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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Evx2

Z-value: 0.79

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Transcription factors associated with Evx2

Gene Symbol Gene ID Gene Info
Evx2
ENSMUSG00000001815.16 Evx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Evx2mm39_v1_chr2_-_74489763_744899010.103.8e-01Click!

Activity profile of Evx2 motif

Sorted Z-values of Evx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Evx2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_69415741 7.65 ENSMUST00000103354.3
Igkv4-59
immunoglobulin kappa variable 4-59
chr6_-_69394425 5.68 ENSMUST00000199160.2
Igkv4-61
immunoglobulin kappa chain variable 4-61
chr6_-_68887922 5.12 ENSMUST00000103337.3
Igkv4-86
immunoglobulin kappa variable 4-86
chr6_-_69282389 5.01 ENSMUST00000103350.3
Igkv4-68
immunoglobulin kappa variable 4-68
chr6_-_69553484 4.92 ENSMUST00000103357.4
Igkv4-57
immunoglobulin kappa variable 4-57
chr6_-_69245427 4.84 ENSMUST00000103348.3
Igkv4-70
immunoglobulin kappa chain variable 4-70
chr13_+_51799268 4.82 ENSMUST00000075853.6
Cks2
CDC28 protein kinase regulatory subunit 2
chr5_-_65090893 4.67 ENSMUST00000197315.5
Tlr1
toll-like receptor 1
chr6_-_68994064 4.67 ENSMUST00000103341.4
Igkv4-80
immunoglobulin kappa variable 4-80
chr6_-_69204417 4.40 ENSMUST00000103346.3
Igkv4-72
immunoglobulin kappa chain variable 4-72
chr6_-_69162381 4.32 ENSMUST00000103344.3
Igkv4-74
immunoglobulin kappa variable 4-74
chr6_-_68887957 4.31 ENSMUST00000200454.2
Igkv4-86
immunoglobulin kappa variable 4-86
chr2_-_168608949 3.98 ENSMUST00000075044.10
Sall4
spalt like transcription factor 4
chr4_-_131802561 3.97 ENSMUST00000105970.8
ENSMUST00000105975.8
Epb41
erythrocyte membrane protein band 4.1
chr10_-_128361731 3.73 ENSMUST00000026427.8
Esyt1
extended synaptotagmin-like protein 1
chr6_-_68968278 3.69 ENSMUST00000197966.2
Igkv4-81
immunoglobulin kappa variable 4-81
chr6_-_69355456 3.68 ENSMUST00000196595.2
Igkv4-63
immunoglobulin kappa variable 4-63
chr4_-_131802606 3.65 ENSMUST00000146021.8
Epb41
erythrocyte membrane protein band 4.1
chr6_+_41928559 3.15 ENSMUST00000031898.5
Sval1
seminal vesicle antigen-like 1
chr1_+_36800874 2.94 ENSMUST00000027291.7
Zap70
zeta-chain (TCR) associated protein kinase
chr7_-_48493388 2.88 ENSMUST00000167786.4
Csrp3
cysteine and glycine-rich protein 3
chr2_-_168609110 2.88 ENSMUST00000029061.12
ENSMUST00000103074.2
Sall4
spalt like transcription factor 4
chr17_+_88748139 2.87 ENSMUST00000112238.9
ENSMUST00000155640.2
Foxn2
forkhead box N2
chr3_-_15491482 2.79 ENSMUST00000099201.9
ENSMUST00000194144.3
ENSMUST00000192700.3
Sirpb1a
signal-regulatory protein beta 1A
chr6_-_69678271 2.75 ENSMUST00000103363.2
Igkv4-50
immunoglobulin kappa variable 4-50
chr14_-_59602882 2.70 ENSMUST00000160425.8
ENSMUST00000095157.11
Phf11d
PHD finger protein 11D
chr6_-_68784692 2.56 ENSMUST00000103334.4
Igkv4-90
immunoglobulin kappa chain variable 4-90
chr11_+_116734104 2.41 ENSMUST00000106370.10
Mettl23
methyltransferase like 23
chr2_-_154916367 2.39 ENSMUST00000137242.2
ENSMUST00000054607.16
Ahcy
S-adenosylhomocysteine hydrolase
chr15_-_9529898 2.38 ENSMUST00000228782.2
ENSMUST00000003981.6
Il7r
interleukin 7 receptor
chr2_-_27365633 2.36 ENSMUST00000138693.8
ENSMUST00000113941.9
ENSMUST00000077737.13
Brd3
bromodomain containing 3
chr6_-_69020489 2.31 ENSMUST00000103342.4
Igkv4-79
immunoglobulin kappa variable 4-79
chr16_+_91184661 2.31 ENSMUST00000139503.2
Ifnar2
interferon (alpha and beta) receptor 2
chr14_+_62529924 2.30 ENSMUST00000166879.8
Rnaseh2b
ribonuclease H2, subunit B
chr10_-_80537805 2.28 ENSMUST00000218090.2
Mob3a
MOB kinase activator 3A
chr11_-_65160810 2.27 ENSMUST00000108695.9
Myocd
myocardin
chr14_+_19801333 2.27 ENSMUST00000022340.5
Nid2
nidogen 2
chr11_-_65160767 2.23 ENSMUST00000102635.10
Myocd
myocardin
chr14_-_59602859 2.13 ENSMUST00000161031.2
Phf11d
PHD finger protein 11D
chr6_-_69261303 2.12 ENSMUST00000103349.2
Igkv4-69
immunoglobulin kappa variable 4-69
chr10_+_26648473 2.04 ENSMUST00000039557.9
Arhgap18
Rho GTPase activating protein 18
chrX_-_56384089 2.02 ENSMUST00000033468.11
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr3_-_15640045 1.98 ENSMUST00000192382.6
ENSMUST00000195778.3
ENSMUST00000091319.7
Sirpb1b
signal-regulatory protein beta 1B
chr5_-_90788323 1.97 ENSMUST00000202784.4
ENSMUST00000031317.10
ENSMUST00000201370.2
Rassf6
Ras association (RalGDS/AF-6) domain family member 6
chr2_+_118877610 1.90 ENSMUST00000153300.8
ENSMUST00000028799.12
Knl1
kinetochore scaffold 1
chr1_-_171854818 1.82 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
Vangl2
VANGL planar cell polarity 2
chr11_+_60428788 1.81 ENSMUST00000044250.4
Alkbh5
alkB homolog 5, RNA demethylase
chr18_-_64688271 1.80 ENSMUST00000235459.2
Atp8b1
ATPase, class I, type 8B, member 1
chr9_-_85631361 1.78 ENSMUST00000039213.15
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_-_69377328 1.74 ENSMUST00000198345.2
Igkv4-62
immunoglobulin kappa variable 4-62
chr10_-_80537652 1.70 ENSMUST00000003438.11
Mob3a
MOB kinase activator 3A
chr9_-_107556823 1.65 ENSMUST00000010205.9
Gnat1
guanine nucleotide binding protein, alpha transducing 1
chr4_-_132073048 1.58 ENSMUST00000084250.11
Rcc1
regulator of chromosome condensation 1
chr12_-_55061117 1.50 ENSMUST00000172875.8
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr19_+_5138562 1.33 ENSMUST00000238093.2
ENSMUST00000025811.6
ENSMUST00000237025.2
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr10_+_39488930 1.32 ENSMUST00000019987.7
Traf3ip2
TRAF3 interacting protein 2
chr8_-_35962641 1.28 ENSMUST00000033927.8
Eri1
exoribonuclease 1
chr2_-_150097511 1.28 ENSMUST00000063463.6
Gm21994
predicted gene 21994
chr5_-_116162415 1.27 ENSMUST00000031486.14
ENSMUST00000111999.8
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr19_+_47056161 1.24 ENSMUST00000026027.7
Taf5
TATA-box binding protein associated factor 5
chr5_-_90788460 1.19 ENSMUST00000202704.4
Rassf6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_116627635 0.94 ENSMUST00000204555.2
Depp1
DEPP1 autophagy regulator
chr6_-_51443602 0.92 ENSMUST00000203253.2
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_-_111820618 0.82 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
Olfr1309
olfactory receptor 1309
chr4_-_52856572 0.80 ENSMUST00000051520.3
Olfr273
olfactory receptor 273
chr3_+_94745009 0.78 ENSMUST00000107266.8
ENSMUST00000042402.12
ENSMUST00000107269.2
Pogz
pogo transposable element with ZNF domain
chr4_-_132072988 0.77 ENSMUST00000030726.13
Rcc1
regulator of chromosome condensation 1
chr14_+_53521353 0.76 ENSMUST00000103625.3
Trav3n-3
T cell receptor alpha variable 3N-3
chr17_-_37430949 0.72 ENSMUST00000214994.2
ENSMUST00000216341.2
Olfr92
olfactory receptor 92
chr2_+_167345009 0.65 ENSMUST00000078050.7
Rnf114
ring finger protein 114
chr10_-_128425519 0.65 ENSMUST00000082059.7
Erbb3
erb-b2 receptor tyrosine kinase 3
chr10_+_70010839 0.55 ENSMUST00000156001.8
ENSMUST00000135607.2
Ccdc6
coiled-coil domain containing 6
chr3_+_94744844 0.54 ENSMUST00000107270.9
Pogz
pogo transposable element with ZNF domain
chr8_-_31658775 0.52 ENSMUST00000033983.6
Mak16
MAK16 homolog
chr19_-_13828056 0.49 ENSMUST00000208493.3
Olfr1501
olfactory receptor 1501
chr13_+_38388904 0.46 ENSMUST00000091641.13
ENSMUST00000178564.2
Snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr6_+_122603369 0.45 ENSMUST00000049644.9
Dppa3
developmental pluripotency-associated 3
chr8_+_93581946 0.42 ENSMUST00000046290.3
ENSMUST00000210099.2
Lpcat2
lysophosphatidylcholine acyltransferase 2
chr11_+_58468556 0.40 ENSMUST00000203418.4
Olfr325
olfactory receptor 325
chr10_-_128885867 0.39 ENSMUST00000216460.2
Olfr765
olfactory receptor 765
chr5_+_33493529 0.38 ENSMUST00000202113.2
Maea
macrophage erythroblast attacher
chr19_-_41921676 0.37 ENSMUST00000075280.12
ENSMUST00000112123.4
Exosc1
exosome component 1
chr14_+_73411249 0.36 ENSMUST00000166875.2
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_84545504 0.36 ENSMUST00000035840.6
Zdhhc5
zinc finger, DHHC domain containing 5
chr4_+_115747862 0.36 ENSMUST00000132221.3
ENSMUST00000165938.2
6430628N08Rik
RIKEN cDNA 6430628N08 gene
chr1_-_92423800 0.35 ENSMUST00000204766.2
ENSMUST00000204009.3
Olfr1415
olfactory receptor 1415
chr18_-_88945571 0.34 ENSMUST00000147313.2
Socs6
suppressor of cytokine signaling 6
chr19_-_13827773 0.34 ENSMUST00000215350.2
Olfr1501
olfactory receptor 1501
chrX_-_74207359 0.33 ENSMUST00000101433.9
Smim9
small integral membrane protein 9
chr6_-_69377081 0.32 ENSMUST00000177795.2
Igkv4-62
immunoglobulin kappa variable 4-62
chr3_-_130503041 0.30 ENSMUST00000043937.9
Ostc
oligosaccharyltransferase complex subunit (non-catalytic)
chr8_+_14938022 0.29 ENSMUST00000123990.2
ENSMUST00000027554.8
Cln8
CLN8 transmembrane ER and ERGIC protein
chr14_+_65612788 0.27 ENSMUST00000224687.2
Zfp395
zinc finger protein 395
chr7_+_12700030 0.27 ENSMUST00000210619.2
Zfp324
zinc finger protein 324
chr3_+_121085471 0.18 ENSMUST00000199554.2
Alg14
asparagine-linked glycosylation 14
chr7_-_86016045 0.16 ENSMUST00000213255.2
ENSMUST00000216700.2
ENSMUST00000213869.2
Olfr305
olfactory receptor 305
chr16_+_3648742 0.15 ENSMUST00000214238.2
ENSMUST00000214590.2
Olfr15
olfactory receptor 15
chr2_-_86257093 0.13 ENSMUST00000217481.2
Olfr1062
olfactory receptor 1062
chr11_-_61157986 0.12 ENSMUST00000066277.10
ENSMUST00000074127.14
ENSMUST00000108715.3
Aldh3a2
aldehyde dehydrogenase family 3, subfamily A2
chr1_-_144427302 0.11 ENSMUST00000184189.3
Rgs21
regulator of G-protein signalling 21
chr4_-_42661893 0.11 ENSMUST00000108006.4
Il11ra2
interleukin 11 receptor, alpha chain 2
chrX_+_57075981 0.11 ENSMUST00000088627.11
Zic3
zinc finger protein of the cerebellum 3
chr3_+_121085500 0.08 ENSMUST00000198341.2
Alg14
asparagine-linked glycosylation 14
chr17_+_38143840 0.04 ENSMUST00000213857.2
Olfr125
olfactory receptor 125
chr11_-_6217718 0.04 ENSMUST00000004507.11
ENSMUST00000151446.2
Ddx56
DEAD box helicase 56

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495)
1.5 4.5 GO:1900239 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
1.0 2.9 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.6 1.8 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.6 2.4 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.5 2.9 GO:0043366 beta selection(GO:0043366)
0.4 7.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 2.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 0.9 GO:1990428 miRNA transport(GO:1990428)
0.3 1.8 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 1.6 GO:0051342 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.3 71.4 GO:0002377 immunoglobulin production(GO:0002377)
0.3 6.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.8 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 1.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.4 GO:0048822 enucleate erythrocyte development(GO:0048822)
0.1 0.5 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 1.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 2.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 2.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 4.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 2.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 2.8 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 2.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.6 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.6 1.8 GO:0060187 cell pole(GO:0060187)
0.4 2.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.5 GO:0008623 CHRAC(GO:0008623)
0.2 3.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 7.6 GO:0099738 cell cortex region(GO:0099738)
0.1 2.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 4.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 6.4 GO:0000792 heterochromatin(GO:0000792)
0.0 0.5 GO:0001940 male pronucleus(GO:0001940)
0.0 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 65.6 GO:0005615 extracellular space(GO:0005615)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.0 4.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.3 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0042497 triacyl lipopeptide binding(GO:0042497)
0.8 4.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 2.3 GO:0004905 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.4 2.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 2.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 2.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 1.8 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 7.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 4.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 2.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 2.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 4.6 GO:0003823 antigen binding(GO:0003823)
0.0 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 4.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 6.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 4.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 2.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.6 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling