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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxd2

Z-value: 0.63

Motif logo

Transcription factors associated with Foxd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000055210.5 Foxd2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd2mm39_v1_chr4_-_114766070_1147661110.132.7e-01Click!

Activity profile of Foxd2 motif

Sorted Z-values of Foxd2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_173105344 8.57 ENSMUST00000111224.5
mucosal pentraxin 2
chr7_+_130633776 6.92 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr1_+_174158083 6.87 ENSMUST00000027816.5
mucosal pentraxin 1
chr3_-_144738526 4.75 ENSMUST00000029919.7
chloride channel accessory 1
chr2_-_62313981 4.22 ENSMUST00000136686.2
ENSMUST00000102733.10
glucagon
chr7_+_97480125 4.16 ENSMUST00000206351.2
p21 (RAC1) activated kinase 1
chr3_-_72875187 3.71 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr18_+_37637317 3.46 ENSMUST00000052179.8
protocadherin beta 20
chr2_+_14393127 3.42 ENSMUST00000114731.8
ENSMUST00000082290.8
solute carrier family 39 (zinc transporter), member 12
chr16_+_13804461 3.21 ENSMUST00000056521.12
ENSMUST00000118412.8
ENSMUST00000131608.2
bMERB domain containing 1
chr17_-_37334091 3.21 ENSMUST00000167275.3
myelin oligodendrocyte glycoprotein
chr3_-_144511566 3.14 ENSMUST00000199029.2
chloride channel accessory 3A2
chr9_+_50466127 2.83 ENSMUST00000213916.2
interleukin 18
chr17_+_29309942 2.78 ENSMUST00000119901.9
cyclin-dependent kinase inhibitor 1A (P21)
chr10_+_42736771 2.64 ENSMUST00000105494.8
Scm polycomb group protein like 4
chr3_+_75982890 2.61 ENSMUST00000160261.8
follistatin-like 5
chr17_+_34311314 2.61 ENSMUST00000025192.8
histocompatibility 2, O region alpha locus
chr10_-_18887701 2.60 ENSMUST00000105527.2
tumor necrosis factor, alpha-induced protein 3
chr2_-_110591909 2.51 ENSMUST00000140777.2
anoctamin 3
chr7_+_91321500 2.39 ENSMUST00000238619.2
ENSMUST00000238467.2
discs large MAGUK scaffold protein 2
chr12_-_41536430 2.33 ENSMUST00000043884.6
leucine rich repeat protein 3, neuronal
chr15_-_98505508 2.20 ENSMUST00000096224.6
adenylate cyclase 6
chr1_-_37535202 2.17 ENSMUST00000143636.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr14_+_80237691 2.15 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr7_+_91321694 2.05 ENSMUST00000238608.2
discs large MAGUK scaffold protein 2
chr13_-_95170755 1.95 ENSMUST00000162670.8
phosphodiesterase 8B
chr12_+_38833501 1.87 ENSMUST00000159334.8
ets variant 1
chr18_-_6516089 1.85 ENSMUST00000115870.9
enhancer of polycomb homolog 1
chrX_+_162922317 1.80 ENSMUST00000112271.10
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr14_-_70867588 1.75 ENSMUST00000228009.2
dematin actin binding protein
chr12_+_38833454 1.73 ENSMUST00000161980.8
ENSMUST00000160701.8
ets variant 1
chr10_-_128579879 1.73 ENSMUST00000026414.9
diacylglycerol kinase, alpha
chr5_+_107645626 1.72 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr4_-_136626073 1.71 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr2_+_14393245 1.69 ENSMUST00000133258.2
solute carrier family 39 (zinc transporter), member 12
chr14_+_102077937 1.69 ENSMUST00000159026.8
LIM domain only 7
chr18_+_73996743 1.68 ENSMUST00000134847.2
maestro
chr9_+_36744016 1.66 ENSMUST00000214772.2
fasciculation and elongation protein zeta 1 (zygin I)
chr15_+_100052260 1.65 ENSMUST00000023768.14
disco interacting protein 2 homolog B
chr1_-_37535170 1.63 ENSMUST00000148047.2
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chrX_+_158480304 1.60 ENSMUST00000123433.8
SH3-domain kinase binding protein 1
chr16_-_16345197 1.56 ENSMUST00000069284.14
FYVE, RhoGEF and PH domain containing 4
chr2_-_104241358 1.54 ENSMUST00000230671.2
RIKEN cDNA D430041D05 gene
chr1_+_107456731 1.51 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chrX_-_104973003 1.50 ENSMUST00000130980.2
ENSMUST00000113573.8
ATRX, chromatin remodeler
chr14_+_102078038 1.50 ENSMUST00000159314.8
LIM domain only 7
chrX_-_104972938 1.48 ENSMUST00000198448.5
ENSMUST00000199233.5
ENSMUST00000134507.8
ENSMUST00000154866.8
ENSMUST00000128968.8
ENSMUST00000134381.8
ENSMUST00000150914.8
ATRX, chromatin remodeler
chr14_+_54113415 1.47 ENSMUST00000180938.3
T cell receptor alpha variable 21-DV12
chr11_+_78811613 1.47 ENSMUST00000018610.7
nitric oxide synthase 2, inducible
chr11_+_97692738 1.46 ENSMUST00000127033.9
LIM and SH3 protein 1
chr6_+_77219627 1.41 ENSMUST00000159616.2
leucine rich repeat transmembrane neuronal 1
chr13_-_97235745 1.40 ENSMUST00000071118.7
predicted gene 6169
chr6_+_77219698 1.39 ENSMUST00000161677.2
leucine rich repeat transmembrane neuronal 1
chr1_-_80687213 1.39 ENSMUST00000186087.7
dedicator of cytokinesis 10
chr6_+_38895902 1.36 ENSMUST00000003017.13
thromboxane A synthase 1, platelet
chr5_-_23889607 1.33 ENSMUST00000197985.5
serine/arginine-rich protein specific kinase 2
chr5_+_148202011 1.32 ENSMUST00000110515.9
microtubule associated tumor suppressor candidate 2
chr16_-_45313244 1.30 ENSMUST00000232138.2
predicted gene 609
chr3_+_7494108 1.30 ENSMUST00000193330.2
protein kinase inhibitor, alpha
chr16_-_45313324 1.30 ENSMUST00000114585.3
predicted gene 609
chrX_+_136552469 1.26 ENSMUST00000075471.4
interleukin 1 receptor accessory protein-like 2
chr5_-_120750623 1.25 ENSMUST00000140554.2
ENSMUST00000031599.9
ENSMUST00000177800.8
RBPJ interacting and tubulin associated 1
chr18_+_37646674 1.24 ENSMUST00000061405.6
protocadherin beta 21
chr5_-_103247920 1.23 ENSMUST00000112848.8
mitogen-activated protein kinase 10
chr2_+_24235300 1.21 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr15_-_101833160 1.19 ENSMUST00000023797.8
keratin 4
chr16_+_48637219 1.19 ENSMUST00000023328.8
resistin like beta
chr2_+_124978518 1.18 ENSMUST00000238754.2
cortexin 2
chr7_+_43284131 1.17 ENSMUST00000032663.10
carcinoembryonic antigen-related cell adhesion molecule 18
chrX_-_104972844 1.16 ENSMUST00000198441.5
ENSMUST00000137453.8
ATRX, chromatin remodeler
chr5_-_110220379 1.13 ENSMUST00000210275.2
predicted gene, 17655
chr18_+_37858753 1.12 ENSMUST00000066149.9
protocadherin gamma subfamily A, 8
chr3_-_75177378 1.09 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr3_-_123483772 1.08 ENSMUST00000172537.3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_-_25498459 1.08 ENSMUST00000058137.9
RAB, member RAS oncogene family-like 6
chr2_+_124978612 1.07 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr10_-_116732813 1.06 ENSMUST00000048229.9
myelin regulatory factor-like
chr5_+_148202117 0.98 ENSMUST00000110514.8
microtubule associated tumor suppressor candidate 2
chr2_+_132532040 0.97 ENSMUST00000148271.8
ENSMUST00000110132.3
shieldin complex subunit 1
chr1_+_171668173 0.94 ENSMUST00000136479.8
CD84 antigen
chr9_+_94551929 0.94 ENSMUST00000033463.10
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr5_+_32404695 0.92 ENSMUST00000101376.3
phospholipase B1
chr3_+_114874614 0.88 ENSMUST00000051309.9
olfactomedin 3
chr5_+_20433169 0.87 ENSMUST00000197553.5
ENSMUST00000208219.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_75368532 0.87 ENSMUST00000143539.8
ENSMUST00000134114.8
lymphocyte cytosolic protein 1
chr18_+_89224219 0.85 ENSMUST00000236835.2
CD226 antigen
chr10_-_10956700 0.83 ENSMUST00000105560.2
glutamate receptor, metabotropic 1
chr7_+_105290259 0.83 ENSMUST00000209445.2
translocase of inner mitochondrial membrane 10B
chr11_+_98689479 0.81 ENSMUST00000037930.13
male specific lethal 1
chr11_-_107080150 0.76 ENSMUST00000106757.8
ENSMUST00000018577.8
nucleolar protein 11
chr10_-_88440869 0.76 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr17_-_35265702 0.76 ENSMUST00000097338.11
mutS homolog 5
chr18_+_68470616 0.74 ENSMUST00000172148.4
ENSMUST00000239469.2
melanocortin 5 receptor
chr17_+_8144822 0.74 ENSMUST00000036370.8
T cell activation Rho GTPase activating protein
chr9_+_96140781 0.73 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
transcription factor Dp 2
chr5_-_87845916 0.73 ENSMUST00000196163.2
casein beta
chr10_+_57521958 0.72 ENSMUST00000177473.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr19_-_53577499 0.69 ENSMUST00000095978.5
nuclear transport factor 2, pseudogene 1
chr6_-_129600798 0.67 ENSMUST00000095412.10
killer cell lectin-like receptor subfamily K, member 1
chr5_+_18167547 0.64 ENSMUST00000030561.9
guanine nucleotide binding protein, alpha transducing 3
chr5_+_148202075 0.60 ENSMUST00000071878.12
microtubule associated tumor suppressor candidate 2
chr7_-_108769719 0.59 ENSMUST00000208136.2
ENSMUST00000036992.9
LIM domain only 1
chr6_-_57827328 0.59 ENSMUST00000203310.3
ENSMUST00000203488.3
vomeronasal 1 receptor 21
chr13_-_98152768 0.56 ENSMUST00000238746.2
Rho guanine nucleotide exchange factor (GEF) 28
chrX_-_100312629 0.56 ENSMUST00000117736.2
predicted gene 20489
chr6_+_17636979 0.56 ENSMUST00000015877.14
ENSMUST00000152005.3
capping protein (actin filament) muscle Z-line, alpha 2
chr7_-_126795096 0.55 ENSMUST00000206026.2
ENSMUST00000205321.2
ENSMUST00000206587.2
ENSMUST00000205316.2
ENSMUST00000166791.8
CD2 cytoplasmic tail binding protein 2
chr7_-_126795040 0.55 ENSMUST00000035771.5
CD2 cytoplasmic tail binding protein 2
chr4_-_45108038 0.55 ENSMUST00000107809.9
ENSMUST00000107808.3
ENSMUST00000107807.2
ENSMUST00000107810.3
translocase of outer mitochondrial membrane 5
chr5_+_149601688 0.54 ENSMUST00000100404.6
beta-3-glucosyltransferase
chr2_-_87881473 0.54 ENSMUST00000183862.3
olfactory receptor 1162
chr14_+_75368939 0.52 ENSMUST00000125833.8
ENSMUST00000124499.8
lymphocyte cytosolic protein 1
chr4_+_115594918 0.52 ENSMUST00000106525.9
EF-hand calcium binding domain 14
chr3_+_89427458 0.51 ENSMUST00000000811.8
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_+_11926757 0.50 ENSMUST00000133776.2
PHD finger protein 14
chr6_+_142244145 0.50 ENSMUST00000041993.3
islet amyloid polypeptide
chr1_+_171238873 0.49 ENSMUST00000159207.8
ENSMUST00000161241.8
upstream transcription factor 1
chr4_+_115594951 0.49 ENSMUST00000106522.9
EF-hand calcium binding domain 14
chr6_-_129600812 0.48 ENSMUST00000168919.8
killer cell lectin-like receptor subfamily K, member 1
chr1_-_173018204 0.48 ENSMUST00000215878.2
ENSMUST00000201132.3
olfactory receptor 1406
chr19_-_8691460 0.47 ENSMUST00000206560.2
ENSMUST00000205538.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr4_+_128621378 0.47 ENSMUST00000106079.10
ENSMUST00000133439.8
polyhomeotic 2
chr13_-_20008397 0.45 ENSMUST00000222664.2
ENSMUST00000065335.3
G protein-coupled receptor 141
chr2_-_17465410 0.45 ENSMUST00000145492.2
nebulette
chr6_+_136495784 0.45 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr2_-_87868043 0.44 ENSMUST00000129056.3
olfactory receptor 73
chr2_-_125624754 0.44 ENSMUST00000053699.13
SECIS binding protein 2-like
chr14_+_54436898 0.42 ENSMUST00000103721.3
T cell receptor alpha joining 20
chr1_-_58009191 0.42 ENSMUST00000159826.2
ENSMUST00000164963.8
potassium channel tetramerisation domain containing 18
chr2_-_111779785 0.41 ENSMUST00000099604.6
olfactory receptor 1307
chr2_+_87853118 0.41 ENSMUST00000214438.2
olfactory receptor 1161
chr7_+_6346723 0.41 ENSMUST00000207173.3
predicted gene 3854
chr3_-_14676261 0.40 ENSMUST00000108365.4
ribosomal biogenesis factor
chr9_+_37995368 0.38 ENSMUST00000212502.4
olfactory receptor 887
chr4_+_108576846 0.38 ENSMUST00000178992.2
RIKEN cDNA 3110021N24 gene
chr9_+_78016468 0.38 ENSMUST00000118869.8
ENSMUST00000125615.2
ciliogenesis associated kinase 1
chr6_-_3494587 0.37 ENSMUST00000049985.15
HEPACAM family member 2
chrX_+_106192510 0.37 ENSMUST00000147521.8
ENSMUST00000167673.2
purinergic receptor P2Y, G-protein coupled 10B
chr7_+_28834276 0.37 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
RAS guanyl releasing protein 4
chrX_-_50031587 0.36 ENSMUST00000060650.7
FERM domain containing 7
chr7_+_140226365 0.36 ENSMUST00000084456.6
ENSMUST00000211057.2
ENSMUST00000211399.2
olfactory receptor 53
chr11_+_29413734 0.35 ENSMUST00000155854.8
coiled coil domain containing 88A
chr12_-_101924407 0.35 ENSMUST00000159883.2
ENSMUST00000160251.8
ENSMUST00000161011.8
ENSMUST00000021606.12
ataxin 3
chr10_+_66932235 0.34 ENSMUST00000174317.8
jumonji domain containing 1C
chr2_-_86061745 0.33 ENSMUST00000216056.2
olfactory receptor 1047
chr10_-_88440996 0.32 ENSMUST00000121629.8
myosin binding protein C, slow-type
chr12_+_65122355 0.32 ENSMUST00000058889.5
Fanconi anemia, complementation group M
chr6_-_57992144 0.32 ENSMUST00000228070.2
ENSMUST00000228040.2
vomeronasal 1 receptor 26
chr6_+_132824105 0.32 ENSMUST00000071696.2
taste receptor, type 2, member 123
chr9_+_96140750 0.31 ENSMUST00000186609.7
transcription factor Dp 2
chr1_-_58009263 0.29 ENSMUST00000114410.10
potassium channel tetramerisation domain containing 18
chr17_-_37625328 0.29 ENSMUST00000169373.2
olfactory receptor 102
chr9_-_20791012 0.29 ENSMUST00000043726.8
angiopoietin-like 6
chr2_+_111198936 0.29 ENSMUST00000090328.5
olfactory receptor 1283
chr9_+_38340751 0.29 ENSMUST00000216502.3
ENSMUST00000216644.2
olfactory receptor 901
chr2_-_11608003 0.29 ENSMUST00000040314.12
RNA binding motif protein 17
chr5_+_87955941 0.29 ENSMUST00000072539.12
ENSMUST00000113279.8
ENSMUST00000101057.8
ENSMUST00000197301.2
casein alpha s2-like B
chr7_-_102804952 0.28 ENSMUST00000061055.2
olfactory receptor 589
chrX_+_82898974 0.28 ENSMUST00000239269.2
dystrophin, muscular dystrophy
chr11_+_58549642 0.26 ENSMUST00000214392.2
olfactory receptor 322
chr1_-_157084252 0.24 ENSMUST00000134543.8
RAS protein activator like 2
chr14_-_50380137 0.23 ENSMUST00000213685.2
olfactory receptor 728
chr2_+_120807498 0.23 ENSMUST00000067582.14
transmembrane protein 62
chrX_+_108240356 0.21 ENSMUST00000139259.2
ENSMUST00000060013.4
predicted gene 6377
chrX_+_132751729 0.21 ENSMUST00000033602.9
tenomodulin
chr16_-_19132814 0.21 ENSMUST00000216157.2
olfactory receptor 164
chr14_+_53270305 0.20 ENSMUST00000179512.3
T cell receptor alpha variable 13D-3
chr5_-_87847268 0.20 ENSMUST00000196869.5
ENSMUST00000199624.5
ENSMUST00000198057.5
ENSMUST00000082370.10
casein beta
chr7_-_102143980 0.17 ENSMUST00000058750.4
olfactory receptor 545
chr10_+_57521930 0.17 ENSMUST00000177325.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr7_-_13723513 0.17 ENSMUST00000165167.8
ENSMUST00000108520.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr2_-_87504008 0.16 ENSMUST00000213835.2
olfactory receptor 1135
chr5_-_86475595 0.16 ENSMUST00000122377.2
transmembrane protease, serine 11d
chr7_-_103113358 0.15 ENSMUST00000214347.2
olfactory receptor 607
chr4_-_130033152 0.15 ENSMUST00000119423.8
hypocretin (orexin) receptor 1
chr17_-_56583715 0.14 ENSMUST00000058136.9
toll-like receptor adaptor molecule 1
chr6_-_54949587 0.13 ENSMUST00000060655.15
nucleotide-binding oligomerization domain containing 1
chr1_-_118239146 0.13 ENSMUST00000027623.9
translin
chr9_+_37683153 0.11 ENSMUST00000215128.2
olfactory receptor 875
chr2_-_86008164 0.11 ENSMUST00000215171.2
olfactory receptor 1044
chr18_-_62729391 0.10 ENSMUST00000076194.6
serine peptidase inhibitor, Kazal type 7 (putative)
chr1_-_170695328 0.10 ENSMUST00000027974.7
activating transcription factor 6
chr4_-_82768958 0.09 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chr9_-_95632387 0.08 ENSMUST00000189137.7
ENSMUST00000053785.10
transient receptor potential cation channel, subfamily C, member 1
chr17_+_38110779 0.07 ENSMUST00000215168.2
ENSMUST00000216478.2
olfactory receptor 124
chr2_-_109111064 0.05 ENSMUST00000147770.2
methyltransferase like 15
chr2_+_164674782 0.04 ENSMUST00000103093.10
cathepsin A
chr10_-_89457115 0.03 ENSMUST00000020102.14
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr9_+_7628201 0.03 ENSMUST00000034487.4
matrix metallopeptidase 20 (enamelysin)
chr2_+_36886739 0.03 ENSMUST00000069578.5
olfactory receptor 357
chr12_-_111946560 0.02 ENSMUST00000190680.2
retinal degeneration 3-like
chr16_+_84590434 0.02 ENSMUST00000231910.2
junction adhesion molecule 2
chr11_+_95227836 0.01 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr2_+_164674801 0.01 ENSMUST00000103092.9
ENSMUST00000151493.3
ENSMUST00000127650.8
cathepsin A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.9 2.6 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 2.6 GO:0002632 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.7 2.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.7 2.8 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.7 4.1 GO:0097394 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.5 4.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 1.8 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.4 1.2 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.3 0.9 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.3 2.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.3 1.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.3 5.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 6.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.9 GO:0035106 operant conditioning(GO:0035106)
0.2 1.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.9 GO:1903487 regulation of lactation(GO:1903487)
0.2 1.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 4.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 3.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 2.8 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 1.6 GO:0030035 microspike assembly(GO:0030035)
0.2 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.9 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 2.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 1.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 2.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 7.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.9 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 1.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.5 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.5 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.5 GO:0060356 leucine import(GO:0060356)
0.1 1.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.3 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.1 1.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.9 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 1.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.5 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 2.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 7.0 GO:0007416 synapse assembly(GO:0007416)
0.0 2.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 3.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0002606 regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 4.1 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.5 6.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 0.8 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 4.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 4.2 GO:0071437 invadopodium(GO:0071437)
0.1 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 4.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.2 GO:0042581 specific granule(GO:0042581)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 2.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.8 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 2.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 6.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.9 GO:0005903 brush border(GO:0005903)
0.0 2.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.2 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0030027 lamellipodium(GO:0030027)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0035375 zymogen binding(GO:0035375)
0.9 3.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.9 2.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 4.1 GO:0015616 DNA translocase activity(GO:0015616)
0.4 1.2 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.4 3.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 1.5 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.3 3.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 10.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 2.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 1.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3 0.9 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.3 1.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 1.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 0.8 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 4.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 4.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 5.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 3.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.4 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 7.5 GO:0050839 cell adhesion molecule binding(GO:0050839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 3.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 6.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 4.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.8 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.0 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions