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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Gcm1

Z-value: 0.56

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Transcription factors associated with Gcm1

Gene Symbol Gene ID Gene Info
Gcm1
ENSMUSG00000023333.9 Gcm1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm1mm39_v1_chr9_+_77959206_779592310.075.7e-01Click!

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_68013772 3.38 ENSMUST00000197515.2
ENSMUST00000103315.3
Igkv17-121
immunoglobulin kappa variable 17-121
chr7_-_100661181 3.28 ENSMUST00000178340.3
ENSMUST00000037540.5
P2ry2
purinergic receptor P2Y, G-protein coupled 2
chr8_-_3770642 3.00 ENSMUST00000062037.7
Clec4g
C-type lectin domain family 4, member g
chr6_-_70318437 2.88 ENSMUST00000196599.2
Igkv8-19
immunoglobulin kappa variable 8-19
chr11_+_101137231 2.58 ENSMUST00000122006.8
ENSMUST00000151830.2
Ramp2
receptor (calcitonin) activity modifying protein 2
chr6_-_70120881 2.57 ENSMUST00000103380.3
Igkv8-28
immunoglobulin kappa variable 8-28
chr11_+_101137786 2.56 ENSMUST00000107282.4
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_-_100661220 2.50 ENSMUST00000207916.2
P2ry2
purinergic receptor P2Y, G-protein coupled 2
chr2_-_34951443 2.37 ENSMUST00000028233.7
Hc
hemolytic complement
chr17_-_32408431 2.30 ENSMUST00000087721.10
ENSMUST00000162117.3
Ephx3
epoxide hydrolase 3
chr19_+_6450553 2.30 ENSMUST00000146831.8
ENSMUST00000035716.15
ENSMUST00000138555.8
ENSMUST00000167240.8
Rasgrp2
RAS, guanyl releasing protein 2
chr8_-_13304154 2.21 ENSMUST00000204916.3
ENSMUST00000033825.11
Adprhl1
ADP-ribosylhydrolase like 1
chr6_-_124698805 2.11 ENSMUST00000173315.8
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
chrX_-_74174608 2.05 ENSMUST00000033775.9
Mpp1
membrane protein, palmitoylated
chr16_+_65612083 2.01 ENSMUST00000168064.3
Vgll3
vestigial like family member 3
chrX_-_74174524 1.97 ENSMUST00000114091.8
Mpp1
membrane protein, palmitoylated
chr7_-_44785480 1.97 ENSMUST00000211246.2
ENSMUST00000210197.2
Flt3l
FMS-like tyrosine kinase 3 ligand
chr1_-_36578439 1.96 ENSMUST00000191849.6
Gm42417
predicted gene, 42417
chr19_+_6450641 1.88 ENSMUST00000113467.2
Rasgrp2
RAS, guanyl releasing protein 2
chr8_-_13304096 1.87 ENSMUST00000171619.2
Adprhl1
ADP-ribosylhydrolase like 1
chr16_+_65612394 1.83 ENSMUST00000227997.2
Vgll3
vestigial like family member 3
chr8_-_13304068 1.81 ENSMUST00000168498.8
Adprhl1
ADP-ribosylhydrolase like 1
chr17_+_23898633 1.71 ENSMUST00000233364.2
Cldn6
claudin 6
chr18_-_39620115 1.70 ENSMUST00000097592.9
ENSMUST00000115571.8
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr7_-_44785815 1.68 ENSMUST00000146760.7
Flt3l
FMS-like tyrosine kinase 3 ligand
chr7_-_30560989 1.67 ENSMUST00000052700.6
Ffar1
free fatty acid receptor 1
chr6_+_67532481 1.60 ENSMUST00000103302.3
Igkv2-137
immunoglobulin kappa chain variable 2-137
chr10_-_119948890 1.58 ENSMUST00000020449.12
Helb
helicase (DNA) B
chr17_+_64907697 1.47 ENSMUST00000086723.10
Man2a1
mannosidase 2, alpha 1
chr3_+_90173813 1.44 ENSMUST00000098914.10
Dennd4b
DENN/MADD domain containing 4B
chr12_-_73160181 1.44 ENSMUST00000043208.8
ENSMUST00000175693.3
Six4
sine oculis-related homeobox 4
chr17_+_23898223 1.41 ENSMUST00000024699.4
ENSMUST00000232719.2
Cldn6
claudin 6
chrX_+_7523499 1.39 ENSMUST00000033485.14
Prickle3
prickle planar cell polarity protein 3
chr2_+_127967951 1.36 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
chr7_-_44785709 1.34 ENSMUST00000211429.2
Flt3l
FMS-like tyrosine kinase 3 ligand
chr6_-_69394425 1.34 ENSMUST00000199160.2
Igkv4-61
immunoglobulin kappa chain variable 4-61
chr7_+_126895531 1.27 ENSMUST00000170971.8
Itgal
integrin alpha L
chr6_-_70313491 1.26 ENSMUST00000103388.4
Igkv6-20
immunoglobulin kappa variable 6-20
chr6_-_124613044 1.13 ENSMUST00000068797.3
ENSMUST00000218020.2
C1s2
complement component 1, s subcomponent 2
chr9_-_107482462 1.12 ENSMUST00000194433.6
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr9_-_107482494 1.07 ENSMUST00000102529.10
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr13_-_4573312 1.07 ENSMUST00000221564.2
ENSMUST00000078239.5
ENSMUST00000080361.13
Akr1c20
aldo-keto reductase family 1, member C20
chr16_-_36695166 1.07 ENSMUST00000075946.12
Eaf2
ELL associated factor 2
chr1_+_53352780 0.97 ENSMUST00000027265.10
ENSMUST00000114484.8
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr16_-_16687119 0.86 ENSMUST00000075017.5
Vpreb1
pre-B lymphocyte gene 1
chr14_+_32321341 0.85 ENSMUST00000187377.7
ENSMUST00000189022.8
ENSMUST00000186452.7
Prrxl1
paired related homeobox protein-like 1
chr14_+_32321824 0.83 ENSMUST00000068938.7
ENSMUST00000228878.2
Prrxl1
paired related homeobox protein-like 1
chr5_+_102872838 0.81 ENSMUST00000112853.8
Arhgap24
Rho GTPase activating protein 24
chr10_+_52265049 0.75 ENSMUST00000219730.2
Nepn
nephrocan
chrX_-_153999333 0.70 ENSMUST00000112551.4
Sat1
spermidine/spermine N1-acetyl transferase 1
chr3_+_138058139 0.69 ENSMUST00000090166.5
Adh6b
alcohol dehydrogenase 6B (class V)
chr7_+_78563513 0.68 ENSMUST00000038142.15
Isg20
interferon-stimulated protein
chr10_+_79984097 0.67 ENSMUST00000099492.10
ENSMUST00000042057.12
Midn
midnolin
chr2_+_105734975 0.66 ENSMUST00000037499.6
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr15_-_83135920 0.63 ENSMUST00000229687.2
ENSMUST00000164614.3
ENSMUST00000049530.14
A4galt
alpha 1,4-galactosyltransferase
chr14_+_55815879 0.63 ENSMUST00000174563.8
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_-_70564403 0.63 ENSMUST00000213380.2
ENSMUST00000049031.6
Mindy2
MINDY lysine 48 deubiquitinase 2
chr6_-_84564623 0.62 ENSMUST00000205228.3
Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr11_-_98040377 0.61 ENSMUST00000103143.10
Fbxl20
F-box and leucine-rich repeat protein 20
chr7_-_44646960 0.59 ENSMUST00000207443.2
ENSMUST00000207755.2
ENSMUST00000003290.12
Bcl2l12
BCL2-like 12 (proline rich)
chr12_+_8724129 0.56 ENSMUST00000111123.9
ENSMUST00000178015.8
ENSMUST00000020915.10
Pum2
pumilio RNA-binding family member 2
chr11_+_120382666 0.56 ENSMUST00000026899.4
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr14_+_55815817 0.56 ENSMUST00000174259.8
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr7_+_75879603 0.55 ENSMUST00000156166.8
Agbl1
ATP/GTP binding protein-like 1
chr11_-_75345482 0.54 ENSMUST00000173320.8
Wdr81
WD repeat domain 81
chr9_+_107457316 0.52 ENSMUST00000093785.6
Naa80
N(alpha)-acetyltransferase 80, NatH catalytic subunit
chr14_-_31923803 0.51 ENSMUST00000226683.2
ENSMUST00000170331.8
ENSMUST00000013845.13
Timm23
translocase of inner mitochondrial membrane 23
chr4_+_63477018 0.51 ENSMUST00000077709.11
Tmem268
transmembrane protein 268
chr2_-_39116457 0.49 ENSMUST00000028087.6
Ppp6c
protein phosphatase 6, catalytic subunit
chr12_+_8724220 0.47 ENSMUST00000111122.9
Pum2
pumilio RNA-binding family member 2
chr14_+_55815580 0.45 ENSMUST00000174484.8
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_-_52160816 0.44 ENSMUST00000134831.2
Hoxa3
homeobox A3
chr7_+_44647072 0.43 ENSMUST00000003284.16
ENSMUST00000209066.2
Irf3
interferon regulatory factor 3
chr16_+_17798292 0.39 ENSMUST00000075371.5
Vpreb2
pre-B lymphocyte gene 2
chr6_+_86342622 0.37 ENSMUST00000071492.9
Fam136a
family with sequence similarity 136, member A
chr5_+_114427227 0.34 ENSMUST00000169347.6
Myo1h
myosin 1H
chr10_-_71121083 0.34 ENSMUST00000020085.7
Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr13_+_55517545 0.33 ENSMUST00000063771.14
Rgs14
regulator of G-protein signaling 14
chr3_+_107137924 0.33 ENSMUST00000179399.3
A630076J17Rik
RIKEN cDNA A630076J17 gene
chr10_+_75399920 0.31 ENSMUST00000141062.8
ENSMUST00000152657.8
Ggt1
gamma-glutamyltransferase 1
chr1_-_43131598 0.30 ENSMUST00000188728.2
Tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr11_-_99433984 0.29 ENSMUST00000107443.8
ENSMUST00000074253.4
Krt40
keratin 40
chr4_-_42661893 0.28 ENSMUST00000108006.4
Il11ra2
interleukin 11 receptor, alpha chain 2
chr11_-_73089837 0.22 ENSMUST00000006103.9
ENSMUST00000108476.8
Ctns
cystinosis, nephropathic
chr7_+_104228831 0.21 ENSMUST00000098174.3
Olfr653
olfactory receptor 653
chr15_+_10249646 0.20 ENSMUST00000134410.8
Prlr
prolactin receptor
chr17_-_33007238 0.20 ENSMUST00000159086.10
Zfp871
zinc finger protein 871
chr2_+_174257597 0.18 ENSMUST00000109075.8
ENSMUST00000016397.7
Nelfcd
negative elongation factor complex member C/D, Th1l
chr3_-_102689986 0.18 ENSMUST00000029450.10
ENSMUST00000200041.5
Tshb
thyroid stimulating hormone, beta subunit
chr3_+_89366632 0.17 ENSMUST00000107410.8
Pmvk
phosphomevalonate kinase
chr7_-_44785603 0.16 ENSMUST00000209467.2
Gm45713
predicted gene 45713
chr3_-_102690026 0.15 ENSMUST00000172026.8
ENSMUST00000170856.6
Tshb
thyroid stimulating hormone, beta subunit
chr9_+_5345405 0.13 ENSMUST00000027009.11
Casp12
caspase 12
chr2_-_39116284 0.12 ENSMUST00000204701.3
Ppp6c
protein phosphatase 6, catalytic subunit
chr9_+_5345450 0.11 ENSMUST00000151332.2
Casp12
caspase 12
chr4_-_9669068 0.10 ENSMUST00000078139.13
ENSMUST00000108340.9
ENSMUST00000084915.11
ENSMUST00000108337.8
ENSMUST00000084912.12
ENSMUST00000038564.13
ENSMUST00000146441.8
ENSMUST00000098275.9
Asph
aspartate-beta-hydroxylase
chr7_-_105249308 0.10 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr19_+_46750016 0.09 ENSMUST00000099373.12
ENSMUST00000077666.6
Cnnm2
cyclin M2
chr2_-_39116044 0.08 ENSMUST00000204368.2
Ppp6c
protein phosphatase 6, catalytic subunit
chr16_+_36695479 0.05 ENSMUST00000023534.7
ENSMUST00000114812.9
ENSMUST00000134616.8
Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr2_-_105734829 0.05 ENSMUST00000122965.8
Elp4
elongator acetyltransferase complex subunit 4
chr8_+_91796767 0.05 ENSMUST00000209518.2
Rbl2
RB transcriptional corepressor like 2
chr10_-_74868360 0.04 ENSMUST00000159994.2
ENSMUST00000179546.8
ENSMUST00000160450.8
ENSMUST00000160072.8
ENSMUST00000009214.10
ENSMUST00000166088.8
Rsph14
radial spoke head homolog 14 (Chlamydomonas)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.8 5.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.6 5.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 5.8 GO:0060406 positive regulation of penile erection(GO:0060406)
0.5 2.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.4 1.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 1.4 GO:0061055 myotome development(GO:0061055)
0.3 1.4 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.3 2.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 3.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.4 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 0.6 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.6 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 4.0 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.7 GO:0021559 trigeminal nerve development(GO:0021559)
0.1 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.6 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 13.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.6 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 1.7 GO:0010524 positive regulation of calcium ion transport into cytosol(GO:0010524)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.4 1.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.3 1.6 GO:0008537 proteasome activator complex(GO:0008537)
0.3 2.4 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 1.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 5.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 3.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 4.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 5.8 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
1.5 5.9 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.9 5.1 GO:0097643 amylin receptor activity(GO:0097643)
0.5 1.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.3 1.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 1.7 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 1.6 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.3 1.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 0.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.7 GO:0019809 spermidine binding(GO:0019809)
0.2 2.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.6 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.1 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 3.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 5.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 2.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID EPO PATHWAY EPO signaling pathway
0.0 5.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 4.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 3.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 3.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling