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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Ets1

Z-value: 2.86

Motif logo

Transcription factors associated with Ets1

Gene Symbol Gene ID Gene Info
ENSMUSG00000032035.17 Ets1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ets1mm39_v1_chr9_+_32607301_326074170.869.7e-22Click!

Activity profile of Ets1 motif

Sorted Z-values of Ets1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ets1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_126817475 45.14 ENSMUST00000106313.8
ENSMUST00000142356.3
septin 1
chr7_-_126817639 44.01 ENSMUST00000152267.8
ENSMUST00000106314.8
septin 1
chr19_-_4240984 27.34 ENSMUST00000045864.4
TBC1 domain family, member 10c
chr19_-_4241034 26.94 ENSMUST00000237495.2
TBC1 domain family, member 10c
chr7_-_126736979 25.74 ENSMUST00000049931.6
sialophorin
chr19_+_4204605 25.28 ENSMUST00000061086.9
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr1_-_133617824 25.01 ENSMUST00000189524.2
ENSMUST00000169295.8
lymphocyte transmembrane adaptor 1
chr17_+_34808772 23.88 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr17_+_34809132 23.36 ENSMUST00000173772.2
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr4_-_129467430 23.15 ENSMUST00000102596.8
lymphocyte protein tyrosine kinase
chr7_+_126895463 21.86 ENSMUST00000106306.9
ENSMUST00000120857.8
integrin alpha L
chr7_+_126895423 21.21 ENSMUST00000117762.8
integrin alpha L
chr11_-_79414542 21.10 ENSMUST00000179322.2
ecotropic viral integration site 2b
chr16_-_19801781 19.75 ENSMUST00000058839.10
kelch-like 6
chr7_+_24596806 19.66 ENSMUST00000003469.8
CD79A antigen (immunoglobulin-associated alpha)
chr4_-_63321591 18.81 ENSMUST00000035724.5
AT-hook transcription factor
chr15_+_84208915 18.73 ENSMUST00000023074.9
parvin, gamma
chr7_+_126895531 18.44 ENSMUST00000170971.8
integrin alpha L
chr3_+_106393348 18.16 ENSMUST00000183271.2
DENN/MADD domain containing 2D
chr1_+_171216480 17.76 ENSMUST00000056449.9
Rho GTPase activating protein 30
chr4_-_129452148 16.88 ENSMUST00000167288.8
ENSMUST00000134336.3
lymphocyte protein tyrosine kinase
chr4_-_129452180 16.53 ENSMUST00000067240.11
lymphocyte protein tyrosine kinase
chr3_-_89325594 16.06 ENSMUST00000029679.4
CDC28 protein kinase 1b
chr7_-_83304698 16.05 ENSMUST00000145610.8
interleukin 16
chr11_-_99045894 15.96 ENSMUST00000103134.4
chemokine (C-C motif) receptor 7
chr11_-_52173391 15.85 ENSMUST00000086844.10
transcription factor 7, T cell specific
chr11_-_106050724 15.72 ENSMUST00000064545.11
LIM domain containing 2
chr1_-_138102972 15.68 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr1_-_138103021 15.55 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr3_-_90603013 15.29 ENSMUST00000069960.12
ENSMUST00000117167.2
S100 calcium binding protein A9 (calgranulin B)
chr11_-_72441054 15.21 ENSMUST00000021154.7
spinster homolog 3
chr9_+_51124983 14.91 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chr9_-_44920899 14.76 ENSMUST00000102832.3
CD3 antigen, epsilon polypeptide
chr10_+_127157784 14.73 ENSMUST00000219511.2
Rho GTPase activating protein 9
chr2_-_118558852 14.71 ENSMUST00000102524.8
phospholipase C, beta 2
chr13_+_55517545 14.58 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr5_+_86219593 14.48 ENSMUST00000198435.5
ENSMUST00000031171.9
signal transducing adaptor family member 1
chr6_-_124715618 14.35 ENSMUST00000171549.9
protein tyrosine phosphatase, non-receptor type 6
chr5_-_140986312 14.07 ENSMUST00000085786.7
caspase recruitment domain family, member 11
chr6_-_124715560 13.83 ENSMUST00000004377.15
protein tyrosine phosphatase, non-receptor type 6
chr6_-_124715542 13.77 ENSMUST00000174265.2
protein tyrosine phosphatase, non-receptor type 6
chr19_+_41017714 13.72 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr5_-_134643805 13.30 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
linker for activation of T cells family, member 2
chr11_+_61017573 13.15 ENSMUST00000010286.8
ENSMUST00000146033.8
ENSMUST00000139422.8
tumor necrosis factor receptor superfamily, member 13b
chr11_+_33996920 13.14 ENSMUST00000052413.12
lymphocyte cytosolic protein 2
chr14_+_51366512 13.03 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr7_-_30119227 13.02 ENSMUST00000208740.2
ENSMUST00000075062.5
hematopoietic cell signal transducer
chr11_-_6470918 12.96 ENSMUST00000003459.4
myosin IG
chr8_-_84769170 12.94 ENSMUST00000005601.9
interleukin 27 receptor, alpha
chr11_+_103061905 12.77 ENSMUST00000042286.12
ENSMUST00000218163.2
formin-like 1
chrX_+_47235313 12.73 ENSMUST00000033427.7
SAM and SH3 domain containing 3
chr17_+_57586094 12.72 ENSMUST00000169220.9
ENSMUST00000005889.16
ENSMUST00000112870.5
vav 1 oncogene
chr11_+_33997114 12.56 ENSMUST00000109329.9
lymphocyte cytosolic protein 2
chr6_+_48715971 12.55 ENSMUST00000054368.7
ENSMUST00000140054.3
ENSMUST00000204168.2
ENSMUST00000204408.2
GTPase, IMAP family member 1
predicted gene, 28053
chr8_-_72175949 12.54 ENSMUST00000125092.2
FCH domain only 1
chr6_+_48661503 12.48 ENSMUST00000067506.14
ENSMUST00000119575.8
ENSMUST00000121957.8
ENSMUST00000090070.6
GTPase, IMAP family member 4
chr10_+_127159609 12.45 ENSMUST00000069548.7
Rho GTPase activating protein 9
chr2_+_22664094 12.41 ENSMUST00000014290.15
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_127159568 12.35 ENSMUST00000219026.2
Rho GTPase activating protein 9
chr7_+_24607042 12.32 ENSMUST00000151121.2
Rho guanine nucleotide exchange factor (GEF) 1
chr6_-_48685108 12.31 ENSMUST00000126422.3
ENSMUST00000119315.2
ENSMUST00000053661.7
GTPase, IMAP family member 6
chr14_-_32907023 12.29 ENSMUST00000130509.10
ENSMUST00000061753.15
WD repeat and FYVE domain containing 4
chr19_+_11495858 12.26 ENSMUST00000025580.10
membrane-spanning 4-domains, subfamily A, member 6B
chr15_-_102140331 12.21 ENSMUST00000230652.2
ENSMUST00000127014.3
ENSMUST00000001327.11
integrin beta 7
chr16_-_75706161 12.21 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chr1_+_34511793 12.03 ENSMUST00000188972.3
protein tyrosine phosphatase, non-receptor type 18
chr2_+_150412329 12.00 ENSMUST00000089200.3
cystatin F (leukocystatin)
chr1_+_130793406 11.96 ENSMUST00000038829.7
Fc fragment of IgM receptor
chr9_+_55997246 11.92 ENSMUST00000059206.8
proline-serine-threonine phosphatase-interacting protein 1
chrX_-_100311824 11.92 ENSMUST00000033664.14
interleukin 2 receptor, gamma chain
chr7_-_126391388 11.82 ENSMUST00000206570.2
protein phosphatase 4, catalytic subunit
chr4_+_130640436 11.75 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr11_+_3239868 11.70 ENSMUST00000094471.10
ENSMUST00000110043.8
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_88613967 11.70 ENSMUST00000098486.4
B cell leukemia/lymphoma 2 related protein A1d
chr11_-_70128678 11.55 ENSMUST00000108575.9
RIKEN cDNA 0610010K14 gene
chr1_+_61017057 11.51 ENSMUST00000027162.12
ENSMUST00000102827.4
inducible T cell co-stimulator
chr17_+_34311314 11.49 ENSMUST00000025192.8
histocompatibility 2, O region alpha locus
chr12_-_32258604 11.43 ENSMUST00000053215.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr11_+_72851989 11.41 ENSMUST00000163326.8
ENSMUST00000108485.9
ENSMUST00000021142.8
ENSMUST00000108486.8
ENSMUST00000108484.8
ATPase, Ca++ transporting, ubiquitous
chr7_+_28140352 11.36 ENSMUST00000078845.13
glia maturation factor, gamma
chr9_-_57743989 11.24 ENSMUST00000164010.8
ENSMUST00000171444.8
ENSMUST00000098686.4
AT rich interactive domain 3B (BRIGHT-like)
chr12_-_32258331 11.23 ENSMUST00000220366.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr15_-_66432938 11.20 ENSMUST00000048372.7
transmembrane protein 71
chr19_-_11243530 11.09 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr18_+_50164043 11.08 ENSMUST00000145726.2
ENSMUST00000128377.2
tumor necrosis factor, alpha-induced protein 8
chrX_-_7956682 11.07 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr6_+_48661477 11.05 ENSMUST00000118802.8
GTPase, IMAP family member 4
chr16_-_3794404 11.01 ENSMUST00000180200.8
NLR family, CARD domain containing 3
chr3_+_87754057 10.90 ENSMUST00000107581.9
SH2 domain containing 2A
chr2_+_24276616 10.90 ENSMUST00000166388.2
pleckstrin and Sec7 domain containing 4
chr3_+_87754310 10.82 ENSMUST00000029709.7
SH2 domain containing 2A
chr2_-_118558825 10.82 ENSMUST00000159756.2
phospholipase C, beta 2
chr12_-_32258469 10.79 ENSMUST00000085469.6
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr1_-_131127825 10.74 ENSMUST00000068564.15
Ras association (RalGDS/AF-6) domain family member 5
chr9_-_20864096 10.71 ENSMUST00000004202.17
DNA methyltransferase (cytosine-5) 1
chr3_+_90511068 10.70 ENSMUST00000001046.7
S100 calcium binding protein A4
chr15_-_66684442 10.66 ENSMUST00000100572.10
src-like adaptor
chrX_+_106299484 10.65 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr11_-_70128712 10.56 ENSMUST00000108577.8
ENSMUST00000108579.8
ENSMUST00000021181.13
ENSMUST00000108578.9
ENSMUST00000102569.10
RIKEN cDNA 0610010K14 gene
chr7_+_28488380 10.52 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr7_-_44180700 10.49 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr12_-_114104740 10.48 ENSMUST00000103473.2
immunoglobulin heavy variable V9-3
chr11_+_117673107 10.48 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr2_-_31973795 10.48 ENSMUST00000056406.7
family with sequence similarity 78, member A
chr1_+_165616250 10.36 ENSMUST00000161971.8
ENSMUST00000187313.7
ENSMUST00000178336.8
ENSMUST00000005907.12
ENSMUST00000027849.11
CD247 antigen
chr15_+_103362195 10.32 ENSMUST00000047405.9
NCK associated protein 1 like
chr14_-_70412804 10.27 ENSMUST00000143393.2
PDZ and LIM domain 2
chr9_-_22042930 10.18 ENSMUST00000213815.2
acid phosphatase 5, tartrate resistant
chr15_-_9529898 10.11 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr3_+_130904000 10.10 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr11_-_115968373 10.09 ENSMUST00000174822.8
unc-13 homolog D
chr2_+_90927053 10.01 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr19_+_12775938 9.93 ENSMUST00000025601.8
leupaxin
chr6_-_87473260 9.93 ENSMUST00000101197.9
Rho GTPase activating protein 25
chr7_+_119393210 9.85 ENSMUST00000033218.15
ENSMUST00000106520.9
RNA exonuclease 5
chr1_+_152683627 9.82 ENSMUST00000027754.7
neutrophil cytosolic factor 2
chr17_-_52133594 9.81 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr7_-_44888532 9.79 ENSMUST00000033063.15
CD37 antigen
chr8_-_89362745 9.71 ENSMUST00000034087.9
sorting nexin 20
chr17_+_47816042 9.63 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr7_+_16576978 9.61 ENSMUST00000086104.6
protein kinase D2
chr7_-_101899294 9.57 ENSMUST00000106923.2
ENSMUST00000098230.11
ras homolog family member G
chr4_-_122779698 9.56 ENSMUST00000069533.12
CAP, adenylate cyclase-associated protein 1 (yeast)
chr2_+_43638814 9.55 ENSMUST00000112824.8
ENSMUST00000055776.8
Rho GTPase activating protein 15
chr5_-_65248927 9.53 ENSMUST00000043352.8
transmembrane protein 156
chr9_+_88838953 9.50 ENSMUST00000098485.4
B cell leukemia/lymphoma 2 related protein A1a
chr7_-_44888220 9.42 ENSMUST00000210372.2
ENSMUST00000209779.2
ENSMUST00000098461.10
ENSMUST00000211373.2
CD37 antigen
chr7_+_28140450 9.33 ENSMUST00000135686.2
glia maturation factor, gamma
chr7_+_16576821 9.29 ENSMUST00000168093.9
protein kinase D2
chr17_+_47815968 9.21 ENSMUST00000182129.8
ENSMUST00000171031.8
cyclin D3
chr17_-_34109513 9.18 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr17_+_33774681 9.17 ENSMUST00000087605.13
ENSMUST00000174695.2
myosin IF
chr1_+_85577709 9.17 ENSMUST00000155094.8
ENSMUST00000054279.15
ENSMUST00000147552.8
ENSMUST00000153574.8
ENSMUST00000150967.8
nuclear antigen Sp100
chr7_+_24069680 9.17 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_152689881 9.16 ENSMUST00000164120.8
ENSMUST00000178997.8
ENSMUST00000109816.8
TPX2, microtubule-associated
chr1_+_85577766 9.15 ENSMUST00000066427.11
nuclear antigen Sp100
chr1_+_135060431 9.15 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr11_+_101333238 9.14 ENSMUST00000107249.8
ribosomal protein L27
chr10_+_41352310 8.99 ENSMUST00000019967.16
ENSMUST00000119962.8
ENSMUST00000099934.11
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr11_+_117673198 8.97 ENSMUST00000117781.8
transmembrane channel-like gene family 8
chr17_+_47816074 8.93 ENSMUST00000183177.8
ENSMUST00000182848.8
cyclin D3
chr7_+_126184108 8.93 ENSMUST00000039522.8
apolipoprotein B receptor
chr4_+_130640611 8.91 ENSMUST00000156225.8
ENSMUST00000156742.8
lysosomal-associated protein transmembrane 5
chr7_-_121732067 8.81 ENSMUST00000106469.8
ENSMUST00000063587.13
ENSMUST00000106468.7
ENSMUST00000098068.10
partner and localizer of BRCA2
chr7_+_100145192 8.80 ENSMUST00000133044.3
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_101333115 8.79 ENSMUST00000077856.13
ribosomal protein L27
chr8_+_106412905 8.79 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr1_-_80643024 8.78 ENSMUST00000187774.7
dedicator of cytokinesis 10
chr1_-_80642969 8.78 ENSMUST00000190983.7
ENSMUST00000191449.2
dedicator of cytokinesis 10
chr16_-_48592319 8.74 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr7_-_44888465 8.73 ENSMUST00000210078.2
CD37 antigen
chr16_+_36755338 8.73 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr7_+_24602337 8.70 ENSMUST00000117796.8
ENSMUST00000047873.16
ENSMUST00000098683.11
ENSMUST00000206508.2
ENSMUST00000206028.2
Rho guanine nucleotide exchange factor (GEF) 1
chr6_-_129449739 8.69 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr1_-_54965470 8.66 ENSMUST00000179030.8
ENSMUST00000044359.16
ankyrin repeat domain 44
chr5_+_97145533 8.66 ENSMUST00000112974.6
ENSMUST00000035635.10
BMP2 inducible kinase
chr10_+_79722081 8.65 ENSMUST00000046091.7
elastase, neutrophil expressed
chrX_+_99669343 8.64 ENSMUST00000048962.4
kinesin family member 4
chr11_-_16958647 8.61 ENSMUST00000102881.10
pleckstrin
chr11_+_32483290 8.53 ENSMUST00000102821.4
serine/threonine kinase 10
chr11_+_96355413 8.53 ENSMUST00000103154.11
ENSMUST00000100521.10
ENSMUST00000100519.11
src family associated phosphoprotein 1
chr6_-_56681657 8.53 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_48592372 8.49 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr8_-_123159639 8.43 ENSMUST00000212600.2
cytochrome b-245, alpha polypeptide
chr9_-_20556031 8.41 ENSMUST00000148631.8
ENSMUST00000131128.2
ENSMUST00000151861.9
ENSMUST00000131343.8
ENSMUST00000086458.10
F-box and leucine-rich repeat protein 12
chr7_-_128019874 8.40 ENSMUST00000145739.3
ENSMUST00000033133.12
regulator of G-protein signalling 10
chr16_+_19578981 8.35 ENSMUST00000079780.10
ENSMUST00000164397.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr11_+_96355441 8.27 ENSMUST00000071510.14
ENSMUST00000107662.9
src family associated phosphoprotein 1
chr9_+_56325893 8.26 ENSMUST00000034879.5
ENSMUST00000215269.2
high mobility group 20A
chr15_+_78481247 8.24 ENSMUST00000043069.6
ENSMUST00000231180.2
ENSMUST00000229796.2
ENSMUST00000229295.2
cytohesin 4
chr9_+_21437440 8.24 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chrX_+_56257374 8.23 ENSMUST00000033466.2
CD40 ligand
chr9_+_56326089 8.14 ENSMUST00000213242.2
ENSMUST00000214771.2
ENSMUST00000217518.2
ENSMUST00000214869.2
high mobility group 20A
chr1_+_171668173 8.12 ENSMUST00000136479.8
CD84 antigen
chr17_+_47815998 8.08 ENSMUST00000183210.2
cyclin D3
chr1_+_135060994 8.06 ENSMUST00000167080.3
protein tyrosine phosphatase, non-receptor type 7
chr9_+_89081262 8.01 ENSMUST00000068569.5
B cell leukemia/lymphoma 2 related protein A1b
chr17_-_52140305 8.00 ENSMUST00000133574.8
special AT-rich sequence binding protein 1
chr13_-_17979675 8.00 ENSMUST00000223490.2
cyclin-dependent kinase 13
chr4_-_122779742 7.99 ENSMUST00000128485.2
CAP, adenylate cyclase-associated protein 1 (yeast)
chr10_-_93146825 7.99 ENSMUST00000151153.2
ELK3, member of ETS oncogene family
chr2_-_130021229 7.96 ENSMUST00000103199.9
small nuclear ribonucleoprotein B
chr5_+_149121458 7.94 ENSMUST00000122160.8
ENSMUST00000100410.10
ENSMUST00000119685.8
ubiquitin specific peptidase like 1
chr17_+_35460722 7.89 ENSMUST00000068056.12
ENSMUST00000174757.8
ENSMUST00000173731.8
DEAD box helicase 39b
chr17_-_50401305 7.87 ENSMUST00000113195.8
raftlin lipid raft linker 1
chr14_-_122153185 7.85 ENSMUST00000055475.9
G protein-coupled receptor 18
chr3_-_106697459 7.85 ENSMUST00000038845.10
CD53 antigen
chr11_-_46203047 7.83 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr8_+_4375212 7.83 ENSMUST00000127460.8
ENSMUST00000136191.8
chemokine (C-C motif) ligand 25
chr7_+_43086432 7.81 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr14_-_31216949 7.76 ENSMUST00000228181.2
ENSMUST00000227777.2
ENSMUST00000227595.2
ENSMUST00000228727.2
ENSMUST00000055303.5
methyltransferase like 6
chr12_-_114263874 7.74 ENSMUST00000103482.2
ENSMUST00000194159.2
immunoglobulin heavy variable 9-4
chr7_+_28682253 7.74 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr5_-_65248962 7.73 ENSMUST00000212080.2
transmembrane protein 156
chr9_-_57552392 7.73 ENSMUST00000216934.2
c-src tyrosine kinase
chr2_+_152689913 7.72 ENSMUST00000028969.9
TPX2, microtubule-associated
chr17_+_47816137 7.69 ENSMUST00000182935.8
ENSMUST00000182506.8
cyclin D3
chr11_+_68322945 7.67 ENSMUST00000021283.8
phosphoinositide-3-kinase regulatory subunit 5
chr9_-_57552844 7.66 ENSMUST00000216979.2
ENSMUST00000034863.8
c-src tyrosine kinase
chr2_-_26250886 7.65 ENSMUST00000028294.7
caspase recruitment domain family, member 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.7 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
8.2 73.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
8.0 16.0 GO:2000520 regulation of immunological synapse formation(GO:2000520)
7.8 31.2 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
6.9 20.7 GO:0071846 actin filament debranching(GO:0071846)
5.8 52.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
5.6 16.9 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
5.3 42.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
5.1 66.9 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
5.1 15.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
4.2 33.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
3.9 3.9 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
3.8 11.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
3.8 19.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
3.7 11.1 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
3.7 11.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
3.6 25.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.5 14.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
3.4 20.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
3.3 9.9 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
3.3 3.3 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
3.2 13.0 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
3.2 6.4 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
3.2 6.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
3.2 47.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
3.1 27.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
3.1 15.5 GO:0030576 Cajal body organization(GO:0030576)
3.1 15.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
3.0 9.0 GO:0019417 sulfur oxidation(GO:0019417)
2.9 8.8 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
2.9 28.8 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
2.9 8.6 GO:0060305 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
2.8 11.4 GO:0007113 endomitotic cell cycle(GO:0007113)
2.8 28.3 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
2.8 8.4 GO:0014805 smooth muscle adaptation(GO:0014805)
2.8 5.6 GO:0090135 actin filament branching(GO:0090135)
2.7 8.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
2.7 10.7 GO:0090309 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
2.6 7.9 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
2.4 7.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
2.4 9.7 GO:0017126 nucleologenesis(GO:0017126)
2.4 7.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
2.4 11.9 GO:1901355 response to rapamycin(GO:1901355)
2.4 9.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.4 4.7 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
2.3 44.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.3 9.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
2.3 6.8 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
2.3 9.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
2.2 55.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
2.2 6.6 GO:0071163 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.1 17.1 GO:0002432 granuloma formation(GO:0002432)
2.1 17.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.1 6.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
2.1 6.2 GO:1904093 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
2.0 10.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
2.0 12.0 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
2.0 4.0 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
2.0 11.9 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
1.9 9.7 GO:0002352 B cell negative selection(GO:0002352)
1.9 9.6 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
1.9 15.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.9 7.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
1.8 23.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.8 12.3 GO:2000002 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
1.7 5.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.7 3.4 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.7 6.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.7 5.0 GO:1904826 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
1.7 8.4 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
1.7 8.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.6 6.5 GO:0046898 response to cycloheximide(GO:0046898)
1.6 12.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
1.6 9.6 GO:0006742 NADP catabolic process(GO:0006742)
1.6 17.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.6 4.7 GO:0045212 neurotransmitter receptor biosynthetic process(GO:0045212)
1.5 10.7 GO:0060057 negative regulation of translation in response to stress(GO:0032055) negative regulation of interleukin-1 beta secretion(GO:0050713) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.5 4.5 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
1.5 28.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.5 4.5 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
1.5 22.1 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
1.5 7.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.5 5.8 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.5 2.9 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
1.4 12.9 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
1.4 5.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
1.4 7.1 GO:0042631 cellular response to water deprivation(GO:0042631)
1.4 2.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.4 6.9 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.3 6.7 GO:0009597 detection of virus(GO:0009597)
1.3 5.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.3 1.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.3 5.2 GO:0019323 pentose catabolic process(GO:0019323)
1.3 12.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.3 5.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.2 13.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
1.2 12.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
1.2 3.7 GO:0006740 NADPH regeneration(GO:0006740)
1.2 4.9 GO:0000390 spliceosomal complex disassembly(GO:0000390)
1.2 2.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.2 6.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.2 4.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.2 6.0 GO:0002507 tolerance induction(GO:0002507)
1.2 4.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.2 7.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
1.2 19.1 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
1.2 19.1 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
1.2 3.6 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
1.2 8.3 GO:0070889 platelet alpha granule organization(GO:0070889)
1.2 3.5 GO:0006407 rRNA export from nucleus(GO:0006407)
1.2 5.8 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
1.2 13.8 GO:0051014 actin filament severing(GO:0051014)
1.1 25.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.1 5.7 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.1 2.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
1.1 6.6 GO:0040010 positive regulation of growth rate(GO:0040010)
1.1 14.3 GO:0002517 T cell tolerance induction(GO:0002517)
1.1 6.6 GO:0009826 unidimensional cell growth(GO:0009826)
1.1 8.8 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.1 6.5 GO:0045076 regulation of interleukin-2 biosynthetic process(GO:0045076)
1.1 5.4 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.1 4.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.1 1.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.0 3.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.0 4.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
1.0 20.7 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
1.0 16.5 GO:0035855 megakaryocyte development(GO:0035855)
1.0 6.1 GO:1990839 response to endothelin(GO:1990839)
1.0 3.0 GO:0043366 beta selection(GO:0043366)
1.0 29.4 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
1.0 2.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
1.0 83.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
1.0 28.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
1.0 3.9 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
1.0 6.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.0 4.8 GO:0002159 desmosome assembly(GO:0002159)
1.0 8.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.0 14.4 GO:0042989 sequestering of actin monomers(GO:0042989)
1.0 4.8 GO:0002418 immune response to tumor cell(GO:0002418)
0.9 3.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.9 5.6 GO:0097531 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.9 2.8 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.9 0.9 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.9 7.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.9 3.7 GO:1902276 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
0.9 3.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.9 3.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.9 17.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.9 4.5 GO:0048478 replication fork protection(GO:0048478)
0.9 18.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.9 2.7 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.9 6.3 GO:0016266 O-glycan processing(GO:0016266)
0.9 2.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.9 3.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.9 6.9 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.9 4.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.9 6.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 6.0 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532)
0.9 2.6 GO:0035874 amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.9 6.8 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.9 4.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.8 2.5 GO:0042262 DNA protection(GO:0042262) dATP catabolic process(GO:0046061)
0.8 2.5 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.8 3.2 GO:0032079 glucosylceramide catabolic process(GO:0006680) positive regulation of endodeoxyribonuclease activity(GO:0032079) positive regulation of phospholipid catabolic process(GO:0060697)
0.8 2.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.8 2.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.8 2.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.8 7.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8 2.3 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.8 2.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.8 2.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 4.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.8 15.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.8 3.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.8 3.0 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.8 12.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.8 26.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.7 4.5 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.7 5.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.7 2.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.7 16.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 2.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.7 10.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.7 1.5 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.7 2.2 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.7 2.9 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.7 2.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.7 17.1 GO:0002467 germinal center formation(GO:0002467)
0.7 1.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.7 4.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.7 7.0 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.7 4.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.7 9.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.7 5.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.7 1.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.7 1.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.7 5.5 GO:0014029 neural crest formation(GO:0014029)
0.7 11.5 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.7 25.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7 2.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.7 1.3 GO:1902566 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.7 2.0 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.6 27.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.6 17.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.6 7.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.6 7.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.6 8.8 GO:0080009 mRNA methylation(GO:0080009)
0.6 1.9 GO:0036245 cellular response to menadione(GO:0036245)
0.6 4.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.6 13.8 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6 1.9 GO:0061511 centriole elongation(GO:0061511)
0.6 3.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.6 1.9 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.6 5.6 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.6 2.4 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.6 1.8 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.6 2.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.6 8.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.6 4.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.6 2.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.6 3.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.6 2.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.6 5.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.6 13.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.6 1.7 GO:0032053 ciliary basal body organization(GO:0032053)
0.6 5.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.6 1.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.6 5.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.6 2.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.6 5.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.6 5.0 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.6 5.0 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.6 1.7 GO:0006059 hexitol metabolic process(GO:0006059) glycolytic process from galactose(GO:0061623)
0.5 2.2 GO:0000022 mitotic spindle elongation(GO:0000022)
0.5 8.5 GO:0043248 proteasome assembly(GO:0043248)
0.5 3.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.5 4.7 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.5 6.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.5 3.1 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.5 7.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 1.5 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.5 2.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.5 3.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 3.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.5 5.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.5 1.5 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.5 2.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.5 2.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.5 2.4 GO:1990743 protein sialylation(GO:1990743)
0.5 8.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.5 14.5 GO:0033198 response to ATP(GO:0033198)
0.5 6.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 3.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 6.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.5 1.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.5 6.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.5 12.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.5 1.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.5 3.7 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.5 3.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.5 2.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.5 1.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.5 1.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 1.4 GO:0046038 GMP catabolic process(GO:0046038)
0.5 16.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 14.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 3.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 3.1 GO:0035633 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.4 2.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 10.6 GO:0043029 T cell homeostasis(GO:0043029)
0.4 2.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.4 2.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.4 2.6 GO:0006379 mRNA cleavage(GO:0006379)
0.4 3.9 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.4 3.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.4 4.8 GO:0015074 DNA integration(GO:0015074)
0.4 4.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.4 3.8 GO:0006265 DNA topological change(GO:0006265)
0.4 7.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4 3.8 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.4 2.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 12.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 6.7 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.4 59.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.4 15.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.4 6.5 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.4 9.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.4 11.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.4 5.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.4 1.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 4.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.4 0.8 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.4 2.7 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.4 1.6 GO:0015786 UDP-glucose transport(GO:0015786)
0.4 10.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.4 17.1 GO:0006284 base-excision repair(GO:0006284)
0.4 1.2 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.4 6.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.4 8.8 GO:0042113 B cell activation(GO:0042113)
0.4 5.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.4 9.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.4 6.4 GO:0045730 respiratory burst(GO:0045730)
0.4 0.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.4 5.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.4 2.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 1.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 2.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 9.9 GO:0035411 catenin import into nucleus(GO:0035411)
0.4 2.9 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.4 16.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.4 2.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.4 6.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.4 2.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 5.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.4 13.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.4 3.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 4.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.4 1.1 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.4 3.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.4 0.7 GO:1902583 intracellular transport of virus(GO:0075733) regulation of intracellular transport of viral material(GO:1901252) multi-organism intracellular transport(GO:1902583)
0.3 3.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 1.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.3 3.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 1.7 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 10.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.3 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 3.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 3.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 1.7 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.3 9.1 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.3 10.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.3 1.0 GO:0051030 snRNA transport(GO:0051030)
0.3 11.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.6 GO:0046075 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.3 2.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.3 6.0 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.3 1.3 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.3 12.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 3.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.3 2.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 11.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 1.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3 0.9 GO:0051542 elastin biosynthetic process(GO:0051542)
0.3 2.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 8.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.3 2.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.3 0.3 GO:0097325 regulation of collagen catabolic process(GO:0010710) melanocyte proliferation(GO:0097325)
0.3 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.3 1.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 11.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.3 0.9 GO:0034970 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) histone H3-R2 methylation(GO:0034970)
0.3 2.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 5.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.3 3.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 1.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 13.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 12.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 1.4 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 0.5 GO:0050755 chemokine metabolic process(GO:0050755)
0.3 7.0 GO:0006491 N-glycan processing(GO:0006491)
0.3 1.6 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3 8.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 1.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 2.9 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.3 2.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 3.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 4.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 0.8 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.3 1.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.3 3.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 1.5 GO:0051031 tRNA transport(GO:0051031)
0.2 2.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 11.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.2 1.5 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.2 2.9 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 18.8 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.2 3.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.2 1.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 1.4 GO:0007000 nucleolus organization(GO:0007000)
0.2 0.7 GO:0030035 microspike assembly(GO:0030035)
0.2 1.6 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 1.6 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 21.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 7.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 4.6 GO:0006301 postreplication repair(GO:0006301)
0.2 16.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 3.8 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.2 0.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 13.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 2.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.2 3.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 3.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 1.1 GO:2000584 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 2.1 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 5.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 1.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 3.4 GO:0034508 centromere complex assembly(GO:0034508)
0.2 2.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 2.9 GO:0001782 B cell homeostasis(GO:0001782)
0.2 2.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.7 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 2.6 GO:0030225 macrophage differentiation(GO:0030225)
0.2 2.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 0.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 6.1 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.2 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 13.3 GO:0030183 B cell differentiation(GO:0030183)
0.2 2.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.2 GO:0030578 PML body organization(GO:0030578)
0.2 14.1 GO:0030217 T cell differentiation(GO:0030217)
0.2 2.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 5.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.2 0.7 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 3.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 1.0 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.2 1.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 1.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.2 6.1 GO:0070527 platelet aggregation(GO:0070527)
0.2 23.9 GO:0002377 immunoglobulin production(GO:0002377)
0.2 7.7 GO:0006414 translational elongation(GO:0006414)
0.2 7.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 4.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.2 6.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 0.8 GO:0009624 response to nematode(GO:0009624)
0.2 3.6 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 1.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 7.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 5.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 3.0 GO:0030168 platelet activation(GO:0030168)
0.1 28.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 3.2 GO:0070918 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1 1.1 GO:1903209 positive regulation of cellular response to oxidative stress(GO:1900409) positive regulation of oxidative stress-induced cell death(GO:1903209)
0.1 1.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 2.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 2.6 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.1 2.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.9 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 2.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 19.1 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 4.2 GO:0031424 keratinization(GO:0031424)
0.1 0.8 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 3.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 3.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 4.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 7.3 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 12.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 3.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.6 GO:1901985 positive regulation of protein acetylation(GO:1901985)
0.1 3.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 36.0 GO:0008380 RNA splicing(GO:0008380)
0.1 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.1 2.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 3.0 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 2.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 1.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.1 10.6 GO:0000910 cytokinesis(GO:0000910)
0.1 1.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.7 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
0.1 1.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.1 4.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.6 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 2.1 GO:0044804 nucleophagy(GO:0044804)
0.1 1.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 2.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 0.3 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.1 1.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 5.2 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1 0.6 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.1 0.4 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1 2.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.1 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.1 3.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 3.5 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.1 5.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 3.1 GO:0060425 lung morphogenesis(GO:0060425)
0.1 1.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 2.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.7 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.7 GO:0030033 microvillus assembly(GO:0030033)
0.1 3.6 GO:0048278 vesicle docking(GO:0048278)
0.1 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 2.2 GO:0016925 protein sumoylation(GO:0016925)
0.1 1.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.2 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.1 1.7 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.1 0.3 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 1.6 GO:0045576 mast cell activation(GO:0045576)
0.1 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.9 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.4 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 0.6 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.8 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.1 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.5 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.6 GO:0006541 glutamine metabolic process(GO:0006541)
0.1 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 2.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.1 4.4 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 4.2 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 6.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.8 GO:0097484 dendrite extension(GO:0097484)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.0 1.0 GO:0034644 cellular response to UV(GO:0034644)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.4 GO:0021684 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 1.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 1.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 1.9 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.0 GO:0001656 metanephros development(GO:0001656)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:1905208 negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 1.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0006903 vesicle targeting(GO:0006903)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 61.5 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
8.6 25.7 GO:0036398 TCR signalosome(GO:0036398)
8.1 40.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
6.4 25.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
5.9 70.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
3.6 71.2 GO:0042101 T cell receptor complex(GO:0042101)
3.5 24.6 GO:0019815 B cell receptor complex(GO:0019815)
3.0 42.7 GO:0016589 NURF complex(GO:0016589)
2.9 20.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
2.9 14.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
2.7 8.1 GO:1990031 pinceau fiber(GO:1990031)
2.7 8.0 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
2.6 13.0 GO:0000799 nuclear condensin complex(GO:0000799)
2.4 9.6 GO:0008623 CHRAC(GO:0008623)
2.4 12.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
2.2 6.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.2 34.5 GO:0043020 NADPH oxidase complex(GO:0043020)
2.1 107.4 GO:0001772 immunological synapse(GO:0001772)
2.1 16.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
2.0 6.1 GO:0070435 Shc-EGFR complex(GO:0070435)
2.0 20.1 GO:0033093 Weibel-Palade body(GO:0033093)
2.0 11.9 GO:0005826 actomyosin contractile ring(GO:0005826)
2.0 25.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.6 20.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.5 10.8 GO:0072487 MSL complex(GO:0072487)
1.5 10.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.5 51.7 GO:0031527 filopodium membrane(GO:0031527)
1.4 4.2 GO:0034455 t-UTP complex(GO:0034455)
1.3 6.6 GO:0017177 glucosidase II complex(GO:0017177)
1.3 8.8 GO:0036396 MIS complex(GO:0036396)
1.2 10.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 8.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.2 3.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.2 15.7 GO:0005818 aster(GO:0005818)
1.2 16.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.1 12.6 GO:0005687 U4 snRNP(GO:0005687)
1.1 5.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
1.1 5.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.1 10.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 75.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.0 6.2 GO:0033553 rDNA heterochromatin(GO:0033553)
1.0 4.8 GO:0005914 spot adherens junction(GO:0005914)
1.0 3.9 GO:0042585 germinal vesicle(GO:0042585)
1.0 11.5 GO:0042613 MHC class II protein complex(GO:0042613)
1.0 4.8 GO:0044194 cytolytic granule(GO:0044194)
0.9 7.5 GO:0070847 core mediator complex(GO:0070847)
0.9 12.8 GO:0016600 flotillin complex(GO:0016600)
0.9 75.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 8.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.9 8.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.9 6.0 GO:0089701 U2AF(GO:0089701)
0.8 10.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.8 10.0 GO:0000801 central element(GO:0000801)
0.8 5.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.8 6.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.8 2.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.8 5.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.8 16.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.8 4.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.8 5.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 3.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.8 2.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.8 5.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.7 5.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.7 11.0 GO:0032433 filopodium tip(GO:0032433)
0.7 2.2 GO:0000814 ESCRT II complex(GO:0000814)
0.7 7.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.7 11.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.7 38.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.6 1.9 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.6 5.7 GO:0071141 SMAD protein complex(GO:0071141)
0.6 9.4 GO:0042555 MCM complex(GO:0042555)
0.6 3.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.6 4.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.6 4.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 5.3 GO:0010369 chromocenter(GO:0010369)
0.6 2.9 GO:0031298 replication fork protection complex(GO:0031298)
0.6 3.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.6 5.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5 1.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.5 1.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.5 7.9 GO:0031209 SCAR complex(GO:0031209)
0.5 7.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.5 13.8 GO:0001891 phagocytic cup(GO:0001891)
0.5 2.0 GO:0036019 endolysosome(GO:0036019)
0.5 2.0 GO:0032021 NELF complex(GO:0032021)
0.5 4.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 1.5 GO:0055087 Ski complex(GO:0055087)
0.5 4.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 10.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.5 14.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.5 30.2 GO:0000791 euchromatin(GO:0000791)
0.5 1.4 GO:1902560 GMP reductase complex(GO:1902560)
0.5 17.3 GO:0032040 small-subunit processome(GO:0032040)
0.5 7.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 8.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 2.6 GO:1990393 3M complex(GO:1990393)
0.4 12.6 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 2.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 29.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.4 10.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 4.7 GO:0061700 GATOR2 complex(GO:0061700)
0.4 5.1 GO:0008278 cohesin complex(GO:0008278)
0.4 52.8 GO:0016605 PML body(GO:0016605)
0.4 3.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.4 2.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 4.5 GO:0070578 RISC-loading complex(GO:0070578)
0.4 4.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 3.6 GO:0070552 BRISC complex(GO:0070552)
0.4 4.0 GO:0061574 ASAP complex(GO:0061574)
0.4 42.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.4 2.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.4 2.0 GO:0001940 male pronucleus(GO:0001940)
0.4 11.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.4 13.9 GO:0008305 integrin complex(GO:0008305)
0.4 14.9 GO:0035371 microtubule plus-end(GO:0035371)
0.4 4.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 16.1 GO:0015030 Cajal body(GO:0015030)
0.4 7.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.4 1.1 GO:0034657 GID complex(GO:0034657)
0.3 1.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 180.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 4.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 1.7 GO:0000125 PCAF complex(GO:0000125)
0.3 3.0 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.3 2.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 1.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 3.1 GO:0000322 storage vacuole(GO:0000322)
0.3 1.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 28.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 1.5 GO:0000346 transcription export complex(GO:0000346)
0.3 1.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 2.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 4.5 GO:0045120 pronucleus(GO:0045120)
0.3 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 3.1 GO:0000815 ESCRT III complex(GO:0000815)
0.3 6.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 3.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 11.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 3.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 11.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 2.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 1.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 25.0 GO:0005795 Golgi stack(GO:0005795)
0.2 15.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 4.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.0 GO:0043293 apoptosome(GO:0043293)
0.2 1.6 GO:0097422 tubular endosome(GO:0097422)
0.2 3.9 GO:0030686 90S preribosome(GO:0030686)
0.2 41.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 10.3 GO:0045171 intercellular bridge(GO:0045171)
0.2 4.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.4 GO:0043596 nuclear replication fork(GO:0043596)
0.2 1.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 0.7 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 0.7 GO:0044393 microspike(GO:0044393)
0.2 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 7.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 5.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 60.2 GO:0016607 nuclear speck(GO:0016607)
0.2 16.8 GO:0032587 ruffle membrane(GO:0032587)
0.2 35.4 GO:0031965 nuclear membrane(GO:0031965)
0.2 4.8 GO:0099738 cell cortex region(GO:0099738)
0.2 11.7 GO:0001726 ruffle(GO:0001726)
0.2 3.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.2 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:0071986 Ragulator complex(GO:0071986)
0.1 4.7 GO:0016460 myosin II complex(GO:0016460)
0.1 2.4 GO:0005771 multivesicular body(GO:0005771)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 5.7 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 4.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 14.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 16.2 GO:0001650 fibrillar center(GO:0001650)
0.1 11.5 GO:0000922 spindle pole(GO:0000922)
0.1 8.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 13.7 GO:0072562 blood microparticle(GO:0072562)
0.1 11.7 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 16.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 8.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 3.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0022624 proteasome accessory complex(GO:0022624)
0.1 22.3 GO:0000790 nuclear chromatin(GO:0000790)
0.1 4.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 13.9 GO:0000793 condensed chromosome(GO:0000793)
0.1 5.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.3 GO:0042588 zymogen granule(GO:0042588)
0.1 1.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 4.3 GO:0005819 spindle(GO:0005819)
0.1 1.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 7.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 4.2 GO:0005694 chromosome(GO:0005694)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0005767 secondary lysosome(GO:0005767) autolysosome(GO:0044754)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 61.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
11.3 56.6 GO:0042610 CD8 receptor binding(GO:0042610)
6.2 18.7 GO:0070138 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
5.2 15.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
4.8 14.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
4.1 20.3 GO:0019976 interleukin-2 binding(GO:0019976)
4.0 28.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.3 9.9 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
3.0 38.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.8 11.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.7 8.2 GO:0005174 CD40 receptor binding(GO:0005174)
2.7 16.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.6 26.0 GO:0050786 RAGE receptor binding(GO:0050786)
2.6 10.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
2.6 10.3 GO:1990932 5.8S rRNA binding(GO:1990932)
2.5 33.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
2.5 15.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
2.4 11.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.2 28.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.2 8.7 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
2.1 6.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
2.0 6.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
2.0 8.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
2.0 21.7 GO:0050700 CARD domain binding(GO:0050700)
2.0 7.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.9 7.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.9 5.7 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
1.9 5.7 GO:0035500 MH2 domain binding(GO:0035500)
1.9 16.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.9 14.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.9 48.4 GO:0051400 BH domain binding(GO:0051400)
1.8 16.1 GO:0042609 CD4 receptor binding(GO:0042609)
1.7 8.6 GO:0030621 U4 snRNA binding(GO:0030621)
1.7 5.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.6 6.5 GO:0005136 interleukin-4 receptor binding(GO:0005136) ceramide binding(GO:0097001)
1.6 4.8 GO:0036461 BLOC-2 complex binding(GO:0036461)
1.6 6.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.5 12.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.5 21.1 GO:0019957 C-C chemokine binding(GO:0019957)
1.5 6.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.5 4.5 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
1.5 8.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.5 18.9 GO:0001055 RNA polymerase II activity(GO:0001055)
1.5 4.4 GO:0035375 zymogen binding(GO:0035375)
1.4 10.1 GO:0030284 estrogen receptor activity(GO:0030284)
1.4 12.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 5.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
1.3 3.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.3 5.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.3 5.2 GO:0015057 thrombin receptor activity(GO:0015057)
1.3 20.3 GO:0005522 profilin binding(GO:0005522)
1.2 3.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.2 6.0 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
1.2 5.9 GO:0050692 DBD domain binding(GO:0050692)
1.2 3.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
1.1 26.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.1 19.1 GO:0003993 acid phosphatase activity(GO:0003993)
1.1 10.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1 4.4 GO:0036033 mediator complex binding(GO:0036033)
1.1 4.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.1 62.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.1 59.5 GO:0042169 SH2 domain binding(GO:0042169)
1.1 14.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.0 9.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.0 16.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.0 6.1 GO:0048408 epidermal growth factor binding(GO:0048408)
1.0 5.7 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
1.0 2.9 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.9 40.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.9 31.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.9 8.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.9 4.7 GO:0051425 PTB domain binding(GO:0051425)
0.9 2.8 GO:0008384 IkappaB kinase activity(GO:0008384)
0.9 5.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.9 23.1 GO:0004697 protein kinase C activity(GO:0004697)
0.9 2.8 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.9 16.5 GO:0043495 protein anchor(GO:0043495)
0.9 22.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.9 2.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.9 22.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.9 2.7 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.9 28.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.9 10.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 2.6 GO:0052600 diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.9 9.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.8 2.5 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8 9.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.8 4.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.8 21.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.8 4.1 GO:0070051 fibrinogen binding(GO:0070051)
0.8 44.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.8 10.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.8 3.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.8 3.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.8 7.5 GO:0050733 RS domain binding(GO:0050733)
0.7 6.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.7 2.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.7 2.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.7 2.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.7 3.7 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.7 5.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.7 5.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.7 7.3 GO:0033691 sialic acid binding(GO:0033691)
0.7 52.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7 4.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.7 5.0 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.7 8.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.7 14.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 3.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.7 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 7.5 GO:0070990 snRNP binding(GO:0070990)
0.7 10.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.7 6.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.7 10.0 GO:0051525 NFAT protein binding(GO:0051525)
0.7 2.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.6 14.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 16.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 8.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.6 3.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.6 3.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.6 4.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.6 2.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 15.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.6 33.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 8.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 5.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 14.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.6 4.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 4.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.6 5.6 GO:0004064 arylesterase activity(GO:0004064)
0.5 3.2 GO:0019003 GDP binding(GO:0019003)
0.5 9.2 GO:0001727 lipid kinase activity(GO:0001727)
0.5 0.5 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.5 18.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 10.1 GO:0043274 phospholipase binding(GO:0043274)
0.5 6.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 5.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 81.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 8.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.5 10.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 6.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.5 8.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.5 16.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 13.6 GO:0032183 SUMO binding(GO:0032183)
0.5 6.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.5 8.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.5 2.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.5 2.3 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5 4.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 3.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.5 2.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.5 1.4 GO:0098808 mRNA cap binding(GO:0098808)
0.5 2.7 GO:0019961 interferon binding(GO:0019961)
0.5 1.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.5 1.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.4 3.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 70.2 GO:0017124 SH3 domain binding(GO:0017124)
0.4 1.7 GO:0043532 angiostatin binding(GO:0043532)
0.4 1.7 GO:0004335 galactokinase activity(GO:0004335)
0.4 2.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.4 1.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 1.6 GO:0003883 CTP synthase activity(GO:0003883)
0.4 3.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 10.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.4 3.2 GO:0001849 complement component C1q binding(GO:0001849)
0.4 8.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 13.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 11.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 138.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.4 4.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 5.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.4 8.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 1.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.4 3.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 3.5 GO:1901612 cardiolipin binding(GO:1901612)
0.3 3.5 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 3.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 20.1 GO:0019843 rRNA binding(GO:0019843)
0.3 4.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 12.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 2.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 2.0 GO:0004645 phosphorylase activity(GO:0004645)
0.3 0.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.3 8.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 15.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 20.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3 1.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 3.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 1.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 21.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 2.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 10.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 3.7 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.5 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.3 16.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.3 2.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 24.3 GO:0035064 methylated histone binding(GO:0035064)
0.3 8.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 1.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 1.5 GO:0070728 leucine binding(GO:0070728)
0.3 3.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 48.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 2.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 6.6 GO:0008432 JUN kinase binding(GO:0008432)
0.3 3.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 7.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 1.3 GO:0032027 myosin light chain binding(GO:0032027)
0.3 26.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 1.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 14.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 17.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.0 GO:0035197 siRNA binding(GO:0035197)
0.2 5.9 GO:0030515 snoRNA binding(GO:0030515)
0.2 8.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 11.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.7 GO:0004615 phosphomannomutase activity(GO:0004615)
0.2 2.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 6.5 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 6.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 2.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 24.2 GO:0004540 ribonuclease activity(GO:0004540)
0.2 4.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 3.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.5 GO:0034452 dynactin binding(GO:0034452)
0.2 1.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 3.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.8 GO:0045159 myosin II binding(GO:0045159)
0.2 2.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 2.3 GO:0031996 thioesterase binding(GO:0031996)
0.2 2.7 GO:0015197 peptide transporter activity(GO:0015197)
0.2 5.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.6 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.2 3.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.7 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 6.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 0.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 23.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 3.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 2.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 6.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.7 GO:0000339 RNA cap binding(GO:0000339)
0.2 3.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 14.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 3.8 GO:0001618 virus receptor activity(GO:0001618)
0.2 2.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 5.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 2.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 4.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 10.6 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 6.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 3.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 4.4 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 2.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 3.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.1 GO:0008494 translation activator activity(GO:0008494)
0.1 1.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 2.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 3.6 GO:0004527 exonuclease activity(GO:0004527)
0.1 0.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 8.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 4.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 5.8 GO:0004386 helicase activity(GO:0004386)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 3.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 3.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.5 GO:0089720 caspase binding(GO:0089720)
0.1 2.8 GO:0022829 wide pore channel activity(GO:0022829)
0.1 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.5 GO:0008009 chemokine activity(GO:0008009)
0.1 4.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 51.5 GO:0003682 chromatin binding(GO:0003682)
0.1 2.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.1 11.1 GO:0001047 core promoter binding(GO:0001047)
0.1 2.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.3 GO:0019978 interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978)
0.1 2.3 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 5.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 4.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 4.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 4.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 9.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 8.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 25.0 GO:0005525 GTP binding(GO:0005525)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.1 GO:0001614 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 89.8 GO:0003677 DNA binding(GO:0003677)
0.1 9.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.4 GO:0003924 GTPase activity(GO:0003924)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 3.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 6.3 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 4.7 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.9 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0070815 histone demethylase activity(GO:0032452) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 288.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
2.0 68.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.9 45.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.7 28.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.6 11.5 PID CD40 PATHWAY CD40/CD40L signaling
1.4 38.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.4 84.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.2 43.6 PID EPHA FWDPATHWAY EPHA forward signaling
1.1 17.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.9 48.2 PID BCR 5PATHWAY BCR signaling pathway
0.9 13.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.8 10.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8 27.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.7 5.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.7 11.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.7 7.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 37.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.7 4.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 65.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.6 32.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.6 20.2 PID MYC PATHWAY C-MYC pathway
0.6 16.9 PID IL27 PATHWAY IL27-mediated signaling events
0.6 35.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.6 30.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.5 39.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 22.0 PID ATR PATHWAY ATR signaling pathway
0.5 28.2 PID PLK1 PATHWAY PLK1 signaling events
0.5 7.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 9.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.5 23.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.5 18.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 13.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.4 9.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 14.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 12.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 5.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 10.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 6.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.4 5.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 6.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.4 6.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 13.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 12.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 31.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 10.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 22.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 32.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.3 1.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 6.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 7.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 7.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 12.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.3 3.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 10.0 PID AURORA B PATHWAY Aurora B signaling
0.3 12.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 5.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 3.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 8.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 2.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 1.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 3.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 13.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 5.5 PID TNF PATHWAY TNF receptor signaling pathway
0.2 3.5 PID ARF6 PATHWAY Arf6 signaling events
0.2 5.9 PID E2F PATHWAY E2F transcription factor network
0.2 8.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 10.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 5.7 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 19.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 4.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 132.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
4.2 42.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
2.2 127.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.0 11.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.9 37.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
1.8 104.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
1.8 12.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.7 12.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
1.6 20.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.6 15.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.5 3.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.5 20.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.5 18.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.4 64.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.4 22.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.4 22.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.3 83.8 REACTOME G1 PHASE Genes involved in G1 Phase
1.1 20.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
1.0 33.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
1.0 6.0 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.0 15.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 6.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 111.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.9 11.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.9 14.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.9 5.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.9 8.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.9 10.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.8 38.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.8 43.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.7 31.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.7 14.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.7 11.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.6 4.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.6 12.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.6 36.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.6 16.3 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.6 7.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 12.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6 3.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.5 17.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 13.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.5 6.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.5 5.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 8.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 7.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.5 6.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.5 66.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.5 2.4 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.5 42.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.5 5.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 1.4 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.4 5.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 6.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.4 28.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.4 5.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.4 14.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.4 6.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.4 4.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 3.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 6.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 3.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 6.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 21.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 8.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.3 9.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 13.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 7.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 3.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.3 2.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.3 6.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 3.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 7.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 11.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 5.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 6.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 3.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 7.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 0.7 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.2 1.4 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.2 2.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 3.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 7.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 3.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 7.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 8.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 2.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 4.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 7.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 5.3 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.1 1.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 7.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 5.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 5.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 5.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME TRANSLATION Genes involved in Translation
0.0 2.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall