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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Fubp1

Z-value: 0.82

Motif logo

Transcription factors associated with Fubp1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028034.16 Fubp1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fubp1mm39_v1_chr3_+_151916059_151916102-0.057.1e-01Click!

Activity profile of Fubp1 motif

Sorted Z-values of Fubp1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Fubp1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_110462446 6.12 ENSMUST00000033050.5
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_44508137 5.91 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
early B cell factor 1
chr6_+_17307639 5.65 ENSMUST00000115453.2
caveolin 1, caveolae protein
chr2_-_60503998 5.28 ENSMUST00000059888.15
ENSMUST00000154764.2
integrin beta 6
chr17_-_46343291 5.26 ENSMUST00000071648.12
ENSMUST00000142351.9
vascular endothelial growth factor A
chr11_-_106605772 5.16 ENSMUST00000124958.3
platelet/endothelial cell adhesion molecule 1
chr11_-_106606076 4.95 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
platelet/endothelial cell adhesion molecule 1
chr17_+_34423054 4.29 ENSMUST00000138491.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_97315465 4.17 ENSMUST00000105287.11
decorin
chr3_+_137046828 4.12 ENSMUST00000122064.8
ENSMUST00000119475.6
endomucin
chr3_+_137046935 3.99 ENSMUST00000197511.2
endomucin
chr5_-_69699965 3.78 ENSMUST00000031045.10
Yip1 domain family, member 7
chr16_-_94171340 3.72 ENSMUST00000138514.2
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_-_151960948 3.60 ENSMUST00000199423.5
ENSMUST00000198460.5
nexilin
chr3_-_151960992 3.35 ENSMUST00000198750.5
nexilin
chr5_-_69699932 3.26 ENSMUST00000202423.2
Yip1 domain family, member 7
chr4_+_94627755 3.22 ENSMUST00000071168.6
TEK receptor tyrosine kinase
chr15_-_5093222 3.00 ENSMUST00000110689.5
complement component 7
chr7_+_89053562 2.89 ENSMUST00000058755.5
frizzled class receptor 4
chr16_-_94171556 2.88 ENSMUST00000113906.9
phosphatidylinositol glycan anchor biosynthesis, class P
chr10_+_102348076 2.84 ENSMUST00000219445.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr11_+_67090878 2.81 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chrX_+_149377416 2.60 ENSMUST00000112713.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_97904958 2.54 ENSMUST00000161567.8
peptidylglycine alpha-amidating monooxygenase
chr1_-_138103021 2.54 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr6_+_29361408 2.48 ENSMUST00000156163.2
calumenin
chr16_-_94171533 2.43 ENSMUST00000113910.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr15_+_102862862 2.42 ENSMUST00000001701.4
homeobox C11
chr7_+_142014546 2.39 ENSMUST00000105968.8
ENSMUST00000018963.11
ENSMUST00000105967.8
lymphocyte specific 1
chr4_-_94538329 2.32 ENSMUST00000107101.2
leucine rich repeat containing 19
chr4_-_55532453 2.29 ENSMUST00000132746.2
ENSMUST00000107619.3
Kruppel-like factor 4 (gut)
chr6_+_48624295 2.27 ENSMUST00000078223.6
ENSMUST00000203509.2
GTPase, IMAP family member 8
chr11_-_68277799 2.23 ENSMUST00000135141.2
netrin 1
chr2_-_28806639 2.10 ENSMUST00000113847.3
BarH like homeobox 1
chr15_+_37233280 2.09 ENSMUST00000161405.8
ENSMUST00000022895.15
ENSMUST00000161532.2
grainyhead like transcription factor 2
chr13_+_112604037 2.05 ENSMUST00000183868.8
interleukin 6 signal transducer
chr4_-_94538370 2.05 ENSMUST00000053419.9
leucine rich repeat containing 19
chr1_-_138102972 2.04 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr3_-_157630690 2.02 ENSMUST00000118539.2
cystathionase (cystathionine gamma-lyase)
chr4_-_49549489 1.97 ENSMUST00000029987.10
aldolase B, fructose-bisphosphate
chr3_-_108934916 1.94 ENSMUST00000171143.2
family with sequence similarity 102, member B
chr14_+_51366512 1.93 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr1_-_134883645 1.87 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr6_-_122833109 1.86 ENSMUST00000042081.9
complement component 3a receptor 1
chr4_+_144619696 1.83 ENSMUST00000142808.8
dehydrogenase/reductase (SDR family) member 3
chr4_-_147726953 1.82 ENSMUST00000133006.2
ENSMUST00000037565.14
ENSMUST00000105720.8
zinc finger protein 979
chr7_-_70010341 1.79 ENSMUST00000032768.15
nuclear receptor subfamily 2, group F, member 2
chr10_+_94412116 1.77 ENSMUST00000117929.2
transmembrane and coiled coil domains 3
chr1_+_156193607 1.62 ENSMUST00000102782.4
predicted gene 2000
chr4_+_144619647 1.58 ENSMUST00000154208.8
dehydrogenase/reductase (SDR family) member 3
chr3_+_92192724 1.56 ENSMUST00000193337.2
small proline-rich protein 2A3
chrX_-_47602395 1.50 ENSMUST00000114945.9
ENSMUST00000037349.8
apoptosis-inducing factor, mitochondrion-associated 1
chrX_+_132809166 1.47 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr4_-_120682859 1.42 ENSMUST00000134979.8
ENSMUST00000136236.8
ENSMUST00000043429.12
ENSMUST00000145658.2
nuclear transcription factor-Y gamma
chr5_+_110987839 1.41 ENSMUST00000200172.2
ENSMUST00000066160.3
checkpoint kinase 2
chr19_-_11301919 1.39 ENSMUST00000159269.2
membrane-spanning 4-domains, subfamily A, member 7
chr9_-_48747232 1.36 ENSMUST00000093852.5
zinc finger and BTB domain containing 16
chr2_+_103800459 1.34 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr11_-_107238956 1.33 ENSMUST00000134763.2
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_-_17161504 1.27 ENSMUST00000020317.8
partner of NOB1 homolog
chr9_-_117081518 1.25 ENSMUST00000111773.10
ENSMUST00000068962.14
ENSMUST00000044901.14
RNA binding motif, single stranded interacting protein
chr13_-_3943433 1.24 ENSMUST00000222504.2
neuroepithelial cell transforming gene 1
chr13_+_36301331 1.23 ENSMUST00000021857.13
phenylalanine-tRNA synthetase 2 (mitochondrial)
chr2_+_103800553 1.22 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr1_-_134883577 1.18 ENSMUST00000168381.8
protein phosphatase 1, regulatory subunit 12B
chr10_+_94350687 1.18 ENSMUST00000065060.12
transmembrane and coiled coil domains 3
chr7_-_110681402 1.14 ENSMUST00000159305.2
eukaryotic translation initiation factor 4, gamma 2
chr5_+_110988095 1.13 ENSMUST00000198373.2
checkpoint kinase 2
chr17_+_35268942 1.13 ENSMUST00000007257.10
chloride intracellular channel 1
chr9_-_117979147 1.10 ENSMUST00000215799.2
ENSMUST00000044220.11
COX assembly mitochondrial protein 1
chr12_-_114487525 1.10 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr5_+_67125759 1.09 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr11_+_67167950 1.07 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr14_-_62718581 1.06 ENSMUST00000186010.8
predicted gene 4131
chr12_+_21366386 1.04 ENSMUST00000076813.8
ENSMUST00000221693.2
ENSMUST00000223345.2
ENSMUST00000222344.2
isoamyl acetate-hydrolyzing esterase 1 homolog
chr10_-_12689345 1.03 ENSMUST00000217899.2
utrophin
chr11_+_83742961 0.97 ENSMUST00000146786.8
HNF1 homeobox B
chrX_-_161612373 0.97 ENSMUST00000041370.11
ENSMUST00000112316.9
ENSMUST00000112315.2
taxilin gamma
chr7_+_122723365 0.97 ENSMUST00000205514.2
ENSMUST00000094053.7
trinucleotide repeat containing 6a
chr12_+_35975619 0.90 ENSMUST00000042101.5
ENSMUST00000154042.2
anterior gradient 3
chr18_-_84104574 0.90 ENSMUST00000175783.3
teashirt zinc finger family member 1
chr19_+_41471395 0.85 ENSMUST00000237208.2
ENSMUST00000238398.2
ligand dependent nuclear receptor corepressor
chr1_+_21419819 0.85 ENSMUST00000088407.4
KH domain containing 1A
chr6_-_114898739 0.84 ENSMUST00000032459.14
vestigial like family member 4
chr2_+_3115250 0.81 ENSMUST00000072955.12
family with sequence similarity 171, member A1
chr10_+_53472853 0.80 ENSMUST00000219271.2
anti-silencing function 1A histone chaperone
chr11_-_78074377 0.80 ENSMUST00000102483.5
ribosomal protein L23A
chr1_+_157334298 0.76 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr5_-_44956981 0.75 ENSMUST00000070748.10
LIM domain binding 2
chr11_-_40586029 0.75 ENSMUST00000101347.10
methionine adenosyltransferase II, beta
chr1_+_157334347 0.74 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr5_-_73789764 0.74 ENSMUST00000087177.4
leucine rich repeat containing 66
chr19_+_43770619 0.73 ENSMUST00000026208.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr5_-_44956932 0.72 ENSMUST00000199261.2
ENSMUST00000199534.5
LIM domain binding 2
chr4_-_130169006 0.72 ENSMUST00000122374.8
serine incorporator 2
chr18_-_84104507 0.71 ENSMUST00000060303.10
teashirt zinc finger family member 1
chr19_+_44551280 0.70 ENSMUST00000040455.5
hypoxia-inducible factor 1, alpha subunit inhibitor
chr9_-_117080869 0.70 ENSMUST00000172564.3
RNA binding motif, single stranded interacting protein
chr1_+_36550948 0.69 ENSMUST00000001166.14
ENSMUST00000097776.4
cyclin M3
chrX_-_50106844 0.68 ENSMUST00000053593.8
RAP2C, member of RAS oncogene family
chr7_+_101619897 0.65 ENSMUST00000211272.2
nuclear mitotic apparatus protein 1
chr11_-_43317017 0.65 ENSMUST00000101340.11
ENSMUST00000118368.8
ENSMUST00000020685.10
ENSMUST00000020687.15
pituitary tumor-transforming gene 1
chr19_-_56536443 0.65 ENSMUST00000182059.2
DNA cross-link repair 1A
chr5_-_110987604 0.64 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr4_-_60377932 0.63 ENSMUST00000107506.9
ENSMUST00000122381.8
ENSMUST00000118759.8
ENSMUST00000132829.3
major urinary protein 9
chr4_-_60222580 0.63 ENSMUST00000095058.5
ENSMUST00000163931.8
major urinary protein 8
chr13_-_19521337 0.63 ENSMUST00000103563.3
T cell receptor gamma variable 2
chr5_-_124492734 0.60 ENSMUST00000031341.11
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr13_-_46881388 0.59 ENSMUST00000021803.10
nucleoporin 153
chr2_+_103799873 0.59 ENSMUST00000123437.8
LIM domain only 2
chr4_+_62398262 0.58 ENSMUST00000030088.12
ENSMUST00000107449.4
B-box and SPRY domain containing
chr7_+_98089623 0.57 ENSMUST00000206435.2
guanylate cyclase 2d
chr2_+_85420854 0.57 ENSMUST00000052307.5
olfactory receptor 998
chr10_+_122284404 0.56 ENSMUST00000020323.7
arginine vasopressin receptor 1A
chr11_-_68864666 0.56 ENSMUST00000038644.5
RAN guanine nucleotide release factor
chr17_+_8591228 0.51 ENSMUST00000163578.8
brachyury 2
chr10_-_116417333 0.50 ENSMUST00000218744.2
ENSMUST00000105267.8
ENSMUST00000105265.8
ENSMUST00000167706.8
ENSMUST00000168036.8
ENSMUST00000169921.8
ENSMUST00000020374.6
CCR4-NOT transcription complex, subunit 2
chr5_-_44957016 0.50 ENSMUST00000199256.5
LIM domain binding 2
chrX_+_162694397 0.49 ENSMUST00000140845.2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_51366306 0.45 ENSMUST00000226210.2
ribonuclease, RNase A family, 6
chr18_-_43610829 0.45 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr13_-_103901010 0.43 ENSMUST00000210489.2
splicing regulatory glutamine/lysine-rich protein 1
chr10_-_53506038 0.42 ENSMUST00000218549.3
minichromosome maintenance 9 homologous recombination repair factor
chr9_-_48391838 0.42 ENSMUST00000216470.2
ENSMUST00000217037.2
ENSMUST00000034524.5
ENSMUST00000213895.2
RNA exonuclease 2
chr6_+_134897473 0.42 ENSMUST00000204807.2
cyclin-dependent kinase inhibitor 1B
chr13_+_83672965 0.40 ENSMUST00000199432.5
ENSMUST00000198069.5
ENSMUST00000197681.5
ENSMUST00000197722.5
ENSMUST00000197938.5
myocyte enhancer factor 2C
chr1_+_60948149 0.40 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr7_+_5037117 0.38 ENSMUST00000076791.4
RIKEN cDNA 4632433K11 gene
chr17_+_26471870 0.37 ENSMUST00000025023.15
Luc7-like
chr9_-_103242096 0.36 ENSMUST00000116517.9
carnitine deficiency-associated gene expressed in ventricle 3
chr5_+_88523967 0.35 ENSMUST00000073363.2
amelotin
chr13_-_21964747 0.34 ENSMUST00000080511.3
H1.5 linker histone, cluster member
chr4_+_32238950 0.33 ENSMUST00000037416.13
BTB and CNC homology, basic leucine zipper transcription factor 2
chrX_-_58612709 0.33 ENSMUST00000124402.2
fibroblast growth factor 13
chr16_-_43484494 0.33 ENSMUST00000096065.6
T cell immunoreceptor with Ig and ITIM domains
chr2_-_164231015 0.32 ENSMUST00000167427.2
secretory leukocyte peptidase inhibitor
chr6_+_134897364 0.31 ENSMUST00000067327.11
ENSMUST00000003115.9
cyclin-dependent kinase inhibitor 1B
chr4_+_109200225 0.31 ENSMUST00000030281.12
epidermal growth factor receptor pathway substrate 15
chr2_+_89760155 0.31 ENSMUST00000111516.2
olfactory receptor 1258
chr3_+_85946145 0.31 ENSMUST00000238331.2
SH3 domain protein D19
chr2_-_4656870 0.30 ENSMUST00000192470.2
ENSMUST00000035721.14
ENSMUST00000152362.7
pre-mRNA processing factor 18
chrX_-_105528503 0.30 ENSMUST00000138724.8
ENSMUST00000149331.2
fibronectin type III domain containing 3C1
chr2_-_103609703 0.28 ENSMUST00000143188.2
cell cycle associated protein 1
chr16_-_45975440 0.28 ENSMUST00000059524.7
predicted gene 4737
chr1_-_132958299 0.27 ENSMUST00000190807.2
transformed mouse 3T3 cell double minute 4
chr5_+_4073343 0.27 ENSMUST00000238634.2
A kinase (PRKA) anchor protein (yotiao) 9
chr8_+_84724130 0.26 ENSMUST00000095228.5
sterile alpha motif domain containing 1
chr4_-_101750986 0.26 ENSMUST00000051043.4
RIKEN cDNA C130073F10 gene
chr9_-_103079312 0.25 ENSMUST00000035157.10
signal recognition particle receptor, B subunit
chr4_+_147445744 0.21 ENSMUST00000133078.8
ENSMUST00000154154.2
zinc finger protein 978
chr1_-_86038394 0.21 ENSMUST00000155077.2
5-hydroxytryptamine (serotonin) receptor 2B
chr1_-_36982747 0.20 ENSMUST00000185964.3
transmembrane protein 131
chr7_-_106491314 0.20 ENSMUST00000088687.3
olfactory receptor 707
chr2_-_86528739 0.19 ENSMUST00000214141.2
olfactory receptor 1087
chr4_-_61259997 0.19 ENSMUST00000071005.9
ENSMUST00000075206.12
major urinary protein 14
chr12_+_87921198 0.18 ENSMUST00000110145.12
ENSMUST00000181843.2
ENSMUST00000180706.8
ENSMUST00000181394.8
ENSMUST00000181326.8
ENSMUST00000181300.2
predicted gene 2042
chr5_+_147366953 0.18 ENSMUST00000031651.15
PAN3 poly(A) specific ribonuclease subunit
chr13_+_119599287 0.18 ENSMUST00000026519.10
ENSMUST00000225186.2
ENSMUST00000224081.2
ENSMUST00000224312.2
RIKEN cDNA 4833420G17 gene
chr2_-_93988229 0.18 ENSMUST00000028619.5
hydroxysteroid (17-beta) dehydrogenase 12
chr19_+_8595369 0.17 ENSMUST00000010250.4
solute carrier family 22 (organic anion transporter), member 6
chr19_-_56536646 0.15 ENSMUST00000182276.2
DNA cross-link repair 1A
chr6_+_134807170 0.13 ENSMUST00000111937.2
cAMP responsive element binding protein-like 2
chr4_-_118792037 0.11 ENSMUST00000081960.5
olfactory receptor 1328
chr6_+_30401864 0.11 ENSMUST00000068240.13
ENSMUST00000068259.10
ENSMUST00000132581.8
kelch domain containing 10
chr4_-_118687635 0.10 ENSMUST00000076019.4
olfactory receptor 1333
chr7_-_104296512 0.10 ENSMUST00000210641.2
ENSMUST00000089296.3
olfactory receptor 658
chr1_+_173964312 0.09 ENSMUST00000053941.4
olfactory receptor 424
chr3_+_138233004 0.08 ENSMUST00000196990.5
ENSMUST00000200239.5
ENSMUST00000200100.2
eukaryotic translation initiation factor 4E
chr7_-_103393740 0.07 ENSMUST00000216300.2
olfactory receptor 629
chr5_-_87634665 0.07 ENSMUST00000201519.2
predicted gene 43638
chr2_-_34261121 0.06 ENSMUST00000127353.3
ENSMUST00000141653.3
pre B cell leukemia homeobox 3
chr10_-_130116088 0.06 ENSMUST00000061571.5
neurogenic differentiation 4
chr16_+_8288627 0.05 ENSMUST00000046470.16
ENSMUST00000150790.2
ENSMUST00000142899.2
methyltransferase like 22
chr6_+_83142902 0.04 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr5_-_21150470 0.03 ENSMUST00000197089.2
round spermatid basic protein 1-like
chr19_-_4384029 0.02 ENSMUST00000176653.2
lysine (K)-specific demethylase 2A
chr9_-_39465349 0.01 ENSMUST00000215505.2
ENSMUST00000217227.2
olfactory receptor 958
chr3_+_89366425 0.01 ENSMUST00000029564.12
phosphomevalonate kinase
chr9_+_88721217 0.01 ENSMUST00000163255.9
ENSMUST00000186363.2
tripartite motif-containing 43C
chr2_-_89502276 0.01 ENSMUST00000214639.2
ENSMUST00000214304.2
olfactory receptor 1251
chr12_-_32258469 0.00 ENSMUST00000085469.6
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr12_+_17316546 0.00 ENSMUST00000057288.7
ENSMUST00000239402.2
protein disulfide isomerase associated 6
chr4_-_132649798 0.00 ENSMUST00000097856.10
ENSMUST00000030696.11
family with sequence similarity 76, member A
chr3_-_100591906 0.00 ENSMUST00000130066.2
mannosidase, alpha, class 1A, member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
1.8 5.3 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
1.4 4.3 GO:0046967 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) cytosol to ER transport(GO:0046967)
1.1 4.6 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
1.0 2.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.9 5.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 2.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.7 2.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.6 3.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 2.5 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.6 5.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.6 2.3 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.5 4.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.5 2.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.4 1.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 7.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.0 GO:0006116 NADH oxidation(GO:0006116)
0.3 2.5 GO:0031179 peptide modification(GO:0031179)
0.3 6.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.3 1.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) tolerance induction dependent upon immune response(GO:0002461)
0.3 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.0 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.6 GO:0060023 soft palate development(GO:0060023)
0.2 2.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.6 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 3.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 0.7 GO:0016999 antibiotic metabolic process(GO:0016999)
0.2 2.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 9.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 0.7 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2 1.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.5 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 3.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.0 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.6 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 3.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 1.5 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:0014028 notochord formation(GO:0014028)
0.1 0.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 2.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 1.1 GO:0030049 muscle filament sliding(GO:0030049)
0.1 1.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.6 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 3.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 2.3 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 3.0 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.3 GO:0003283 atrial septum development(GO:0003283)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 1.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 10.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.1 5.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.9 2.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.7 2.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.5 4.3 GO:0042825 TAP complex(GO:0042825)
0.5 9.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 2.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 3.0 GO:0005579 membrane attack complex(GO:0005579)
0.3 5.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 4.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 2.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 3.9 GO:0032982 myosin filament(GO:0032982)
0.1 0.7 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 6.6 GO:0005604 basement membrane(GO:0005604)
0.0 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.0 GO:0070938 contractile ring(GO:0070938)
0.0 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 8.0 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 3.7 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.4 4.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.9 5.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.7 2.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.6 9.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 2.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.5 3.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 2.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 1.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 5.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 6.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.9 GO:0004875 complement receptor activity(GO:0004875)
0.2 1.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 4.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 2.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.6 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 7.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 8.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 3.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 3.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 9.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 5.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 3.0 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 2.9 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.2 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 5.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 10.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 5.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.3 PID SHP2 PATHWAY SHP2 signaling
0.1 2.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 8.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 6.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 4.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 4.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 9.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 9.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 4.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 2.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 4.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 6.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 5.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development