centrosomal protein 192
chr3_+_97920819 2.27 ENSMUST00000079812.8
notch 2
chr10_-_60983404 2.25 ENSMUST00000122259.8
sphingosine phosphate lyase 1
chr19_+_40883127 2.23 ENSMUST00000050092.7
zinc finger protein 518A
chr12_-_21423607 2.22 ENSMUST00000064536.13
a disintegrin and metallopeptidase domain 17
chr10_-_60983438 2.22 ENSMUST00000092498.12
ENSMUST00000137833.2
ENSMUST00000155919.8
sphingosine phosphate lyase 1
chr11_+_115455260 2.20 ENSMUST00000021085.11
nucleoporin 85
chr12_-_21423524 2.17 ENSMUST00000232107.2
a disintegrin and metallopeptidase domain 17
chr15_-_67048595 2.17 ENSMUST00000229213.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr5_-_68004743 2.15 ENSMUST00000072971.13
ENSMUST00000113652.8
ENSMUST00000113651.8
ENSMUST00000037380.15
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr15_-_67048673 2.11 ENSMUST00000229028.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chrX_-_104972938 2.01 ENSMUST00000198448.5
ENSMUST00000199233.5
ENSMUST00000134507.8
ENSMUST00000154866.8
ENSMUST00000128968.8
ENSMUST00000134381.8
ENSMUST00000150914.8
ATRX, chromatin remodeler
chr3_-_95125190 1.95 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chrX_-_104973003 1.95 ENSMUST00000130980.2
ENSMUST00000113573.8
ATRX, chromatin remodeler
chr6_-_88818832 1.92 ENSMUST00000032169.8
ankyrin repeat and BTB (POZ) domain containing 1
chr3_-_84387700 1.92 ENSMUST00000194027.2
ENSMUST00000107689.7
FH2 domain containing 1
chr3_-_51248032 1.91 ENSMUST00000062009.14
ENSMUST00000194641.6
E74-like factor 2
chr2_+_31560725 1.91 ENSMUST00000038474.14
ENSMUST00000137156.2
exosome component 2
chr16_+_91282121 1.89 ENSMUST00000023689.11
ENSMUST00000117748.8
interferon (alpha and beta) receptor 1
chr12_-_21423551 1.86 ENSMUST00000101551.10
a disintegrin and metallopeptidase domain 17
chr17_-_33007238 1.85 ENSMUST00000159086.10
zinc finger protein 871
chr10_+_75152705 1.82 ENSMUST00000105420.3
adenosine A2a receptor
chr9_-_57673128 1.82 ENSMUST00000065330.8
CDC-like kinase 3
chr4_+_11486002 1.82 ENSMUST00000108307.3
vir like m6A methyltransferase associated
chr12_-_4924341 1.79 ENSMUST00000137337.8
ENSMUST00000045921.14
major facilitator superfamily domain containing 2B
chr3_-_95125002 1.77 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr4_+_11485945 1.74 ENSMUST00000055372.14
ENSMUST00000059914.13
vir like m6A methyltransferase associated
chr17_+_27136065 1.74 ENSMUST00000078961.6
kinesin family member C5B
chr17_+_24971952 1.69 ENSMUST00000044922.8
ENSMUST00000234202.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr2_+_34999497 1.69 ENSMUST00000028235.11
ENSMUST00000156933.8
ENSMUST00000028237.15
ENSMUST00000113032.8
centriolin
chr4_-_123558516 1.67 ENSMUST00000147030.2
microtubule-actin crosslinking factor 1
chr15_-_89033761 1.66 ENSMUST00000088823.5
mitogen-activated protein kinase 11
chr1_-_91340884 1.65 ENSMUST00000086851.2
hairy and enhancer of split 6
chr15_+_73384407 1.62 ENSMUST00000043414.12
DENN/MADD domain containing 3
chr12_-_100865783 1.58 ENSMUST00000053668.10
G protein-coupled receptor 68
chr17_+_29251602 1.57 ENSMUST00000130216.3
serine and arginine-rich splicing factor 3
chr18_-_52662728 1.56 ENSMUST00000025409.9
lysyl oxidase
chr16_+_91444730 1.55 ENSMUST00000119368.8
ENSMUST00000114037.9
ENSMUST00000114036.9
ENSMUST00000122302.8
Son DNA binding protein
chr14_-_30348153 1.49 ENSMUST00000112211.9
ENSMUST00000112210.11
protein kinase C, delta
chr10_-_80512117 1.49 ENSMUST00000200082.5
MAP kinase-interacting serine/threonine kinase 2
chr13_-_21586858 1.49 ENSMUST00000117721.8
ENSMUST00000070785.16
ENSMUST00000116433.2
ENSMUST00000223831.2
ENSMUST00000116434.11
ENSMUST00000224820.2
zinc finger with KRAB and SCAN domains 3
chr1_-_191307648 1.48 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr3_-_68911807 1.47 ENSMUST00000154741.8
ENSMUST00000148031.2
intraflagellar transport 80
chr4_-_140805613 1.46 ENSMUST00000030760.15
NECAP endocytosis associated 2
chr19_+_53588808 1.46 ENSMUST00000025930.10
structural maintenance of chromosomes 3
chr18_+_31922173 1.46 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr3_-_68911835 1.42 ENSMUST00000107812.8
intraflagellar transport 80
chr2_+_52747855 1.40 ENSMUST00000155586.9
ENSMUST00000090952.11
ENSMUST00000127122.9
ENSMUST00000049483.14
ENSMUST00000050719.13
formin-like 2
chrX_-_104972844 1.38 ENSMUST00000198441.5
ENSMUST00000137453.8
ATRX, chromatin remodeler
chr1_-_128287347 1.36 ENSMUST00000190495.2
ENSMUST00000027601.11
minichromosome maintenance complex component 6
chr17_+_34258411 1.35 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
collagen, type XI, alpha 2
chr3_-_84063067 1.34 ENSMUST00000047368.8
meiotic nuclear divisions 1
chr3_-_68911886 1.34 ENSMUST00000169064.8
intraflagellar transport 80
chr5_-_68004702 1.32 ENSMUST00000135930.8
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr17_-_56891576 1.28 ENSMUST00000075510.12
scaffold attachment factor B2
chr8_-_70449018 1.28 ENSMUST00000065169.12
ENSMUST00000212478.2
GATA zinc finger domain containing 2A
chr4_-_34614883 1.24 ENSMUST00000140334.2
ENSMUST00000108142.8
ENSMUST00000048706.10
origin recognition complex, subunit 3
chr3_+_66892979 1.23 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chr7_-_5016237 1.22 ENSMUST00000208944.2
Flt3 interacting zinc finger protein 1
chr4_+_57821050 1.20 ENSMUST00000238994.2
paralemmin A kinase anchor protein
chr6_-_72322116 1.19 ENSMUST00000070345.5
ubiquitin specific peptidase 39
chr16_+_91282183 1.18 ENSMUST00000129878.2
interferon (alpha and beta) receptor 1
chr9_-_62888156 1.17 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr9_-_20888054 1.10 ENSMUST00000054197.7
sphingosine-1-phosphate receptor 2
chr1_+_156386414 1.09 ENSMUST00000166172.9
ENSMUST00000027888.13
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr10_+_80062468 1.09 ENSMUST00000130260.2
PWWP domain containing 3A, DNA repair factor
chr10_-_80754016 1.08 ENSMUST00000057623.14
ENSMUST00000179022.8
lamin B2
chr15_+_99122742 1.06 ENSMUST00000041415.5
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr13_-_21715202 1.06 ENSMUST00000156674.3
ENSMUST00000110481.3
ENSMUST00000045228.12
zinc finger with KRAB and SCAN domains 8
chr19_-_5416626 1.06 ENSMUST00000237167.2
BAF nuclear assembly factor 1
chr11_+_65698001 1.06 ENSMUST00000071465.9
ENSMUST00000018491.8
zinc finger with KRAB and SCAN domains 6
chr6_-_71417607 1.05 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr11_-_86435579 1.05 ENSMUST00000138810.3
ENSMUST00000058286.9
ENSMUST00000154617.8
ribosomal protein S6 kinase, polypeptide 1
chrX_-_101114906 1.03 ENSMUST00000188731.2
retrotransposon Gag like 5
chr11_+_21189277 1.02 ENSMUST00000109578.8
ENSMUST00000006221.14
VPS54 GARP complex subunit
chr2_-_168432111 1.01 ENSMUST00000029057.13
ENSMUST00000074618.10
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr9_+_21914083 1.00 ENSMUST00000216344.2
protein kinase C substrate 80K-H
chr1_-_91326490 1.00 ENSMUST00000190519.2
ENSMUST00000027534.13
ENSMUST00000187306.7
integrin-linked kinase-associated serine/threonine phosphatase 2C
chr1_-_95595245 0.99 ENSMUST00000189556.2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr7_-_80338600 0.98 ENSMUST00000122255.8
CREB regulated transcription coactivator 3
chr18_+_75500600 0.97 ENSMUST00000026999.10
SMAD family member 7
chrX_+_93768175 0.96 ENSMUST00000101388.4
zinc finger, X-linked, duplicated B
chr10_-_30476658 0.96 ENSMUST00000019927.7
tRNA methyltransferase 11
chr18_+_44513547 0.92 ENSMUST00000202306.2
ENSMUST00000025350.10
decapping mRNA 2
chrX_-_101114794 0.91 ENSMUST00000113631.2
retrotransposon Gag like 5
chr17_+_64907697 0.91 ENSMUST00000086723.10
mannosidase 2, alpha 1
chr4_+_109137561 0.88 ENSMUST00000177089.8
ENSMUST00000175776.8
ENSMUST00000132165.9
epidermal growth factor receptor pathway substrate 15
chr9_-_44876817 0.88 ENSMUST00000214761.2
ENSMUST00000213666.2
ENSMUST00000213890.2
ENSMUST00000125642.8
ENSMUST00000213193.2
ENSMUST00000117506.9
ENSMUST00000138559.9
ENSMUST00000117549.8
ubiquitination factor E4A
chr17_-_80369626 0.88 ENSMUST00000184635.8
heterogeneous nuclear ribonucleoprotein L-like
chr8_-_57940834 0.88 ENSMUST00000034022.4
sin3 associated polypeptide
chr9_+_63509925 0.88 ENSMUST00000041551.9
alpha- and gamma-adaptin binding protein
chr8_-_70448872 0.87 ENSMUST00000177851.9
GATA zinc finger domain containing 2A
chrX_-_8042129 0.87 ENSMUST00000143984.2
TBC1 domain family, member 25
chr15_+_84116231 0.87 ENSMUST00000023072.7
parvin, beta
chr5_-_148336711 0.86 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_92653377 0.84 ENSMUST00000031377.9
scavenger receptor class B, member 2
chr1_-_4563821 0.84 ENSMUST00000191939.2
SRY (sex determining region Y)-box 17
chr4_+_109137462 0.83 ENSMUST00000102729.10
epidermal growth factor receptor pathway substrate 15
chr2_+_151753119 0.82 ENSMUST00000028955.6
angiopoietin 4
chr18_-_84607615 0.79 ENSMUST00000125763.3
zinc finger protein 407
chr3_-_41696906 0.79 ENSMUST00000026866.15
sodium channel and clathrin linker 1
chrX_+_20570145 0.77 ENSMUST00000033383.3
ubiquitin specific peptidase 11
chrX_+_73326303 0.77 ENSMUST00000069722.13
ENSMUST00000124200.8
ENSMUST00000114180.11
ENSMUST00000132437.8
tafazzin
chr14_+_73381003 0.76 ENSMUST00000110952.10
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr19_+_3373285 0.75 ENSMUST00000025835.6
carnitine palmitoyltransferase 1a, liver
chr11_-_62348599 0.75 ENSMUST00000127471.9
nuclear receptor co-repressor 1
chr9_+_22099386 0.75 ENSMUST00000217301.2
ENSMUST00000178901.8
zinc finger protein 872
chr8_-_120331936 0.74 ENSMUST00000093099.13
TATA-box binding protein associated factor, RNA polymerase I, C
chr17_+_36152383 0.71 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr3_+_66893031 0.70 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr11_-_84020382 0.69 ENSMUST00000018795.13
transcriptional adaptor 2A
chr16_-_78173645 0.69 ENSMUST00000023570.14
BTG anti-proliferation factor 3
chr4_+_116565706 0.68 ENSMUST00000030452.13
ENSMUST00000106462.9
coiled-coil domain containing 163
chr10_+_33780993 0.68 ENSMUST00000169670.8
radial spoke head 4 homolog A (Chlamydomonas)
chr9_+_113760376 0.68 ENSMUST00000214095.2
ENSMUST00000116492.3
ENSMUST00000216558.2
upstream binding protein 1
chr5_-_34093678 0.66 ENSMUST00000030993.8
negative elongation factor complex member A, Whsc2
chr4_+_116565784 0.65 ENSMUST00000138305.8
ENSMUST00000125671.8
ENSMUST00000130828.8
coiled-coil domain containing 163
chr5_-_39801940 0.65 ENSMUST00000152057.2
ENSMUST00000053116.7
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr7_+_34818709 0.64 ENSMUST00000205391.2
ENSMUST00000042985.11
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_-_4319170 0.64 ENSMUST00000037992.16
ENSMUST00000113852.6
ENSMUST00000236794.2
slingshot protein phosphatase 3
chr10_+_43354807 0.64 ENSMUST00000167488.9
BEN domain containing 3
chr17_-_80369762 0.64 ENSMUST00000061331.14
heterogeneous nuclear ribonucleoprotein L-like
chr2_-_168432235 0.63 ENSMUST00000109184.8
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr17_-_24877431 0.63 ENSMUST00000095544.6
neuropeptide W
chr19_+_5416769 0.62 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr3_-_95125051 0.60 ENSMUST00000107204.8
GA repeat binding protein, beta 2
chr17_-_48145466 0.60 ENSMUST00000066368.13
MyoD family inhibitor
chr3_+_33853941 0.60 ENSMUST00000099153.10
tetratricopeptide repeat domain 14
chr10_+_43355113 0.58 ENSMUST00000040147.8
BEN domain containing 3
chr8_+_71995554 0.55 ENSMUST00000034272.9
multivesicular body subunit 12A
chr3_+_33854305 0.55 ENSMUST00000196139.5
ENSMUST00000200271.5
ENSMUST00000198529.5
ENSMUST00000117915.8
ENSMUST00000108210.9
ENSMUST00000196975.5
tetratricopeptide repeat domain 14
chr15_+_99870661 0.54 ENSMUST00000100206.4
La ribonucleoprotein domain family, member 4
chr12_+_111505216 0.53 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr2_-_180929828 0.52 ENSMUST00000049032.13
glucocorticoid modulatory element binding protein 2
chr8_+_106587212 0.52 ENSMUST00000008594.9
nuclear transport factor 2
chr7_+_100021425 0.52 ENSMUST00000098259.11
ENSMUST00000051777.15
C2 calcium-dependent domain containing 3
chr11_-_72097821 0.52 ENSMUST00000204457.3
predicted gene, 43951
chr16_-_44153288 0.52 ENSMUST00000136381.8
SID1 transmembrane family, member 1
chr8_+_84626715 0.52 ENSMUST00000141158.8
adhesion G protein-coupled receptor L1
chr9_+_72892850 0.51 ENSMUST00000150826.9
ENSMUST00000085350.11
ENSMUST00000140675.8
cell cycle progression 1
chr8_-_124586159 0.50 ENSMUST00000034452.12
centriole, cilia and spindle associated protein
chr10_+_75152908 0.50 ENSMUST00000219044.2
adenosine A2a receptor
chr16_-_43709968 0.48 ENSMUST00000023387.14
queuine tRNA-ribosyltransferase accessory subunit 2
chr6_-_97594498 0.48 ENSMUST00000113355.9
FERM domain containing 4B
chr2_+_115412148 0.48 ENSMUST00000166472.8
ENSMUST00000110918.3
CDAN1 interacting nuclease 1
chr18_+_47245204 0.47 ENSMUST00000234633.2
heat shock protein 1 (chaperonin 10), related sequence 1
chr5_-_148336574 0.47 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_-_20199359 0.47 ENSMUST00000050611.14
ENSMUST00000109596.8
ENSMUST00000162811.2
centrosomal protein 68
chr1_-_16689527 0.46 ENSMUST00000182554.9
ubiquitin-conjugating enzyme E2W (putative)
chr12_+_80992294 0.46 ENSMUST00000110354.8
ENSMUST00000110352.10
ENSMUST00000110351.8
ENSMUST00000110356.3
serine and arginine-rich splicing factor 5
chr9_-_105837842 0.46 ENSMUST00000190193.8
ENSMUST00000165165.3
collagen, type VI, alpha 5
chrX_-_73129195 0.43 ENSMUST00000140399.3
ENSMUST00000123362.8
ENSMUST00000100750.10
ENSMUST00000033770.13
methyl CpG binding protein 2
chr13_+_54722833 0.40 ENSMUST00000156024.2
ADP-ribosylation factor-like 10
chr18_+_9957906 0.37 ENSMUST00000025137.9
THO complex 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
3.1 9.2 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.4 5.7 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.4 4.1 GO:0072708 mediator complex assembly(GO:0036034) DNA replication preinitiation complex assembly(GO:0071163) response to sorbitol(GO:0072708) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
1.2 1.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.2 3.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
1.1 3.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.0 3.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.0 6.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.9 4.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.9 5.3 GO:0035127 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.8 2.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.8 3.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.8 6.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.8 2.3 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.7 6.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.7 6.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.7 4.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.6 2.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.6 2.6 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.6 12.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 2.7 GO:0048478 replication fork protection(GO:0048478)
0.5 0.5 GO:0061511 centriole elongation(GO:0061511)
0.5 1.5 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.5 1.9 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.5 2.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.4 4.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 1.5 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.4 3.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 4.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 3.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.1 GO:0019043 establishment of viral latency(GO:0019043)
0.3 1.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 8.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 3.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 0.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.3 3.6 GO:0080009 mRNA methylation(GO:0080009)
0.2 3.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2 0.9 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 2.2 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 4.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.8 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807)
0.2 1.7 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 1.4 GO:0060023 soft palate development(GO:0060023)
0.2 0.2 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 0.7 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 1.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.2 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.7 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 1.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 4.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.5 GO:0006168 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 8.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.0 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.4 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 4.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042) positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.4 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 2.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 3.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 3.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 4.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.3 GO:0015809 arginine transport(GO:0015809)
0.1 1.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 1.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.6 GO:0000050 urea cycle(GO:0000050)
0.1 0.9 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 3.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 2.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 2.3 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.9 GO:0006414 translational elongation(GO:0006414)
0.0 1.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0 1.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.5 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 3.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 1.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.7 29.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.2 1.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.1 5.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.9 2.8 GO:0000811 GINS complex(GO:0000811)
0.9 4.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.9 5.3 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.8 3.1 GO:0001740 Barr body(GO:0001740)
0.8 9.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 2.7 GO:0031298 replication fork protection complex(GO:0031298)
0.5 4.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 3.6 GO:0036396 MIS complex(GO:0036396)
0.5 2.9 GO:0005683 U7 snRNP(GO:0005683)
0.5 3.2 GO:0000796 condensin complex(GO:0000796)
0.4 3.7 GO:0005577 fibrinogen complex(GO:0005577)
0.4 3.9 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 3.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 1.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.1 GO:0034657 GID complex(GO:0034657)
0.2 4.2 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.0 GO:0000938 GARP complex(GO:0000938)
0.2 1.0 GO:0017177 glucosidase II complex(GO:0017177)
0.2 0.8 GO:0043202 lysosomal lumen(GO:0043202)
0.2 0.7 GO:0032021 NELF complex(GO:0032021)
0.2 1.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 2.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 0.7 GO:0000125 PCAF complex(GO:0000125)
0.1 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 4.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 3.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 2.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 2.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 4.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0016342 catenin complex(GO:0016342)
0.1 6.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.9 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 4.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 12.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 3.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 4.1 GO:0000776 kinetochore(GO:0000776)
0.0 3.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 4.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 3.4 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.9 3.7 GO:0070052 collagen V binding(GO:0070052)
0.8 3.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.8 5.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.8 4.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8 5.3 GO:0015616 DNA translocase activity(GO:0015616)
0.6 6.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.5 2.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.5 4.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 4.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 6.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 2.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 3.8 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.4 1.5 GO:0036033 mediator complex binding(GO:0036033)
0.3 5.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 0.9 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.3 2.0 GO:0050733 RS domain binding(GO:0050733)
0.3 1.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 0.8 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 2.4 GO:0045545 syndecan binding(GO:0045545)
0.2 9.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 3.3 GO:0008097 5S rRNA binding(GO:0008097)
0.2 4.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 0.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 2.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 0.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 1.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 4.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 0.5 GO:0003999 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.1 1.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 4.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.0 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.2 GO:0000182 rDNA binding(GO:0000182)
0.1 1.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.4 GO:0019843 rRNA binding(GO:0019843)
0.1 2.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 2.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 4.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 3.2 GO:0035326 enhancer binding(GO:0035326)
0.0 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 6.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 29.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 12.4 PID ATM PATHWAY ATM pathway
0.3 3.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 8.9 PID AURORA B PATHWAY Aurora B signaling
0.1 5.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 13.8 PID E2F PATHWAY E2F transcription factor network
0.1 5.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 10.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 6.3 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.8 PID ATR PATHWAY ATR signaling pathway
0.1 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 4.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 17.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.6 8.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5 8.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 11.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.3 4.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 4.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 4.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 4.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 3.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.0 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 4.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 6.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 4.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 6.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 5.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis