ISMARA results: Egr1

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Egr1

Z-value: 1.94

Motif logo

Transcription factors associated with Egr1

Gene Symbol	Gene ID	Gene Info
Egr1 Ensembl NCBI MGI UniProt	ENSMUSG00000038418.8	Egr1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Egr1	mm39_v1_chr18_+_34994253_34994268	0.71	4.4e-12	Click!

Activity profile of Egr1 motif

Sorted Z-values of Egr1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr11_-_6015538 Show fit	22.10	ENSMUST00000101585.10 ENSMUST00000066431.14 ENSMUST00000109815.9 ENSMUST00000109812.9 ENSMUST00000101586.3 ENSMUST00000093355.12 ENSMUST00000019133.11	Camk2b Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II, beta
chr10_-_108846816 Show fit	19.90	ENSMUST00000105276.8 ENSMUST00000064054.14	Syt1 Ensembl NCBI MGI UniProt Show fit	synaptotagmin I
chrX_-_20787150 Show fit	19.84	ENSMUST00000081893.7 ENSMUST00000115345.8	Syn1 Ensembl NCBI MGI UniProt Show fit	synapsin I
chr4_+_127062924 Show fit	19.74	ENSMUST00000046659.14	Dlgap3 Ensembl NCBI MGI UniProt Show fit	DLG associated protein 3
chr9_-_37464200 Show fit	19.65	ENSMUST00000065668.12	Nrgn Ensembl NCBI MGI UniProt Show fit	neurogranin
chrX_+_7504913 Show fit	16.93	ENSMUST00000128890.2	Syp Ensembl NCBI MGI UniProt Show fit	synaptophysin
chr6_-_60805873 Show fit	16.90	ENSMUST00000114268.5	Snca Ensembl NCBI MGI UniProt Show fit	synuclein, alpha
chr5_-_139115914 Show fit	14.87	ENSMUST00000129851.8	Prkar1b Ensembl NCBI MGI UniProt Show fit	protein kinase, cAMP dependent regulatory, type I beta
chr5_+_137551774 Show fit	14.49	ENSMUST00000136088.8 ENSMUST00000139395.8	Actl6b Ensembl NCBI MGI UniProt Show fit	actin-like 6B
chr5_-_139115417 Show fit	14.02	ENSMUST00000026973.14	Prkar1b Ensembl NCBI MGI UniProt Show fit	protein kinase, cAMP dependent regulatory, type I beta
chrX_+_35459621 Show fit	13.94	ENSMUST00000115256.2	Zcchc12 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 12
chr2_+_158452651 Show fit	13.23	ENSMUST00000045738.5	Slc32a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 32 (GABA vesicular transporter), member 1
chr4_+_42917228 Show fit	12.94	ENSMUST00000107976.9 ENSMUST00000069184.9	Phf24 Ensembl NCBI MGI UniProt Show fit	PHD finger protein 24
chr6_+_117988399 Show fit	12.72	ENSMUST00000164960.4	Rasgef1a Ensembl NCBI MGI UniProt Show fit	RasGEF domain family, member 1A
chr16_-_34334314 Show fit	12.31	ENSMUST00000151491.8 ENSMUST00000114960.9	Kalrn Ensembl NCBI MGI UniProt Show fit	kalirin, RhoGEF kinase
chr12_+_108300599 Show fit	12.19	ENSMUST00000021684.6	Cyp46a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 46, subfamily a, polypeptide 1
chr7_-_46782448 Show fit	11.97	ENSMUST00000033142.13	Ptpn5 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 5
chr15_-_44978223 Show fit	11.81	ENSMUST00000022967.7	Kcnv1 Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily V, member 1
chr10_-_127099183 Show fit	11.62	ENSMUST00000099172.5	Kif5a Ensembl NCBI MGI UniProt Show fit	kinesin family member 5A
chr5_+_137059127 Show fit	11.58	ENSMUST00000041543.9 ENSMUST00000186451.2	Vgf Ensembl NCBI MGI UniProt Show fit	VGF nerve growth factor inducible
chr11_-_97464866 Show fit	11.35	ENSMUST00000207653.2 ENSMUST00000107593.8	Srcin1 Ensembl NCBI MGI UniProt Show fit	SRC kinase signaling inhibitor 1
chr8_+_96404713 Show fit	11.31	ENSMUST00000041318.14	Ndrg4 Ensembl NCBI MGI UniProt Show fit	N-myc downstream regulated gene 4
chr1_-_189075903 Show fit	11.18	ENSMUST00000192723.2 ENSMUST00000110920.7	Kcnk2 Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily K, member 2
chr16_-_34334454 Show fit	11.18	ENSMUST00000089655.12	Kalrn Ensembl NCBI MGI UniProt Show fit	kalirin, RhoGEF kinase
chr7_-_27095964 Show fit	11.11	ENSMUST00000108363.8	Sptbn4 Ensembl NCBI MGI UniProt Show fit	spectrin beta, non-erythrocytic 4
chr5_+_137551790 Show fit	10.78	ENSMUST00000136565.8 ENSMUST00000149292.8 ENSMUST00000125489.2	Actl6b Ensembl NCBI MGI UniProt Show fit	actin-like 6B
chr9_+_20943350 Show fit	10.74	ENSMUST00000019616.6	Icam5 Ensembl NCBI MGI UniProt Show fit	intercellular adhesion molecule 5, telencephalin
chr9_+_60620272 Show fit	10.28	ENSMUST00000038407.6	Larp6 Ensembl NCBI MGI UniProt Show fit	La ribonucleoprotein domain family, member 6
chr11_+_69231274 Show fit	10.11	ENSMUST00000129321.2	Rnf227 Ensembl NCBI MGI UniProt Show fit	ring finger protein 227
chr10_-_116309764 Show fit	10.03	ENSMUST00000068233.11	Kcnmb4 Ensembl NCBI MGI UniProt Show fit	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr6_-_113911640 Show fit	9.98	ENSMUST00000101044.9	Atp2b2 Ensembl NCBI MGI UniProt Show fit	ATPase, Ca++ transporting, plasma membrane 2
chr15_-_74544409 Show fit	9.81	ENSMUST00000023268.14 ENSMUST00000110009.4	Arc Ensembl NCBI MGI UniProt Show fit	activity regulated cytoskeletal-associated protein
chrX_-_72703330 Show fit	9.78	ENSMUST00000114473.8 ENSMUST00000002087.14	Pnck Ensembl NCBI MGI UniProt Show fit	pregnancy upregulated non-ubiquitously expressed CaM kinase
chr8_-_125161061 Show fit	9.77	ENSMUST00000140012.8	Pgbd5 Ensembl NCBI MGI UniProt Show fit	piggyBac transposable element derived 5
chr11_+_80367839 Show fit	9.72	ENSMUST00000053413.12 ENSMUST00000147694.2	Cdk5r1 Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr4_-_126647156 Show fit	9.56	ENSMUST00000030637.14 ENSMUST00000106116.2	Ncdn Ensembl NCBI MGI UniProt Show fit	neurochondrin
chrX_-_72703652 Show fit	9.47	ENSMUST00000114472.8	Pnck Ensembl NCBI MGI UniProt Show fit	pregnancy upregulated non-ubiquitously expressed CaM kinase
chr15_-_66158445 Show fit	9.38	ENSMUST00000070256.9	Kcnq3 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, subfamily Q, member 3
chr7_-_45016138 Show fit	9.34	ENSMUST00000211067.2 ENSMUST00000003961.16	Ppfia3 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_-_189075515 Show fit	9.26	ENSMUST00000193319.6	Kcnk2 Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily K, member 2
chr3_-_89230190 Show fit	9.15	ENSMUST00000200436.2 ENSMUST00000029673.10	Efna3 Ensembl NCBI MGI UniProt Show fit	ephrin A3
chr10_-_79975181 Show fit	9.09	ENSMUST00000105369.8	Cbarp Ensembl NCBI MGI UniProt Show fit	calcium channel, voltage-dependent, beta subunit associated regulatory protein
chr7_+_81824544 Show fit	8.95	ENSMUST00000032874.14	Sh3gl3 Ensembl NCBI MGI UniProt Show fit	SH3-domain GRB2-like 3
chr10_+_79552421 Show fit	8.93	ENSMUST00000099513.8 ENSMUST00000020581.3	Hcn2 Ensembl NCBI MGI UniProt Show fit	hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr7_+_29991101 Show fit	8.92	ENSMUST00000150892.2 ENSMUST00000126216.2 ENSMUST00000014065.16	Clip3 Ensembl NCBI MGI UniProt Show fit	CAP-GLY domain containing linker protein 3
chr13_-_12121831 Show fit	8.89	ENSMUST00000021750.15 ENSMUST00000170156.3 ENSMUST00000220597.2	Ryr2 Ensembl NCBI MGI UniProt Show fit	ryanodine receptor 2, cardiac
chr2_+_157756535 Show fit	8.88	ENSMUST00000109523.2	Vstm2l Ensembl NCBI MGI UniProt Show fit	V-set and transmembrane domain containing 2-like
chr11_-_118460736 Show fit	8.88	ENSMUST00000136551.3	Rbfox3 Ensembl NCBI MGI UniProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 3
chr7_-_25374472 Show fit	8.68	ENSMUST00000108404.8 ENSMUST00000108405.2 ENSMUST00000079439.10	Tmem91 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 91
chr11_+_69231589 Show fit	8.65	ENSMUST00000218008.2 ENSMUST00000151617.3	Rnf227 Ensembl NCBI MGI UniProt Show fit	ring finger protein 227
chr14_-_76794103 Show fit	8.65	ENSMUST00000064517.9 ENSMUST00000228055.2	Serp2 Ensembl NCBI MGI UniProt Show fit	stress-associated endoplasmic reticulum protein family member 2
chr7_+_99876515 Show fit	8.60	ENSMUST00000084935.11	Pgm2l1 Ensembl NCBI MGI UniProt Show fit	phosphoglucomutase 2-like 1
chrX_+_35459557 Show fit	8.51	ENSMUST00000115258.9	Zcchc12 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 12
chr9_-_112016966 Show fit	8.51	ENSMUST00000178410.2 ENSMUST00000172380.10	Arpp21 Ensembl NCBI MGI UniProt Show fit	cyclic AMP-regulated phosphoprotein, 21
chr2_-_167030706 Show fit	8.49	ENSMUST00000207917.2	Kcnb1 Ensembl NCBI MGI UniProt Show fit	potassium voltage gated channel, Shab-related subfamily, member 1
chrX_+_35459589 Show fit	8.46	ENSMUST00000048067.10	Zcchc12 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 12
chr14_-_70873385 Show fit	8.43	ENSMUST00000228295.2 ENSMUST00000022695.16	Dmtn Ensembl NCBI MGI UniProt Show fit	dematin actin binding protein
chrX_+_35459601 Show fit	8.26	ENSMUST00000115257.8	Zcchc12 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 12
chr12_+_108602008 Show fit	8.23	ENSMUST00000172409.2	Evl Ensembl NCBI MGI UniProt Show fit	Ena-vasodilator stimulated phosphoprotein
chr5_-_115332343 Show fit	8.21	ENSMUST00000112113.8	Cabp1 Ensembl NCBI MGI UniProt Show fit	calcium binding protein 1
chr9_-_89620461 Show fit	8.21	ENSMUST00000060700.4 ENSMUST00000185470.3	Ankrd34c Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 34C
chr9_+_58489523 Show fit	8.07	ENSMUST00000177292.8 ENSMUST00000085651.12 ENSMUST00000176557.8 ENSMUST00000114121.11 ENSMUST00000177064.8	Nptn Ensembl NCBI MGI UniProt Show fit	neuroplastin
chr15_+_100768806 Show fit	8.05	ENSMUST00000201549.4 ENSMUST00000108908.6	Scn8a Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type VIII, alpha
chr11_-_97464755 Show fit	8.01	ENSMUST00000126287.2 ENSMUST00000107590.9	Srcin1 Ensembl NCBI MGI UniProt Show fit	SRC kinase signaling inhibitor 1
chr11_+_69909245 Show fit	7.99	ENSMUST00000231415.2 ENSMUST00000108588.9	Dlg4 Ensembl NCBI MGI UniProt Show fit	discs large MAGUK scaffold protein 4
chr13_+_83672965 Show fit	7.93	ENSMUST00000199432.5 ENSMUST00000198069.5 ENSMUST00000197681.5 ENSMUST00000197722.5 ENSMUST00000197938.5	Mef2c Ensembl NCBI MGI UniProt Show fit	myocyte enhancer factor 2C
chr3_+_96503944 Show fit	7.89	ENSMUST00000058943.8	Ankrd34a Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 34A
chr16_+_20408886 Show fit	7.84	ENSMUST00000232279.2 ENSMUST00000232474.2	Vwa5b2 Ensembl NCBI MGI UniProt Show fit	von Willebrand factor A domain containing 5B2
chr2_+_156455583 Show fit	7.83	ENSMUST00000109567.10 ENSMUST00000169464.9	Dlgap4 Ensembl NCBI MGI UniProt Show fit	DLG associated protein 4
chr5_-_108515740 Show fit	7.83	ENSMUST00000197216.3	Gm42517 Ensembl NCBI MGI UniProt Show fit	predicted gene 42517
chr1_+_66507523 Show fit	7.74	ENSMUST00000061620.17 ENSMUST00000212557.3	Unc80 Ensembl NCBI MGI UniProt Show fit	unc-80, NALCN activator
chr12_+_108601963 Show fit	7.73	ENSMUST00000223109.2	Evl Ensembl NCBI MGI UniProt Show fit	Ena-vasodilator stimulated phosphoprotein
chr15_-_78428865 Show fit	7.73	ENSMUST00000053239.4	Sstr3 Ensembl NCBI MGI UniProt Show fit	somatostatin receptor 3
chr15_+_89383799 Show fit	7.66	ENSMUST00000109309.9	Shank3 Ensembl NCBI MGI UniProt Show fit	SH3 and multiple ankyrin repeat domains 3
chr9_-_102231884 Show fit	7.66	ENSMUST00000035129.14 ENSMUST00000085169.12 ENSMUST00000149800.3	Ephb1 Ensembl NCBI MGI UniProt Show fit	Eph receptor B1
chr16_-_18448614 Show fit	7.63	ENSMUST00000231956.2 ENSMUST00000096987.7	Septin5 Ensembl NCBI MGI UniProt Show fit	septin 5
chr5_-_5430172 Show fit	7.62	ENSMUST00000030763.13	Cdk14 Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 14
chr11_-_75686874 Show fit	7.61	ENSMUST00000021209.8	Doc2b Ensembl NCBI MGI UniProt Show fit	double C2, beta
chr16_+_94171477 Show fit	7.60	ENSMUST00000117648.9 ENSMUST00000147352.8 ENSMUST00000150346.8 ENSMUST00000155692.8 ENSMUST00000153988.9 ENSMUST00000139513.9 ENSMUST00000141856.8 ENSMUST00000152117.8 ENSMUST00000150097.8 ENSMUST00000122895.8 ENSMUST00000151770.8 ENSMUST00000231569.2 ENSMUST00000147046.8 ENSMUST00000149885.8 ENSMUST00000127667.8 ENSMUST00000119131.3 ENSMUST00000145883.2	Ttc3 Ensembl NCBI MGI UniProt Show fit	tetratricopeptide repeat domain 3
chrX_-_7440480 Show fit	7.52	ENSMUST00000115742.9 ENSMUST00000150787.8	Ppp1r3f Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 3F
chr10_-_81308693 Show fit	7.42	ENSMUST00000147524.3 ENSMUST00000119060.8	Celf5 Ensembl NCBI MGI UniProt Show fit	CUGBP, Elav-like family member 5
chr5_+_137059522 Show fit	7.41	ENSMUST00000187382.2	Vgf Ensembl NCBI MGI UniProt Show fit	VGF nerve growth factor inducible
chr16_-_20440005 Show fit	7.39	ENSMUST00000052939.4	Camk2n2 Ensembl NCBI MGI UniProt Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr3_-_86827640 Show fit	7.32	ENSMUST00000195561.6	Dclk2 Ensembl NCBI MGI UniProt Show fit	doublecortin-like kinase 2
chr12_-_76756772 Show fit	7.29	ENSMUST00000166101.2	Sptb Ensembl NCBI MGI UniProt Show fit	spectrin beta, erythrocytic
chr9_-_20657643 Show fit	7.25	ENSMUST00000215999.2	Olfm2 Ensembl NCBI MGI UniProt Show fit	olfactomedin 2
chr5_+_9316097 Show fit	7.14	ENSMUST00000134991.8 ENSMUST00000069538.14 ENSMUST00000115348.9	Elapor2 Ensembl NCBI MGI UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr2_+_143388062 Show fit	7.12	ENSMUST00000028905.10	Pcsk2 Ensembl NCBI MGI UniProt Show fit	proprotein convertase subtilisin/kexin type 2
chr15_+_81119700 Show fit	7.11	ENSMUST00000166855.3	Mchr1 Ensembl NCBI MGI UniProt Show fit	melanin-concentrating hormone receptor 1
chr15_+_100768776 Show fit	7.08	ENSMUST00000108909.9	Scn8a Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type VIII, alpha
chr5_+_120787253 Show fit	6.90	ENSMUST00000156722.2	Rasal1 Ensembl NCBI MGI UniProt Show fit	RAS protein activator like 1 (GAP1 like)
chr7_+_122270599 Show fit	6.78	ENSMUST00000182563.2	Cacng3 Ensembl NCBI MGI UniProt Show fit	calcium channel, voltage-dependent, gamma subunit 3
chr7_+_26958150 Show fit	6.76	ENSMUST00000079258.7	Numbl Ensembl NCBI MGI UniProt Show fit	numb-like
chrX_+_5959507 Show fit	6.72	ENSMUST00000103007.4	Nudt11 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_+_5100475 Show fit	6.69	ENSMUST00000225427.2	Rin1 Ensembl NCBI MGI UniProt Show fit	Ras and Rab interactor 1
chr1_-_79836344 Show fit	6.64	ENSMUST00000027467.11	Serpine2 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade E, member 2
chr11_-_97944239 Show fit	6.63	ENSMUST00000017544.9	Stac2 Ensembl NCBI MGI UniProt Show fit	SH3 and cysteine rich domain 2
chr13_+_55517545 Show fit	6.57	ENSMUST00000063771.14	Rgs14 Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 14
chr14_-_20596580 Show fit	6.48	ENSMUST00000022355.11 ENSMUST00000161445.8 ENSMUST00000159027.8	Ppp3cb Ensembl NCBI MGI UniProt Show fit	protein phosphatase 3, catalytic subunit, beta isoform
chr11_-_78388560 Show fit	6.47	ENSMUST00000061174.7	Sarm1 Ensembl NCBI MGI UniProt Show fit	sterile alpha and HEAT/Armadillo motif containing 1
chr13_-_54897660 Show fit	6.44	ENSMUST00000135343.2	Gprin1 Ensembl NCBI MGI UniProt Show fit	G protein-regulated inducer of neurite outgrowth 1
chr7_+_122270623 Show fit	6.42	ENSMUST00000182095.2	Cacng3 Ensembl NCBI MGI UniProt Show fit	calcium channel, voltage-dependent, gamma subunit 3
chr11_-_103844870 Show fit	6.41	ENSMUST00000103075.11	Nsf Ensembl NCBI MGI UniProt Show fit	N-ethylmaleimide sensitive fusion protein
chr13_-_54897425 Show fit	6.41	ENSMUST00000099506.2	Gprin1 Ensembl NCBI MGI UniProt Show fit	G protein-regulated inducer of neurite outgrowth 1
chr13_-_69147639 Show fit	6.39	ENSMUST00000022013.8	Adcy2 Ensembl NCBI MGI UniProt Show fit	adenylate cyclase 2
chr13_-_10410857 Show fit	6.31	ENSMUST00000187510.7	Chrm3 Ensembl NCBI MGI UniProt Show fit	cholinergic receptor, muscarinic 3, cardiac
chr12_+_44375665 Show fit	6.28	ENSMUST00000110748.4	Nrcam Ensembl NCBI MGI UniProt Show fit	neuronal cell adhesion molecule
chr11_-_78388284 Show fit	6.21	ENSMUST00000108287.10	Sarm1 Ensembl NCBI MGI UniProt Show fit	sterile alpha and HEAT/Armadillo motif containing 1
chr2_+_81883566 Show fit	6.18	ENSMUST00000047527.8	Zfp804a Ensembl NCBI MGI UniProt Show fit	zinc finger protein 804A
chr11_-_4696778 Show fit	6.17	ENSMUST00000009219.3	Cabp7 Ensembl NCBI MGI UniProt Show fit	calcium binding protein 7
chr2_-_25209107 Show fit	6.17	ENSMUST00000114318.10 ENSMUST00000114310.10 ENSMUST00000114308.10 ENSMUST00000114317.10 ENSMUST00000028335.13 ENSMUST00000114314.10 ENSMUST00000114307.8	Grin1 Ensembl NCBI MGI UniProt Show fit	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chrX_+_7744535 Show fit	6.13	ENSMUST00000033495.15	Pim2 Ensembl NCBI MGI UniProt Show fit	proviral integration site 2
chr16_-_18448454 Show fit	6.12	ENSMUST00000231622.2	Septin5 Ensembl NCBI MGI UniProt Show fit	septin 5
chrX_-_58179754 Show fit	6.01	ENSMUST00000033473.12	Fgf13 Ensembl NCBI MGI UniProt Show fit	fibroblast growth factor 13
chr7_+_126550009 Show fit	6.01	ENSMUST00000106332.3	Sez6l2 Ensembl NCBI MGI UniProt Show fit	seizure related 6 homolog like 2
chr17_+_25946644 Show fit	5.89	ENSMUST00000237183.2 ENSMUST00000237785.2 ENSMUST00000047273.3	Rpusd1 Ensembl NCBI MGI UniProt Show fit	RNA pseudouridylate synthase domain containing 1
chr2_-_24653059 Show fit	5.84	ENSMUST00000100348.10 ENSMUST00000041342.12 ENSMUST00000114447.8 ENSMUST00000102939.9 ENSMUST00000070864.14	Cacna1b Ensembl NCBI MGI UniProt Show fit	calcium channel, voltage-dependent, N type, alpha 1B subunit
chr14_-_33169099 Show fit	5.80	ENSMUST00000111944.10 ENSMUST00000022504.12 ENSMUST00000111945.9	Mapk8 Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase 8
chr11_+_69909659 Show fit	5.78	ENSMUST00000232002.2 ENSMUST00000134376.10 ENSMUST00000231221.2	Dlg4 Ensembl NCBI MGI UniProt Show fit	discs large MAGUK scaffold protein 4
chr3_-_152373997 Show fit	5.74	ENSMUST00000045262.11	Ak5 Ensembl NCBI MGI UniProt Show fit	adenylate kinase 5
chr3_+_136376440 Show fit	5.71	ENSMUST00000056758.9	Ppp3ca Ensembl NCBI MGI UniProt Show fit	protein phosphatase 3, catalytic subunit, alpha isoform
chr16_+_80997580 Show fit	5.71	ENSMUST00000037785.14 ENSMUST00000067602.5	Ncam2 Ensembl NCBI MGI UniProt Show fit	neural cell adhesion molecule 2
chr16_+_4964849 Show fit	5.70	ENSMUST00000165810.2 ENSMUST00000230616.2	Sec14l5 Ensembl NCBI MGI UniProt Show fit	SEC14-like lipid binding 5
chr9_-_112016834 Show fit	5.67	ENSMUST00000111872.9 ENSMUST00000164754.9	Arpp21 Ensembl NCBI MGI UniProt Show fit	cyclic AMP-regulated phosphoprotein, 21
chr18_+_86413077 Show fit	5.63	ENSMUST00000058829.4	Neto1 Ensembl NCBI MGI UniProt Show fit	neuropilin (NRP) and tolloid (TLL)-like 1
chr13_+_83672708 Show fit	5.58	ENSMUST00000199105.5	Mef2c Ensembl NCBI MGI UniProt Show fit	myocyte enhancer factor 2C
chr7_-_126303947 Show fit	5.55	ENSMUST00000032949.14	Coro1a Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr15_+_100768551 Show fit	5.49	ENSMUST00000082209.13	Scn8a Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type VIII, alpha
chr17_-_56447332 Show fit	5.49	ENSMUST00000001256.11	Sema6b Ensembl NCBI MGI UniProt Show fit	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_-_115258508 Show fit	5.45	ENSMUST00000044152.13 ENSMUST00000106542.9	Hid1 Ensembl NCBI MGI UniProt Show fit	HID1 domain containing
chr6_+_85164420 Show fit	5.41	ENSMUST00000045942.9	Emx1 Ensembl NCBI MGI UniProt Show fit	empty spiracles homeobox 1
chr6_-_126621751 Show fit	5.40	ENSMUST00000055168.5	Kcna1 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, shaker-related subfamily, member 1
chr9_+_21077010 Show fit	5.40	ENSMUST00000039413.15	Pde4a Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 4A, cAMP specific
chr7_+_29991366 Show fit	5.36	ENSMUST00000144508.2	Clip3 Ensembl NCBI MGI UniProt Show fit	CAP-GLY domain containing linker protein 3
chr2_-_118534444 Show fit	5.35	ENSMUST00000104937.2	Ankrd63 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 63
chr11_-_100246209 Show fit	5.26	ENSMUST00000146878.3	Hap1 Ensembl NCBI MGI UniProt Show fit	huntingtin-associated protein 1
chr6_-_126621770 Show fit	5.24	ENSMUST00000203094.2	Kcna1 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, shaker-related subfamily, member 1
chr4_+_42949814 Show fit	5.23	ENSMUST00000037872.10 ENSMUST00000098112.9	Dnajb5 Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B5
chr15_+_99122742 Show fit	5.17	ENSMUST00000041415.5	Kcnh3 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_+_119833589 Show fit	5.14	ENSMUST00000106231.8 ENSMUST00000075180.12 ENSMUST00000103021.10 ENSMUST00000026436.10 ENSMUST00000106233.2	Baiap2 Ensembl NCBI MGI UniProt Show fit	brain-specific angiogenesis inhibitor 1-associated protein 2
chr12_-_32111214 Show fit	5.09	ENSMUST00000003079.12 ENSMUST00000036497.16	Prkar2b Ensembl NCBI MGI UniProt Show fit	protein kinase, cAMP dependent regulatory, type II beta
chr7_+_28151370 Show fit	5.09	ENSMUST00000190954.7	Lrfn1 Ensembl NCBI MGI UniProt Show fit	leucine rich repeat and fibronectin type III domain containing 1
chr7_-_62862261 Show fit	5.05	ENSMUST00000032738.7	Chrna7 Ensembl NCBI MGI UniProt Show fit	cholinergic receptor, nicotinic, alpha polypeptide 7
chr12_+_102915102 Show fit	5.01	ENSMUST00000101099.12	Unc79 Ensembl NCBI MGI UniProt Show fit	unc-79 homolog
chr7_-_126303351 Show fit	4.96	ENSMUST00000106364.8	Coro1a Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr11_+_68979308 Show fit	4.83	ENSMUST00000021273.13	Vamp2 Ensembl NCBI MGI UniProt Show fit	vesicle-associated membrane protein 2
chr2_+_164328763 Show fit	4.80	ENSMUST00000109349.9	Dbndd2 Ensembl NCBI MGI UniProt Show fit	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_97520511 Show fit	4.80	ENSMUST00000052281.6	Epop Ensembl NCBI MGI UniProt Show fit	elongin BC and polycomb repressive complex 2 associated protein
chr4_-_47474283 Show fit	4.77	ENSMUST00000044148.3	Alg2 Ensembl NCBI MGI UniProt Show fit	asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)
chr5_-_31453206 Show fit	4.74	ENSMUST00000041266.11 ENSMUST00000172435.8 ENSMUST00000201417.2	Fndc4 Ensembl NCBI MGI UniProt Show fit	fibronectin type III domain containing 4
chr5_+_100187844 Show fit	4.69	ENSMUST00000169390.8 ENSMUST00000031268.8	Enoph1 Ensembl NCBI MGI UniProt Show fit	enolase-phosphatase 1
chr7_-_37806912 Show fit	4.63	ENSMUST00000108023.10	Ccne1 Ensembl NCBI MGI UniProt Show fit	cyclin E1
chr7_+_43474819 Show fit	4.63	ENSMUST00000107967.3	Klk6 Ensembl NCBI MGI UniProt Show fit	kallikrein related-peptidase 6
chr2_+_145009625 Show fit	4.61	ENSMUST00000110007.8	Slc24a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr3_-_89000591 Show fit	4.59	ENSMUST00000090929.12 ENSMUST00000052539.13	Rusc1 Ensembl NCBI MGI UniProt Show fit	RUN and SH3 domain containing 1
chr13_+_83672654 Show fit	4.52	ENSMUST00000199019.5	Mef2c Ensembl NCBI MGI UniProt Show fit	myocyte enhancer factor 2C
chr7_-_142213219 Show fit	4.50	ENSMUST00000121128.8	Igf2 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 2
chr3_+_28317570 Show fit	4.47	ENSMUST00000160307.9 ENSMUST00000159680.9 ENSMUST00000160518.8 ENSMUST00000162485.8 ENSMUST00000159308.8 ENSMUST00000162777.8 ENSMUST00000161964.2	Tnik Ensembl NCBI MGI UniProt Show fit	TRAF2 and NCK interacting kinase
chr2_+_149672708 Show fit	4.45	ENSMUST00000109935.8	Syndig1 Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1
chr6_-_120470768 Show fit	4.42	ENSMUST00000178687.2	Tmem121b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 121B
chr18_-_20879461 Show fit	4.40	ENSMUST00000070080.6	B4galt6 Ensembl NCBI MGI UniProt Show fit	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
chr19_-_50667079 Show fit	4.39	ENSMUST00000209413.2 ENSMUST00000072685.13 ENSMUST00000164039.9	Sorcs1 Ensembl NCBI MGI UniProt Show fit	sortilin-related VPS10 domain containing receptor 1
chr6_+_85408953 Show fit	4.36	ENSMUST00000045693.8	Smyd5 Ensembl NCBI MGI UniProt Show fit	SET and MYND domain containing 5
chr12_+_80509978 Show fit	4.35	ENSMUST00000219272.2	Exd2 Ensembl NCBI MGI UniProt Show fit	exonuclease 3'-5' domain containing 2
chr7_+_128290204 Show fit	4.33	ENSMUST00000118605.2	Inpp5f Ensembl NCBI MGI UniProt Show fit	inositol polyphosphate-5-phosphatase F
chr13_-_105430932 Show fit	4.30	ENSMUST00000224662.2	Rnf180 Ensembl NCBI MGI UniProt Show fit	ring finger protein 180
chr15_-_64184485 Show fit	4.30	ENSMUST00000177083.8 ENSMUST00000177371.8	Asap1 Ensembl NCBI MGI UniProt Show fit	ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr8_-_69187708 Show fit	4.26	ENSMUST00000136060.8 ENSMUST00000130214.8 ENSMUST00000078350.13	Csgalnact1 Ensembl NCBI MGI UniProt Show fit	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr4_-_151946219 Show fit	4.26	ENSMUST00000097774.9	Camta1 Ensembl NCBI MGI UniProt Show fit	calmodulin binding transcription activator 1
chr8_-_122305486 Show fit	4.14	ENSMUST00000212985.2 ENSMUST00000059018.14	Fbxo31 Ensembl NCBI MGI UniProt Show fit	F-box protein 31
chr15_+_87509413 Show fit	4.12	ENSMUST00000068088.8	Tafa5 Ensembl NCBI MGI UniProt Show fit	TAFA chemokine like family member 5
chr6_+_4747298 Show fit	4.11	ENSMUST00000166678.2 ENSMUST00000176204.8	Peg10 Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chr2_+_149672814 Show fit	4.08	ENSMUST00000137280.2 ENSMUST00000149705.2	Syndig1 Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1
chr19_+_23736205 Show fit	4.06	ENSMUST00000025830.9	Apba1 Ensembl NCBI MGI UniProt Show fit	amyloid beta (A4) precursor protein binding, family A, member 1
chr12_+_102915709 Show fit	4.05	ENSMUST00000179002.8	Unc79 Ensembl NCBI MGI UniProt Show fit	unc-79 homolog
chr7_-_16007542 Show fit	4.01	ENSMUST00000169612.3	Inafm1 Ensembl NCBI MGI UniProt Show fit	InaF motif containing 1
chr19_-_5135510 Show fit	4.00	ENSMUST00000140389.8 ENSMUST00000151413.2 ENSMUST00000077066.8	Tmem151a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 151A
chr11_-_72026547 Show fit	3.99	ENSMUST00000108508.3 ENSMUST00000075258.13	Pitpnm3 Ensembl NCBI MGI UniProt Show fit	PITPNM family member 3
chr13_-_105430889 Show fit	3.99	ENSMUST00000226044.2	Rnf180 Ensembl NCBI MGI UniProt Show fit	ring finger protein 180
chr13_-_43457626 Show fit	3.99	ENSMUST00000055341.7	Gfod1 Ensembl NCBI MGI UniProt Show fit	glucose-fructose oxidoreductase domain containing 1
chr2_+_116951855 Show fit	3.98	ENSMUST00000028829.13	Spred1 Ensembl NCBI MGI UniProt Show fit	sprouty protein with EVH-1 domain 1, related sequence
chr7_+_44240310 Show fit	3.85	ENSMUST00000107906.6	Kcnc3 Ensembl NCBI MGI UniProt Show fit	potassium voltage gated channel, Shaw-related subfamily, member 3
chr14_+_84680993 Show fit	3.82	ENSMUST00000071370.7	Pcdh17 Ensembl NCBI MGI UniProt Show fit	protocadherin 17
chr14_+_54713557 Show fit	3.82	ENSMUST00000164766.8	Rem2 Ensembl NCBI MGI UniProt Show fit	rad and gem related GTP binding protein 2
chr10_+_83558729 Show fit	3.77	ENSMUST00000150459.3	1500009L16Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1500009L16 gene
chr1_+_60448813 Show fit	3.77	ENSMUST00000188594.7 ENSMUST00000188618.7 ENSMUST00000189980.7	Abi2 Ensembl NCBI MGI UniProt Show fit	abl interactor 2
chr1_-_74544946 Show fit	3.72	ENSMUST00000044260.11 ENSMUST00000186282.7	Usp37 Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 37
chr12_+_105302853 Show fit	3.71	ENSMUST00000180458.9	Tunar Ensembl NCBI MGI UniProt Show fit	Tcl1 upstream neural differentiation associated RNA
chr17_+_8744201 Show fit	3.69	ENSMUST00000115715.8	Pde10a Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 10A
chr2_-_25209199 Show fit	3.66	ENSMUST00000114312.2	Grin1 Ensembl NCBI MGI UniProt Show fit	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr8_+_40876827 Show fit	3.64	ENSMUST00000049389.11 ENSMUST00000128166.8 ENSMUST00000167766.2	Zdhhc2 Ensembl NCBI MGI UniProt Show fit	zinc finger, DHHC domain containing 2
chr1_-_52272370 Show fit	3.64	ENSMUST00000114513.9 ENSMUST00000114510.8	Gls Ensembl NCBI MGI UniProt Show fit	glutaminase
chr6_+_99669640 Show fit	3.63	ENSMUST00000101122.3	Gpr27 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 27
chr11_-_86648309 Show fit	3.63	ENSMUST00000060766.16 ENSMUST00000103186.11	Cltc Ensembl NCBI MGI UniProt Show fit	clathrin, heavy polypeptide (Hc)
chr7_-_81104423 Show fit	3.63	ENSMUST00000178892.3 ENSMUST00000098331.10	Cpeb1 Ensembl NCBI MGI UniProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr1_-_52271455 Show fit	3.62	ENSMUST00000114512.8	Gls Ensembl NCBI MGI UniProt Show fit	glutaminase
chr2_+_29855572 Show fit	3.58	ENSMUST00000113719.9 ENSMUST00000113717.8 ENSMUST00000113741.8 ENSMUST00000100225.9 ENSMUST00000095083.11 ENSMUST00000046257.14	Sptan1 Ensembl NCBI MGI UniProt Show fit	spectrin alpha, non-erythrocytic 1
chr1_+_75526225 Show fit	3.58	ENSMUST00000154101.8	Slc4a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 4 (anion exchanger), member 3
chr15_-_100393369 Show fit	3.53	ENSMUST00000061457.7	Csrnp2 Ensembl NCBI MGI UniProt Show fit	cysteine-serine-rich nuclear protein 2
chr3_+_84859453 Show fit	3.49	ENSMUST00000029727.8	Fbxw7 Ensembl NCBI MGI UniProt Show fit	F-box and WD-40 domain protein 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.4	22.1	GO:0060466	activation of meiosis involved in egg activation(GO:0060466)
6.8	20.4	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
5.7	34.2	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
5.6	16.9	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
5.6	16.9	GO:2000295	regulation of hydrogen peroxide catabolic process(GO:2000295)
4.9	19.6	GO:0021586	pons maturation(GO:0021586)
4.2	37.8	GO:0005513	detection of calcium ion(GO:0005513)
3.0	12.0	GO:2001025	positive regulation of response to drug(GO:2001025)
2.9	23.5	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.4	7.1	GO:0030070	insulin processing(GO:0030070)
2.3	11.6	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
2.2	6.6	GO:0061107	seminal vesicle development(GO:0061107)
2.1	10.6	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
2.0	8.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
1.9	17.5	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.9	5.7	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.8	14.3	GO:0072321	chaperone-mediated protein transport(GO:0072321)
1.8	21.4	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.7	17.4	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
1.7	5.0	GO:0001982	baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
1.7	3.3	GO:0072054	renal outer medulla development(GO:0072054)
1.6	4.8	GO:0033577	protein glycosylation in endoplasmic reticulum(GO:0033577)
1.5	32.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4	10.0	GO:0048840	otolith development(GO:0048840)
1.4	5.6	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
1.4	8.4	GO:0035585	calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.4	8.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.3	16.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
1.3	13.2	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
1.3	6.6	GO:0030382	sperm mitochondrion organization(GO:0030382)
1.3	10.5	GO:0032796	uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
1.3	3.9	GO:0072708	response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
1.3	8.9	GO:0071321	cellular response to cGMP(GO:0071321)
1.3	29.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.3	6.3	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.2	6.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
1.2	7.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
1.2	3.6	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.2	7.3	GO:0006543	glutamine catabolic process(GO:0006543)
1.2	15.6	GO:2001135	regulation of endocytic recycling(GO:2001135)
1.2	4.7	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.2	5.8	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
1.1	3.4	GO:0071874	smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
1.1	4.4	GO:1903061	positive regulation of protein lipidation(GO:1903061) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.1	16.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
1.1	13.8	GO:0016188	synaptic vesicle maturation(GO:0016188)
1.1	5.3	GO:0032901	positive regulation of neurotrophin production(GO:0032901)
1.0	9.1	GO:1905245	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.0	6.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.0	4.9	GO:0010360	negative regulation of anion channel activity(GO:0010360)
1.0	15.4	GO:0043084	penile erection(GO:0043084)
1.0	6.7	GO:1901909	diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.0	4.8	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.9	9.2	GO:0014719	skeletal muscle satellite cell activation(GO:0014719)
0.9	2.8	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
0.9	2.7	GO:0006597	spermine biosynthetic process(GO:0006597)
0.9	7.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.9	2.6	GO:0006713	glucocorticoid catabolic process(GO:0006713)
0.8	12.5	GO:2000465	regulation of glycogen (starch) synthase activity(GO:2000465)
0.8	12.4	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.8	3.3	GO:1905077	negative regulation of interleukin-17 secretion(GO:1905077)
0.8	5.6	GO:0007256	activation of JNKK activity(GO:0007256)
0.8	2.4	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.8	12.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8	6.0	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.7	9.0	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.7	19.6	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.7	3.6	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.7	3.6	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.7	4.9	GO:0002447	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.7	9.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.7	3.5	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.7	3.4	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.6	9.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.6	4.3	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.6	3.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.6	7.3	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.6	10.8	GO:0042428	serotonin metabolic process(GO:0042428)
0.6	5.9	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.6	6.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.6	2.8	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5	13.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5	2.7	GO:0001550	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.5	2.1	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.5	1.6	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5	4.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.5	7.2	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.5	6.8	GO:0021873	forebrain neuroblast division(GO:0021873)
0.5	9.4	GO:0060081	membrane hyperpolarization(GO:0060081)
0.5	3.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.5	6.4	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.4	1.8	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4	2.2	GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.4	1.7	GO:0046381	CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.4	22.2	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.4	4.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.4	7.6	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.4	1.2	GO:0090367	negative regulation of mRNA modification(GO:0090367)
0.4	3.2	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.4	12.9	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.4	1.6	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.4	3.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.4	3.1	GO:0060313	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4	1.2	GO:0048003	synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4	5.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.4	2.7	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.4	5.4	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4	1.1	GO:0021664	rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.4	5.8	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.4	3.2	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.3	2.4	GO:0015871	choline transport(GO:0015871)
0.3	8.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.3	2.3	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3	23.1	GO:0007628	adult walking behavior(GO:0007628)
0.3	1.0	GO:0060618	nipple development(GO:0060618) mammary gland bud morphogenesis(GO:0060648)
0.3	5.8	GO:0033574	positive regulation of neurotransmitter secretion(GO:0001956) response to testosterone(GO:0033574)
0.3	7.3	GO:0021860	pyramidal neuron development(GO:0021860)
0.3	6.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.3	2.5	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.3	3.7	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.3	0.9	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3	1.5	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3	5.1	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
0.3	0.3	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3	1.5	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.3	2.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.3	9.6	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.3	3.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.3	1.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.3	1.1	GO:0031133	regulation of axon diameter(GO:0031133)
0.3	1.6	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.3	9.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.3	6.9	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.2	2.9	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2	4.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.2	1.6	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.2	6.0	GO:0060074	synapse maturation(GO:0060074)
0.2	4.4	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2	0.7	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2	1.7	GO:0001573	ganglioside metabolic process(GO:0001573)
0.2	2.1	GO:0032536	regulation of microvillus length(GO:0032532) regulation of cell projection size(GO:0032536)
0.2	1.9	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.2	6.5	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2	2.3	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.2	0.6	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.2	4.0	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2	14.8	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.2	3.0	GO:0032486	Rap protein signal transduction(GO:0032486)
0.2	1.3	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2	1.3	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2	6.4	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.2	10.9	GO:0051693	actin filament capping(GO:0051693)
0.2	0.9	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.2	1.4	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2	1.6	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.2	4.6	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2	6.2	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2	1.6	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.2	3.7	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.2	2.7	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.1	2.1	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.1	6.1	GO:0006270	DNA replication initiation(GO:0006270)
0.1	1.4	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1	1.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	3.9	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.1	4.8	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1	3.9	GO:0018345	protein palmitoylation(GO:0018345)
0.1	2.0	GO:0030834	regulation of actin filament depolymerization(GO:0030834)
0.1	1.6	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	8.6	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.1	1.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.6	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	2.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	3.9	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.1	1.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	9.8	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.1	5.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.8	GO:0034651	cortisol biosynthetic process(GO:0034651)
0.1	3.3	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.1	3.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.1	0.5	GO:0070829	heterochromatin maintenance(GO:0070829)
0.1	14.5	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.1	2.6	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1	2.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	3.2	GO:0007616	long-term memory(GO:0007616)
0.1	1.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	8.5	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.1	4.6	GO:0046677	response to antibiotic(GO:0046677)
0.1	7.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	6.0	GO:0034605	cellular response to heat(GO:0034605)
0.1	4.1	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.1	0.5	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.1	0.2	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	0.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.1	1.1	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	0.5	GO:0009405	pathogenesis(GO:0009405)
0.1	0.5	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	2.5	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.1	0.7	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	3.9	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	0.8	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.1	2.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1	1.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.1	0.3	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.1	1.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	2.5	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	1.5	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	1.0	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1	2.7	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	2.1	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.1	1.4	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	1.3	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	5.7	GO:0006165	nucleoside diphosphate phosphorylation(GO:0006165)
0.0	0.7	GO:1904869	protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.8	GO:0034063	stress granule assembly(GO:0034063)
0.0	3.4	GO:0045921	positive regulation of exocytosis(GO:0045921)
0.0	0.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.9	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.8	GO:0044804	nucleophagy(GO:0044804)
0.0	0.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	1.8	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0	1.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	1.8	GO:0031623	receptor internalization(GO:0031623)
0.0	0.3	GO:0043247	telomere maintenance in response to DNA damage(GO:0043247)
0.0	2.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.8	GO:0007032	endosome organization(GO:0007032)
0.0	0.7	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	1.4	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.4	GO:0006379	mRNA cleavage(GO:0006379)
0.0	1.4	GO:0000086	G2/M transition of mitotic cell cycle(GO:0000086)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.6	GO:0070527	platelet aggregation(GO:0070527)
0.0	1.1	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	2.3	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.0	0.2	GO:0000338	protein deneddylation(GO:0000338)
0.0	1.7	GO:0006338	chromatin remodeling(GO:0006338)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	16.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
3.4	20.4	GO:0044305	calyx of Held(GO:0044305)
3.0	8.9	GO:0098855	HCN channel complex(GO:0098855)
2.6	13.2	GO:0044316	cone cell pedicle(GO:0044316)
2.4	9.7	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.3	18.4	GO:0008091	spectrin(GO:0008091)
2.2	35.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
2.0	13.9	GO:0005955	calcineurin complex(GO:0005955)
2.0	9.8	GO:0044307	dendritic branch(GO:0044307)
1.5	41.7	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.5	7.6	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.4	20.4	GO:0044327	dendritic spine head(GO:0044327)
1.3	4.0	GO:1903095	microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
1.3	7.9	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
1.2	8.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
1.2	29.4	GO:0098839	postsynaptic density membrane(GO:0098839)
1.1	19.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.0	12.7	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.9	28.0	GO:0071565	nBAF complex(GO:0071565)
0.9	3.6	GO:0032437	cuticular plate(GO:0032437)
0.9	39.7	GO:0043194	axon initial segment(GO:0043194)
0.9	3.5	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.8	4.8	GO:0070449	elongin complex(GO:0070449)
0.7	7.7	GO:1990635	proximal dendrite(GO:1990635)
0.7	13.8	GO:0033270	paranode region of axon(GO:0033270)
0.7	22.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.6	3.6	GO:0031523	Myb complex(GO:0031523)
0.6	11.4	GO:0032279	asymmetric synapse(GO:0032279)
0.6	20.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.6	29.2	GO:0048786	presynaptic active zone(GO:0048786)
0.5	4.4	GO:0072687	meiotic spindle(GO:0072687)
0.5	20.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.5	25.1	GO:0051233	spindle midzone(GO:0051233)
0.5	3.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.5	3.5	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5	6.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.5	0.9	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.5	12.6	GO:0032590	dendrite membrane(GO:0032590)
0.4	1.7	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.4	7.7	GO:0032433	filopodium tip(GO:0032433)
0.4	6.3	GO:0031209	SCAR complex(GO:0031209)
0.4	2.8	GO:0097513	myosin II filament(GO:0097513)
0.4	1.2	GO:0098830	presynaptic endosome(GO:0098830)
0.4	6.2	GO:0001939	female pronucleus(GO:0001939)
0.4	22.5	GO:0060170	ciliary membrane(GO:0060170)
0.4	9.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.4	11.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.3	8.0	GO:0032426	stereocilium tip(GO:0032426)
0.3	2.6	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.3	6.9	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3	3.6	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3	25.8	GO:0043198	dendritic shaft(GO:0043198)
0.3	2.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	4.4	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.3	3.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	4.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.2	1.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	6.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	1.8	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.2	20.5	GO:0030667	secretory granule membrane(GO:0030667)
0.2	1.5	GO:0036449	microtubule minus-end(GO:0036449)
0.2	19.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.2	8.9	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2	0.9	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.2	20.8	GO:0030175	filopodium(GO:0030175)
0.2	1.5	GO:0001651	dense fibrillar component(GO:0001651)
0.2	23.4	GO:0043204	perikaryon(GO:0043204)
0.2	1.8	GO:0097542	ciliary tip(GO:0097542)
0.2	1.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	2.6	GO:0030125	clathrin vesicle coat(GO:0030125)
0.1	2.4	GO:0031143	pseudopodium(GO:0031143)
0.1	2.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	0.5	GO:0032021	NELF complex(GO:0032021)
0.1	2.9	GO:0042734	presynaptic membrane(GO:0042734)
0.1	4.7	GO:0031201	SNARE complex(GO:0031201)
0.1	0.2	GO:0002944	cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1	15.2	GO:0043197	dendritic spine(GO:0043197)
0.1	3.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	0.3	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.1	15.9	GO:0030027	lamellipodium(GO:0030027)
0.1	20.5	GO:0031225	anchored component of membrane(GO:0031225)
0.1	17.2	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	41.1	GO:0016607	nuclear speck(GO:0016607)
0.1	1.1	GO:0034464	BBSome(GO:0034464)
0.1	0.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	8.0	GO:0016234	inclusion body(GO:0016234)
0.1	44.0	GO:0043025	neuronal cell body(GO:0043025)
0.1	1.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.8	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	2.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	1.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	4.9	GO:0030426	growth cone(GO:0030426)
0.1	0.7	GO:0017119	Golgi transport complex(GO:0017119)
0.1	1.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.1	0.7	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	1.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	1.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	1.0	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:0070722	Tle3-Aes complex(GO:0070722)
0.0	3.9	GO:0055037	recycling endosome(GO:0055037)
0.0	0.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0043293	apoptosome(GO:0043293)
0.0	0.7	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.7	GO:0031011	Ino80 complex(GO:0031011)
0.0	0.8	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.9	GO:0005776	autophagosome(GO:0005776)
0.0	1.3	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.6	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.6	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	2.1	GO:0005884	actin filament(GO:0005884)
0.0	1.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	3.3	GO:0005769	early endosome(GO:0005769)
0.0	1.5	GO:0016459	myosin complex(GO:0016459)
0.0	0.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.8	GO:0030139	endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.6	19.9	GO:0030348	syntaxin-3 binding(GO:0030348)
3.4	13.6	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
2.9	14.3	GO:0097001	ceramide binding(GO:0097001)
2.6	13.2	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
2.3	13.9	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
2.3	34.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
2.0	13.8	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.8	5.3	GO:0047291	lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.6	4.8	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
1.5	16.9	GO:1903136	cuprous ion binding(GO:1903136)
1.5	7.5	GO:2001069	glycogen binding(GO:2001069)
1.5	8.9	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
1.5	7.4	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
1.4	8.6	GO:0004614	phosphoglucomutase activity(GO:0004614)
1.4	10.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
1.4	28.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
1.3	7.7	GO:0004994	somatostatin receptor activity(GO:0004994)
1.3	6.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.2	6.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
1.2	9.8	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.2	7.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
1.2	7.3	GO:0004359	glutaminase activity(GO:0004359)
1.2	5.8	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1	7.7	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
1.1	38.0	GO:0032183	SUMO binding(GO:0032183)
1.1	4.3	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.0	30.8	GO:0017075	syntaxin-1 binding(GO:0017075)
1.0	6.9	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
1.0	6.7	GO:0034432	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.0	28.6	GO:0031402	sodium ion binding(GO:0031402)
0.9	24.0	GO:0043274	phospholipase binding(GO:0043274)
0.9	4.3	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.9	2.6	GO:0097100	supercoiled DNA binding(GO:0097100)
0.8	3.4	GO:0031762	alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.8	3.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.8	4.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.8	4.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.8	2.4	GO:0035939	microsatellite binding(GO:0035939)
0.8	21.4	GO:0003680	AT DNA binding(GO:0003680)
0.8	7.8	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.8	2.3	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.7	9.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.6	1.9	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.6	23.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.6	5.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.6	18.0	GO:0070300	phosphatidic acid binding(GO:0070300)
0.6	3.7	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.6	11.0	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.6	3.5	GO:0050816	phosphothreonine binding(GO:0050816)
0.6	9.7	GO:0005522	profilin binding(GO:0005522)
0.6	6.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5	19.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	3.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.5	2.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.5	2.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.5	5.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.5	10.5	GO:0032036	myosin heavy chain binding(GO:0032036)
0.5	1.9	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5	5.9	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.4	21.6	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.4	2.7	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.4	3.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.4	3.4	GO:0051425	PTB domain binding(GO:0051425)
0.4	2.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.4	2.5	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4	5.7	GO:0004017	adenylate kinase activity(GO:0004017)
0.4	28.8	GO:0001540	beta-amyloid binding(GO:0001540)
0.4	7.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.4	11.6	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4	7.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	22.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.3	10.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.3	1.6	GO:0045504	dynein heavy chain binding(GO:0045504)
0.3	14.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.3	24.6	GO:0030507	spectrin binding(GO:0030507)
0.3	3.6	GO:0032051	clathrin light chain binding(GO:0032051)
0.3	6.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.3	6.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.3	26.8	GO:0035254	glutamate receptor binding(GO:0035254)
0.3	22.6	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.3	3.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3	4.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	1.7	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	11.0	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	2.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	1.8	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.2	1.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.2	2.7	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.2	1.5	GO:0044547	rRNA primary transcript binding(GO:0042134) DNA topoisomerase binding(GO:0044547)
0.2	2.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	2.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.2	0.6	GO:0001132	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.2	0.6	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2	5.4	GO:0030552	cAMP binding(GO:0030552)
0.2	1.7	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.2	3.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2	18.1	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.2	8.6	GO:0030332	cyclin binding(GO:0030332)
0.2	2.6	GO:1990226	histone methyltransferase binding(GO:1990226)
0.2	2.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	3.1	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.2	1.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	3.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.2	1.4	GO:0042285	xylosyltransferase activity(GO:0042285)
0.2	8.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.2	2.8	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	4.4	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.1	3.4	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	4.8	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	1.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	7.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	3.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	2.0	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	4.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	3.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	1.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	6.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	6.0	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.8	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	2.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	1.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.3	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.1	1.9	GO:0050811	GABA receptor binding(GO:0050811)
0.1	4.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0004849	uridine kinase activity(GO:0004849)
0.1	1.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	6.6	GO:0004620	phospholipase activity(GO:0004620)
0.1	1.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	1.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	1.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	2.3	GO:0017022	myosin binding(GO:0017022)
0.1	1.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	1.5	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.1	12.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	7.8	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	6.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	6.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	1.0	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	3.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.9	GO:0031489	myosin V binding(GO:0031489)
0.0	1.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	4.0	GO:0051087	chaperone binding(GO:0051087)
0.0	2.8	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	1.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	11.5	GO:0005096	GTPase activator activity(GO:0005096)
0.0	1.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	1.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0097157	pre-mRNA intronic binding(GO:0097157) mRNA CDS binding(GO:1990715)
0.0	1.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	6.0	GO:0000287	magnesium ion binding(GO:0000287)
0.0	2.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.0	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	1.1	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.7	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.7	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	3.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	4.8	GO:0003924	GTPase activity(GO:0003924)
0.0	2.4	GO:0005178	integrin binding(GO:0005178)
0.0	1.3	GO:0070888	E-box binding(GO:0070888)
0.0	9.1	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.4	GO:0015026	coreceptor activity(GO:0015026)
0.0	1.3	GO:0005525	GTP binding(GO:0005525)
0.0	0.8	GO:0008173	RNA methyltransferase activity(GO:0008173)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	39.4	PID RAS PATHWAY	Regulation of Ras family activation
0.6	20.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.6	34.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.6	19.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.6	11.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	23.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.5	22.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.4	2.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4	20.8	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	14.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.3	7.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	3.4	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.3	10.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	9.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	4.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	9.1	PID AURORA A PATHWAY	Aurora A signaling
0.2	32.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	2.3	PID MYC PATHWAY	C-MYC pathway
0.2	5.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	5.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	1.7	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.2	3.3	PID ARF 3PATHWAY	Arf1 pathway
0.2	3.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	8.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	14.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	2.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	4.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	4.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	1.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	3.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	3.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	3.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	0.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.2	PID ATM PATHWAY	ATM pathway
0.0	2.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	3.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	44.6	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
1.5	45.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
1.1	18.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.1	56.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.1	31.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.8	13.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.8	12.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7	40.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.7	8.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6	7.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.5	19.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.5	13.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.5	11.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.4	8.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	25.5	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.4	13.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.4	16.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.4	12.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.4	8.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.4	2.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4	6.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.4	11.6	REACTOME KINESINS	Genes involved in Kinesins
0.4	7.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	3.7	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.3	26.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	3.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	1.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	3.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2	4.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	4.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.2	5.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	2.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	2.7	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	4.0	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	3.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	3.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	4.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	4.8	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	2.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	3.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	0.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	2.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	5.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	1.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	2.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	2.6	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.1	5.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	12.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	1.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	8.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Results for Egr1

Z-value: 1.94

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Transcription factors associated with Egr1

Activity-expression correlation:

Activity profile of Egr1 motif

Sorted Z-values of Egr1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: