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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for GGAAGAC

Z-value: 0.71

Motif logo

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miRNA associated with seed GGAAGAC

NamemiRBASE accession
mmu-miR-7a-5p
MIMAT0000677
mmu-miR-7b-5p
MIMAT0000678

Activity profile of GGAAGAC motif

Sorted Z-values of GGAAGAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAGAC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_42073737 7.05 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_-_42301574 6.47 ENSMUST00000031891.15
ENSMUST00000143278.8
Fam131b
family with sequence similarity 131, member B
chr2_-_155356716 5.93 ENSMUST00000029131.11
Ggt7
gamma-glutamyltransferase 7
chr4_-_15149051 5.83 ENSMUST00000041606.14
Necab1
N-terminal EF-hand calcium binding protein 1
chr6_-_60806810 5.79 ENSMUST00000163779.8
Snca
synuclein, alpha
chr10_-_80861239 5.64 ENSMUST00000055125.5
Diras1
DIRAS family, GTP-binding RAS-like 1
chr7_+_3381434 5.39 ENSMUST00000092891.6
Cacng7
calcium channel, voltage-dependent, gamma subunit 7
chr7_+_43959637 5.37 ENSMUST00000107938.8
Shank1
SH3 and multiple ankyrin repeat domains 1
chr9_-_21963306 5.11 ENSMUST00000003501.9
ENSMUST00000215901.2
Elavl3
ELAV like RNA binding protein 3
chr6_+_86055048 4.99 ENSMUST00000032069.8
Add2
adducin 2 (beta)
chrX_-_69408627 4.58 ENSMUST00000101509.9
Ids
iduronate 2-sulfatase
chr3_-_57755500 4.57 ENSMUST00000066882.10
Pfn2
profilin 2
chr13_-_105191403 4.53 ENSMUST00000063551.7
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr19_+_5348329 4.48 ENSMUST00000061169.7
Gal3st3
galactose-3-O-sulfotransferase 3
chr17_+_27874519 4.26 ENSMUST00000045896.11
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr11_-_75686874 4.19 ENSMUST00000021209.8
Doc2b
double C2, beta
chr7_-_64806164 4.04 ENSMUST00000148459.3
ENSMUST00000119118.8
Fam189a1
family with sequence similarity 189, member A1
chr13_+_117738972 3.75 ENSMUST00000006991.9
Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
chr9_+_45029080 3.38 ENSMUST00000170998.9
ENSMUST00000093855.4
Scn2b
sodium channel, voltage-gated, type II, beta
chr3_+_108498595 3.23 ENSMUST00000051145.15
Wdr47
WD repeat domain 47
chr1_+_153528689 3.21 ENSMUST00000041776.12
Rgs8
regulator of G-protein signaling 8
chr12_-_81827893 3.04 ENSMUST00000035987.9
Map3k9
mitogen-activated protein kinase kinase kinase 9
chr7_-_43139390 2.89 ENSMUST00000107974.3
Iglon5
IgLON family member 5
chr1_-_173195236 2.84 ENSMUST00000005470.5
ENSMUST00000111220.8
Cadm3
cell adhesion molecule 3
chr13_+_110039620 2.83 ENSMUST00000120664.8
Pde4d
phosphodiesterase 4D, cAMP specific
chr15_+_41652777 2.76 ENSMUST00000230778.2
ENSMUST00000022918.15
ENSMUST00000090095.13
Oxr1
oxidation resistance 1
chr4_-_119349760 2.60 ENSMUST00000049994.8
Rimkla
ribosomal modification protein rimK-like family member A
chr12_+_95658987 2.49 ENSMUST00000057324.4
Flrt2
fibronectin leucine rich transmembrane protein 2
chr11_+_110956980 2.30 ENSMUST00000042970.3
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr16_+_6166982 2.27 ENSMUST00000056416.9
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_84498196 2.27 ENSMUST00000137170.3
Lin52
lin-52 homolog (C. elegans)
chr18_+_36926929 2.24 ENSMUST00000001419.10
Zmat2
zinc finger, matrin type 2
chr6_+_85408953 2.21 ENSMUST00000045693.8
Smyd5
SET and MYND domain containing 5
chr18_+_59308722 2.18 ENSMUST00000080721.6
Chsy3
chondroitin sulfate synthase 3
chr4_+_48045143 2.17 ENSMUST00000030025.10
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_-_118800314 2.15 ENSMUST00000117731.8
ENSMUST00000106278.9
ENSMUST00000120061.8
ENSMUST00000017576.11
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr6_-_136150076 2.07 ENSMUST00000053880.13
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr17_-_52139693 2.05 ENSMUST00000144331.8
Satb1
special AT-rich sequence binding protein 1
chr6_-_119307685 2.03 ENSMUST00000112756.8
ENSMUST00000068351.14
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr15_-_78602971 2.00 ENSMUST00000088592.6
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr5_+_146321757 1.96 ENSMUST00000016143.9
Wasf3
WASP family, member 3
chr2_+_105499233 1.91 ENSMUST00000111086.11
ENSMUST00000111087.10
Pax6
paired box 6
chr7_+_109617456 1.87 ENSMUST00000084731.5
Ipo7
importin 7
chr8_-_47805383 1.86 ENSMUST00000110367.10
Stox2
storkhead box 2
chr8_-_17585263 1.79 ENSMUST00000082104.7
Csmd1
CUB and Sushi multiple domains 1
chr2_-_92264374 1.67 ENSMUST00000111278.2
ENSMUST00000090559.12
Cry2
cryptochrome 2 (photolyase-like)
chr9_+_113641615 1.67 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
Clasp2
CLIP associating protein 2
chr11_+_102652228 1.67 ENSMUST00000103081.10
ENSMUST00000068150.7
Adam11
a disintegrin and metallopeptidase domain 11
chr14_-_65335479 1.58 ENSMUST00000225633.2
ENSMUST00000022550.8
Extl3
exostosin-like glycosyltransferase 3
chr11_+_100465730 1.58 ENSMUST00000103120.5
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr13_+_45660905 1.57 ENSMUST00000000260.13
Gmpr
guanosine monophosphate reductase
chr13_+_42862957 1.53 ENSMUST00000066928.12
ENSMUST00000148891.8
Phactr1
phosphatase and actin regulator 1
chr7_+_100355798 1.50 ENSMUST00000107042.9
ENSMUST00000207564.2
ENSMUST00000049053.9
Fam168a
family with sequence similarity 168, member A
chr3_+_138231935 1.49 ENSMUST00000029803.12
Eif4e
eukaryotic translation initiation factor 4E
chr1_-_16727067 1.49 ENSMUST00000188641.7
Eloc
elongin C
chr2_-_34716083 1.47 ENSMUST00000113077.8
ENSMUST00000028220.10
Fbxw2
F-box and WD-40 domain protein 2
chr15_+_99599978 1.45 ENSMUST00000023759.6
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr7_+_121888520 1.41 ENSMUST00000064989.12
ENSMUST00000064921.5
Prkcb
protein kinase C, beta
chr6_+_96090127 1.39 ENSMUST00000122120.8
Tafa1
TAFA chemokine like family member 1
chr10_+_85857726 1.31 ENSMUST00000130320.8
Fbxo7
F-box protein 7
chr4_-_135221926 1.31 ENSMUST00000102549.10
Nipal3
NIPA-like domain containing 3
chr5_-_31453206 1.28 ENSMUST00000041266.11
ENSMUST00000172435.8
ENSMUST00000201417.2
Fndc4
fibronectin type III domain containing 4
chr17_+_70276068 1.27 ENSMUST00000133983.8
Dlgap1
DLG associated protein 1
chr2_-_167032068 1.26 ENSMUST00000059826.10
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr1_-_143652711 1.26 ENSMUST00000159879.2
Ro60
Ro60, Y RNA binding protein
chr4_-_149783097 1.23 ENSMUST00000038859.14
ENSMUST00000105690.9
Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr15_-_48655329 1.20 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
Csmd3
CUB and Sushi multiple domains 3
chr15_-_98661076 1.20 ENSMUST00000053183.12
Arf3
ADP-ribosylation factor 3
chr16_+_32427738 1.16 ENSMUST00000023486.15
Tfrc
transferrin receptor
chr11_-_79037213 1.10 ENSMUST00000018478.11
ENSMUST00000108264.8
Ksr1
kinase suppressor of ras 1
chr3_+_123240562 1.09 ENSMUST00000029603.10
Prss12
protease, serine 12 neurotrypsin (motopsin)
chr13_+_75237939 1.08 ENSMUST00000022075.6
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr1_+_180396478 1.06 ENSMUST00000027777.12
Parp1
poly (ADP-ribose) polymerase family, member 1
chr8_+_13919641 1.00 ENSMUST00000051870.8
ENSMUST00000128557.3
Champ1
chromosome alignment maintaining phosphoprotein 1
chr11_-_102588536 0.98 ENSMUST00000164506.3
ENSMUST00000092569.13
Ccdc43
coiled-coil domain containing 43
chr11_+_52251687 0.97 ENSMUST00000102758.8
Vdac1
voltage-dependent anion channel 1
chr1_+_60448703 0.97 ENSMUST00000052332.15
Abi2
abl interactor 2
chr2_-_130480014 0.96 ENSMUST00000089561.10
ENSMUST00000110260.8
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr10_-_120815232 0.94 ENSMUST00000119944.8
ENSMUST00000119093.2
Lemd3
LEM domain containing 3
chr1_-_34882131 0.93 ENSMUST00000167518.8
ENSMUST00000047534.12
Fam168b
family with sequence similarity 168, member B
chr7_+_29991101 0.93 ENSMUST00000150892.2
ENSMUST00000126216.2
ENSMUST00000014065.16
Clip3
CAP-GLY domain containing linker protein 3
chr7_+_18659787 0.92 ENSMUST00000032571.10
ENSMUST00000220302.2
Nova2
NOVA alternative splicing regulator 2
chr2_+_91560472 0.89 ENSMUST00000099712.10
ENSMUST00000111317.9
ENSMUST00000111316.9
ENSMUST00000045705.14
Ambra1
autophagy/beclin 1 regulator 1
chr8_-_71916244 0.87 ENSMUST00000008094.10
Abhd8
abhydrolase domain containing 8
chr10_-_62322551 0.84 ENSMUST00000105447.11
Vps26a
VPS26 retromer complex component A
chr4_+_49632046 0.82 ENSMUST00000156314.8
ENSMUST00000167496.8
ENSMUST00000029989.11
ENSMUST00000146547.2
Rnf20
ring finger protein 20
chr4_-_70453140 0.77 ENSMUST00000107359.9
Megf9
multiple EGF-like-domains 9
chr11_+_52122836 0.75 ENSMUST00000037324.12
ENSMUST00000166537.8
Skp1
S-phase kinase-associated protein 1
chr2_+_181162278 0.68 ENSMUST00000072334.12
Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
chr11_+_97253221 0.68 ENSMUST00000238729.2
ENSMUST00000045540.4
Socs7
suppressor of cytokine signaling 7
chr6_+_86826470 0.67 ENSMUST00000089519.13
ENSMUST00000204414.3
Aak1
AP2 associated kinase 1
chr7_-_126807581 0.60 ENSMUST00000120705.3
Tbc1d10b
TBC1 domain family, member 10b
chr17_-_66384017 0.59 ENSMUST00000150766.2
ENSMUST00000038116.13
Ankrd12
ankyrin repeat domain 12
chr16_+_3702523 0.57 ENSMUST00000176625.8
ENSMUST00000186375.8
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr11_+_102175757 0.57 ENSMUST00000036376.13
ENSMUST00000100387.11
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr1_-_151965876 0.54 ENSMUST00000044581.14
1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr11_-_44361289 0.54 ENSMUST00000102795.4
Ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr11_+_101207021 0.53 ENSMUST00000142640.8
ENSMUST00000019470.14
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr9_-_95393909 0.53 ENSMUST00000190019.2
ENSMUST00000185515.7
ENSMUST00000217176.2
ENSMUST00000079659.12
ENSMUST00000078374.13
U2surp
U2 snRNP-associated SURP domain containing
chr19_+_55304703 0.52 ENSMUST00000225529.2
ENSMUST00000223690.2
ENSMUST00000095950.3
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chr11_-_6425877 0.51 ENSMUST00000179343.3
Purb
purine rich element binding protein B
chr18_-_33596792 0.50 ENSMUST00000051087.16
Nrep
neuronal regeneration related protein
chr8_-_111985824 0.48 ENSMUST00000169020.8
ENSMUST00000003404.9
Glg1
golgi apparatus protein 1
chr9_+_109760528 0.48 ENSMUST00000035055.15
Map4
microtubule-associated protein 4
chr3_+_34074048 0.48 ENSMUST00000001620.13
Fxr1
fragile X mental retardation gene 1, autosomal homolog
chr12_+_85520652 0.47 ENSMUST00000021674.7
Fos
FBJ osteosarcoma oncogene
chr12_-_26465253 0.45 ENSMUST00000020971.14
Rnf144a
ring finger protein 144A
chr18_+_69478790 0.45 ENSMUST00000202116.4
ENSMUST00000114982.8
ENSMUST00000078486.13
ENSMUST00000202772.4
ENSMUST00000201288.4
Tcf4
transcription factor 4
chr9_-_96634874 0.42 ENSMUST00000152594.8
Zbtb38
zinc finger and BTB domain containing 38
chr16_+_33005426 0.42 ENSMUST00000232100.2
ENSMUST00000232181.2
ENSMUST00000039733.10
Osbpl11
oxysterol binding protein-like 11
chrX_+_100683662 0.41 ENSMUST00000119299.8
ENSMUST00000044475.5
Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr5_-_92231314 0.41 ENSMUST00000169094.8
ENSMUST00000167918.8
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr19_-_12773472 0.41 ENSMUST00000038627.9
Zfp91
zinc finger protein 91
chr11_-_61745843 0.41 ENSMUST00000004920.4
Ulk2
unc-51 like kinase 2
chr6_-_82629835 0.38 ENSMUST00000160281.8
ENSMUST00000095786.6
Pole4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr11_+_72580823 0.35 ENSMUST00000155998.2
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr11_-_78642480 0.34 ENSMUST00000059468.6
Ccnq
cyclin Q
chr9_+_57496725 0.33 ENSMUST00000053230.7
Ulk3
unc-51-like kinase 3
chr4_-_120144546 0.33 ENSMUST00000102656.4
Foxo6
forkhead box O6
chr3_+_68776884 0.32 ENSMUST00000054551.3
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr12_+_4819277 0.32 ENSMUST00000020967.11
Pfn4
profilin family, member 4
chr19_-_53378990 0.32 ENSMUST00000025997.7
Smndc1
survival motor neuron domain containing 1
chr3_+_88461059 0.31 ENSMUST00000008748.8
Ubqln4
ubiquilin 4
chr1_+_127701901 0.30 ENSMUST00000112570.2
ENSMUST00000027587.15
Ccnt2
cyclin T2
chr16_-_87229485 0.30 ENSMUST00000039449.9
Ltn1
listerin E3 ubiquitin protein ligase 1
chr10_-_59787646 0.29 ENSMUST00000020308.5
Ddit4
DNA-damage-inducible transcript 4
chr14_-_71004019 0.28 ENSMUST00000167242.8
Xpo7
exportin 7
chr15_-_96597610 0.28 ENSMUST00000023099.8
Slc38a2
solute carrier family 38, member 2
chr3_+_146110387 0.27 ENSMUST00000106151.8
ENSMUST00000106153.9
ENSMUST00000039021.11
ENSMUST00000106149.8
ENSMUST00000149262.8
Ssx2ip
synovial sarcoma, X 2 interacting protein
chr1_-_58625431 0.26 ENSMUST00000161000.2
ENSMUST00000161600.8
Fam126b
family with sequence similarity 126, member B
chr7_-_110443557 0.25 ENSMUST00000177462.8
ENSMUST00000176716.3
ENSMUST00000176746.8
ENSMUST00000177236.8
Rnf141
ring finger protein 141
chr10_+_74896383 0.21 ENSMUST00000164107.3
Bcr
BCR activator of RhoGEF and GTPase
chr7_-_63588610 0.21 ENSMUST00000063694.10
Klf13
Kruppel-like factor 13
chr15_+_93296225 0.20 ENSMUST00000109256.11
ENSMUST00000049122.16
ENSMUST00000068457.15
Pphln1
periphilin 1
chr14_-_40735710 0.20 ENSMUST00000143143.8
ENSMUST00000128236.2
ENSMUST00000022317.15
ENSMUST00000118466.8
Prxl2a
peroxiredoxin like 2A
chr1_+_75119419 0.18 ENSMUST00000097694.11
ENSMUST00000190240.7
Retreg2
reticulophagy regulator family member 2
chr2_+_32340459 0.18 ENSMUST00000048431.3
Naif1
nuclear apoptosis inducing factor 1
chr10_+_76367427 0.16 ENSMUST00000048678.7
Lss
lanosterol synthase
chr1_+_176642226 0.15 ENSMUST00000056773.15
ENSMUST00000027785.15
Sdccag8
serologically defined colon cancer antigen 8
chr11_+_98754434 0.14 ENSMUST00000142414.8
ENSMUST00000037480.9
Wipf2
WAS/WASL interacting protein family, member 2
chr2_+_131028861 0.12 ENSMUST00000028804.15
ENSMUST00000079857.9
Cdc25b
cell division cycle 25B
chr2_-_167334746 0.11 ENSMUST00000109211.9
ENSMUST00000057627.16
Spata2
spermatogenesis associated 2
chr9_-_44179758 0.11 ENSMUST00000034621.16
ENSMUST00000168499.9
Nlrx1
NLR family member X1
chr10_+_62756409 0.11 ENSMUST00000044977.10
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr10_-_119075910 0.10 ENSMUST00000020315.13
Cand1
cullin associated and neddylation disassociated 1
chr16_+_20470402 0.10 ENSMUST00000007212.9
ENSMUST00000232629.2
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr1_-_182169150 0.10 ENSMUST00000051431.10
Fbxo28
F-box protein 28
chr18_-_38345010 0.10 ENSMUST00000159405.3
ENSMUST00000160721.8
Pcdh1
protocadherin 1
chr16_-_13977084 0.08 ENSMUST00000090300.6
Marf1
meiosis regulator and mRNA stability 1
chr8_+_95328558 0.07 ENSMUST00000060389.10
ENSMUST00000212729.2
ENSMUST00000121101.2
Rspry1
ring finger and SPRY domain containing 1
chr9_+_57615816 0.06 ENSMUST00000043990.14
ENSMUST00000142807.2
Edc3
enhancer of mRNA decapping 3
chr14_-_8457069 0.05 ENSMUST00000022257.4
Atxn7
ataxin 7
chr6_+_8209216 0.05 ENSMUST00000040017.8
Mios
meiosis regulator for oocyte development
chr4_+_137321451 0.04 ENSMUST00000105840.8
ENSMUST00000105839.8
ENSMUST00000055131.13
ENSMUST00000105838.8
Usp48
ubiquitin specific peptidase 48
chr5_-_36905983 0.01 ENSMUST00000071949.5
Bloc1s4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr6_-_115652831 0.01 ENSMUST00000112949.8
Raf1
v-raf-leukemia viral oncogene 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.2 3.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.8 2.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.7 3.4 GO:0046684 response to pyrethroid(GO:0046684)
0.6 1.7 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.5 2.2 GO:1900623 positive regulation of mast cell cytokine production(GO:0032765) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 5.4 GO:0046959 habituation(GO:0046959)
0.5 1.9 GO:0003322 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.4 5.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 2.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 1.5 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.4 1.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 7.0 GO:0071420 cellular response to histamine(GO:0071420)
0.3 4.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 3.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 4.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 2.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 1.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 1.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 2.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.8 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 5.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 1.3 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 4.2 GO:0097320 membrane tubulation(GO:0097320)
0.1 5.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.9 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 1.3 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 2.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.2 GO:0033572 transferrin transport(GO:0033572)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 2.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.6 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 3.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 4.5 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 1.8 GO:0001964 startle response(GO:0001964)
0.0 0.9 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 2.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 2.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 2.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 1.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 1.5 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.2 3.7 GO:0098855 HCN channel complex(GO:0098855)
0.6 1.7 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.5 1.6 GO:1902560 GMP reductase complex(GO:1902560)
0.3 1.3 GO:1990037 Lewy body core(GO:1990037)
0.3 7.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 4.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 7.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.5 GO:0070449 elongin complex(GO:0070449)
0.2 2.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 1.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 0.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 4.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 5.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 4.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 4.7 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 2.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.9 7.0 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.8 5.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.7 2.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 2.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.6 3.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 1.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.5 5.8 GO:1903136 cuprous ion binding(GO:1903136)
0.5 1.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.5 2.6 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.5 3.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 1.5 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.5 5.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 3.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 4.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 1.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.9 GO:0097001 ceramide binding(GO:0097001)
0.2 2.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.7 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 5.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 4.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0015288 porin activity(GO:0015288)
0.1 5.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.4 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 2.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 3.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 5.0 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 4.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 3.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 7.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 5.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 2.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 5.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 3.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 7.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling