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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxb1

Z-value: 0.78

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Transcription factors associated with Foxb1

Gene Symbol Gene ID Gene Info
Foxb1
ENSMUSG00000059246.5 Foxb1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxb1mm39_v1_chr9_-_69668204_696682220.094.4e-01Click!

Activity profile of Foxb1 motif

Sorted Z-values of Foxb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxb1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_7494108 7.22 ENSMUST00000193330.2
Pkia
protein kinase inhibitor, alpha
chr17_+_48037758 6.51 ENSMUST00000024782.12
ENSMUST00000144955.2
Pgc
progastricsin (pepsinogen C)
chr4_+_127066667 5.52 ENSMUST00000106094.9
Dlgap3
DLG associated protein 3
chr19_+_47217279 5.37 ENSMUST00000111807.5
Neurl1a
neuralized E3 ubiquitin protein ligase 1A
chr2_+_109522781 4.84 ENSMUST00000111050.10
Bdnf
brain derived neurotrophic factor
chr17_+_70829050 4.73 ENSMUST00000133717.9
ENSMUST00000148486.8
Dlgap1
DLG associated protein 1
chr7_-_141009264 4.38 ENSMUST00000164387.2
ENSMUST00000137488.2
ENSMUST00000084436.10
Cend1
cell cycle exit and neuronal differentiation 1
chr10_+_69761784 4.37 ENSMUST00000181974.8
ENSMUST00000182795.8
ENSMUST00000182437.8
Ank3
ankyrin 3, epithelial
chr5_+_66833434 4.29 ENSMUST00000031131.11
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr17_+_70829144 4.20 ENSMUST00000140728.8
Dlgap1
DLG associated protein 1
chr10_+_69761597 4.15 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
Ank3
ankyrin 3, epithelial
chr5_-_51725059 4.13 ENSMUST00000127135.3
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr8_-_62576140 3.87 ENSMUST00000034052.14
ENSMUST00000034054.9
Anxa10
annexin A10
chr18_+_69652837 3.85 ENSMUST00000201410.4
ENSMUST00000202937.4
Tcf4
transcription factor 4
chr18_+_69652550 3.74 ENSMUST00000201205.4
Tcf4
transcription factor 4
chr7_-_141009346 3.71 ENSMUST00000124444.2
Cend1
cell cycle exit and neuronal differentiation 1
chrX_+_40490005 3.64 ENSMUST00000115103.9
ENSMUST00000076349.12
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr18_+_38809771 3.54 ENSMUST00000134388.2
ENSMUST00000148850.8
9630014M24Rik
Arhgap26
RIKEN cDNA 9630014M24 gene
Rho GTPase activating protein 26
chr16_-_44153288 3.38 ENSMUST00000136381.8
Sidt1
SID1 transmembrane family, member 1
chr18_+_37085673 3.21 ENSMUST00000192512.6
ENSMUST00000192295.2
ENSMUST00000115661.5
Pcdha4
Gm42416
protocadherin alpha 4
predicted gene, 42416
chr16_-_44153498 3.20 ENSMUST00000047446.13
Sidt1
SID1 transmembrane family, member 1
chr8_+_94763826 3.14 ENSMUST00000109556.9
ENSMUST00000093301.9
ENSMUST00000060632.8
Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr12_-_84497718 3.10 ENSMUST00000085192.7
ENSMUST00000220491.2
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr10_-_49659355 2.97 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr18_-_25886750 2.88 ENSMUST00000224553.2
ENSMUST00000025117.14
Celf4
CUGBP, Elav-like family member 4
chr10_+_69761314 2.83 ENSMUST00000182692.8
ENSMUST00000092433.12
Ank3
ankyrin 3, epithelial
chr3_-_146487102 2.82 ENSMUST00000005164.12
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_-_144761806 2.81 ENSMUST00000208788.2
Smim38
small integral membrane protein 38
chr5_+_57879201 2.74 ENSMUST00000199310.2
Pcdh7
protocadherin 7
chr3_-_92922976 2.71 ENSMUST00000107301.2
ENSMUST00000029521.5
Crct1
cysteine-rich C-terminal 1
chr7_-_99994257 2.71 ENSMUST00000207634.2
Ppme1
protein phosphatase methylesterase 1
chr16_-_74208180 2.70 ENSMUST00000117200.8
Robo2
roundabout guidance receptor 2
chr5_+_102629240 2.69 ENSMUST00000073302.12
ENSMUST00000094559.9
Arhgap24
Rho GTPase activating protein 24
chr3_+_75982890 2.68 ENSMUST00000160261.8
Fstl5
follistatin-like 5
chr18_+_69652751 2.62 ENSMUST00000200966.4
Tcf4
transcription factor 4
chr11_-_107238956 2.55 ENSMUST00000134763.2
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr8_+_59365291 2.54 ENSMUST00000160055.2
BC030500
cDNA sequence BC030500
chr7_+_18962252 2.52 ENSMUST00000063976.9
Opa3
optic atrophy 3
chr8_+_94537910 2.46 ENSMUST00000138659.9
Gnao1
guanine nucleotide binding protein, alpha O
chr2_-_45001141 2.40 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr3_-_95811993 2.36 ENSMUST00000147962.3
ENSMUST00000036181.15
Car14
carbonic anhydrase 14
chr10_+_69761630 2.35 ENSMUST00000182029.8
Ank3
ankyrin 3, epithelial
chr16_-_4698148 2.29 ENSMUST00000037843.7
Ubald1
UBA-like domain containing 1
chr17_+_93506435 2.25 ENSMUST00000234646.2
ENSMUST00000234081.2
Adcyap1
adenylate cyclase activating polypeptide 1
chr18_-_43820759 2.17 ENSMUST00000082254.8
Jakmip2
janus kinase and microtubule interacting protein 2
chr11_-_98220466 2.15 ENSMUST00000041685.7
Neurod2
neurogenic differentiation 2
chr3_-_33136153 2.13 ENSMUST00000108225.10
Pex5l
peroxisomal biogenesis factor 5-like
chr17_+_93506590 2.07 ENSMUST00000064775.8
Adcyap1
adenylate cyclase activating polypeptide 1
chr2_+_154042291 2.01 ENSMUST00000028987.7
Bpifb1
BPI fold containing family B, member 1
chr8_+_66838927 1.97 ENSMUST00000039540.12
ENSMUST00000110253.3
Marchf1
membrane associated ring-CH-type finger 1
chr6_+_8948608 1.90 ENSMUST00000160300.2
Nxph1
neurexophilin 1
chr1_+_179788675 1.88 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
Cdc42bpa
CDC42 binding protein kinase alpha
chr8_-_65489791 1.85 ENSMUST00000124790.8
Apela
apelin receptor early endogenous ligand
chr7_+_119499322 1.82 ENSMUST00000106516.2
Lyrm1
LYR motif containing 1
chr5_+_102629365 1.75 ENSMUST00000112854.8
Arhgap24
Rho GTPase activating protein 24
chr4_+_102287244 1.72 ENSMUST00000172616.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_88762971 1.71 ENSMUST00000212694.2
Gon4l
gon-4-like (C.elegans)
chr1_-_97904958 1.65 ENSMUST00000161567.8
Pam
peptidylglycine alpha-amidating monooxygenase
chr9_+_53757448 1.65 ENSMUST00000048485.7
Sln
sarcolipin
chr7_-_119078472 1.65 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
Umod
uromodulin
chr3_-_123483772 1.64 ENSMUST00000172537.3
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr7_-_119078330 1.63 ENSMUST00000207460.2
Umod
uromodulin
chr18_+_69652880 1.61 ENSMUST00000200813.4
Tcf4
transcription factor 4
chr8_-_65489834 1.57 ENSMUST00000142822.4
Apela
apelin receptor early endogenous ligand
chr12_+_119291343 1.54 ENSMUST00000221917.2
Macc1
metastasis associated in colon cancer 1
chr1_-_158642039 1.52 ENSMUST00000161589.3
Pappa2
pappalysin 2
chr2_-_86906161 1.52 ENSMUST00000214049.2
Olfr1107
olfactory receptor 1107
chr10_+_38841511 1.49 ENSMUST00000019992.6
Lama4
laminin, alpha 4
chrX_+_100419965 1.43 ENSMUST00000119080.8
Gjb1
gap junction protein, beta 1
chr9_-_103569984 1.37 ENSMUST00000049452.15
Tmem108
transmembrane protein 108
chr4_-_135221926 1.35 ENSMUST00000102549.10
Nipal3
NIPA-like domain containing 3
chr1_-_170695328 1.31 ENSMUST00000027974.7
Atf6
activating transcription factor 6
chr9_-_101076198 1.29 ENSMUST00000066773.9
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_160701523 1.26 ENSMUST00000103112.8
Zhx3
zinc fingers and homeoboxes 3
chr4_-_135221810 1.24 ENSMUST00000105856.9
Nipal3
NIPA-like domain containing 3
chr3_+_133942244 1.23 ENSMUST00000181904.3
Cxxc4
CXXC finger 4
chr15_+_102012782 1.23 ENSMUST00000230474.2
Tns2
tensin 2
chrX_+_118836893 1.20 ENSMUST00000040961.3
ENSMUST00000113366.2
Pabpc5
poly(A) binding protein, cytoplasmic 5
chr2_-_45000389 1.18 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr14_+_48358267 1.11 ENSMUST00000073150.6
Peli2
pellino 2
chr6_-_58449863 1.06 ENSMUST00000226390.2
Vmn1r31
vomeronasal 1 receptor 31
chr6_+_132824105 1.06 ENSMUST00000071696.2
Tas2r123
taste receptor, type 2, member 123
chr1_+_70764874 1.05 ENSMUST00000053922.12
ENSMUST00000161937.2
ENSMUST00000162182.2
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chrX_-_42363663 1.01 ENSMUST00000016294.8
Tenm1
teneurin transmembrane protein 1
chr5_-_3707166 0.98 ENSMUST00000196304.2
Gatad1
GATA zinc finger domain containing 1
chr15_+_43340609 0.95 ENSMUST00000022962.8
Emc2
ER membrane protein complex subunit 2
chr9_+_47441471 0.88 ENSMUST00000114548.8
ENSMUST00000152459.8
ENSMUST00000143026.9
ENSMUST00000085909.9
ENSMUST00000114547.8
ENSMUST00000239368.2
ENSMUST00000214542.2
ENSMUST00000034581.4
Cadm1
cell adhesion molecule 1
chr16_-_33916354 0.88 ENSMUST00000114973.9
ENSMUST00000232157.2
ENSMUST00000114964.8
Kalrn
kalirin, RhoGEF kinase
chr1_+_179788037 0.83 ENSMUST00000097453.9
ENSMUST00000111117.8
Cdc42bpa
CDC42 binding protein kinase alpha
chr15_-_48655329 0.77 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
Csmd3
CUB and Sushi multiple domains 3
chr10_+_111342147 0.76 ENSMUST00000164773.2
Phlda1
pleckstrin homology like domain, family A, member 1
chr19_-_11852453 0.74 ENSMUST00000213954.2
ENSMUST00000217617.2
Olfr1419
olfactory receptor 1419
chr5_+_143803540 0.73 ENSMUST00000100487.6
Eif2ak1
eukaryotic translation initiation factor 2 alpha kinase 1
chr3_+_96152813 0.72 ENSMUST00000078756.7
ENSMUST00000090779.4
H2ac18
Gm20634
H2A clustered histone 18
predicted gene 20634
chr5_-_108943211 0.72 ENSMUST00000004943.2
Tmed11
transmembrane p24 trafficking protein 11
chr17_-_35265702 0.70 ENSMUST00000097338.11
Msh5
mutS homolog 5
chr14_+_33193765 0.70 ENSMUST00000208577.2
Frmpd2
FERM and PDZ domain containing 2
chr3_+_55689921 0.66 ENSMUST00000075422.6
Mab21l1
mab-21-like 1
chr17_+_35188888 0.62 ENSMUST00000173680.2
Gm20481
predicted gene 20481
chr6_-_139478919 0.54 ENSMUST00000170650.3
Rergl
RERG/RAS-like
chr12_-_40249314 0.53 ENSMUST00000095760.3
Lsmem1
leucine-rich single-pass membrane protein 1
chr2_-_86944911 0.50 ENSMUST00000216088.3
Olfr259
olfactory receptor 259
chr10_-_82328442 0.48 ENSMUST00000177934.3
Gm1553
predicted gene 1553
chr3_+_85946145 0.44 ENSMUST00000238331.2
Sh3d19
SH3 domain protein D19
chr3_-_129597679 0.41 ENSMUST00000185462.7
ENSMUST00000179187.2
Lrit3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr11_+_78356523 0.40 ENSMUST00000001126.4
Slc46a1
solute carrier family 46, member 1
chr19_+_45433899 0.40 ENSMUST00000224478.2
Btrc
beta-transducin repeat containing protein
chr19_-_9065309 0.39 ENSMUST00000025554.3
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
chr6_+_34840151 0.38 ENSMUST00000202010.2
Tmem140
transmembrane protein 140
chr3_-_96147592 0.36 ENSMUST00000074976.8
H2ac19
H2A clustered histone 19
chr6_+_14901343 0.36 ENSMUST00000115477.8
Foxp2
forkhead box P2
chr17_-_21110913 0.27 ENSMUST00000061278.2
Vmn1r231
vomeronasal 1 receptor 231
chr10_-_33662700 0.26 ENSMUST00000223295.2
Sult3a2
sulfotransferase family 3A, member 2
chr14_-_50479161 0.26 ENSMUST00000214388.2
Olfr731
olfactory receptor 731
chr7_+_18962301 0.26 ENSMUST00000161711.2
Opa3
optic atrophy 3
chr4_-_102883905 0.25 ENSMUST00000084382.6
ENSMUST00000106869.3
Insl5
insulin-like 5
chr2_+_181408833 0.24 ENSMUST00000108756.8
Myt1
myelin transcription factor 1
chr1_-_39844467 0.23 ENSMUST00000171319.4
Gm3646
predicted gene 3646
chr7_-_107856399 0.21 ENSMUST00000211508.3
Olfr488
olfactory receptor 488
chr6_+_34840057 0.20 ENSMUST00000074949.4
Tmem140
transmembrane protein 140
chr4_-_87724533 0.18 ENSMUST00000126353.8
ENSMUST00000149357.8
Mllt3
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr11_-_86884507 0.16 ENSMUST00000018571.5
Ypel2
yippee like 2
chr5_+_104318542 0.16 ENSMUST00000112771.2
Dspp
dentin sialophosphoprotein
chr3_-_113325938 0.14 ENSMUST00000132353.2
Amy2a1
amylase 2a1
chrX_+_132751729 0.14 ENSMUST00000033602.9
Tnmd
tenomodulin
chr7_+_103593644 0.12 ENSMUST00000216006.2
Olfr633
olfactory receptor 633
chr3_-_102871440 0.11 ENSMUST00000058899.13
Nr1h5
nuclear receptor subfamily 1, group H, member 5
chr18_-_47466378 0.07 ENSMUST00000126684.2
ENSMUST00000156422.8
Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_181409075 0.04 ENSMUST00000108757.9
Myt1
myelin transcription factor 1
chr5_+_43673093 0.04 ENSMUST00000144558.3
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr6_+_14901439 0.01 ENSMUST00000128567.8
Foxp2
forkhead box P2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.1 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
1.6 4.8 GO:0061193 taste bud development(GO:0061193)
1.4 4.1 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
1.3 6.5 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
1.1 4.3 GO:0007412 axon target recognition(GO:0007412)
1.1 13.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 2.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.9 4.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.8 3.3 GO:0072021 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.8 3.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.7 8.9 GO:0070842 aggresome assembly(GO:0070842)
0.6 6.6 GO:0033227 dsRNA transport(GO:0033227)
0.5 2.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 3.6 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 5.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.4 4.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 11.8 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.1 GO:0006449 regulation of translational termination(GO:0006449)
0.3 7.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 2.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 2.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 1.7 GO:0031179 peptide modification(GO:0031179)
0.2 1.6 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.2 2.9 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.2 1.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 3.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.4 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 2.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.9 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.4 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 1.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 2.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.2 GO:0014850 response to muscle activity(GO:0014850)
0.1 3.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.4 GO:0051958 heme transport(GO:0015886) methotrexate transport(GO:0051958)
0.1 2.7 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175) cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.0 2.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 3.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.5 13.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 3.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 3.6 GO:0043083 synaptic cleft(GO:0043083)
0.3 2.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 4.8 GO:0030061 mitochondrial crista(GO:0030061)
0.2 5.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 5.4 GO:0097440 apical dendrite(GO:0097440)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.5 GO:0005605 basal lamina(GO:0005605)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 11.8 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.4 GO:0005922 connexon complex(GO:0005922)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 10.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.8 GO:0043195 terminal bouton(GO:0043195)
0.0 3.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 3.3 GO:0000922 spindle pole(GO:0000922)
0.0 2.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.3 5.4 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
1.1 6.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.1 4.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 3.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.7 11.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 3.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 2.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 2.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 7.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 3.3 GO:0019864 IgG binding(GO:0019864)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.6 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 2.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 6.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 13.7 GO:0030507 spectrin binding(GO:0030507)
0.1 4.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 4.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 5.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.4 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 3.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 3.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.7 GO:0030552 cAMP binding(GO:0030552)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 7.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 8.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.8 PID SHP2 PATHWAY SHP2 signaling
0.1 3.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 11.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 4.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 4.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 7.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling