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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Egr4

Z-value: 0.62

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Transcription factors associated with Egr4

Gene Symbol Gene ID Gene Info
Egr4
ENSMUSG00000071341.5 Egr4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Egr4mm39_v1_chr6_-_85490568_85490573-0.142.3e-01Click!

Activity profile of Egr4 motif

Sorted Z-values of Egr4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_135060431 3.53 ENSMUST00000187985.7
ENSMUST00000049449.11
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr7_+_44485704 3.42 ENSMUST00000033015.8
Il4i1
interleukin 4 induced 1
chr14_+_79718604 2.52 ENSMUST00000040131.13
Elf1
E74-like factor 1
chr9_-_119812042 2.33 ENSMUST00000214058.2
Csrnp1
cysteine-serine-rich nuclear protein 1
chr18_+_35962832 2.20 ENSMUST00000060722.8
Cxxc5
CXXC finger 5
chr9_-_88613967 2.03 ENSMUST00000098486.4
Bcl2a1d
B cell leukemia/lymphoma 2 related protein A1d
chr12_+_76417040 2.02 ENSMUST00000042779.4
Zbtb1
zinc finger and BTB domain containing 1
chr7_-_37806912 1.97 ENSMUST00000108023.10
Ccne1
cyclin E1
chr11_+_94900677 1.96 ENSMUST00000055947.10
Samd14
sterile alpha motif domain containing 14
chr10_+_43455157 1.94 ENSMUST00000058714.10
Cd24a
CD24a antigen
chr9_-_44145280 1.87 ENSMUST00000205968.2
ENSMUST00000206147.2
ENSMUST00000037644.8
Cbl
Casitas B-lineage lymphoma
chr2_+_13579092 1.84 ENSMUST00000193675.2
Vim
vimentin
chr16_+_93680783 1.80 ENSMUST00000023666.11
ENSMUST00000117099.8
Chaf1b
chromatin assembly factor 1, subunit B (p60)
chr2_+_13578738 1.71 ENSMUST00000141365.3
ENSMUST00000028062.8
Vim
vimentin
chr17_-_27060539 1.68 ENSMUST00000015723.5
Nkx2-5
NK2 homeobox 5
chr16_+_93629009 1.61 ENSMUST00000044068.10
ENSMUST00000202261.5
ENSMUST00000201097.3
Morc3
microrchidia 3
chr9_-_44145309 1.52 ENSMUST00000206720.2
Cbl
Casitas B-lineage lymphoma
chr10_-_116309764 1.48 ENSMUST00000068233.11
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_-_9888804 1.44 ENSMUST00000114915.3
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chr18_+_46874920 1.38 ENSMUST00000025357.9
ENSMUST00000225520.2
Ap3s1
adaptor-related protein complex 3, sigma 1 subunit
chr17_+_26357648 1.34 ENSMUST00000074370.10
ENSMUST00000118904.9
ENSMUST00000163421.8
Axin1
axin 1
chr17_+_69690018 1.29 ENSMUST00000112674.8
Zbtb14
zinc finger and BTB domain containing 14
chr18_+_35962881 1.27 ENSMUST00000237291.2
Cxxc5
CXXC finger 5
chr19_-_5323092 1.25 ENSMUST00000237463.2
ENSMUST00000025786.9
Pacs1
phosphofurin acidic cluster sorting protein 1
chr14_+_76082736 1.24 ENSMUST00000142061.3
Tpt1
tumor protein, translationally-controlled 1
chr15_+_58004793 1.15 ENSMUST00000227142.2
ENSMUST00000226955.2
Wdyhv1
WDYHV motif containing 1
chr11_+_114742331 1.15 ENSMUST00000177952.8
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr10_+_19467697 1.13 ENSMUST00000020188.13
Ifngr1
interferon gamma receptor 1
chr7_-_66339319 1.12 ENSMUST00000124899.8
Asb7
ankyrin repeat and SOCS box-containing 7
chr10_+_67371295 1.10 ENSMUST00000145754.8
ENSMUST00000145936.2
Egr2
early growth response 2
chr2_+_117942357 1.07 ENSMUST00000039559.9
Thbs1
thrombospondin 1
chr11_+_114742619 1.05 ENSMUST00000053361.12
ENSMUST00000021071.14
ENSMUST00000136785.2
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr17_-_31877703 1.05 ENSMUST00000236475.2
ENSMUST00000166526.9
ENSMUST00000014684.6
U2af1
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
chr7_+_66339637 1.04 ENSMUST00000153007.2
ENSMUST00000121777.9
ENSMUST00000150071.8
ENSMUST00000077967.13
Lins1
lines homolog 1
chr19_-_8763609 1.04 ENSMUST00000177216.8
ENSMUST00000176610.9
ENSMUST00000177056.8
Taf6l
TATA-box binding protein associated factor 6 like
chr10_+_17931459 1.02 ENSMUST00000154718.8
ENSMUST00000126390.8
ENSMUST00000164556.8
ENSMUST00000150029.8
Reps1
RalBP1 associated Eps domain containing protein
chrX_+_7708295 1.02 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
Otud5
OTU domain containing 5
chr10_+_128067934 1.01 ENSMUST00000055539.11
ENSMUST00000105244.8
ENSMUST00000105243.9
Timeless
timeless circadian clock 1
chr18_+_46874970 1.00 ENSMUST00000224622.2
Ap3s1
adaptor-related protein complex 3, sigma 1 subunit
chr10_-_80413119 0.99 ENSMUST00000038558.9
Klf16
Kruppel-like factor 16
chr9_+_65816206 0.98 ENSMUST00000205379.2
ENSMUST00000206048.2
ENSMUST00000034949.10
ENSMUST00000154589.2
Csnk1g1
casein kinase 1, gamma 1
chr14_-_79718890 0.98 ENSMUST00000022601.7
Wbp4
WW domain binding protein 4
chr4_+_150171822 0.96 ENSMUST00000094451.4
Gpr157
G protein-coupled receptor 157
chr14_+_76082533 0.95 ENSMUST00000110894.9
Tpt1
tumor protein, translationally-controlled 1
chr19_+_25483070 0.94 ENSMUST00000087525.5
Dmrt1
doublesex and mab-3 related transcription factor 1
chr19_+_25482982 0.92 ENSMUST00000025755.11
Dmrt1
doublesex and mab-3 related transcription factor 1
chr9_+_21077010 0.92 ENSMUST00000039413.15
Pde4a
phosphodiesterase 4A, cAMP specific
chrX_-_74174608 0.91 ENSMUST00000033775.9
Mpp1
membrane protein, palmitoylated
chr6_+_70933434 0.91 ENSMUST00000163089.2
ENSMUST00000069634.6
Foxi3
forkhead box I3
chr13_+_55593116 0.82 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
Grk6
G protein-coupled receptor kinase 6
chr7_-_80020830 0.78 ENSMUST00000205436.2
ENSMUST00000098346.5
Man2a2
mannosidase 2, alpha 2
chr9_+_65816370 0.77 ENSMUST00000206594.2
Csnk1g1
casein kinase 1, gamma 1
chr7_-_126073994 0.76 ENSMUST00000205733.2
ENSMUST00000205889.2
Sh2b1
SH2B adaptor protein 1
chr3_+_145630017 0.75 ENSMUST00000029842.9
Bcl10
B cell leukemia/lymphoma 10
chr4_-_3938352 0.75 ENSMUST00000003369.10
Plag1
pleiomorphic adenoma gene 1
chr19_-_8763771 0.74 ENSMUST00000176496.8
Taf6l
TATA-box binding protein associated factor 6 like
chr4_+_99544536 0.71 ENSMUST00000087285.5
Foxd3
forkhead box D3
chr9_-_110571645 0.71 ENSMUST00000006005.12
Pth1r
parathyroid hormone 1 receptor
chr16_+_93680846 0.70 ENSMUST00000142316.2
Chaf1b
chromatin assembly factor 1, subunit B (p60)
chr9_+_108225026 0.69 ENSMUST00000035237.12
ENSMUST00000194959.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr11_+_45871135 0.69 ENSMUST00000049038.4
Sox30
SRY (sex determining region Y)-box 30
chr9_-_44144772 0.68 ENSMUST00000205755.2
Cbl
Casitas B-lineage lymphoma
chr11_+_114743044 0.63 ENSMUST00000142262.2
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr14_+_71127540 0.56 ENSMUST00000022699.10
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr1_-_97589365 0.53 ENSMUST00000153115.8
ENSMUST00000142234.2
Macir
macrophage immunometabolism regulator
chr1_-_36978602 0.49 ENSMUST00000027290.12
Tmem131
transmembrane protein 131
chr1_+_153300874 0.45 ENSMUST00000042373.12
Shcbp1l
Shc SH2-domain binding protein 1-like
chr9_-_44352312 0.44 ENSMUST00000215980.2
ENSMUST00000098837.3
Foxr1
forkhead box R1
chr16_+_35891991 0.44 ENSMUST00000164916.9
Ccdc58
coiled-coil domain containing 58
chr11_-_96668318 0.42 ENSMUST00000127375.2
ENSMUST00000021246.9
ENSMUST00000107661.10
Snx11
sorting nexin 11
chr11_+_4136789 0.41 ENSMUST00000041042.13
ENSMUST00000180088.2
Tbc1d10a
TBC1 domain family, member 10a
chr10_+_121575819 0.39 ENSMUST00000065600.8
ENSMUST00000136432.2
BC048403
cDNA sequence BC048403
chr17_+_83658354 0.35 ENSMUST00000096766.12
ENSMUST00000049503.10
ENSMUST00000112363.10
ENSMUST00000234460.2
Eml4
echinoderm microtubule associated protein like 4
chr6_-_85428207 0.35 ENSMUST00000113770.2
ENSMUST00000032080.9
Pradc1
protease-associated domain containing 1
chr6_-_91388345 0.35 ENSMUST00000032180.7
Wnt7a
wingless-type MMTV integration site family, member 7A
chr11_+_103007054 0.34 ENSMUST00000053063.7
Hexim1
hexamethylene bis-acetamide inducible 1
chrX_-_74174524 0.33 ENSMUST00000114091.8
Mpp1
membrane protein, palmitoylated
chr14_+_56905698 0.32 ENSMUST00000116468.2
Mphosph8
M-phase phosphoprotein 8
chr11_+_69891398 0.29 ENSMUST00000019362.15
ENSMUST00000190940.2
Dvl2
dishevelled segment polarity protein 2
chr13_-_111626562 0.28 ENSMUST00000091236.11
ENSMUST00000047627.14
Gpbp1
GC-rich promoter binding protein 1
chr2_-_155849839 0.27 ENSMUST00000086145.10
ENSMUST00000144686.8
ENSMUST00000140657.8
6430550D23Rik
RIKEN cDNA 6430550D23 gene
chr5_-_145020840 0.24 ENSMUST00000151196.2
Kpna7
karyopherin alpha 7 (importin alpha 8)
chrX_+_7628891 0.24 ENSMUST00000077680.10
ENSMUST00000079542.13
ENSMUST00000115679.8
ENSMUST00000137467.8
Tfe3
transcription factor E3
chr16_+_43993599 0.24 ENSMUST00000119746.8
ENSMUST00000088356.10
ENSMUST00000169582.3
Usf3
upstream transcription factor family member 3
chr11_-_106670309 0.23 ENSMUST00000021060.6
Polg2
polymerase (DNA directed), gamma 2, accessory subunit
chr8_+_91635192 0.23 ENSMUST00000211403.2
Chd9
chromodomain helicase DNA binding protein 9
chr19_-_21630078 0.23 ENSMUST00000177577.2
1110059E24Rik
RIKEN cDNA 1110059E24 gene
chr7_+_122977205 0.22 ENSMUST00000033025.7
ENSMUST00000206574.2
Lcmt1
leucine carboxyl methyltransferase 1
chr17_-_24752683 0.21 ENSMUST00000061764.14
Rab26
RAB26, member RAS oncogene family
chr2_+_180231038 0.19 ENSMUST00000029087.4
Ogfr
opioid growth factor receptor
chr12_+_49429790 0.18 ENSMUST00000021333.5
Foxg1
forkhead box G1
chr2_+_32425734 0.17 ENSMUST00000133366.2
Fam102a
family with sequence similarity 102, member A
chr10_-_81186025 0.15 ENSMUST00000122993.8
Hmg20b
high mobility group 20B
chr6_-_85938613 0.13 ENSMUST00000032071.13
Dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr12_+_49429574 0.12 ENSMUST00000179669.3
Foxg1
forkhead box G1
chr6_-_28261881 0.12 ENSMUST00000115320.8
ENSMUST00000123098.8
ENSMUST00000115321.9
ENSMUST00000155494.2
Zfp800
zinc finger protein 800
chr2_-_48839276 0.12 ENSMUST00000028098.11
Orc4
origin recognition complex, subunit 4
chr10_-_81186137 0.09 ENSMUST00000167481.8
Hmg20b
high mobility group 20B
chrX_+_99019176 0.09 ENSMUST00000113781.8
ENSMUST00000113783.8
ENSMUST00000113779.8
ENSMUST00000113776.8
ENSMUST00000113775.8
ENSMUST00000113780.8
ENSMUST00000113778.8
ENSMUST00000113777.8
ENSMUST00000071453.3
Eda
ectodysplasin-A
chr10_-_81186222 0.06 ENSMUST00000020454.11
ENSMUST00000105324.9
ENSMUST00000154609.3
ENSMUST00000105323.8
Hmg20b
high mobility group 20B
chr2_-_119308094 0.04 ENSMUST00000110808.2
ENSMUST00000049920.14
Ino80
INO80 complex subunit
chrX_+_48559327 0.02 ENSMUST00000114904.10
Arhgap36
Rho GTPase activating protein 36
chr7_+_127503812 0.02 ENSMUST00000151451.3
ENSMUST00000124533.3
ENSMUST00000206745.2
ENSMUST00000206140.2
Bckdk
branched chain ketoacid dehydrogenase kinase
chr2_+_124452493 0.01 ENSMUST00000103239.10
ENSMUST00000103240.9
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
0.6 1.7 GO:0003165 Purkinje myocyte development(GO:0003165)
0.5 2.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.5 2.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.4 1.3 GO:0048320 axial mesoderm formation(GO:0048320)
0.4 3.6 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.4 1.1 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.4 1.1 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.3 1.0 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.2 2.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.2 1.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 1.5 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.8 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 0.8 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 4.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.3 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 2.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 3.4 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 2.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133) oviduct development(GO:0060066)
0.1 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.8 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 1.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 2.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.3 GO:0003170 heart valve development(GO:0003170)
0.0 0.7 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 3.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 2.8 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0033186 CAF-1 complex(GO:0033186)
0.3 3.6 GO:0045098 type III intermediate filament(GO:0045098)
0.2 2.2 GO:0045298 tubulin complex(GO:0045298)
0.2 4.1 GO:0016600 flotillin complex(GO:0016600)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.0 GO:0089701 U2AF(GO:0089701)
0.1 2.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.8 GO:0030914 STAGA complex(GO:0030914)
0.1 1.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.0 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.6 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.7 2.8 GO:0005118 sevenless binding(GO:0005118)
0.5 3.6 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.2 GO:0070773 protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
0.3 1.1 GO:0070052 collagen V binding(GO:0070052)
0.3 0.8 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.2 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 4.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.0 GO:0050733 RS domain binding(GO:0050733)
0.1 0.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.0 GO:0051400 BH domain binding(GO:0051400)
0.1 0.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 1.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.7 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 2.8 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.8 GO:0051219 phosphoprotein binding(GO:0051219)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling