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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Elf3

Z-value: 1.34

Motif logo

Transcription factors associated with Elf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000003051.14 Elf3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Elf3mm39_v1_chr1_-_135186176_1351863060.706.2e-12Click!

Activity profile of Elf3 motif

Sorted Z-values of Elf3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_165957784 11.52 ENSMUST00000060833.14
glycoprotein A33 (transmembrane)
chr7_-_3680530 10.68 ENSMUST00000038743.15
transmembrane channel-like gene family 4
chr8_-_65582206 10.62 ENSMUST00000098713.5
small integral membrane protein 31
chr19_-_11058452 9.90 ENSMUST00000025636.8
membrane-spanning 4-domains, subfamily A, member 8A
chr7_+_130633776 9.27 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr17_+_35268942 8.57 ENSMUST00000007257.10
chloride intracellular channel 1
chr2_+_151414524 8.52 ENSMUST00000028950.9
syndecan binding protein (syntenin) 2
chr11_+_115778427 8.35 ENSMUST00000167507.3
myosin XVB
chr9_-_76474374 8.13 ENSMUST00000183437.8
family with sequence similarity 83, member B
chr6_+_60921456 7.73 ENSMUST00000129603.4
ENSMUST00000204333.2
multimerin 1
chr1_+_165957909 7.47 ENSMUST00000166159.2
glycoprotein A33 (transmembrane)
chr1_-_87029312 6.62 ENSMUST00000113270.3
alkaline phosphatase, intestinal
chr10_-_117128763 6.42 ENSMUST00000092162.7
lysozyme 1
chr10_+_34359395 6.36 ENSMUST00000019913.15
fyn-related kinase
chr7_+_30463175 6.25 ENSMUST00000165887.8
ENSMUST00000085691.11
ENSMUST00000054427.13
ENSMUST00000085688.11
dermokine
chr3_-_92833537 6.17 ENSMUST00000067318.6
late cornified envelope 3A
chr10_+_34359513 6.08 ENSMUST00000170771.3
fyn-related kinase
chr7_+_24476597 6.07 ENSMUST00000038069.9
ENSMUST00000206847.2
carcinoembryonic antigen-related cell adhesion molecule 10
chr19_+_34044745 5.78 ENSMUST00000025682.12
ENSMUST00000126710.8
lipase, family member N
chr2_-_119060366 5.65 ENSMUST00000076084.6
protein phosphatase 1, regulatory inhibitor subunit 14D
chr7_+_30475819 5.47 ENSMUST00000041703.10
dermokine
chr6_-_86770504 5.45 ENSMUST00000204441.3
ENSMUST00000204398.2
ENSMUST00000001187.15
annexin A4
chr1_-_136158027 5.38 ENSMUST00000150163.8
ENSMUST00000144464.7
innate immunity activator
chr16_+_92295009 5.28 ENSMUST00000023670.4
chloride intracellular channel 6
chr10_-_117074501 5.18 ENSMUST00000159193.8
ENSMUST00000020392.5
RIKEN cDNA 9530003J23 gene
chr13_+_120085355 5.08 ENSMUST00000099241.4
chemokine (C-C motif) ligand 28
chrX_+_162922317 4.96 ENSMUST00000112271.10
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr8_+_75599801 4.90 ENSMUST00000034034.10
intestine specific homeobox
chr2_-_119060330 4.90 ENSMUST00000110820.3
protein phosphatase 1, regulatory inhibitor subunit 14D
chr3_+_92874366 4.86 ENSMUST00000098886.5
late cornified envelope 3E
chr7_+_141988714 4.77 ENSMUST00000118276.8
ENSMUST00000105976.8
ENSMUST00000097939.9
synaptotagmin VIII
chr14_+_80237691 4.65 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr3_-_30067537 4.64 ENSMUST00000108270.10
MDS1 and EVI1 complex locus
chr16_+_96001650 4.52 ENSMUST00000048770.16
SH3-binding domain glutamic acid-rich protein
chr5_+_37892863 4.49 ENSMUST00000073554.4
cytokine-like 1
chr4_+_135413593 4.47 ENSMUST00000074408.7
interferon lambda receptor 1
chr6_+_113448388 4.44 ENSMUST00000058300.14
interleukin 17 receptor C
chr10_-_62067026 4.41 ENSMUST00000047883.11
tetraspanin 15
chr15_+_79400597 4.36 ENSMUST00000010974.9
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr18_-_9619460 4.36 ENSMUST00000234003.2
ENSMUST00000062769.7
centrin 1
chr2_+_24105430 4.30 ENSMUST00000028361.5
interleukin 1 family, member 6
chr16_+_92282593 4.04 ENSMUST00000162181.8
chloride intracellular channel 6
chr5_+_17779273 4.01 ENSMUST00000030568.14
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_103235475 3.97 ENSMUST00000041385.14
Rho GTPase activating protein 27
chr14_-_70761507 3.80 ENSMUST00000022692.5
surfactant associated protein C
chr1_-_133834790 3.62 ENSMUST00000149380.8
ENSMUST00000124051.9
opticin
chr11_-_69576363 3.56 ENSMUST00000018896.14
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_92366022 3.46 ENSMUST00000058142.4
small proline-rich protein 3
chr1_-_133617824 3.36 ENSMUST00000189524.2
ENSMUST00000169295.8
lymphocyte transmembrane adaptor 1
chr5_+_115680964 3.35 ENSMUST00000137716.8
paxillin
chr19_-_40982576 3.32 ENSMUST00000117695.8
B cell linker
chr4_-_14621805 3.30 ENSMUST00000042221.14
solute carrier family 26, member 7
chr7_-_101582987 3.27 ENSMUST00000106964.8
ENSMUST00000106963.2
ENSMUST00000078448.11
ENSMUST00000106966.8
leucine rich repeat containing 51
chr2_+_164404499 3.26 ENSMUST00000017867.10
ENSMUST00000109344.9
ENSMUST00000109345.9
WAP four-disulfide core domain 2
chr3_+_90511068 3.24 ENSMUST00000001046.7
S100 calcium binding protein A4
chr11_+_73068063 3.18 ENSMUST00000108477.2
Tax1 (human T cell leukemia virus type I) binding protein 3
chr7_+_126808016 3.16 ENSMUST00000206204.2
ENSMUST00000206772.2
myosin light chain, phosphorylatable, fast skeletal muscle
chrX_+_106860083 3.15 ENSMUST00000143975.8
ENSMUST00000144695.8
ENSMUST00000167154.2
terminal nucleotidyltransferase 5D
chr3_+_92864693 3.07 ENSMUST00000059053.11
late cornified envelope 3D
chr3_+_84573499 2.98 ENSMUST00000107682.2
transmembrane protein 154
chr11_+_78811613 2.91 ENSMUST00000018610.7
nitric oxide synthase 2, inducible
chr11_-_120971954 2.87 ENSMUST00000106120.3
ENSMUST00000100126.9
ENSMUST00000106119.9
secreted and transmembrane 1A
chr16_+_9988080 2.73 ENSMUST00000121292.8
ENSMUST00000044103.6
ribosomal protein L39-like
chr3_+_146205562 2.73 ENSMUST00000090031.12
ENSMUST00000118280.2
guanine nucleotide binding protein (G protein), gamma 5
chr8_-_123302187 2.68 ENSMUST00000213062.2
adenine phosphoribosyl transferase
chr13_-_74956924 2.66 ENSMUST00000223206.2
calpastatin
chr3_-_84489783 2.64 ENSMUST00000107687.9
ENSMUST00000098990.10
ADP-ribosylation factor interacting protein 1
chr1_+_40363701 2.63 ENSMUST00000095020.9
ENSMUST00000194296.6
interleukin 1 receptor-like 2
chrX_+_138511360 2.59 ENSMUST00000113026.2
ring finger protein 128
chr7_-_25176959 2.44 ENSMUST00000098668.3
ENSMUST00000206687.2
ENSMUST00000206676.2
ENSMUST00000205308.2
ENSMUST00000098669.8
ENSMUST00000206171.2
ENSMUST00000098666.9
carcinoembryonic antigen-related cell adhesion molecule 1
chr12_-_65219328 2.41 ENSMUST00000124201.2
ENSMUST00000052201.9
ENSMUST00000222244.2
ENSMUST00000221296.2
MIS18 binding protein 1
chr7_+_141040988 2.33 ENSMUST00000053670.12
calcium release activated channel regulator 2B
chr16_+_48692976 2.31 ENSMUST00000065666.6
resistin like gamma
chr3_-_89325594 2.31 ENSMUST00000029679.4
CDC28 protein kinase 1b
chr9_-_114393406 2.30 ENSMUST00000111816.3
tripartite motif-containing 71
chr4_-_14621669 2.19 ENSMUST00000143105.2
solute carrier family 26, member 7
chr3_-_52012462 2.19 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr7_-_25239229 2.17 ENSMUST00000044547.10
ENSMUST00000066503.14
ENSMUST00000064862.13
carcinoembryonic antigen-related cell adhesion molecule 2
chr4_-_156312996 2.16 ENSMUST00000105571.4
pleckstrin homology domain containing, family N member 1
chr11_+_32483290 2.14 ENSMUST00000102821.4
serine/threonine kinase 10
chr17_+_25690538 2.14 ENSMUST00000234449.2
ENSMUST00000025002.3
ENSMUST00000235033.2
tektin 4
chr13_+_13612136 2.11 ENSMUST00000005532.9
nidogen 1
chr10_-_23662948 2.05 ENSMUST00000220070.2
ribosomal protein S12
chr11_-_120971984 2.00 ENSMUST00000026162.12
secreted and transmembrane 1A
chrX_+_11184495 1.99 ENSMUST00000179859.2
H2A histone family member L1G
chr11_-_117670430 1.90 ENSMUST00000143406.8
transmembrane channel-like gene family 6
chr7_+_143027473 1.90 ENSMUST00000052348.12
solute carrier family 22 (organic cation transporter), member 18
chr6_+_70648743 1.90 ENSMUST00000103401.3
immunoglobulin kappa variable 3-4
chr16_-_43836681 1.86 ENSMUST00000036174.10
GRAM domain containing 1C
chr5_+_143166759 1.86 ENSMUST00000031574.10
speedy/RINGO cell cycle regulator family, member E4B
chr6_+_83214357 1.85 ENSMUST00000039212.8
ENSMUST00000113899.8
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr9_+_110867807 1.83 ENSMUST00000197575.2
lactotransferrin
chr4_-_156312961 1.83 ENSMUST00000217885.2
pleckstrin homology domain containing, family N member 1
chr1_+_58841650 1.83 ENSMUST00000165549.8
caspase 8
chr3_-_146205429 1.82 ENSMUST00000029839.11
spermatogenesis associated 1
chr11_+_119205613 1.80 ENSMUST00000053245.7
caspase recruitment domain family, member 14
chr11_+_53660834 1.79 ENSMUST00000108920.10
ENSMUST00000140866.9
ENSMUST00000108922.9
interferon regulatory factor 1
chr8_+_126721878 1.79 ENSMUST00000046765.10
potassium channel, subfamily K, member 1
chr2_+_144665576 1.78 ENSMUST00000028918.4
SCP2 sterol-binding domain containing 1
chr2_+_153621851 1.78 ENSMUST00000126656.4
EF-hand calcium binding domain 8
chr7_-_143294051 1.78 ENSMUST00000119499.8
oxysterol binding protein-like 5
chr18_+_35347983 1.78 ENSMUST00000235449.2
ENSMUST00000235269.2
catenin (cadherin associated protein), alpha 1
chr9_-_108140925 1.77 ENSMUST00000171412.7
ENSMUST00000195429.6
ENSMUST00000080435.9
dystroglycan 1
chr1_-_130557349 1.77 ENSMUST00000142416.2
ENSMUST00000039862.11
ENSMUST00000128128.8
zona pellucida 3 receptor
chr9_-_119019450 1.76 ENSMUST00000093775.12
solute carrier family 22 (organic cation transporter), member 14
chr2_-_29641647 1.76 ENSMUST00000129574.3
predicted gene 13420
chr2_-_84545504 1.76 ENSMUST00000035840.6
zinc finger, DHHC domain containing 5
chr3_+_85946145 1.75 ENSMUST00000238331.2
SH3 domain protein D19
chr11_+_77656414 1.75 ENSMUST00000164315.2
myosin XVIIIA
chr8_-_89362745 1.72 ENSMUST00000034087.9
sorting nexin 20
chr1_-_36578439 1.72 ENSMUST00000191849.6
predicted gene, 42417
chr1_-_186947618 1.71 ENSMUST00000110945.4
ENSMUST00000183931.8
ENSMUST00000027908.13
spermatogenesis associated 17
chr17_+_28491085 1.70 ENSMUST00000169040.3
peroxisome proliferator activator receptor delta
chr11_+_49554430 1.69 ENSMUST00000043873.10
ENSMUST00000076006.5
secretoglobin, family 3A, member 1
chr6_+_48963795 1.68 ENSMUST00000037696.6
seminal vesicle secretory protein 1
chr6_+_17636979 1.68 ENSMUST00000015877.14
ENSMUST00000152005.3
capping protein (actin filament) muscle Z-line, alpha 2
chr1_+_58834532 1.66 ENSMUST00000027189.15
caspase 8
chr2_+_68966125 1.65 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr4_-_14621497 1.65 ENSMUST00000149633.2
solute carrier family 26, member 7
chr8_-_83129832 1.65 ENSMUST00000034148.7
interleukin 15
chr9_-_50657800 1.64 ENSMUST00000239417.2
ENSMUST00000034564.4
RIKEN cDNA 2310030G06 gene
chr5_+_115681003 1.64 ENSMUST00000157050.8
paxillin
chr3_+_89325750 1.64 ENSMUST00000039110.12
ENSMUST00000125036.8
ENSMUST00000191485.7
ENSMUST00000154791.8
src homology 2 domain-containing transforming protein C1
chr16_+_48637219 1.63 ENSMUST00000023328.8
resistin like beta
chr19_-_57227742 1.62 ENSMUST00000111559.8
actin-binding LIM protein 1
chr8_+_126722113 1.61 ENSMUST00000212831.2
potassium channel, subfamily K, member 1
chr1_+_58841808 1.60 ENSMUST00000190213.2
caspase 8
chr6_+_21986445 1.60 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr9_+_44990447 1.59 ENSMUST00000050020.8
junction adhesion molecule like
chr5_+_145063568 1.56 ENSMUST00000138922.2
actin related protein 2/3 complex, subunit 1B
chr1_-_156936197 1.56 ENSMUST00000187546.7
ENSMUST00000118207.8
ENSMUST00000027884.13
ENSMUST00000121911.8
testis expressed 35
chr11_+_109253598 1.55 ENSMUST00000106702.4
ENSMUST00000020930.14
guanine nucleotide binding protein, alpha 13
chr4_-_92035446 1.55 ENSMUST00000107108.8
ENSMUST00000143542.2
IZUMO family member 3
chr11_+_53661251 1.53 ENSMUST00000138913.8
ENSMUST00000123376.8
ENSMUST00000019043.13
ENSMUST00000133291.3
interferon regulatory factor 1
chr11_-_94673526 1.53 ENSMUST00000100554.8
transmembrane protein 92
chr3_-_85909798 1.53 ENSMUST00000061343.4
protease, serine 48
chr14_+_32713349 1.52 ENSMUST00000120866.8
ENSMUST00000120588.8
leucine rich repeat containing 18
chr17_+_88976088 1.51 ENSMUST00000024970.11
ENSMUST00000161481.2
general transcription factor IIA, 1-like
chr10_+_79824418 1.51 ENSMUST00000004784.11
ENSMUST00000105374.2
calponin 2
chr9_-_67739607 1.49 ENSMUST00000054500.7
C2 calcium-dependent domain containing 4A
chr7_-_79882228 1.46 ENSMUST00000123279.8
calcium and integrin binding 1 (calmyrin)
chr17_+_13574834 1.44 ENSMUST00000233944.2
ENSMUST00000097403.4
t-complex protein 10c
chr9_+_45014092 1.43 ENSMUST00000217074.2
junction adhesion molecule like
chr18_+_50411431 1.42 ENSMUST00000039121.4
ENSMUST00000238078.2
family with sequence similarity 170, member A
chr1_-_186947651 1.40 ENSMUST00000183819.8
spermatogenesis associated 17
chr7_+_119393210 1.40 ENSMUST00000033218.15
ENSMUST00000106520.9
RNA exonuclease 5
chr8_+_72943455 1.40 ENSMUST00000072097.14
hematopoietic SH2 domain containing
chr1_+_136395673 1.39 ENSMUST00000189413.7
ENSMUST00000047817.12
kinesin family member 14
chr1_-_22386016 1.39 ENSMUST00000164877.8
regulating synaptic membrane exocytosis 1
chr17_+_7592045 1.39 ENSMUST00000095726.11
ENSMUST00000128533.8
ENSMUST00000129709.8
ENSMUST00000147803.8
ENSMUST00000140192.8
ENSMUST00000138222.8
ENSMUST00000144861.2
t-complex protein 10a
chr19_+_29923182 1.36 ENSMUST00000025724.9
interleukin 33
chr14_+_32713387 1.35 ENSMUST00000123822.8
ENSMUST00000120951.2
leucine rich repeat containing 18
chr12_-_113649535 1.35 ENSMUST00000103449.4
ENSMUST00000195707.3
immunoglobulin heavy variable 2-5
chr3_-_122778052 1.33 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr12_+_105651643 1.33 ENSMUST00000051934.7
GSK3B interacting protein
chr15_-_83316995 1.33 ENSMUST00000165095.9
protein kinase C and casein kinase substrate in neurons 2
chr6_-_128277701 1.32 ENSMUST00000143004.2
ENSMUST00000006311.13
ENSMUST00000112157.4
ENSMUST00000133118.2
TEA domain family member 4
chr16_+_19578981 1.32 ENSMUST00000079780.10
ENSMUST00000164397.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr11_-_55310724 1.31 ENSMUST00000108858.8
ENSMUST00000141530.2
secreted acidic cysteine rich glycoprotein
chr15_-_83317020 1.31 ENSMUST00000231184.2
protein kinase C and casein kinase substrate in neurons 2
chr11_-_83540175 1.31 ENSMUST00000001008.6
chemokine (C-C motif) ligand 3
chr5_+_124577952 1.31 ENSMUST00000059580.11
lysine methyltransferase 5A
chr7_-_25089522 1.31 ENSMUST00000054301.14
lipase, hormone sensitive
chr15_-_76079891 1.30 ENSMUST00000023226.13
plectin
chr19_+_4198615 1.30 ENSMUST00000123874.8
ENSMUST00000008893.9
ENSMUST00000237125.2
coronin, actin binding protein 1B
chr1_+_84817547 1.29 ENSMUST00000097672.4
F-box protein 36
chr7_+_130179063 1.27 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr17_-_40630096 1.26 ENSMUST00000026498.5
cysteine-rich secretory protein 1
chrX_+_11165496 1.26 ENSMUST00000188439.2
H2A histone family member L1A
chr3_+_108444837 1.26 ENSMUST00000029485.6
RIKEN cDNA 1700013F07 gene
chr1_+_16758629 1.26 ENSMUST00000026881.11
lymphocyte antigen 96
chr2_-_25086810 1.25 ENSMUST00000081869.7
torsin family 4, member A
chr8_+_93687561 1.25 ENSMUST00000072939.8
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr19_+_40648182 1.24 ENSMUST00000112231.9
ENSMUST00000127828.8
ectonucleoside triphosphate diphosphohydrolase 1
chr18_+_4165832 1.24 ENSMUST00000025076.10
lysozyme-like 1
chr2_-_120119544 1.24 ENSMUST00000094665.5
phospholipase A2, group IVD
chr11_-_121009503 1.23 ENSMUST00000039146.4
testis expressed gene 19.2
chr16_+_19578945 1.22 ENSMUST00000121344.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chrX_+_9150003 1.21 ENSMUST00000073949.4
H2A histone family member L1M
chr5_-_124018055 1.18 ENSMUST00000164267.2
hydrocarboxylic acid receptor 1
chr1_+_58834621 1.16 ENSMUST00000191201.7
caspase 8
chr9_-_119169053 1.15 ENSMUST00000035092.7
myeloid differentiation primary response gene 88
chrX_+_11178173 1.12 ENSMUST00000178979.2
H2A histone family member L1E
chr2_-_72810782 1.12 ENSMUST00000102689.10
trans-acting transcription factor 3
chr5_+_115567644 1.11 ENSMUST00000150779.8
musashi RNA-binding protein 1
chr14_-_54491365 1.09 ENSMUST00000128231.2
defender against cell death 1
chr3_+_89325901 1.09 ENSMUST00000128238.8
ENSMUST00000107417.9
src homology 2 domain-containing transforming protein C1
chr2_+_153816842 1.08 ENSMUST00000109753.3
BPI fold containing family A, member 6
chr14_+_32713336 1.08 ENSMUST00000038956.12
leucine rich repeat containing 18
chr14_+_54701594 1.07 ENSMUST00000022782.10
low-density lipoprotein receptor-related protein 10
chr5_+_14075281 1.04 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_34050038 1.03 ENSMUST00000084734.11
sperm acrosome associated 1
chr18_+_56565188 1.02 ENSMUST00000070166.6
GRAM domain containing 3
chr7_+_119393312 1.01 ENSMUST00000084644.3
RNA exonuclease 5
chr7_+_130467564 1.00 ENSMUST00000075181.11
ENSMUST00000151119.9
ENSMUST00000048180.12
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_44152524 1.00 ENSMUST00000212185.2
a disintegrin and metallopeptidase domain 34
chr2_-_25086770 1.00 ENSMUST00000142857.2
ENSMUST00000137920.2
torsin family 4, member A
chr3_+_87826834 1.00 ENSMUST00000137775.2
mitochondrial ribosomal protein L24
chr2_-_60793536 0.99 ENSMUST00000028347.13
RNA binding motif, single stranded interacting protein 1
chr11_-_59118988 0.99 ENSMUST00000163300.8
ENSMUST00000061242.8
ADP-ribosylation factor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.7 GO:1903575 cornified envelope assembly(GO:1903575)
1.6 4.9 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
1.3 5.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.2 5.0 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.2 3.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.9 2.8 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.8 3.3 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.8 14.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.8 7.1 GO:0019532 oxalate transport(GO:0019532)
0.7 5.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.7 2.7 GO:0046083 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.7 2.7 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.6 4.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 1.8 GO:0021682 nerve maturation(GO:0021682)
0.6 1.7 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.6 2.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.6 1.7 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.5 2.1 GO:0080154 regulation of fertilization(GO:0080154)
0.5 4.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 2.9 GO:1990839 response to endothelin(GO:1990839)
0.5 4.4 GO:0035696 monocyte extravasation(GO:0035696)
0.5 3.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.5 1.4 GO:0033624 cerebellar cortex structural organization(GO:0021698) regulation of Rap protein signal transduction(GO:0032487) negative regulation of integrin activation(GO:0033624)
0.4 6.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 1.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 2.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 0.7 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.4 1.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.0 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.3 1.6 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.3 1.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.3 8.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 1.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 0.9 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 4.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 1.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.1 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.3 1.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 1.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.3 1.8 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 2.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 17.0 GO:0018149 peptide cross-linking(GO:0018149)
0.2 2.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.2 1.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.2 17.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 4.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 0.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 4.7 GO:0002385 mucosal immune response(GO:0002385)
0.2 1.2 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 3.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.6 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.2 0.7 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.2 2.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.2 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 0.5 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 2.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.6 GO:0070836 caveola assembly(GO:0070836)
0.2 4.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.5 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 1.4 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
0.2 0.5 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 2.7 GO:0007343 egg activation(GO:0007343)
0.1 5.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.7 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 0.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 2.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 2.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0045212 neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.1 1.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 4.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 0.2 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 1.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 2.2 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.0 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 2.6 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 5.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.5 GO:0042117 monocyte activation(GO:0042117)
0.1 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.1 0.5 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.5 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Fc-epsilon receptor signaling pathway(GO:0038095) Kit signaling pathway(GO:0038109)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 6.9 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 2.1 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 3.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 7.6 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.9 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 6.1 GO:0030317 sperm motility(GO:0030317)
0.1 0.6 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0009955 adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 1.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 1.2 GO:0015874 norepinephrine transport(GO:0015874)
0.0 1.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 1.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 2.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 1.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 1.0 GO:0006301 postreplication repair(GO:0006301)
0.0 1.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 1.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 6.7 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 1.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 2.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 2.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.7 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 4.2 GO:0007596 blood coagulation(GO:0007596)
0.0 6.2 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.5 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.5 GO:0071773 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0032532 regulation of microvillus length(GO:0032532)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.9 6.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.9 2.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.8 9.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 2.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.7 3.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 1.8 GO:0043159 acrosomal matrix(GO:0043159)
0.4 1.6 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 3.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 6.5 GO:0042581 specific granule(GO:0042581)
0.3 17.0 GO:0001533 cornified envelope(GO:0001533)
0.3 1.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 2.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 18.4 GO:0034707 chloride channel complex(GO:0034707)
0.2 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.8 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.9 GO:0005915 zonula adherens(GO:0005915)
0.1 3.4 GO:0005605 basal lamina(GO:0005605)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 2.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 6.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 10.1 GO:0042641 actomyosin(GO:0042641)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 3.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 8.1 GO:0005903 brush border(GO:0005903)
0.0 3.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 2.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 7.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 3.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 5.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.7 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 11.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 54.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
3.1 9.3 GO:0035375 zymogen binding(GO:0035375)
2.0 8.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.6 6.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.2 5.0 GO:0051435 BH4 domain binding(GO:0051435)
0.9 6.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.9 2.7 GO:0002055 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.9 4.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.8 2.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.8 5.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.8 14.8 GO:0003796 lysozyme activity(GO:0003796)
0.8 3.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.7 2.9 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.7 2.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6 1.7 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.6 1.7 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.5 1.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.5 4.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 3.9 GO:0043237 laminin-1 binding(GO:0043237)
0.5 4.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.5 2.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 1.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.4 7.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.4 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 2.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 1.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.1 GO:0070976 TIR domain binding(GO:0070976)
0.3 5.1 GO:0038191 neuropilin binding(GO:0038191)
0.2 3.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 4.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.2 10.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 0.6 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.2 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 1.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 4.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.8 GO:0051373 FATZ binding(GO:0051373)
0.2 6.4 GO:0008009 chemokine activity(GO:0008009)
0.2 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 11.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 4.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 9.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 3.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0045159 myosin II binding(GO:0045159)
0.1 4.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.9 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 1.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.8 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 2.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.9 GO:0042166 acetylcholine binding(GO:0042166)
0.0 2.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 9.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 6.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0048038 quinone binding(GO:0048038)
0.0 1.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 8.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 3.6 GO:0005125 cytokine activity(GO:0005125)
0.0 11.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.2 GO:0032934 sterol binding(GO:0032934)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 5.1 GO:0045296 cadherin binding(GO:0045296)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.4 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.7 GO:0003774 motor activity(GO:0003774)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 7.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 20.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 3.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 5.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 3.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 4.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 3.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 4.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 10.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 8.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 3.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease