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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Figla

Z-value: 1.01

Motif logo

Transcription factors associated with Figla

Gene Symbol Gene ID Gene Info
ENSMUSG00000030001.5 Figla

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Figlamm39_v1_chr6_+_85994173_859942140.353.0e-03Click!

Activity profile of Figla motif

Sorted Z-values of Figla motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Figla

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_152626273 6.06 ENSMUST00000068875.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr4_-_128154709 5.92 ENSMUST00000053830.5
high-mobility group box 4
chr11_-_99501015 5.87 ENSMUST00000076478.2
predicted gene 11937
chr6_-_124519240 5.80 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr11_-_99519057 5.78 ENSMUST00000081007.7
keratin associated protein 4-1
chr14_-_20231871 5.66 ENSMUST00000024011.10
potassium channel, subfamily K, member 5
chrX_+_100427331 5.52 ENSMUST00000119190.2
gap junction protein, beta 1
chr11_+_99755302 5.39 ENSMUST00000092694.4
predicted gene 11559
chr8_+_106032205 5.20 ENSMUST00000109375.4
ENSMUST00000212033.2
engulfment and cell motility 3
chr2_+_122479770 5.13 ENSMUST00000047498.15
ENSMUST00000110512.4
expressed sequence AA467197
chr6_-_3494587 5.03 ENSMUST00000049985.15
HEPACAM family member 2
chr10_+_127702326 5.03 ENSMUST00000092058.4
RDH16 family member 2
chr11_-_120441952 4.95 ENSMUST00000026121.3
protein phosphatase 1, regulatory subunit 27
chr11_+_115714853 4.86 ENSMUST00000103032.11
ENSMUST00000133250.8
ENSMUST00000177736.8
LLGL2 scribble cell polarity complex component
chr11_+_96820220 4.80 ENSMUST00000062172.6
proline rich 15-like
chr7_+_30673212 4.70 ENSMUST00000129773.2
family with sequence similarity 187, member B
chr2_-_91025492 4.61 ENSMUST00000111354.2
nuclear receptor subfamily 1, group H, member 3
chr11_-_5900019 4.54 ENSMUST00000102920.4
glucokinase
chr15_+_88703786 4.45 ENSMUST00000024042.5
cysteine-rich with EGF-like domains 2
chr16_-_10614679 4.36 ENSMUST00000023144.6
protamine 1
chr9_-_108443916 4.33 ENSMUST00000194381.2
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr7_+_27770655 4.30 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr6_-_135224881 4.25 ENSMUST00000087729.12
germ cell associated 1
chr2_-_91025208 4.25 ENSMUST00000111355.8
nuclear receptor subfamily 1, group H, member 3
chr4_-_49681954 4.24 ENSMUST00000029991.3
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
chr7_-_30672824 4.23 ENSMUST00000147431.2
ENSMUST00000098553.11
ENSMUST00000108116.10
lipolysis stimulated lipoprotein receptor
chr11_+_96820091 4.22 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr16_+_4825216 4.18 ENSMUST00000185147.8
small integral membrane protein 22
chr8_+_55053809 4.16 ENSMUST00000033917.7
spermatogenesis associated 4
chr8_-_71834543 4.14 ENSMUST00000002466.9
nuclear receptor subfamily 2, group F, member 6
chr7_-_30672747 4.13 ENSMUST00000205961.2
lipolysis stimulated lipoprotein receptor
chr11_-_67812960 4.09 ENSMUST00000021288.10
ENSMUST00000108677.2
ubiquitin specific peptidase 43
chr5_-_66238313 4.06 ENSMUST00000202700.4
ENSMUST00000094757.9
ENSMUST00000113724.6
RNA binding motif protein 47
chr16_+_14523696 4.06 ENSMUST00000023356.8
snail family zinc finger 2
chr17_+_47747657 4.00 ENSMUST00000150819.3
expressed sequence AI661453
chr9_-_50657800 4.00 ENSMUST00000239417.2
ENSMUST00000034564.4
RIKEN cDNA 2310030G06 gene
chr7_-_30672889 3.99 ENSMUST00000001279.15
lipolysis stimulated lipoprotein receptor
chr2_+_164611812 3.94 ENSMUST00000088248.13
ENSMUST00000001439.7
ubiquitin-conjugating enzyme E2C
chr1_+_171265103 3.90 ENSMUST00000043839.5
F11 receptor
chr12_-_40088024 3.83 ENSMUST00000101472.4
ADP-ribosylation factor-like 4A
chr11_-_99482165 3.82 ENSMUST00000104930.2
keratin associated protein 1-3
chr2_-_91025380 3.81 ENSMUST00000111356.8
nuclear receptor subfamily 1, group H, member 3
chr7_+_34818709 3.81 ENSMUST00000205391.2
ENSMUST00000042985.11
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_-_52225763 3.80 ENSMUST00000238288.2
ENSMUST00000238749.2
nebulin
chr6_+_29694181 3.78 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr11_-_99494134 3.73 ENSMUST00000072306.4
predicted gene 11938
chr11_+_99805555 3.69 ENSMUST00000105053.2
predicted gene 11565
chr10_+_75729237 3.64 ENSMUST00000009236.6
ENSMUST00000217811.2
Der1-like domain family, member 3
chr17_-_32639936 3.63 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr11_+_45871135 3.60 ENSMUST00000049038.4
SRY (sex determining region Y)-box 30
chr2_+_153334710 3.52 ENSMUST00000109783.2
RIKEN cDNA 4930404H24 gene
chr7_-_24145107 3.42 ENSMUST00000205776.2
immunity-related GTPase family, cinema 1
chr7_+_126811831 3.27 ENSMUST00000127710.3
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_117700479 3.25 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
synaptogyrin 2
predicted gene 20708
chr19_-_38113056 3.22 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr16_+_4825170 3.14 ENSMUST00000178155.9
small integral membrane protein 22
chr17_-_43813664 3.10 ENSMUST00000024707.9
ENSMUST00000117137.8
meprin 1 alpha
chr10_+_97528915 3.07 ENSMUST00000060703.6
coiled-coil glutamate-rich protein 1
chr11_+_101875095 3.04 ENSMUST00000176722.8
ENSMUST00000175972.2
CFAP97 domain containing 1
chr6_-_120271520 3.03 ENSMUST00000057283.8
ENSMUST00000212457.2
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr17_+_57369231 3.01 ENSMUST00000097299.10
ENSMUST00000169543.8
ENSMUST00000163763.2
crumbs family member 3
chr9_-_63509747 3.01 ENSMUST00000080527.12
ENSMUST00000042322.11
IQ motif containing H
chr12_-_40087393 3.00 ENSMUST00000146905.2
ADP-ribosylation factor-like 4A
chr6_-_52194440 2.96 ENSMUST00000048715.9
homeobox A7
chr10_+_108168520 2.96 ENSMUST00000218332.2
PRKC, apoptosis, WT1, regulator
chr11_-_82761954 2.93 ENSMUST00000108173.10
ENSMUST00000071152.14
ring finger and FYVE like domain containing protein
chr3_+_106393348 2.92 ENSMUST00000183271.2
DENN/MADD domain containing 2D
chr2_-_92201342 2.92 ENSMUST00000176810.8
ENSMUST00000090582.11
ENSMUST00000068586.13
LARGE xylosyl- and glucuronyltransferase 2
chr9_-_63509699 2.91 ENSMUST00000171243.2
ENSMUST00000163982.8
ENSMUST00000163624.8
IQ motif containing H
chr17_+_47747540 2.91 ENSMUST00000037701.13
expressed sequence AI661453
chr11_-_68817875 2.89 ENSMUST00000038932.14
ENSMUST00000125134.2
outer dense fiber of sperm tails 4
chr15_+_99615396 2.88 ENSMUST00000023760.13
ENSMUST00000162194.2
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr15_-_89263790 2.88 ENSMUST00000238996.2
outer dense fiber of sperm tails 3B
chr16_+_4825146 2.83 ENSMUST00000184439.8
small integral membrane protein 22
chr10_+_127595639 2.75 ENSMUST00000128247.2
RDH16 family member 1
chr2_+_167922924 2.74 ENSMUST00000052125.7
par-6 family cell polarity regulator beta
chr5_+_20112771 2.69 ENSMUST00000200443.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_108444561 2.64 ENSMUST00000074208.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr9_-_114673158 2.63 ENSMUST00000047013.4
CKLF-like MARVEL transmembrane domain containing 8
chr3_+_51324022 2.61 ENSMUST00000192419.6
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_69576363 2.59 ENSMUST00000018896.14
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_100036792 2.58 ENSMUST00000007317.8
keratin 19
chr1_+_59555423 2.58 ENSMUST00000114243.8
predicted gene 973
chr11_+_53661251 2.57 ENSMUST00000138913.8
ENSMUST00000123376.8
ENSMUST00000019043.13
ENSMUST00000133291.3
interferon regulatory factor 1
chr2_-_168607166 2.56 ENSMUST00000137536.2
spalt like transcription factor 4
chr10_-_21036792 2.53 ENSMUST00000188495.8
myeloblastosis oncogene
chr15_-_89263128 2.52 ENSMUST00000227834.2
outer dense fiber of sperm tails 3B
chr9_+_107424488 2.51 ENSMUST00000010188.9
zinc finger, MYND domain containing 10
chr16_+_4653271 2.44 ENSMUST00000100211.11
RIKEN cDNA 4930562C15 gene
chr11_-_99511257 2.44 ENSMUST00000073853.3
predicted gene 11562
chr12_+_78795647 2.42 ENSMUST00000219667.2
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr6_+_54303837 2.37 ENSMUST00000059138.6
proline rich 15
chr8_+_123148759 2.32 ENSMUST00000050963.4
interleukin 17C
chr13_-_100922910 2.28 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr17_-_56607286 2.26 ENSMUST00000097303.3
arrestin domain containing 5
chr15_-_89263448 2.22 ENSMUST00000049968.9
outer dense fiber of sperm tails 3B
chrX_+_21581135 2.20 ENSMUST00000033414.8
solute carrier family 6 (neurotransmitter transporter), member 14
chr15_+_25622611 2.19 ENSMUST00000110457.8
ENSMUST00000137601.8
myosin X
chr3_-_20329823 2.19 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr7_+_18828519 2.18 ENSMUST00000049454.6
sine oculis-related homeobox 5
chr5_-_28415020 2.18 ENSMUST00000118882.2
canopy FGF signaling regulator 1
chr1_-_156168522 2.17 ENSMUST00000212747.2
axonemal dynein light chain domain containing 1
chr11_+_69983531 2.16 ENSMUST00000124721.2
asialoglycoprotein receptor 2
chr14_-_21798694 2.14 ENSMUST00000183943.2
dual specificity phosphatase 13
chr6_-_52194414 2.14 ENSMUST00000140316.2
homeobox A7
chrX_-_52203405 2.10 ENSMUST00000114843.9
placental specific protein 1
chr4_+_106418224 2.07 ENSMUST00000047973.4
24-dehydrocholesterol reductase
chr6_+_39358036 2.06 ENSMUST00000031986.5
RAB19, member RAS oncogene family
chr11_+_69983459 2.05 ENSMUST00000102572.8
asialoglycoprotein receptor 2
chr9_-_50679408 2.03 ENSMUST00000177546.8
ENSMUST00000176238.2
RIKEN cDNA 1110032A03 gene
chr14_-_21798678 2.02 ENSMUST00000075040.9
dual specificity phosphatase 13
chr10_-_21036824 2.01 ENSMUST00000020158.9
myeloblastosis oncogene
chr19_+_36325683 2.01 ENSMUST00000225920.2
polycomb group ring finger 5
chr9_+_107445101 1.99 ENSMUST00000192887.6
ENSMUST00000195752.6
hyaluronoglucosaminidase 2
chr10_+_50770836 1.99 ENSMUST00000219436.2
single-minded family bHLH transcription factor 1
chr14_-_20319242 1.95 ENSMUST00000024155.9
potassium channel, subfamily K, member 16
chr2_+_152753231 1.95 ENSMUST00000028970.8
myosin, light polypeptide kinase 2, skeletal muscle
chr12_+_31315227 1.94 ENSMUST00000169088.8
laminin B1
chr5_-_30401416 1.91 ENSMUST00000125367.4
adhesion G protein-coupled receptor F3
chr3_+_40663285 1.90 ENSMUST00000091184.9
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr1_-_192880260 1.89 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr11_-_48836975 1.89 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr9_-_97252011 1.87 ENSMUST00000035026.5
tripartite motif-containing 42
chr10_-_63257568 1.86 ENSMUST00000054760.6
predicted gene 7075
chr11_-_99742434 1.85 ENSMUST00000107437.2
keratin associated protein 4-16
chr3_+_65435825 1.85 ENSMUST00000047906.10
TCDD-inducible poly(ADP-ribose) polymerase
chr17_-_56607250 1.84 ENSMUST00000233911.2
arrestin domain containing 5
chr9_+_51027300 1.84 ENSMUST00000114431.4
ENSMUST00000213117.2
BTG anti-proliferation factor 4
chr11_+_69983479 1.83 ENSMUST00000143772.8
asialoglycoprotein receptor 2
chr8_+_120121612 1.81 ENSMUST00000098367.5
malonyl-CoA decarboxylase
chr14_-_47426863 1.81 ENSMUST00000089959.7
GTP cyclohydrolase 1
chr5_-_28415166 1.81 ENSMUST00000117098.2
canopy FGF signaling regulator 1
chr9_-_44253630 1.80 ENSMUST00000097558.5
hydroxymethylbilane synthase
chr8_+_93084253 1.79 ENSMUST00000210246.2
ENSMUST00000034184.12
Iroquois homeobox 5
chr7_+_79675727 1.75 ENSMUST00000049680.10
zinc finger protein 710
chr11_+_72326391 1.74 ENSMUST00000100903.3
gamma-glutamyltransferase 6
chr5_+_123887759 1.74 ENSMUST00000031366.12
kinetochore associated 1
chr3_+_102981326 1.73 ENSMUST00000090715.13
ENSMUST00000155034.6
adenosine monophosphate deaminase 1
chr7_+_48993197 1.73 ENSMUST00000207743.2
neuron navigator 2
chr17_+_57369490 1.72 ENSMUST00000163628.2
crumbs family member 3
chr13_+_113346193 1.71 ENSMUST00000038144.9
endothelial cell-specific molecule 1
chr2_-_52225146 1.70 ENSMUST00000075301.10
nebulin
chr17_+_35413415 1.70 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr4_+_122889407 1.69 ENSMUST00000144998.2
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
chr5_-_138170077 1.68 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr12_+_31315270 1.65 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chr7_+_27879650 1.64 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chrX_-_73325318 1.64 ENSMUST00000239458.2
ENSMUST00000019232.10
deoxyribonuclease 1-like 1
chr8_+_46338557 1.63 ENSMUST00000210422.2
PDZ and LIM domain 3
chr1_+_165288606 1.63 ENSMUST00000027853.6
mitochondrial pyruvate carrier 2
chr9_-_44253588 1.63 ENSMUST00000215091.2
hydroxymethylbilane synthase
chr4_-_137157824 1.63 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr11_-_99505668 1.62 ENSMUST00000074926.6
keratin associated protein 2-4
chr11_-_99920694 1.58 ENSMUST00000073890.4
keratin 33B
chr15_-_65784103 1.56 ENSMUST00000079776.14
otoconin 90
chr9_+_43978369 1.56 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chr3_+_102981352 1.55 ENSMUST00000176440.2
adenosine monophosphate deaminase 1
chr13_+_21364330 1.55 ENSMUST00000223065.2
tripartite motif-containing 27
chr4_+_107825529 1.53 ENSMUST00000106713.5
ENSMUST00000238795.2
solute carrier family 1 (glutamate transporter), member 7
chr1_-_155617773 1.53 ENSMUST00000027740.14
LIM homeobox protein 4
chr5_+_146168020 1.52 ENSMUST00000161181.8
ENSMUST00000161652.8
ENSMUST00000031640.15
ENSMUST00000159467.2
cyclin-dependent kinase 8
chr10_-_75768302 1.51 ENSMUST00000120281.8
ENSMUST00000000924.13
matrix metallopeptidase 11
chr11_+_53324126 1.51 ENSMUST00000018382.7
growth differentiation factor 9
chr15_+_59520199 1.50 ENSMUST00000067543.8
tribbles pseudokinase 1
chr9_+_57468217 1.49 ENSMUST00000045791.11
ENSMUST00000216986.2
secretory carrier membrane protein 2
chr6_-_93889483 1.48 ENSMUST00000205116.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr8_-_123349473 1.47 ENSMUST00000212966.2
ENSMUST00000093059.3
poly(A)binding protein nuclear 1-like
chr5_+_75236250 1.47 ENSMUST00000040477.4
ENSMUST00000160104.3
GS homeobox 2
chr4_+_116414855 1.46 ENSMUST00000030460.15
GC-rich promoter binding protein 1-like 1
chr8_+_70953766 1.45 ENSMUST00000127983.2
cytokine receptor-like factor 1
chr14_-_104705420 1.43 ENSMUST00000053016.10
POU domain, class 4, transcription factor 1
chr4_+_150233362 1.42 ENSMUST00000059893.8
solute carrier family 2 (facilitated glucose transporter), member 7
chr6_-_125357756 1.41 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr7_+_78564062 1.41 ENSMUST00000205981.2
interferon-stimulated protein
chr14_-_31552335 1.41 ENSMUST00000228037.2
ankyrin repeat domain 28
chr7_+_78563964 1.41 ENSMUST00000120331.4
interferon-stimulated protein
chr3_-_32546380 1.40 ENSMUST00000164954.3
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr14_+_54406112 1.39 ENSMUST00000103694.3
ENSMUST00000199452.2
T cell receptor alpha joining 49
chr19_-_11243530 1.38 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr10_-_128579879 1.38 ENSMUST00000026414.9
diacylglycerol kinase, alpha
chr13_-_95615229 1.37 ENSMUST00000022186.5
S100 calcium binding protein, zeta
chr15_+_59520493 1.36 ENSMUST00000118228.2
tribbles pseudokinase 1
chr4_-_137137088 1.33 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr15_-_89263466 1.32 ENSMUST00000228111.2
outer dense fiber of sperm tails 3B
chr4_-_126362372 1.30 ENSMUST00000097888.10
ENSMUST00000239399.2
argonaute RISC catalytic subunit 1
chr15_-_65784246 1.30 ENSMUST00000060522.11
otoconin 90
chr7_-_142233270 1.29 ENSMUST00000162317.2
ENSMUST00000125933.2
ENSMUST00000105931.8
ENSMUST00000105930.8
ENSMUST00000105933.8
ENSMUST00000105932.2
ENSMUST00000000220.3
insulin II
chr7_-_80051455 1.29 ENSMUST00000120753.3
furin (paired basic amino acid cleaving enzyme)
chr2_-_110144869 1.28 ENSMUST00000133608.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr2_-_122441719 1.27 ENSMUST00000028624.9
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr13_+_47347301 1.26 ENSMUST00000110111.4
ring finger protein 144B
chr8_-_48443525 1.26 ENSMUST00000057561.9
WW, C2 and coiled-coil domain containing 2
chr9_+_107431776 1.24 ENSMUST00000010211.7
Ras association (RalGDS/AF-6) domain family member 1
chr7_+_44866635 1.22 ENSMUST00000097216.5
ENSMUST00000209343.2
ENSMUST00000209678.2
TEA domain family member 2
chr11_+_43419586 1.21 ENSMUST00000050574.7
cyclin J-like
chr11_-_99932373 1.20 ENSMUST00000056362.3
keratin 34
chr2_-_28453374 1.19 ENSMUST00000028161.6
carboxyl ester lipase
chr15_-_78290038 1.18 ENSMUST00000058659.9
thiosulfate sulfurtransferase, mitochondrial
chr2_+_132688558 1.17 ENSMUST00000028835.13
ENSMUST00000110122.10
cardiolipin synthase 1
chr8_-_44080313 1.16 ENSMUST00000056023.5
a disintegrin and metallopeptidase domain 34 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
3.2 12.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.4 4.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.2 4.9 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
1.1 3.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.0 3.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) positive regulation of hindgut contraction(GO:0060450) regulation of relaxation of smooth muscle(GO:1901080) positive regulation of relaxation of smooth muscle(GO:1901082)
1.0 2.9 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.0 2.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.9 4.5 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.9 3.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 2.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.7 2.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 3.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.6 2.6 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.6 3.6 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.6 1.8 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.6 2.3 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.5 1.6 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.5 2.0 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.5 3.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.5 1.9 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.5 2.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 5.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.5 1.8 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.4 5.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 2.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.4 1.3 GO:1990535 neuron projection maintenance(GO:1990535)
0.4 4.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.4 1.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 5.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.4 1.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.4 1.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.4 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 1.5 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.4 7.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 1.4 GO:0048880 proprioception(GO:0019230) sensory system development(GO:0048880)
0.3 2.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 4.3 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.3 3.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 3.3 GO:0032264 IMP salvage(GO:0032264)
0.3 4.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.3 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 4.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 2.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 4.2 GO:0007320 insemination(GO:0007320)
0.3 2.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 1.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 1.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 1.7 GO:0021564 vagus nerve development(GO:0021564)
0.2 2.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 1.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 2.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.7 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.2 0.9 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 0.7 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 2.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 3.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 4.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2 0.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 2.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 2.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 0.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2 2.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 8.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 2.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 0.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.7 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.2 1.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.2 1.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 2.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 3.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.9 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 2.4 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 1.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 2.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.0 GO:0030035 microspike assembly(GO:0030035)
0.1 2.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 4.4 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 8.0 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 1.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.3 GO:0048478 replication fork protection(GO:0048478)
0.1 1.5 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 2.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.1 GO:0031639 plasminogen activation(GO:0031639)
0.1 2.9 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 4.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.4 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 1.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.6 GO:1900040 regulation of interleukin-2 secretion(GO:1900040)
0.0 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 5.6 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.7 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 2.9 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 3.0 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 2.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.4 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 2.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 12.1 GO:0061689 tricellular tight junction(GO:0061689)
1.3 3.8 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.2 3.6 GO:0005607 laminin-2 complex(GO:0005607)
0.6 1.7 GO:1990423 RZZ complex(GO:1990423)
0.6 2.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.5 3.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 3.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 6.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 2.6 GO:1990357 terminal web(GO:1990357)
0.3 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 5.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 4.5 GO:0045180 basal cortex(GO:0045180)
0.2 2.6 GO:0031415 NatA complex(GO:0031415)
0.2 5.7 GO:0005922 connexon complex(GO:0005922)
0.2 2.9 GO:0001520 outer dense fiber(GO:0001520)
0.2 3.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.9 GO:0042555 MCM complex(GO:0042555)
0.1 4.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 4.4 GO:0000786 nucleosome(GO:0000786)
0.1 0.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:0035363 histone locus body(GO:0035363)
0.1 6.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 11.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 1.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0042588 zymogen granule(GO:0042588)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.2 GO:0030904 retromer complex(GO:0030904)
0.0 5.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 4.8 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 7.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.9 GO:0072562 blood microparticle(GO:0072562)
0.0 2.6 GO:0000792 heterochromatin(GO:0000792)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 7.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 2.9 GO:0010008 endosome membrane(GO:0010008)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 3.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 3.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.7 GO:0032810 sterol response element binding(GO:0032810)
1.1 3.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
1.1 3.2 GO:0034632 retinol transporter activity(GO:0034632)
1.0 2.9 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.9 4.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.6 3.6 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.6 1.7 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.6 2.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 4.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 2.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.5 12.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 4.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.5 4.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.4 2.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.4 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 7.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 0.3 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.3 3.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.3 5.7 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 3.8 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 1.8 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 1.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 3.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 5.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 6.1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 10.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.0 GO:0070404 NADH binding(GO:0070404)
0.1 1.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 2.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 4.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 2.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 3.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 4.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 4.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 2.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.2 GO:0042166 acetylcholine binding(GO:0042166)
0.1 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 6.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 2.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 11.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 4.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 2.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.3 GO:0002039 p53 binding(GO:0002039)
0.0 8.1 GO:0005125 cytokine activity(GO:0005125)
0.0 1.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 4.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 2.2 GO:0030507 spectrin binding(GO:0030507)
0.0 8.7 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 12.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 3.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 11.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 8.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 5.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 3.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 3.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 6.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.2 5.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 16.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 4.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import