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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Egr3

Z-value: 0.81

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Transcription factors associated with Egr3

Gene Symbol Gene ID Gene Info
Egr3
ENSMUSG00000033730.5 Egr3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Egr3mm39_v1_chr14_+_70314652_703146710.522.8e-06Click!

Activity profile of Egr3 motif

Sorted Z-values of Egr3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_55747902 9.76 ENSMUST00000165262.8
ENSMUST00000074225.11
Cpne6
copine VI
chr10_+_40759468 6.77 ENSMUST00000019975.14
Wasf1
WASP family, member 1
chr10_+_40759815 6.62 ENSMUST00000105509.2
Wasf1
WASP family, member 1
chr11_-_99313078 5.23 ENSMUST00000017741.4
Krt12
keratin 12
chr6_+_103488044 5.19 ENSMUST00000203830.3
Chl1
cell adhesion molecule L1-like
chr6_+_103487973 5.09 ENSMUST00000066905.9
Chl1
cell adhesion molecule L1-like
chr1_+_125604706 4.76 ENSMUST00000027581.7
Gpr39
G protein-coupled receptor 39
chr18_+_59195534 4.59 ENSMUST00000058633.9
ENSMUST00000175897.8
ENSMUST00000118510.8
ENSMUST00000175830.2
Minar2
membrane integral NOTCH2 associated receptor 2
chr10_+_106306122 4.58 ENSMUST00000029404.17
ENSMUST00000217854.2
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_+_66205932 4.51 ENSMUST00000022616.14
Clu
clusterin
chr19_-_38113249 4.50 ENSMUST00000112335.4
Rbp4
retinol binding protein 4, plasma
chr1_+_133291302 4.48 ENSMUST00000135222.9
Etnk2
ethanolamine kinase 2
chr4_+_123077286 4.45 ENSMUST00000126995.2
Hpcal4
hippocalcin-like 4
chrX_+_142447361 4.34 ENSMUST00000126592.8
ENSMUST00000156449.8
ENSMUST00000155215.8
ENSMUST00000112865.8
Pak3
p21 (RAC1) activated kinase 3
chr3_-_126955976 4.30 ENSMUST00000182994.8
Ank2
ankyrin 2, brain
chr1_+_158190090 4.17 ENSMUST00000194369.6
ENSMUST00000195311.6
Astn1
astrotactin 1
chr12_+_49429790 4.15 ENSMUST00000021333.5
Foxg1
forkhead box G1
chr9_+_26645024 3.89 ENSMUST00000160899.8
ENSMUST00000161431.3
ENSMUST00000159799.8
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr16_+_94171477 3.79 ENSMUST00000117648.9
ENSMUST00000147352.8
ENSMUST00000150346.8
ENSMUST00000155692.8
ENSMUST00000153988.9
ENSMUST00000139513.9
ENSMUST00000141856.8
ENSMUST00000152117.8
ENSMUST00000150097.8
ENSMUST00000122895.8
ENSMUST00000151770.8
ENSMUST00000231569.2
ENSMUST00000147046.8
ENSMUST00000149885.8
ENSMUST00000127667.8
ENSMUST00000119131.3
ENSMUST00000145883.2
Ttc3
tetratricopeptide repeat domain 3
chr12_+_49429574 3.74 ENSMUST00000179669.3
Foxg1
forkhead box G1
chr11_+_4833186 3.63 ENSMUST00000139737.2
Nipsnap1
nipsnap homolog 1
chrX_+_142447286 3.51 ENSMUST00000112868.8
Pak3
p21 (RAC1) activated kinase 3
chr11_+_71641505 3.31 ENSMUST00000021168.14
Wscd1
WSC domain containing 1
chr19_-_38113056 3.31 ENSMUST00000236283.2
Rbp4
retinol binding protein 4, plasma
chr1_+_120268299 3.28 ENSMUST00000037286.12
C1ql2
complement component 1, q subcomponent-like 2
chr17_-_29457064 3.26 ENSMUST00000024805.15
Cpne5
copine V
chr6_+_71684846 3.19 ENSMUST00000212792.2
Reep1
receptor accessory protein 1
chr16_-_88087087 3.13 ENSMUST00000211444.2
ENSMUST00000023652.16
ENSMUST00000072256.13
Grik1
glutamate receptor, ionotropic, kainate 1
chr8_+_63404395 3.13 ENSMUST00000119068.8
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chrX_+_35459621 3.12 ENSMUST00000115256.2
Zcchc12
zinc finger, CCHC domain containing 12
chr15_+_99122742 2.78 ENSMUST00000041415.5
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_-_109613040 2.75 ENSMUST00000020938.8
Fam20a
FAM20A, golgi associated secretory pathway pseudokinase
chr7_+_80510658 2.60 ENSMUST00000132163.8
ENSMUST00000205361.2
ENSMUST00000147125.2
Zscan2
zinc finger and SCAN domain containing 2
chr12_-_84497718 2.56 ENSMUST00000085192.7
ENSMUST00000220491.2
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr8_+_63404228 2.52 ENSMUST00000118003.8
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr10_-_68114543 2.49 ENSMUST00000219238.2
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr11_+_71641806 2.46 ENSMUST00000108511.8
Wscd1
WSC domain containing 1
chr12_+_58258558 2.23 ENSMUST00000110671.3
ENSMUST00000044299.3
Sstr1
somatostatin receptor 1
chr11_-_107805830 2.19 ENSMUST00000039071.3
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr17_+_25798059 2.15 ENSMUST00000141606.3
ENSMUST00000063344.15
ENSMUST00000116641.9
Lmf1
lipase maturation factor 1
chr6_+_103488291 2.11 ENSMUST00000204321.2
Chl1
cell adhesion molecule L1-like
chr10_+_80134917 2.08 ENSMUST00000154212.8
Apc2
APC regulator of WNT signaling pathway 2
chr15_-_78428865 1.95 ENSMUST00000053239.4
Sstr3
somatostatin receptor 3
chr7_-_142223662 1.92 ENSMUST00000228850.2
Gm49394
predicted gene, 49394
chr1_-_74639723 1.90 ENSMUST00000127938.8
ENSMUST00000154874.8
Rnf25
ring finger protein 25
chr10_+_83558729 1.90 ENSMUST00000150459.3
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr2_-_121244251 1.90 ENSMUST00000038073.5
Catsper2
cation channel, sperm associated 2
chr1_-_160134873 1.85 ENSMUST00000193185.6
Rabgap1l
RAB GTPase activating protein 1-like
chr3_+_105359641 1.84 ENSMUST00000098761.10
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr11_-_98666159 1.80 ENSMUST00000064941.7
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr15_-_77037972 1.76 ENSMUST00000111581.4
ENSMUST00000166610.8
Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_94063823 1.71 ENSMUST00000044602.8
Ces1g
carboxylesterase 1G
chr15_+_81119700 1.70 ENSMUST00000166855.3
Mchr1
melanin-concentrating hormone receptor 1
chr9_-_50639367 1.69 ENSMUST00000117646.8
Dixdc1
DIX domain containing 1
chr1_-_9369463 1.68 ENSMUST00000140295.8
Sntg1
syntrophin, gamma 1
chr8_+_119010458 1.67 ENSMUST00000117160.2
Cdh13
cadherin 13
chr6_-_88851579 1.62 ENSMUST00000061262.11
ENSMUST00000140455.8
ENSMUST00000145780.2
Podxl2
podocalyxin-like 2
chr7_+_18810167 1.62 ENSMUST00000108479.2
Dmwd
dystrophia myotonica-containing WD repeat motif
chr2_-_58457168 1.51 ENSMUST00000056376.12
Acvr1
activin A receptor, type 1
chr10_+_3784877 1.51 ENSMUST00000239159.2
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr7_+_44358144 1.50 ENSMUST00000085422.4
Izumo2
IZUMO family member 2
chr5_+_138278777 1.48 ENSMUST00000048028.15
ENSMUST00000162245.8
ENSMUST00000161691.2
Stag3
stromal antigen 3
chr10_+_29020055 1.41 ENSMUST00000216757.2
Soga3
SOGA family member 3
chr7_+_43361930 1.34 ENSMUST00000066834.8
Klk13
kallikrein related-peptidase 13
chr1_+_164135230 1.27 ENSMUST00000193683.6
Nme7
NME/NM23 family member 7
chr7_+_48608800 1.26 ENSMUST00000183659.8
Nav2
neuron navigator 2
chr9_-_58111589 1.23 ENSMUST00000217578.2
ENSMUST00000114144.9
ENSMUST00000214649.2
Islr
Islr2
immunoglobulin superfamily containing leucine-rich repeat
immunoglobulin superfamily containing leucine-rich repeat 2
chr12_+_108601963 1.22 ENSMUST00000223109.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr3_+_93301003 1.17 ENSMUST00000045912.3
Rptn
repetin
chr12_+_108602008 1.17 ENSMUST00000172409.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr1_-_164135008 1.09 ENSMUST00000027866.11
ENSMUST00000120447.8
ENSMUST00000086032.4
Blzf1
basic leucine zipper nuclear factor 1
chr13_+_59733163 1.05 ENSMUST00000166923.9
Naa35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr7_+_18810097 1.05 ENSMUST00000032570.14
Dmwd
dystrophia myotonica-containing WD repeat motif
chr10_+_69370038 1.03 ENSMUST00000182439.8
ENSMUST00000092434.12
ENSMUST00000047061.13
ENSMUST00000092432.12
ENSMUST00000092431.12
ENSMUST00000054167.15
Ank3
ankyrin 3, epithelial
chr19_+_16933471 1.02 ENSMUST00000087689.5
Prune2
prune homolog 2
chr19_+_59447950 0.96 ENSMUST00000174353.2
Emx2
empty spiracles homeobox 2
chr16_-_88860890 0.92 ENSMUST00000089104.3
1110025L11Rik
RIKEN cDNA 1110025L11 gene
chr4_-_20778530 0.86 ENSMUST00000119374.8
Nkain3
Na+/K+ transporting ATPase interacting 3
chr5_-_21850579 0.85 ENSMUST00000051358.11
Fbxl13
F-box and leucine-rich repeat protein 13
chr7_+_3648264 0.83 ENSMUST00000206287.2
ENSMUST00000038913.16
Cnot3
CCR4-NOT transcription complex, subunit 3
chr4_-_129556234 0.82 ENSMUST00000003828.11
Kpna6
karyopherin (importin) alpha 6
chr10_-_127504416 0.78 ENSMUST00000129252.2
Nab2
Ngfi-A binding protein 2
chr2_+_3115250 0.73 ENSMUST00000072955.12
Fam171a1
family with sequence similarity 171, member A1
chr5_+_138278502 0.71 ENSMUST00000160729.8
Stag3
stromal antigen 3
chr9_+_21077010 0.70 ENSMUST00000039413.15
Pde4a
phosphodiesterase 4A, cAMP specific
chr16_+_17716480 0.70 ENSMUST00000055374.8
Tssk2
testis-specific serine kinase 2
chr7_-_103799746 0.67 ENSMUST00000059121.5
Ubqlnl
ubiquilin-like
chr4_-_129132963 0.62 ENSMUST00000097873.10
C77080
expressed sequence C77080
chr9_+_119723931 0.57 ENSMUST00000036561.8
ENSMUST00000217472.2
ENSMUST00000215307.2
Wdr48
WD repeat domain 48
chr12_+_86999366 0.55 ENSMUST00000191463.2
Cipc
CLOCK interacting protein, circadian
chr5_+_129792548 0.53 ENSMUST00000119576.8
ENSMUST00000042191.12
ENSMUST00000118420.8
ENSMUST00000154358.6
ENSMUST00000121339.2
ENSMUST00000119604.8
ENSMUST00000136108.8
ENSMUST00000121813.8
ENSMUST00000119985.2
ENSMUST00000138812.2
Mrps17
mitochondrial ribosomal protein S17
chrX_+_159945740 0.51 ENSMUST00000074802.12
ENSMUST00000019101.11
ENSMUST00000112345.8
Scml2
Scm polycomb group protein like 2
chr16_+_21023505 0.50 ENSMUST00000006112.7
Ephb3
Eph receptor B3
chr3_-_89867869 0.49 ENSMUST00000069805.14
Atp8b2
ATPase, class I, type 8B, member 2
chr6_-_83549399 0.42 ENSMUST00000206592.2
ENSMUST00000206400.2
Stambp
STAM binding protein
chr7_-_118783820 0.42 ENSMUST00000084650.6
Gpr139
G protein-coupled receptor 139
chr19_-_4665668 0.39 ENSMUST00000113822.3
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr4_+_99812912 0.33 ENSMUST00000102783.5
Pgm1
phosphoglucomutase 1
chr17_-_46638874 0.33 ENSMUST00000047970.14
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr5_-_138278223 0.28 ENSMUST00000014089.9
ENSMUST00000161827.8
Gpc2
glypican 2 (cerebroglycan)
chr5_+_143864993 0.26 ENSMUST00000172367.3
Gm42421
predicted gene, 42421
chr17_-_46638915 0.25 ENSMUST00000167360.8
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr19_-_6127211 0.24 ENSMUST00000160590.2
ENSMUST00000025711.13
Vps51
VPS51 GARP complex subunit
chrX_+_159945990 0.24 ENSMUST00000077375.5
Scml2
Scm polycomb group protein like 2
chr4_-_40948196 0.23 ENSMUST00000030125.5
ENSMUST00000108089.8
ENSMUST00000191273.7
Bag1
BCL2-associated athanogene 1
chr10_+_69369854 0.23 ENSMUST00000182557.8
Ank3
ankyrin 3, epithelial
chr6_-_49191891 0.22 ENSMUST00000031838.9
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr4_+_57637817 0.20 ENSMUST00000150412.4
Pakap
paralemmin A kinase anchor protein
chr6_-_30873669 0.13 ENSMUST00000048774.13
ENSMUST00000166192.7
Copg2
coatomer protein complex, subunit gamma 2
chr19_-_4665509 0.12 ENSMUST00000053597.3
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr8_-_49008881 0.10 ENSMUST00000110345.8
Tenm3
teneurin transmembrane protein 3
chr2_-_111100733 0.10 ENSMUST00000099619.6
Olfr1277
olfactory receptor 1277
chr15_+_43340609 0.05 ENSMUST00000022962.8
Emc2
ER membrane protein complex subunit 2
chr18_+_65831324 0.05 ENSMUST00000115097.8
ENSMUST00000117694.2
ENSMUST00000235962.2
Oacyl
O-acyltransferase like
chr4_+_40948407 0.01 ENSMUST00000030128.6
Chmp5
charged multivesicular body protein 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0021852 pyramidal neuron migration(GO:0021852)
1.6 7.8 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.3 13.4 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.8 4.5 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 4.8 GO:0060455 gastric emptying(GO:0035483) negative regulation of gastric acid secretion(GO:0060455)
0.6 2.6 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.6 1.7 GO:0034378 chylomicron assembly(GO:0034378) regulation of chylomicron remnant clearance(GO:0090320)
0.5 4.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 5.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 2.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 4.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 2.2 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.4 3.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.4 2.2 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 1.8 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 5.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 1.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 2.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.3 1.5 GO:2000017 endocardial cushion fusion(GO:0003274) positive regulation of determination of dorsal identity(GO:2000017)
0.3 13.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 1.7 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 4.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 3.9 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.2 12.4 GO:0035640 exploration behavior(GO:0035640)
0.2 2.5 GO:0060613 fat pad development(GO:0060613)
0.2 7.9 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.2 1.3 GO:0021564 vagus nerve development(GO:0021564)
0.2 2.7 GO:0070166 enamel mineralization(GO:0070166)
0.2 2.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.8 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.2 1.8 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.2 1.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 3.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.6 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 1.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.3 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 2.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 2.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.9 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.0 GO:0021796 dentate gyrus development(GO:0021542) cerebral cortex regionalization(GO:0021796)
0.0 1.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.7 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 3.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.5 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 3.6 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 2.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.4 GO:0031209 SCAR complex(GO:0031209)
0.5 1.5 GO:0048179 activin receptor complex(GO:0048179)
0.4 2.2 GO:0000802 transverse filament(GO:0000802)
0.4 3.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 4.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 0.9 GO:0031417 NatC complex(GO:0031417)
0.2 9.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.9 GO:0036128 CatSper complex(GO:0036128)
0.1 2.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 5.6 GO:0043034 costamere(GO:0043034)
0.1 3.6 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.2 GO:0005882 intermediate filament(GO:0005882)
0.0 12.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0034632 retinol transporter activity(GO:0034632)
1.1 4.5 GO:0004103 choline kinase activity(GO:0004103)
0.7 4.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 3.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 2.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 3.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 7.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 1.7 GO:0055100 adiponectin binding(GO:0055100)
0.3 5.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 4.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 13.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 8.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.1 GO:0032183 SUMO binding(GO:0032183)
0.1 5.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 5.6 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 11.3 GO:0002020 protease binding(GO:0002020)
0.1 1.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 2.0 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 1.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.6 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 2.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 21.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 6.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 6.4 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)