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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Gata2_Gata1

Z-value: 2.45

Motif logo

Transcription factors associated with Gata2_Gata1

Gene Symbol Gene ID Gene Info
ENSMUSG00000015053.15 Gata2
ENSMUSG00000031162.15 Gata1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata1mm39_v1_chrX_-_7834057_78341490.458.3e-05Click!
Gata2mm39_v1_chr6_+_88175312_88175316-0.132.8e-01Click!

Activity profile of Gata2_Gata1 motif

Sorted Z-values of Gata2_Gata1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata2_Gata1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_41279199 32.48 ENSMUST00000031913.5
trypsin 4
chr17_-_26417982 31.27 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
protein disulfide isomerase associated 2
chr17_-_28779678 28.26 ENSMUST00000114785.3
ENSMUST00000025062.5
colipase, pancreatic
chr5_+_115604321 25.68 ENSMUST00000145785.8
ENSMUST00000031495.11
ENSMUST00000112071.8
ENSMUST00000125568.2
phospholipase A2, group IB, pancreas
chr7_-_4525426 22.99 ENSMUST00000209148.2
ENSMUST00000098859.10
troponin I, cardiac 3
chr6_+_30639217 21.65 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr9_-_99599312 20.72 ENSMUST00000112882.9
ENSMUST00000131922.2
claudin 18
chr17_-_31363245 19.95 ENSMUST00000024826.8
trefoil factor 2 (spasmolytic protein 1)
chr17_+_37180437 19.71 ENSMUST00000060524.11
tripartite motif-containing 10
chr7_-_4525793 19.53 ENSMUST00000140424.8
troponin I, cardiac 3
chr19_+_58658779 19.34 ENSMUST00000057270.9
pancreatic lipase
chr8_+_85428059 17.74 ENSMUST00000238364.2
ENSMUST00000238562.2
ENSMUST00000037165.6
lymphoblastomic leukemia 1
chr15_-_103159892 17.70 ENSMUST00000133600.8
ENSMUST00000134554.2
ENSMUST00000156927.8
nuclear factor, erythroid derived 2
chr1_-_138103021 16.84 ENSMUST00000182755.8
ENSMUST00000193650.2
ENSMUST00000182283.8
protein tyrosine phosphatase, receptor type, C
chr1_+_131671751 16.75 ENSMUST00000049027.10
solute carrier family 26, member 9
chr18_+_11052458 16.54 ENSMUST00000047762.10
GATA binding protein 6
chr1_-_138102972 16.31 ENSMUST00000195533.6
ENSMUST00000183301.8
protein tyrosine phosphatase, receptor type, C
chr2_+_84810802 16.19 ENSMUST00000028467.6
proteoglycan 2, bone marrow
chr19_-_10655391 15.77 ENSMUST00000025647.7
pepsinogen 5, group I
chr9_+_22011488 15.68 ENSMUST00000213607.2
calponin 1
chrX_+_139808351 15.63 ENSMUST00000033806.5
V-set and immunoglobulin domain containing 1
chrX_+_149330371 15.25 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr19_+_58658838 14.92 ENSMUST00000238108.2
pancreatic lipase
chr15_-_103160082 14.43 ENSMUST00000149111.8
ENSMUST00000132836.8
nuclear factor, erythroid derived 2
chr4_-_137157824 14.42 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr2_-_120867529 13.80 ENSMUST00000102490.10
erythrocyte membrane protein band 4.2
chr3_-_107129038 13.49 ENSMUST00000029504.9
chymosin
chr3_+_122688721 13.37 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chr4_-_46404224 13.33 ENSMUST00000107764.9
hemogen
chr11_+_95227836 13.23 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr6_-_41681273 13.01 ENSMUST00000031899.14
Kell blood group
chr2_-_120867232 12.70 ENSMUST00000023987.6
erythrocyte membrane protein band 4.2
chr9_+_46139878 12.53 ENSMUST00000034588.9
ENSMUST00000132155.2
apolipoprotein A-I
chr6_+_41331039 12.53 ENSMUST00000072103.7
trypsin 10
chr4_+_40920047 12.39 ENSMUST00000030122.5
serine peptidase inhibitor, Kazal type 4
chr9_-_32452885 11.99 ENSMUST00000016231.14
Friend leukemia integration 1
chr10_+_79855454 11.94 ENSMUST00000043311.7
Rho GTPase activating protein 45
chr19_-_6996791 11.33 ENSMUST00000040772.9
fermitin family member 3
chr11_+_70396070 11.32 ENSMUST00000019063.3
transmembrane 4 superfamily member 5
chr16_+_44913974 10.89 ENSMUST00000099498.10
coiled-coil domain containing 80
chr2_-_75534985 10.87 ENSMUST00000102672.5
nuclear factor, erythroid derived 2, like 2
chr9_-_44253588 10.78 ENSMUST00000215091.2
hydroxymethylbilane synthase
chr10_+_53213763 10.66 ENSMUST00000219491.2
ENSMUST00000163319.9
ENSMUST00000220197.2
ENSMUST00000046221.8
ENSMUST00000218468.2
ENSMUST00000219921.2
phospholamban
chr3_-_20296337 10.45 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr17_-_35304582 10.13 ENSMUST00000038507.7
lymphocyte antigen 6 complex, locus G6F
chr4_+_134591847 9.78 ENSMUST00000030627.8
Rh blood group, D antigen
chr9_-_44253630 9.68 ENSMUST00000097558.5
hydroxymethylbilane synthase
chr6_-_41291634 9.61 ENSMUST00000064324.12
trypsin 5
chr16_+_44914397 9.31 ENSMUST00000061050.6
coiled-coil domain containing 80
chr19_-_11058452 9.25 ENSMUST00000025636.8
membrane-spanning 4-domains, subfamily A, member 8A
chr19_-_6996696 8.93 ENSMUST00000236188.2
fermitin family member 3
chr7_-_80053063 8.88 ENSMUST00000147150.2
furin (paired basic amino acid cleaving enzyme)
chr16_+_38182569 8.79 ENSMUST00000023494.13
ENSMUST00000114739.2
popeye domain containing 2
chr9_+_20940669 8.75 ENSMUST00000001040.7
ENSMUST00000215077.2
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr14_-_63509131 8.68 ENSMUST00000132122.2
GATA binding protein 4
chr6_-_87327885 8.67 ENSMUST00000032129.3
gastrokine 1
chr6_+_41498716 8.66 ENSMUST00000070380.5
protease, serine 2
chr19_-_6065181 8.31 ENSMUST00000236537.2
ENSMUST00000025891.11
calpain 1
chr11_-_102360664 8.23 ENSMUST00000103086.4
integrin alpha 2b
chr2_-_153083322 8.18 ENSMUST00000056924.14
pleiomorphic adenoma gene-like 2
chr11_-_83177548 8.08 ENSMUST00000163961.3
schlafen 14
chr17_-_25394445 7.99 ENSMUST00000224277.2
proline and glutamate rich with coiled coil 1
chr15_+_55171138 7.83 ENSMUST00000023053.12
ENSMUST00000110217.10
collagen, type XIV, alpha 1
chr6_+_41435846 7.81 ENSMUST00000031910.8
protease, serine 1 (trypsin 1)
chr2_+_164245114 7.69 ENSMUST00000017151.2
recombination signal binding protein for immunoglobulin kappa J region-like
chr7_+_28240262 7.63 ENSMUST00000119180.4
syncollin
chr19_+_11724913 7.57 ENSMUST00000025585.4
cobalamin binding intrinsic factor
chr19_-_6065415 7.37 ENSMUST00000237519.2
calpain 1
chr6_+_67993691 7.27 ENSMUST00000103314.3
immunoglobulin kappa chain variable 1-122
chr8_-_110765983 7.23 ENSMUST00000109222.4
carbohydrate sulfotransferase 4
chr11_-_115968373 7.20 ENSMUST00000174822.8
unc-13 homolog D
chr8_+_13087292 7.10 ENSMUST00000063820.12
ENSMUST00000033821.11
coagulation factor X
chr8_+_13087805 7.00 ENSMUST00000128418.8
ENSMUST00000152034.2
coagulation factor X
chr11_-_115968745 6.76 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr3_+_89043440 6.60 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr3_+_93184854 6.56 ENSMUST00000180308.3
filaggrin
chr16_+_29884153 6.51 ENSMUST00000023171.8
hes family bHLH transcription factor 1
chr4_-_63779562 6.45 ENSMUST00000030047.3
tumor necrosis factor (ligand) superfamily, member 8
chr15_-_101848689 6.30 ENSMUST00000023799.8
keratin 79
chr6_+_30541581 6.29 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr6_-_136899167 6.26 ENSMUST00000032343.7
endoplasmic reticulum protein 27
chr16_+_58490625 6.12 ENSMUST00000060077.7
coproporphyrinogen oxidase
chr8_+_85428391 6.12 ENSMUST00000238338.2
lymphoblastomic leukemia 1
chr3_+_89043879 6.07 ENSMUST00000107482.10
ENSMUST00000127058.2
pyruvate kinase liver and red blood cell
chr10_+_87694117 6.00 ENSMUST00000122386.8
insulin-like growth factor 1
chr17_-_84495364 5.99 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr13_+_31809774 5.91 ENSMUST00000042054.3
forkhead box F2
chr2_+_84867554 5.85 ENSMUST00000077798.13
structure specific recognition protein 1
chr15_-_101262452 5.83 ENSMUST00000230909.2
keratin 80
chr4_+_11579648 5.70 ENSMUST00000180239.2
fibrinogen silencer binding protein
chr15_+_80507671 5.59 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr15_-_76501525 5.56 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr11_-_115968576 5.38 ENSMUST00000106450.8
unc-13 homolog D
chr14_+_26722319 5.32 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr8_-_86091970 5.29 ENSMUST00000121972.8
myosin light chain kinase 3
chr6_+_41369290 5.24 ENSMUST00000049079.9
predicted gene 5771
chr6_+_24597724 5.08 ENSMUST00000031694.8
leiomodin 2 (cardiac)
chr8_-_86091946 5.01 ENSMUST00000034133.14
myosin light chain kinase 3
chr19_-_6065799 4.98 ENSMUST00000235138.2
calpain 1
chr10_+_5543769 4.95 ENSMUST00000051809.10
myc target 1
chr2_+_72306503 4.92 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chr3_-_14873406 4.87 ENSMUST00000181860.8
ENSMUST00000144327.3
carbonic anhydrase 1
chr6_-_136918495 4.82 ENSMUST00000111892.8
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_23338960 4.75 ENSMUST00000211460.2
ENSMUST00000210658.2
ENSMUST00000209198.2
ENSMUST00000210371.2
ENSMUST00000211499.2
ENSMUST00000210795.2
ENSMUST00000209422.2
predicted gene 45338
receptor transporter protein 4
chr11_-_115967873 4.72 ENSMUST00000153408.8
unc-13 homolog D
chr2_+_103788321 4.67 ENSMUST00000156813.8
ENSMUST00000170926.8
LIM domain only 2
chr1_+_40468720 4.63 ENSMUST00000174335.8
interleukin 1 receptor-like 1
chr2_+_84867783 4.55 ENSMUST00000168266.8
ENSMUST00000130729.3
structure specific recognition protein 1
chr4_-_137137088 4.53 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr6_-_136918885 4.48 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chrX_-_59449137 4.46 ENSMUST00000033480.13
ENSMUST00000101527.3
ATPase, class VI, type 11C
chr2_+_3705824 4.45 ENSMUST00000115054.9
family with sequence similarity 107, member B
chr13_-_116446166 4.41 ENSMUST00000036060.13
ISL1 transcription factor, LIM/homeodomain
chr11_-_5848771 4.40 ENSMUST00000102921.4
myosin, light polypeptide 7, regulatory
chr14_+_14475188 4.37 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr1_+_45350698 4.21 ENSMUST00000087883.13
collagen, type III, alpha 1
chr4_+_133280680 4.15 ENSMUST00000042706.3
nuclear receptor subfamily 0, group B, member 2
chr3_+_108272205 4.08 ENSMUST00000090563.7
myosin binding protein H-like
chr7_-_119058489 4.08 ENSMUST00000207887.3
ENSMUST00000239424.2
ENSMUST00000033255.8
glycoprotein 2 (zymogen granule membrane)
chr3_+_79791798 4.04 ENSMUST00000118853.8
ENSMUST00000145992.2
golgi associated kinase 1B
chr5_-_73349191 3.95 ENSMUST00000176910.3
FRY like transcription coactivator
chr6_-_136918844 3.84 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_90948481 3.80 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chrX_-_7830405 3.77 ENSMUST00000128449.2
GATA binding protein 1
chr3_-_30067537 3.72 ENSMUST00000108270.10
MDS1 and EVI1 complex locus
chr5_-_83502793 3.65 ENSMUST00000146669.2
trans-2,3-enoyl-CoA reductase-like
chr8_-_110766009 3.60 ENSMUST00000212934.2
carbohydrate sulfotransferase 4
chr6_-_136918671 3.60 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr8_+_85635189 3.58 ENSMUST00000003910.13
ENSMUST00000109744.8
deoxyribonuclease II alpha
chr6_+_67701864 3.57 ENSMUST00000103304.3
immunoglobulin kappa variable 1-133
chr8_+_85635341 3.52 ENSMUST00000134569.2
deoxyribonuclease II alpha
chr6_+_115398996 3.49 ENSMUST00000000450.5
peroxisome proliferator activated receptor gamma
chr4_-_119047202 3.47 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
erythroblast membrane-associated protein
chr5_+_64969679 3.46 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr17_-_35285146 3.44 ENSMUST00000174190.2
ENSMUST00000097337.8
megakaryocyte and platelet inhibitory receptor G6b
chr5_+_32616187 3.44 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr8_-_86107593 3.43 ENSMUST00000122452.8
myosin light chain kinase 3
chr8_+_85635311 3.42 ENSMUST00000145292.8
deoxyribonuclease II alpha
chr7_-_141241632 3.40 ENSMUST00000239500.1
mucin 6, gastric
chr6_-_142647944 3.40 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_106980033 3.38 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr18_+_76192529 3.31 ENSMUST00000167921.2
zinc finger and BTB domain containing 7C
chr11_-_99328969 3.30 ENSMUST00000017743.3
keratin 20
chr2_+_69500444 3.30 ENSMUST00000100050.4
kelch-like 41
chr8_+_121215155 3.29 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr3_-_30067285 3.25 ENSMUST00000172694.8
MDS1 and EVI1 complex locus
chr7_-_4400704 3.07 ENSMUST00000108590.4
ENSMUST00000206928.2
glycoprotein 6 (platelet)
chr16_-_95260104 3.07 ENSMUST00000176345.10
ENSMUST00000121809.11
ENSMUST00000233664.2
ENSMUST00000122199.10
ETS transcription factor
chr5_-_83502966 3.06 ENSMUST00000053543.11
trans-2,3-enoyl-CoA reductase-like
chr3_-_75177378 2.97 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_-_125357756 2.97 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr4_-_119047167 2.91 ENSMUST00000030396.15
erythroblast membrane-associated protein
chr6_+_125529911 2.91 ENSMUST00000112254.8
ENSMUST00000112253.6
Von Willebrand factor
chr1_-_136888118 2.86 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr4_-_59438633 2.79 ENSMUST00000040166.14
ENSMUST00000107544.2
sushi domain containing 1
chr8_-_84771610 2.77 ENSMUST00000061923.5
relaxin 3
chr14_-_70945434 2.72 ENSMUST00000228346.2
exportin 7
chr1_+_180770064 2.71 ENSMUST00000159436.8
transmembrane protein 63a
chr10_-_80269436 2.68 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr1_-_45965661 2.67 ENSMUST00000186804.2
ENSMUST00000187406.7
ENSMUST00000187420.7
solute carrier family 40 (iron-regulated transporter), member 1
chr5_-_73787646 2.60 ENSMUST00000152215.3
leucine rich repeat containing 66
chr11_-_86248395 2.56 ENSMUST00000043624.9
mediator complex subunit 13
chr5_+_31454939 2.56 ENSMUST00000201675.3
glucokinase regulatory protein
chr6_+_15185202 2.55 ENSMUST00000154448.2
forkhead box P2
chr7_-_98887770 2.44 ENSMUST00000064231.8
monoacylglycerol O-acyltransferase 2
chr6_+_15185399 2.41 ENSMUST00000115474.8
ENSMUST00000115472.8
ENSMUST00000031545.14
forkhead box P2
chr6_+_17306379 2.39 ENSMUST00000115455.3
caveolin 1, caveolae protein
chr18_-_78166595 2.39 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr4_-_87724533 2.37 ENSMUST00000126353.8
ENSMUST00000149357.8
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr6_+_17306414 2.34 ENSMUST00000150901.2
caveolin 1, caveolae protein
chr10_-_80257681 2.31 ENSMUST00000156244.2
transcription factor 3
chr9_-_57743989 2.30 ENSMUST00000164010.8
ENSMUST00000171444.8
ENSMUST00000098686.4
AT rich interactive domain 3B (BRIGHT-like)
chr16_+_25620652 2.29 ENSMUST00000115304.8
ENSMUST00000115305.2
ENSMUST00000040231.13
ENSMUST00000115306.8
transformation related protein 63
chr15_+_76788270 2.29 ENSMUST00000004072.10
ENSMUST00000229183.2
ribosomal protein L8
chr4_-_14621669 2.28 ENSMUST00000143105.2
solute carrier family 26, member 7
chr4_-_119047180 2.27 ENSMUST00000150864.3
ENSMUST00000141227.9
erythroblast membrane-associated protein
chr10_-_116732813 2.23 ENSMUST00000048229.9
myelin regulatory factor-like
chr3_-_30194559 2.20 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr4_-_87724512 2.18 ENSMUST00000148059.2
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr2_+_68966125 2.15 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr2_-_60552980 2.14 ENSMUST00000028348.9
ENSMUST00000112517.8
integrin beta 6
chrX_-_104918911 2.11 ENSMUST00000200471.2
ATRX, chromatin remodeler
chr4_-_119047146 2.09 ENSMUST00000124626.9
erythroblast membrane-associated protein
chr16_-_43836681 2.06 ENSMUST00000036174.10
GRAM domain containing 1C
chr3_-_88460166 2.05 ENSMUST00000119002.2
ENSMUST00000029698.15
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr7_-_4606104 2.05 ENSMUST00000049113.14
protein tyrosine phosphatase, receptor type, H
chr3_+_89979948 2.02 ENSMUST00000121503.8
ENSMUST00000119570.8
tropomyosin 3, gamma
chr6_+_17306334 1.93 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr18_-_78166539 1.92 ENSMUST00000160292.8
solute carrier family 14 (urea transporter), member 1
chr18_+_89224219 1.91 ENSMUST00000236835.2
CD226 antigen
chr11_-_75060345 1.91 ENSMUST00000055619.5
hypermethylated in cancer 1
chr8_+_34582184 1.90 ENSMUST00000095345.5
membrane bound O-acyltransferase domain containing 4
chr8_-_40095706 1.88 ENSMUST00000210525.2
ENSMUST00000170091.3
macrophage scavenger receptor 1
chr10_+_39009951 1.80 ENSMUST00000019991.8
tubulin, epsilon 1
chr11_+_70529944 1.80 ENSMUST00000055184.7
ENSMUST00000108551.3
glycoprotein 1b, alpha polypeptide
chr7_+_80707328 1.79 ENSMUST00000107348.2
alpha-kinase 3
chr6_+_87405968 1.78 ENSMUST00000032125.7
bone morphogenetic protein 10
chr2_+_83786742 1.74 ENSMUST00000178325.2
predicted gene 13698
chr2_-_103133503 1.72 ENSMUST00000111176.9
ets homologous factor
chr11_+_118913788 1.72 ENSMUST00000026662.8
chromobox 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
8.3 33.1 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
7.1 42.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
6.8 20.5 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
5.4 16.2 GO:0002215 defense response to nematode(GO:0002215)
4.2 25.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
3.6 10.9 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
3.6 10.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
3.3 6.5 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
3.1 12.5 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
3.0 24.1 GO:0002432 granuloma formation(GO:0002432)
3.0 20.7 GO:2001205 negative regulation of osteoclast development(GO:2001205)
2.9 8.7 GO:0060540 lung lobe formation(GO:0060464) diaphragm morphogenesis(GO:0060540)
2.8 19.9 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
2.7 8.2 GO:0034378 chylomicron assembly(GO:0034378)
2.4 9.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
2.3 13.7 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
2.3 34.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
2.2 13.0 GO:0031133 regulation of axon diameter(GO:0031133)
2.1 32.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
2.0 6.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.0 20.3 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
2.0 23.9 GO:0001955 blood vessel maturation(GO:0001955)
1.9 16.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.8 8.8 GO:0060931 sinoatrial node cell development(GO:0060931)
1.7 15.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.5 4.4 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936)
1.4 4.1 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.3 37.7 GO:0020027 hemoglobin metabolic process(GO:0020027)
1.3 12.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.3 3.8 GO:0030221 basophil differentiation(GO:0030221)
1.1 2.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.1 5.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
1.1 6.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.1 20.7 GO:0016540 protein autoprocessing(GO:0016540)
1.1 10.7 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
1.0 3.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.0 20.9 GO:0008272 sulfate transport(GO:0008272)
0.9 15.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.9 2.7 GO:0070839 divalent metal ion export(GO:0070839)
0.9 3.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.9 114.6 GO:0007586 digestion(GO:0007586)
0.9 2.6 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.9 19.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.9 6.0 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.8 4.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.8 10.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.8 31.3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.7 2.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.6 14.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.6 5.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.6 6.0 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.6 5.3 GO:0030916 otic vesicle formation(GO:0030916)
0.6 2.9 GO:0009750 response to fructose(GO:0009750)
0.6 9.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.5 3.3 GO:1901582 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.5 2.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.5 3.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5 7.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 1.5 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.5 6.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.3 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.4 5.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 3.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 4.6 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.4 8.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.4 1.9 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.4 2.8 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.4 4.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.3 4.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 8.3 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.3 3.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 10.8 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 6.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 2.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.7 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.3 6.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 3.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 2.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 6.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 4.6 GO:0007379 segment specification(GO:0007379)
0.2 0.9 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.2 3.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.2 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.9 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 2.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.6 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 4.8 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 1.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 3.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 1.0 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 3.0 GO:0006833 water transport(GO:0006833)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 2.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 14.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 20.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.5 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 8.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 5.9 GO:0048566 embryonic digestive tract development(GO:0048566)
0.1 16.6 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 4.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.9 GO:0030168 platelet activation(GO:0030168)
0.1 5.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 8.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 2.7 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 4.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 19.4 GO:0006914 autophagy(GO:0006914)
0.0 11.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 2.8 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 10.4 GO:0006260 DNA replication(GO:0006260)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.9 GO:0006497 protein lipidation(GO:0006497)
0.0 0.1 GO:2001269 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 42.5 GO:1990584 cardiac Troponin complex(GO:1990584)
2.8 27.8 GO:0033093 Weibel-Palade body(GO:0033093)
2.5 12.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.3 3.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.2 13.4 GO:0045179 apical cortex(GO:0045179)
1.1 34.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 3.3 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.5 8.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.4 2.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 5.1 GO:0097512 cardiac myofibril(GO:0097512)
0.4 14.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 6.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 3.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 5.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 19.9 GO:0002102 podosome(GO:0002102)
0.3 4.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 3.4 GO:0042587 glycogen granule(GO:0042587)
0.3 0.9 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.3 2.1 GO:0071986 Ragulator complex(GO:0071986)
0.3 3.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 40.2 GO:0032993 protein-DNA complex(GO:0032993)
0.2 2.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 8.2 GO:0008305 integrin complex(GO:0008305)
0.2 4.1 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.8 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 4.4 GO:0031672 A band(GO:0031672)
0.1 26.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 5.7 GO:0045095 keratin filament(GO:0045095)
0.1 6.8 GO:0001533 cornified envelope(GO:0001533)
0.1 62.3 GO:0005925 focal adhesion(GO:0005925)
0.1 7.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 20.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.8 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 52.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 200.8 GO:0005615 extracellular space(GO:0005615)
0.1 7.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.7 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 4.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 3.3 GO:0005882 intermediate filament(GO:0005882)
0.1 20.5 GO:0000793 condensed chromosome(GO:0000793)
0.1 7.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 15.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 5.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 4.5 GO:0055037 recycling endosome(GO:0055037)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0005643 nuclear pore(GO:0005643)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.0 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 72.1 GO:0005576 extracellular region(GO:0005576)
0.0 1.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.5 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
6.1 42.5 GO:0030172 troponin C binding(GO:0030172)
5.1 15.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
4.2 12.5 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
2.9 25.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
2.6 31.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
2.5 12.7 GO:0004743 pyruvate kinase activity(GO:0004743)
2.4 26.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.2 6.5 GO:0071820 N-box binding(GO:0071820)
2.1 10.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.9 16.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.6 8.2 GO:0070051 fibrinogen binding(GO:0070051)
1.6 34.3 GO:0004806 triglyceride lipase activity(GO:0004806)
1.5 10.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.5 4.6 GO:0002113 interleukin-33 binding(GO:0002113)
1.5 13.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.5 10.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.5 13.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.4 19.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.3 40.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.2 20.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.1 33.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.1 3.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.1 6.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.1 6.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.9 29.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.8 3.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.6 20.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 37.9 GO:0050699 WW domain binding(GO:0050699)
0.6 5.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.6 4.3 GO:0015265 urea channel activity(GO:0015265)
0.6 20.2 GO:0001968 fibronectin binding(GO:0001968)
0.6 8.7 GO:0051525 NFAT protein binding(GO:0051525)
0.6 6.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 4.8 GO:0031849 olfactory receptor binding(GO:0031849)
0.5 8.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.5 1.5 GO:0070540 stearic acid binding(GO:0070540)
0.5 4.9 GO:0004064 arylesterase activity(GO:0004064)
0.5 3.3 GO:0015616 DNA translocase activity(GO:0015616)
0.5 105.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 2.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.4 7.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 17.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 1.0 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 2.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.3 2.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 9.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 20.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 1.8 GO:0031433 telethonin binding(GO:0031433)
0.2 4.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 5.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 3.1 GO:0038064 collagen receptor activity(GO:0038064)
0.2 0.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 36.0 GO:0005178 integrin binding(GO:0005178)
0.2 2.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 3.8 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 8.8 GO:0030552 cAMP binding(GO:0030552)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 8.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 4.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 2.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 6.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 8.1 GO:0043022 ribosome binding(GO:0043022)
0.1 22.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 15.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 9.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 6.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 4.4 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 2.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 7.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 5.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 46.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 0.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 28.9 GO:0008047 enzyme activator activity(GO:0008047)
0.0 1.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 11.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 2.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 19.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 2.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 4.1 GO:0003823 antigen binding(GO:0003823)
0.0 12.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 3.8 GO:0001664 G-protein coupled receptor binding(GO:0001664)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 24.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 37.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.5 40.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.4 6.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 35.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.4 5.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 27.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 16.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 27.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 10.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 25.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 6.0 PID IGF1 PATHWAY IGF1 pathway
0.2 19.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 7.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 30.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 7.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 32.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.7 41.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.6 23.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.4 25.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
1.2 57.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.7 14.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 8.7 REACTOME DEFENSINS Genes involved in Defensins
0.6 42.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 10.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 11.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.5 20.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.5 14.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 9.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 10.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 10.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.3 7.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 44.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 10.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 5.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 1.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 6.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 8.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 4.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 9.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 3.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage