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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for GAGAUGA

Z-value: 0.60

Motif logo

logo of

miRNA associated with seed GAGAUGA

NamemiRBASE accession
mmu-miR-143-3p
MIMAT0000247

Activity profile of GAGAUGA motif

Sorted Z-values of GAGAUGA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGAUGA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_46571910 3.40 ENSMUST00000037923.5
Rbm24
RNA binding motif protein 24
chr1_-_72914036 2.80 ENSMUST00000027377.9
Igfbp5
insulin-like growth factor binding protein 5
chr10_+_17672004 2.60 ENSMUST00000037964.7
Txlnb
taxilin beta
chr4_+_141148068 2.56 ENSMUST00000102486.5
Hspb7
heat shock protein family, member 7 (cardiovascular)
chrX_-_102865546 2.20 ENSMUST00000042664.10
Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
chr11_-_88609048 2.10 ENSMUST00000107909.8
Msi2
musashi RNA-binding protein 2
chr8_-_116434517 2.03 ENSMUST00000109104.2
Maf
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr15_-_11905697 1.97 ENSMUST00000066529.5
ENSMUST00000228603.2
Npr3
natriuretic peptide receptor 3
chr9_-_20726344 1.84 ENSMUST00000004201.8
Col5a3
collagen, type V, alpha 3
chr6_-_38853097 1.81 ENSMUST00000161779.8
Hipk2
homeodomain interacting protein kinase 2
chr6_-_82751429 1.78 ENSMUST00000000642.11
Hk2
hexokinase 2
chr9_-_101128976 1.71 ENSMUST00000075941.12
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr19_+_56276343 1.49 ENSMUST00000095948.11
Habp2
hyaluronic acid binding protein 2
chr16_+_42727926 1.45 ENSMUST00000151244.8
ENSMUST00000114694.9
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_129030710 1.41 ENSMUST00000102600.4
Fndc5
fibronectin type III domain containing 5
chr15_+_58805605 1.36 ENSMUST00000022980.5
Ndufb9
NADH:ubiquinone oxidoreductase subunit B9
chr15_+_102875229 1.32 ENSMUST00000001699.8
Hoxc10
homeobox C10
chr7_-_115637970 1.22 ENSMUST00000166877.8
Sox6
SRY (sex determining region Y)-box 6
chr18_+_4921663 1.19 ENSMUST00000143254.8
Svil
supervillin
chr4_+_135933676 1.14 ENSMUST00000047526.8
Asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr2_+_78699360 1.14 ENSMUST00000028398.14
Ube2e3
ubiquitin-conjugating enzyme E2E 3
chr17_-_12988492 1.13 ENSMUST00000024599.14
Igf2r
insulin-like growth factor 2 receptor
chr18_+_38383297 1.10 ENSMUST00000025314.7
ENSMUST00000236078.2
Dele1
DAP3 binding cell death enhancer 1
chr16_+_35891991 1.07 ENSMUST00000164916.9
Ccdc58
coiled-coil domain containing 58
chr4_+_116953218 1.04 ENSMUST00000030443.12
Ptch2
patched 2
chr4_+_123095297 1.01 ENSMUST00000068262.6
Nt5c1a
5'-nucleotidase, cytosolic IA
chr7_+_128125339 1.00 ENSMUST00000033136.9
Bag3
BCL2-associated athanogene 3
chrX_+_105230706 0.98 ENSMUST00000081593.13
Pgk1
phosphoglycerate kinase 1
chr9_+_30941924 0.93 ENSMUST00000216649.2
ENSMUST00000115222.10
Zbtb44
zinc finger and BTB domain containing 44
chr11_+_60913386 0.89 ENSMUST00000089184.11
Kcnj12
potassium inwardly-rectifying channel, subfamily J, member 12
chr7_-_89166781 0.88 ENSMUST00000041761.7
Prss23
protease, serine 23
chr4_-_132149780 0.78 ENSMUST00000102568.10
Phactr4
phosphatase and actin regulator 4
chrX_-_139443926 0.78 ENSMUST00000055738.12
Tsc22d3
TSC22 domain family, member 3
chr19_+_4560500 0.75 ENSMUST00000068004.13
ENSMUST00000224726.3
Pcx
pyruvate carboxylase
chr19_-_47452840 0.74 ENSMUST00000081619.10
Sh3pxd2a
SH3 and PX domains 2A
chr11_-_115188337 0.73 ENSMUST00000056153.8
Fads6
fatty acid desaturase domain family, member 6
chr14_+_7030760 0.72 ENSMUST00000055211.6
Lrrc3b
leucine rich repeat containing 3B
chr19_-_17333972 0.72 ENSMUST00000174236.8
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
chr6_-_101354858 0.71 ENSMUST00000075994.11
Pdzrn3
PDZ domain containing RING finger 3
chr6_+_113460258 0.64 ENSMUST00000032422.6
Creld1
cysteine-rich with EGF-like domains 1
chr2_-_167032068 0.62 ENSMUST00000059826.10
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr4_-_120604445 0.62 ENSMUST00000030376.8
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr6_+_120813199 0.62 ENSMUST00000009256.4
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr8_-_125675901 0.61 ENSMUST00000034469.7
Egln1
egl-9 family hypoxia-inducible factor 1
chr12_-_85386120 0.61 ENSMUST00000040992.8
Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chr11_-_47270201 0.60 ENSMUST00000077221.6
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr3_-_27764571 0.58 ENSMUST00000046157.10
Fndc3b
fibronectin type III domain containing 3B
chr7_-_98010534 0.57 ENSMUST00000165257.8
Tsku
tsukushi, small leucine rich proteoglycan
chr7_+_45063079 0.56 ENSMUST00000058879.8
Ntf5
neurotrophin 5
chr6_-_59001455 0.53 ENSMUST00000089860.12
Fam13a
family with sequence similarity 13, member A
chr15_-_96597610 0.53 ENSMUST00000023099.8
Slc38a2
solute carrier family 38, member 2
chr12_+_86725459 0.52 ENSMUST00000021681.4
Vash1
vasohibin 1
chr15_-_50753061 0.52 ENSMUST00000165201.9
ENSMUST00000184458.8
Trps1
transcriptional repressor GATA binding 1
chr2_-_155771938 0.51 ENSMUST00000152766.8
ENSMUST00000139232.8
ENSMUST00000109632.8
ENSMUST00000006036.13
ENSMUST00000142655.2
ENSMUST00000159238.2
Uqcc1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr12_+_3857001 0.51 ENSMUST00000020991.15
ENSMUST00000172509.8
Dnmt3a
DNA methyltransferase 3A
chr2_+_173579285 0.50 ENSMUST00000067530.6
Vapb
vesicle-associated membrane protein, associated protein B and C
chr19_+_10872778 0.50 ENSMUST00000179297.3
Prpf19
pre-mRNA processing factor 19
chr2_-_74489763 0.49 ENSMUST00000173623.2
ENSMUST00000001867.13
Evx2
even-skipped homeobox 2
chr1_+_187730018 0.48 ENSMUST00000027906.13
Esrrg
estrogen-related receptor gamma
chr9_+_62585108 0.48 ENSMUST00000034774.9
Itga11
integrin alpha 11
chr14_+_65596070 0.45 ENSMUST00000066994.7
Zfp395
zinc finger protein 395
chr10_-_43050516 0.45 ENSMUST00000040275.9
Sobp
sine oculis binding protein
chr11_+_105183463 0.42 ENSMUST00000100335.10
ENSMUST00000021038.5
Mrc2
mannose receptor, C type 2
chr4_-_58206596 0.42 ENSMUST00000042850.9
Svep1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr10_+_121200984 0.42 ENSMUST00000040344.7
Gns
glucosamine (N-acetyl)-6-sulfatase
chr8_+_80366247 0.42 ENSMUST00000173078.8
ENSMUST00000173286.8
Otud4
OTU domain containing 4
chr2_-_63928339 0.41 ENSMUST00000131615.9
Fign
fidgetin
chrX_-_141749704 0.40 ENSMUST00000041317.3
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_-_87878301 0.40 ENSMUST00000020775.9
Dynll2
dynein light chain LC8-type 2
chr1_-_45542442 0.39 ENSMUST00000086430.5
Col5a2
collagen, type V, alpha 2
chr7_+_67602565 0.39 ENSMUST00000005671.10
Igf1r
insulin-like growth factor I receptor
chr6_+_100681670 0.39 ENSMUST00000032157.9
Gxylt2
glucoside xylosyltransferase 2
chr15_-_102630589 0.38 ENSMUST00000023818.11
Calcoco1
calcium binding and coiled coil domain 1
chr12_+_52746158 0.38 ENSMUST00000095737.5
Akap6
A kinase (PRKA) anchor protein 6
chr16_+_35803674 0.36 ENSMUST00000004054.13
Kpna1
karyopherin (importin) alpha 1
chr12_-_46865709 0.35 ENSMUST00000021438.8
Nova1
NOVA alternative splicing regulator 1
chr2_-_160950936 0.34 ENSMUST00000039782.14
ENSMUST00000134178.8
Chd6
chromodomain helicase DNA binding protein 6
chr4_+_62883796 0.34 ENSMUST00000030043.13
ENSMUST00000107415.8
ENSMUST00000064814.6
Zfp618
zinc finger protein 618
chr12_-_119202527 0.33 ENSMUST00000026360.9
Itgb8
integrin beta 8
chr4_+_31964082 0.33 ENSMUST00000037607.11
ENSMUST00000080933.13
ENSMUST00000108183.8
ENSMUST00000108184.3
Map3k7
mitogen-activated protein kinase kinase kinase 7
chr19_-_42601202 0.33 ENSMUST00000166128.2
ENSMUST00000026190.14
ENSMUST00000164786.8
Loxl4
lysyl oxidase-like 4
chr11_+_30721726 0.32 ENSMUST00000041231.14
Psme4
proteasome (prosome, macropain) activator subunit 4
chr1_-_184543367 0.32 ENSMUST00000048462.13
ENSMUST00000110992.9
Mtarc1
mitochondrial amidoxime reducing component 1
chr1_-_105284383 0.31 ENSMUST00000058688.7
Rnf152
ring finger protein 152
chr1_-_21149392 0.31 ENSMUST00000037998.6
Tram2
translocating chain-associating membrane protein 2
chr5_+_43390513 0.30 ENSMUST00000166713.9
ENSMUST00000169035.8
ENSMUST00000114065.9
Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr11_-_29464998 0.28 ENSMUST00000133103.2
ENSMUST00000039900.4
Prorsd1
prolyl-tRNA synthetase domain containing 1
chr7_+_27878894 0.28 ENSMUST00000085901.13
ENSMUST00000172761.8
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr8_+_40964818 0.28 ENSMUST00000098817.4
Vps37a
vacuolar protein sorting 37A
chr7_-_109585649 0.27 ENSMUST00000094097.12
Tmem41b
transmembrane protein 41B
chr5_+_32293145 0.26 ENSMUST00000031017.11
Fosl2
fos-like antigen 2
chr8_+_31601837 0.25 ENSMUST00000046941.8
ENSMUST00000217278.2
Rnf122
ring finger protein 122
chr9_-_107167046 0.25 ENSMUST00000035194.8
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr1_-_157240138 0.25 ENSMUST00000078308.13
Rasal2
RAS protein activator like 2
chr12_+_91367764 0.25 ENSMUST00000021346.14
ENSMUST00000021343.8
Tshr
thyroid stimulating hormone receptor
chr17_-_74257164 0.24 ENSMUST00000024866.6
Xdh
xanthine dehydrogenase
chr12_-_21336285 0.23 ENSMUST00000076260.12
Itgb1bp1
integrin beta 1 binding protein 1
chr13_+_24985640 0.23 ENSMUST00000019276.12
BC005537
cDNA sequence BC005537
chr17_-_42922286 0.22 ENSMUST00000068355.8
Opn5
opsin 5
chr11_+_57899890 0.22 ENSMUST00000071487.13
ENSMUST00000178636.2
Larp1
La ribonucleoprotein domain family, member 1
chr6_+_134012602 0.21 ENSMUST00000081028.13
ENSMUST00000111963.8
Etv6
ets variant 6
chr1_+_87254719 0.21 ENSMUST00000027475.15
Gigyf2
GRB10 interacting GYF protein 2
chr4_+_132001680 0.21 ENSMUST00000030731.11
ENSMUST00000105963.2
Taf12
TATA-box binding protein associated factor 12
chr7_-_134539993 0.21 ENSMUST00000171394.3
Insyn2a
inhibitory synaptic factor 2A
chr8_+_105897300 0.20 ENSMUST00000052209.9
ENSMUST00000109392.9
ENSMUST00000109395.8
Cbfb
core binding factor beta
chr4_+_20008357 0.20 ENSMUST00000117632.8
ENSMUST00000098244.2
Ttpa
tocopherol (alpha) transfer protein
chr7_+_16043502 0.19 ENSMUST00000002152.13
Bbc3
BCL2 binding component 3
chr12_-_51738666 0.19 ENSMUST00000013130.15
ENSMUST00000169503.4
Strn3
striatin, calmodulin binding protein 3
chr15_-_73056713 0.19 ENSMUST00000044113.12
Ago2
argonaute RISC catalytic subunit 2
chr3_+_30847024 0.18 ENSMUST00000029256.9
Sec62
SEC62 homolog (S. cerevisiae)
chr2_-_150327011 0.16 ENSMUST00000109914.2
Zfp345
zinc finger protein 345
chrX_-_138772383 0.16 ENSMUST00000033811.14
ENSMUST00000087401.12
Morc4
microrchidia 4
chr9_+_45749869 0.16 ENSMUST00000078111.11
ENSMUST00000034591.11
Bace1
beta-site APP cleaving enzyme 1
chr6_-_88022172 0.15 ENSMUST00000203674.3
ENSMUST00000204126.2
ENSMUST00000113596.8
ENSMUST00000113600.10
Rab7
RAB7, member RAS oncogene family
chr19_-_12773472 0.15 ENSMUST00000038627.9
Zfp91
zinc finger protein 91
chr7_-_121620366 0.15 ENSMUST00000033160.15
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr11_+_117545618 0.15 ENSMUST00000106344.8
Tnrc6c
trinucleotide repeat containing 6C
chrX_-_103244784 0.14 ENSMUST00000118314.8
Nexmif
neurite extension and migration factor
chr2_+_71617266 0.14 ENSMUST00000112101.8
ENSMUST00000028522.10
Itga6
integrin alpha 6
chr5_-_143717970 0.14 ENSMUST00000053287.6
Usp42
ubiquitin specific peptidase 42
chr5_+_103902020 0.13 ENSMUST00000054979.10
Aff1
AF4/FMR2 family, member 1
chr13_-_93636224 0.13 ENSMUST00000220513.2
ENSMUST00000065537.9
Jmy
junction-mediating and regulatory protein
chr19_-_5168251 0.13 ENSMUST00000113728.8
ENSMUST00000113727.8
ENSMUST00000025798.13
Klc2
kinesin light chain 2
chrX_+_47430221 0.13 ENSMUST00000136348.8
Bcorl1
BCL6 co-repressor-like 1
chr8_-_106553822 0.13 ENSMUST00000239468.2
ENSMUST00000041400.6
Ranbp10
RAN binding protein 10
chr7_+_79992839 0.12 ENSMUST00000032747.7
ENSMUST00000206480.2
ENSMUST00000206074.2
ENSMUST00000206122.2
Hddc3
HD domain containing 3
chr10_-_59277570 0.11 ENSMUST00000009798.5
Oit3
oncoprotein induced transcript 3
chr15_-_97729341 0.11 ENSMUST00000079838.14
ENSMUST00000118294.8
Hdac7
histone deacetylase 7
chr11_+_105480796 0.10 ENSMUST00000168598.8
ENSMUST00000100330.10
Tanc2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_+_8209216 0.10 ENSMUST00000040017.8
Mios
meiosis regulator for oocyte development
chr5_+_69714279 0.10 ENSMUST00000087228.11
ENSMUST00000031113.13
ENSMUST00000173205.3
Guf1
GUF1 homolog, GTPase
chr2_-_84508385 0.10 ENSMUST00000189772.2
ENSMUST00000053664.9
ENSMUST00000111664.8
Gm28635
Tmx2
predicted gene 28635
thioredoxin-related transmembrane protein 2
chr1_+_138891447 0.09 ENSMUST00000168527.8
Dennd1b
DENN/MADD domain containing 1B
chr14_-_73622638 0.09 ENSMUST00000228637.2
ENSMUST00000022704.9
Itm2b
integral membrane protein 2B
chr2_-_132089543 0.09 ENSMUST00000110164.8
Tmem230
transmembrane protein 230
chr2_-_163261439 0.08 ENSMUST00000046908.10
Oser1
oxidative stress responsive serine rich 1
chrX_+_36137948 0.07 ENSMUST00000016452.11
ENSMUST00000202991.4
ENSMUST00000201068.4
ENSMUST00000200835.4
Ube2a
ubiquitin-conjugating enzyme E2A
chr12_-_83968507 0.07 ENSMUST00000222439.2
ENSMUST00000135962.8
ENSMUST00000155112.8
ENSMUST00000136848.8
ENSMUST00000126943.2
ENSMUST00000117217.8
Numb
NUMB endocytic adaptor protein
chr7_+_18659787 0.07 ENSMUST00000032571.10
ENSMUST00000220302.2
Nova2
NOVA alternative splicing regulator 2
chr18_+_36812246 0.06 ENSMUST00000186538.7
Slc35a4
solute carrier family 35, member A4
chrX_+_9066105 0.05 ENSMUST00000069763.3
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr15_-_103163860 0.04 ENSMUST00000075192.13
Nfe2
nuclear factor, erythroid derived 2
chr2_+_180351910 0.04 ENSMUST00000029090.9
Gid8
GID complex subunit 8
chr6_-_71417607 0.04 ENSMUST00000002292.15
Rmnd5a
required for meiotic nuclear division 5 homolog A
chr11_-_102907991 0.04 ENSMUST00000021313.9
Dcakd
dephospho-CoA kinase domain containing
chr11_+_115272732 0.03 ENSMUST00000053288.6
Cdr2l
cerebellar degeneration-related protein 2-like
chr4_-_126861918 0.02 ENSMUST00000106108.9
Zmym4
zinc finger, MYM-type 4
chr18_-_77652820 0.01 ENSMUST00000026494.14
ENSMUST00000182024.2
Rnf165
ring finger protein 165
chr15_-_93173032 0.01 ENSMUST00000057896.5
ENSMUST00000049484.13
ENSMUST00000230063.2
Gxylt1
glucoside xylosyltransferase 1
chr3_+_95532282 0.01 ENSMUST00000058230.13
ENSMUST00000037983.6
Ensa
endosulfine alpha
chr15_-_103148239 0.00 ENSMUST00000118152.8
Cbx5
chromobox 5
chr17_+_46513666 0.00 ENSMUST00000087031.7
Xpo5
exportin 5
chr1_+_36550948 0.00 ENSMUST00000001166.14
ENSMUST00000097776.4
Cnnm3
cyclin M3
chr5_+_103573367 0.00 ENSMUST00000048957.11
Ptpn13
protein tyrosine phosphatase, non-receptor type 13

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.4 1.8 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.3 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 2.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 0.8 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.6 GO:0061193 taste bud development(GO:0061193)
0.2 0.5 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.2 0.6 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.5 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.1 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 1.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.0 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 1.4 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 1.0 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.5 GO:0032328 alanine transport(GO:0032328)
0.0 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 2.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.4 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:1904587 response to glycoprotein(GO:1904587)
0.0 3.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.6 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 2.6 GO:0009408 response to heat(GO:0009408)
0.0 0.5 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.5 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.1 1.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 2.6 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 2.7 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974) DNA replication factor A complex(GO:0005662)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.3 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 2.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 2.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.8 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 0.7 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.0 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.8 GO:0046790 virion binding(GO:0046790)
0.1 0.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 2.6 GO:0031005 filamin binding(GO:0031005)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 2.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449) sulfate binding(GO:0043199)
0.1 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.2 GO:0043546 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 1.8 GO:0043394 proteoglycan binding(GO:0043394)
0.0 3.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.6 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis