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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Erg

Z-value: 3.02

Motif logo

Transcription factors associated with Erg

Gene Symbol Gene ID Gene Info
ENSMUSG00000040732.21 Erg

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ergmm39_v1_chr16_-_95260104_952602430.733.1e-13Click!

Activity profile of Erg motif

Sorted Z-values of Erg motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Erg

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_19801781 25.87 ENSMUST00000058839.10
kelch-like 6
chr10_-_81335966 24.30 ENSMUST00000053646.7
sphingosine-1-phosphate receptor 4
chr1_+_130793406 22.48 ENSMUST00000038829.7
Fc fragment of IgM receptor
chr19_-_11243530 22.20 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr7_+_24596806 18.70 ENSMUST00000003469.8
CD79A antigen (immunoglobulin-associated alpha)
chr3_-_90603013 18.42 ENSMUST00000069960.12
ENSMUST00000117167.2
S100 calcium binding protein A9 (calgranulin B)
chr1_-_133617824 18.02 ENSMUST00000189524.2
ENSMUST00000169295.8
lymphocyte transmembrane adaptor 1
chr7_-_125968653 17.33 ENSMUST00000205642.2
ENSMUST00000032997.8
ENSMUST00000206793.2
linker for activation of T cells
chr16_+_36755338 16.75 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr7_-_83304698 15.96 ENSMUST00000145610.8
interleukin 16
chr3_+_90511068 15.66 ENSMUST00000001046.7
S100 calcium binding protein A4
chr10_+_5543769 15.62 ENSMUST00000051809.10
myc target 1
chr9_+_21437440 15.51 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chr11_-_106278892 15.17 ENSMUST00000106813.9
ENSMUST00000141146.2
intercellular adhesion molecule 2
chr15_-_66432938 15.14 ENSMUST00000048372.7
transmembrane protein 71
chr14_+_40853734 15.09 ENSMUST00000022314.10
ENSMUST00000170719.2
surfactant associated protein A1
chr6_-_16898440 14.97 ENSMUST00000031533.11
transcription factor EC
chr14_+_44340111 14.96 ENSMUST00000074839.7
eosinophil-associated, ribonuclease A family, member 2
chr4_-_129467430 14.41 ENSMUST00000102596.8
lymphocyte protein tyrosine kinase
chrX_+_47235313 14.38 ENSMUST00000033427.7
SAM and SH3 domain containing 3
chr2_-_148285450 14.33 ENSMUST00000099269.4
CD93 antigen
chr7_-_126817639 14.00 ENSMUST00000152267.8
ENSMUST00000106314.8
septin 1
chr6_-_129449739 13.58 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr5_-_140986312 13.55 ENSMUST00000085786.7
caspase recruitment domain family, member 11
chr16_-_95260104 13.51 ENSMUST00000176345.10
ENSMUST00000121809.11
ENSMUST00000233664.2
ENSMUST00000122199.10
ETS transcription factor
chr14_-_32907023 13.46 ENSMUST00000130509.10
ENSMUST00000061753.15
WD repeat and FYVE domain containing 4
chr7_+_126895463 13.43 ENSMUST00000106306.9
ENSMUST00000120857.8
integrin alpha L
chr6_-_48685108 13.39 ENSMUST00000126422.3
ENSMUST00000119315.2
ENSMUST00000053661.7
GTPase, IMAP family member 6
chr17_+_28426752 13.03 ENSMUST00000002327.6
ENSMUST00000233560.2
ENSMUST00000233958.2
ENSMUST00000233170.2
differentially expressed in FDCP 6
chr1_+_40554513 12.86 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chrX_-_9335525 12.76 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr14_+_51366512 12.75 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr9_+_7445822 12.56 ENSMUST00000034497.8
matrix metallopeptidase 3
chr11_-_106606076 12.51 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
platelet/endothelial cell adhesion molecule 1
chr1_-_192883743 12.30 ENSMUST00000043550.11
TRAF3 interacting protein 3
chr14_-_44057096 12.16 ENSMUST00000100691.4
eosinophil-associated, ribonuclease A family, member 1
chr3_+_84573499 12.00 ENSMUST00000107682.2
transmembrane protein 154
chr10_-_62343516 11.66 ENSMUST00000020271.13
serglycin
chr9_+_123902143 11.65 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr7_-_126736979 11.50 ENSMUST00000049931.6
sialophorin
chr1_-_192883642 11.47 ENSMUST00000192020.6
TRAF3 interacting protein 3
chr7_-_126817475 11.41 ENSMUST00000106313.8
ENSMUST00000142356.3
septin 1
chr2_+_103800459 11.30 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr10_+_127157784 11.12 ENSMUST00000219511.2
Rho GTPase activating protein 9
chr6_+_48715971 11.04 ENSMUST00000054368.7
ENSMUST00000140054.3
ENSMUST00000204168.2
ENSMUST00000204408.2
GTPase, IMAP family member 1
predicted gene, 28053
chr10_+_127159609 11.02 ENSMUST00000069548.7
Rho GTPase activating protein 9
chr17_+_48666919 10.85 ENSMUST00000224001.2
ENSMUST00000024792.8
ENSMUST00000225849.2
triggering receptor expressed on myeloid cells-like 1
chr14_-_70761507 10.85 ENSMUST00000022692.5
surfactant associated protein C
chr10_+_127159568 10.84 ENSMUST00000219026.2
Rho GTPase activating protein 9
chr13_-_41640757 10.81 ENSMUST00000021794.14
neural precursor cell expressed, developmentally down-regulated gene 9
chr2_+_103800553 10.64 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr3_-_95799242 10.64 ENSMUST00000171519.2
ENSMUST00000036360.13
ENSMUST00000090476.10
cDNA sequence BC028528
chr2_+_29968596 10.61 ENSMUST00000045246.8
protein kinase N3
chr11_-_106605772 10.43 ENSMUST00000124958.3
platelet/endothelial cell adhesion molecule 1
chr16_+_57369595 10.38 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr6_+_60921456 10.33 ENSMUST00000129603.4
ENSMUST00000204333.2
multimerin 1
chr11_+_61544085 10.25 ENSMUST00000004959.3
GRB2-related adaptor protein
chr9_+_55997246 10.15 ENSMUST00000059206.8
proline-serine-threonine phosphatase-interacting protein 1
chr1_+_170104889 10.10 ENSMUST00000179976.3
SH2 domain containing 1B1
chr7_-_30741532 10.09 ENSMUST00000160689.8
ENSMUST00000202395.4
ENSMUST00000162733.8
ENSMUST00000162087.8
ENSMUST00000009831.14
FXYD domain-containing ion transport regulator 5
chr2_+_32536594 10.01 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr14_+_71011744 9.95 ENSMUST00000022698.8
docking protein 2
chr1_-_131127825 9.92 ENSMUST00000068564.15
Ras association (RalGDS/AF-6) domain family member 5
chrX_-_7956682 9.72 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr11_+_61376257 9.66 ENSMUST00000064783.10
ENSMUST00000040522.7
microfibrillar-associated protein 4
chr14_-_122153185 9.59 ENSMUST00000055475.9
G protein-coupled receptor 18
chr4_-_129452148 9.52 ENSMUST00000167288.8
ENSMUST00000134336.3
lymphocyte protein tyrosine kinase
chr7_-_30741497 9.49 ENSMUST00000162116.8
ENSMUST00000159924.8
FXYD domain-containing ion transport regulator 5
chr1_-_54965470 9.42 ENSMUST00000179030.8
ENSMUST00000044359.16
ankyrin repeat domain 44
chr7_+_126895423 9.40 ENSMUST00000117762.8
integrin alpha L
chr10_-_75776437 9.38 ENSMUST00000219979.2
predicted gene 867
chr8_-_89362745 9.32 ENSMUST00000034087.9
sorting nexin 20
chr1_+_171216480 9.30 ENSMUST00000056449.9
Rho GTPase activating protein 30
chr17_-_32622525 9.24 ENSMUST00000135618.8
ENSMUST00000063824.14
RAS protein activator like 3
chr13_-_37234213 9.23 ENSMUST00000164727.8
coagulation factor XIII, A1 subunit
chr16_-_45940602 9.22 ENSMUST00000023336.10
CD96 antigen
chr2_-_164198427 9.20 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr11_-_52173391 9.19 ENSMUST00000086844.10
transcription factor 7, T cell specific
chr4_-_129452180 9.14 ENSMUST00000067240.11
lymphocyte protein tyrosine kinase
chr4_+_126042250 9.14 ENSMUST00000106150.3
eva-1 homolog B (C. elegans)
chr14_-_44112974 9.08 ENSMUST00000179200.2
eosinophil-associated, ribonuclease A family, member 1
chr9_-_44920899 9.08 ENSMUST00000102832.3
CD3 antigen, epsilon polypeptide
chr9_-_88613967 8.99 ENSMUST00000098486.4
B cell leukemia/lymphoma 2 related protein A1d
chr2_+_164897547 8.96 ENSMUST00000017799.12
ENSMUST00000073707.9
CD40 antigen
chr18_-_35873493 8.92 ENSMUST00000235495.2
ENSMUST00000237919.2
ENSMUST00000237405.2
stimulator of interferon response cGAMP interactor 1
chr3_+_137046828 8.84 ENSMUST00000122064.8
ENSMUST00000119475.6
endomucin
chr11_+_49554430 8.81 ENSMUST00000043873.10
ENSMUST00000076006.5
secretoglobin, family 3A, member 1
chr7_-_30119227 8.78 ENSMUST00000208740.2
ENSMUST00000075062.5
hematopoietic cell signal transducer
chr2_+_164897583 8.77 ENSMUST00000081310.11
ENSMUST00000140951.8
CD40 antigen
chr7_-_30741762 8.67 ENSMUST00000161684.8
FXYD domain-containing ion transport regulator 5
chr7_-_30741237 8.62 ENSMUST00000161805.8
FXYD domain-containing ion transport regulator 5
chr19_-_4240984 8.62 ENSMUST00000045864.4
TBC1 domain family, member 10c
chr3_-_10273628 8.55 ENSMUST00000029041.6
fatty acid binding protein 4, adipocyte
chr1_+_135060431 8.48 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr3_-_130524024 8.48 ENSMUST00000079085.11
ribosomal protein L34
chr6_-_136918495 8.37 ENSMUST00000111892.8
Rho, GDP dissociation inhibitor (GDI) beta
chr9_+_89081262 8.35 ENSMUST00000068569.5
B cell leukemia/lymphoma 2 related protein A1b
chr7_-_30741512 8.32 ENSMUST00000159753.2
FXYD domain-containing ion transport regulator 5
chr19_-_4241034 8.25 ENSMUST00000237495.2
TBC1 domain family, member 10c
chr16_+_44586085 8.14 ENSMUST00000057488.15
CD200 receptor 1
chr7_+_126895531 8.11 ENSMUST00000170971.8
integrin alpha L
chr7_-_44180700 8.07 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr17_+_43700327 8.06 ENSMUST00000113599.2
ENSMUST00000224278.2
ENSMUST00000225466.2
adhesion G protein-coupled receptor F5
chr16_+_17615146 8.06 ENSMUST00000012161.5
ENSMUST00000232577.2
scavenger receptor class F, member 2
chr3_-_20296337 8.00 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr3_+_137046935 8.00 ENSMUST00000197511.2
endomucin
chr1_-_80643024 8.00 ENSMUST00000187774.7
dedicator of cytokinesis 10
chr12_-_58315949 7.97 ENSMUST00000062254.4
C-type lectin domain family 14, member a
chr17_-_32622497 7.91 ENSMUST00000137458.2
RAS protein activator like 3
chr4_-_63321591 7.84 ENSMUST00000035724.5
AT-hook transcription factor
chr6_+_87755046 7.84 ENSMUST00000032133.5
glycoprotein 9 (platelet)
chr8_+_70261323 7.81 ENSMUST00000036074.15
ENSMUST00000123453.2
Gem-interacting protein
chr1_-_80642969 7.74 ENSMUST00000190983.7
ENSMUST00000191449.2
dedicator of cytokinesis 10
chr1_-_170755136 7.69 ENSMUST00000046322.14
ENSMUST00000159171.2
Fc receptor-like A
chr12_+_98234884 7.67 ENSMUST00000075072.6
G-protein coupled receptor 65
chr8_+_93687561 7.58 ENSMUST00000072939.8
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr17_+_43671314 7.56 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr19_+_6451667 7.56 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr17_+_75742881 7.55 ENSMUST00000164192.9
RAS, guanyl releasing protein 3
chr1_+_152683627 7.52 ENSMUST00000027754.7
neutrophil cytosolic factor 2
chr17_-_18104182 7.43 ENSMUST00000061516.8
formyl peptide receptor 1
chr19_-_5518515 7.40 ENSMUST00000236256.2
ENSMUST00000025844.6
cathepsin W
chr8_+_89015705 7.39 ENSMUST00000171456.9
adenylate cyclase 7
chr7_+_101043568 7.39 ENSMUST00000098243.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_+_88838953 7.38 ENSMUST00000098485.4
B cell leukemia/lymphoma 2 related protein A1a
chrX_+_106299484 7.38 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr18_-_35873554 7.35 ENSMUST00000115728.5
stimulator of interferon response cGAMP interactor 1
chr11_-_72441054 7.34 ENSMUST00000021154.7
spinster homolog 3
chr10_-_18887701 7.33 ENSMUST00000105527.2
tumor necrosis factor, alpha-induced protein 3
chr7_+_28488380 7.30 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr10_+_61133549 7.27 ENSMUST00000219375.2
perforin 1 (pore forming protein)
chr3_-_130523954 7.21 ENSMUST00000196202.5
ENSMUST00000133802.6
ENSMUST00000062601.14
ENSMUST00000200517.2
ribosomal protein L34
chr13_+_55517545 7.13 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr5_-_113788451 7.13 ENSMUST00000047936.13
chemokine-like receptor 1
chr10_+_28544356 7.09 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
thymocyte selection associated
chr6_+_4003904 7.09 ENSMUST00000031670.10
guanine nucleotide binding protein (G protein), gamma 11
chr1_-_106641940 6.92 ENSMUST00000112751.2
B cell leukemia/lymphoma 2
chr8_-_71964379 6.91 ENSMUST00000048452.6
plasmalemma vesicle associated protein
chr3_+_87754310 6.89 ENSMUST00000029709.7
SH2 domain containing 2A
chr7_+_141040988 6.88 ENSMUST00000053670.12
calcium release activated channel regulator 2B
chr10_+_58207229 6.86 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr15_-_9529898 6.85 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr1_+_135060994 6.84 ENSMUST00000167080.3
protein tyrosine phosphatase, non-receptor type 7
chr3_+_87754057 6.81 ENSMUST00000107581.9
SH2 domain containing 2A
chr18_-_35873257 6.78 ENSMUST00000235302.2
stimulator of interferon response cGAMP interactor 1
chr4_-_118346952 6.77 ENSMUST00000184261.8
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_21986445 6.75 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr11_-_79421397 6.66 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr13_-_55677109 6.66 ENSMUST00000223563.2
docking protein 3
chrX_+_158623460 6.65 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr2_+_118428690 6.65 ENSMUST00000038341.8
BUB1B, mitotic checkpoint serine/threonine kinase
chr7_+_43086432 6.64 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr17_-_52133594 6.62 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr13_+_102830029 6.60 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr9_+_123901979 6.53 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr4_-_127207773 6.51 ENSMUST00000053753.8
gap junction protein, alpha 4
chr11_-_103235475 6.48 ENSMUST00000041385.14
Rho GTPase activating protein 27
chr11_-_103254257 6.48 ENSMUST00000092557.6
Rho GTPase activating protein 27
chr1_-_156301821 6.44 ENSMUST00000188027.2
ENSMUST00000187507.7
ENSMUST00000189661.7
sterol O-acyltransferase 1
chr9_+_110709353 6.44 ENSMUST00000155014.2
ALS2 C-terminal like
chr1_+_159871943 6.43 ENSMUST00000163892.8
RIKEN cDNA 4930523C07 gene
chr11_-_46203047 6.38 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr2_+_84670956 6.38 ENSMUST00000111625.2
solute carrier family 43, member 1
chr6_-_136918671 6.36 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_52091156 6.35 ENSMUST00000169070.2
ENSMUST00000074477.7
eosinophil-associated, ribonuclease A family, member 6
chr9_+_99333474 6.29 ENSMUST00000163199.5
NME/NM23 family member 9
chr1_+_152683568 6.25 ENSMUST00000190323.7
neutrophil cytosolic factor 2
chr18_-_14815807 6.24 ENSMUST00000040964.13
ENSMUST00000234524.2
ENSMUST00000092041.11
ENSMUST00000040924.9
SS18, nBAF chromatin remodeling complex subunit
chr17_+_33743144 6.22 ENSMUST00000087623.13
ENSMUST00000234715.2
ENSMUST00000234497.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
chr2_-_31973795 6.22 ENSMUST00000056406.7
family with sequence similarity 78, member A
chr2_+_84670543 6.21 ENSMUST00000111624.8
solute carrier family 43, member 1
chr16_+_95058417 6.15 ENSMUST00000113861.8
ENSMUST00000113854.8
ENSMUST00000113862.8
ENSMUST00000037154.14
ENSMUST00000113855.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_+_104828253 6.14 ENSMUST00000034339.10
cadherin 5
chr2_-_73284262 6.13 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chrX_+_158086253 6.12 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr7_-_143294051 6.07 ENSMUST00000119499.8
oxysterol binding protein-like 5
chr14_+_51366306 6.06 ENSMUST00000226210.2
ribonuclease, RNase A family, 6
chr9_-_66826928 6.06 ENSMUST00000041139.9
RAB8B, member RAS oncogene family
chr2_+_26473870 5.98 ENSMUST00000100290.13
ENSMUST00000238983.2
ENSMUST00000102907.13
EGF-like domain 7
chr3_+_103767581 5.97 ENSMUST00000029433.9
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr2_+_164790139 5.92 ENSMUST00000017881.3
matrix metallopeptidase 9
chr7_-_132415257 5.92 ENSMUST00000097999.9
family with sequence similarity 53, member B
chr7_+_98138904 5.91 ENSMUST00000205956.2
leucine rich repeat containing 32
chr3_+_88523440 5.87 ENSMUST00000177498.8
ENSMUST00000176500.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr6_-_123266820 5.87 ENSMUST00000032239.11
ENSMUST00000177367.8
C-type lectin domain family 4, member e
chr3_-_14843512 5.74 ENSMUST00000094365.11
carbonic anhydrase 1
chr6_+_129374441 5.71 ENSMUST00000112081.9
ENSMUST00000112079.3
C-type lectin domain family 1, member b
chrX_+_163156359 5.69 ENSMUST00000033751.8
vascular endothelial growth factor D
chr11_+_89921121 5.68 ENSMUST00000092788.4
transmembrane protein 100
chr2_+_33106062 5.67 ENSMUST00000004208.7
angiopoietin-like 2
chr4_-_118347249 5.65 ENSMUST00000047421.6
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_+_43086554 5.64 ENSMUST00000206741.2
natural killer cell group 7 sequence
chr17_+_47908025 5.63 ENSMUST00000183206.2
cyclin D3
chr2_-_92876398 5.59 ENSMUST00000111272.3
ENSMUST00000178666.8
ENSMUST00000147339.3
PR domain containing 11
chr4_-_43558386 5.57 ENSMUST00000130353.2
talin 1
chr16_+_10297923 5.56 ENSMUST00000230395.2
class II transactivator
chrX_+_152506577 5.55 ENSMUST00000140575.8
ENSMUST00000208373.2
ENSMUST00000185492.7
ENSMUST00000149514.8
negative regulator of P-body association
chr6_-_131224305 5.55 ENSMUST00000032306.15
ENSMUST00000088867.7
killer cell lectin-like receptor, subfamily A, member 2
chr19_+_41017714 5.50 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr9_-_20888054 5.50 ENSMUST00000054197.7
sphingosine-1-phosphate receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.9 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
6.1 18.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
6.1 18.2 GO:0090265 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
4.1 16.6 GO:0033374 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
3.8 11.5 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
3.4 30.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.4 10.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
3.3 10.0 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
3.2 9.7 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
3.2 9.6 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
3.1 9.4 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
3.1 12.2 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
2.9 11.6 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807)
2.6 2.6 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
2.5 33.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
2.5 10.1 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
2.4 9.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
2.3 6.9 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
2.3 13.8 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
2.1 6.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.1 12.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
2.0 14.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
2.0 5.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.9 16.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.8 5.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
1.8 5.3 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
1.7 10.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.7 13.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.7 10.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.7 26.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
1.6 14.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.6 4.9 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.6 12.8 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
1.5 4.6 GO:0021759 globus pallidus development(GO:0021759)
1.5 9.1 GO:0006742 NADP catabolic process(GO:0006742)
1.5 4.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.5 4.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.5 23.7 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
1.4 4.3 GO:1904093 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
1.4 9.8 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.4 19.4 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
1.4 6.9 GO:0014042 positive regulation of neuron maturation(GO:0014042)
1.4 4.1 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
1.4 15.1 GO:0008228 opsonization(GO:0008228)
1.4 21.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.4 4.1 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
1.3 4.0 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of T cell migration(GO:2000405)
1.3 5.4 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
1.3 6.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.3 6.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
1.3 3.9 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
1.3 5.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.3 10.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.3 2.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.3 12.6 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.3 5.0 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.2 7.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.2 17.3 GO:0006968 cellular defense response(GO:0006968)
1.2 15.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.2 27.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.2 9.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
1.2 15.6 GO:0043031 negative regulation of macrophage activation(GO:0043031) positive regulation of phospholipid biosynthetic process(GO:0071073)
1.1 6.9 GO:0034436 glycoprotein transport(GO:0034436)
1.1 6.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.1 11.3 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346)
1.1 2.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
1.1 3.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
1.1 7.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.1 22.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
1.1 3.2 GO:1903699 tarsal gland development(GO:1903699)
1.1 4.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
1.0 16.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.0 4.8 GO:0031296 B cell costimulation(GO:0031296)
0.9 3.8 GO:0016240 autophagosome docking(GO:0016240) zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.9 3.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.9 4.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.9 9.2 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) embryonic genitalia morphogenesis(GO:0030538) T cell receptor V(D)J recombination(GO:0033153)
0.9 3.6 GO:0017126 nucleologenesis(GO:0017126)
0.9 5.3 GO:0040010 positive regulation of growth rate(GO:0040010)
0.9 28.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.9 2.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.9 5.2 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.9 29.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.9 4.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.8 5.9 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.8 15.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.8 3.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.8 18.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.8 9.7 GO:0048251 UV protection(GO:0009650) elastic fiber assembly(GO:0048251)
0.8 26.5 GO:0002467 germinal center formation(GO:0002467)
0.8 4.8 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.8 8.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.8 9.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.8 2.3 GO:0061010 gall bladder development(GO:0061010)
0.8 11.5 GO:0051709 regulation of killing of cells of other organism(GO:0051709)
0.8 6.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.7 2.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.7 2.9 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.7 2.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 2.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.7 2.9 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.7 3.6 GO:1901355 response to rapamycin(GO:1901355)
0.7 1.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 5.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.7 6.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.7 10.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.7 4.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.7 2.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.7 8.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.7 2.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 12.1 GO:0043383 negative T cell selection(GO:0043383)
0.7 2.6 GO:0090309 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 3.3 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6 8.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.6 3.2 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.6 8.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.6 4.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.6 5.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.6 6.9 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.6 1.9 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.6 6.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.6 3.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.6 2.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 4.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 1.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 4.8 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.6 8.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 3.0 GO:0002159 desmosome assembly(GO:0002159)
0.6 8.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.6 2.3 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.6 2.8 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.6 3.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.5 2.7 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.5 7.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 3.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.5 8.9 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.5 4.0 GO:0006868 glutamine transport(GO:0006868)
0.5 3.4 GO:2000138 positive regulation of skeletal muscle tissue growth(GO:0048633) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.5 2.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 1.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 3.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.4 41.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.4 1.7 GO:0032672 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068) interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.4 2.6 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.4 4.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.4 1.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 4.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.4 8.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.4 5.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 3.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 7.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 3.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.4 1.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 1.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.3 6.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 6.6 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 15.7 GO:0045026 plasma membrane fusion(GO:0045026)
0.3 6.5 GO:0015874 norepinephrine transport(GO:0015874)
0.3 2.0 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.3 1.3 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.3 2.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 2.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 1.0 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.3 3.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 3.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 10.2 GO:0001945 lymph vessel development(GO:0001945)
0.3 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.3 8.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 2.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 1.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 24.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.3 2.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.3 1.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 12.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 1.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.3 2.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.3 4.7 GO:0016322 neuron remodeling(GO:0016322)
0.3 7.7 GO:0010447 response to acidic pH(GO:0010447)
0.3 12.7 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.3 33.7 GO:0030183 B cell differentiation(GO:0030183)
0.3 0.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 3.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 2.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.3 6.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 9.6 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 8.0 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.3 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.3 7.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 5.8 GO:0030225 macrophage differentiation(GO:0030225)
0.3 3.8 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.3 3.3 GO:0002507 tolerance induction(GO:0002507)
0.2 1.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.2 1.5 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.2 6.7 GO:0030220 platelet formation(GO:0030220)
0.2 0.7 GO:0046038 GMP catabolic process(GO:0046038)
0.2 4.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 0.7 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 25.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.2 0.9 GO:0009257 histidine biosynthetic process(GO:0000105) 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 0.9 GO:0090400 stress-induced premature senescence(GO:0090400)
0.2 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 0.7 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 14.5 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.6 GO:0021553 olfactory nerve development(GO:0021553)
0.2 1.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 3.5 GO:0042730 fibrinolysis(GO:0042730)
0.2 1.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 2.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 1.6 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.2 3.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 5.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.2 2.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 4.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 3.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.2 1.7 GO:0038203 TORC2 signaling(GO:0038203)
0.2 5.5 GO:0033198 response to ATP(GO:0033198)
0.2 28.4 GO:0007596 blood coagulation(GO:0007596)
0.2 6.9 GO:0043029 T cell homeostasis(GO:0043029)
0.2 1.6 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 6.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 4.9 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 3.3 GO:0042554 superoxide anion generation(GO:0042554)
0.2 6.0 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.2 2.0 GO:0046697 decidualization(GO:0046697)
0.2 3.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 2.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.5 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.2 3.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 1.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 4.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 2.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 24.0 GO:0042113 B cell activation(GO:0042113)
0.1 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.7 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 5.4 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 1.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 2.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.5 GO:1990839 response to endothelin(GO:1990839)
0.1 3.2 GO:0046040 IMP metabolic process(GO:0046040)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.0 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 5.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 7.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 23.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 5.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 4.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 5.1 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.6 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 4.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 2.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 15.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 6.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.8 GO:0015809 arginine transport(GO:0015809)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 6.1 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 17.6 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.2 GO:0080009 mRNA methylation(GO:0080009)
0.1 5.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.3 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.1 10.7 GO:0010631 epithelial cell migration(GO:0010631)
0.1 2.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 4.4 GO:0007032 endosome organization(GO:0007032)
0.1 3.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 4.3 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 2.0 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 9.2 GO:0000910 cytokinesis(GO:0000910)
0.1 0.5 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 2.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 6.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 2.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 2.1 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0051715 cytolysis in other organism(GO:0051715)
0.1 2.2 GO:0035904 aorta development(GO:0035904)
0.1 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 1.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 2.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 3.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 4.5 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 2.8 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.5 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 2.7 GO:0006497 protein lipidation(GO:0006497)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 15.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 5.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.9 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 1.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 2.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0007099 centriole replication(GO:0007099)
0.0 0.4 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 6.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.3 GO:0021549 cerebellum development(GO:0021549)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 30.9 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
2.5 22.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.5 7.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
2.3 22.9 GO:0019815 B cell receptor complex(GO:0019815)
1.9 9.7 GO:0071953 elastic fiber(GO:0071953)
1.9 9.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.9 29.8 GO:0043020 NADPH oxidase complex(GO:0043020)
1.7 5.2 GO:0005607 laminin-2 complex(GO:0005607)
1.7 29.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.7 10.1 GO:0005826 actomyosin contractile ring(GO:0005826)
1.5 16.6 GO:0042629 mast cell granule(GO:0042629)
1.5 7.3 GO:0044194 cytolytic granule(GO:0044194)
1.4 7.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
1.4 40.4 GO:0042101 T cell receptor complex(GO:0042101)
1.3 5.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.2 35.8 GO:0000242 pericentriolar material(GO:0000242)
1.1 3.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.0 4.0 GO:0060171 stereocilium membrane(GO:0060171)
1.0 5.0 GO:0045160 myosin I complex(GO:0045160)
1.0 16.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.9 3.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.8 8.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.7 4.5 GO:0042583 chromaffin granule(GO:0042583)
0.7 3.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.7 10.2 GO:0016589 NURF complex(GO:0016589)
0.7 15.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 2.8 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.7 4.1 GO:0005683 U7 snRNP(GO:0005683)
0.6 4.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.6 3.0 GO:0005914 spot adherens junction(GO:0005914)
0.6 20.0 GO:0031527 filopodium membrane(GO:0031527)
0.6 2.3 GO:0061689 tricellular tight junction(GO:0061689)
0.5 27.2 GO:0008180 COP9 signalosome(GO:0008180)
0.5 12.6 GO:0031091 platelet alpha granule(GO:0031091)
0.5 3.4 GO:0097443 sorting endosome(GO:0097443)
0.5 6.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.5 4.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 27.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.4 9.8 GO:0005922 connexon complex(GO:0005922)
0.4 2.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 15.1 GO:0005771 multivesicular body(GO:0005771)
0.3 2.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 5.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 0.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.3 1.5 GO:1990130 Iml1 complex(GO:1990130)
0.3 4.4 GO:0005915 zonula adherens(GO:0005915)
0.3 7.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 0.8 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 4.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 16.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 1.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 4.8 GO:0036038 MKS complex(GO:0036038)
0.3 1.9 GO:0036396 MIS complex(GO:0036396)
0.2 6.2 GO:0071564 npBAF complex(GO:0071564)
0.2 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.2 9.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 4.3 GO:0001891 phagocytic cup(GO:0001891)
0.2 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 130.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 3.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.2 16.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 14.0 GO:0000791 euchromatin(GO:0000791)
0.2 5.2 GO:0005605 basal lamina(GO:0005605)
0.2 43.1 GO:0005884 actin filament(GO:0005884)
0.2 3.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 2.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 17.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 6.6 GO:0097440 apical dendrite(GO:0097440)
0.2 42.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 1.8 GO:0000815 ESCRT III complex(GO:0000815)
0.2 8.2 GO:0031901 early endosome membrane(GO:0031901)
0.2 13.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 28.8 GO:0001726 ruffle(GO:0001726)
0.1 3.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 75.2 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 16.8 GO:0016605 PML body(GO:0016605)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 28.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 16.2 GO:0000922 spindle pole(GO:0000922)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.0 GO:0030897 HOPS complex(GO:0030897)
0.1 0.5 GO:0034448 EGO complex(GO:0034448)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 1.5 GO:0031011 Ino80 complex(GO:0031011)
0.1 3.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 17.4 GO:0005911 cell-cell junction(GO:0005911)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 2.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 5.5 GO:0016459 myosin complex(GO:0016459)
0.1 1.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 43.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.1 8.4 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 21.8 GO:0005925 focal adhesion(GO:0005925)
0.1 6.9 GO:0005912 adherens junction(GO:0005912)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 6.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 21.3 GO:0009986 cell surface(GO:0009986)
0.1 5.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 5.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 43.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 5.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 15.6 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 33.1 GO:0042610 CD8 receptor binding(GO:0042610)
6.2 30.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
6.1 18.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
4.2 41.5 GO:0050786 RAGE receptor binding(GO:0050786)
2.5 7.6 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
2.3 6.9 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
2.1 29.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.9 30.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.9 13.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.8 14.3 GO:0001849 complement component C1q binding(GO:0001849)
1.8 5.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.8 16.0 GO:0042609 CD4 receptor binding(GO:0042609)
1.7 7.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.6 14.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 7.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.3 33.0 GO:0051400 BH domain binding(GO:0051400)
1.3 10.0 GO:0005534 galactose binding(GO:0005534)
1.2 13.6 GO:0050700 CARD domain binding(GO:0050700)
1.2 7.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.2 6.1 GO:0030911 TPR domain binding(GO:0030911)
1.1 15.2 GO:0030274 LIM domain binding(GO:0030274)
1.0 4.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
1.0 4.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.0 4.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.0 5.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 12.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
1.0 3.8 GO:0070051 fibrinogen binding(GO:0070051)
0.9 4.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.9 3.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.9 7.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.9 22.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.8 5.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8 5.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 3.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.8 7.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.8 7.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.8 8.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 2.3 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.8 4.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.7 9.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.7 2.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.7 2.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 2.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.7 5.4 GO:0051425 PTB domain binding(GO:0051425)
0.7 10.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 36.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.6 2.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.6 10.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.6 1.8 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.6 2.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.6 5.7 GO:0004064 arylesterase activity(GO:0004064)
0.6 5.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.6 2.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.6 4.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.6 1.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.5 45.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 7.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 4.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 9.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.5 2.0 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.5 36.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 5.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 28.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 64.4 GO:0004540 ribonuclease activity(GO:0004540)
0.5 1.8 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.4 13.4 GO:0043274 phospholipase binding(GO:0043274)
0.4 6.7 GO:0051525 NFAT protein binding(GO:0051525)
0.4 2.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 1.7 GO:0019767 IgE receptor activity(GO:0019767)
0.4 7.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 10.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 14.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 2.4 GO:0048495 Roundabout binding(GO:0048495)
0.4 13.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.4 11.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 8.5 GO:0004697 protein kinase C activity(GO:0004697)
0.4 18.0 GO:0042169 SH2 domain binding(GO:0042169)
0.4 2.1 GO:0019961 interferon binding(GO:0019961)
0.3 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.3 10.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 24.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 37.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 2.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 7.3 GO:0022829 wide pore channel activity(GO:0022829)
0.3 19.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 64.8 GO:0017124 SH3 domain binding(GO:0017124)
0.3 2.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 4.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 3.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 10.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 4.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 14.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 10.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 6.0 GO:0017166 vinculin binding(GO:0017166)
0.3 3.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 1.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.3 8.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.7 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 91.5 GO:0005096 GTPase activator activity(GO:0005096)
0.2 2.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 3.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.7 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.2 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 2.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 5.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 20.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 4.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 2.9 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.2 3.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 9.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.2 1.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 23.6 GO:0008013 beta-catenin binding(GO:0008013)
0.2 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.2 20.8 GO:0005178 integrin binding(GO:0005178)
0.2 2.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.8 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 11.7 GO:0005518 collagen binding(GO:0005518)
0.2 0.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 2.3 GO:0008301 DNA binding, bending(GO:0008301)
0.2 5.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 12.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 1.4 GO:0031432 titin binding(GO:0031432)
0.2 10.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.2 3.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 8.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 4.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.5 GO:0050733 RS domain binding(GO:0050733)
0.1 4.5 GO:0005112 Notch binding(GO:0005112)
0.1 4.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 5.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 8.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 12.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 6.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.9 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 4.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.7 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 17.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 3.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 8.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 6.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.5 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 7.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 16.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 6.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 3.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 11.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 7.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 7.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.9 GO:0019843 rRNA binding(GO:0019843)
0.1 3.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.2 GO:0017022 myosin binding(GO:0017022)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 2.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 3.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 9.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 6.8 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.8 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 7.3 GO:0005525 GTP binding(GO:0005525)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.1 GO:0004386 helicase activity(GO:0004386)
0.0 1.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0004519 endonuclease activity(GO:0004519)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 49.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.2 12.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.2 84.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.1 24.7 PID S1P S1P4 PATHWAY S1P4 pathway
1.1 15.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.1 17.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.0 51.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.0 27.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.9 100.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.9 5.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.8 65.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.8 32.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.8 27.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.8 11.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 28.3 PID CD40 PATHWAY CD40/CD40L signaling
0.7 8.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.7 4.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.7 27.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.7 8.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.6 8.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6 19.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 12.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.6 23.7 PID BCR 5PATHWAY BCR signaling pathway
0.6 32.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.6 7.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 7.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 25.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.5 20.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 9.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.4 11.9 PID ALK1 PATHWAY ALK1 signaling events
0.4 2.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 5.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 7.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 15.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 9.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 7.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 13.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 10.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.3 55.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 14.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 2.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 8.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 3.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 4.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 20.3 PID CMYB PATHWAY C-MYB transcription factor network
0.2 8.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 2.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 7.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 14.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 14.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 7.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 5.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 4.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.7 PID AURORA B PATHWAY Aurora B signaling
0.1 21.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.7 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 49.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.0 18.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
1.7 98.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.2 12.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.0 11.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.0 3.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.0 22.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.9 24.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.9 21.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 24.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.8 12.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.8 41.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.8 10.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.8 7.5 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.8 4.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.7 8.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.7 9.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 11.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 18.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 7.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6 10.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.5 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.5 7.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.5 2.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 27.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.4 25.0 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.4 7.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 9.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 14.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 14.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 9.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.4 8.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 7.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 10.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 37.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 26.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.3 8.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 15.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 6.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 62.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 25.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 3.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 4.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 45.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 9.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 10.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 2.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.7 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.2 6.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 11.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 2.3 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 1.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 6.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 6.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 9.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 6.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors