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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxc1

Z-value: 1.44

Motif logo

Transcription factors associated with Foxc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000050295.5 Foxc1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxc1mm39_v1_chr13_+_31990604_31990633-0.343.7e-03Click!

Activity profile of Foxc1 motif

Sorted Z-values of Foxc1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxc1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_103099262 14.61 ENSMUST00000170904.2
transferrin
chr11_+_108286114 13.22 ENSMUST00000000049.6
apolipoprotein H
chr19_+_40078132 13.20 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr9_+_123603605 11.58 ENSMUST00000180093.2
chemokine (C-C motif) receptor 9
chr8_+_105775224 11.26 ENSMUST00000093222.13
ENSMUST00000093223.5
carboxylesterase 3A
chr14_-_31362909 10.26 ENSMUST00000022437.16
2-hydroxyacyl-CoA lyase 1
chr6_+_41520150 10.20 ENSMUST00000103295.2
T cell receptor beta joining 2-3
chr1_-_172722589 10.14 ENSMUST00000027824.7
serum amyloid P-component
chr14_-_31362835 9.79 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr8_+_105810380 9.55 ENSMUST00000093221.13
ENSMUST00000074403.13
carboxylesterase 3B
chr11_+_69945157 8.23 ENSMUST00000108585.9
ENSMUST00000018699.13
asialoglycoprotein receptor 1
chr14_+_54043954 8.00 ENSMUST00000103672.9
ENSMUST00000186545.2
T cell receptor alpha variable 17
chr15_+_80507671 7.91 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr14_+_53913598 7.39 ENSMUST00000103662.6
T cell receptor alpha variable 9-4
chr7_+_30193047 7.36 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chr5_+_146016064 7.33 ENSMUST00000035571.10
cytochrome P450, family 3, subfamily a, polypeptide 59
chr9_-_44920899 6.97 ENSMUST00000102832.3
CD3 antigen, epsilon polypeptide
chr6_-_55152002 6.72 ENSMUST00000003569.6
indolethylamine N-methyltransferase
chr16_-_48592319 6.64 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr9_+_123596276 6.47 ENSMUST00000166236.9
ENSMUST00000111454.4
ENSMUST00000168910.2
chemokine (C-C motif) receptor 9
chr16_+_17149235 6.17 ENSMUST00000023450.15
ENSMUST00000231884.2
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr14_+_53129643 6.08 ENSMUST00000199746.5
ENSMUST00000178824.2
T cell receptor alpha variable 9D-2
chr16_-_48592372 6.06 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr6_+_41118120 5.89 ENSMUST00000103273.3
T cell receptor beta, variable 15
chr12_-_73093953 5.87 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr2_-_10135449 5.75 ENSMUST00000042290.14
inter-alpha trypsin inhibitor, heavy chain 2
chr7_+_119360141 5.34 ENSMUST00000106528.8
ENSMUST00000106527.8
ENSMUST00000063770.10
ENSMUST00000106529.8
acyl-CoA synthetase medium-chain family member 3
chr16_-_19703014 5.32 ENSMUST00000100083.5
ENSMUST00000231564.2
RIKEN cDNA A930003A15 gene
chr2_+_58644922 5.20 ENSMUST00000059102.13
uridine phosphorylase 2
chr2_+_58645189 5.19 ENSMUST00000102755.4
ENSMUST00000230627.2
ENSMUST00000229923.2
uridine phosphorylase 2
chr10_+_127157784 5.04 ENSMUST00000219511.2
Rho GTPase activating protein 9
chr11_+_70410009 4.82 ENSMUST00000057685.3
glycolipid transfer protein domain containing 2
chr12_-_113386312 4.80 ENSMUST00000177715.8
ENSMUST00000103426.3
immunoglobulin heavy constant mu
chr14_+_53980561 4.78 ENSMUST00000103667.6
T cell receptor alpha variable 16
chr8_-_25066313 4.72 ENSMUST00000121992.2
indoleamine 2,3-dioxygenase 2
chr3_+_94284739 4.63 ENSMUST00000197040.5
RAR-related orphan receptor gamma
chr9_+_110248815 4.59 ENSMUST00000035061.9
neutrophilic granule protein
chr2_-_103315483 4.41 ENSMUST00000028610.10
catalase
chr8_-_84769170 4.38 ENSMUST00000005601.9
interleukin 27 receptor, alpha
chr14_-_52252318 4.29 ENSMUST00000228051.2
zinc finger protein 219
chr3_+_94284812 4.22 ENSMUST00000200009.2
RAR-related orphan receptor gamma
chr14_+_54453748 4.18 ENSMUST00000103736.2
T cell receptor alpha joining 4
chr14_+_31363004 4.17 ENSMUST00000090147.7
biotinidase
chr10_+_127159609 4.10 ENSMUST00000069548.7
Rho GTPase activating protein 9
chr10_+_127159568 4.08 ENSMUST00000219026.2
Rho GTPase activating protein 9
chr10_-_89369432 4.02 ENSMUST00000105297.2
nuclear receptor subfamily 1, group H, member 4
chr14_+_53153256 3.98 ENSMUST00000197007.2
ENSMUST00000103593.3
T cell receptor alpha variable 12D-2
chr3_-_14873406 3.98 ENSMUST00000181860.8
ENSMUST00000144327.3
carbonic anhydrase 1
chr14_+_54439232 3.89 ENSMUST00000103724.2
T cell receptor alpha joining 17
chr3_+_40904253 3.84 ENSMUST00000048490.13
La ribonucleoprotein domain family, member 1B
chr8_+_118428643 3.83 ENSMUST00000034304.9
hydroxysteroid (17-beta) dehydrogenase 2
chr13_-_19495474 3.59 ENSMUST00000197113.2
T cell receptor gamma joining 2
chr14_+_54429757 3.48 ENSMUST00000103714.2
T cell receptor alpha joining 27
chr14_+_53245069 3.44 ENSMUST00000178650.3
T cell receptor alpha variable 6D-7
chr9_+_123635556 3.30 ENSMUST00000216072.2
chemokine (C-X-C motif) receptor 6
chr5_-_135601887 3.29 ENSMUST00000004936.10
ENSMUST00000201401.2
chemokine (C-C motif) ligand 24
chr5_-_24732200 3.23 ENSMUST00000088311.6
gastrulation brain homeobox 1
chr9_+_7558449 3.22 ENSMUST00000018765.4
matrix metallopeptidase 8
chr17_-_52117894 3.21 ENSMUST00000176669.8
special AT-rich sequence binding protein 1
chr11_+_100973391 3.20 ENSMUST00000001806.10
ENSMUST00000107308.4
Coenzyme A synthase
chr7_+_79048884 3.15 ENSMUST00000137667.3
Fanconi anemia, complementation group I
chr1_+_75213171 3.09 ENSMUST00000187058.7
DnaJ heat shock protein family (Hsp40) member B2
chr7_+_114344920 3.09 ENSMUST00000136645.8
ENSMUST00000169913.8
INSC spindle orientation adaptor protein
chr14_+_53743184 3.01 ENSMUST00000103583.5
T cell receptor alpha variable 10
chr14_-_52252432 3.01 ENSMUST00000226527.2
zinc finger protein 219
chr14_+_53167246 2.95 ENSMUST00000177703.3
T cell receptor alpha variable 12D-3
chr3_-_102871440 2.89 ENSMUST00000058899.13
nuclear receptor subfamily 1, group H, member 5
chr14_+_78141679 2.81 ENSMUST00000022591.16
ENSMUST00000169978.2
ENSMUST00000227903.2
epithelial stromal interaction 1 (breast)
chr17_+_34457868 2.80 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
histocompatibility 2, O region beta locus
chr11_+_61017573 2.79 ENSMUST00000010286.8
ENSMUST00000146033.8
ENSMUST00000139422.8
tumor necrosis factor receptor superfamily, member 13b
chr1_+_75213082 2.79 ENSMUST00000055223.14
ENSMUST00000082158.13
ENSMUST00000188346.7
DnaJ heat shock protein family (Hsp40) member B2
chr11_-_53509485 2.76 ENSMUST00000000889.7
interleukin 4
chr9_+_54771064 2.73 ENSMUST00000034843.9
iron responsive element binding protein 2
chr11_-_84058292 2.54 ENSMUST00000050771.8
predicted gene 11437
chr9_+_44245981 2.50 ENSMUST00000052686.4
H2A.X variant histone
chr14_-_50425655 2.48 ENSMUST00000205837.3
olfactory receptor 730
chr1_+_75213114 2.45 ENSMUST00000188290.7
DnaJ heat shock protein family (Hsp40) member B2
chr8_-_46605196 2.44 ENSMUST00000110378.9
sorting nexin 25
chrX_-_108056995 2.40 ENSMUST00000033597.9
high-mobility group nucleosome binding domain 5
chr14_+_53059379 2.39 ENSMUST00000197754.2
T cell receptor alpha variable 6D-6
chr4_+_100336003 2.35 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr14_+_53029773 2.34 ENSMUST00000178426.4
T cell receptor alpha variable 9D-1
chr1_+_75213044 2.23 ENSMUST00000188931.7
DnaJ heat shock protein family (Hsp40) member B2
chr13_+_19526322 2.22 ENSMUST00000184430.2
T cell receptor gamma joining 4
chr17_+_57318469 2.15 ENSMUST00000210548.2
predicted gene, 17949
chr14_+_53220913 2.15 ENSMUST00000167409.2
T cell receptor alpha variable 9D-4
chr1_+_135980508 2.06 ENSMUST00000112068.10
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr13_+_38010203 2.02 ENSMUST00000128570.9
ras responsive element binding protein 1
chr6_-_129637519 1.98 ENSMUST00000119533.2
ENSMUST00000145984.8
ENSMUST00000118401.8
ENSMUST00000112057.9
ENSMUST00000071920.11
killer cell lectin-like receptor subfamily C, member 2
chr17_+_48666919 1.96 ENSMUST00000224001.2
ENSMUST00000024792.8
ENSMUST00000225849.2
triggering receptor expressed on myeloid cells-like 1
chr1_+_135980488 1.95 ENSMUST00000160641.8
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr14_-_48900192 1.94 ENSMUST00000122009.8
orthodenticle homeobox 2
chr1_-_136888118 1.91 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr15_-_78290038 1.87 ENSMUST00000058659.9
thiosulfate sulfurtransferase, mitochondrial
chr5_-_33591320 1.86 ENSMUST00000173348.2
NK1 homeobox 1
chr8_-_120301883 1.83 ENSMUST00000212198.2
ENSMUST00000212065.2
ENSMUST00000036049.6
hydroxysteroid dehydrogenase like 1
chr10_-_78448514 1.81 ENSMUST00000205085.2
olfactory receptor 1357
chr1_+_75213258 1.81 ENSMUST00000185654.3
DnaJ heat shock protein family (Hsp40) member B2
chrY_+_1010543 1.81 ENSMUST00000091197.4
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr10_+_115405891 1.75 ENSMUST00000173620.2
RIKEN cDNA A930009A15 gene
chr11_-_78441584 1.74 ENSMUST00000103242.5
transmembrane protein 97
chr12_+_76417040 1.74 ENSMUST00000042779.4
zinc finger and BTB domain containing 1
chr14_+_53239170 1.73 ENSMUST00000179701.2
T cell receptor alpha variable 5D-4
chr4_-_116484675 1.72 ENSMUST00000081182.5
ENSMUST00000030457.12
nuclear autoantigenic sperm protein (histone-binding)
chr2_-_172212426 1.72 ENSMUST00000109139.8
ENSMUST00000028997.8
ENSMUST00000109140.10
aurora kinase A
chr18_-_3280999 1.63 ENSMUST00000049942.13
cAMP responsive element modulator
chr2_+_174485327 1.63 ENSMUST00000059452.6
zinc finger protein 831
chr17_+_35056219 1.60 ENSMUST00000173995.2
ENSMUST00000174092.8
decapping exoribonuclease
chr6_-_42442130 1.59 ENSMUST00000216650.2
olfactory receptor 458
chr5_-_66308666 1.58 ENSMUST00000201561.4
RNA binding motif protein 47
chr5_-_66308421 1.57 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr5_+_16758777 1.54 ENSMUST00000030683.8
hepatocyte growth factor
chr14_-_52733146 1.53 ENSMUST00000206931.2
ENSMUST00000206062.4
olfactory receptor 1507
chr13_-_40441487 1.52 ENSMUST00000054635.8
orofacial cleft 1 candidate 1
chr5_+_147125488 1.51 ENSMUST00000065382.6
GS homeobox 1
chr7_-_110682204 1.51 ENSMUST00000161051.8
ENSMUST00000160132.8
ENSMUST00000162415.9
eukaryotic translation initiation factor 4, gamma 2
chr1_+_88093726 1.51 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr18_-_3281089 1.50 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr13_-_49473695 1.46 ENSMUST00000110086.2
FYVE, RhoGEF and PH domain containing 3
chr15_+_10177709 1.45 ENSMUST00000124470.8
prolactin receptor
chr1_+_107439145 1.42 ENSMUST00000009356.11
ENSMUST00000064916.9
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr6_-_30680502 1.41 ENSMUST00000133373.8
centrosomal protein 41
chr6_-_68746087 1.41 ENSMUST00000103333.4
immunoglobulin kappa chain variable 4-91
chr9_-_51240201 1.40 ENSMUST00000039959.11
ENSMUST00000238450.3
RIKEN cDNA 1810046K07 gene
chr14_+_63235512 1.35 ENSMUST00000100492.5
defensin beta 47
chr10_+_127927443 1.33 ENSMUST00000238829.2
ENSMUST00000217851.2
ENSMUST00000220049.2
bromodomain adjacent to zinc finger domain, 2A
chr19_+_12839106 1.32 ENSMUST00000059675.4
olfactory receptor 1444
chr11_+_3152683 1.31 ENSMUST00000125637.8
eukaryotic translation initiation factor 4E nuclear import factor 1
chrX_-_94521712 1.30 ENSMUST00000033549.3
ankyrin repeat and SOCS box-containing 12
chr14_+_53370136 1.29 ENSMUST00000181793.3
T cell receptor alpha variable 6N-6
chr17_-_36582721 1.28 ENSMUST00000042717.13
tripartite motif-containing 39
chr10_+_128540049 1.27 ENSMUST00000217836.2
premelanosome protein
chr4_-_94817025 1.25 ENSMUST00000030309.6
equatorin, sperm acrosome associated
chr5_+_88635834 1.22 ENSMUST00000199104.5
ENSMUST00000031222.9
enamelin
chr13_-_18556626 1.21 ENSMUST00000139064.10
ENSMUST00000175703.9
POU domain, class 6, transcription factor 2
chr10_+_39245746 1.20 ENSMUST00000063091.13
ENSMUST00000099967.10
ENSMUST00000126486.8
Fyn proto-oncogene
chr9_-_106768601 1.19 ENSMUST00000069036.14
mesencephalic astrocyte-derived neurotrophic factor
chr11_+_3152874 1.18 ENSMUST00000179770.8
ENSMUST00000110048.8
eukaryotic translation initiation factor 4E nuclear import factor 1
chr18_-_78166595 1.16 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr19_-_46314945 1.15 ENSMUST00000225781.2
ENSMUST00000223903.2
pleckstrin and Sec7 domain containing
chr8_+_120301974 1.13 ENSMUST00000093100.3
dynein, axonemal assembly factor 1
chr14_+_53370308 1.12 ENSMUST00000103613.3
T cell receptor alpha variable 6N-6
chr11_-_4544751 1.12 ENSMUST00000109943.10
myotubularin related protein 3
chr3_+_94744844 1.09 ENSMUST00000107270.9
pogo transposable element with ZNF domain
chr6_-_42453259 1.07 ENSMUST00000204324.3
ENSMUST00000203396.3
olfactory receptor 457
chr3_-_37180093 1.06 ENSMUST00000029275.6
interleukin 2
chr8_-_69541852 1.06 ENSMUST00000037478.13
ENSMUST00000148856.2
solute carrier family 18 (vesicular monoamine), member 1
chr15_-_100497863 1.04 ENSMUST00000073837.13
POU domain, class 6, transcription factor 1
chr12_-_69245191 1.03 ENSMUST00000021356.6
dynein, axonemal assembly factor 2
chr6_+_42382368 1.03 ENSMUST00000070178.5
taste receptor, type 2, member 135
chr3_-_89905547 1.02 ENSMUST00000199740.2
ENSMUST00000198782.2
HCLS1 associated X-1
chr9_-_56759229 1.00 ENSMUST00000055036.7
outer dense fiber of sperm tails 3-like 1
chr18_+_65021974 1.00 ENSMUST00000225261.3
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr1_-_16689660 1.00 ENSMUST00000117146.9
ubiquitin-conjugating enzyme E2W (putative)
chr10_-_23968192 0.99 ENSMUST00000092654.4
trace amine-associated receptor 8B
chr7_-_5128936 0.99 ENSMUST00000147835.4
RAS-like, family 2, locus 9
chrX_+_100492684 0.98 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr16_+_35803794 0.97 ENSMUST00000173555.8
karyopherin (importin) alpha 1
chr15_+_78481247 0.96 ENSMUST00000043069.6
ENSMUST00000231180.2
ENSMUST00000229796.2
ENSMUST00000229295.2
cytohesin 4
chr4_+_49521176 0.96 ENSMUST00000042964.13
ENSMUST00000107696.2
zinc finger protein 189
chr5_-_100186728 0.94 ENSMUST00000153442.8
heterogeneous nuclear ribonucleoprotein D-like
chr18_+_58689296 0.93 ENSMUST00000025500.7
solute carrier family 27 (fatty acid transporter), member 6
chr3_+_68598757 0.93 ENSMUST00000107816.4
interleukin 12a
chr11_-_54158102 0.93 ENSMUST00000019058.6
interleukin 3
chr1_-_131025562 0.92 ENSMUST00000016672.11
MAP kinase-activated protein kinase 2
chr7_+_79674562 0.92 ENSMUST00000164056.9
ENSMUST00000166250.8
zinc finger protein 710
chr1_+_131890679 0.92 ENSMUST00000191034.2
ENSMUST00000177943.8
predicted gene 29103
solute carrier family 45, member 3
chr1_+_170060318 0.92 ENSMUST00000162752.2
SH2 domain containing 1B2
chr16_+_43067641 0.91 ENSMUST00000079441.13
ENSMUST00000114691.8
zinc finger and BTB domain containing 20
chr19_-_53932867 0.89 ENSMUST00000235688.2
ENSMUST00000235348.2
BBSome interacting protein 1
chr17_-_33904386 0.87 ENSMUST00000087582.13
heterogeneous nuclear ribonucleoprotein M
chr2_+_172392678 0.87 ENSMUST00000099058.10
transcription factor AP-2, gamma
chr5_-_30401416 0.82 ENSMUST00000125367.4
adhesion G protein-coupled receptor F3
chr18_-_37771772 0.82 ENSMUST00000058635.5
solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2
chr5_-_149559667 0.82 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr1_-_4430481 0.82 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chr6_-_93889483 0.81 ENSMUST00000205116.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr18_-_78166539 0.79 ENSMUST00000160292.8
solute carrier family 14 (urea transporter), member 1
chr5_+_16758897 0.79 ENSMUST00000196645.2
hepatocyte growth factor
chr11_+_104983022 0.78 ENSMUST00000021029.6
EF-hand calcium binding domain 3
chr17_-_37574640 0.77 ENSMUST00000080759.5
olfactory receptor 98
chr7_+_141996067 0.76 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr8_+_46604786 0.76 ENSMUST00000154040.2
cilia and flagella associated protein 97
chr12_-_85421467 0.76 ENSMUST00000040766.9
transmembrane p24 trafficking protein 10
chr1_-_132953068 0.76 ENSMUST00000186617.7
ENSMUST00000067429.10
ENSMUST00000067398.13
ENSMUST00000188090.7
transformed mouse 3T3 cell double minute 4
chr18_-_6490808 0.75 ENSMUST00000028100.13
ENSMUST00000050542.6
enhancer of polycomb homolog 1
chr5_+_45611093 0.72 ENSMUST00000053250.5
clarin 2
chr9_+_27308087 0.71 ENSMUST00000214158.2
ENSMUST00000034473.7
spermatogenesis associated 19
chr13_+_78173013 0.71 ENSMUST00000175955.4
POU domain class 5, transcription factor 2
chr12_-_115031622 0.69 ENSMUST00000194257.2
immunoglobulin heavy variable V8-5
chr19_-_11301919 0.69 ENSMUST00000159269.2
membrane-spanning 4-domains, subfamily A, member 7
chr1_+_163822438 0.68 ENSMUST00000045694.14
ENSMUST00000111490.2
methyltransferase like 18
chrX_-_56384089 0.66 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_-_74918745 0.64 ENSMUST00000223033.2
ENSMUST00000222588.2
calpastatin
chrX_-_74460137 0.64 ENSMUST00000033542.11
mature T cell proliferation 1
chr17_-_33904345 0.62 ENSMUST00000234474.2
ENSMUST00000139302.8
ENSMUST00000114385.9
heterogeneous nuclear ribonucleoprotein M
chr3_+_89986925 0.61 ENSMUST00000118566.8
ENSMUST00000119158.8
tropomyosin 3, gamma
chr16_-_88571089 0.60 ENSMUST00000054223.4
RIKEN cDNA 2310057N15 gene
chrX_-_74460168 0.59 ENSMUST00000033543.14
ENSMUST00000149863.3
ENSMUST00000114081.2
C-x(9)-C motif containing 4
mature T cell proliferation 1
chr4_-_117786690 0.59 ENSMUST00000097913.9
artemin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.0 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
3.4 10.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.9 20.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
2.5 7.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.1 12.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
2.1 14.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
2.0 5.9 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
1.8 12.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.7 13.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.6 4.8 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.2 6.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
1.2 12.9 GO:0072615 interleukin-17 secretion(GO:0072615)
1.1 4.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.1 13.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.1 3.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.9 2.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 2.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.7 7.0 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.6 1.9 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.6 1.7 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.4 4.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.7 GO:0002572 pro-T cell differentiation(GO:0002572)
0.4 4.7 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.4 3.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 1.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.4 1.2 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.3 1.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 4.4 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.3 4.4 GO:0009650 UV protection(GO:0009650)
0.3 2.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 1.9 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 0.8 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.3 3.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.1 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 1.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.9 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.2 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 0.9 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.2 1.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 2.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.6 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.2 0.6 GO:0009629 response to gravity(GO:0009629)
0.2 0.8 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 3.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 3.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 1.0 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.2 1.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 1.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 1.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 1.5 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.1 1.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 5.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.3 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 2.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 3.2 GO:0030574 collagen catabolic process(GO:0030574)
0.1 2.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 3.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.1 4.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 1.6 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 21.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.9 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 4.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 3.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 6.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.2 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.9 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.0 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.1 1.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.1 5.3 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 3.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 6.7 GO:0009308 amine metabolic process(GO:0009308)
0.0 9.4 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 2.4 GO:0016574 histone ubiquitination(GO:0016574)
0.0 1.0 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 1.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 7.1 GO:0007596 blood coagulation(GO:0007596)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 1.7 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.9 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 1.2 GO:0043467 regulation of generation of precursor metabolites and energy(GO:0043467)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 6.9 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.8 GO:0006413 translational initiation(GO:0006413)
0.0 3.8 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.3 GO:0014823 response to activity(GO:0014823)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 14.6 GO:0097433 dense body(GO:0097433)
0.9 10.4 GO:0045098 type III intermediate filament(GO:0045098)
0.7 4.8 GO:0019815 B cell receptor complex(GO:0019815)
0.6 19.7 GO:0042101 T cell receptor complex(GO:0042101)
0.6 13.2 GO:0042627 chylomicron(GO:0042627)
0.3 2.4 GO:0033503 HULC complex(GO:0033503)
0.3 1.7 GO:0042585 chromosome passenger complex(GO:0032133) germinal vesicle(GO:0042585)
0.3 1.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 3.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.5 GO:0042382 paraspeckles(GO:0042382)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 12.4 GO:0000502 proteasome complex(GO:0000502)
0.1 24.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.5 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.9 GO:0034464 BBSome(GO:0034464)
0.1 0.8 GO:0097542 ciliary tip(GO:0097542)
0.1 4.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 5.2 GO:0072562 blood microparticle(GO:0072562)
0.0 2.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 6.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
2.2 13.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.1 14.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
1.7 10.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.7 20.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.6 4.7 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
1.5 8.8 GO:0008142 oxysterol binding(GO:0008142)
1.5 7.3 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
1.3 10.1 GO:0001849 complement component C1q binding(GO:0001849)
1.1 4.4 GO:0004096 catalase activity(GO:0004096)
1.1 3.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.1 3.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.9 18.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.9 2.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.8 6.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.8 4.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.7 5.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.6 2.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.5 3.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5 12.4 GO:0070628 proteasome binding(GO:0070628)
0.5 3.3 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.4 1.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4 4.0 GO:0004064 arylesterase activity(GO:0004064)
0.3 1.9 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.3 0.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.3 0.9 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.3 2.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 1.9 GO:0015265 urea channel activity(GO:0015265)
0.3 1.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 1.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.9 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 7.4 GO:0071949 FAD binding(GO:0071949)
0.2 0.6 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 1.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 13.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 5.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 4.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 3.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.5 GO:1990405 protein antigen binding(GO:1990405)
0.1 2.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 20.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 2.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.3 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 13.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 6.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 4.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 5.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 4.0 GO:0038024 cargo receptor activity(GO:0038024)
0.0 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.0 4.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 11.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 4.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 8.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 4.5 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 11.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 13.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID AURORA A PATHWAY Aurora A signaling
0.0 3.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 20.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.5 10.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 12.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.4 21.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 4.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 10.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 7.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 4.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 11.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 4.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes