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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxd1

Z-value: 1.63

Motif logo

Transcription factors associated with Foxd1

Gene Symbol Gene ID Gene Info
ENSMUSG00000078302.6 Foxd1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd1mm39_v1_chr13_+_98490742_98490758-0.123.0e-01Click!

Activity profile of Foxd1 motif

Sorted Z-values of Foxd1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_+_162923474 23.09 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr6_+_135339543 17.09 ENSMUST00000205156.3
epithelial membrane protein 1
chr10_+_115653152 14.85 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr6_+_135339929 13.25 ENSMUST00000032330.16
epithelial membrane protein 1
chr17_+_47816042 13.15 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr15_+_80507671 13.01 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr5_-_138169509 12.47 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr17_+_47815968 12.43 ENSMUST00000182129.8
ENSMUST00000171031.8
cyclin D3
chr17_+_47816074 12.26 ENSMUST00000183177.8
ENSMUST00000182848.8
cyclin D3
chr10_+_96452860 12.15 ENSMUST00000038377.9
BTG anti-proliferation factor 1
chr3_-_27208010 11.19 ENSMUST00000108300.8
ENSMUST00000108298.9
ect2 oncogene
chr3_-_27207993 11.12 ENSMUST00000176242.9
ENSMUST00000176780.8
ect2 oncogene
chr17_+_35413415 10.51 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr11_+_3280401 10.01 ENSMUST00000045153.11
phosphoinositide-3-kinase interacting protein 1
chr5_-_138169253 9.98 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr17_+_47816137 9.76 ENSMUST00000182935.8
ENSMUST00000182506.8
cyclin D3
chrX_+_35152460 9.61 ENSMUST00000033419.13
dedicator of cytokinesis 11
chr5_+_31409021 8.86 ENSMUST00000054829.13
ENSMUST00000201625.4
ENSMUST00000201937.4
keratinocyte associated protein 3
chr11_+_33996920 8.70 ENSMUST00000052413.12
lymphocyte cytosolic protein 2
chr11_+_3280771 8.44 ENSMUST00000136536.8
ENSMUST00000093399.11
phosphoinositide-3-kinase interacting protein 1
chr11_+_3282424 8.39 ENSMUST00000136474.2
phosphoinositide-3-kinase interacting protein 1
chr6_+_29853745 7.69 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr6_-_83513222 7.67 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr17_+_47815998 7.54 ENSMUST00000183210.2
cyclin D3
chr10_+_96453408 7.44 ENSMUST00000218953.2
BTG anti-proliferation factor 1
chr1_-_45542442 7.40 ENSMUST00000086430.5
collagen, type V, alpha 2
chr3_+_96465265 7.40 ENSMUST00000074519.13
ENSMUST00000049093.8
thioredoxin interacting protein
chr11_+_33997114 7.31 ENSMUST00000109329.9
lymphocyte cytosolic protein 2
chr1_-_54965470 7.25 ENSMUST00000179030.8
ENSMUST00000044359.16
ankyrin repeat domain 44
chr1_+_12788720 7.20 ENSMUST00000088585.10
sulfatase 1
chr11_+_96820220 6.96 ENSMUST00000062172.6
proline rich 15-like
chr6_-_83513184 6.91 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr15_+_35296237 6.77 ENSMUST00000022952.6
odd-skipped related 2
chr19_-_41836514 6.77 ENSMUST00000059231.4
frequently rearranged in advanced T cell lymphomas 2
chr3_-_27207931 6.58 ENSMUST00000175857.2
ENSMUST00000177055.8
ENSMUST00000176535.8
ect2 oncogene
chr4_+_11191726 6.55 ENSMUST00000029866.16
ENSMUST00000108324.4
cyclin E2
chr5_-_148988110 6.55 ENSMUST00000110505.8
high mobility group box 1
chr7_+_110371811 6.53 ENSMUST00000005829.13
adenosine monophosphate deaminase 3
chr8_+_35274440 6.44 ENSMUST00000033930.5
dual specificity phosphatase 4
chr3_-_52012462 6.41 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr15_-_97729341 6.20 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr11_+_96820091 6.14 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr17_-_71158703 6.13 ENSMUST00000166395.9
TGFB-induced factor homeobox 1
chr5_+_21577640 5.90 ENSMUST00000035799.6
fibrinogen-like protein 2
chr12_-_15866763 5.87 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chr11_-_102255999 5.87 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr5_-_138169476 5.73 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr17_+_29712008 5.71 ENSMUST00000234665.2
proviral integration site 1
chr4_+_11191354 5.71 ENSMUST00000170901.8
cyclin E2
chr7_-_83304698 5.67 ENSMUST00000145610.8
interleukin 16
chr18_-_47466378 5.56 ENSMUST00000126684.2
ENSMUST00000156422.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_-_29204812 5.56 ENSMUST00000183096.8
ENSMUST00000085809.11
signal-induced proliferation-associated 1 like 3
chr8_+_106785434 5.51 ENSMUST00000212742.2
ENSMUST00000211991.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr2_-_59955995 5.50 ENSMUST00000112550.8
bromodomain adjacent to zinc finger domain, 2B
chr2_+_112096154 5.48 ENSMUST00000110991.9
solute carrier family 12, member 6
chr4_-_149760488 5.42 ENSMUST00000118704.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr9_+_96078340 5.26 ENSMUST00000034982.16
ENSMUST00000188008.7
ENSMUST00000188750.7
ENSMUST00000185644.7
transcription factor Dp 2
chr13_+_55593116 5.12 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
G protein-coupled receptor kinase 6
chr6_-_148847854 5.12 ENSMUST00000139355.8
ENSMUST00000146457.2
ENSMUST00000054080.15
SIN3-HDAC complex associated factor
chr4_+_132857816 5.10 ENSMUST00000084241.12
ENSMUST00000138831.2
WASP family, member 2
chr2_+_127967951 5.08 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
BCL2-like 11 (apoptosis facilitator)
chr11_-_54846873 5.08 ENSMUST00000155316.2
ENSMUST00000108889.10
ENSMUST00000126703.8
TNFAIP3 interacting protein 1
chr1_+_130793406 5.01 ENSMUST00000038829.7
Fc fragment of IgM receptor
chr14_-_68893253 4.82 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr3_-_129834788 4.78 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr17_+_23879448 4.75 ENSMUST00000062967.10
BICD family like cargo adaptor 2
chr12_+_71063431 4.73 ENSMUST00000125125.2
AT rich interactive domain 4A (RBP1-like)
chr15_+_61857226 4.64 ENSMUST00000161976.8
ENSMUST00000022971.8
myelocytomatosis oncogene
chr5_-_136595205 4.61 ENSMUST00000176778.8
cut-like homeobox 1
chr11_-_101117237 4.54 ENSMUST00000100417.3
ENSMUST00000107285.8
ENSMUST00000107284.8
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr8_-_85705338 4.49 ENSMUST00000064922.7
jun B proto-oncogene
chr19_+_56414114 4.48 ENSMUST00000238892.2
caspase 7
chr16_+_24266829 4.48 ENSMUST00000078988.10
LIM domain containing preferred translocation partner in lipoma
chr19_+_58748132 4.36 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr1_-_69726384 4.34 ENSMUST00000187184.7
IKAROS family zinc finger 2
chr6_+_54658609 4.28 ENSMUST00000190641.7
ENSMUST00000187701.2
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr15_-_98816012 4.27 ENSMUST00000023736.10
limb region 1 like
chr6_+_30541581 4.26 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr5_-_148988413 4.22 ENSMUST00000093196.11
high mobility group box 1
chr12_+_112645237 4.10 ENSMUST00000174780.2
ENSMUST00000169593.2
ENSMUST00000173942.2
zinc finger and BTB domain containing 42
chr18_-_80751327 4.09 ENSMUST00000236310.2
ENSMUST00000167977.8
ENSMUST00000035800.8
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr1_+_173501215 4.02 ENSMUST00000085876.12
interferon activated gene 208
chr10_-_4338032 4.02 ENSMUST00000100078.10
zinc finger and BTB domain containing 2
chr4_-_138452517 4.02 ENSMUST00000105811.9
UBX domain protein 10
chr15_+_61857390 4.02 ENSMUST00000159327.2
ENSMUST00000167731.8
myelocytomatosis oncogene
chr12_-_32000534 3.98 ENSMUST00000172314.9
high mobility group box transcription factor 1
chr19_-_7319157 3.98 ENSMUST00000164205.8
ENSMUST00000165286.8
ENSMUST00000168324.2
ENSMUST00000032557.15
MAP/microtubule affinity regulating kinase 2
chr19_-_27988393 3.96 ENSMUST00000172907.8
ENSMUST00000046898.17
regulatory factor X, 3 (influences HLA class II expression)
chr11_-_74480870 3.91 ENSMUST00000145524.2
ENSMUST00000102521.9
RAP1 GTPase activating protein 2
chr3_+_138566249 3.88 ENSMUST00000121826.3
tetraspanin 5
chr3_-_92922976 3.84 ENSMUST00000107301.2
ENSMUST00000029521.5
cysteine-rich C-terminal 1
chr2_-_163486998 3.76 ENSMUST00000017851.4
serine incorporator 3
chr3_-_143910926 3.76 ENSMUST00000120539.8
ENSMUST00000196264.5
LIM domain only 4
chr19_+_7534838 3.75 ENSMUST00000141887.8
ENSMUST00000136756.2
phospholipase A and acyltransferase 3
chr2_+_18069375 3.75 ENSMUST00000114671.8
ENSMUST00000114680.9
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr15_+_79232137 3.72 ENSMUST00000163691.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr19_+_45433899 3.71 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr2_+_112114906 3.68 ENSMUST00000053666.8
solute carrier family 12, member 6
chr6_+_142244145 3.67 ENSMUST00000041993.3
islet amyloid polypeptide
chr6_+_34840057 3.66 ENSMUST00000074949.4
transmembrane protein 140
chr1_-_64995982 3.65 ENSMUST00000097713.2
pleckstrin homology domain containing, family M, member 3
chr13_+_55357585 3.63 ENSMUST00000224973.2
ENSMUST00000099490.3
nuclear receptor-binding SET-domain protein 1
chr3_-_51248032 3.61 ENSMUST00000062009.14
ENSMUST00000194641.6
E74-like factor 2
chr3_-_133250889 3.60 ENSMUST00000197118.5
tet methylcytosine dioxygenase 2
chr19_-_7318798 3.57 ENSMUST00000165965.8
ENSMUST00000051711.16
ENSMUST00000169541.8
ENSMUST00000165989.2
MAP/microtubule affinity regulating kinase 2
chr16_-_4376471 3.56 ENSMUST00000230875.2
transcription factor AP4
chr9_+_96078299 3.52 ENSMUST00000165120.9
transcription factor Dp 2
chr6_-_148847633 3.46 ENSMUST00000132696.8
SIN3-HDAC complex associated factor
chr19_+_53317844 3.41 ENSMUST00000111737.3
ENSMUST00000025998.15
ENSMUST00000237837.2
MAX interactor 1, dimerization protein
chr10_+_101994841 3.39 ENSMUST00000020039.13
MGAT4 family, member C
chr19_+_41818409 3.39 ENSMUST00000087155.5
frequently rearranged in advanced T cell lymphomas
chr18_+_69652837 3.36 ENSMUST00000201410.4
ENSMUST00000202937.4
transcription factor 4
chr3_-_143908111 3.36 ENSMUST00000121796.8
LIM domain only 4
chr15_-_51855073 3.36 ENSMUST00000022927.11
RAD21 cohesin complex component
chr15_+_79231720 3.35 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr1_+_36550948 3.33 ENSMUST00000001166.14
ENSMUST00000097776.4
cyclin M3
chr7_-_25488060 3.31 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr11_+_120123727 3.30 ENSMUST00000122148.8
ENSMUST00000044985.14
BAH domain and coiled-coil containing 1
chr8_+_70826191 3.28 ENSMUST00000003659.9
cartilage oligomeric matrix protein
chr10_-_26249952 3.28 ENSMUST00000105519.10
ENSMUST00000040219.13
L3MBTL3 histone methyl-lysine binding protein
chr19_+_34268071 3.25 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr3_-_143908060 3.24 ENSMUST00000121112.6
LIM domain only 4
chr10_+_59942274 3.14 ENSMUST00000165024.3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr12_-_100691316 3.12 ENSMUST00000222731.2
ribosomal protein S6 kinase, polypeptide 5
chr3_+_102965910 3.12 ENSMUST00000199367.5
ENSMUST00000199049.5
ENSMUST00000197678.5
neuroblastoma ras oncogene
chr19_+_36325683 3.11 ENSMUST00000225920.2
polycomb group ring finger 5
chr9_+_13298301 3.08 ENSMUST00000159294.9
mastermind like transcriptional coactivator 2
chr19_+_7534816 3.08 ENSMUST00000136465.8
ENSMUST00000025925.11
phospholipase A and acyltransferase 3
chr6_-_124888643 3.06 ENSMUST00000032217.2
lymphocyte-activation gene 3
chr4_+_101365144 3.04 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr13_-_98951890 3.04 ENSMUST00000040340.16
ENSMUST00000179563.8
ENSMUST00000109403.2
FCH domain only 2
chr7_+_112806672 3.03 ENSMUST00000047321.9
ENSMUST00000210074.2
ENSMUST00000210238.2
aryl hydrocarbon receptor nuclear translocator-like
chr9_+_78522783 3.01 ENSMUST00000093812.5
CD109 antigen
chr9_+_45281483 2.99 ENSMUST00000085939.8
ENSMUST00000217381.2
FXYD domain-containing ion transport regulator 6
chr15_-_58187556 2.93 ENSMUST00000022985.2
kelch-like 38
chr19_+_5927821 2.88 ENSMUST00000145200.8
ENSMUST00000025732.14
ENSMUST00000125114.8
ENSMUST00000155697.8
solute carrier family 25, member 45
chr3_-_30067285 2.83 ENSMUST00000172694.8
MDS1 and EVI1 complex locus
chr7_+_90075762 2.82 ENSMUST00000061391.9
coiled-coil domain containing 89
chr10_+_101994719 2.81 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
MGAT4 family, member C
chr5_-_142803405 2.80 ENSMUST00000151477.8
trinucleotide repeat containing 18
chr9_+_56982622 2.80 ENSMUST00000167715.8
transcriptional regulator, SIN3A (yeast)
chr1_+_40720731 2.75 ENSMUST00000192345.2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr7_+_126359869 2.71 ENSMUST00000206272.2
mitogen-activated protein kinase 3
chr5_-_73789764 2.65 ENSMUST00000087177.4
leucine rich repeat containing 66
chr6_-_13677928 2.63 ENSMUST00000203078.2
ENSMUST00000045235.8
base methyltransferase of 25S rRNA 2
chr14_-_54651442 2.61 ENSMUST00000227334.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr8_+_66070661 2.59 ENSMUST00000110258.8
ENSMUST00000110256.8
ENSMUST00000110255.8
membrane associated ring-CH-type finger 1
chr3_-_30067537 2.59 ENSMUST00000108270.10
MDS1 and EVI1 complex locus
chr6_+_15185202 2.53 ENSMUST00000154448.2
forkhead box P2
chr5_-_137530214 2.50 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr7_+_24607042 2.46 ENSMUST00000151121.2
Rho guanine nucleotide exchange factor (GEF) 1
chr19_+_5927876 2.44 ENSMUST00000235340.2
solute carrier family 25, member 45
chr14_-_110992533 2.44 ENSMUST00000078386.4
SLIT and NTRK-like family, member 6
chr11_+_107438751 2.43 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
helicase with zinc finger domain
chr5_-_123127346 2.41 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr7_-_141614758 2.40 ENSMUST00000211000.2
ENSMUST00000209725.2
ENSMUST00000084418.4
MOB kinase activator 2
chr10_+_21758083 2.37 ENSMUST00000120509.8
serum/glucocorticoid regulated kinase 1
chr4_+_32238950 2.33 ENSMUST00000037416.13
BTB and CNC homology, basic leucine zipper transcription factor 2
chr12_-_86125793 2.32 ENSMUST00000003687.8
transforming growth factor, beta 3
chr19_-_29721012 2.30 ENSMUST00000175764.9
RIKEN cDNA 9930021J03 gene
chr2_+_181479647 2.23 ENSMUST00000029116.14
ENSMUST00000108754.8
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr3_-_37286714 2.21 ENSMUST00000161015.2
ENSMUST00000029273.8
interleukin 21
chr4_-_108690741 2.20 ENSMUST00000102740.8
ENSMUST00000102741.8
basic transcription factor 3-like 4
chr4_-_128699838 2.17 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr1_-_154692678 2.13 ENSMUST00000238369.2
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr8_-_35962641 2.13 ENSMUST00000033927.8
exoribonuclease 1
chr17_-_66191912 2.12 ENSMUST00000024905.11
ralA binding protein 1
chr9_+_7272514 2.11 ENSMUST00000015394.10
matrix metallopeptidase 13
chr1_+_179373935 2.09 ENSMUST00000040706.9
consortin, connexin sorting protein
chr7_+_126359763 2.05 ENSMUST00000091328.4
mitogen-activated protein kinase 3
chr5_+_25451771 2.05 ENSMUST00000144971.2
polypeptide N-acetylgalactosaminyltransferase 11
chr19_-_7319211 2.04 ENSMUST00000171393.8
MAP/microtubule affinity regulating kinase 2
chr4_+_94627513 2.02 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chr5_+_86952072 2.02 ENSMUST00000119339.8
ENSMUST00000120498.8
YTH domain containing 1
chr7_-_141614590 2.01 ENSMUST00000211206.2
MOB kinase activator 2
chr11_+_101623776 2.00 ENSMUST00000039152.14
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr10_-_93146825 1.97 ENSMUST00000151153.2
ELK3, member of ETS oncogene family
chr15_+_25752963 1.96 ENSMUST00000022882.12
ENSMUST00000135173.8
myosin X
chr3_+_32490525 1.95 ENSMUST00000108242.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr4_+_65042411 1.95 ENSMUST00000084501.4
pregnancy-associated plasma protein A
chr12_-_100691251 1.95 ENSMUST00000043599.7
ribosomal protein S6 kinase, polypeptide 5
chr11_-_102446947 1.91 ENSMUST00000143842.2
G patch domain containing 8
chr3_+_52175757 1.90 ENSMUST00000053764.7
forkhead box O1
chr2_-_84652890 1.85 ENSMUST00000028471.6
smoothelin-like 1
chr12_+_84463970 1.85 ENSMUST00000183146.2
ring finger protein 113A2
chr13_+_42454922 1.84 ENSMUST00000021796.9
endothelin 1
chr16_-_78887971 1.83 ENSMUST00000023566.11
ENSMUST00000060402.6
transmembrane protease, serine 15
chr4_-_59549243 1.83 ENSMUST00000173699.8
ENSMUST00000173884.8
ENSMUST00000102883.11
ENSMUST00000174586.8
polypyrimidine tract binding protein 3
chr7_-_143239600 1.83 ENSMUST00000208017.2
ENSMUST00000152703.2
tumor necrosis factor receptor superfamily, member 23
chr14_-_71004019 1.83 ENSMUST00000167242.8
exportin 7
chr5_-_147244074 1.83 ENSMUST00000031650.4
caudal type homeobox 2
chr4_+_101365052 1.82 ENSMUST00000038207.12
DnaJ heat shock protein family (Hsp40) member C6
chr5_+_3978266 1.81 ENSMUST00000044492.10
A kinase (PRKA) anchor protein (yotiao) 9
chr4_+_138452593 1.79 ENSMUST00000124660.7
ENSMUST00000030530.6
phospholipase A2, group IIC
chr16_+_25105560 1.78 ENSMUST00000056087.4
transformation related protein 63 regulated
chr18_+_69652550 1.78 ENSMUST00000201205.4
transcription factor 4
chr3_-_146475974 1.77 ENSMUST00000106137.8
protein kinase, cAMP dependent, catalytic, beta
chr17_-_48189815 1.76 ENSMUST00000154108.2
forkhead box P4
chr4_-_129534403 1.75 ENSMUST00000084264.12
taxilin alpha
chr11_+_96024612 1.71 ENSMUST00000167258.8
tubulin tyrosine ligase-like family, member 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.1 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
3.6 10.8 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
2.7 24.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
2.4 26.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
2.3 28.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.3 9.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.2 8.7 GO:0046722 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
2.1 55.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
2.0 5.9 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
1.9 7.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.7 5.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
1.4 28.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.4 4.1 GO:0060854 patterning of lymph vessels(GO:0060854)
1.4 6.8 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
1.2 7.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.2 4.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.2 4.8 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
1.2 10.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.1 3.3 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
1.1 3.2 GO:0031104 dendrite regeneration(GO:0031104)
1.1 3.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.0 4.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
1.0 5.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.0 30.3 GO:0032060 bleb assembly(GO:0032060)
0.9 3.6 GO:0019858 cytosine metabolic process(GO:0019858)
0.9 4.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.9 7.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 4.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.8 2.4 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.8 2.3 GO:0003032 detection of oxygen(GO:0003032)
0.8 3.8 GO:0009597 detection of virus(GO:0009597)
0.7 9.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.7 2.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.7 2.8 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.7 5.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.7 3.3 GO:0097350 dendritic cell apoptotic process(GO:0097048) neutrophil clearance(GO:0097350) regulation of dendritic cell apoptotic process(GO:2000668)
0.7 6.5 GO:0032264 IMP salvage(GO:0032264)
0.6 9.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.6 1.8 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.6 3.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.6 4.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 5.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.5 1.6 GO:0021759 globus pallidus development(GO:0021759)
0.5 6.9 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.5 1.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.5 2.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.5 2.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 10.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.5 4.7 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.5 7.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.5 3.7 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 1.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 2.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 1.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 2.4 GO:0060005 vestibular reflex(GO:0060005)
0.4 3.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.4 1.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 1.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 2.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.4 6.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.4 1.5 GO:0015886 heme transport(GO:0015886)
0.4 1.4 GO:0035574 histone H4-K20 demethylation(GO:0035574) regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 12.3 GO:0006270 DNA replication initiation(GO:0006270)
0.3 5.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 7.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3 4.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.3 2.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 4.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 4.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.3 5.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 1.0 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.3 2.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 5.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 3.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 3.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 6.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 0.9 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.3 4.4 GO:0006968 cellular defense response(GO:0006968)
0.3 7.8 GO:0042118 endothelial cell activation(GO:0042118)
0.3 4.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.3 1.4 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 1.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.3 1.9 GO:0071455 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.3 2.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 7.4 GO:0002347 response to tumor cell(GO:0002347)
0.3 1.8 GO:0043144 snoRNA processing(GO:0043144)
0.3 3.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.3 5.0 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 1.7 GO:0051013 microtubule severing(GO:0051013)
0.2 5.9 GO:0015701 bicarbonate transport(GO:0015701)
0.2 3.0 GO:0072675 osteoclast fusion(GO:0072675)
0.2 2.8 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 6.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 1.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 1.4 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 5.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.2 1.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 2.1 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.2 1.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 5.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 16.0 GO:0045576 mast cell activation(GO:0045576)
0.2 9.6 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.2 1.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 1.5 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 1.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 5.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.0 GO:1900740 positive regulation of thymocyte apoptotic process(GO:0070245) regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 1.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 4.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 3.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 5.9 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 3.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 3.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 8.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.3 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.9 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.7 GO:0031179 peptide modification(GO:0031179)
0.1 5.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 3.1 GO:0010107 potassium ion import(GO:0010107)
0.1 1.6 GO:0007141 male meiosis I(GO:0007141)
0.1 0.7 GO:0007144 female meiosis I(GO:0007144)
0.1 0.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.2 GO:0097273 creatinine homeostasis(GO:0097273) cellular ammonia homeostasis(GO:0097275) cellular creatinine homeostasis(GO:0097276) cellular urea homeostasis(GO:0097277)
0.1 2.8 GO:0000578 embryonic axis specification(GO:0000578)
0.1 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 1.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.9 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 2.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.8 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 2.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.0 GO:0001553 luteinization(GO:0001553)
0.0 3.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 14.5 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.3 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 4.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.7 GO:0036398 TCR signalosome(GO:0036398)
4.8 28.9 GO:0097149 centralspindlin complex(GO:0097149)
4.1 12.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.5 7.4 GO:0005588 collagen type V trimer(GO:0005588)
1.8 28.2 GO:0042555 MCM complex(GO:0042555)
1.1 3.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.9 4.5 GO:0035976 AP1 complex(GO:0035976)
0.8 55.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.7 9.6 GO:0097427 microtubule bundle(GO:0097427)
0.7 2.7 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.6 6.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.6 5.6 GO:0061689 tricellular tight junction(GO:0061689)
0.5 3.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 2.3 GO:0044307 dendritic branch(GO:0044307)
0.4 5.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 3.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 5.1 GO:0031209 SCAR complex(GO:0031209)
0.3 2.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 4.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 4.8 GO:0031143 pseudopodium(GO:0031143)
0.2 0.7 GO:0005712 chiasma(GO:0005712)
0.2 4.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 8.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 5.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 4.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 12.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.0 GO:0033391 chromatoid body(GO:0033391)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.0 GO:0031673 H zone(GO:0031673)
0.1 2.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0034657 GID complex(GO:0034657)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 5.0 GO:0031519 PcG protein complex(GO:0031519)
0.1 7.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 4.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 7.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 15.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 19.7 GO:0000790 nuclear chromatin(GO:0000790)
0.1 10.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 25.2 GO:0016607 nuclear speck(GO:0016607)
0.1 3.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.6 GO:0030057 desmosome(GO:0030057)
0.0 60.7 GO:0009986 cell surface(GO:0009986)
0.0 3.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.8 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 1.9 GO:0031430 M band(GO:0031430)
0.0 9.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 8.6 GO:0005769 early endosome(GO:0005769)
0.0 13.0 GO:0031252 cell leading edge(GO:0031252)
0.0 2.5 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0010008 endosome membrane(GO:0010008)
0.0 4.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 26.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
3.8 23.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
3.6 10.8 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
2.3 9.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
2.1 6.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.1 7.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.0 7.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.0 5.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.0 55.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.8 4.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.8 3.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.7 8.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.7 6.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 28.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 6.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 9.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 2.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.5 1.6 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.5 3.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.5 3.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 7.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 5.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.5 1.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 1.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 4.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 2.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4 5.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 1.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 3.3 GO:0005499 vitamin D binding(GO:0005499)
0.4 3.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.4 2.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 4.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 1.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 12.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 6.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 13.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 3.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 2.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 4.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 5.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 6.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 1.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.3 4.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 40.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 14.2 GO:0070888 E-box binding(GO:0070888)
0.2 6.1 GO:0070410 co-SMAD binding(GO:0070410)
0.2 2.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 2.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 2.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 3.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 0.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 2.1 GO:0071253 connexin binding(GO:0071253)
0.2 1.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.2 7.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 12.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 5.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.4 GO:0048156 tau protein binding(GO:0048156)
0.1 3.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 8.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.0 GO:0009881 photoreceptor activity(GO:0009881)
0.1 11.3 GO:0005178 integrin binding(GO:0005178)
0.1 4.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 3.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.8 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 0.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 3.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 3.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 13.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 7.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 7.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 10.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 16.0 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 2.0 GO:0030507 spectrin binding(GO:0030507)
0.0 1.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.0 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 29.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.9 67.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.7 12.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 10.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.5 30.4 PID PLK1 PATHWAY PLK1 signaling events
0.5 24.6 PID ATR PATHWAY ATR signaling pathway
0.4 3.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.4 5.7 PID IL5 PATHWAY IL5-mediated signaling events
0.3 14.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 10.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 5.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 20.7 PID E2F PATHWAY E2F transcription factor network
0.3 12.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 14.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 5.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 3.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 3.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 5.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 6.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 7.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 13.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.8 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 6.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 9.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 9.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 29.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.2 PID FOXO PATHWAY FoxO family signaling
0.1 2.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 5.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 14.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 9.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 28.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 55.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.8 10.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.8 11.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.7 29.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 19.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5 10.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 9.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 7.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 9.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.4 4.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.3 28.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 6.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 11.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 6.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 12.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 6.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 0.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 5.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.2 3.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 3.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 7.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 5.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 5.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 4.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 8.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 6.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 6.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 11.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.8 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 3.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 4.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME MEIOSIS Genes involved in Meiosis
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis