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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Esrrb_Esrra

Z-value: 3.06

Motif logo

Transcription factors associated with Esrrb_Esrra

Gene Symbol Gene ID Gene Info
ENSMUSG00000021255.18 Esrrb
ENSMUSG00000024955.16 Esrra

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esrramm39_v1_chr19_-_6899173_68992080.531.8e-06Click!
Esrrbmm39_v1_chr12_+_86468401_864684360.422.4e-04Click!

Activity profile of Esrrb_Esrra motif

Sorted Z-values of Esrrb_Esrra motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrb_Esrra

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_141009264 71.96 ENSMUST00000164387.2
ENSMUST00000137488.2
ENSMUST00000084436.10
cell cycle exit and neuronal differentiation 1
chr7_-_141009346 60.17 ENSMUST00000124444.2
cell cycle exit and neuronal differentiation 1
chr19_-_43512929 41.30 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr15_-_83989801 40.82 ENSMUST00000229826.2
ENSMUST00000082365.6
sulfotransferase family 4A, member 1
chr2_+_121188195 38.95 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr15_-_74624811 35.16 ENSMUST00000189128.2
ENSMUST00000023259.15
Ly6/neurotoxin 1
chr2_+_121189091 32.06 ENSMUST00000000317.13
ENSMUST00000129130.3
creatine kinase, mitochondrial 1, ubiquitous
chr18_+_77273510 31.75 ENSMUST00000075290.8
ENSMUST00000079618.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_+_102536701 30.74 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_+_79552421 29.34 ENSMUST00000099513.8
ENSMUST00000020581.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr8_+_95498822 27.57 ENSMUST00000211956.2
ENSMUST00000211947.2
chemokine (C-X3-C motif) ligand 1
chr15_+_74435587 27.09 ENSMUST00000185682.7
ENSMUST00000170845.8
ENSMUST00000187599.2
adhesion G protein-coupled receptor B1
chr12_-_11485639 26.77 ENSMUST00000220506.2
visinin-like 1
chr12_+_102521225 25.29 ENSMUST00000021610.7
chromogranin A
chr15_-_79688910 23.50 ENSMUST00000175858.10
ENSMUST00000023057.10
neuronal pentraxin receptor
chr15_+_82140224 23.47 ENSMUST00000143238.2
RIKEN cDNA 1500009C09 gene
chr8_+_94879235 22.89 ENSMUST00000034211.10
ENSMUST00000211930.2
ENSMUST00000211915.2
metallothionein 3
chr17_+_44263890 22.11 ENSMUST00000177857.9
ENSMUST00000044792.6
regulator of calcineurin 2
chr11_-_4045343 21.89 ENSMUST00000004868.6
mitochondrial fission process 1
chr18_+_45402018 20.81 ENSMUST00000183850.8
ENSMUST00000066890.14
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr11_-_3454766 20.71 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr1_-_175319842 20.52 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr2_+_121125918 20.47 ENSMUST00000110639.8
microtubule-associated protein 1 A
chr2_+_177760959 20.39 ENSMUST00000108916.8
phosphatase and actin regulator 3
chr19_-_5135510 20.39 ENSMUST00000140389.8
ENSMUST00000151413.2
ENSMUST00000077066.8
transmembrane protein 151A
chr1_+_181180183 19.46 ENSMUST00000161880.8
ENSMUST00000027795.14
cornichon family AMPA receptor auxiliary protein 3
chr3_+_27237143 19.33 ENSMUST00000091284.5
neutral cholesterol ester hydrolase 1
chr12_-_111638722 19.20 ENSMUST00000001304.9
creatine kinase, brain
chr3_-_54823287 18.96 ENSMUST00000070342.4
serine rich and transmembrane domain containing 1
chr11_+_42310557 18.89 ENSMUST00000007797.10
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr3_+_27237114 18.79 ENSMUST00000046515.15
neutral cholesterol ester hydrolase 1
chr6_+_38639945 18.61 ENSMUST00000114874.5
C-type lectin domain family 2, member L
chr12_+_61570669 18.58 ENSMUST00000055815.14
ENSMUST00000119481.2
leucine rich repeat and fibronectin type III domain containing 5
chr9_-_70048766 18.44 ENSMUST00000034749.16
family with sequence similarity 81, member A
chr4_-_68872585 18.38 ENSMUST00000030036.6
bone morphogenic protein/retinoic acid inducible neural specific 1
chr1_-_167221344 18.20 ENSMUST00000028005.3
microsomal glutathione S-transferase 3
chr15_+_74435217 18.12 ENSMUST00000190524.7
adhesion G protein-coupled receptor B1
chr15_+_78314251 18.09 ENSMUST00000229622.2
ENSMUST00000162808.2
potassium channel tetramerisation domain containing 17
chr6_-_54543446 18.06 ENSMUST00000019268.11
secernin 1
chr11_+_7013422 17.93 ENSMUST00000020706.5
adenylate cyclase 1
chr9_-_53882530 17.56 ENSMUST00000048409.14
ELMO/CED-12 domain containing 1
chr3_-_107424637 17.45 ENSMUST00000166892.2
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_-_167030706 17.05 ENSMUST00000207917.2
potassium voltage gated channel, Shab-related subfamily, member 1
chr4_-_133225849 17.01 ENSMUST00000125541.2
TMF1-regulated nuclear protein 1
chr16_+_96081998 17.00 ENSMUST00000099497.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr16_-_28383615 16.98 ENSMUST00000231399.2
fibroblast growth factor 12
chr1_-_84673903 16.87 ENSMUST00000049126.13
delta/notch-like EGF repeat containing
chr9_-_107546166 16.70 ENSMUST00000177567.8
solute carrier family 38, member 3
chr18_-_10706701 16.39 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr19_+_8568618 16.25 ENSMUST00000170817.2
ENSMUST00000010251.11
solute carrier family 22 (organic anion transporter), member 8
chr15_+_23036535 16.15 ENSMUST00000164787.8
cadherin 18
chr11_+_3939924 16.11 ENSMUST00000109981.2
galactose-3-O-sulfotransferase 1
chr9_+_54493618 16.08 ENSMUST00000217484.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr8_-_70573465 16.01 ENSMUST00000002412.9
neurocan
chr18_-_60757272 15.94 ENSMUST00000155195.3
synaptopodin
chr11_+_98632631 15.85 ENSMUST00000064187.12
thyroid hormone receptor alpha
chr15_+_81756671 15.85 ENSMUST00000135198.2
ENSMUST00000157003.8
ENSMUST00000229068.2
aconitase 2, mitochondrial
chr6_-_113478779 15.79 ENSMUST00000101059.4
ENSMUST00000204268.3
ENSMUST00000205170.2
ENSMUST00000205075.2
ENSMUST00000204134.3
proline-rich transmembrane protein 3
chr6_-_114018982 15.76 ENSMUST00000101045.10
ATPase, Ca++ transporting, plasma membrane 2
chr4_+_130297132 15.69 ENSMUST00000105993.4
Na+/K+ transporting ATPase interacting 1
chr18_-_20879461 15.69 ENSMUST00000070080.6
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
chr11_+_83300481 15.67 ENSMUST00000175848.8
ENSMUST00000108140.10
RAS-like, family 10, member B
chr2_+_177760768 15.55 ENSMUST00000108917.8
phosphatase and actin regulator 3
chr18_-_61147272 15.55 ENSMUST00000025520.10
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr2_+_32518402 15.09 ENSMUST00000156578.8
adenylate kinase 1
chr16_+_21644692 14.98 ENSMUST00000232240.2
mitogen-activated protein kinase kinase kinase 13
chr1_+_162466717 14.95 ENSMUST00000028020.11
myocilin
chr9_+_54493784 14.74 ENSMUST00000167866.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr14_+_32043944 14.65 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr1_-_43235914 14.52 ENSMUST00000187357.2
four and a half LIM domains 2
chr16_-_43959993 14.34 ENSMUST00000137557.8
ATPase, H+ transporting, lysosomal V1 subunit A
chr11_-_41891359 14.34 ENSMUST00000070735.10
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr9_-_43027809 14.33 ENSMUST00000216126.2
ENSMUST00000213544.2
ENSMUST00000061833.6
TLC domain containing 5
chr15_-_98118858 14.08 ENSMUST00000142443.8
ENSMUST00000170618.8
predicted gene 44579
olfactory receptor 287
chr6_+_48604869 14.07 ENSMUST00000154570.2
expressed sequence AI854703
chr6_+_91134358 14.03 ENSMUST00000155007.2
histone deacetylase 11
chr1_+_34840785 14.02 ENSMUST00000047664.16
ENSMUST00000211073.2
Rho guanine nucleotide exchange factor (GEF) 4
novel protein
chr13_-_25454058 14.01 ENSMUST00000057866.13
neurensin 1
chr6_+_91133755 13.64 ENSMUST00000143621.8
histone deacetylase 11
chr5_+_63806451 13.63 ENSMUST00000159584.3
NACHT and WD repeat domain containing 2
chr17_+_17669082 13.52 ENSMUST00000140134.2
limb and CNS expressed 1
chr2_+_177783713 13.46 ENSMUST00000103066.10
phosphatase and actin regulator 3
chr5_+_118165808 13.40 ENSMUST00000031304.14
tescalcin
chr1_+_75377616 13.40 ENSMUST00000122266.3
SPEG complex locus
chr6_+_91133647 12.89 ENSMUST00000041736.11
histone deacetylase 11
chr6_+_90527762 12.75 ENSMUST00000130418.8
ENSMUST00000032175.11
ENSMUST00000203111.2
aldehyde dehydrogenase 1 family, member L1
chr11_+_5008110 12.64 ENSMUST00000037218.2
RAS-like, family 10, member A
chr9_+_107217786 12.61 ENSMUST00000042581.4
RIKEN cDNA 6430571L13 gene
chr1_+_104696235 12.56 ENSMUST00000062528.9
cadherin 20
chr16_+_17093941 12.43 ENSMUST00000164950.11
transmembrane protein 191C
chr17_-_23990512 12.29 ENSMUST00000226460.2
FLYWCH-type zinc finger 1
chr2_-_129541753 12.16 ENSMUST00000028883.12
prodynorphin
chr5_+_37242714 12.13 ENSMUST00000121010.9
ENSMUST00000174629.2
ENSMUST00000232332.3
janus kinase and microtubule interacting protein 1
predicted gene 1043
chr16_-_43959559 12.11 ENSMUST00000063661.13
ENSMUST00000114666.9
ATPase, H+ transporting, lysosomal V1 subunit A
chr5_+_57875309 12.11 ENSMUST00000191837.6
ENSMUST00000068110.10
protocadherin 7
chr11_+_68979308 11.99 ENSMUST00000021273.13
vesicle-associated membrane protein 2
chr4_-_148244028 11.99 ENSMUST00000167160.8
ENSMUST00000151246.8
F-box protein 44
chr1_+_75522902 11.76 ENSMUST00000124341.8
solute carrier family 4 (anion exchanger), member 3
chr17_-_23990479 11.68 ENSMUST00000086325.13
FLYWCH-type zinc finger 1
chr9_-_107546195 11.58 ENSMUST00000192990.6
solute carrier family 38, member 3
chr2_-_180956293 11.56 ENSMUST00000103045.4
stathmin-like 3
chr2_+_26518456 11.53 ENSMUST00000074240.4
divergent protein kinase domain 1B
chr11_+_83299963 11.32 ENSMUST00000021022.10
RAS-like, family 10, member B
chrX_-_71699740 11.23 ENSMUST00000055966.13
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr11_-_69451012 11.20 ENSMUST00000004036.6
ephrin B3
chr1_+_36730530 11.17 ENSMUST00000081180.7
ENSMUST00000193210.6
ENSMUST00000195151.6
cytochrome c oxidase subunit 5B
chr7_+_4122555 11.02 ENSMUST00000079415.12
tweety family member 1
chr11_-_115158062 10.98 ENSMUST00000106554.2
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr6_+_29853745 10.96 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr19_-_7194912 10.92 ENSMUST00000039758.6
cytochrome c oxidase subunit 8A
chr3_-_152232389 10.90 ENSMUST00000200062.2
adenylate kinase 5
chr16_-_43960045 10.86 ENSMUST00000147025.2
ATPase, H+ transporting, lysosomal V1 subunit A
chr13_-_12355604 10.69 ENSMUST00000168193.8
ENSMUST00000064204.14
actinin alpha 2
chr16_+_5703134 10.57 ENSMUST00000230658.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_20844034 10.45 ENSMUST00000226630.2
calcium/calmodulin-dependent protein kinase II gamma
chr1_-_16589425 10.44 ENSMUST00000159558.8
ENSMUST00000054668.13
ENSMUST00000162627.8
ENSMUST00000162007.8
ENSMUST00000128957.9
ENSMUST00000115359.10
ENSMUST00000151888.8
staufen double-stranded RNA binding protein 2
chr11_-_97464755 10.42 ENSMUST00000126287.2
ENSMUST00000107590.9
SRC kinase signaling inhibitor 1
chr2_-_84508385 10.41 ENSMUST00000189772.2
ENSMUST00000053664.9
ENSMUST00000111664.8
predicted gene 28635
thioredoxin-related transmembrane protein 2
chr1_+_135710803 10.37 ENSMUST00000132795.8
troponin I, skeletal, slow 1
chr2_+_140012560 10.29 ENSMUST00000044825.5
NADH:ubiquinone oxidoreductase complex assembly factor 5
chr8_+_124138163 10.29 ENSMUST00000071134.4
ENSMUST00000212743.2
tubulin, beta 3 class III
chr9_-_54568950 10.27 ENSMUST00000128624.2
acyl-CoA synthetase bubblegum family member 1
chr8_-_125296435 10.27 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr7_+_4122523 10.15 ENSMUST00000119661.8
ENSMUST00000129423.8
tweety family member 1
chr11_+_54194831 10.10 ENSMUST00000000145.12
ENSMUST00000138515.8
acyl-CoA synthetase long-chain family member 6
chr10_-_81066607 10.03 ENSMUST00000047408.6
ataxia, cerebellar, Cayman type
chr11_-_41891111 9.98 ENSMUST00000109290.2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_-_157408239 9.96 ENSMUST00000109528.9
ENSMUST00000088494.3
bladder cancer associated protein
chr7_+_91321694 9.66 ENSMUST00000238608.2
discs large MAGUK scaffold protein 2
chr3_-_36744269 9.65 ENSMUST00000029271.5
transient receptor potential cation channel, subfamily C, member 3
chr15_+_34838195 9.62 ENSMUST00000228725.2
K+ voltage-gated channel, subfamily S, 2
chr10_-_71180763 9.57 ENSMUST00000045887.9
CDGSH iron sulfur domain 1
chr5_+_150042092 9.56 ENSMUST00000200960.4
ENSMUST00000202530.4
FRY microtubule binding protein
chrX_-_94240056 9.37 ENSMUST00000200628.2
ENSMUST00000197364.5
ENSMUST00000181987.8
CDC42 guanine nucleotide exchange factor (GEF) 9
chr7_-_126398165 9.35 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr1_-_134163102 9.33 ENSMUST00000187631.2
ENSMUST00000038191.8
ENSMUST00000086465.6
adenosine A1 receptor
chr14_-_30637344 9.25 ENSMUST00000226547.2
inter-alpha trypsin inhibitor, heavy chain 3
chr10_+_94034817 9.20 ENSMUST00000020209.16
ENSMUST00000179990.8
NADH:ubiquinone oxidoreductase subunit A12
chr7_+_89281897 9.15 ENSMUST00000032856.13
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr15_+_68800261 9.09 ENSMUST00000022954.7
KH domain containing, RNA binding, signal transduction associated 3
chr1_-_135241429 9.09 ENSMUST00000134088.3
ENSMUST00000081104.10
translocase of inner mitochondrial membrane 17a
chr5_+_107645626 9.06 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr4_+_42917228 8.97 ENSMUST00000107976.9
ENSMUST00000069184.9
PHD finger protein 24
chr4_+_137408975 8.93 ENSMUST00000047243.12
Rap1 GTPase-activating protein
chr3_-_117153802 8.87 ENSMUST00000197743.2
phospholipid phosphatase related 4
chr1_-_123972900 8.86 ENSMUST00000112603.4
dipeptidylpeptidase 10
chr9_-_121621544 8.81 ENSMUST00000035110.11
hedgehog acyltransferase-like
chr16_+_39804711 8.77 ENSMUST00000187695.7
limbic system-associated membrane protein
chr11_-_11848044 8.76 ENSMUST00000066237.10
dopa decarboxylase
chr10_+_127919142 8.75 ENSMUST00000026459.6
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr1_+_134121170 8.65 ENSMUST00000038445.13
ENSMUST00000191577.2
myosin binding protein H
chr2_-_152218542 8.64 ENSMUST00000079278.5
neurensin 2
chr7_-_81356557 8.63 ENSMUST00000207983.2
homer scaffolding protein 2
chrX_-_166907286 8.62 ENSMUST00000239138.2
FERM and PDZ domain containing 4
chr4_-_131871797 8.61 ENSMUST00000056336.2
opioid receptor, delta 1
chr9_-_113855776 8.55 ENSMUST00000035090.14
F-box and leucine-rich repeat protein 2
chr3_+_32583681 8.43 ENSMUST00000147350.8
mitofusin 1
chr1_-_52230062 8.33 ENSMUST00000156887.8
ENSMUST00000129107.2
glutaminase
chr13_-_95170755 8.32 ENSMUST00000162670.8
phosphodiesterase 8B
chr11_+_54194624 8.31 ENSMUST00000093106.12
acyl-CoA synthetase long-chain family member 6
chr13_+_108350923 8.18 ENSMUST00000022207.10
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr1_-_75196496 8.17 ENSMUST00000186758.7
tubulin, alpha 4A
chr19_+_11724913 8.16 ENSMUST00000025585.4
cobalamin binding intrinsic factor
chr11_-_11848107 8.14 ENSMUST00000178704.8
dopa decarboxylase
chr16_-_91728162 7.97 ENSMUST00000139277.8
ENSMUST00000154661.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr19_-_3962733 7.96 ENSMUST00000075092.8
ENSMUST00000235847.2
ENSMUST00000235301.2
ENSMUST00000237341.2
NADH:ubiquinone oxidoreductase core subunit S8
chr4_+_137977714 7.95 ENSMUST00000105824.8
ENSMUST00000124239.8
ENSMUST00000105823.2
ENSMUST00000105818.8
SH2 domain containing 5
kinesin family member 17
chr15_+_30173197 7.91 ENSMUST00000226119.2
catenin (cadherin associated protein), delta 2
chr14_-_70867588 7.89 ENSMUST00000228009.2
dematin actin binding protein
chr13_-_25121568 7.79 ENSMUST00000037615.7
aldhehyde dehydrogenase family 5, subfamily A1
chr2_+_170573727 7.72 ENSMUST00000029075.5
docking protein 5
chr13_-_53083494 7.67 ENSMUST00000123599.8
AU RNA binding protein/enoyl-coenzyme A hydratase
chr15_+_79982033 7.63 ENSMUST00000143928.2
synaptogyrin 1
chr11_+_93886906 7.61 ENSMUST00000041956.14
sperm associated antigen 9
chr14_+_58310143 7.56 ENSMUST00000022545.14
fibroblast growth factor 9
chr13_-_74498320 7.54 ENSMUST00000221594.2
ENSMUST00000022062.8
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr7_+_29883611 7.53 ENSMUST00000208441.2
cytochrome c oxidase subunit 7A1
chr3_+_32583602 7.52 ENSMUST00000091257.11
mitofusin 1
chr5_-_9775151 7.50 ENSMUST00000004076.5
glutamate receptor, metabotropic 3
chr8_-_74080101 7.47 ENSMUST00000119826.7
ENSMUST00000212459.2
LARGE xylosyl- and glucuronyltransferase 1
chr2_-_155771938 7.40 ENSMUST00000152766.8
ENSMUST00000139232.8
ENSMUST00000109632.8
ENSMUST00000006036.13
ENSMUST00000142655.2
ENSMUST00000159238.2
ubiquinol-cytochrome c reductase complex assembly factor 1
chr2_+_129854256 7.39 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr16_-_37474772 7.37 ENSMUST00000023514.4
NADH:ubiquinone oxidoreductase subunit B4
chr2_+_91757594 7.37 ENSMUST00000045537.4
cholinergic receptor, muscarinic 4
chr2_+_32515442 7.32 ENSMUST00000113277.8
ENSMUST00000195721.6
adenylate kinase 1
chr2_+_163280375 7.30 ENSMUST00000109420.10
ENSMUST00000109421.10
ENSMUST00000018087.13
ENSMUST00000137070.2
ganglioside-induced differentiation-associated protein 1-like 1
chr19_+_4761181 7.27 ENSMUST00000008991.8
spectrin beta, non-erythrocytic 2
chr1_+_75523092 7.27 ENSMUST00000150142.8
solute carrier family 4 (anion exchanger), member 3
chr4_-_138858340 7.25 ENSMUST00000143971.2
mitochondrial contact site and cristae organizing system subunit 10
chr11_-_53321606 7.20 ENSMUST00000061326.5
ENSMUST00000109021.4
ubiquinol-cytochrome c reductase, complex III subunit VII
chr1_-_87501548 7.20 ENSMUST00000068681.12
neuronal guanine nucleotide exchange factor
chr7_-_81356653 7.16 ENSMUST00000026922.15
homer scaffolding protein 2
chr9_+_27210500 7.14 ENSMUST00000214357.2
ENSMUST00000115247.8
ENSMUST00000133213.3
immunoglobulin superfamily, member 9B
chr11_-_97466035 7.13 ENSMUST00000107596.9
ENSMUST00000238314.2
ENSMUST00000238597.2
ENSMUST00000238342.2
SRC kinase signaling inhibitor 1
chr14_-_109151590 7.12 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr9_+_55234197 7.09 ENSMUST00000085754.10
ENSMUST00000034862.5
transmembrane protein 266
chr1_-_164285914 7.04 ENSMUST00000027863.13
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_+_87864796 6.98 ENSMUST00000113607.10
ENSMUST00000049966.6
coatomer protein complex, subunit gamma 1
chr17_+_26036893 6.96 ENSMUST00000235694.2
F-box and leucine-rich repeat protein 16
chr18_+_77861656 6.94 ENSMUST00000114748.2
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
33.0 132.1 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
14.5 43.4 GO:0006106 fumarate metabolic process(GO:0006106)
9.4 28.3 GO:0006867 asparagine transport(GO:0006867) positive regulation of glutamine transport(GO:2000487)
7.6 22.7 GO:0097212 lysosomal membrane organization(GO:0097212)
6.7 27.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
6.3 25.3 GO:2000705 positive regulation of relaxation of muscle(GO:1901079) regulation of dense core granule biogenesis(GO:2000705)
5.9 29.3 GO:0071321 cellular response to cGMP(GO:0071321)
5.5 27.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
5.2 46.7 GO:0006102 isocitrate metabolic process(GO:0006102)
5.2 31.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
5.0 14.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
4.7 9.3 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
4.4 30.7 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
4.3 12.8 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
4.1 16.3 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.0 15.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
3.9 15.5 GO:0035524 proline transmembrane transport(GO:0035524)
3.8 19.1 GO:0098886 modification of dendritic spine(GO:0098886)
3.7 15.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
3.7 18.4 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
3.7 11.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
3.6 14.5 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.6 10.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
3.4 10.3 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
3.4 10.3 GO:0002019 regulation of renal output by angiotensin(GO:0002019) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
3.4 17.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
3.4 13.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
3.3 10.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
3.2 9.7 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
3.2 22.4 GO:0046103 inosine biosynthetic process(GO:0046103)
3.2 15.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
3.1 9.2 GO:0006108 malate metabolic process(GO:0006108)
2.9 8.8 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
2.6 10.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
2.6 7.8 GO:0006538 glutamate catabolic process(GO:0006538)
2.5 38.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.5 17.4 GO:0015824 proline transport(GO:0015824)
2.5 9.8 GO:0051182 coenzyme transport(GO:0051182)
2.4 16.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
2.4 9.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
2.3 11.7 GO:0006537 glutamate biosynthetic process(GO:0006537)
2.3 6.9 GO:1900063 mitochondrial membrane fission(GO:0090149) regulation of peroxisome organization(GO:1900063)
2.3 11.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.3 6.8 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.3 15.8 GO:0048840 otolith development(GO:0048840)
2.2 8.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
2.1 16.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
1.9 11.5 GO:0036394 amylase secretion(GO:0036394)
1.9 20.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.9 7.6 GO:0070650 actin filament bundle distribution(GO:0070650)
1.9 43.2 GO:0071420 cellular response to histamine(GO:0071420)
1.9 7.4 GO:0090088 dipeptide transmembrane transport(GO:0035442) oligopeptide transmembrane transport(GO:0035672) regulation of oligopeptide transport(GO:0090088) regulation of dipeptide transport(GO:0090089) positive regulation of oligopeptide transport(GO:2000878) positive regulation of dipeptide transport(GO:2000880) regulation of dipeptide transmembrane transport(GO:2001148) positive regulation of dipeptide transmembrane transport(GO:2001150)
1.8 7.4 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
1.8 16.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.8 19.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.8 17.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.7 6.8 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
1.7 8.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.6 19.8 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.6 4.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
1.6 4.9 GO:0021852 pyramidal neuron migration(GO:0021852)
1.6 40.5 GO:0007614 short-term memory(GO:0007614)
1.6 8.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.6 8.0 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.6 9.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.6 8.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.5 12.1 GO:0033058 directional locomotion(GO:0033058)
1.5 4.5 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
1.5 37.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
1.5 4.4 GO:0045204 MAPK export from nucleus(GO:0045204)
1.5 4.4 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.4 24.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.4 13.0 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.4 11.4 GO:0009644 response to high light intensity(GO:0009644)
1.4 11.2 GO:0016198 axon choice point recognition(GO:0016198)
1.4 40.3 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.4 8.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.3 4.0 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
1.3 4.0 GO:0051977 lysophospholipid transport(GO:0051977)
1.3 7.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.3 34.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.3 3.8 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
1.3 1.3 GO:0014805 smooth muscle adaptation(GO:0014805)
1.3 3.8 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.2 11.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.2 29.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
1.2 2.4 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
1.2 4.8 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
1.2 3.6 GO:1990768 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
1.2 3.5 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
1.2 4.7 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
1.2 3.5 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
1.2 8.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.1 7.8 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
1.1 6.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.1 19.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
1.1 1.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
1.1 8.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.1 4.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.1 3.2 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
1.0 3.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.0 8.3 GO:0090032 operant conditioning(GO:0035106) negative regulation of steroid hormone biosynthetic process(GO:0090032)
1.0 4.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
1.0 4.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
1.0 5.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.0 3.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
1.0 6.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.0 9.1 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.0 3.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
1.0 4.8 GO:0018343 protein farnesylation(GO:0018343)
1.0 6.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.9 3.8 GO:0000105 histidine biosynthetic process(GO:0000105)
0.9 3.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.9 13.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.9 16.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.9 20.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.9 2.6 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.9 3.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.8 5.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.8 24.5 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.8 13.2 GO:0042407 cristae formation(GO:0042407)
0.8 15.7 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.8 10.6 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 25.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8 16.9 GO:0007220 Notch receptor processing(GO:0007220)
0.8 7.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.8 3.8 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.8 9.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.8 40.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.7 17.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.7 2.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.7 7.0 GO:0051683 establishment of Golgi localization(GO:0051683)
0.7 11.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 3.5 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.7 15.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.7 13.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.7 8.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7 3.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.7 2.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.7 8.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.7 5.9 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.6 7.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.6 19.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.6 27.7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.6 7.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.6 1.9 GO:0010637 regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
0.6 5.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 7.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.6 1.8 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.6 3.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6 5.5 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.6 2.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.6 7.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.6 21.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6 5.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.6 9.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.6 24.3 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.6 5.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.6 16.3 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.5 64.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 1.6 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.5 1.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 8.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.5 9.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.5 2.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.5 32.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.5 6.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 6.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.5 1.5 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.5 18.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.5 21.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.5 12.6 GO:0097320 membrane tubulation(GO:0097320)
0.5 2.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.5 3.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.5 7.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 36.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.4 7.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.4 1.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.4 10.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 50.0 GO:0032091 negative regulation of protein binding(GO:0032091)
0.4 0.8 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.4 7.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 1.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 3.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 15.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.4 4.6 GO:0008343 adult feeding behavior(GO:0008343)
0.4 32.3 GO:0046847 filopodium assembly(GO:0046847)
0.4 7.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.4 13.4 GO:0097352 autophagosome maturation(GO:0097352)
0.4 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 1.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.4 3.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 16.2 GO:0000266 mitochondrial fission(GO:0000266)
0.3 13.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 2.3 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.3 2.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 6.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 9.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 2.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 1.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 10.0 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.3 4.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 2.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 0.8 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.3 1.3 GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902163)
0.3 1.3 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 2.9 GO:0010155 regulation of proton transport(GO:0010155)
0.3 3.6 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.3 19.3 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 2.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 2.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 2.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 8.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 8.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 1.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 1.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.2 5.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.2 3.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 4.3 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.2 5.2 GO:0003334 keratinocyte development(GO:0003334)
0.2 18.0 GO:0030641 regulation of cellular pH(GO:0030641)
0.2 0.6 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2 7.5 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.2 3.9 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.2 3.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 2.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 1.6 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.2 21.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.2 1.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 2.5 GO:0006089 lactate metabolic process(GO:0006089)
0.2 14.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 18.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.2 2.9 GO:0006308 DNA catabolic process(GO:0006308)
0.2 6.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 2.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 2.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 8.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 5.7 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 9.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.2 7.4 GO:0035315 hair cell differentiation(GO:0035315)
0.2 2.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.2 7.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 9.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 3.0 GO:0016322 neuron remodeling(GO:0016322)
0.2 4.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.2 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.8 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 11.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 6.9 GO:0043113 receptor clustering(GO:0043113)
0.1 1.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 4.1 GO:0030575 nuclear body organization(GO:0030575)
0.1 1.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 2.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 1.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 2.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 1.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 2.0 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 6.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 7.1 GO:0051693 actin filament capping(GO:0051693)
0.1 0.8 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 30.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 4.6 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 14.9 GO:0006813 potassium ion transport(GO:0006813)
0.1 1.9 GO:0002070 epithelial cell maturation(GO:0002070)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.1 2.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.8 GO:0097421 liver regeneration(GO:0097421)
0.1 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 5.0 GO:0072384 organelle transport along microtubule(GO:0072384)
0.1 17.9 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.1 2.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 11.9 GO:0071229 cellular response to acid chemical(GO:0071229)
0.1 1.5 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.7 GO:0003323 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 8.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 13.9 GO:0050890 cognition(GO:0050890)
0.1 2.5 GO:0097286 iron ion import(GO:0097286)
0.1 1.3 GO:0032272 negative regulation of protein polymerization(GO:0032272)
0.1 1.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 1.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 3.6 GO:0050808 synapse organization(GO:0050808)
0.0 14.0 GO:0007409 axonogenesis(GO:0007409)
0.0 2.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 2.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.2 GO:0061462 protein targeting to lysosome(GO:0006622) protein localization to lysosome(GO:0061462)
0.0 0.9 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.0 GO:0045333 cellular respiration(GO:0045333)
0.0 1.1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 3.9 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 5.8 GO:0006887 exocytosis(GO:0006887)
0.0 2.8 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.3 GO:0098855 HCN channel complex(GO:0098855)
4.2 21.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
4.2 25.3 GO:0042583 chromaffin granule(GO:0042583)
3.1 37.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.8 11.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
2.8 31.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
2.8 27.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.7 19.1 GO:0097444 spine apparatus(GO:0097444)
2.7 24.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.3 38.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.9 31.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
1.9 54.4 GO:1902711 GABA-A receptor complex(GO:1902711)
1.9 5.6 GO:1902912 pyruvate kinase complex(GO:1902912)
1.6 22.4 GO:0001520 outer dense fiber(GO:0001520)
1.6 7.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.5 32.9 GO:0032279 asymmetric synapse(GO:0032279)
1.5 23.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.5 10.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.4 11.1 GO:0061617 MICOS complex(GO:0061617)
1.3 5.3 GO:0032437 cuticular plate(GO:0032437)
1.3 6.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
1.3 9.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.2 3.7 GO:0043291 RAVE complex(GO:0043291)
1.2 3.6 GO:0032156 septin cytoskeleton(GO:0032156)
1.2 7.3 GO:0008091 spectrin(GO:0008091)
1.2 2.4 GO:0031673 H zone(GO:0031673)
1.1 6.8 GO:0097452 GAIT complex(GO:0097452)
1.1 15.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.1 7.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.1 14.5 GO:0090533 cation-transporting ATPase complex(GO:0090533)
1.1 1.1 GO:0098830 presynaptic endosome(GO:0098830)
1.1 7.6 GO:0097513 myosin II filament(GO:0097513)
1.1 8.6 GO:0070469 respiratory chain(GO:0070469)
1.1 16.2 GO:0008385 IkappaB kinase complex(GO:0008385)
1.1 3.2 GO:0036020 endolysosome membrane(GO:0036020)
1.0 55.3 GO:0030673 axolemma(GO:0030673)
1.0 6.0 GO:0005899 insulin receptor complex(GO:0005899)
1.0 10.7 GO:0097451 glial limiting end-foot(GO:0097451)
1.0 4.8 GO:0070069 cytochrome complex(GO:0070069)
0.9 53.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.9 16.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.9 6.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.9 8.0 GO:1990075 periciliary membrane compartment(GO:1990075)
0.9 15.0 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.9 20.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.8 21.2 GO:0044292 dendrite terminus(GO:0044292)
0.8 75.1 GO:0044455 mitochondrial membrane part(GO:0044455)
0.8 10.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.7 3.0 GO:0044316 cone cell pedicle(GO:0044316)
0.7 14.1 GO:0032982 myosin filament(GO:0032982)
0.7 7.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.7 17.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.7 7.5 GO:0097449 astrocyte projection(GO:0097449)
0.7 19.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.7 24.1 GO:0032590 dendrite membrane(GO:0032590)
0.6 16.0 GO:0032426 stereocilium tip(GO:0032426)
0.6 18.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 11.6 GO:0005861 troponin complex(GO:0005861)
0.6 51.2 GO:0043198 dendritic shaft(GO:0043198)
0.6 20.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.6 7.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.6 9.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.5 14.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 2.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 43.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 2.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.4 1.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.4 91.6 GO:0043209 myelin sheath(GO:0043209)
0.4 4.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 11.3 GO:0031430 M band(GO:0031430)
0.4 85.3 GO:0008021 synaptic vesicle(GO:0008021)
0.3 5.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 109.6 GO:0014069 postsynaptic density(GO:0014069)
0.3 39.7 GO:0043679 axon terminus(GO:0043679)
0.3 2.9 GO:0071439 clathrin complex(GO:0071439)
0.3 10.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 7.1 GO:0060077 inhibitory synapse(GO:0060077)
0.3 4.1 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 2.6 GO:0032009 early phagosome(GO:0032009)
0.3 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 4.2 GO:0031143 pseudopodium(GO:0031143)
0.3 2.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 2.1 GO:0097427 microtubule bundle(GO:0097427)
0.3 3.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 26.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 49.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 18.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 4.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.9 GO:0031672 A band(GO:0031672)
0.2 0.9 GO:0045179 apical cortex(GO:0045179)
0.2 9.6 GO:0030427 site of polarized growth(GO:0030427)
0.2 36.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 14.0 GO:0043197 dendritic spine(GO:0043197)
0.2 8.6 GO:0001533 cornified envelope(GO:0001533)
0.2 12.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 23.2 GO:0030133 transport vesicle(GO:0030133)
0.1 52.7 GO:0030425 dendrite(GO:0030425)
0.1 2.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 12.0 GO:0016234 inclusion body(GO:0016234)
0.1 51.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.0 GO:0036038 MKS complex(GO:0036038)
0.1 32.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 21.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 14.3 GO:0001726 ruffle(GO:0001726)
0.1 2.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 11.4 GO:0005802 trans-Golgi network(GO:0005802)
0.1 6.7 GO:0005882 intermediate filament(GO:0005882)
0.1 35.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 11.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 2.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 383.9 GO:0016021 integral component of membrane(GO:0016021)
0.1 1.2 GO:0005901 caveola(GO:0005901)
0.0 4.0 GO:0030017 sarcomere(GO:0030017)
0.0 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.8 41.3 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
13.1 91.9 GO:0004111 creatine kinase activity(GO:0004111)
7.8 23.5 GO:0001847 opsonin receptor activity(GO:0001847)
7.1 28.3 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
6.9 20.7 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
6.4 19.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
6.2 30.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
5.3 21.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
5.2 31.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.1 30.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
4.9 29.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
4.3 12.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
4.2 16.9 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
4.0 8.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
4.0 16.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
4.0 15.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
3.9 15.7 GO:0043532 angiostatin binding(GO:0043532)
3.7 25.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
3.5 35.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
3.1 9.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
2.9 26.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
2.8 8.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.7 8.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
2.7 8.1 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
2.7 8.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
2.6 17.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
2.5 22.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
2.5 22.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.3 15.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
2.3 15.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
2.2 38.1 GO:0042301 phosphate ion binding(GO:0042301)
2.2 64.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.2 11.1 GO:0051373 FATZ binding(GO:0051373)
2.1 15.0 GO:0032027 myosin light chain binding(GO:0032027)
2.1 6.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
2.0 6.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
2.0 27.8 GO:0004017 adenylate kinase activity(GO:0004017)
1.9 11.7 GO:0004359 glutaminase activity(GO:0004359)
1.9 9.3 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.8 7.4 GO:0072541 peroxynitrite reductase activity(GO:0072541)
1.8 7.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.8 14.4 GO:0001515 opioid peptide activity(GO:0001515)
1.7 29.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.7 10.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.7 6.8 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.7 5.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
1.7 33.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.7 13.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.6 4.9 GO:0070279 vitamin B6 binding(GO:0070279)
1.6 11.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.6 15.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.5 18.4 GO:0015266 protein channel activity(GO:0015266)
1.5 16.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
1.4 14.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.4 35.6 GO:0004890 GABA-A receptor activity(GO:0004890)
1.4 8.5 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.3 3.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.3 5.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.2 30.8 GO:0050811 GABA receptor binding(GO:0050811)
1.2 8.6 GO:0004985 opioid receptor activity(GO:0004985)
1.2 9.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.2 37.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.2 4.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.2 3.6 GO:0031768 ghrelin receptor binding(GO:0031768)
1.1 3.4 GO:0016015 morphogen activity(GO:0016015)
1.1 15.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.1 5.6 GO:0004743 pyruvate kinase activity(GO:0004743)
1.1 46.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.1 11.8 GO:0070061 fructose binding(GO:0070061)
1.1 4.3 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.1 6.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.0 9.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.0 3.0 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
1.0 5.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.0 21.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.0 3.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.0 22.4 GO:0016805 dipeptidase activity(GO:0016805)
1.0 5.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
1.0 6.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.0 3.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 17.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.9 3.8 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.9 3.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.9 14.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9 4.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 21.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.9 6.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.9 6.9 GO:0001595 angiotensin receptor activity(GO:0001595)
0.9 3.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.9 20.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.8 9.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.8 4.1 GO:0016499 orexin receptor activity(GO:0016499)
0.8 5.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.8 9.8 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.8 9.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.8 11.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.8 3.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.8 4.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 7.5 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.7 7.4 GO:0004064 arylesterase activity(GO:0004064)
0.7 5.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.7 3.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.7 7.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.7 8.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 8.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7 20.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.7 19.0 GO:0097602 cullin family protein binding(GO:0097602)
0.7 7.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 4.7 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.6 17.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.6 2.6 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.6 44.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.6 7.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.6 1.8 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.6 27.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.6 16.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 8.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.6 8.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.6 4.0 GO:0004969 histamine receptor activity(GO:0004969)
0.6 25.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 9.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 2.7 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.5 5.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.5 1.5 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.5 16.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 18.4 GO:0005112 Notch binding(GO:0005112)
0.5 2.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.5 10.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.5 19.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.5 4.3 GO:0004568 chitinase activity(GO:0004568)
0.5 5.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 9.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.4 1.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.4 14.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 1.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.4 28.2 GO:0019894 kinesin binding(GO:0019894)
0.4 4.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 1.6 GO:0031433 telethonin binding(GO:0031433)
0.4 2.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 3.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 39.6 GO:0005518 collagen binding(GO:0005518)
0.4 9.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 14.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 3.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 4.8 GO:0046790 virion binding(GO:0046790)
0.4 1.8 GO:0070287 ferritin receptor activity(GO:0070287)
0.4 1.1 GO:0008127 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868) quercetin 2,3-dioxygenase activity(GO:0008127)
0.3 8.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 5.2 GO:0044548 S100 protein binding(GO:0044548)
0.3 7.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 3.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.3 9.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 6.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 1.3 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.3 1.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.3 3.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 8.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 9.1 GO:0030507 spectrin binding(GO:0030507)
0.3 7.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 6.5 GO:0009055 electron carrier activity(GO:0009055)
0.2 1.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 0.7 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.2 3.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 14.4 GO:0005158 insulin receptor binding(GO:0005158)
0.2 0.9 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 6.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.2 2.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 2.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 14.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 15.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 0.6 GO:0018169 ribosomal S6-glutamic acid ligase activity(GO:0018169)
0.2 7.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 71.3 GO:0003924 GTPase activity(GO:0003924)
0.2 17.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 7.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.5 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.6 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.2 8.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 6.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 4.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 21.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 1.3 GO:0015288 porin activity(GO:0015288)
0.2 3.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 4.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 4.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.0 GO:0030552 cAMP binding(GO:0030552)
0.2 5.3 GO:0070330 aromatase activity(GO:0070330)
0.2 2.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 6.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 5.8 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 1.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 10.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 9.6 GO:0051117 ATPase binding(GO:0051117)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 7.9 GO:0043621 protein self-association(GO:0043621)
0.1 15.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 52.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 9.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 8.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 5.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 2.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.2 GO:0097110 scaffold protein binding(GO:0097110)
0.1 6.3 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 3.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 5.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.5 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 1.2 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.7 17.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 33.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 45.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 15.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 37.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 12.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 10.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 7.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 14.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.3 14.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 13.6 PID IFNG PATHWAY IFN-gamma pathway
0.2 6.0 PID ARF 3PATHWAY Arf1 pathway
0.2 15.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 6.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 6.7 PID INSULIN PATHWAY Insulin Pathway
0.1 5.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 9.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 6.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 15.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.1 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.3 PID FGF PATHWAY FGF signaling pathway
0.1 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 13.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 40.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
2.9 71.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.7 63.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
2.3 41.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.9 40.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.7 119.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.5 20.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.1 24.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.1 37.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.1 17.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
1.0 16.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.9 21.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.9 18.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.9 11.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 43.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.8 19.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.8 27.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.8 26.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.8 11.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.8 9.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.7 21.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.7 7.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.7 15.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7 51.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.6 9.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 12.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.6 8.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 12.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 15.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.6 36.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 46.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.4 17.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.4 19.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 20.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 4.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 20.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 9.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 6.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.4 11.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 16.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4 4.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 20.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.4 7.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 9.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.4 7.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 12.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 17.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 7.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 15.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 19.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 5.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 32.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.3 8.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 4.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 6.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 7.1 REACTOME KINESINS Genes involved in Kinesins
0.2 11.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 3.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.2 18.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 2.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 6.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 3.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 4.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 12.8 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.1 8.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 5.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 17.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 4.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 8.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 4.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 7.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 5.5 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 6.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.9 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation