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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Gli2

Z-value: 0.63

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Transcription factors associated with Gli2

Gene Symbol Gene ID Gene Info
Gli2
ENSMUSG00000048402.15 Gli2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli2mm39_v1_chr1_-_118981341_1189813680.334.2e-03Click!

Activity profile of Gli2 motif

Sorted Z-values of Gli2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_28240262 6.58 ENSMUST00000119180.4
Sycn
syncollin
chr16_+_4825216 5.63 ENSMUST00000185147.8
Smim22
small integral membrane protein 22
chr11_+_115802828 4.33 ENSMUST00000132961.2
Smim6
small integral membrane protein 6
chr5_-_53370761 3.82 ENSMUST00000031090.8
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_-_144292288 3.35 ENSMUST00000238848.2
ENSMUST00000118556.9
ENSMUST00000033393.15
Ano1
anoctamin 1, calcium activated chloride channel
chr18_+_35347983 2.88 ENSMUST00000235449.2
ENSMUST00000235269.2
Ctnna1
catenin (cadherin associated protein), alpha 1
chr11_+_96820220 2.71 ENSMUST00000062172.6
Prr15l
proline rich 15-like
chr11_+_96820091 2.65 ENSMUST00000054311.6
ENSMUST00000107636.4
Prr15l
proline rich 15-like
chr7_-_144292257 2.62 ENSMUST00000121758.8
Ano1
anoctamin 1, calcium activated chloride channel
chr5_+_117457126 2.59 ENSMUST00000111967.8
Vsig10
V-set and immunoglobulin domain containing 10
chr6_+_113448388 2.44 ENSMUST00000058300.14
Il17rc
interleukin 17 receptor C
chr5_+_117457356 2.40 ENSMUST00000086464.8
Vsig10
V-set and immunoglobulin domain containing 10
chr5_+_144127102 2.27 ENSMUST00000060747.8
Bhlha15
basic helix-loop-helix family, member a15
chr5_+_73563418 2.16 ENSMUST00000031040.13
ENSMUST00000065543.8
Cwh43
cell wall biogenesis 43 C-terminal homolog
chr11_-_103235475 2.14 ENSMUST00000041385.14
Arhgap27
Rho GTPase activating protein 27
chr9_+_44966464 2.05 ENSMUST00000114664.8
Mpzl3
myelin protein zero-like 3
chr8_-_27664651 1.98 ENSMUST00000054212.7
ENSMUST00000033878.14
ENSMUST00000209377.2
Rab11fip1
RAB11 family interacting protein 1 (class I)
chr16_+_19579651 1.83 ENSMUST00000119468.2
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_-_51955054 1.81 ENSMUST00000018561.14
ENSMUST00000114537.9
Myo1b
myosin IB
chr11_-_70924288 1.78 ENSMUST00000238695.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr7_+_101034604 1.69 ENSMUST00000130016.8
ENSMUST00000134143.2
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_-_139805661 1.67 ENSMUST00000147328.2
Tmem184a
transmembrane protein 184a
chr8_+_127790772 1.54 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
Pard3
par-3 family cell polarity regulator
chr6_-_72765935 1.51 ENSMUST00000114053.9
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr1_-_51955126 1.51 ENSMUST00000046390.14
Myo1b
myosin IB
chr7_-_65020955 1.47 ENSMUST00000102592.10
Tjp1
tight junction protein 1
chrX_+_99773523 1.43 ENSMUST00000019503.14
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chrX_+_99773784 1.43 ENSMUST00000113744.2
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_-_72766224 1.42 ENSMUST00000069536.12
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_-_137626207 1.38 ENSMUST00000134630.6
ENSMUST00000058210.13
ENSMUST00000111878.8
Eps8
epidermal growth factor receptor pathway substrate 8
chr12_+_58258558 1.30 ENSMUST00000110671.3
ENSMUST00000044299.3
Sstr1
somatostatin receptor 1
chr7_-_29204812 1.27 ENSMUST00000183096.8
ENSMUST00000085809.11
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr8_+_77628916 1.22 ENSMUST00000109912.8
ENSMUST00000128862.2
ENSMUST00000109911.8
Nr3c2
nuclear receptor subfamily 3, group C, member 2
chr5_-_18565353 1.15 ENSMUST00000074694.7
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr7_-_132724889 1.14 ENSMUST00000166439.8
Ctbp2
C-terminal binding protein 2
chr7_-_132725075 1.06 ENSMUST00000163601.8
ENSMUST00000033269.15
ENSMUST00000124096.8
Ctbp2
Fgfr2
C-terminal binding protein 2
fibroblast growth factor receptor 2
chr11_+_72686990 1.04 ENSMUST00000069395.7
ENSMUST00000172220.8
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr15_+_95688763 1.03 ENSMUST00000227791.2
Ano6
anoctamin 6
chrX_+_10351360 0.96 ENSMUST00000076354.13
ENSMUST00000115526.2
Tspan7
tetraspanin 7
chr4_+_120896582 0.94 ENSMUST00000030372.6
Col9a2
collagen, type IX, alpha 2
chr2_+_164327988 0.94 ENSMUST00000109350.9
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_72687080 0.93 ENSMUST00000207107.2
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chrX_-_73067514 0.91 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
Irak1
interleukin-1 receptor-associated kinase 1
chr4_+_43401232 0.90 ENSMUST00000125399.2
Rusc2
RUN and SH3 domain containing 2
chr7_-_132725137 0.86 ENSMUST00000170459.8
Ctbp2
C-terminal binding protein 2
chr9_+_114230144 0.86 ENSMUST00000063042.11
ENSMUST00000111820.4
Glb1
Tmppe
galactosidase, beta 1
transmembrane protein with metallophosphoesterase domain
chr6_+_137731526 0.83 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
Dera
deoxyribose-phosphate aldolase (putative)
chr2_+_117942357 0.81 ENSMUST00000039559.9
Thbs1
thrombospondin 1
chr8_+_127790626 0.80 ENSMUST00000162309.8
Pard3
par-3 family cell polarity regulator
chr5_+_145051090 0.78 ENSMUST00000196111.5
ENSMUST00000141602.2
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr2_+_164328375 0.76 ENSMUST00000069385.15
ENSMUST00000143690.8
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_46536088 0.76 ENSMUST00000102924.3
ENSMUST00000046897.13
Trim14
tripartite motif-containing 14
chrX_-_166165743 0.76 ENSMUST00000026839.5
Prps2
phosphoribosyl pyrophosphate synthetase 2
chr8_+_10056654 0.75 ENSMUST00000033892.9
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
chr11_+_70453666 0.74 ENSMUST00000072237.13
ENSMUST00000072873.14
Mink1
misshapen-like kinase 1 (zebrafish)
chr7_-_132724344 0.73 ENSMUST00000167218.8
Ctbp2
C-terminal binding protein 2
chr1_-_172418058 0.71 ENSMUST00000065679.8
Slamf8
SLAM family member 8
chr4_-_43499608 0.70 ENSMUST00000136005.3
ENSMUST00000054538.13
Arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr7_-_65020655 0.70 ENSMUST00000032729.8
Tjp1
tight junction protein 1
chr5_+_145051025 0.69 ENSMUST00000085679.13
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr3_+_97536120 0.66 ENSMUST00000107050.8
ENSMUST00000029729.15
ENSMUST00000107049.2
Fmo5
flavin containing monooxygenase 5
chr17_+_45874800 0.66 ENSMUST00000224905.2
ENSMUST00000226086.2
ENSMUST00000041353.7
Slc35b2
solute carrier family 35, member B2
chr6_+_137731599 0.65 ENSMUST00000204356.2
Dera
deoxyribose-phosphate aldolase (putative)
chr17_+_24851647 0.64 ENSMUST00000047611.4
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr11_+_70453724 0.64 ENSMUST00000102559.11
Mink1
misshapen-like kinase 1 (zebrafish)
chr3_-_135313982 0.62 ENSMUST00000132668.8
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr15_+_95688712 0.62 ENSMUST00000071874.8
Ano6
anoctamin 6
chr7_-_97970388 0.61 ENSMUST00000120520.8
Acer3
alkaline ceramidase 3
chr9_+_100956145 0.61 ENSMUST00000189616.2
Msl2
MSL complex subunit 2
chr13_-_54759086 0.61 ENSMUST00000049575.8
Cltb
clathrin, light polypeptide (Lcb)
chrX_-_9529189 0.56 ENSMUST00000033519.3
Dynlt3
dynein light chain Tctex-type 3
chr7_-_132725041 0.55 ENSMUST00000171022.8
Ctbp2
C-terminal binding protein 2
chr13_+_13612136 0.54 ENSMUST00000005532.9
Nid1
nidogen 1
chr8_+_10056631 0.53 ENSMUST00000207792.3
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
chr13_-_54759145 0.51 ENSMUST00000091609.11
Cltb
clathrin, light polypeptide (Lcb)
chr7_+_40547608 0.48 ENSMUST00000044705.12
Vstm2b
V-set and transmembrane domain containing 2B
chr9_+_100525807 0.47 ENSMUST00000133388.2
Stag1
stromal antigen 1
chr2_+_74566740 0.46 ENSMUST00000111982.8
Hoxd3
homeobox D3
chr6_-_38614155 0.46 ENSMUST00000096030.7
ENSMUST00000201345.2
Klrg2
killer cell lectin-like receptor subfamily G, member 2
chr1_-_93406091 0.44 ENSMUST00000188165.2
Hdlbp
high density lipoprotein (HDL) binding protein
chr17_-_24851549 0.43 ENSMUST00000227607.2
ENSMUST00000227509.2
ENSMUST00000227745.2
Tsc2
TSC complex subunit 2
chr18_+_61688329 0.42 ENSMUST00000165123.8
Csnk1a1
casein kinase 1, alpha 1
chr11_+_100510043 0.42 ENSMUST00000107376.8
Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr2_-_37593287 0.40 ENSMUST00000072186.12
Strbp
spermatid perinuclear RNA binding protein
chr14_+_51162425 0.39 ENSMUST00000049411.12
ENSMUST00000136753.8
ENSMUST00000154288.3
Apex1
apurinic/apyrimidinic endonuclease 1
chr1_-_72576089 0.38 ENSMUST00000047786.6
Marchf4
membrane associated ring-CH-type finger 4
chr4_-_150039486 0.38 ENSMUST00000038562.9
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_-_56557920 0.38 ENSMUST00000050544.8
Has2
hyaluronan synthase 2
chr8_+_85786684 0.37 ENSMUST00000095220.4
Fbxw9
F-box and WD-40 domain protein 9
chr17_-_56916771 0.37 ENSMUST00000052832.6
Micos13
mitochondrial contact site and cristae organizing system subunit 13
chr9_+_62249730 0.37 ENSMUST00000156461.2
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_-_82939330 0.37 ENSMUST00000071708.12
Frem1
Fras1 related extracellular matrix protein 1
chrX_+_160500051 0.35 ENSMUST00000112338.2
Rai2
retinoic acid induced 2
chr9_+_13573756 0.34 ENSMUST00000177755.3
Maml2
mastermind like transcriptional coactivator 2
chr11_+_29476385 0.34 ENSMUST00000133452.8
Mtif2
mitochondrial translational initiation factor 2
chr4_+_41760454 0.34 ENSMUST00000108040.8
Il11ra1
interleukin 11 receptor, alpha chain 1
chr8_+_91635192 0.33 ENSMUST00000211403.2
Chd9
chromodomain helicase DNA binding protein 9
chr5_+_147206769 0.33 ENSMUST00000085591.7
Pdx1
pancreatic and duodenal homeobox 1
chr2_+_130116357 0.33 ENSMUST00000136621.9
ENSMUST00000141872.2
Nop56
NOP56 ribonucleoprotein
chr5_-_115438971 0.32 ENSMUST00000112090.2
Dynll1
dynein light chain LC8-type 1
chr12_-_32000169 0.32 ENSMUST00000176520.8
Hbp1
high mobility group box transcription factor 1
chr17_-_84495364 0.31 ENSMUST00000060366.7
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr11_+_70453806 0.31 ENSMUST00000079244.12
ENSMUST00000102558.11
Mink1
misshapen-like kinase 1 (zebrafish)
chr11_+_117198958 0.31 ENSMUST00000153668.8
Septin9
septin 9
chr1_-_93406515 0.31 ENSMUST00000170883.8
ENSMUST00000189025.7
Hdlbp
high density lipoprotein (HDL) binding protein
chr11_+_101066867 0.30 ENSMUST00000103109.4
Cntnap1
contactin associated protein-like 1
chr16_+_8647959 0.26 ENSMUST00000023150.7
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr18_+_61688378 0.25 ENSMUST00000165721.8
ENSMUST00000115246.9
ENSMUST00000166990.8
ENSMUST00000163205.8
ENSMUST00000170862.8
Csnk1a1
casein kinase 1, alpha 1
chr2_+_120439858 0.24 ENSMUST00000124187.8
Haus2
HAUS augmin-like complex, subunit 2
chr2_+_85600147 0.24 ENSMUST00000065626.3
Olfr1013
olfactory receptor 1013
chr17_-_25716189 0.23 ENSMUST00000165183.10
ENSMUST00000051864.5
Sstr5
somatostatin receptor 5
chr9_+_107454114 0.23 ENSMUST00000112387.9
ENSMUST00000123005.8
ENSMUST00000010195.14
ENSMUST00000144392.2
Hyal1
hyaluronoglucosaminidase 1
chr14_-_65187287 0.23 ENSMUST00000067843.10
ENSMUST00000176489.8
ENSMUST00000175905.8
ENSMUST00000022544.14
ENSMUST00000175744.8
ENSMUST00000176128.8
Hmbox1
homeobox containing 1
chrX_+_160500623 0.23 ENSMUST00000061514.8
Rai2
retinoic acid induced 2
chr11_-_121279062 0.22 ENSMUST00000106107.3
Rab40b
Rab40B, member RAS oncogene family
chr5_-_92231517 0.22 ENSMUST00000202258.4
ENSMUST00000113127.7
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr10_-_93425553 0.21 ENSMUST00000020203.7
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr14_-_55354392 0.21 ENSMUST00000022819.13
Jph4
junctophilin 4
chr6_+_134897473 0.21 ENSMUST00000204807.2
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr6_+_134897364 0.20 ENSMUST00000067327.11
ENSMUST00000003115.9
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr6_+_135175031 0.20 ENSMUST00000130612.2
Fam234b
family with sequence similarity 234, member B
chr12_-_32000209 0.20 ENSMUST00000176084.2
ENSMUST00000176103.8
ENSMUST00000167458.9
Hbp1
high mobility group box transcription factor 1
chr2_+_84867783 0.20 ENSMUST00000168266.8
ENSMUST00000130729.3
Ssrp1
structure specific recognition protein 1
chr9_+_100525501 0.19 ENSMUST00000146312.8
ENSMUST00000129269.8
Stag1
stromal antigen 1
chr14_+_51162635 0.18 ENSMUST00000128395.2
Apex1
apurinic/apyrimidinic endonuclease 1
chr17_-_54605479 0.17 ENSMUST00000233758.2
Slc5a7
solute carrier family 5 (choline transporter), member 7
chr1_-_175453117 0.17 ENSMUST00000027810.14
Fh1
fumarate hydratase 1
chr14_+_65187485 0.16 ENSMUST00000043914.8
ENSMUST00000239450.2
Ints9
integrator complex subunit 9
chr9_+_108924457 0.16 ENSMUST00000072093.13
Plxnb1
plexin B1
chr11_+_115921129 0.15 ENSMUST00000021116.12
ENSMUST00000106452.2
Unk
unkempt family zinc finger
chr2_+_130116344 0.14 ENSMUST00000103198.11
Nop56
NOP56 ribonucleoprotein
chrX_-_140508177 0.13 ENSMUST00000067841.8
Irs4
insulin receptor substrate 4
chr11_+_29476423 0.13 ENSMUST00000136351.8
ENSMUST00000020749.13
ENSMUST00000144321.8
ENSMUST00000093239.11
Mtif2
mitochondrial translational initiation factor 2
chr9_+_100525637 0.12 ENSMUST00000041418.13
Stag1
stromal antigen 1
chr2_+_69691982 0.12 ENSMUST00000112260.3
Ssb
Sjogren syndrome antigen B
chrX_-_95000496 0.11 ENSMUST00000079987.13
ENSMUST00000113864.3
Las1l
LAS1-like (S. cerevisiae)
chr10_-_18890281 0.09 ENSMUST00000146388.2
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr11_-_100510423 0.09 ENSMUST00000137688.9
ENSMUST00000239389.2
ENSMUST00000155152.9
ENSMUST00000154972.9
ENSMUST00000239479.2
ENSMUST00000132886.3
Dnajc7
DnaJ heat shock protein family (Hsp40) member C7
chrX_+_7439839 0.09 ENSMUST00000144719.9
ENSMUST00000234896.2
Flicr
Foxp3
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr17_-_24428351 0.08 ENSMUST00000024931.6
Ntn3
netrin 3
chr9_-_107648144 0.08 ENSMUST00000183248.3
ENSMUST00000182022.8
ENSMUST00000035199.13
ENSMUST00000182659.8
Rbm5
RNA binding motif protein 5
chr2_-_121211410 0.08 ENSMUST00000038389.15
Strc
stereocilin
chr1_+_55127110 0.08 ENSMUST00000075242.7
Hspe1
heat shock protein 1 (chaperonin 10)
chr14_-_51162083 0.07 ENSMUST00000160375.8
ENSMUST00000162177.8
Osgep
O-sialoglycoprotein endopeptidase
chr4_-_119151717 0.07 ENSMUST00000079644.13
Ybx1
Y box protein 1
chr16_+_3648742 0.07 ENSMUST00000214238.2
ENSMUST00000214590.2
Olfr15
olfactory receptor 15
chr2_-_157408239 0.07 ENSMUST00000109528.9
ENSMUST00000088494.3
Blcap
bladder cancer associated protein
chr9_-_108455899 0.06 ENSMUST00000068700.7
Wdr6
WD repeat domain 6
chr19_+_6952319 0.05 ENSMUST00000070850.8
Ppp1r14b
protein phosphatase 1, regulatory inhibitor subunit 14B
chr7_-_30349548 0.05 ENSMUST00000108141.2
ENSMUST00000042726.14
Rbm42
RNA binding motif protein 42
chr12_+_38830081 0.04 ENSMUST00000095767.11
Etv1
ets variant 1
chr14_-_51162346 0.03 ENSMUST00000159292.8
Osgep
O-sialoglycoprotein endopeptidase
chr2_+_158636727 0.02 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr17_+_28910393 0.02 ENSMUST00000124886.9
ENSMUST00000114758.9
Mapk14
mitogen-activated protein kinase 14
chr10_+_83379805 0.01 ENSMUST00000038388.7
Washc4
WASH complex subunit 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.5 1.6 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.5 6.0 GO:0015705 iodide transport(GO:0015705)
0.5 2.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 1.1 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.3 1.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 2.3 GO:0003383 apical constriction(GO:0003383)
0.3 2.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 1.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 1.7 GO:0018992 germ-line sex determination(GO:0018992)
0.3 3.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 0.8 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.2 1.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.7 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.2 0.6 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 0.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
0.2 1.3 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.2 2.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.8 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 2.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 2.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 2.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.7 GO:0045060 negative thymic T cell selection(GO:0045060)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.7 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.2 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 1.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.6 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 1.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.0 2.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 0.1 GO:0002851 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 3.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.8 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0046697 decidualization(GO:0046697)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 2.3 GO:0033269 internode region of axon(GO:0033269)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 2.9 GO:0005915 zonula adherens(GO:0005915)
0.2 0.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 4.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 8.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.8 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.6 1.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 4.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 1.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 2.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.7 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 0.8 GO:0070052 collagen V binding(GO:0070052)
0.2 0.6 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.2 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.2 GO:0071253 connexin binding(GO:0071253)
0.2 0.6 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 7.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 2.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 7.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 2.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle