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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for GGAGUGU

Z-value: 0.55

Motif logo

logo of

miRNA associated with seed GGAGUGU

NamemiRBASE accession
mmu-miR-122-5p
MIMAT0000246

Activity profile of GGAGUGU motif

Sorted Z-values of GGAGUGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAGUGU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_44499451 3.58 ENSMUST00000024755.7
Clic5
chloride intracellular channel 5
chr7_+_16515265 2.40 ENSMUST00000108496.9
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chrX_+_74425990 1.95 ENSMUST00000033541.5
Fundc2
FUN14 domain containing 2
chr7_-_126398343 1.95 ENSMUST00000032934.12
Aldoa
aldolase A, fructose-bisphosphate
chr7_+_45084257 1.83 ENSMUST00000003964.17
Gys1
glycogen synthase 1, muscle
chr11_-_40646090 1.69 ENSMUST00000020576.8
Ccng1
cyclin G1
chr1_-_164285914 1.42 ENSMUST00000027863.13
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr13_-_97235745 1.42 ENSMUST00000071118.7
Gm6169
predicted gene 6169
chr14_-_121742659 1.42 ENSMUST00000088386.8
Slc15a1
solute carrier family 15 (oligopeptide transporter), member 1
chr14_-_106134253 1.27 ENSMUST00000022709.6
Spry2
sprouty RTK signaling antagonist 2
chr19_-_40576782 1.05 ENSMUST00000176939.8
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr2_-_173118315 1.02 ENSMUST00000036248.13
Pmepa1
prostate transmembrane protein, androgen induced 1
chr4_+_136013372 0.89 ENSMUST00000069195.5
ENSMUST00000130658.2
Zfp46
zinc finger protein 46
chr7_-_16657825 0.85 ENSMUST00000019514.10
Calm3
calmodulin 3
chr1_-_22031718 0.84 ENSMUST00000029667.13
ENSMUST00000173058.8
ENSMUST00000173404.2
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr6_-_85046430 0.82 ENSMUST00000160197.6
Exoc6b
exocyst complex component 6B
chr16_-_31019967 0.82 ENSMUST00000230614.2
ENSMUST00000058033.9
Acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr3_+_156267429 0.81 ENSMUST00000074015.11
Negr1
neuronal growth regulator 1
chr5_-_148336711 0.81 ENSMUST00000048116.15
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_-_141351110 0.80 ENSMUST00000038661.8
Slc25a34
solute carrier family 25, member 34
chr15_+_76235503 0.80 ENSMUST00000023212.15
ENSMUST00000160172.8
Maf1
MAF1 homolog, negative regulator of RNA polymerase III
chr10_+_59159118 0.80 ENSMUST00000009789.15
ENSMUST00000092512.11
ENSMUST00000105466.3
P4ha1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr15_+_37233280 0.79 ENSMUST00000161405.8
ENSMUST00000022895.15
ENSMUST00000161532.2
Grhl2
grainyhead like transcription factor 2
chr10_+_128173603 0.78 ENSMUST00000005826.9
Cs
citrate synthase
chr7_-_80453033 0.77 ENSMUST00000167377.3
Iqgap1
IQ motif containing GTPase activating protein 1
chr17_-_17845293 0.73 ENSMUST00000041047.4
Lnpep
leucyl/cystinyl aminopeptidase
chr1_+_75522902 0.71 ENSMUST00000124341.8
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr3_+_108191398 0.68 ENSMUST00000135636.6
ENSMUST00000102632.7
Sort1
sortilin 1
chrX_+_95139639 0.68 ENSMUST00000117399.2
Msn
moesin
chr9_+_96078340 0.66 ENSMUST00000034982.16
ENSMUST00000188008.7
ENSMUST00000188750.7
ENSMUST00000185644.7
Tfdp2
transcription factor Dp 2
chr16_+_10884156 0.65 ENSMUST00000089011.6
Snn
stannin
chr1_+_131755715 0.64 ENSMUST00000086559.7
Slc41a1
solute carrier family 41, member 1
chr9_+_54493784 0.64 ENSMUST00000167866.2
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr5_-_69749617 0.64 ENSMUST00000173927.8
ENSMUST00000120789.8
ENSMUST00000031117.13
Gnpda2
glucosamine-6-phosphate deaminase 2
chr1_-_174749379 0.64 ENSMUST00000055294.4
Grem2
gremlin 2, DAN family BMP antagonist
chr9_-_50571080 0.60 ENSMUST00000034567.4
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr19_+_10366753 0.59 ENSMUST00000169121.9
ENSMUST00000076968.11
ENSMUST00000235479.2
ENSMUST00000223586.2
ENSMUST00000235784.2
ENSMUST00000224135.3
ENSMUST00000225452.3
ENSMUST00000237366.2
Syt7
synaptotagmin VII
chr19_+_11493825 0.59 ENSMUST00000163078.8
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr11_-_98980122 0.58 ENSMUST00000017751.3
Tns4
tensin 4
chr11_+_77384234 0.57 ENSMUST00000037285.10
ENSMUST00000100812.4
Git1
GIT ArfGAP 1
chr7_-_16796309 0.56 ENSMUST00000153833.2
ENSMUST00000108492.9
Hif3a
hypoxia inducible factor 3, alpha subunit
chr12_-_55867941 0.55 ENSMUST00000085385.7
ENSMUST00000110687.8
Ralgapa1
Ral GTPase activating protein, alpha subunit 1
chr8_-_74080101 0.54 ENSMUST00000119826.7
ENSMUST00000212459.2
Large1
LARGE xylosyl- and glucuronyltransferase 1
chr8_+_40760499 0.54 ENSMUST00000068999.14
Micu3
mitochondrial calcium uptake family, member 3
chrX_+_100892981 0.54 ENSMUST00000124279.6
ENSMUST00000101339.8
Nhsl2
NHS-like 2
chr1_-_135302971 0.54 ENSMUST00000041240.4
Shisa4
shisa family member 4
chr8_+_12807001 0.54 ENSMUST00000033818.10
ENSMUST00000091237.12
Atp11a
ATPase, class VI, type 11A
chr19_-_6947112 0.50 ENSMUST00000025912.10
Plcb3
phospholipase C, beta 3
chr19_-_47525437 0.50 ENSMUST00000182808.8
ENSMUST00000182714.2
ENSMUST00000049369.16
Stn1
STN1, CST complex subunit
chr2_+_112097087 0.49 ENSMUST00000110987.9
ENSMUST00000028549.14
Slc12a6
solute carrier family 12, member 6
chr1_-_74990821 0.48 ENSMUST00000164097.4
Ihh
Indian hedgehog
chr11_-_87249837 0.47 ENSMUST00000055438.5
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr12_-_98225676 0.46 ENSMUST00000021390.9
Galc
galactosylceramidase
chr11_+_102080446 0.45 ENSMUST00000070334.10
G6pc3
glucose 6 phosphatase, catalytic, 3
chr8_+_89373943 0.45 ENSMUST00000118370.8
ENSMUST00000054324.15
Nod2
nucleotide-binding oligomerization domain containing 2
chr4_-_151142351 0.42 ENSMUST00000030797.4
Vamp3
vesicle-associated membrane protein 3
chr10_+_94350687 0.41 ENSMUST00000065060.12
Tmcc3
transmembrane and coiled coil domains 3
chr5_+_143450329 0.40 ENSMUST00000045593.12
Daglb
diacylglycerol lipase, beta
chr1_+_155034452 0.40 ENSMUST00000027743.13
ENSMUST00000195302.6
Stx6
syntaxin 6
chr2_-_120234539 0.38 ENSMUST00000090042.12
ENSMUST00000110729.2
ENSMUST00000090046.12
Tmem87a
transmembrane protein 87A
chr2_-_25498459 0.37 ENSMUST00000058137.9
Rabl6
RAB, member RAS oncogene family-like 6
chr10_+_69932930 0.36 ENSMUST00000147545.8
Ccdc6
coiled-coil domain containing 6
chr4_-_133399909 0.34 ENSMUST00000062118.11
ENSMUST00000067902.13
Pigv
phosphatidylinositol glycan anchor biosynthesis, class V
chr8_+_4216556 0.34 ENSMUST00000239400.2
ENSMUST00000177053.8
ENSMUST00000176149.9
ENSMUST00000176072.9
ENSMUST00000176825.3
Evi5l
ecotropic viral integration site 5 like
chr11_+_69871952 0.31 ENSMUST00000108593.8
Ctdnep1
CTD nuclear envelope phosphatase 1
chr15_+_76423012 0.31 ENSMUST00000023220.10
Slc52a2
solute carrier protein 52, member 2
chrX_+_165021897 0.30 ENSMUST00000112235.8
Gpm6b
glycoprotein m6b
chr3_+_88049633 0.29 ENSMUST00000001455.13
ENSMUST00000119251.8
Mef2d
myocyte enhancer factor 2D
chr16_+_10306075 0.27 ENSMUST00000023147.8
Ciita
class II transactivator
chr11_+_50492899 0.27 ENSMUST00000142118.3
ENSMUST00000040523.9
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr4_+_123095297 0.26 ENSMUST00000068262.6
Nt5c1a
5'-nucleotidase, cytosolic IA
chr4_+_133097013 0.26 ENSMUST00000030669.8
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr1_+_59952131 0.26 ENSMUST00000036540.12
Fam117b
family with sequence similarity 117, member B
chrX_+_41591355 0.25 ENSMUST00000189753.7
Sh2d1a
SH2 domain containing 1A
chr10_-_42152684 0.23 ENSMUST00000175881.8
ENSMUST00000056974.4
ENSMUST00000105502.8
ENSMUST00000105501.2
Foxo3
forkhead box O3
chr6_-_92683136 0.23 ENSMUST00000032093.12
Prickle2
prickle planar cell polarity protein 2
chr14_-_121616616 0.21 ENSMUST00000079817.8
Stk24
serine/threonine kinase 24
chr13_+_21901791 0.21 ENSMUST00000188775.2
H3c10
H3 clustered histone 10
chr15_-_51855073 0.20 ENSMUST00000022927.11
Rad21
RAD21 cohesin complex component
chr14_+_54701594 0.19 ENSMUST00000022782.10
Lrp10
low-density lipoprotein receptor-related protein 10
chr4_-_129636073 0.18 ENSMUST00000066257.6
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr7_-_25418401 0.18 ENSMUST00000125699.3
ENSMUST00000002683.3
Ccdc97
coiled-coil domain containing 97
chr8_-_80784619 0.18 ENSMUST00000079038.4
Hhip
Hedgehog-interacting protein
chrX_+_98864627 0.17 ENSMUST00000096363.3
Tmem28
transmembrane protein 28
chr4_-_45408646 0.17 ENSMUST00000153904.2
ENSMUST00000132815.3
ENSMUST00000107796.8
ENSMUST00000116341.4
Slc25a51
solute carrier family 25, member 51
chrX_+_100342749 0.17 ENSMUST00000118111.8
ENSMUST00000130555.8
ENSMUST00000151528.8
Nlgn3
neuroligin 3
chr19_+_11446716 0.16 ENSMUST00000165310.3
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr4_+_99952988 0.16 ENSMUST00000039630.6
Ror1
receptor tyrosine kinase-like orphan receptor 1
chr16_+_32734464 0.16 ENSMUST00000023491.13
ENSMUST00000170899.8
ENSMUST00000170201.8
ENSMUST00000165616.8
ENSMUST00000135193.9
Lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_-_135000109 0.16 ENSMUST00000037099.9
Clic4
chloride intracellular channel 4 (mitochondrial)
chr4_-_41569500 0.15 ENSMUST00000108049.9
ENSMUST00000108052.10
ENSMUST00000108050.2
Fam219a
family with sequence similarity 219, member A
chrX_-_55643429 0.14 ENSMUST00000059899.3
Mmgt1
membrane magnesium transporter 1
chr3_+_108093645 0.14 ENSMUST00000050909.7
ENSMUST00000106659.3
ENSMUST00000106656.2
Amigo1
adhesion molecule with Ig like domain 1
chr15_-_13173736 0.13 ENSMUST00000036439.6
Cdh6
cadherin 6
chr7_-_81104423 0.12 ENSMUST00000178892.3
ENSMUST00000098331.10
Cpeb1
cytoplasmic polyadenylation element binding protein 1
chr11_-_97171294 0.09 ENSMUST00000167806.8
ENSMUST00000172108.8
ENSMUST00000001480.14
Npepps
aminopeptidase puromycin sensitive
chr11_-_61821072 0.09 ENSMUST00000102650.10
Akap10
A kinase (PRKA) anchor protein 10
chr2_-_153371861 0.09 ENSMUST00000035346.14
Nol4l
nucleolar protein 4-like
chr1_+_55276336 0.09 ENSMUST00000061334.10
Mars2
methionine-tRNA synthetase 2 (mitochondrial)
chr15_+_78912642 0.09 ENSMUST00000180086.3
H1f0
H1.0 linker histone
chr8_-_85549452 0.09 ENSMUST00000065539.6
Dand5
DAN domain family member 5, BMP antagonist
chr17_-_57242413 0.08 ENSMUST00000025053.10
Mllt1
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
chrX_-_100312629 0.08 ENSMUST00000117736.2
Gm20489
predicted gene 20489
chr18_+_77032080 0.08 ENSMUST00000026485.15
ENSMUST00000150990.9
ENSMUST00000148955.3
Hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
chr11_-_83320281 0.08 ENSMUST00000052521.9
Gas2l2
growth arrest-specific 2 like 2
chr7_+_43112569 0.07 ENSMUST00000107977.4
Vsig10l
V-set and immunoglobulin domain containing 10 like
chr7_-_126807581 0.07 ENSMUST00000120705.3
Tbc1d10b
TBC1 domain family, member 10b
chr1_-_13062873 0.06 ENSMUST00000188454.7
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr8_+_111821262 0.04 ENSMUST00000135302.8
ENSMUST00000039333.10
Pdpr
pyruvate dehydrogenase phosphatase regulatory subunit
chr12_-_111344139 0.02 ENSMUST00000041965.5
Cdc42bpb
CDC42 binding protein kinase beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0015825 L-serine transport(GO:0015825)
0.6 1.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 1.0 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.3 0.8 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.6 GO:0060300 regulation of cytokine activity(GO:0060300)
0.2 1.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.2 1.4 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 3.6 GO:0002024 diet induced thermogenesis(GO:0002024)
0.2 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.5 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 0.5 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) detection of peptidoglycan(GO:0032499) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) macrophage inflammatory protein-1 alpha production(GO:0071608) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.7 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.5 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.8 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 1.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:2000331 regulation of terminal button organization(GO:2000331)
0.0 0.8 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.8 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.0 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 2.0 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.5 GO:1990879 CST complex(GO:1990879)
0.2 0.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0032009 early phagosome(GO:0032009)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.8 GO:0030118 clathrin coat(GO:0030118)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.8 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.5 1.4 GO:0042936 dipeptide transporter activity(GO:0042936)
0.3 1.0 GO:0004350 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.2 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.9 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 0.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 1.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 2.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.8 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.1 GO:0016015 morphogen activity(GO:0016015)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 0.5 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 3.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 4.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 4.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis