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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Foxo4

Z-value: 0.99

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Transcription factors associated with Foxo4

Gene Symbol Gene ID Gene Info
Foxo4
ENSMUSG00000042903.9 Foxo4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxo4mm39_v1_chrX_+_100298134_1002981860.343.1e-03Click!

Activity profile of Foxo4 motif

Sorted Z-values of Foxo4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_129854256 7.13 ENSMUST00000110299.3
Tgm3
transglutaminase 3, E polypeptide
chr10_-_127099183 6.84 ENSMUST00000099172.5
Kif5a
kinesin family member 5A
chr10_-_127098932 6.84 ENSMUST00000217895.2
Kif5a
kinesin family member 5A
chr17_+_26421919 5.03 ENSMUST00000122058.8
ENSMUST00000025020.6
Rgs11
regulator of G-protein signaling 11
chr7_+_91321694 4.73 ENSMUST00000238608.2
Dlg2
discs large MAGUK scaffold protein 2
chr2_+_176490405 4.21 ENSMUST00000118012.9
Gm14295
predicted gene 14295
chr19_+_10366753 4.18 ENSMUST00000169121.9
ENSMUST00000076968.11
ENSMUST00000235479.2
ENSMUST00000223586.2
ENSMUST00000235784.2
ENSMUST00000224135.3
ENSMUST00000225452.3
ENSMUST00000237366.2
Syt7
synaptotagmin VII
chrX_-_165368675 4.10 ENSMUST00000000412.3
Egfl6
EGF-like-domain, multiple 6
chr9_+_37450551 4.08 ENSMUST00000002008.7
ENSMUST00000215957.2
ENSMUST00000215271.2
Vsig2
V-set and immunoglobulin domain containing 2
chr2_+_176400121 3.99 ENSMUST00000108981.9
ENSMUST00000108980.9
Gm14305
predicted gene 14305
chr2_-_176328111 3.93 ENSMUST00000108990.9
ENSMUST00000119149.8
ENSMUST00000117267.2
Gm14308
predicted gene 14308
chr2_+_176692749 3.92 ENSMUST00000108975.9
ENSMUST00000156844.8
Gm14419
predicted gene 14419
chr2_-_177720218 3.87 ENSMUST00000108924.9
ENSMUST00000131702.8
ENSMUST00000108923.2
Zfp931
zinc finger protein 931
chr2_-_177599032 3.84 ENSMUST00000108928.2
ENSMUST00000108932.8
ENSMUST00000108930.9
Gm14326
predicted gene 14326
chr2_-_151474391 3.82 ENSMUST00000137936.2
ENSMUST00000146172.8
ENSMUST00000094456.10
ENSMUST00000148755.8
ENSMUST00000109875.8
ENSMUST00000028951.14
ENSMUST00000109877.10
Snph
syntaphilin
chr2_-_176178566 3.81 ENSMUST00000120959.8
ENSMUST00000120521.2
Gm14434
predicted gene 14434
chr2_-_175277575 3.80 ENSMUST00000152941.2
ENSMUST00000109045.9
Gm4724
predicted gene 4724
chr2_-_174983792 3.79 ENSMUST00000109062.8
ENSMUST00000109059.8
ENSMUST00000109060.8
Gm14399
predicted gene 14399
chr11_-_42073737 3.75 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_+_175661012 3.75 ENSMUST00000109011.8
Gm6710
predicted gene 6710
chr4_+_136011969 3.73 ENSMUST00000144217.8
Zfp46
zinc finger protein 46
chr2_-_177482111 3.69 ENSMUST00000108939.9
ENSMUST00000150650.2
Gm14325
predicted gene 14325
chr2_+_175757124 3.61 ENSMUST00000109007.8
ENSMUST00000174416.8
Gm2026
predicted gene 2026
chr18_+_11972277 3.60 ENSMUST00000171109.9
ENSMUST00000046948.10
Cables1
CDK5 and Abl enzyme substrate 1
chr2_+_32496957 3.50 ENSMUST00000113290.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr8_-_45863335 3.48 ENSMUST00000210996.2
ENSMUST00000209772.2
Tlr3
toll-like receptor 3
chr9_+_45230370 3.47 ENSMUST00000034597.8
Tmprss13
transmembrane protease, serine 13
chr3_-_122910662 3.44 ENSMUST00000051443.8
Synpo2
synaptopodin 2
chr2_-_176898214 3.42 ENSMUST00000108964.2
Gm14410
predicted gene 14410
chr2_-_175048692 3.26 ENSMUST00000109055.2
ENSMUST00000099028.10
ENSMUST00000109056.8
ENSMUST00000109058.9
Gm14391
predicted gene 14391
chr4_+_136012019 3.24 ENSMUST00000130223.8
Zfp46
zinc finger protein 46
chr8_-_45863572 3.20 ENSMUST00000209651.2
ENSMUST00000211370.2
ENSMUST00000034056.12
ENSMUST00000167106.3
Tlr3
toll-like receptor 3
chr18_+_37813286 3.11 ENSMUST00000192931.2
Pcdhgb1
protocadherin gamma subfamily B, 1
chr7_-_89166724 3.04 ENSMUST00000208888.2
Prss23
protease, serine 23
chr2_-_45001141 2.81 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr14_-_25903524 2.79 ENSMUST00000052286.16
Plac9a
placenta specific 9a
chr2_+_176362315 2.76 ENSMUST00000121956.8
ENSMUST00000108985.9
Zfp973
zinc finger protein 973
chr9_+_108925727 2.67 ENSMUST00000130366.2
Plxnb1
plexin B1
chrX_+_134786600 2.64 ENSMUST00000180025.8
ENSMUST00000148374.8
ENSMUST00000068755.14
Bhlhb9
basic helix-loop-helix domain containing, class B9
chr9_+_107784065 2.61 ENSMUST00000035203.9
Mst1r
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr14_+_31750946 2.60 ENSMUST00000022460.11
Galnt15
polypeptide N-acetylgalactosaminyltransferase 15
chr4_-_32950812 2.51 ENSMUST00000084750.8
ENSMUST00000084748.9
Ankrd6
ankyrin repeat domain 6
chr9_+_8900460 2.50 ENSMUST00000070463.10
ENSMUST00000098986.4
Pgr
progesterone receptor
chr5_-_91550853 2.50 ENSMUST00000121044.6
Btc
betacellulin, epidermal growth factor family member
chr2_+_175214229 2.43 ENSMUST00000131676.8
ENSMUST00000109048.3
ENSMUST00000109047.3
Zfp968
zinc finger protein 968
chr2_+_177665068 2.43 ENSMUST00000108925.10
ENSMUST00000108926.3
Zfp971
zinc finger protein 971
chr2_+_175311778 2.42 ENSMUST00000109042.10
ENSMUST00000109002.9
ENSMUST00000109043.9
ENSMUST00000143490.2
Zfp965
zinc finger protein 965
chr6_-_38101503 2.42 ENSMUST00000040259.8
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr12_+_75355082 2.38 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
Rhoj
ras homolog family member J
chr2_+_176212793 2.35 ENSMUST00000238585.2
ENSMUST00000238250.2
ENSMUST00000238206.2
ENSMUST00000108997.10
ENSMUST00000238365.2
ENSMUST00000238420.2
ENSMUST00000178443.2
Zfp967
zinc finger protein 967
chr2_-_175179990 2.34 ENSMUST00000121393.9
Gm4631
predicted gene 4631
chr3_+_107803225 2.31 ENSMUST00000172247.8
ENSMUST00000167387.8
Gstm5
glutathione S-transferase, mu 5
chr18_-_39051695 2.28 ENSMUST00000040647.11
Fgf1
fibroblast growth factor 1
chr2_-_45000389 2.15 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr19_-_31641770 2.02 ENSMUST00000073581.6
Prkg1
protein kinase, cGMP-dependent, type I
chr2_-_175722844 2.01 ENSMUST00000108949.3
ENSMUST00000109018.3
Zfp966
zinc finger protein 966
chr5_-_135573962 1.86 ENSMUST00000060311.12
Hip1
huntingtin interacting protein 1
chr12_+_3945467 1.86 ENSMUST00000172749.2
Dnmt3a
DNA methyltransferase 3A
chr12_-_17379348 1.85 ENSMUST00000153090.8
ENSMUST00000143131.2
Atp6v1c2
ATPase, H+ transporting, lysosomal V1 subunit C2
chr19_+_20470114 1.84 ENSMUST00000225313.2
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr3_+_107803563 1.83 ENSMUST00000169365.2
Gstm5
glutathione S-transferase, mu 5
chr2_-_175495439 1.71 ENSMUST00000109027.9
ENSMUST00000179061.8
ENSMUST00000131041.2
Zfp969
zinc finger protein 969
chr1_+_6557455 1.68 ENSMUST00000140079.8
ENSMUST00000131494.8
St18
suppression of tumorigenicity 18
chr7_+_29003363 1.67 ENSMUST00000108231.8
Dpf1
D4, zinc and double PHD fingers family 1
chr1_+_131678223 1.66 ENSMUST00000147800.2
Slc26a9
solute carrier family 26, member 9
chr4_-_130253703 1.64 ENSMUST00000134159.3
Zcchc17
zinc finger, CCHC domain containing 17
chr7_-_78228116 1.58 ENSMUST00000206268.2
ENSMUST00000039431.14
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr13_-_91372072 1.56 ENSMUST00000022119.6
Atg10
autophagy related 10
chr5_+_92540444 1.55 ENSMUST00000126281.8
Art3
ADP-ribosyltransferase 3
chr15_-_77037756 1.52 ENSMUST00000227314.2
ENSMUST00000227930.2
ENSMUST00000227533.2
Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_128401832 1.52 ENSMUST00000203374.3
ENSMUST00000142615.4
ENSMUST00000001559.11
Itfg2
integrin alpha FG-GAP repeat containing 2
chr11_+_105480796 1.50 ENSMUST00000168598.8
ENSMUST00000100330.10
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr11_-_74238498 1.49 ENSMUST00000080365.6
Olfr411
olfactory receptor 411
chr8_-_47805383 1.36 ENSMUST00000110367.10
Stox2
storkhead box 2
chr7_+_29003382 1.36 ENSMUST00000049977.13
Dpf1
D4, zinc and double PHD fingers family 1
chr12_-_69939931 1.31 ENSMUST00000049239.8
ENSMUST00000110570.8
Map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr5_-_149559636 1.17 ENSMUST00000201452.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr8_+_84627332 1.17 ENSMUST00000045393.15
ENSMUST00000132500.8
ENSMUST00000152978.8
Adgrl1
adhesion G protein-coupled receptor L1
chr15_-_102533870 1.17 ENSMUST00000184485.8
ENSMUST00000185070.8
ENSMUST00000184616.8
ENSMUST00000108828.9
Atf7
activating transcription factor 7
chr10_+_60120259 1.15 ENSMUST00000165878.2
Psap
prosaposin
chr12_-_69939762 1.12 ENSMUST00000110567.8
ENSMUST00000171211.8
Map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_164024512 1.08 ENSMUST00000131974.2
Wfdc5
WAP four-disulfide core domain 5
chr13_-_117161921 1.05 ENSMUST00000223949.2
Parp8
poly (ADP-ribose) polymerase family, member 8
chr12_-_12990584 0.95 ENSMUST00000130990.2
Mycn
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
chr2_+_175968362 0.94 ENSMUST00000099009.9
ENSMUST00000136719.2
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr11_-_102470287 0.94 ENSMUST00000107081.8
Gm11627
predicted gene 11627
chr4_+_97665992 0.89 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
Nfia
nuclear factor I/A
chr5_-_149559737 0.88 ENSMUST00000200805.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr11_-_72097821 0.86 ENSMUST00000204457.3
Gm43951
predicted gene, 43951
chr15_-_102533494 0.82 ENSMUST00000184077.8
ENSMUST00000184906.8
ENSMUST00000169033.8
Atf7
activating transcription factor 7
chr4_-_82778066 0.78 ENSMUST00000107239.8
Zdhhc21
zinc finger, DHHC domain containing 21
chr2_-_119060366 0.76 ENSMUST00000076084.6
Ppp1r14d
protein phosphatase 1, regulatory inhibitor subunit 14D
chr15_-_35938155 0.74 ENSMUST00000156915.3
Cox6c
cytochrome c oxidase subunit 6C
chr7_-_3632826 0.73 ENSMUST00000205596.2
ENSMUST00000155592.8
ENSMUST00000108641.10
Tfpt
TCF3 (E2A) fusion partner
chr14_-_31807552 0.73 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
Dph3
diphthamine biosynthesis 3
chr2_-_176619602 0.68 ENSMUST00000099007.3
Gm14296
predicted gene 14296
chr14_+_31807760 0.57 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
Oxnad1
oxidoreductase NAD-binding domain containing 1
chr6_+_42263609 0.53 ENSMUST00000238845.2
ENSMUST00000031894.13
Clcn1
chloride channel, voltage-sensitive 1
chr19_-_53577499 0.50 ENSMUST00000095978.5
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr12_-_115129697 0.49 ENSMUST00000103524.2
ENSMUST00000193145.2
Ighv8-6
immunoglobulin heavy variable V8-6
chr15_-_35938328 0.46 ENSMUST00000014457.15
Cox6c
cytochrome c oxidase subunit 6C
chr15_-_77037926 0.45 ENSMUST00000228087.2
Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_+_122712809 0.41 ENSMUST00000075888.6
Zic2
zinc finger protein of the cerebellum 2
chr5_-_149559667 0.40 ENSMUST00000074846.14
Hsph1
heat shock 105kDa/110kDa protein 1
chr2_-_75768752 0.39 ENSMUST00000099996.5
Ttc30b
tetratricopeptide repeat domain 30B
chr13_-_117162041 0.38 ENSMUST00000022239.8
Parp8
poly (ADP-ribose) polymerase family, member 8
chr19_+_6391148 0.33 ENSMUST00000025897.13
ENSMUST00000130382.8
Map4k2
mitogen-activated protein kinase kinase kinase kinase 2
chr6_+_86986818 0.32 ENSMUST00000032060.15
ENSMUST00000117583.8
ENSMUST00000144776.7
Nfu1
NFU1 iron-sulfur cluster scaffold
chr8_-_34333573 0.28 ENSMUST00000183062.2
Rbpms
RNA binding protein gene with multiple splicing
chr11_-_76969230 0.26 ENSMUST00000102494.8
Nsrp1
nuclear speckle regulatory protein 1
chr12_+_83734919 0.22 ENSMUST00000041806.13
Psen1
presenilin 1
chr17_+_78815493 0.22 ENSMUST00000024880.11
ENSMUST00000232859.2
Vit
vitrin
chrX_+_133501928 0.21 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr2_+_181405106 0.20 ENSMUST00000081125.11
Myt1
myelin transcription factor 1
chr15_-_102533357 0.19 ENSMUST00000183765.2
Atf7
activating transcription factor 7
chr5_-_24650164 0.18 ENSMUST00000115043.8
ENSMUST00000115041.2
ENSMUST00000030800.13
Fastk
Fas-activated serine/threonine kinase
chr6_+_86986213 0.18 ENSMUST00000120240.8
Nfu1
NFU1 iron-sulfur cluster scaffold
chr2_-_44912927 0.15 ENSMUST00000202432.4
Zeb2
zinc finger E-box binding homeobox 2
chr19_+_20470056 0.13 ENSMUST00000225337.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chrX_-_133501874 0.12 ENSMUST00000033621.8
Gla
galactosidase, alpha
chrX_-_72080709 0.11 ENSMUST00000114540.4
ENSMUST00000051569.7
Pnma5
paraneoplastic antigen family 5
chr10_-_40133558 0.09 ENSMUST00000216847.2
ENSMUST00000213628.2
ENSMUST00000217537.2
ENSMUST00000019982.9
Gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr12_+_87313472 0.08 ENSMUST00000021425.8
Ahsa1
AHA1, activator of heat shock protein ATPase 1
chr2_+_85603057 0.07 ENSMUST00000213453.3
Olfr1014
olfactory receptor 1014
chr15_-_77480311 0.05 ENSMUST00000089465.6
Apol10b
apolipoprotein L 10B
chr19_-_24178000 0.04 ENSMUST00000233658.3
Tjp2
tight junction protein 2
chr16_-_19390500 0.01 ENSMUST00000215040.2
ENSMUST00000216070.2
ENSMUST00000215476.2
Olfr169
olfactory receptor 169

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.7 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
1.4 4.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.1 6.7 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.7 5.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.7 4.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.7 2.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.6 2.5 GO:1904708 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
0.5 1.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 1.9 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.4 2.0 GO:2000224 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224)
0.3 2.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 1.6 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.3 3.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 2.5 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.2 2.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 4.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 3.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 7.1 GO:0031424 keratinization(GO:0031424)
0.2 2.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 2.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 3.8 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 2.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 2.5 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 1.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 1.7 GO:0008272 sulfate transport(GO:0008272)
0.1 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 0.9 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 1.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 2.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 3.8 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 1.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 4.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 2.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 3.6 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.9 GO:0035253 ciliary rootlet(GO:0035253)
0.5 1.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 1.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 2.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 4.2 GO:0032009 early phagosome(GO:0032009)
0.2 5.0 GO:0044292 dendrite terminus(GO:0044292)
0.1 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 4.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 7.1 GO:0001533 cornified envelope(GO:0001533)
0.1 3.0 GO:0071565 nBAF complex(GO:0071565)
0.0 1.9 GO:0001741 XY body(GO:0001741)
0.0 5.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 6.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011)
0.0 8.2 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.0 2.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.7 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 3.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 13.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 2.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 3.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 2.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 4.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 5.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 4.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.6 GO:0005030 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.2 1.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 1.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 4.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 3.4 GO:0031005 filamin binding(GO:0031005)
0.1 5.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 4.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 6.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 46.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 3.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.6 PID SHP2 PATHWAY SHP2 signaling
0.0 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 PID FGF PATHWAY FGF signaling pathway
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 13.7 REACTOME KINESINS Genes involved in Kinesins
0.2 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 4.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 4.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 5.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases