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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Glis3

Z-value: 0.96

Motif logo

Transcription factors associated with Glis3

Gene Symbol Gene ID Gene Info
ENSMUSG00000052942.14 Glis3
ENSMUSG00000052942.14 Glis3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Glis3mm39_v1_chr19_-_28657477_286575230.084.9e-01Click!

Activity profile of Glis3 motif

Sorted Z-values of Glis3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_113883285 7.56 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr9_-_110571645 5.61 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr6_+_108637577 5.37 ENSMUST00000032194.11
basic helix-loop-helix family, member e40
chr9_-_50663648 5.20 ENSMUST00000217159.2
heat shock protein 2
chr9_-_50663571 4.93 ENSMUST00000042790.5
heat shock protein 2
chr11_-_106240215 4.87 ENSMUST00000021056.8
sodium channel, voltage-gated, type IV, alpha
chr7_+_44667377 4.66 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr7_-_19504446 4.52 ENSMUST00000003061.14
basal cell adhesion molecule
chr2_+_74566740 4.32 ENSMUST00000111982.8
homeobox D3
chr17_-_24866749 4.20 ENSMUST00000234121.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr9_+_50663171 3.91 ENSMUST00000214609.2
crystallin, alpha B
chr19_-_6964988 3.85 ENSMUST00000130048.8
ENSMUST00000025914.7
vascular endothelial growth factor B
chr2_+_32536594 3.79 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr1_-_168259264 3.37 ENSMUST00000176790.8
pre B cell leukemia homeobox 1
chr6_+_17463748 3.09 ENSMUST00000115443.8
met proto-oncogene
chr1_-_168259465 3.03 ENSMUST00000176540.8
pre B cell leukemia homeobox 1
chrX_+_104807868 2.95 ENSMUST00000033581.4
fibroblast growth factor 16
chr6_+_88175312 2.92 ENSMUST00000203480.2
ENSMUST00000015197.9
GATA binding protein 2
chr11_-_88609048 2.87 ENSMUST00000107909.8
musashi RNA-binding protein 2
chr1_-_168259710 2.79 ENSMUST00000072863.6
pre B cell leukemia homeobox 1
chrX_-_23231245 2.75 ENSMUST00000115313.8
kelch-like 13
chr14_+_55798517 2.73 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr4_+_144619397 2.71 ENSMUST00000105744.8
ENSMUST00000171001.8
dehydrogenase/reductase (SDR family) member 3
chr11_+_96162283 2.70 ENSMUST00000000010.9
ENSMUST00000174042.3
homeobox B9
chr1_-_168259839 2.65 ENSMUST00000188912.7
pre B cell leukemia homeobox 1
chr9_-_48747232 2.58 ENSMUST00000093852.5
zinc finger and BTB domain containing 16
chr14_+_55797934 2.54 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr6_-_52222776 2.49 ENSMUST00000048026.10
homeobox A11
chr6_+_17463819 2.45 ENSMUST00000140070.8
met proto-oncogene
chr4_-_120604445 2.42 ENSMUST00000030376.8
potassium voltage-gated channel, subfamily Q, member 4
chr11_-_88608958 2.40 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr1_-_168259070 2.37 ENSMUST00000064438.11
pre B cell leukemia homeobox 1
chr11_-_115310743 2.34 ENSMUST00000106537.8
ENSMUST00000043931.9
ENSMUST00000073791.10
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
chr14_+_55798362 2.31 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr4_+_144619647 2.28 ENSMUST00000154208.8
dehydrogenase/reductase (SDR family) member 3
chr6_+_17463925 2.27 ENSMUST00000115442.8
met proto-oncogene
chr4_+_144619696 2.24 ENSMUST00000142808.8
dehydrogenase/reductase (SDR family) member 3
chr9_-_48747474 2.24 ENSMUST00000216150.2
zinc finger and BTB domain containing 16
chr2_-_75534985 2.23 ENSMUST00000102672.5
nuclear factor, erythroid derived 2, like 2
chr4_+_119112590 2.14 ENSMUST00000084309.12
claudin 19
chr9_-_108183356 2.09 ENSMUST00000192886.6
T cell leukemia translocation altered gene
chr4_+_63133639 2.03 ENSMUST00000036300.13
collagen, type XXVII, alpha 1
chr15_+_89383799 2.01 ENSMUST00000109309.9
SH3 and multiple ankyrin repeat domains 3
chr6_+_108637816 1.99 ENSMUST00000163617.2
basic helix-loop-helix family, member e40
chr5_-_91550853 1.99 ENSMUST00000121044.6
betacellulin, epidermal growth factor family member
chr9_-_108183162 1.99 ENSMUST00000044725.9
T cell leukemia translocation altered gene
chrM_+_8603 1.92 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr5_-_34345014 1.90 ENSMUST00000042701.13
ENSMUST00000119171.2
Max dimerization protein 4
chr3_+_104696342 1.90 ENSMUST00000106787.8
ENSMUST00000176347.6
ras homolog family member C
chr4_+_119112692 1.85 ENSMUST00000094823.4
claudin 19
chr7_+_27291126 1.83 ENSMUST00000167435.8
thymoma viral proto-oncogene 2
chr10_-_13350106 1.82 ENSMUST00000105545.12
phosphatase and actin regulator 2
chr9_-_108183140 1.81 ENSMUST00000195615.2
T cell leukemia translocation altered gene
chr11_-_5848771 1.80 ENSMUST00000102921.4
myosin, light polypeptide 7, regulatory
chr15_+_102314809 1.72 ENSMUST00000001326.7
trans-acting transcription factor 1
chr15_+_102314578 1.72 ENSMUST00000170884.8
ENSMUST00000163709.8
trans-acting transcription factor 1
chr3_+_104696108 1.71 ENSMUST00000002303.12
ras homolog family member C
chr6_-_72876686 1.70 ENSMUST00000206378.2
potassium channel modulatory factor 1
chr4_+_85972125 1.60 ENSMUST00000107178.9
ENSMUST00000048885.12
ENSMUST00000141889.8
ENSMUST00000120678.2
ADAMTS-like 1
chr11_-_88608920 1.58 ENSMUST00000092794.12
musashi RNA-binding protein 2
chr7_+_27290969 1.57 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr14_-_52151026 1.51 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr2_-_160714473 1.50 ENSMUST00000103111.9
zinc fingers and homeoboxes 3
chr15_+_102829538 1.48 ENSMUST00000001700.7
homeobox C13
chr11_-_70128462 1.48 ENSMUST00000100950.10
RIKEN cDNA 0610010K14 gene
chrX_-_141749704 1.47 ENSMUST00000041317.3
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_-_49286594 1.46 ENSMUST00000032717.7
developing brain homeobox 1
chr6_-_72876882 1.45 ENSMUST00000068697.11
potassium channel modulatory factor 1
chr3_+_68401536 1.44 ENSMUST00000182719.8
schwannomin interacting protein 1
chr16_+_22713593 1.42 ENSMUST00000232674.2
alpha-2-HS-glycoprotein
chr8_+_106002772 1.38 ENSMUST00000014920.8
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr13_+_119565118 1.34 ENSMUST00000109203.9
polyadenylate binding protein-interacting protein 1
chr11_-_33097400 1.29 ENSMUST00000020507.8
fibroblast growth factor 18
chr8_-_88686188 1.28 ENSMUST00000109655.9
zinc finger protein 423
chr16_-_50252703 1.23 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr4_+_118285275 1.23 ENSMUST00000006557.13
ENSMUST00000167636.8
ENSMUST00000102673.11
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr1_+_166829001 1.22 ENSMUST00000126198.3
family with sequence similarity 78, member B
chr8_+_23464860 1.21 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr3_+_121220146 1.13 ENSMUST00000029773.13
calponin 3, acidic
chr3_+_52175757 1.12 ENSMUST00000053764.7
forkhead box O1
chr11_-_51891575 1.09 ENSMUST00000109086.8
ubiquitin-conjugating enzyme E2B
chr10_-_120312374 1.08 ENSMUST00000072777.14
ENSMUST00000159699.2
high mobility group AT-hook 2
chr11_-_51891259 1.07 ENSMUST00000020657.13
ubiquitin-conjugating enzyme E2B
chr8_+_109441276 1.07 ENSMUST00000043896.10
zinc finger homeobox 3
chr2_+_4886298 1.05 ENSMUST00000027973.14
selenophosphate synthetase 1
chr7_+_89779564 1.01 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr15_-_50753437 1.00 ENSMUST00000077935.6
transcriptional repressor GATA binding 1
chr19_-_47303184 0.98 ENSMUST00000237796.2
SH3 and PX domains 2A
chrX_+_100298134 0.96 ENSMUST00000062000.6
forkhead box O4
chr2_-_160714904 0.95 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr3_-_142587419 0.94 ENSMUST00000174422.8
ENSMUST00000173830.8
protein kinase N2
chr7_+_89779493 0.94 ENSMUST00000208730.2
phosphatidylinositol binding clathrin assembly protein
chr16_+_20492014 0.94 ENSMUST00000154950.8
ENSMUST00000115461.8
ENSMUST00000136713.5
eukaryotic translation initiation factor 4, gamma 1
chr13_+_119565424 0.89 ENSMUST00000026520.14
polyadenylate binding protein-interacting protein 1
chr7_-_46445305 0.89 ENSMUST00000107653.8
ENSMUST00000107654.8
ENSMUST00000014562.14
ENSMUST00000152759.8
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr6_+_85164420 0.88 ENSMUST00000045942.9
empty spiracles homeobox 1
chr9_+_118755521 0.88 ENSMUST00000073109.12
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr7_+_79676095 0.87 ENSMUST00000206039.2
zinc finger protein 710
chr11_+_100510043 0.86 ENSMUST00000107376.8
NFKB inhibitor interacting Ras-like protein 2
chr11_+_57692399 0.75 ENSMUST00000020826.6
SAP30-like
chr15_-_75760602 0.74 ENSMUST00000184858.2
maestro heat-like repeat family member 6
chr17_-_85097945 0.72 ENSMUST00000112308.9
leucine-rich PPR-motif containing
chr13_+_119565669 0.72 ENSMUST00000173627.8
ENSMUST00000126957.9
ENSMUST00000174691.8
polyadenylate binding protein-interacting protein 1
chr11_-_72380730 0.71 ENSMUST00000045303.10
spinster homolog 2
chr9_+_95441652 0.71 ENSMUST00000079597.7
progestin and adipoQ receptor family member IX
chr10_+_63293284 0.69 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr7_-_46445085 0.68 ENSMUST00000123725.2
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr1_-_84816379 0.64 ENSMUST00000187818.2
thyroid hormone receptor interactor 12
chr2_+_174171979 0.64 ENSMUST00000109083.2
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_-_160714749 0.62 ENSMUST00000176141.8
zinc fingers and homeoboxes 3
chr7_+_89779421 0.61 ENSMUST00000207225.2
ENSMUST00000207484.2
ENSMUST00000209068.2
phosphatidylinositol binding clathrin assembly protein
chr13_-_103911092 0.61 ENSMUST00000074616.7
splicing regulatory glutamine/lysine-rich protein 1
chr10_-_62723103 0.59 ENSMUST00000218438.2
tet methylcytosine dioxygenase 1
chr13_-_40883893 0.59 ENSMUST00000021787.7
transcription factor AP-2, alpha
chr19_+_60878802 0.54 ENSMUST00000236876.2
G protein-coupled receptor kinase 5
chr17_-_34250616 0.54 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr13_+_38009981 0.54 ENSMUST00000110238.10
ras responsive element binding protein 1
chr7_-_109271171 0.53 ENSMUST00000208734.2
DENN domain containing 2B
chr13_-_63721412 0.51 ENSMUST00000195106.2
patched 1
chr11_-_115427007 0.50 ENSMUST00000118155.8
ENSMUST00000153892.2
small ubiquitin-like modifier 2
chr14_+_53257873 0.47 ENSMUST00000196756.2
T cell receptor alpha variable 7D-6
chr13_+_120151915 0.46 ENSMUST00000225543.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr9_+_21279802 0.45 ENSMUST00000214474.2
interleukin enhancer binding factor 3
chr1_-_84817000 0.45 ENSMUST00000186648.7
thyroid hormone receptor interactor 12
chr9_+_54672032 0.44 ENSMUST00000034830.9
cellular retinoic acid binding protein I
chr3_-_142587678 0.43 ENSMUST00000043812.15
protein kinase N2
chr17_-_81035453 0.42 ENSMUST00000234133.2
ENSMUST00000112389.9
ENSMUST00000025089.9
mitogen-activated protein kinase kinase kinase kinase 3
chr5_-_21260878 0.42 ENSMUST00000030556.8
protein tyrosine phosphatase, non-receptor type 12
chr18_+_34910064 0.42 ENSMUST00000043775.9
ENSMUST00000224715.2
KDM3B lysine (K)-specific demethylase 3B
chr15_+_27466732 0.42 ENSMUST00000022875.7
progressive ankylosis
chrX_-_103244728 0.40 ENSMUST00000056502.7
neurite extension and migration factor
chr10_-_68114543 0.39 ENSMUST00000219238.2
AT rich interactive domain 5B (MRF1-like)
chr7_-_142211203 0.38 ENSMUST00000097936.9
ENSMUST00000000033.12
insulin-like growth factor 2
chrX_+_47430221 0.36 ENSMUST00000136348.8
BCL6 co-repressor-like 1
chr10_-_43934774 0.36 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr19_+_8919228 0.35 ENSMUST00000096240.3
metastasis-associated gene family, member 2
chr16_+_20492267 0.33 ENSMUST00000115460.8
eukaryotic translation initiation factor 4, gamma 1
chr5_-_29683468 0.33 ENSMUST00000165512.4
ENSMUST00000001608.8
motor neuron and pancreas homeobox 1
chr16_-_4376471 0.32 ENSMUST00000230875.2
transcription factor AP4
chr1_+_166828982 0.31 ENSMUST00000165874.8
ENSMUST00000190081.7
family with sequence similarity 78, member B
chr7_+_18659787 0.31 ENSMUST00000032571.10
ENSMUST00000220302.2
NOVA alternative splicing regulator 2
chr17_-_34250474 0.30 ENSMUST00000171872.3
ENSMUST00000025186.16
solute carrier family 39 (zinc transporter), member 7
chr15_+_89384317 0.30 ENSMUST00000135214.2
SH3 and multiple ankyrin repeat domains 3
chrX_-_93166992 0.29 ENSMUST00000088102.12
ENSMUST00000113927.8
zinc finger protein X-linked
chrX_-_93166964 0.25 ENSMUST00000137853.8
zinc finger protein X-linked
chr6_+_99669640 0.25 ENSMUST00000101122.3
G protein-coupled receptor 27
chr11_+_115310963 0.21 ENSMUST00000106533.8
ENSMUST00000123345.2
potassium channel tetramerisation domain containing 2
chr9_+_106247943 0.21 ENSMUST00000173748.2
dual specificity phosphatase 7
chr7_+_46445512 0.21 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr7_+_126380655 0.20 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chrX_-_93585668 0.20 ENSMUST00000026142.8
MAGE family member D1
chr15_+_102315579 0.19 ENSMUST00000169619.2
trans-acting transcription factor 1
chr15_-_50753792 0.19 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr11_+_115310885 0.19 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2
chr9_+_106083988 0.18 ENSMUST00000188650.2
twinfilin actin binding protein 2
chr2_-_152673032 0.18 ENSMUST00000128172.3
BCL2-like 1
chr13_+_38009951 0.17 ENSMUST00000138043.8
ras responsive element binding protein 1
chr15_-_97902515 0.16 ENSMUST00000088355.12
collagen, type II, alpha 1
chr17_+_35191661 0.15 ENSMUST00000007248.5
heat shock protein 1-like
chr11_-_70128587 0.14 ENSMUST00000108576.10
RIKEN cDNA 0610010K14 gene
chr4_-_133746138 0.14 ENSMUST00000051674.3
lin-28 homolog A (C. elegans)
chr3_+_89153258 0.13 ENSMUST00000040888.12
keratinocyte associated protein 2
chr19_+_41471395 0.12 ENSMUST00000237208.2
ENSMUST00000238398.2
ligand dependent nuclear receptor corepressor
chr1_-_135615831 0.11 ENSMUST00000190298.8
neuron navigator 1
chr4_+_137004793 0.09 ENSMUST00000045747.5
wingless-type MMTV integration site family, member 4
chr11_-_115426618 0.08 ENSMUST00000121185.8
ENSMUST00000117589.8
small ubiquitin-like modifier 2
chr2_-_168584020 0.08 ENSMUST00000109177.8
ATPase, class II, type 9A
chr18_-_78249612 0.07 ENSMUST00000163367.3
solute carrier family 14 (urea transporter), member 2
chr9_+_107805647 0.07 ENSMUST00000085073.2
actin-like 11
chr15_-_97902576 0.06 ENSMUST00000023123.15
collagen, type II, alpha 1
chr11_+_115921129 0.03 ENSMUST00000021116.12
ENSMUST00000106452.2
unkempt family zinc finger
chr7_+_5023375 0.03 ENSMUST00000076251.7
zinc finger protein 865

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
1.2 3.6 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
1.1 7.8 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.9 10.1 GO:0007525 somatic muscle development(GO:0007525)
0.8 3.8 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.7 2.2 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.7 2.9 GO:0035854 eosinophil fate commitment(GO:0035854)
0.7 4.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.7 2.2 GO:0033128 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.7 7.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.6 4.9 GO:0015871 choline transport(GO:0015871)
0.6 4.2 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6 3.4 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.5 4.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 6.9 GO:0072675 osteoclast fusion(GO:0072675)
0.5 2.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.5 1.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.4 2.6 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.4 14.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.4 3.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 7.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 1.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 5.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3 2.0 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.3 4.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 2.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 6.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 1.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.2 1.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 0.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 2.7 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 3.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.4 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 3.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 1.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 1.5 GO:0060613 fat pad development(GO:0060613)
0.1 2.0 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 1.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0010157 response to chlorate(GO:0010157)
0.1 6.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 2.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 1.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 1.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 1.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 4.8 GO:0048864 stem cell development(GO:0048864)
0.0 0.6 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 0.5 GO:0060746 parental behavior(GO:0060746)
0.0 4.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.7 GO:0030879 mammary gland development(GO:0030879)
0.0 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0042643 actomyosin, actin portion(GO:0042643)
0.4 1.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 2.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 2.2 GO:0033503 HULC complex(GO:0033503)
0.2 3.9 GO:0097512 cardiac myofibril(GO:0097512)
0.2 4.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 3.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 7.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 2.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 7.7 GO:0005844 polysome(GO:0005844)
0.1 1.3 GO:0016589 NURF complex(GO:0016589)
0.1 8.0 GO:0032420 stereocilium(GO:0032420)
0.1 7.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 17.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 4.3 GO:0016235 aggresome(GO:0016235)
0.1 8.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 5.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0005916 fascia adherens(GO:0005916)
0.0 3.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.0 4.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 5.4 GO:0043296 apical junction complex(GO:0043296)
0.0 5.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.3 3.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.0 7.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 5.6 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.7 7.4 GO:0043426 MRF binding(GO:0043426)
0.5 3.8 GO:0005534 galactose binding(GO:0005534)
0.4 14.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3 2.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 4.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 2.9 GO:0008494 translation activator activity(GO:0008494)
0.3 1.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 1.4 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.2 1.4 GO:0035877 death effector domain binding(GO:0035877)
0.2 6.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 3.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 4.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 4.7 GO:0019003 GDP binding(GO:0019003)
0.1 7.6 GO:0017022 myosin binding(GO:0017022)
0.1 4.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.5 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 2.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 2.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 1.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 10.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 12.2 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 3.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 5.3 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 6.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 7.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 10.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 13.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.8 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 4.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 PID BMP PATHWAY BMP receptor signaling
0.0 3.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 16.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 3.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 7.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 4.1 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.1 1.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 6.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 8.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated