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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Etv3_Erf_Fev_Elk4_Elk1_Elk3

Z-value: 3.02

Motif logo

Transcription factors associated with Etv3_Erf_Fev_Elk4_Elk1_Elk3

Gene Symbol Gene ID Gene Info
ENSMUSG00000003382.19 Etv3
ENSMUSG00000040857.16 Erf
ENSMUSG00000055197.5 Fev
ENSMUSG00000026436.16 Elk4
ENSMUSG00000009406.14 Elk1
ENSMUSG00000008398.17 Elk3

Activity-expression correlation:

Activity profile of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Sorted Z-values of Etv3_Erf_Fev_Elk4_Elk1_Elk3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv3_Erf_Fev_Elk4_Elk1_Elk3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_48707763 86.18 ENSMUST00000140800.2
tripartite motif-containing 41
chr11_-_48708159 84.74 ENSMUST00000047145.14
tripartite motif-containing 41
chr9_-_60595401 36.46 ENSMUST00000114034.9
ENSMUST00000065603.12
leucine rich repeat containing 49
chr2_+_91480513 34.06 ENSMUST00000090614.11
Rho GTPase activating protein 1
chr1_-_121255448 32.71 ENSMUST00000186915.2
ENSMUST00000160968.8
ENSMUST00000162582.2
insulin induced gene 2
chr1_-_121255503 30.02 ENSMUST00000160688.2
insulin induced gene 2
chr1_-_121255400 29.08 ENSMUST00000159085.8
ENSMUST00000159125.2
ENSMUST00000161818.2
insulin induced gene 2
chr17_+_35354172 27.26 ENSMUST00000172571.8
ENSMUST00000173491.8
BCL2-associated athanogene 6
chr1_-_121255753 26.76 ENSMUST00000003818.14
insulin induced gene 2
chr17_+_35354148 26.01 ENSMUST00000166426.9
ENSMUST00000025250.14
BCL2-associated athanogene 6
chr2_-_91480096 25.94 ENSMUST00000099714.10
ENSMUST00000111333.2
zinc finger protein 408
chr11_-_70537878 25.72 ENSMUST00000014750.15
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr17_+_35454833 24.35 ENSMUST00000118384.8
ATPase, H+ transporting, lysosomal V1 subunit G2
chr19_+_8897732 22.11 ENSMUST00000096243.7
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_+_91480460 21.84 ENSMUST00000111331.9
Rho GTPase activating protein 1
chr9_+_108167628 21.69 ENSMUST00000035227.8
nicolin 1
chr11_-_53321242 21.42 ENSMUST00000109019.8
ubiquinol-cytochrome c reductase, complex III subunit VII
chr17_+_34174797 21.39 ENSMUST00000173196.3
VPS52 GARP complex subunit
chr12_+_80690985 21.29 ENSMUST00000219405.2
ENSMUST00000085245.7
solute carrier family 39 (zinc transporter), member 9
chr8_-_26275182 21.25 ENSMUST00000038498.10
BCL2-associated athanogene 4
chr1_-_164135008 21.07 ENSMUST00000027866.11
ENSMUST00000120447.8
ENSMUST00000086032.4
basic leucine zipper nuclear factor 1
chr1_-_171122509 20.98 ENSMUST00000111302.4
ENSMUST00000080001.9
ubiquitin-fold modifier conjugating enzyme 1
chr11_-_6150411 20.75 ENSMUST00000066496.10
NudC domain containing 3
chr7_-_79392763 20.57 ENSMUST00000032761.8
peroxisomal biogenesis factor 11 alpha
chr2_-_12424189 20.41 ENSMUST00000124515.2
MINDY lysine 48 deubiquitinase 3
chr5_-_143255713 20.12 ENSMUST00000161448.8
zinc finger protein 316
chr5_+_111881790 19.78 ENSMUST00000180627.2
predicted gene, 26897
chr7_-_140462187 19.54 ENSMUST00000211179.2
sirtuin 3
chr4_-_124744454 19.25 ENSMUST00000125776.8
ENSMUST00000163946.2
ENSMUST00000106190.10
RIKEN cDNA 1110065P20 gene
chr2_-_12424212 19.22 ENSMUST00000124603.8
ENSMUST00000129993.3
ENSMUST00000028105.13
MINDY lysine 48 deubiquitinase 3
chr9_+_57818384 19.07 ENSMUST00000217129.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr17_+_29487881 18.71 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr9_-_29323032 18.68 ENSMUST00000115236.2
neurotrimin
chr9_+_117869642 18.54 ENSMUST00000134433.8
5-azacytidine induced gene 2
chr8_+_94763826 18.49 ENSMUST00000109556.9
ENSMUST00000093301.9
ENSMUST00000060632.8
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr9_+_110306020 18.43 ENSMUST00000198858.5
kinesin family member 9
chr9_+_117869577 18.41 ENSMUST00000133580.8
5-azacytidine induced gene 2
chr2_+_31462659 18.40 ENSMUST00000113482.8
far upstream element (FUSE) binding protein 3
chr5_-_103174794 18.28 ENSMUST00000128869.8
mitogen-activated protein kinase 10
chr9_+_117869543 18.24 ENSMUST00000044454.12
5-azacytidine induced gene 2
chr13_-_90237631 18.16 ENSMUST00000160232.8
X-ray repair complementing defective repair in Chinese hamster cells 4
chr7_-_140462221 18.15 ENSMUST00000026559.14
sirtuin 3
chr11_-_42073737 17.94 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr10_-_95159933 17.86 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_87683592 17.79 ENSMUST00000144047.8
ENSMUST00000027512.13
ENSMUST00000113186.8
ENSMUST00000113190.3
autophagy related 16-like 1 (S. cerevisiae)
chr10_-_126906123 17.60 ENSMUST00000060991.6
tetraspanin 31
chr2_+_73142945 17.57 ENSMUST00000090811.11
ENSMUST00000112050.2
secernin 3
chr11_-_51647204 17.57 ENSMUST00000109092.8
ENSMUST00000064297.5
Sec24 related gene family, member A (S. cerevisiae)
chr16_-_20549294 17.42 ENSMUST00000231826.2
ENSMUST00000076422.13
ENSMUST00000232217.2
thrombopoietin
chr17_+_35354430 17.24 ENSMUST00000173535.8
ENSMUST00000173952.8
BCL2-associated athanogene 6
chr9_-_29323500 16.90 ENSMUST00000115237.8
neurotrimin
chr19_+_6111204 16.87 ENSMUST00000162726.5
zinc finger, HIT domain containing 2
chr11_+_87482971 16.84 ENSMUST00000103179.10
ENSMUST00000092802.12
ENSMUST00000146871.8
myotubularin related protein 4
chr10_-_39901249 16.75 ENSMUST00000163705.3
major facilitator superfamily domain containing 4B1
chr17_+_35354655 16.52 ENSMUST00000174478.8
ENSMUST00000174281.9
ENSMUST00000173550.8
BCL2-associated athanogene 6
chr4_-_124744943 16.23 ENSMUST00000185036.2
RIKEN cDNA 1110065P20 gene
chr7_+_79910948 16.18 ENSMUST00000117989.2
neugrin, neurite outgrowth associated
chr15_-_103338814 16.11 ENSMUST00000147389.8
ENSMUST00000023129.15
gametocyte specific factor 1
chr18_-_56705960 16.05 ENSMUST00000174518.8
aldehyde dehydrogenase family 7, member A1
chr9_+_103940575 15.98 ENSMUST00000120854.8
acyl-Coenzyme A dehydrogenase family, member 11
chr15_-_103338671 15.88 ENSMUST00000129837.2
ENSMUST00000146675.8
ENSMUST00000153930.8
ENSMUST00000141364.8
gametocyte specific factor 1
chr9_+_57818243 15.53 ENSMUST00000216925.2
ENSMUST00000163329.2
ENSMUST00000213654.2
ENSMUST00000217132.2
ENSMUST00000216841.2
ENSMUST00000214086.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr1_+_164135230 15.30 ENSMUST00000193683.6
NME/NM23 family member 7
chr17_-_59320257 15.30 ENSMUST00000174122.2
ENSMUST00000025065.12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr14_-_55909314 15.25 ENSMUST00000163750.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr17_+_34174782 15.19 ENSMUST00000025178.17
VPS52 GARP complex subunit
chr3_+_32583681 15.16 ENSMUST00000147350.8
mitofusin 1
chr11_-_51647290 15.02 ENSMUST00000109097.9
Sec24 related gene family, member A (S. cerevisiae)
chr6_+_82018604 15.01 ENSMUST00000042974.15
eva-1 homolog A (C. elegans)
chrX_-_149800247 14.99 ENSMUST00000112691.9
ENSMUST00000026297.12
ENSMUST00000154393.8
ENSMUST00000156233.2
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr15_-_75952724 14.85 ENSMUST00000002599.11
ENSMUST00000100527.13
poly-U binding splicing factor 60
chr9_-_108338111 14.78 ENSMUST00000193895.6
kelch domain containing 8B
chr15_+_78761360 14.73 ENSMUST00000041587.8
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr2_+_65499097 14.57 ENSMUST00000200829.4
sodium channel, voltage-gated, type II, alpha
chr3_+_32583602 14.38 ENSMUST00000091257.11
mitofusin 1
chr2_-_168072295 14.35 ENSMUST00000154111.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr16_+_3690232 14.29 ENSMUST00000151988.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr9_+_110306052 14.23 ENSMUST00000197248.5
ENSMUST00000061155.12
ENSMUST00000198043.5
ENSMUST00000084952.8
kinesin family member 9
chr17_-_47998953 14.22 ENSMUST00000113301.2
ENSMUST00000113302.10
translocase of outer mitochondrial membrane 6
chr1_+_171910073 13.99 ENSMUST00000135192.8
coatomer protein complex subunit alpha
chr2_-_168072493 13.98 ENSMUST00000109193.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr6_+_8259288 13.87 ENSMUST00000159335.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr10_-_89568106 13.86 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr10_-_83484576 13.84 ENSMUST00000020500.14
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr3_+_138911648 13.74 ENSMUST00000062306.7
sperm tail PG rich repeat containing 2
chr6_+_124986224 13.71 ENSMUST00000112427.8
zinc finger protein 384
chr7_+_44499374 13.50 ENSMUST00000141311.8
ENSMUST00000107880.9
ENSMUST00000208384.2
AKT1 substrate 1 (proline-rich)
chr10_-_39775182 13.40 ENSMUST00000178045.9
ENSMUST00000178563.3
major facilitator superfamily domain containing 4B4
chr8_+_110806390 13.37 ENSMUST00000212754.2
ENSMUST00000058804.10
zinc finger protein 612
chr13_-_54897425 13.34 ENSMUST00000099506.2
G protein-regulated inducer of neurite outgrowth 1
chr11_+_6150029 13.32 ENSMUST00000181545.2
RIKEN cDNA A730071L15Rik gene
chr2_-_112198366 13.32 ENSMUST00000028551.4
ER membrane protein complex subunit 4
chr18_+_30405800 13.29 ENSMUST00000115812.10
ENSMUST00000115811.8
ENSMUST00000091978.12
phosphatidylinositol 3-kinase catalytic subunit type 3
chr2_+_163444248 13.26 ENSMUST00000152135.8
tocopherol (alpha) transfer protein-like
chr6_-_124718316 13.25 ENSMUST00000004389.6
gene rich cluster, C10 gene
chr17_-_26063391 13.19 ENSMUST00000176591.8
ras homolog family member T2
chr14_-_26390986 13.17 ENSMUST00000052932.10
phosphodiesterase 12
chr9_+_64940004 12.91 ENSMUST00000167773.2
dipeptidylpeptidase 8
chrX_-_12628309 12.89 ENSMUST00000096495.11
ENSMUST00000076016.6
mediator complex subunit 14
chr1_+_183078573 12.89 ENSMUST00000109166.8
axin interactor, dorsalization associated
chr3_+_138911419 12.87 ENSMUST00000106239.8
sperm tail PG rich repeat containing 2
chr4_+_155171034 12.82 ENSMUST00000030915.11
ENSMUST00000155775.8
ENSMUST00000127457.2
MORN repeat containing 1
chr15_-_55421144 12.71 ENSMUST00000172387.8
mitochondrial ribosomal protein L13
chr6_-_124942366 12.71 ENSMUST00000129446.8
ENSMUST00000032220.15
COP9 signalosome subunit 7A
chr17_+_29487762 12.65 ENSMUST00000064709.13
ENSMUST00000234711.2
cDNA sequence BC004004
chr18_+_62681982 12.62 ENSMUST00000055725.12
ENSMUST00000162365.8
serine peptidase inhibitor, Kazal type 10
chr7_-_100021514 12.61 ENSMUST00000032963.10
protein phosphatase methylesterase 1
chr16_-_56537545 12.53 ENSMUST00000141404.3
Trk-fused gene
chr9_-_60594742 12.51 ENSMUST00000114032.8
ENSMUST00000166168.8
ENSMUST00000132366.2
leucine rich repeat containing 49
chr16_-_56537650 12.31 ENSMUST00000128551.8
Trk-fused gene
chr11_-_44361289 12.31 ENSMUST00000102795.4
ubiquitin-like domain containing CTD phosphatase 1
chr2_-_130126339 12.26 ENSMUST00000239288.2
ENSMUST00000028892.11
isocitrate dehydrogenase 3 (NAD+) beta
chr9_+_27210500 12.18 ENSMUST00000214357.2
ENSMUST00000115247.8
ENSMUST00000133213.3
immunoglobulin superfamily, member 9B
chr7_+_44499818 12.13 ENSMUST00000136232.2
ENSMUST00000207223.2
AKT1 substrate 1 (proline-rich)
chr1_+_171910343 12.05 ENSMUST00000027833.12
coatomer protein complex subunit alpha
chr11_+_94544593 11.97 ENSMUST00000025278.8
mitochondrial ribosomal protein L27
chr17_-_26063488 11.96 ENSMUST00000176709.2
ras homolog family member T2
chr6_-_124942170 11.93 ENSMUST00000148485.2
ENSMUST00000129976.8
COP9 signalosome subunit 7A
chr9_+_64939695 11.92 ENSMUST00000034960.14
dipeptidylpeptidase 8
chr6_+_124986193 11.90 ENSMUST00000112428.8
zinc finger protein 384
chr13_-_90237713 11.89 ENSMUST00000022115.14
X-ray repair complementing defective repair in Chinese hamster cells 4
chr1_-_183078488 11.85 ENSMUST00000057062.12
BRO1 domain and CAAX motif containing
chr14_-_119336809 11.84 ENSMUST00000156203.8
UDP-glucose glycoprotein glucosyltransferase 2
chr16_-_43959361 11.83 ENSMUST00000124102.8
ATPase, H+ transporting, lysosomal V1 subunit A
chr5_+_122529941 11.80 ENSMUST00000102525.11
actin related protein 2/3 complex, subunit 3
chr13_-_54897660 11.66 ENSMUST00000135343.2
G protein-regulated inducer of neurite outgrowth 1
chr7_-_92286287 11.65 ENSMUST00000056106.14
ENSMUST00000138267.2
ENSMUST00000118157.8
ankyrin repeat domain 42
chr17_-_34159273 11.63 ENSMUST00000179418.9
ENSMUST00000174048.8
ENSMUST00000174426.2
ENSMUST00000173678.3
ENSMUST00000025163.14
prefoldin subunit 6
chr12_-_31549538 11.62 ENSMUST00000064240.14
ENSMUST00000185739.8
ENSMUST00000188326.3
ENSMUST00000101499.10
ENSMUST00000085487.12
Casitas B-lineage lymphoma-like 1
chr3_-_116601451 11.57 ENSMUST00000159670.3
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr12_+_85157607 11.55 ENSMUST00000053811.10
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr2_-_170248421 11.51 ENSMUST00000154650.8
breast carcinoma amplified sequence 1
chr7_+_109617456 11.44 ENSMUST00000084731.5
importin 7
chr4_+_118266582 11.36 ENSMUST00000144577.2
mediator complex subunit 8
chr14_-_55909527 11.36 ENSMUST00000010520.10
neural precursor cell expressed, developmentally down-regulated gene 8
chr4_+_138032035 11.35 ENSMUST00000030538.5
dolichyl-di-phosphooligosaccharide-protein glycotransferase
chr5_-_92582969 11.30 ENSMUST00000135112.8
nucleoporin 54
chr6_-_124942457 11.23 ENSMUST00000112439.9
COP9 signalosome subunit 7A
chr2_+_74656145 11.18 ENSMUST00000028511.8
metaxin 2
chr12_+_65012564 11.12 ENSMUST00000066296.9
ENSMUST00000223166.2
TOG array regulator of axonemal microtubules 1
chr16_-_56537808 11.03 ENSMUST00000065515.14
Trk-fused gene
chr12_+_9023892 10.97 ENSMUST00000085745.13
ENSMUST00000111113.3
WD repeat domain 35
chr2_-_155356716 10.97 ENSMUST00000029131.11
gamma-glutamyltransferase 7
chr8_+_114362181 10.87 ENSMUST00000179926.9
MON1 homolog B, secretory traffciking associated
chr7_+_121732258 10.79 ENSMUST00000033156.5
dynactin 5
chr7_-_6158925 10.79 ENSMUST00000207957.2
ENSMUST00000094870.3
ENSMUST00000207628.2
zinc finger protein 787
chr8_+_120121612 10.77 ENSMUST00000098367.5
malonyl-CoA decarboxylase
chr17_+_13135216 10.74 ENSMUST00000089024.13
ENSMUST00000151287.8
t-complex protein 1
chr6_-_29609810 10.73 ENSMUST00000012679.15
transportin 3
chr5_+_67464284 10.72 ENSMUST00000113676.6
ENSMUST00000162372.8
solute carrier family 30 (zinc transporter), member 9
chr14_+_20724378 10.55 ENSMUST00000224492.2
ENSMUST00000223751.2
ENSMUST00000225108.2
ENSMUST00000224754.2
Sec24 related gene family, member C (S. cerevisiae)
chr12_-_84408576 10.46 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr16_-_90731611 10.41 ENSMUST00000149833.8
cilia and flagella associate protien 298
chr7_-_30325565 10.40 ENSMUST00000075738.6
cytochrome c oxidase, subunit 6B1
chr7_+_142623241 10.35 ENSMUST00000137856.2
tumor-suppressing subchromosomal transferable fragment 4
chr19_+_46587523 10.34 ENSMUST00000138302.9
ENSMUST00000099376.11
WW domain binding protein 1 like
chr13_-_90237179 10.33 ENSMUST00000161396.2
X-ray repair complementing defective repair in Chinese hamster cells 4
chr11_-_59730569 10.33 ENSMUST00000141415.2
COP9 signalosome subunit 3
chr10_-_57408512 10.31 ENSMUST00000169122.8
serine incorporator 1
chr9_+_21504018 10.20 ENSMUST00000062125.11
translocase of inner mitochondrial membrane 29
chr3_-_116601700 10.20 ENSMUST00000159742.8
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr7_+_46445512 10.15 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr7_-_30325514 10.12 ENSMUST00000208838.2
cytochrome c oxidase, subunit 6B1
chr11_-_86574586 10.11 ENSMUST00000018315.10
vacuole membrane protein 1
chr17_-_85397627 10.11 ENSMUST00000072406.5
ENSMUST00000171795.9
ENSMUST00000234676.2
prolyl endopeptidase-like
chr8_+_123939596 10.09 ENSMUST00000212892.2
ENSMUST00000212161.2
ENSMUST00000060133.8
ENSMUST00000212346.2
ENSMUST00000212637.2
spermatogenesis associated 33
chr15_+_58805605 10.04 ENSMUST00000022980.5
NADH:ubiquinone oxidoreductase subunit B9
chr19_+_10872587 10.04 ENSMUST00000025642.14
pre-mRNA processing factor 19
chr2_-_73216743 10.00 ENSMUST00000112044.8
ENSMUST00000112043.8
ENSMUST00000076463.12
G protein-coupled receptor 155
chr1_-_171910324 9.95 ENSMUST00000003550.11
nicastrin
chr1_-_91386976 9.95 ENSMUST00000069620.10
period circadian clock 2
chr9_+_20556088 9.93 ENSMUST00000162303.8
ENSMUST00000161486.8
ubiquitin-like 5
chr2_+_145745154 9.92 ENSMUST00000110000.8
ENSMUST00000002805.14
ENSMUST00000169732.8
ENSMUST00000134759.3
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr3_-_89152320 9.87 ENSMUST00000107464.8
ENSMUST00000090924.13
tripartite motif-containing 46
chr6_+_86826470 9.84 ENSMUST00000089519.13
ENSMUST00000204414.3
AP2 associated kinase 1
chrX_-_168103266 9.83 ENSMUST00000033717.9
ENSMUST00000112115.2
holocytochrome c synthetase
chr11_-_42072990 9.78 ENSMUST00000205546.2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr12_-_87312994 9.77 ENSMUST00000072744.15
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr8_+_26275560 9.75 ENSMUST00000211168.2
LSM1 homolog, mRNA degradation associated
chr7_+_5083212 9.69 ENSMUST00000098845.10
ENSMUST00000146317.8
ENSMUST00000153169.2
ENSMUST00000045277.7
epsin 1
chr8_+_123939566 9.68 ENSMUST00000212760.2
ENSMUST00000212523.2
spermatogenesis associated 33
chr11_-_59730654 9.67 ENSMUST00000019517.10
COP9 signalosome subunit 3
chr16_-_38342949 9.66 ENSMUST00000002925.6
translocase of inner mitochondrial membrane domain containing 1
chr15_+_99290832 9.63 ENSMUST00000160635.8
ENSMUST00000161250.8
ENSMUST00000229392.2
ENSMUST00000161778.8
transmembrane BAX inhibitor motif containing 6
chr12_-_87312982 9.62 ENSMUST00000179379.9
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr19_-_38807600 9.60 ENSMUST00000025963.8
NOC3 like DNA replication regulator
chr1_-_63215812 9.49 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr16_-_87229367 9.47 ENSMUST00000232095.2
listerin E3 ubiquitin protein ligase 1
chr5_-_3852857 9.46 ENSMUST00000043551.11
ankyrin repeat and IBR domain containing 1
chr15_-_77813123 9.46 ENSMUST00000109748.9
ENSMUST00000109747.9
ENSMUST00000100486.6
ENSMUST00000005487.12
thioredoxin 2
chr6_+_124986078 9.43 ENSMUST00000054553.11
zinc finger protein 384
chr16_-_90731394 9.39 ENSMUST00000142340.2
cilia and flagella associate protien 298
chr7_-_105289515 9.38 ENSMUST00000133519.8
ENSMUST00000209550.2
ENSMUST00000210911.2
ENSMUST00000084782.10
ENSMUST00000131446.8
ADP-ribosylation factor interacting protein 2
chr13_+_90237824 9.36 ENSMUST00000012566.9
transmembrane protein 167
chr12_-_44257109 9.32 ENSMUST00000015049.5
DnaJ heat shock protein family (Hsp40) member B9
chr10_-_80736579 9.32 ENSMUST00000218481.2
ENSMUST00000219896.2
ENSMUST00000020440.7
translocase of inner mitochondrial membrane 13
chr2_-_121287174 9.32 ENSMUST00000110613.9
ENSMUST00000056312.10
serine incorporator 4
chr2_+_145776720 9.29 ENSMUST00000152515.8
ENSMUST00000138774.8
ENSMUST00000130168.8
ENSMUST00000133433.8
ENSMUST00000118002.2
cilia and flagella associated protein 61
chr12_+_84408803 9.27 ENSMUST00000110278.8
ENSMUST00000145522.2
coenzyme Q6 monooxygenase
chr19_+_11747721 9.26 ENSMUST00000167199.3
mitochondrial ribosomal protein L16

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 36.6 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
10.9 87.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
10.8 54.2 GO:0044565 dendritic cell proliferation(GO:0044565)
9.6 57.6 GO:0032439 endosome localization(GO:0032439)
7.1 21.2 GO:0090367 negative regulation of mRNA modification(GO:0090367)
7.0 34.8 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
6.6 118.6 GO:0060363 cranial suture morphogenesis(GO:0060363)
6.4 19.3 GO:0019085 early viral transcription(GO:0019085)
6.2 18.7 GO:1901254 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
5.1 20.5 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
4.9 24.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
4.9 14.8 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
4.6 18.4 GO:0038016 insulin receptor internalization(GO:0038016)
4.5 13.5 GO:0071569 protein ufmylation(GO:0071569)
4.4 17.8 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
4.2 12.5 GO:0046038 GMP catabolic process(GO:0046038)
4.1 20.6 GO:0044375 regulation of peroxisome size(GO:0044375)
4.0 28.3 GO:0019348 dolichol metabolic process(GO:0019348)
4.0 19.9 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
3.9 73.7 GO:0000338 protein deneddylation(GO:0000338)
3.8 23.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
3.8 15.3 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
3.7 14.7 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
3.6 14.5 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
3.6 14.5 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
3.6 10.8 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
3.6 10.7 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
3.4 13.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
3.2 19.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
3.2 54.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
3.2 16.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
3.2 19.0 GO:0034227 tRNA thio-modification(GO:0034227)
3.1 9.4 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
3.1 27.6 GO:0006449 regulation of translational termination(GO:0006449)
3.1 15.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
3.1 9.2 GO:0018003 peptidyl-lysine N6-acetylation(GO:0018003)
3.1 21.4 GO:0021539 subthalamus development(GO:0021539)
3.0 9.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
2.9 5.9 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.9 37.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
2.8 19.6 GO:0007258 JUN phosphorylation(GO:0007258)
2.8 11.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
2.8 19.5 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
2.8 2.8 GO:1904431 positive regulation of t-circle formation(GO:1904431)
2.7 16.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
2.7 8.1 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
2.7 24.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.7 34.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
2.7 13.3 GO:0036343 psychomotor behavior(GO:0036343)
2.6 31.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
2.6 5.2 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
2.6 12.8 GO:0010796 regulation of multivesicular body size(GO:0010796)
2.5 12.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
2.4 35.3 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
2.3 13.9 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
2.3 6.8 GO:1990705 cholangiocyte proliferation(GO:1990705)
2.1 8.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
2.1 10.6 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
2.1 12.5 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
2.1 8.2 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
2.0 6.1 GO:0035627 ceramide transport(GO:0035627)
1.9 3.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.9 19.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
1.9 5.7 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
1.9 7.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
1.9 9.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.9 5.6 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
1.8 9.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
1.8 10.8 GO:0006742 NADP catabolic process(GO:0006742)
1.8 7.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
1.8 7.1 GO:0051031 tRNA transport(GO:0051031)
1.7 5.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
1.7 5.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.7 59.7 GO:0017004 cytochrome complex assembly(GO:0017004)
1.7 6.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
1.6 14.6 GO:0006102 isocitrate metabolic process(GO:0006102)
1.6 4.9 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
1.6 40.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
1.6 36.4 GO:0071420 cellular response to histamine(GO:0071420)
1.6 7.8 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
1.5 24.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.5 7.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.5 30.9 GO:0045792 negative regulation of cell size(GO:0045792)
1.5 20.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.5 5.8 GO:0007227 signal transduction downstream of smoothened(GO:0007227) positive regulation of hh target transcription factor activity(GO:0007228)
1.5 4.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.4 11.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
1.4 5.7 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.4 4.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.4 44.1 GO:0045116 protein neddylation(GO:0045116)
1.4 8.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
1.4 19.5 GO:0042407 cristae formation(GO:0042407)
1.4 2.8 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.4 17.8 GO:0006983 ER overload response(GO:0006983)
1.3 5.4 GO:0051182 coenzyme transport(GO:0051182)
1.3 4.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.3 14.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.3 2.6 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.3 3.9 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.3 16.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
1.3 38.2 GO:0051654 establishment of mitochondrion localization(GO:0051654)
1.3 3.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.2 21.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
1.2 32.4 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
1.2 5.0 GO:0006624 vacuolar protein processing(GO:0006624)
1.2 17.3 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
1.2 6.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
1.2 3.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.2 3.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.2 23.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
1.2 8.3 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.2 14.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.2 51.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.1 2.3 GO:0016559 peroxisome fission(GO:0016559)
1.1 7.8 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.1 5.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
1.1 35.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
1.1 3.3 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.1 63.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
1.1 19.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.1 3.2 GO:0042128 nitrate assimilation(GO:0042128)
1.0 13.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
1.0 4.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.0 9.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.0 4.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
1.0 21.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
1.0 10.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.0 2.9 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
1.0 1.9 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.9 2.8 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.9 8.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.9 13.9 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.9 52.6 GO:0032543 mitochondrial translation(GO:0032543)
0.9 2.7 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.9 5.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 5.5 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.9 78.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.9 2.7 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.9 4.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.9 29.4 GO:0071801 regulation of podosome assembly(GO:0071801)
0.9 2.7 GO:0051030 snRNA transport(GO:0051030)
0.9 3.5 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.9 6.2 GO:0006266 DNA ligation(GO:0006266)
0.9 2.6 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.9 12.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.9 17.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 3.4 GO:0010286 heat acclimation(GO:0010286)
0.8 5.9 GO:1902861 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.8 4.2 GO:0001692 histamine metabolic process(GO:0001692)
0.8 2.5 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.8 3.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.8 1.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.8 10.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.8 3.2 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.8 1.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.8 7.1 GO:0019695 choline metabolic process(GO:0019695)
0.8 11.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.8 3.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) cap-dependent translational initiation(GO:0002191)
0.8 11.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.8 8.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.8 10.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.8 1.6 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.8 2.3 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.8 38.0 GO:0006829 zinc II ion transport(GO:0006829)
0.8 1.5 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.8 3.8 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.8 4.6 GO:0022615 protein to membrane docking(GO:0022615)
0.8 6.1 GO:0051715 cytolysis in other organism(GO:0051715)
0.8 12.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.7 3.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.7 5.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.7 9.6 GO:0046051 UTP metabolic process(GO:0046051)
0.7 12.6 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.7 0.7 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861)
0.7 17.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.7 5.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.7 3.7 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.7 5.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.7 42.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.7 15.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.7 2.9 GO:0002188 translation reinitiation(GO:0002188)
0.7 2.1 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.7 2.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.7 3.5 GO:0042412 taurine biosynthetic process(GO:0042412)
0.7 2.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.7 2.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.7 28.6 GO:1901998 toxin transport(GO:1901998)
0.7 1.4 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.7 6.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.7 7.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7 8.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.7 6.7 GO:0015879 carnitine transport(GO:0015879)
0.7 6.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.7 14.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.7 8.6 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.7 5.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.7 6.0 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.6 1.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.6 1.9 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.6 8.4 GO:0048102 autophagic cell death(GO:0048102)
0.6 5.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.6 16.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.6 1.9 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.6 7.6 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.6 6.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.6 3.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.6 3.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.6 2.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 3.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 2.3 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.6 26.2 GO:0015992 proton transport(GO:0015992)
0.6 4.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.6 9.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.6 6.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.6 3.9 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 10.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.6 2.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.6 1.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.5 11.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.5 2.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.5 2.1 GO:1901993 pachytene(GO:0000239) meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993)
0.5 1.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.5 1.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.5 2.6 GO:0034214 protein hexamerization(GO:0034214)
0.5 3.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 1.5 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.5 3.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.5 4.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 9.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.5 2.4 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.5 7.3 GO:0030049 muscle filament sliding(GO:0030049)
0.5 12.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.5 1.4 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.5 1.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.5 4.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 24.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.5 4.7 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.5 10.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.5 1.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 4.1 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.5 6.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.5 3.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.4 3.6 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.4 0.4 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.4 3.9 GO:0009249 protein lipoylation(GO:0009249)
0.4 4.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4 1.3 GO:0046491 L-methylmalonyl-CoA metabolic process(GO:0046491)
0.4 8.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.4 10.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.4 7.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.4 2.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 1.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.4 9.0 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 2.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 2.0 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.4 9.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4 1.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.4 2.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.4 10.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.4 1.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.4 2.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 2.3 GO:0015867 ATP transport(GO:0015867)
0.4 6.6 GO:0051601 exocyst localization(GO:0051601)
0.4 2.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 2.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 13.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 3.4 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.4 7.1 GO:0046415 urate metabolic process(GO:0046415)
0.4 17.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.4 5.1 GO:0006544 glycine metabolic process(GO:0006544)
0.4 17.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.4 7.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.4 3.6 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.4 3.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 2.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.3 3.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 2.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 2.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 7.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 8.0 GO:0009060 aerobic respiration(GO:0009060)
0.3 4.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 12.1 GO:0034205 beta-amyloid formation(GO:0034205)
0.3 2.9 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 2.2 GO:0061743 motor learning(GO:0061743)
0.3 3.5 GO:0006020 inositol metabolic process(GO:0006020)
0.3 1.6 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 1.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.3 0.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.3 3.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 8.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.3 2.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.3 4.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.3 0.9 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.3 0.6 GO:0080154 regulation of fertilization(GO:0080154)
0.3 5.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 6.5 GO:0022900 electron transport chain(GO:0022900)
0.3 4.7 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.3 4.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.4 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.3 1.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.3 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 2.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 4.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457) maintenance of protein localization in organelle(GO:0072595)
0.3 27.0 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 1.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 1.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 0.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 13.4 GO:0018196 peptidyl-asparagine modification(GO:0018196)
0.3 4.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 3.1 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.3 0.8 GO:1903028 asymmetric Golgi ribbon formation(GO:0090164) regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.3 2.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 1.3 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.3 3.5 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.5 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.2 2.0 GO:0030242 pexophagy(GO:0030242)
0.2 3.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 13.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.2 4.0 GO:0030238 male sex determination(GO:0030238)
0.2 1.9 GO:0006517 protein deglycosylation(GO:0006517)
0.2 0.2 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 4.4 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.2 1.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 2.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 5.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 3.7 GO:0070166 enamel mineralization(GO:0070166)
0.2 15.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 0.5 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 12.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.2 13.9 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 1.8 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 5.9 GO:0045333 cellular respiration(GO:0045333)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 3.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 2.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 2.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 1.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 2.2 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 0.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 0.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 0.6 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.2 30.1 GO:0006839 mitochondrial transport(GO:0006839)
0.2 4.8 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 1.5 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.2 1.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 0.7 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 1.1 GO:0035878 nail development(GO:0035878)
0.2 1.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 2.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 13.9 GO:0046324 regulation of glucose import(GO:0046324)
0.2 1.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 4.2 GO:0006817 phosphate ion transport(GO:0006817)
0.2 4.6 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 7.9 GO:0060612 adipose tissue development(GO:0060612)
0.2 9.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 6.2 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.2 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 1.3 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 4.5 GO:0030539 male genitalia development(GO:0030539)
0.2 1.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 1.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.2 0.6 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 10.8 GO:0035904 aorta development(GO:0035904)
0.2 5.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 2.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.9 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 3.5 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.7 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.1 8.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 0.7 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 2.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 2.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 4.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 2.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.6 GO:0048820 hair follicle maturation(GO:0048820)
0.1 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 9.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 3.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 4.8 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.1 20.5 GO:0006457 protein folding(GO:0006457)
0.1 3.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 12.8 GO:0008643 carbohydrate transport(GO:0008643)
0.1 1.9 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 1.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 3.9 GO:0001706 endoderm formation(GO:0001706)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.0 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 2.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 3.1 GO:0003170 heart valve development(GO:0003170)
0.1 0.8 GO:0071800 podosome assembly(GO:0071800)
0.1 0.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.9 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 1.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 2.9 GO:0060416 response to growth hormone(GO:0060416)
0.1 4.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.6 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 1.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.8 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 3.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 13.9 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.1 0.8 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 1.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.4 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 0.5 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 9.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 5.1 GO:0006611 protein export from nucleus(GO:0006611)
0.1 15.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.1 2.3 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 2.8 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 3.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 2.9 GO:0001893 maternal placenta development(GO:0001893)
0.1 5.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 10.6 GO:0048675 axon extension(GO:0048675)
0.1 1.2 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 1.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 8.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 3.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 8.1 GO:0007565 female pregnancy(GO:0007565)
0.1 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 14.1 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 6.8 GO:0007050 cell cycle arrest(GO:0007050)
0.1 6.8 GO:0050821 protein stabilization(GO:0050821)
0.1 2.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.1 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.7 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117) microtubule severing(GO:0051013)
0.1 0.8 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 2.1 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.1 0.5 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 1.2 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 2.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.9 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 1.1 GO:0003016 respiratory system process(GO:0003016)
0.1 1.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 5.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 5.1 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.9 GO:0034644 cellular response to UV(GO:0034644)
0.1 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 12.3 GO:0006814 sodium ion transport(GO:0006814)
0.1 5.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.0 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:1905076 interleukin-17 secretion(GO:0072615) positive regulation of tumor necrosis factor secretion(GO:1904469) regulation of interleukin-17 secretion(GO:1905076)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 21.4 GO:0048232 male gamete generation(GO:0048232)
0.0 0.4 GO:0051770 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 2.2 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.0 GO:0009154 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.5 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.5 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 3.5 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.9 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 2.5 GO:0044782 cilium organization(GO:0044782)
0.0 0.5 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0097205 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0 3.2 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.8 GO:0051099 positive regulation of binding(GO:0051099)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.2 GO:0050808 synapse organization(GO:0050808)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.8 118.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
10.0 89.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
8.3 41.3 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
7.2 50.7 GO:0097443 sorting endosome(GO:0097443)
6.8 27.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
5.9 35.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
4.8 19.3 GO:0019034 viral replication complex(GO:0019034)
4.8 14.4 GO:0036501 UFD1-NPL4 complex(GO:0036501)
4.2 17.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
4.2 12.5 GO:1902560 GMP reductase complex(GO:1902560)
3.7 18.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
3.7 40.4 GO:0031931 TORC1 complex(GO:0031931)
3.6 21.3 GO:0070449 elongin complex(GO:0070449)
3.4 10.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
3.1 76.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
3.0 48.7 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
3.0 53.4 GO:0030127 COPII vesicle coat(GO:0030127)
2.8 8.5 GO:0016014 dystrobrevin complex(GO:0016014)
2.8 2.8 GO:0061574 ASAP complex(GO:0061574)
2.7 8.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.7 13.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
2.6 10.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.5 7.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
2.5 9.9 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
2.5 9.9 GO:1990769 proximal neuron projection(GO:1990769)
2.4 7.3 GO:0016461 unconventional myosin complex(GO:0016461)
2.4 9.5 GO:0031084 BLOC-2 complex(GO:0031084)
2.3 25.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
2.3 32.0 GO:0030126 COPI vesicle coat(GO:0030126)
2.3 2.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
2.2 17.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.1 16.6 GO:0061617 MICOS complex(GO:0061617)
2.0 20.1 GO:0031595 nuclear proteasome complex(GO:0031595)
2.0 47.9 GO:0030008 TRAPP complex(GO:0030008)
1.9 9.7 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
1.9 11.4 GO:0070876 SOSS complex(GO:0070876)
1.9 5.7 GO:0070985 TFIIK complex(GO:0070985)
1.9 9.4 GO:1990130 Iml1 complex(GO:1990130)
1.8 9.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.8 3.6 GO:0030314 junctional membrane complex(GO:0030314)
1.7 5.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
1.6 20.9 GO:0072546 ER membrane protein complex(GO:0072546)
1.5 6.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
1.5 7.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.5 15.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.5 35.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
1.4 4.3 GO:0098842 postsynaptic early endosome(GO:0098842)
1.4 4.3 GO:0018444 translation release factor complex(GO:0018444)
1.4 11.4 GO:0000439 core TFIIH complex(GO:0000439)
1.4 8.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.3 6.6 GO:0071797 LUBAC complex(GO:0071797)
1.3 36.4 GO:1902711 GABA-A receptor complex(GO:1902711)
1.3 5.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.3 66.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.3 19.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.3 35.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.2 73.1 GO:0008180 COP9 signalosome(GO:0008180)
1.2 25.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.2 9.7 GO:0070847 core mediator complex(GO:0070847)
1.2 18.0 GO:0017119 Golgi transport complex(GO:0017119)
1.2 1.2 GO:0030897 HOPS complex(GO:0030897)
1.2 3.5 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
1.2 21.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.2 12.8 GO:0016272 prefoldin complex(GO:0016272)
1.2 11.6 GO:0030991 intraciliary transport particle A(GO:0030991)
1.2 11.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.1 16.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.1 36.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.1 5.5 GO:0044316 cone cell pedicle(GO:0044316)
1.1 11.9 GO:0042587 glycogen granule(GO:0042587)
1.1 14.1 GO:0070765 gamma-secretase complex(GO:0070765)
1.0 69.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.0 5.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.0 9.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.0 13.2 GO:0071439 clathrin complex(GO:0071439)
1.0 41.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
1.0 11.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.0 4.0 GO:1990589 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589)
1.0 6.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.0 12.6 GO:0036156 inner dynein arm(GO:0036156)
1.0 9.6 GO:0034709 methylosome(GO:0034709)
0.9 12.2 GO:0034464 BBSome(GO:0034464)
0.9 3.7 GO:0071920 cleavage body(GO:0071920)
0.9 20.2 GO:0070069 cytochrome complex(GO:0070069)
0.9 6.3 GO:0089701 U2AF(GO:0089701)
0.9 5.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.9 12.9 GO:0031209 SCAR complex(GO:0031209)
0.9 6.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.8 18.4 GO:0000421 autophagosome membrane(GO:0000421)
0.8 15.0 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.8 22.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.8 12.3 GO:0005869 dynactin complex(GO:0005869)
0.8 6.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.8 2.4 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
0.8 2.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.8 3.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8 17.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.8 2.3 GO:0097361 CIA complex(GO:0097361)
0.7 10.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.7 5.0 GO:0097441 basilar dendrite(GO:0097441)
0.7 10.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 7.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.7 15.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.7 9.7 GO:0000813 ESCRT I complex(GO:0000813)
0.7 4.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.7 6.7 GO:0030478 actin cap(GO:0030478)
0.7 10.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.6 2.6 GO:0032021 NELF complex(GO:0032021)
0.6 3.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.6 5.5 GO:0097165 nuclear stress granule(GO:0097165)
0.6 4.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.6 1.8 GO:1902636 kinociliary basal body(GO:1902636)
0.6 9.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 10.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 3.5 GO:1990393 3M complex(GO:1990393)
0.6 5.1 GO:0000812 Swr1 complex(GO:0000812)
0.6 2.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 1.1 GO:0055087 Ski complex(GO:0055087)
0.6 4.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.5 4.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.5 1.6 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.5 21.1 GO:0016592 mediator complex(GO:0016592)
0.5 3.0 GO:0070695 FHF complex(GO:0070695)
0.5 1.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5 28.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 5.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 2.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 4.7 GO:0005642 annulate lamellae(GO:0005642)
0.5 178.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.5 2.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.5 23.0 GO:0005801 cis-Golgi network(GO:0005801)
0.4 96.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.4 11.5 GO:0005839 proteasome core complex(GO:0005839)
0.4 7.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 32.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 8.7 GO:0030914 STAGA complex(GO:0030914)
0.4 2.5 GO:0008537 proteasome activator complex(GO:0008537)
0.4 3.8 GO:0061689 tricellular tight junction(GO:0061689)
0.4 2.5 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.4 1.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.4 44.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 5.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 6.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 15.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.4 3.2 GO:0071986 Ragulator complex(GO:0071986)
0.4 3.5 GO:0097255 R2TP complex(GO:0097255)
0.4 1.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 10.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 3.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 6.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 1.5 GO:0035061 interchromatin granule(GO:0035061)
0.4 4.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.4 1.8 GO:0034448 EGO complex(GO:0034448)
0.4 3.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.4 16.5 GO:0002102 podosome(GO:0002102)
0.3 1.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.3 11.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 1.4 GO:0008623 CHRAC(GO:0008623)
0.3 3.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 1.0 GO:0034455 t-UTP complex(GO:0034455)
0.3 2.0 GO:1990909 Wnt signalosome(GO:1990909)
0.3 7.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 12.2 GO:0060077 inhibitory synapse(GO:0060077)
0.3 14.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 2.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 3.1 GO:0071203 WASH complex(GO:0071203)
0.3 27.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 8.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 7.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.3 3.5 GO:0032797 SMN complex(GO:0032797)
0.3 10.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 14.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 3.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 2.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 76.2 GO:0000139 Golgi membrane(GO:0000139)
0.2 1.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 5.0 GO:0000145 exocyst(GO:0000145)
0.2 11.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 4.7 GO:0030686 90S preribosome(GO:0030686)
0.2 1.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 27.7 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.2 9.5 GO:0043034 costamere(GO:0043034)
0.2 2.2 GO:0038201 TOR complex(GO:0038201)
0.2 2.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.9 GO:0005579 membrane attack complex(GO:0005579)
0.2 13.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 44.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 3.5 GO:0002080 acrosomal membrane(GO:0002080)
0.2 3.7 GO:0030904 retromer complex(GO:0030904)
0.2 1.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 1.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.7 GO:0070545 PeBoW complex(GO:0070545)
0.2 16.1 GO:0031594 neuromuscular junction(GO:0031594)
0.2 21.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 40.6 GO:0031965 nuclear membrane(GO:0031965)
0.2 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.2 34.6 GO:0005769 early endosome(GO:0005769)
0.2 10.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 4.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.6 GO:0022624 proteasome accessory complex(GO:0022624)
0.1 24.1 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0042382 paraspeckles(GO:0042382)
0.1 30.1 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.1 1.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 3.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 19.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.3 GO:0005811 lipid particle(GO:0005811)
0.1 159.5 GO:0005739 mitochondrion(GO:0005739)
0.1 1.3 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 12.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 115.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 1.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 2.8 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0002177 manchette(GO:0002177)
0.1 9.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 2.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 3.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 6.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 13.9 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.1 GO:0005605 basal lamina(GO:0005605)
0.1 1.9 GO:0001741 XY body(GO:0001741)
0.1 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 4.9 GO:0031514 motile cilium(GO:0031514)
0.0 5.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005685 U1 snRNP(GO:0005685)
0.0 9.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 1.4 GO:0030133 transport vesicle(GO:0030133)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 8.4 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.2 30.5 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
8.6 25.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
6.8 27.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
6.6 19.8 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
6.3 37.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
6.3 37.5 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
5.3 16.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
5.1 20.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
4.6 18.5 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
4.6 36.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.4 88.4 GO:0015643 toxic substance binding(GO:0015643)
4.2 12.5 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
4.0 16.0 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
3.9 19.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.8 15.3 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
3.7 22.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.7 14.7 GO:0072541 peroxynitrite reductase activity(GO:0072541)
3.6 18.2 GO:0051185 coenzyme transporter activity(GO:0051185)
3.6 10.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.3 19.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
3.2 25.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.9 14.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.9 11.5 GO:0016748 succinyltransferase activity(GO:0016748)
2.7 16.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
2.6 7.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
2.6 7.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
2.4 9.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.4 12.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
2.4 9.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
2.3 18.7 GO:0033592 RNA strand annealing activity(GO:0033592)
2.3 47.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.3 6.8 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
2.2 4.4 GO:0016979 lipoate-protein ligase activity(GO:0016979)
2.1 40.5 GO:0070403 NAD+ binding(GO:0070403)
2.1 12.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.1 6.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
2.1 2.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
2.1 41.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
2.0 6.1 GO:0004348 glucosylceramidase activity(GO:0004348)
2.0 4.1 GO:1904288 BAT3 complex binding(GO:1904288)
2.0 10.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.0 14.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
2.0 19.9 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
2.0 7.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
2.0 27.4 GO:0016783 sulfurtransferase activity(GO:0016783)
1.9 25.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.9 7.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.9 5.6 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.8 34.7 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
1.7 5.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
1.7 18.6 GO:0031419 cobalamin binding(GO:0031419)
1.6 4.9 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
1.5 46.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.5 9.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.5 5.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.5 14.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.4 8.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.4 13.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.3 4.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.3 14.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.3 28.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.3 9.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.3 18.9 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
1.2 6.1 GO:0097001 ceramide binding(GO:0097001)
1.2 18.0 GO:0000339 RNA cap binding(GO:0000339)
1.2 3.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
1.2 3.6 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
1.2 4.6 GO:0003998 acylphosphatase activity(GO:0003998)
1.2 8.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
1.1 14.9 GO:0046790 virion binding(GO:0046790)
1.1 19.4 GO:0043522 leucine zipper domain binding(GO:0043522)
1.1 6.7 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.1 6.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.1 17.8 GO:0031386 protein tag(GO:0031386)
1.1 4.4 GO:0034511 U3 snoRNA binding(GO:0034511)
1.1 12.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
1.0 37.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
1.0 8.2 GO:0017002 activin-activated receptor activity(GO:0017002)
1.0 4.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
1.0 4.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.0 7.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.0 9.9 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.0 2.9 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.9 3.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.9 11.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.9 20.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.9 6.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.9 2.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.9 2.6 GO:0004946 bombesin receptor activity(GO:0004946)
0.9 3.5 GO:0005047 signal recognition particle binding(GO:0005047)
0.8 32.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.8 2.5 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.8 4.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.8 16.7 GO:0051787 misfolded protein binding(GO:0051787)
0.8 3.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 8.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8 17.6 GO:0016805 dipeptidase activity(GO:0016805)
0.8 2.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.7 4.4 GO:0004645 phosphorylase activity(GO:0004645)
0.7 9.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.7 5.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.7 2.9 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.7 3.6 GO:0070012 oligopeptidase activity(GO:0070012)
0.7 7.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.7 11.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.7 28.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7 4.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.7 4.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 4.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.7 2.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.7 6.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 7.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.7 3.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.6 2.6 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.6 8.3 GO:0071253 connexin binding(GO:0071253)
0.6 5.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.6 2.5 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.6 28.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 1.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.6 4.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.6 3.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.6 1.3 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.6 9.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 4.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 3.7 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.6 14.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.6 3.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.6 2.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.6 10.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.6 8.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.6 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.6 11.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.6 2.4 GO:1990460 leptin receptor binding(GO:1990460)
0.6 48.7 GO:0051082 unfolded protein binding(GO:0051082)
0.6 15.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 16.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 8.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 2.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.6 16.4 GO:0071949 FAD binding(GO:0071949)
0.6 1.7 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.6 5.1 GO:0034452 dynactin binding(GO:0034452)
0.6 5.0 GO:0031432 titin binding(GO:0031432)
0.5 3.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.5 7.1 GO:0019003 GDP binding(GO:0019003)
0.5 2.2 GO:0051435 BH4 domain binding(GO:0051435)
0.5 2.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.5 9.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 30.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 20.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 5.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 1.5 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.5 11.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 6.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.5 4.6 GO:0015266 protein channel activity(GO:0015266)
0.5 97.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.5 3.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.5 4.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 4.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 1.4 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.5 6.2 GO:0050815 phosphoserine binding(GO:0050815)
0.5 2.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.5 2.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.5 3.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 9.8 GO:0031489 myosin V binding(GO:0031489)
0.4 3.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.4 10.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 2.6 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 2.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 10.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 1.3 GO:0032142 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.4 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 1.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 17.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 1.3 GO:0004493 methylmalonyl-CoA epimerase activity(GO:0004493)
0.4 24.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.4 4.5 GO:0035473 lipase binding(GO:0035473)
0.4 21.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.4 1.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 14.1 GO:0045503 dynein light chain binding(GO:0045503)
0.4 2.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.4 10.8 GO:0001671 ATPase activator activity(GO:0001671)
0.4 40.7 GO:0008565 protein transporter activity(GO:0008565)
0.4 3.2 GO:0050692 DBD domain binding(GO:0050692)
0.4 2.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.4 26.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 3.8 GO:0016531 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.4 2.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.4 3.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 7.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.4 8.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.4 2.9 GO:0034046 poly(G) binding(GO:0034046)
0.4 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.4 1.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4 0.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.3 2.8 GO:0048185 activin binding(GO:0048185)
0.3 110.7 GO:0003924 GTPase activity(GO:0003924)
0.3 4.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 5.0 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.3 2.9 GO:0004568 chitinase activity(GO:0004568)
0.3 1.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 1.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 7.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 1.6 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 1.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 2.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 3.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3 45.8 GO:0005179 hormone activity(GO:0005179)
0.3 1.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 14.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 6.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 2.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 19.8 GO:0051087 chaperone binding(GO:0051087)
0.3 0.3 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.3 3.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 7.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.3 3.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 7.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 2.9 GO:0070061 fructose-bisphosphate aldolase activity(GO:0004332) fructose binding(GO:0070061)
0.3 9.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 7.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 4.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 2.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.5 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 2.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 5.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 10.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 5.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 11.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 2.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 2.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 27.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 6.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 4.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 15.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 4.4 GO:0005537 mannose binding(GO:0005537)
0.2 4.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 122.8 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.2 1.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 171.6 GO:0008270 zinc ion binding(GO:0008270)
0.2 2.4 GO:0008097 5S rRNA binding(GO:0008097)
0.2 3.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 5.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 22.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.2 3.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 8.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 4.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 0.4 GO:0030984 kininogen binding(GO:0030984)
0.2 3.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 4.0 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.2 23.4 GO:0005262 calcium channel activity(GO:0005262)
0.2 3.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 22.1 GO:0002020 protease binding(GO:0002020)
0.2 2.3 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 0.8 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 0.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 3.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.8 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 3.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 0.5 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 1.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0009383 C-methyltransferase activity(GO:0008169) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 1.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 2.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 3.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 3.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 4.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.9 GO:0019841 retinol binding(GO:0019841)
0.1 1.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 5.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 48.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0016420 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) phosphopantetheine binding(GO:0031177)
0.1 25.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 23.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 1.5 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 5.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 4.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 8.0 GO:0000149 SNARE binding(GO:0000149)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 1.7 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.1 3.8 GO:0005507 copper ion binding(GO:0005507)
0.1 13.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 34.7 GO:0008134 transcription factor binding(GO:0008134)
0.1 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 11.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.8 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.7 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.1 3.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 22.8 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.4 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.6 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.0 0.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 8.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 2.7 GO:0044325 ion channel binding(GO:0044325)
0.0 3.5 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 43.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.5 29.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.4 38.7 PID ARF 3PATHWAY Arf1 pathway
1.1 38.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.0 6.8 PID AURORA A PATHWAY Aurora A signaling
0.9 20.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.7 58.0 PID LKB1 PATHWAY LKB1 signaling events
0.6 4.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 50.4 SIG CHEMOTAXIS Genes related to chemotaxis
0.6 10.5 ST GAQ PATHWAY G alpha q Pathway
0.5 13.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 8.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 20.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 2.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4 23.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.4 9.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 7.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 8.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 12.9 PID ALK1 PATHWAY ALK1 signaling events
0.3 13.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 6.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 5.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 3.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 20.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 11.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 7.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 10.3 PID AP1 PATHWAY AP-1 transcription factor network
0.2 6.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.2 PID IGF1 PATHWAY IGF1 pathway
0.1 7.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 8.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 5.5 PID INSULIN PATHWAY Insulin Pathway
0.1 7.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 5.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 31.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
2.6 87.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.7 28.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.7 26.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
1.6 124.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.6 32.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.5 36.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.5 5.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.5 42.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
1.4 27.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.2 26.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.1 14.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.1 22.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.1 14.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.0 19.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.9 18.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.9 17.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.9 42.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.8 10.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 36.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.7 13.6 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.7 11.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.7 19.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.7 22.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6 4.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.6 33.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5 12.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.5 26.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.5 8.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 22.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 6.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 15.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.5 39.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 4.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 10.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 6.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 8.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.4 2.8 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.4 5.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 9.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 7.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 4.5 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.3 9.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 16.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 7.9 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.3 15.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 2.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 3.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 9.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 5.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 11.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 41.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.3 62.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 7.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.3 11.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 4.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 3.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 13.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 7.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 50.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 15.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 2.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 5.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 3.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 5.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 12.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 6.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 8.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 0.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 2.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 6.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 3.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 20.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 11.0 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 5.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 4.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 18.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 16.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 5.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 3.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 3.7 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 4.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 1.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 6.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 4.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events