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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxg1

Z-value: 0.45

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Transcription factors associated with Foxg1

Gene Symbol Gene ID Gene Info
Foxg1
ENSMUSG00000020950.11 Foxg1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxg1mm39_v1_chr12_+_49429790_494298880.381.2e-03Click!

Activity profile of Foxg1 motif

Sorted Z-values of Foxg1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxg1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_106057077 3.24 ENSMUST00000149836.2
Chil3
chitinase-like 3
chr2_-_154400753 2.24 ENSMUST00000109716.9
ENSMUST00000000895.13
ENSMUST00000125793.2
Necab3
N-terminal EF-hand calcium binding protein 3
chr15_+_79775894 2.14 ENSMUST00000177483.8
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr7_+_142558783 2.09 ENSMUST00000009396.13
Tspan32
tetraspanin 32
chr8_+_112263465 1.92 ENSMUST00000095176.12
Znrf1
zinc and ring finger 1
chr7_+_142558837 1.87 ENSMUST00000207211.2
Tspan32
tetraspanin 32
chr4_+_155045372 1.74 ENSMUST00000049621.7
Hes5
hes family bHLH transcription factor 5
chr15_+_79775819 1.70 ENSMUST00000177350.8
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr8_+_112263632 1.69 ENSMUST00000173506.8
Znrf1
zinc and ring finger 1
chr3_-_50398027 1.65 ENSMUST00000029297.6
ENSMUST00000194462.6
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr1_-_79838897 1.44 ENSMUST00000190724.2
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr8_+_112262729 1.38 ENSMUST00000172856.8
Znrf1
zinc and ring finger 1
chr2_+_120331784 1.31 ENSMUST00000151342.3
Capn3
calpain 3
chr8_+_112263255 1.31 ENSMUST00000171182.8
ENSMUST00000168428.8
Znrf1
zinc and ring finger 1
chr2_-_152672535 1.29 ENSMUST00000146380.2
ENSMUST00000134902.2
ENSMUST00000134357.2
ENSMUST00000109820.5
Bcl2l1
BCL2-like 1
chr18_+_68433422 1.28 ENSMUST00000009679.11
ENSMUST00000131075.8
ENSMUST00000025427.14
ENSMUST00000139111.2
Rnmt
RNA (guanine-7-) methyltransferase
chr9_+_13298301 1.18 ENSMUST00000159294.9
Maml2
mastermind like transcriptional coactivator 2
chr13_+_34346936 1.18 ENSMUST00000124996.8
ENSMUST00000147632.3
Psmg4
proteasome (prosome, macropain) assembly chaperone 4
chr18_+_73992446 1.11 ENSMUST00000120033.8
ENSMUST00000179472.8
ENSMUST00000119239.8
Mro
maestro
chr3_+_84081411 1.07 ENSMUST00000193882.2
Gm6525
predicted pseudogene 6525
chr5_+_34527230 1.03 ENSMUST00000180376.8
Fam193a
family with sequence homology 193, member A
chr11_-_119932573 1.02 ENSMUST00000103019.2
Aatk
apoptosis-associated tyrosine kinase
chr5_-_142892457 0.95 ENSMUST00000167721.8
ENSMUST00000163829.2
ENSMUST00000100497.11
Actb
actin, beta
chr11_-_97635484 0.90 ENSMUST00000018691.9
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr17_+_81251997 0.85 ENSMUST00000025092.5
Tmem178
transmembrane protein 178
chr12_-_112964279 0.84 ENSMUST00000011302.9
Brf1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr15_-_85466009 0.84 ENSMUST00000023015.15
Wnt7b
wingless-type MMTV integration site family, member 7B
chr7_+_79848138 0.77 ENSMUST00000205822.2
Sema4b
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_72322116 0.76 ENSMUST00000070345.5
Usp39
ubiquitin specific peptidase 39
chr1_-_180641159 0.70 ENSMUST00000162118.8
ENSMUST00000159685.2
ENSMUST00000161308.8
H3f3a
H3.3 histone A
chr8_+_46616688 0.69 ENSMUST00000034048.13
ENSMUST00000145229.2
Cfap97
cilia and flagella associated protein 97
chr15_+_103148824 0.69 ENSMUST00000036004.16
ENSMUST00000087351.9
ENSMUST00000231141.2
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
chr8_+_46616770 0.62 ENSMUST00000110376.8
Cfap97
cilia and flagella associated protein 97
chr6_-_129694095 0.57 ENSMUST00000088046.2
Klri1
killer cell lectin-like receptor family I member 1
chr9_+_106048116 0.54 ENSMUST00000020490.13
Wdr82
WD repeat domain containing 82
chr15_+_66449385 0.52 ENSMUST00000230882.2
ENSMUST00000048188.10
ENSMUST00000230948.2
ENSMUST00000229160.2
Phf20l1
PHD finger protein 20-like 1
chr7_+_75498058 0.47 ENSMUST00000171155.4
ENSMUST00000092073.11
ENSMUST00000206019.2
ENSMUST00000205612.2
ENSMUST00000205887.2
Klhl25
kelch-like 25
chr8_+_84793453 0.47 ENSMUST00000211046.2
ENSMUST00000005600.6
Rfx1
regulatory factor X, 1 (influences HLA class II expression)
chr2_+_4394425 0.41 ENSMUST00000115037.9
Frmd4a
FERM domain containing 4A
chr16_+_88954838 0.41 ENSMUST00000062524.6
Gm9789
predicted gene 9789
chr4_-_108690805 0.40 ENSMUST00000102742.11
Btf3l4
basic transcription factor 3-like 4
chr3_-_94922525 0.39 ENSMUST00000128438.2
ENSMUST00000149747.2
ENSMUST00000019482.8
Zfp687
zinc finger protein 687
chr1_-_72914036 0.39 ENSMUST00000027377.9
Igfbp5
insulin-like growth factor binding protein 5
chr7_-_99345016 0.38 ENSMUST00000107086.9
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr1_-_160405464 0.37 ENSMUST00000238289.2
Gpr52
G protein-coupled receptor 52
chr1_-_180641099 0.30 ENSMUST00000159789.2
ENSMUST00000081026.11
H3f3a
H3.3 histone A
chr9_-_60557076 0.28 ENSMUST00000053171.14
Lrrc49
leucine rich repeat containing 49
chr5_-_106844396 0.28 ENSMUST00000137285.8
ENSMUST00000124263.2
ENSMUST00000112695.4
ENSMUST00000155495.8
ENSMUST00000135108.2
ENSMUST00000149128.3
Zfp644
Gm28039
zinc finger protein 644
predicted gene, 28039
chr1_+_82817170 0.26 ENSMUST00000189220.7
ENSMUST00000113444.8
Agfg1
ArfGAP with FG repeats 1
chr4_-_108690741 0.25 ENSMUST00000102740.8
ENSMUST00000102741.8
Btf3l4
basic transcription factor 3-like 4
chr1_+_82817388 0.24 ENSMUST00000190052.7
ENSMUST00000063380.11
ENSMUST00000187899.7
ENSMUST00000186302.7
ENSMUST00000190046.7
Agfg1
ArfGAP with FG repeats 1
chr7_-_99344832 0.21 ENSMUST00000145381.8
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr7_+_23085312 0.20 ENSMUST00000086341.12
ENSMUST00000015866.14
Nlrp5
NLR family, pyrin domain containing 5
chr15_-_76116245 0.17 ENSMUST00000167754.8
Plec
plectin
chr14_+_43156329 0.15 ENSMUST00000228117.2
Gm9732
predicted gene 9732
chr2_-_162929732 0.15 ENSMUST00000094653.6
Gtsf1l
gametocyte specific factor 1-like
chr2_-_152673032 0.15 ENSMUST00000128172.3
Bcl2l1
BCL2-like 1
chr1_-_180641430 0.13 ENSMUST00000162814.8
H3f3a
H3.3 histone A
chr2_+_88479038 0.13 ENSMUST00000120518.4
Olfr1192-ps1
olfactory receptor 1192, pseudogene 1
chr3_-_127019496 0.08 ENSMUST00000182064.9
ENSMUST00000182452.8
Ank2
ankyrin 2, brain
chr1_-_120432477 0.06 ENSMUST00000186432.3
Marco
macrophage receptor with collagenous structure
chr2_+_28403255 0.05 ENSMUST00000028170.15
Ralgds
ral guanine nucleotide dissociation stimulator
chr4_+_141520923 0.04 ENSMUST00000097805.11
ENSMUST00000030747.11
ENSMUST00000153094.2
Casp9
caspase 9
chr5_-_121329385 0.04 ENSMUST00000054547.9
ENSMUST00000100770.9
Ptpn11
protein tyrosine phosphatase, non-receptor type 11
chr14_-_121935829 0.02 ENSMUST00000040700.9
ENSMUST00000212181.2
Dock9
dedicator of cytokinesis 9
chr2_+_121120070 0.00 ENSMUST00000094639.10
Map1a
microtubule-associated protein 1 A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.5 1.4 GO:0061107 seminal vesicle development(GO:0061107)
0.4 1.4 GO:0046898 response to cycloheximide(GO:0046898)
0.4 4.0 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.4 3.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.3 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.3 1.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2 0.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 2.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 3.8 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.2 1.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 1.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.6 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.4 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.8 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 6.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.3 1.1 GO:0001740 Barr body(GO:0001740)
0.1 2.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.8 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.6 3.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 1.0 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.8 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 5.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane