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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for E2f4

Z-value: 2.36

Motif logo

Transcription factors associated with E2f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000014859.10 E2f4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f4mm39_v1_chr8_+_106024294_1060243670.883.2e-24Click!

Activity profile of E2f4 motif

Sorted Z-values of E2f4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_70703409 25.59 ENSMUST00000103410.3
immunoglobulin kappa constant
chr11_+_68936457 22.76 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr8_-_54091980 21.86 ENSMUST00000047768.11
nei like 3 (E. coli)
chr6_+_124807176 21.79 ENSMUST00000131847.8
ENSMUST00000151674.3
cell division cycle associated 3
chr9_+_72345801 21.50 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr1_-_169358912 21.42 ENSMUST00000192248.2
ENSMUST00000028000.13
NUF2, NDC80 kinetochore complex component
chr1_-_189420270 21.39 ENSMUST00000171929.8
ENSMUST00000165962.2
centromere protein F
chr9_+_72345267 21.29 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr4_+_134238310 20.26 ENSMUST00000105866.3
aurora kinase A and ninein interacting protein
chr1_-_169359015 19.93 ENSMUST00000111368.8
NUF2, NDC80 kinetochore complex component
chr15_+_79776597 19.83 ENSMUST00000175714.8
ENSMUST00000109620.10
ENSMUST00000165537.8
ENSMUST00000175752.8
ENSMUST00000176325.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr18_-_34884555 19.35 ENSMUST00000060710.9
cell division cycle 25C
chr19_+_6135013 18.84 ENSMUST00000025704.3
cell division cycle associated 5
chr14_-_87378641 16.61 ENSMUST00000168889.3
ENSMUST00000022599.14
diaphanous related formin 3
chr10_-_87982732 16.42 ENSMUST00000164121.8
ENSMUST00000164803.2
ENSMUST00000168163.8
ENSMUST00000048518.16
PARP1 binding protein
chr4_-_133694607 16.15 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr7_-_37806912 15.41 ENSMUST00000108023.10
cyclin E1
chr11_-_101442663 15.20 ENSMUST00000017290.11
breast cancer 1, early onset
chr4_-_133694543 15.13 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr7_-_92523396 14.95 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chr6_+_113508636 14.87 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr4_-_115980813 14.27 ENSMUST00000102704.4
ENSMUST00000102705.10
RAD54 like (S. cerevisiae)
chr4_-_132072988 13.95 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr18_+_56840813 13.93 ENSMUST00000025486.9
lamin B1
chr4_-_132073048 13.62 ENSMUST00000084250.11
regulator of chromosome condensation 1
chr1_+_52669849 13.35 ENSMUST00000165859.8
nuclear envelope integral membrane protein 2
chr12_+_24758240 12.94 ENSMUST00000020980.12
ribonucleotide reductase M2
chr13_-_74085880 12.51 ENSMUST00000022053.11
thyroid hormone receptor interactor 13
chr16_-_90524214 12.33 ENSMUST00000099554.5
MIS18 kinetochore protein A
chr2_+_24257576 12.05 ENSMUST00000140547.2
ENSMUST00000102942.8
pleckstrin and Sec7 domain containing 4
chr17_-_25946370 11.74 ENSMUST00000170070.3
ENSMUST00000048054.14
CTF18, chromosome transmission fidelity factor 18
chr18_-_60981981 11.33 ENSMUST00000177172.8
ENSMUST00000175934.8
ENSMUST00000176630.8
treacle ribosome biogenesis factor 1
chr4_+_11558905 11.13 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr12_+_117807607 10.50 ENSMUST00000176735.8
ENSMUST00000177339.2
cell division cycle associated 7 like
chr16_-_30129591 10.37 ENSMUST00000061190.8
glycoprotein 5 (platelet)
chr4_-_133695264 10.36 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr9_+_44245981 10.28 ENSMUST00000052686.4
H2A.X variant histone
chr4_-_133695204 9.92 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr9_+_107828136 9.79 ENSMUST00000049348.9
ENSMUST00000194271.2
TRAF-interacting protein
chr1_-_33708876 9.12 ENSMUST00000027312.11
DNA primase, p58 subunit
chr8_+_108271643 8.86 ENSMUST00000212543.2
WW domain containing E3 ubiquitin protein ligase 2
chr6_-_56681657 8.68 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_162896602 8.54 ENSMUST00000018005.10
myeloblastosis oncogene-like 2
chrX_+_141464393 8.34 ENSMUST00000112889.8
ENSMUST00000101198.9
ENSMUST00000112891.8
ENSMUST00000087333.9
transmembrane protein 164
chrX_-_165992145 8.22 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr5_+_31046196 8.18 ENSMUST00000069705.11
ENSMUST00000201917.4
ENSMUST00000201168.4
ENSMUST00000202060.4
ENSMUST00000201225.4
ENSMUST00000114700.9
ATP/GTP binding protein-like 5
chr15_-_76524097 8.08 ENSMUST00000168185.8
tonsoku-like, DNA repair protein
chrX_+_163763588 8.00 ENSMUST00000167446.8
ENSMUST00000057150.8
Fanconi anemia, complementation group B
chr2_+_112114906 7.80 ENSMUST00000053666.8
solute carrier family 12, member 6
chr7_+_126380655 7.68 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chr8_+_18645144 7.25 ENSMUST00000039412.15
microcephaly, primary autosomal recessive 1
chr4_-_59783780 7.00 ENSMUST00000107526.8
ENSMUST00000095063.11
INTS3 and NABP interacting protein
chr5_-_33809872 6.87 ENSMUST00000057551.14
stem-loop binding protein
chrX_+_8137372 6.63 ENSMUST00000127103.8
ENSMUST00000115591.8
solute carrier family 38, member 5
chr12_+_105976463 6.56 ENSMUST00000072040.7
vaccinia related kinase 1
chr5_+_21577640 6.38 ENSMUST00000035799.6
fibrinogen-like protein 2
chr17_+_35219941 6.26 ENSMUST00000087315.14
valyl-tRNA synthetase
chr5_-_33809640 6.21 ENSMUST00000151081.2
ENSMUST00000139518.8
ENSMUST00000101354.10
stem-loop binding protein
chr2_-_3513783 6.10 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
predicted gene 45902
heat shock protein 14
chr17_+_35201074 6.02 ENSMUST00000007266.14
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr12_+_105976533 5.98 ENSMUST00000085026.12
ENSMUST00000021539.16
vaccinia related kinase 1
chr9_-_82857528 5.92 ENSMUST00000034787.12
pleckstrin homology domain interacting protein
chr5_-_138170644 5.78 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr2_+_180961507 5.77 ENSMUST00000098971.11
ENSMUST00000054622.15
ENSMUST00000108814.8
ENSMUST00000048608.16
ENSMUST00000108815.8
regulator of telomere elongation helicase 1
chr17_-_35265702 5.76 ENSMUST00000097338.11
mutS homolog 5
chr6_-_69394425 5.74 ENSMUST00000199160.2
immunoglobulin kappa chain variable 4-61
chr17_+_35219998 5.68 ENSMUST00000173584.8
valyl-tRNA synthetase
chrX_+_8137620 5.60 ENSMUST00000033512.11
solute carrier family 38, member 5
chr15_+_57775595 5.48 ENSMUST00000022992.13
TBC1 domain family, member 31
chrX_+_8137881 5.33 ENSMUST00000115590.2
solute carrier family 38, member 5
chr10_+_87982854 5.24 ENSMUST00000052355.15
nucleoporin 37
chr11_+_16901370 5.20 ENSMUST00000109635.2
ENSMUST00000061327.2
F-box protein 48
chr5_+_123214332 5.18 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr11_+_74510413 5.13 ENSMUST00000100866.3
coiled-coil domain containing 92B
chr17_-_84495364 5.10 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr19_-_5416626 5.05 ENSMUST00000237167.2
BAF nuclear assembly factor 1
chr10_+_87982916 5.04 ENSMUST00000169309.3
nucleoporin 37
chr5_-_24652775 4.99 ENSMUST00000123167.2
ENSMUST00000030799.15
transmembrane and ubiquitin-like domain containing 1
chr17_+_35201130 4.95 ENSMUST00000173004.2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr7_+_58307930 4.94 ENSMUST00000168747.3
ATPase, class V, type 10A
chr9_-_32255604 4.93 ENSMUST00000034533.7
potassium inwardly-rectifying channel, subfamily J, member 5
chr5_-_33809683 4.82 ENSMUST00000075670.13
stem-loop binding protein
chr1_+_9868332 4.74 ENSMUST00000166384.8
ENSMUST00000168907.8
serum/glucocorticoid regulated kinase 3
chr4_-_3835595 4.72 ENSMUST00000138502.2
ribosomal protein S20
chr5_-_92496730 4.60 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr12_+_99850756 4.59 ENSMUST00000153627.8
tyrosyl-DNA phosphodiesterase 1
chr9_+_108820846 4.53 ENSMUST00000198140.5
ENSMUST00000051873.15
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr13_-_23929490 4.49 ENSMUST00000091752.5
H3 clustered histone 3
chr9_+_57615816 4.48 ENSMUST00000043990.14
ENSMUST00000142807.2
enhancer of mRNA decapping 3
chrX_+_104123341 4.42 ENSMUST00000033577.11
polysaccharide biosynthesis domain containing 1
chr5_-_138170077 4.42 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr15_-_78280099 4.41 ENSMUST00000229878.2
ENSMUST00000165170.8
ENSMUST00000074380.14
testis expressed 33
chr8_+_124750133 4.36 ENSMUST00000034457.9
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr2_+_129435448 4.31 ENSMUST00000049262.14
ENSMUST00000163034.8
ENSMUST00000160276.2
signal-regulatory protein alpha
chr17_+_31515163 4.26 ENSMUST00000235972.2
ENSMUST00000165149.3
ENSMUST00000236251.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr19_+_6451667 4.26 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr14_+_54441879 4.23 ENSMUST00000103726.2
T cell receptor alpha joining 15
chr13_+_23719579 4.22 ENSMUST00000080859.8
H3 clustered histone 8
chr9_-_83323080 4.19 ENSMUST00000034791.15
ENSMUST00000188548.7
ENSMUST00000034793.15
Leber congenital amaurosis 5 (human)
chr18_+_65933586 4.14 ENSMUST00000025394.14
ENSMUST00000236847.2
ENSMUST00000153193.3
SEC11 homolog C, signal peptidase complex subunit
chr5_+_31046670 3.88 ENSMUST00000200850.2
ATP/GTP binding protein-like 5
chr9_-_32255556 3.73 ENSMUST00000214223.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr13_+_74085916 3.72 ENSMUST00000222399.2
ENSMUST00000099384.4
bromodomain containing 9
chr2_-_26393826 3.69 ENSMUST00000028288.5
notch 1
chr7_+_24920840 3.55 ENSMUST00000055604.6
zinc finger protein 526
chr10_+_36850532 3.46 ENSMUST00000019911.14
ENSMUST00000105510.2
histone deacetylase 2
chr3_-_10273628 3.31 ENSMUST00000029041.6
fatty acid binding protein 4, adipocyte
chr12_-_4283926 3.28 ENSMUST00000111169.10
ENSMUST00000020981.12
centromere protein O
chr17_+_35220252 3.27 ENSMUST00000174260.8
valyl-tRNA synthetase
chr5_-_113910571 3.19 ENSMUST00000019118.8
squamous cell carcinoma antigen recognized by T cells 3
chr2_+_30176395 3.18 ENSMUST00000064447.12
nucleoporin 188
chr4_-_132191181 3.11 ENSMUST00000102567.4
mediator complex subunit 18
chr4_-_141553306 3.04 ENSMUST00000102481.4
chymotrypsin-like elastase family, member 2A
chr11_-_106890307 2.99 ENSMUST00000018506.13
karyopherin (importin) alpha 2
chr2_+_71617266 2.98 ENSMUST00000112101.8
ENSMUST00000028522.10
integrin alpha 6
chr1_-_179631190 2.88 ENSMUST00000027768.14
AT hook containing transcription factor 1
chr9_-_32255533 2.75 ENSMUST00000216033.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr7_+_97020810 2.68 ENSMUST00000098300.6
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr2_+_129435115 2.43 ENSMUST00000099113.10
ENSMUST00000103202.10
signal-regulatory protein alpha
chrX_-_36373910 2.36 ENSMUST00000076265.13
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_+_87295860 2.31 ENSMUST00000060835.12
testis expressed gene 14
chr11_+_6496875 2.28 ENSMUST00000000388.15
ENSMUST00000159007.8
cerebral cavernous malformation 2
chr7_+_24584076 2.23 ENSMUST00000153451.9
ENSMUST00000108429.8
ribosomal protein S19
chrX_+_161684563 2.19 ENSMUST00000112303.8
ENSMUST00000033727.14
cytidine 5'-triphosphate synthase 2
chr19_+_5416769 2.18 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr2_+_30176418 2.08 ENSMUST00000138666.8
ENSMUST00000113634.3
nucleoporin 188
chr11_+_108811168 2.03 ENSMUST00000052915.14
axin 2
chr5_-_25910788 2.01 ENSMUST00000030773.12
X-ray repair complementing defective repair in Chinese hamster cells 2
chr3_-_6685492 2.01 ENSMUST00000091364.4
RIKEN cDNA 1700008P02 gene
chr14_+_30741082 1.95 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chr4_+_44004437 1.92 ENSMUST00000107846.10
clathrin, light polypeptide (Lca)
chr7_+_97229065 1.92 ENSMUST00000107153.3
remodeling and spacing factor 1
chr14_+_76725876 1.91 ENSMUST00000101618.9
TSC22 domain family, member 1
chr8_-_106223502 1.89 ENSMUST00000212303.2
zinc finger, DHHC domain containing 1
chr4_-_58553553 1.89 ENSMUST00000107575.9
ENSMUST00000107574.8
ENSMUST00000147354.8
lysophosphatidic acid receptor 1
chr9_-_123507847 1.81 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_+_101508747 1.74 ENSMUST00000004949.8
TNF receptor-associated factor 6
chr8_+_18645543 1.73 ENSMUST00000146819.8
microcephaly, primary autosomal recessive 1
chr2_+_71617402 1.65 ENSMUST00000238991.2
integrin alpha 6
chr4_-_43562397 1.64 ENSMUST00000030187.14
talin 1
chr12_-_118162652 1.58 ENSMUST00000084806.7
dynein, axonemal, heavy chain 11
chr17_+_35200823 1.56 ENSMUST00000114011.11
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr10_-_62859626 1.53 ENSMUST00000119814.3
heterogeneous nuclear ribonucleoprotein H3
chr13_+_74086241 1.51 ENSMUST00000222749.2
bromodomain containing 9
chr4_-_58553311 1.50 ENSMUST00000107571.8
ENSMUST00000055018.11
lysophosphatidic acid receptor 1
chr11_-_106890195 1.43 ENSMUST00000106768.2
ENSMUST00000144834.8
karyopherin (importin) alpha 2
chrX_+_161684221 1.36 ENSMUST00000101095.9
cytidine 5'-triphosphate synthase 2
chr10_+_83558729 1.33 ENSMUST00000150459.3
RIKEN cDNA 1500009L16 gene
chr2_+_180961599 1.32 ENSMUST00000153112.2
regulator of telomere elongation helicase 1
chr1_-_60082246 1.32 ENSMUST00000027172.13
ENSMUST00000191251.7
islet cell autoantigen 1-like
chr15_-_98729333 1.28 ENSMUST00000168846.3
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr3_-_116456292 1.27 ENSMUST00000029570.9
major facilitator superfamily domain containing 14A
chr11_-_34048538 1.26 ENSMUST00000223852.2
RIKEN cDNA 4930469K13 gene
chr14_-_33700719 1.24 ENSMUST00000166737.2
zinc finger protein 488
chr17_+_88748139 1.20 ENSMUST00000112238.9
ENSMUST00000155640.2
forkhead box N2
chr1_-_74640504 1.19 ENSMUST00000136078.2
ENSMUST00000132081.2
ENSMUST00000113721.8
ENSMUST00000027357.12
ring finger protein 25
chr17_-_57338468 1.18 ENSMUST00000007814.10
ENSMUST00000233480.2
KH-type splicing regulatory protein
chr10_-_62859661 1.18 ENSMUST00000020263.14
ENSMUST00000118898.8
heterogeneous nuclear ribonucleoprotein H3
chr15_+_102314578 1.09 ENSMUST00000170884.8
ENSMUST00000163709.8
trans-acting transcription factor 1
chrX_+_104123367 1.01 ENSMUST00000119477.2
polysaccharide biosynthesis domain containing 1
chr5_+_30437579 0.95 ENSMUST00000145167.9
selenoprotein I
chr3_-_142587419 0.93 ENSMUST00000174422.8
ENSMUST00000173830.8
protein kinase N2
chrY_-_90850446 0.87 ENSMUST00000179623.2
predicted gene, 21748
chr14_-_54754810 0.86 ENSMUST00000023873.12
protein arginine N-methyltransferase 5
chr2_-_145776934 0.75 ENSMUST00000001818.5
crooked neck pre-mRNA splicing factor 1
chr4_-_44704006 0.66 ENSMUST00000146335.8
paired box 5
chr1_+_85822250 0.64 ENSMUST00000185569.2
integral membrane protein 2C
chrX_-_77627486 0.62 ENSMUST00000114025.8
ENSMUST00000134602.8
ENSMUST00000114024.9
proline rich Gla (G-carboxyglutamic acid) 1
chr7_-_16019379 0.53 ENSMUST00000174270.8
coiled-coil domain containing 9
chr3_+_89680867 0.53 ENSMUST00000038356.13
ubiquitin-conjugating enzyme E2Q family member 1
chrX_+_12454031 0.51 ENSMUST00000033313.3
ATPase, H+ transporting, lysosomal accessory protein 2
chr17_-_87332780 0.46 ENSMUST00000024957.7
phosphatidylinositol glycan anchor biosynthesis, class F
chr15_+_12824901 0.45 ENSMUST00000169061.8
drosha, ribonuclease type III
chr15_-_39807359 0.40 ENSMUST00000110305.3
low density lipoprotein-related protein 12
chrX_+_161684735 0.38 ENSMUST00000112302.8
ENSMUST00000112301.8
cytidine 5'-triphosphate synthase 2
chr14_+_55815580 0.35 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr7_-_16019935 0.32 ENSMUST00000145519.3
coiled-coil domain containing 9
chr10_+_17598961 0.31 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_9818601 0.30 ENSMUST00000057438.7
valosin containing protein (p97)/p47 complex interacting protein 1
chr8_-_70426910 0.26 ENSMUST00000116463.4
GATA zinc finger domain containing 2A
chr2_-_125993887 0.25 ENSMUST00000110448.3
ENSMUST00000110446.9
family with sequence similarity 227, member B
chr11_+_77928736 0.21 ENSMUST00000072289.12
ENSMUST00000100784.9
ENSMUST00000073660.7
flotillin 2
chrX_+_72386220 0.21 ENSMUST00000114499.8
ENSMUST00000033731.4
zinc finger protein 275
chr7_-_126859790 0.18 ENSMUST00000035276.5
dCTP pyrophosphatase 1
chr9_-_103243039 0.11 ENSMUST00000035484.11
carnitine deficiency-associated gene expressed in ventricle 3
chr4_-_58553171 0.10 ENSMUST00000145361.2
lysophosphatidic acid receptor 1
chr19_+_45991907 0.07 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chr2_+_129434834 0.06 ENSMUST00000103203.8
signal-regulatory protein alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
3.8 18.8 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
3.5 13.9 GO:1904008 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
3.1 12.5 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
3.0 15.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.7 8.0 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
2.5 15.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
2.3 9.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
2.2 46.8 GO:0070986 left/right axis specification(GO:0070986)
2.1 12.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.9 7.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.8 16.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.8 51.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
1.8 7.1 GO:1904430 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
1.6 17.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.5 14.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.4 12.5 GO:0007144 female meiosis I(GO:0007144)
1.3 11.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.3 9.0 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.2 15.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.2 12.1 GO:0035608 protein deglutamylation(GO:0035608)
1.1 4.6 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.1 11.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.1 11.3 GO:0014029 neural crest formation(GO:0014029)
1.1 19.4 GO:0015816 glycine transport(GO:0015816)
1.1 14.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.0 5.0 GO:0015074 DNA integration(GO:0015074)
1.0 40.5 GO:0051290 protein heterotetramerization(GO:0051290)
1.0 7.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.9 43.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.9 19.8 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.9 25.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.9 3.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.9 10.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.8 5.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.7 9.8 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.7 3.5 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.6 2.2 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.5 8.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5 19.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.5 5.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.5 4.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 1.9 GO:0016584 nucleosome positioning(GO:0016584)
0.5 15.4 GO:0006270 DNA replication initiation(GO:0006270)
0.5 21.4 GO:0051310 metaphase plate congression(GO:0051310)
0.5 4.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 21.9 GO:0006284 base-excision repair(GO:0006284)
0.4 4.6 GO:0000012 single strand break repair(GO:0000012)
0.4 1.9 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 4.6 GO:0035878 nail development(GO:0035878)
0.4 10.4 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.4 3.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.1 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.3 2.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.3 12.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 5.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.9 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3 3.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 3.9 GO:0051026 chiasma assembly(GO:0051026)
0.3 3.9 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.2 4.1 GO:0006465 signal peptide processing(GO:0006465)
0.2 32.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 6.2 GO:0031297 replication fork processing(GO:0031297)
0.2 2.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 3.3 GO:0034508 centromere complex assembly(GO:0034508)
0.2 3.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 4.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 28.8 GO:0007051 spindle organization(GO:0007051)
0.2 8.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.6 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 2.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 6.4 GO:0019835 cytolysis(GO:0019835)
0.1 3.0 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 4.7 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 11.0 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 4.2 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.5 GO:0048069 positive regulation of transforming growth factor beta1 production(GO:0032914) eye pigmentation(GO:0048069)
0.1 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 4.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.2 GO:0042262 DNA protection(GO:0042262)
0.1 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 4.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 6.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.7 GO:0021670 lateral ventricle development(GO:0021670)
0.0 23.7 GO:0051301 cell division(GO:0051301)
0.0 0.3 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 5.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 41.3 GO:0031262 Ndc80 complex(GO:0031262)
3.8 22.8 GO:0032133 chromosome passenger complex(GO:0032133)
2.4 21.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.2 17.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
2.2 12.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.0 13.9 GO:0005638 lamin filament(GO:0005638)
1.6 18.8 GO:0008278 cohesin complex(GO:0008278)
1.6 6.2 GO:0035101 FACT complex(GO:0035101)
1.5 21.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.4 8.5 GO:0031523 Myb complex(GO:0031523)
1.4 15.2 GO:0070531 BRCA1-A complex(GO:0070531)
1.3 9.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.2 11.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.2 7.0 GO:0070876 SOSS complex(GO:0070876)
1.1 3.2 GO:0071001 U4/U6 snRNP(GO:0071001)
1.0 13.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 10.2 GO:0042555 MCM complex(GO:0042555)
0.8 5.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.6 1.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.6 12.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 3.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 8.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 4.1 GO:0005787 signal peptidase complex(GO:0005787)
0.4 48.5 GO:0005930 axoneme(GO:0005930)
0.3 3.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 15.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 25.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 12.1 GO:0072686 mitotic spindle(GO:0072686)
0.2 51.4 GO:0000793 condensed chromosome(GO:0000793)
0.2 1.3 GO:0070847 core mediator complex(GO:0070847)
0.1 4.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 20.3 GO:0000922 spindle pole(GO:0000922)
0.1 19.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 5.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 12.5 GO:0005795 Golgi stack(GO:0005795)
0.1 1.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 5.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 12.0 GO:0032587 ruffle membrane(GO:0032587)
0.1 11.4 GO:0030315 T-tubule(GO:0030315)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 15.9 GO:0001650 fibrillar center(GO:0001650)
0.1 0.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.9 GO:0034709 methylosome(GO:0034709)
0.1 4.4 GO:0005643 nuclear pore(GO:0005643)
0.1 2.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 7.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 6.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 7.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 13.2 GO:0000785 chromatin(GO:0000785)
0.0 8.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.3 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.3 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 124.6 GO:0005634 nucleus(GO:0005634)
0.0 13.9 GO:0009986 cell surface(GO:0009986)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 17.9 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
4.2 12.5 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
3.9 27.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.8 11.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
3.3 19.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
3.1 21.9 GO:0000405 bubble DNA binding(GO:0000405)
3.0 9.1 GO:0003896 DNA primase activity(GO:0003896)
2.5 15.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
2.2 12.9 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.9 7.8 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.8 14.3 GO:0036310 annealing helicase activity(GO:0036310)
1.6 11.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.6 11.1 GO:0015616 DNA translocase activity(GO:0015616)
1.3 17.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.2 22.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.2 3.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
1.1 11.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 3.9 GO:0003883 CTP synthase activity(GO:0003883)
0.9 2.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.8 4.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 8.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 22.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 21.4 GO:0070840 dynein complex binding(GO:0070840)
0.5 3.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5 4.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.5 3.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.5 13.9 GO:0043274 phospholipase binding(GO:0043274)
0.5 4.6 GO:0038132 neuregulin binding(GO:0038132)
0.4 12.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 12.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 10.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 15.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 19.3 GO:0050699 WW domain binding(GO:0050699)
0.3 3.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.3 1.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 10.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 12.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 15.2 GO:0003684 damaged DNA binding(GO:0003684)
0.2 1.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 3.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 25.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 4.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 3.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 5.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 8.2 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 4.6 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 4.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 4.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 12.9 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 1.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 7.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 16.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 8.4 GO:0005518 collagen binding(GO:0005518)
0.1 2.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 6.8 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 8.1 GO:0042393 histone binding(GO:0042393)
0.0 3.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 5.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 5.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 7.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 10.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 32.4 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 49.4 PID ATM PATHWAY ATM pathway
1.1 60.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 8.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 4.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 22.3 PID E2F PATHWAY E2F transcription factor network
0.2 10.2 PID ATR PATHWAY ATR signaling pathway
0.2 27.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 11.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 6.2 ST GAQ PATHWAY G alpha q Pathway
0.2 4.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 13.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 9.9 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 3.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 3.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 14.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.5 23.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
1.5 19.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.4 17.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.2 28.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.2 25.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.9 9.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.8 17.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7 77.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.7 10.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.7 5.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6 10.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 15.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 8.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 32.8 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.3 11.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 17.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 11.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 4.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.2 1.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 3.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 3.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 5.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 3.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 6.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 4.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 4.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 7.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 8.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 3.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis